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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115509457
log Bayes Factor = 15.7024
Chromosome 3   position 140,430,992  (GRCh37) Explore rs115509457 on Ensembl!
Variant rs115509457 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.994 0.006 0.000
M48 Other spondylopathies
0.993 0.007 0.000
Z50 Care involving use of rehabilitation procedures
0.991 0.009 0.000
I69 Sequelae of cerebrovascular disease
0.990 0.010 0.000
G40-G47 Episodic and paroxysmal disorders
0.989 0.011 0.000
M48.0 Spinal stenosis
0.989 0.011 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.989 0.011 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.987 0.013 0.000
N81 Female genital prolapse
0.982 0.018 0.000
M20-M25 Other joint disorders
0.980 0.020 0.000
M48.06 Spinal stenosis (Lumbar region)
0.977 0.023 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.963 0.037 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.962 0.038 0.000
N10-N16 Renal tubulo-interstitial diseases
0.961 0.039 0.000
G47 Sleep disorders
0.960 0.040 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.960 0.040 0.000
M25 Other joint disorders, not elsewhere classified
0.959 0.041 0.000
I10-I15 Hypertensive diseases
0.958 0.042 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.957 0.043 0.000
G90-G99 Other disorders of the nervous system
0.953 0.047 0.000
N25-N29 Other disorders of kidney and ureter
0.953 0.047 0.000
G81 Hemiplegia
0.951 0.049 0.000
Z48 Other surgical follow-up care
0.949 0.051 0.000
S00-S09 Injuries to the head
0.948 0.052 0.000
N81.6 Rectocele
0.944 0.056 0.000
M50-M54 Other dorsopathies
0.943 0.057 0.000
N13 Obstructive and reflux uropathy
0.938 0.062 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.933 0.067 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.931 0.069 0.000
M40-M43 Deforming dorsopathies
0.931 0.069 0.000
G81.9 Hemiplegia, unspecified
0.925 0.075 0.000
Z50.8 Care involving use of rehabilitation procedures
0.923 0.077 0.000
M25.7 Osteophyte
0.920 0.080 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.919 0.081 0.000
M70-M79 Other soft tissue disorders
0.918 0.082 0.000
Chapter I Certain infectious and parasitic diseases
0.915 0.085 0.000
G47.3 Sleep apnoea
0.914 0.086 0.000
N13.3 Other and unspecified hydronephrosis
0.912 0.088 0.000
I10 Essential (primary) hypertension
0.910 0.090 0.000
Z60 Problems related to social environment
0.909 0.091 0.000
Chapter X Diseases of the respiratory system
0.908 0.092 0.000
Z48.8 Other specified surgical follow-up care
0.907 0.093 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.904 0.096 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.899 0.101 0.000
M47 Spondylosis
0.897 0.103 0.000
N81.1 Cystocele
0.897 0.103 0.000
G82 Paraplegia and tetraplegia
0.896 0.104 0.000
M48.09 Spinal stenosis (Site unspecified)
0.893 0.107 0.000
G40 Epilepsy
0.892 0.108 0.000
E10-E14 Diabetes mellitus
0.883 0.117 0.000
N81.3 Complete uterovaginal prolapse
0.879 0.121 0.000
I77 Other disorders of arteries and arterioles
0.878 0.122 0.000
Z60.2 Living alone
0.876 0.124 0.000
M25.4 Effusion of joint
0.875 0.125 0.000
I30-I52 Other forms of heart disease
0.874 0.126 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.873 0.127 0.000
S10-S19 Injuries to the neck
0.870 0.130 0.000
S00 Superficial injury of head
0.868 0.132 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.868 0.132 0.000
I60 Subarachnoid haemorrhage
0.864 0.136 0.000
N28.1 Cyst of kidney, acquired
0.864 0.136 0.000
E65-E68 Obesity and other hyperalimentation
0.864 0.136 0.000
Z50.1 Other physical therapy
0.862 0.138 0.000
N87 Dysplasia of cervix uteri
0.862 0.138 0.000
Z49 Care involving dialysis
0.861 0.139 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.860 0.140 0.000
M43 Other deforming dorsopathies
0.860 0.140 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.859 0.141 0.000
M23 Internal derangement of knee
0.859 0.141 0.000
G95 Other diseases of spinal cord
0.859 0.141 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.858 0.142 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.857 0.143 0.000
S50-S59 Injuries to the elbow and forearm
0.847 0.153 0.000
Z47 Other orthopaedic follow-up care
0.844 0.156 0.000
G43 Migraine
0.844 0.156 0.000
M25.78 Osteophyte (Other)
0.843 0.157 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.841 0.159 0.000
Z50.0 Cardiac rehabilitation
0.838 0.162 0.000
N76 Other inflammation of vagina and vulva
0.837 0.163 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.837 0.163 0.000
N00-N08 Glomerular diseases
0.836 0.164 0.000
J30-J39 Other diseases of upper respiratory tract
0.833 0.167 0.000
E70-E90 Metabolic disorders
0.833 0.167 0.000
M47.8 Other spondylosis
0.830 0.170 0.000
M54 Dorsalgia
0.829 0.171 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
M51 Other intervertebral disk disorders
0.828 0.172 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.827 0.173 0.000
A30-A49 Other bacterial diseases
0.827 0.173 0.000
I61 Intracerebral haemorrhage
0.824 0.176 0.000
M71 Other bursopathies
0.824 0.176 0.000
M23.3 Other meniscus derangements
0.822 0.178 0.000
I45 Other conduction disorders
0.821 0.179 0.000
J00-J06 Acute upper respiratory infections
0.818 0.182 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.816 0.184 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.815 0.185 0.000
S06 Intracranial injury
0.813 0.187 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.812 0.188 0.000
S00.9 Superficial injury of head, part unspecified
0.810 0.190 0.000
T91 Sequelae of injuries of neck and trunk
0.810 0.190 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.809 0.190 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.808 0.192 0.000
G40.9 Epilepsy, unspecified
0.808 0.192 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.807 0.193 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.807 0.193 0.000
N20-N23 Urolithiasis
0.806 0.194 0.000
M43.1 Spondylolisthesis
0.803 0.197 0.000
S90-S99 Injuries to the ankle and foot
0.801 0.199 0.000
M72 Fibroblastic disorders
0.799 0.201 0.000
S70-S79 Injuries to the hip and thigh
0.799 0.201 0.000
J60-J70 Lung diseases due to external agents
0.796 0.204 0.000
I38 Endocarditis, valve unspecified
0.795 0.205 0.000
I77.1 Stricture of artery
0.794 0.206 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.794 0.206 0.000
E66 Obesity
0.794 0.206 0.000
M47.86 Other spondylosis (Lumbar region)
0.793 0.207 0.000
N70 Salpingitis and oophoritis
0.792 0.208 0.000
E20-E35 Disorders of other endocrine glands
0.791 0.209 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.791 0.209 0.000
M25.47 Effusion of joint (Ankle and foot)
0.789 0.211 0.000
G47.8 Other sleep disorders
0.788 0.212 0.000
N81.5 Vaginal enterocele
0.787 0.213 0.000
Z57 Occupational exposure to risk-factors
0.787 0.213 0.000
M34 Systemic sclerosis
0.787 0.213 0.000
N71 Inflammatory disease of uterus, except cervix
0.786 0.214 0.000
B25-B34 Other viral diseases
0.786 0.214 0.000
I62 Other nontraumatic intracranial haemorrhage
0.786 0.214 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.785 0.215 0.000
J09-J18 Influenza and pneumonia
0.783 0.217 0.000
G91 Hydrocephalus
0.780 0.220 0.000
M48.02 Spinal stenosis (Cervical region)
0.779 0.221 0.000
I15 Secondary hypertension
0.778 0.222 0.000
Chapter XXII Codes for special purposes
0.777 0.223 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.776 0.224 0.000
I69.3 Sequelae of cerebral infarction
0.776 0.224 0.000
M86-M90 Other osteopathies
0.776 0.224 0.000
S02 Fracture of skull and facial bones
0.774 0.226 0.000
N21 Calculus of lower urinary tract
0.774 0.226 0.000
I67 Other cerebrovascular diseases
0.773 0.227 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.772 0.228 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.769 0.231 0.000
N90.5 Atrophy of vulva
0.769 0.231 0.000
G47.9 Sleep disorder, unspecified
0.768 0.232 0.000
N88 Other noninflammatory disorders of cervix uteri
0.768 0.232 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.768 0.232 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.766 0.234 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
N91 Absent, scanty and rare menstruation
0.765 0.235 0.000
I44 Atrioventricular and left bundle-branch block
0.764 0.236 0.000
E86 Volume depletion
0.764 0.236 0.000
M45 Ankylosing spondylitis
0.762 0.238 0.000
G83 Other paralytic syndromes
0.762 0.238 0.000
E66.9 Obesity, unspecified
0.762 0.238 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.760 0.240 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.759 0.241 0.000
M25.74 Osteophyte (Hand)
0.758 0.242 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.757 0.243 0.000
G82.4 Spastic tetraplegia
0.757 0.243 0.000
Chapter V Mental and behavioural disorders
0.757 0.243 0.000
I73 Other peripheral vascular diseases
0.756 0.244 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.756 0.244 0.000
Z50.2 Alcohol rehabilitation
0.756 0.244 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.755 0.245 0.000
Z48.9 Surgical follow-up care, unspecified
0.755 0.245 0.000
G95.9 Disease of spinal cord, unspecified
0.754 0.246 0.000
O85-O92 Complications predominantly related to the puerperium
0.754 0.246 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.752 0.248 0.000
M80-M85 Disorders of bone density and structure
0.751 0.248 0.000
N81.9 Female genital prolapse, unspecified
0.751 0.249 0.000
N21.0 Calculus in bladder
0.751 0.249 0.000
N13.4 Hydroureter
0.750 0.249 0.000
E14 Unspecified diabetes mellitus
0.750 0.250 0.000
M41 Scoliosis
0.749 0.251 0.000
N94.6 Dysmenorrhoea, unspecified
0.748 0.252 0.000
J00 Acute nasopharyngitis [common cold]
0.747 0.253 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.747 0.253 0.000
E11 Non-insulin-dependent diabetes mellitus
0.746 0.254 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.746 0.254 0.000
M22 Disorders of patella
0.745 0.255 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.745 0.255 0.000
N80 Endometriosis
0.745 0.255 0.000
N28.8 Other specified disorders of kidney and ureter
0.744 0.256 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.744 0.256 0.000
S40-S49 Injuries to the shoulder and upper arm
0.743 0.257 0.000
G90 Disorders of autonomic nervous system
0.742 0.257 0.000
T79-T79 Certain early complications of trauma
0.742 0.258 0.000
A49 Bacterial infection of unspecified site
0.742 0.258 0.000
N72 Inflammatory disease of cervix uteri
0.741 0.259 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.741 0.259 0.000
J33 Nasal polyp
0.741 0.259 0.000
M51.2 Other specified intervertebral disk displacement
0.740 0.260 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.738 0.262 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.737 0.263 0.000
N97 Female infertility
0.737 0.263 0.000
Z41 Procedures for purposes other than remedying health state
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.736 0.264 0.000
N75 Diseases of Bartholin's gland
0.735 0.265 0.000
N94.3 Premenstrual tension syndrome
0.734 0.266 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.734 0.266 0.000
M91-M94 Chondropathies
0.733 0.267 0.000
S80-S89 Injuries to the knee and lower leg
0.733 0.267 0.000
M24 Other specific joint derangements
0.730 0.270 0.000
O80-O84 Delivery
0.730 0.270 0.000
Z49.0 Preparatory care for dialysis
0.730 0.270 0.000
M25.8 Other specified joint disorders
0.729 0.271 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.729 0.271 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.727 0.273 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.727 0.273 0.000
I71 Aortic aneurysm and dissection
0.724 0.275 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.723 0.277 0.000
M25.77 Osteophyte (Ankle and foot)
0.723 0.277 0.000
Z91.6 Personal history of other physical trauma
0.723 0.277 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.722 0.278 0.000
Z52 Donors of organs and tissues
0.722 0.278 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.721 0.279 0.000
M53 Other dorsopathies, not elsewhere classified
0.721 0.279 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.720 0.280 0.000
I45.1 Other and unspecified right bundle-branch block
0.719 0.281 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.719 0.281 0.000
M54.1 Radiculopathy
0.719 0.281 0.000
G95.0 Syringomyelia and syringobulbia
0.718 0.282 0.000
N11 Chronic tubulo-interstitial nephritis
0.718 0.282 0.000
I45.3 Trifascicular block
0.717 0.283 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
S01 Open wound of head
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
Z93 Artificial opening status
0.716 0.284 0.000
J33.0 Polyp of nasal cavity
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.285 0.000
G40.8 Other epilepsy
0.714 0.286 0.000
G82.1 Spastic paraplegia
0.713 0.287 0.000
Z54 Convalescence
0.712 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.712 0.287 0.000
M48.9 Spondylopathy, unspecified
0.712 0.288 0.000
M48.8 Other specified spondylopathies
0.712 0.288 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.712 0.288 0.000
M48.4 Fatigue fracture of vertebra
0.712 0.288 0.000
M48.3 Traumatic spondylopathy
0.712 0.288 0.000
M48.2 Kissing spine
0.712 0.288 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.712 0.288 0.000
G30-G32 Other degenerative diseases of the nervous system
0.711 0.289 0.000
M25.72 Osteophyte (Upper arm)
0.711 0.289 0.000
Z50.6 Orthoptic training
0.711 0.289 0.000
Z50.3 Drug rehabilitation
0.711 0.289 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.710 0.290 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.710 0.290 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.709 0.291 0.000
G41 Status epilepticus
0.709 0.291 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.709 0.291 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.709 0.291 0.000
M48.04 Spinal stenosis (Thoracic region)
0.709 0.291 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.709 0.291 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.709 0.291 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.709 0.291 0.000
G93 Other disorders of brain
0.709 0.291 0.000
N98 Complications associated with artificial fertilisation
0.709 0.291 0.000
N82 Fistulae involving female genital tract
0.709 0.291 0.000
N96 Habitual aborter
0.709 0.291 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.708 0.292 0.000
G80 Infantile cerebral palsy
0.707 0.292 0.000
I12 Hypertensive renal disease
0.708 0.292 0.000
S51 Open wound of forearm
0.707 0.293 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
M54.5 Low back pain
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
S00.3 Superficial injury of nose
0.705 0.295 0.000
I44.2 Atrioventricular block, complete
0.705 0.295 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.705 0.295 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.704 0.296 0.000
M25.71 Osteophyte (Shoulder region)
0.704 0.296 0.000
N81.0 Female urethrocele
0.704 0.296 0.000
M47.2 Other spondylosis with radiculopathy
0.704 0.296 0.000
M46 Other inflammatory spondylopathies
0.704 0.296 0.000
N87.0 Mild cervical dysplasia
0.703 0.297 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.703 0.297 0.000
M33 Dermatopolymyositis
0.703 0.297 0.000
M32 Systemic lupus erythematosus
0.703 0.297 0.000
M30 Polyarteritis nodosa and related conditions
0.703 0.297 0.000
G43.1 Migraine with aura [classical migraine]
0.702 0.298 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.702 0.298 0.000
T85.2 Mechanical complication of intraocular lens
0.702 0.298 0.000
M25.46 Effusion of joint (Lower leg)
0.702 0.298 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.701 0.299 0.000
T86 Failure and rejection of transplanted organs and tissues
0.700 0.300 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.700 0.300 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.700 0.300 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.699 0.300 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.699 0.301 0.000
T98 Sequelae of other and unspecified effects of external causes
0.699 0.301 0.000
Z99.2 Dependence on renal dialysis
0.699 0.301 0.000
O00-O08 Pregnancy with abortive outcome
0.698 0.302 0.000
B95-B98 Bacterial, viral and other infectious agents
0.697 0.303 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.697 0.303 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.697 0.303 0.000
I77.6 Arteritis, unspecified
0.697 0.303 0.000
E40-E46 Malnutrition
0.696 0.304 0.000
I31 Other diseases of pericardium
0.696 0.304 0.000
M35 Other systemic involvement of connective tissue
0.696 0.304 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.695 0.305 0.000
N76.0 Acute vaginitis
0.695 0.305 0.000
M05-M14 Inflammatory polyarthropathies
0.694 0.306 0.000
I99 Other and unspecified disorders of circulatory system
0.694 0.306 0.000
G82.2 Paraplegia, unspecified
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.693 0.307 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.693 0.307 0.000
G82.5 Tetraplegia, unspecified
0.692 0.308 0.000
I63 Cerebral infarction
0.692 0.308 0.000
Z42 Follow-up care involving plastic surgery
0.691 0.309 0.000
S20-S29 Injuries to the thorax
0.690 0.310 0.000
Z88.0 Personal history of allergy to penicillin
0.690 0.310 0.000
G37 Other demyelinating diseases of central nervous system
0.689 0.311 0.000
M31 Other necrotising vasculopathies
0.689 0.311 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.689 0.311 0.000
N15 Other renal tubulo-interstitial diseases
0.689 0.311 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.689 0.311 0.000
N10 Acute tubulo-interstitial nephritis
0.689 0.311 0.000
G47.4 Narcolepsy and cataplexy
0.688 0.311 0.000
G47.2 Disorders of the sleep-wake schedule
0.688 0.311 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.688 0.311 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.688 0.311 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.688 0.312 0.000
N86 Erosion and ectropion of cervix uteri
0.688 0.312 0.000
N03 Chronic nephritic syndrome
0.688 0.312 0.000
M25.9 Joint disorder, unspecified
0.687 0.312 0.000
M25.3 Other instability of joint
0.687 0.312 0.000
M25.2 Flail joint
0.687 0.312 0.000
M25.1 Fistula of joint
0.687 0.312 0.000
M25.0 Haemarthrosis
0.687 0.312 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.687 0.313 0.000
I13 Hypertensive heart and renal disease
0.687 0.313 0.000
I11 Hypertensive heart disease
0.687 0.313 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.687 0.313 0.000
Z65 Problems related to other psychosocial circumstances
0.686 0.314 0.000
Z64 Problems related to certain psychosocial circumstances
0.686 0.314 0.000
Z63 Other problems related to primary support group, including family circumstances
0.686 0.314 0.000
Z62 Other problems related to upbringing
0.686 0.314 0.000
Z61 Problems related to negative life events in childhood
0.686 0.314 0.000
Z59 Problems related to housing and economic circumstances
0.686 0.314 0.000
Z58 Problems related to physical environment
0.686 0.314 0.000
Z56 Problems related to employment and unemployment
0.686 0.314 0.000
Z55 Problems related to education and literacy
0.686 0.314 0.000
N26 Unspecified contracted kidney
0.685 0.315 0.000
S14 Injury of nerves and spinal cord at neck level
0.684 0.315 0.000
Z49.1 Extracorporeal dialysis
0.684 0.316 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
N81.4 Uterovaginal prolapse, unspecified
0.683 0.317 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.683 0.317 0.000
N27 Small kidney of unknown cause
0.683 0.317 0.000
N25 Disorders resulting from impaired renal tubular function
0.683 0.317 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.683 0.317 0.000
B34 Viral infection of unspecified site
0.683 0.317 0.000
S00.0 Superficial injury of scalp
0.683 0.317 0.000
Z29 Need for other prophylactic measures
0.682 0.317 0.000
J18 Pneumonia, organism unspecified
0.682 0.318 0.000
M50 Cervical disk disorders
0.682 0.318 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.682 0.318 0.000
G81.1 Spastic hemiplegia
0.682 0.318 0.000
G81.0 Flaccid hemiplegia
0.682 0.318 0.000
N84 Polyp of female genital tract
0.681 0.319 0.000
G44 Other headache syndromes
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.680 0.320 0.000
S07 Crushing injury of head
0.680 0.320 0.000
S05 Injury of eye and orbit
0.680 0.320 0.000
S04 Injury of cranial nerves
0.680 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.320 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.680 0.320 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.679 0.321 0.000
J32 Chronic sinusitis
0.679 0.321 0.000
L60-L75 Disorders of skin appendages
0.678 0.322 0.000
Z57.3 Occupational exposure to other air contaminants
0.677 0.323 0.000
T91.3 Sequelae of injury of spinal cord
0.676 0.324 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.675 0.325 0.000
N04 Nephrotic syndrome
0.674 0.326 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.673 0.327 0.000
M77 Other enthesopathies
0.673 0.327 0.000
I73.9 Peripheral vascular disease, unspecified
0.673 0.327 0.000
G96 Other disorders of central nervous system
0.673 0.327 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.672 0.327 0.000
N13.6 Pyonephrosis
0.672 0.327 0.000
Z22 Carrier of infectious disease
0.672 0.328 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
E13 Other specified diabetes mellitus
0.672 0.328 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.672 0.328 0.000
M25.76 Osteophyte (Lower leg)
0.669 0.331 0.000
M54.3 Sciatica
0.669 0.331 0.000
L50-L54 Urticaria and erythema
0.669 0.331 0.000
S72 Fracture of femur
0.668 0.332 0.000
G43.9 Migraine, unspecified
0.668 0.332 0.000
M42 Spinal osteochondrosis
0.668 0.332 0.000
M40 Kyphosis and lordosis
0.668 0.332 0.000
G70-G73 Diseases of myoneural junction and muscle
0.667 0.333 0.000
G03 Meningitis due to other and unspecified causes
0.666 0.334 0.000
B15-B19 Viral hepatitis
0.666 0.334 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.665 0.335 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.665 0.335 0.000
Z48.0 Attention to surgical dressings and sutures
0.664 0.336 0.000
M21 Other acquired deformities of limbs
0.663 0.336 0.000
G95.8 Other specified diseases of spinal cord
0.662 0.337 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.662 0.338 0.000
J69 Pneumonitis due to solids and liquids
0.662 0.338 0.000
J35 Chronic diseases of tonsils and adenoids
0.661 0.339 0.000
M79.8 Other specified soft tissue disorders
0.661 0.339 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.660 0.340 0.000
M25.79 Osteophyte (Site unspecified)
0.659 0.341 0.000
M25.73 Osteophyte (Forearm)
0.659 0.341 0.000
M25.70 Osteophyte (Multiple sites)
0.659 0.341 0.000
N28.0 Ischaemia and infarction of kidney
0.659 0.341 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.658 0.342 0.000
M76 Enthesopathies of lower limb, excluding foot
0.658 0.342 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.658 0.342 0.000
E87.6 Hypokalaemia
0.658 0.342 0.000
S60-S69 Injuries to the wrist and hand
0.657 0.343 0.000
Z50.5 Speech therapy
0.657 0.343 0.000
S19 Other and unspecified injuries of neck
0.656 0.343 0.000
G91.9 Hydrocephalus, unspecified
0.656 0.344 0.000
E10 Insulin-dependent diabetes mellitus
0.656 0.344 0.000
N90.6 Hypertrophy of vulva
0.656 0.344 0.000
N76.4 Abscess of vulva
0.656 0.344 0.000
B99-B99 Other infectious diseases
0.656 0.344 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.656 0.344 0.000
B50-B64 Protozoal diseases
0.656 0.344 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.656 0.344 0.000
A75-A79 Rickettsioses
0.656 0.344 0.000
A70-A74 Other diseases caused by chlamydiae
0.656 0.344 0.000
A65-A69 Other spirochaetal diseases
0.656 0.344 0.000
A20-A28 Certain zoonotic bacterial diseases
0.656 0.344 0.000
A15-A19 Tuberculosis
0.656 0.344 0.000
I45.2 Bifascicular block
0.653 0.347 0.000
Z45 Adjustment and management of implanted device
0.653 0.347 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.652 0.348 0.000
Z60.9 Problem related to social environment, unspecified
0.652 0.348 0.000
Z60.8 Other problems related to social environment
0.652 0.348 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.652 0.348 0.000
Z60.4 Social exclusion and rejection
0.652 0.348 0.000
Z60.3 Acculturation difficulty
0.652 0.348 0.000
Z60.1 Atypical parenting situation
0.652 0.348 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.652 0.348 0.000
S06.2 Diffuse brain injury
0.652 0.348 0.000
T90 Sequelae of injuries of head
0.650 0.350 0.000
J31.0 Chronic rhinitis
0.650 0.350 0.000
A40 Streptococcal septicaemia
0.650 0.350 0.000
Z40 Prophylactic surgery
0.649 0.351 0.000
G35 Multiple sclerosis
0.649 0.351 0.000
M34.9 Systemic sclerosis, unspecified
0.649 0.351 0.000
E28 Ovarian dysfunction
0.648 0.352 0.000
I15.1 Hypertension secondary to other renal disorders
0.648 0.352 0.000
N94.5 Secondary dysmenorrhoea
0.648 0.352 0.000
N94.4 Primary dysmenorrhoea
0.648 0.352 0.000
N94.2 Vaginismus
0.648 0.352 0.000
N94.0 Mittelschmerz
0.648 0.352 0.000
I67.8 Other specified cerebrovascular diseases
0.647 0.352 0.000
T92 Sequelae of injuries of upper limb
0.647 0.353 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.646 0.353 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.646 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.646 0.354 0.000
G97.8 Other postprocedural disorders of nervous system
0.646 0.354 0.000
N90.4 Leukoplakia of vulva
0.645 0.355 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.645 0.355 0.000
I74 Arterial embolism and thrombosis
0.645 0.355 0.000
T95 Sequelae of burns, corrosions and frostbite
0.645 0.355 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.645 0.355 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.645 0.355 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.645 0.355 0.000
Chapter XX External causes of morbidity and mortality
0.644 0.356 0.000
I30 Acute pericarditis
0.644 0.356 0.000
M47.1 Other spondylosis with myelopathy
0.643 0.357 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.643 0.357 0.000
Z47.8 Other specified orthopaedic follow-up care
0.643 0.357 0.000
N81.2 Incomplete uterovaginal prolapse
0.643 0.357 0.000
G82.3 Flaccid tetraplegia
0.643 0.357 0.000
G82.0 Flaccid paraplegia
0.643 0.357 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.641 0.359 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.641 0.359 0.000
M43.0 Spondylolysis
0.641 0.359 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.640 0.360 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.640 0.360 0.000
G40.5 Special epileptic syndromes
0.640 0.360 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.640 0.360 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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