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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115578729
log Bayes Factor = 6.02631
Chromosome 1   position 249,125,649  (GRCh37) Explore rs115578729 on Ensembl!
Variant rs115578729 is part of Cluster X0080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.991 0.009 0.000
J43 Emphysema
0.979 0.021 0.000
S80-S89 Injuries to the knee and lower leg
0.979 0.021 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.974 0.026 0.000
S82 Fracture of lower leg, including ankle
0.971 0.029 0.000
J43.9 Emphysema, unspecified
0.964 0.036 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.964 0.036 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.959 0.041 0.000
M70-M79 Other soft tissue disorders
0.957 0.043 0.000
M45-M49 Spondylopathies
0.954 0.046 0.000
M07 Psoriatic and enteropathic arthropathies
0.952 0.048 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.952 0.048 0.000
M50 Cervical disk disorders
0.947 0.053 0.000
M51 Other intervertebral disk disorders
0.946 0.054 0.000
M75 Shoulder lesions
0.943 0.057 0.000
M86-M90 Other osteopathies
0.939 0.061 0.000
E70-E90 Metabolic disorders
0.939 0.061 0.000
E86 Volume depletion
0.938 0.062 0.000
M50.0 Cervical disk disorder with myelopathy
0.937 0.063 0.000
M75.0 Adhesive capsulitis of shoulder
0.936 0.064 0.000
M47 Spondylosis
0.932 0.068 0.000
S82.4 Fracture of fibula alone
0.926 0.074 0.000
M07.3 Other psoriatic arthropathies
0.924 0.076 0.000
T51 Toxic effect of alcohol
0.922 0.078 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.920 0.080 0.000
M54 Dorsalgia
0.919 0.081 0.000
M06 Other rheumatoid arthritis
0.917 0.083 0.000
S60-S69 Injuries to the wrist and hand
0.913 0.087 0.000
S61.0 Open wound of finger(s) without damage to nail
0.908 0.092 0.000
S61 Open wound of wrist and hand
0.907 0.093 0.000
M47.8 Other spondylosis
0.905 0.095 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.903 0.097 0.000
T66-T78 Other and unspecified effects of external causes
0.895 0.104 0.000
S82.40 Fracture of fibula alone (closed)
0.895 0.105 0.000
J90-J94 Other diseases of pleura
0.892 0.108 0.000
M47.82 Other spondylosis (Cervical region)
0.890 0.110 0.000
T51.0 Ethanol
0.886 0.114 0.000
J95-J99 Other diseases of the respiratory system
0.884 0.116 0.000
Chapter VI Diseases of the nervous system
0.883 0.117 0.000
M89 Other disorders of bone
0.882 0.118 0.000
M60-M63 Disorders of muscles
0.879 0.121 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.876 0.124 0.000
M40-M43 Deforming dorsopathies
0.868 0.132 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.863 0.137 0.000
S10-S19 Injuries to the neck
0.854 0.146 0.000
J46 Status asthmaticus
0.851 0.149 0.000
M10 Gout
0.850 0.150 0.000
M54.9 Dorsalgia, unspecified
0.850 0.150 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.848 0.152 0.000
T78 Adverse effects, not elsewhere classified
0.842 0.158 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.839 0.161 0.000
T42.4 Benzodiazepines
0.837 0.163 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.836 0.164 0.000
J09-J18 Influenza and pneumonia
0.833 0.167 0.000
G90-G99 Other disorders of the nervous system
0.829 0.171 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.829 0.171 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.825 0.175 0.000
M89.9 Disorder of bone, unspecified
0.822 0.178 0.000
S82.0 Fracture of patella
0.822 0.178 0.000
M51.9 Intervertebral disk disorder, unspecified
0.822 0.178 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.821 0.179 0.000
J92 Pleural plaque
0.816 0.183 0.000
S82.5 Fracture of medial malleolus
0.808 0.192 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.806 0.194 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.805 0.195 0.000
M51.2 Other specified intervertebral disk displacement
0.803 0.197 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.801 0.199 0.000
S82.8 Fractures of other parts of lower leg
0.800 0.200 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.799 0.201 0.000
S61.1 Open wound of finger(s) with damage to nail
0.795 0.205 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.794 0.206 0.000
J98 Other respiratory disorders
0.791 0.209 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.791 0.209 0.000
M47.9 Spondylosis, unspecified
0.787 0.213 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.786 0.214 0.000
M06.9 Rheumatoid arthritis, unspecified
0.785 0.215 0.000
J20-J22 Other acute lower respiratory infections
0.784 0.216 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.783 0.217 0.000
M80-M85 Disorders of bone density and structure
0.783 0.217 0.000
S82.2 Fracture of shaft of tibia
0.783 0.217 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.780 0.220 0.000
M47.86 Other spondylosis (Lumbar region)
0.770 0.230 0.000
T51.9 Alcohol, unspecified
0.769 0.231 0.000
J94 Other pleural conditions
0.767 0.233 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.766 0.234 0.000
T21 Burn and corrosion of trunk
0.765 0.235 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.764 0.236 0.000
M06.3 Rheumatoid nodule
0.762 0.238 0.000
S89 Other and unspecified injuries of lower leg
0.757 0.243 0.000
E65-E68 Obesity and other hyperalimentation
0.753 0.247 0.000
T45.0 Antiallergic and antiemetic drugs
0.752 0.248 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.752 0.248 0.000
M62 Other disorders of muscle
0.751 0.249 0.000
G83 Other paralytic syndromes
0.751 0.249 0.000
T78.4 Allergy, unspecified
0.751 0.249 0.000
E89.0 Postprocedural hypothyroidism
0.748 0.252 0.000
M51.8 Other specified intervertebral disk disorders
0.747 0.253 0.000
M43 Other deforming dorsopathies
0.746 0.254 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.745 0.255 0.000
M75.4 Impingement syndrome of shoulder
0.745 0.255 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.744 0.256 0.000
M05 Seropositive rheumatoid arthritis
0.743 0.257 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.743 0.257 0.000
J98.1 Pulmonary collapse
0.742 0.258 0.000
M14 Arthropathies in other diseases classified elsewhere
0.741 0.259 0.000
E20-E35 Disorders of other endocrine glands
0.737 0.263 0.000
S82.7 Multiple fractures of lower leg
0.735 0.265 0.000
M54.3 Sciatica
0.735 0.265 0.000
T79-T79 Certain early complications of trauma
0.734 0.266 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.733 0.267 0.000
E40-E46 Malnutrition
0.732 0.268 0.000
T23 Burn and corrosion of wrist and hand
0.732 0.268 0.000
S82.1 Fracture of upper end of tibia
0.729 0.271 0.000
M84 Disorders of continuity of bone
0.728 0.272 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.728 0.272 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.728 0.272 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.726 0.274 0.000
J91 Pleural effusion in conditions classified elsewhere
0.726 0.274 0.000
M86 Osteomyelitis
0.724 0.276 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.723 0.277 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.722 0.277 0.000
M47.1 Other spondylosis with myelopathy
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.721 0.279 0.000
J92.0 Pleural plaque with presence of asbestos
0.720 0.280 0.000
M10.9 Gout, unspecified
0.718 0.282 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
S82.81 Fractures of other parts of lower leg (open)
0.714 0.286 0.000
G20-G26 Extrapyramidal and movement disorders
0.714 0.286 0.000
M06.0 Seronegative rheumatoid arthritis
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.713 0.287 0.000
M11 Other crystal arthropathies
0.712 0.288 0.000
M54.5 Low back pain
0.712 0.288 0.000
S14 Injury of nerves and spinal cord at neck level
0.712 0.288 0.000
M60 Myositis
0.711 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.289 0.000
M12 Other specific arthropathies
0.711 0.289 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.711 0.289 0.000
M08 Juvenile arthritis
0.711 0.289 0.000
T20 Burn and corrosion of head and neck
0.711 0.289 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.710 0.290 0.000
J42 Unspecified chronic bronchitis
0.710 0.290 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.710 0.290 0.000
M54.1 Radiculopathy
0.710 0.290 0.000
T78.2 Anaphylactic shock, unspecified
0.706 0.294 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.705 0.295 0.000
S68 Traumatic amputation of wrist and hand
0.705 0.295 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.704 0.295 0.000
M75.5 Bursitis of shoulder
0.704 0.296 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.704 0.296 0.000
S65 Injury of blood vessels at wrist and hand level
0.702 0.298 0.000
J43.8 Other emphysema
0.702 0.298 0.000
J43.2 Centrilobular emphysema
0.702 0.298 0.000
J43.1 Panlobular emphysema
0.702 0.298 0.000
J43.0 MacLeod's syndrome
0.702 0.298 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
S88 Traumatic amputation of lower leg
0.702 0.298 0.000
S87 Crushing injury of lower leg
0.702 0.298 0.000
S85 Injury of blood vessels at lower leg level
0.702 0.298 0.000
S84 Injury of nerves at lower leg level
0.702 0.298 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.702 0.298 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.702 0.298 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.701 0.299 0.000
E85 Amyloidosis
0.701 0.299 0.000
M49 Spondylopathies in diseases classified elsewhere
0.699 0.301 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.698 0.302 0.000
S81 Open wound of lower leg
0.697 0.303 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.697 0.303 0.000
G81 Hemiplegia
0.697 0.303 0.000
M91-M94 Chondropathies
0.696 0.304 0.000
S82.9 Fracture of lower leg, part unspecified
0.696 0.304 0.000
M90 Osteopathies in diseases classified elsewhere
0.695 0.304 0.000
M88 Paget's disease of bone [osteitis deformans]
0.694 0.306 0.000
S82.50 Fracture of medial malleolus (closed)
0.691 0.309 0.000
M06.4 Inflammatory polyarthropathy
0.690 0.310 0.000
J14 Pneumonia due to Haemophilus influenzae
0.690 0.310 0.000
M76 Enthesopathies of lower limb, excluding foot
0.688 0.312 0.000
M54.8 Other dorsalgia
0.688 0.312 0.000
S40-S49 Injuries to the shoulder and upper arm
0.688 0.312 0.000
J92.9 Pleural plaque without asbestos
0.687 0.313 0.000
T58 Toxic effect of carbon monoxide
0.686 0.314 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.686 0.314 0.000
M89.5 Osteolysis
0.684 0.316 0.000
S82.6 Fracture of lateral malleolus
0.683 0.317 0.000
E50-E64 Other nutritional deficiencies
0.683 0.317 0.000
M07.6 Other enteropathic arthropathies
0.682 0.317 0.000
M07.5 Arthropathy in ulcerative colitis
0.682 0.317 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.682 0.317 0.000
M07.2 Psoriatic spondylitis
0.682 0.317 0.000
M07.1 Arthritis mutilans
0.682 0.317 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.682 0.317 0.000
T65 Toxic effect of other and unspecified substances
0.682 0.318 0.000
T62 Toxic effect of other noxious substances eaten as food
0.682 0.318 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.682 0.318 0.000
T60 Toxic effect of pesticides
0.682 0.318 0.000
T59 Toxic effect of other gases, fumes and vapours
0.682 0.318 0.000
T57 Toxic effect of other inorganic substances
0.682 0.318 0.000
T56 Toxic effect of metals
0.682 0.318 0.000
T54 Toxic effect of corrosive substances
0.682 0.318 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.682 0.318 0.000
T52 Toxic effect of organic solvents
0.682 0.318 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.682 0.318 0.000
T55 Toxic effect of soaps and detergents
0.682 0.318 0.000
G83.4 Cauda equina syndrome
0.681 0.319 0.000
M75.1 Rotator cuff syndrome
0.680 0.320 0.000
M50.9 Cervical disk disorder, unspecified
0.679 0.321 0.000
M50.8 Other cervical disk disorders
0.679 0.321 0.000
M48 Other spondylopathies
0.679 0.321 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.679 0.321 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.679 0.321 0.000
M51.3 Other specified intervertebral disk degeneration
0.678 0.321 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.678 0.321 0.000
M51.4 Schmorl's nodes
0.678 0.321 0.000
J12 Viral pneumonia, not elsewhere classified
0.679 0.321 0.000
S86 Injury of muscle and tendon at lower leg level
0.678 0.322 0.000
M75.9 Shoulder lesion, unspecified
0.678 0.322 0.000
M40 Kyphosis and lordosis
0.678 0.322 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.678 0.322 0.000
M45 Ankylosing spondylitis
0.677 0.323 0.000
M75.8 Other shoulder lesions
0.676 0.324 0.000
G90 Disorders of autonomic nervous system
0.675 0.325 0.000
T40.2 Other opioids
0.674 0.326 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.674 0.326 0.000
E84 Cystic fibrosis
0.673 0.327 0.000
E79 Disorders of purine and pyrimidine metabolism
0.673 0.327 0.000
E77 Disorders of glycoprotein metabolism
0.673 0.327 0.000
E76 Disorders of glycosaminoglycan metabolism
0.673 0.327 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.673 0.327 0.000
E74 Other disorders of carbohydrate metabolism
0.673 0.327 0.000
E72 Other disorders of amino-acid metabolism
0.673 0.327 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.673 0.327 0.000
E70 Disorders of aromatic amino-acid metabolism
0.673 0.327 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.673 0.327 0.000
S12 Fracture of neck
0.672 0.328 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.672 0.328 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.671 0.329 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.669 0.331 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.668 0.332 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.668 0.332 0.000
S82.00 Fracture of patella (closed)
0.668 0.332 0.000
M00-M03 Infectious arthropathies
0.668 0.332 0.000
M10.0 Idiopathic gout
0.667 0.333 0.000
J40 Bronchitis, not specified as acute or chronic
0.666 0.334 0.000
S82.41 Fracture of fibula alone (open)
0.664 0.336 0.000
T43.6 Psychostimulants with abuse potential
0.664 0.336 0.000
M10.99 Gout, unspecified (Site unspecified)
0.663 0.337 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.337 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.663 0.337 0.000
E89.2 Postprocedural hypoparathyroidism
0.663 0.337 0.000
M07.38 Other psoriatic arthropathies (Other)
0.662 0.337 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.662 0.337 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.662 0.337 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.662 0.337 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.662 0.337 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.662 0.337 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.662 0.337 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.662 0.337 0.000
S82.01 Fracture of patella (open)
0.662 0.338 0.000
T51.8 Other alcohols
0.661 0.339 0.000
T51.3 Fusel oil
0.661 0.339 0.000
T51.2 2-Propanol
0.661 0.339 0.000
T51.1 Methanol
0.661 0.339 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.661 0.339 0.000
T25 Burn and corrosion of ankle and foot
0.660 0.340 0.000
M62.8 Other specified disorders of muscle
0.659 0.341 0.000
T14 Injury of unspecified body region
0.659 0.341 0.000
M54.0 Panniculitis affecting regions of neck and back
0.659 0.341 0.000
J60-J70 Lung diseases due to external agents
0.658 0.342 0.000
T42.1 Iminostilbenes
0.658 0.342 0.000
M06.8 Other specified rheumatoid arthritis
0.657 0.343 0.000
M06.2 Rheumatoid bursitis
0.657 0.343 0.000
M06.1 Adult-onset Still's disease
0.657 0.343 0.000
J93 Pneumothorax
0.657 0.343 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.655 0.345 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.654 0.346 0.000
M89.0 Algoneurodystrophy
0.652 0.348 0.000
S82.21 Fracture of shaft of tibia (open)
0.652 0.348 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.649 0.351 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.649 0.351 0.000
M47.84 Other spondylosis (Thoracic region)
0.649 0.351 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.649 0.351 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.649 0.351 0.000
M87 Osteonecrosis
0.648 0.352 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.647 0.353 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.647 0.353 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.647 0.353 0.000
T42.3 Barbiturates
0.647 0.353 0.000
T42.2 Succinimides and oxazolidinediones
0.647 0.353 0.000
T42.0 Hydantoin derivatives
0.647 0.353 0.000
M54.4 Lumbago with sciatica
0.647 0.353 0.000
T17 Foreign body in respiratory tract
0.646 0.353 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.646 0.354 0.000
M89.8 Other specified disorders of bone
0.645 0.355 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.645 0.355 0.000
M71 Other bursopathies
0.643 0.356 0.000
T75 Effects of other external causes
0.642 0.358 0.000
T74 Maltreatment syndromes
0.642 0.358 0.000
T73 Effects of other deprivation
0.642 0.358 0.000
T70 Effects of air pressure and water pressure
0.642 0.358 0.000
T69 Other effects of reduced temperature
0.642 0.358 0.000
T67 Effects of heat and light
0.642 0.358 0.000
T71 Asphyxiation
0.642 0.358 0.000
T66 Unspecified effects of radiation
0.642 0.358 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.641 0.359 0.000
M43.1 Spondylolisthesis
0.641 0.359 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.639 0.361 0.000
G37 Other demyelinating diseases of central nervous system
0.638 0.362 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.637 0.363 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.637 0.363 0.000
J17 Pneumonia in diseases classified elsewhere
0.637 0.363 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.636 0.364 0.000
T63 Toxic effect of contact with venomous animals
0.636 0.364 0.000
J94.2 Haemothorax
0.634 0.366 0.000
J18 Pneumonia, organism unspecified
0.634 0.366 0.000
J96 Respiratory failure, not elsewhere classified
0.634 0.366 0.000
T21.3 Burn of third degree of trunk
0.634 0.366 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.633 0.367 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.633 0.367 0.000
M89.6 Osteopathy after poliomyelitis
0.632 0.368 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.632 0.368 0.000
M89.3 Hypertrophy of bone
0.632 0.368 0.000
M89.2 Other disorders of bone development and growth
0.632 0.368 0.000
M89.1 Epiphyseal arrest
0.632 0.368 0.000
M65-M68 Disorders of synovium and tendon
0.632 0.368 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.632 0.368 0.000
E88 Other metabolic disorders
0.631 0.369 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.631 0.369 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.630 0.370 0.000
M61 Calcification and ossification of muscle
0.630 0.370 0.000
S82.3 Fracture of lower end of tibia
0.629 0.371 0.000
M05.8 Other seropositive rheumatoid arthritis
0.629 0.371 0.000
E24 Cushing's syndrome
0.629 0.371 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.629 0.371 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.629 0.371 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.628 0.372 0.000
T45.8 Other primarily systemic and haematological agents
0.628 0.372 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.628 0.372 0.000
T45.6 Fibrinolysis-affecting drugs
0.628 0.372 0.000
T45.5 Anticoagulants
0.628 0.372 0.000
T45.4 Iron and its compounds
0.628 0.372 0.000
T45.3 Enzymes, not elsewhere classified
0.628 0.372 0.000
T45.2 Vitamins, not elsewhere classified
0.628 0.372 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.625 0.375 0.000
M41 Scoliosis
0.624 0.376 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.623 0.376 0.000
M42 Spinal osteochondrosis
0.623 0.377 0.000
T40.4 Other synthetic narcotics
0.623 0.377 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.622 0.378 0.000
J94.8 Other specified pleural conditions
0.619 0.381 0.000
S10 Superficial injury of neck
0.619 0.381 0.000
M54.57 Low back pain (Lumbosacral region)
0.616 0.383 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.613 0.387 0.000
S17 Crushing injury of neck
0.612 0.388 0.000
S15 Injury of blood vessels at neck level
0.612 0.388 0.000
S11 Open wound of neck
0.612 0.388 0.000
S18 Traumatic amputation at neck level
0.612 0.388 0.000
S16 Injury of muscle and tendon at neck level
0.612 0.388 0.000
E83 Disorders of mineral metabolism
0.610 0.390 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.610 0.390 0.000
M10.4 Other secondary gout
0.610 0.390 0.000
M10.3 Gout due to impairment of renal function
0.610 0.390 0.000
M10.2 Drug-induced gout
0.610 0.390 0.000
M10.1 Lead-induced gout
0.610 0.390 0.000
S14.1 Other and unspecified injuries of cervical spinal cord
0.610 0.390 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.609 0.390 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.609 0.390 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.609 0.390 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.609 0.390 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.609 0.390 0.000
J98.9 Respiratory disorder, unspecified
0.609 0.391 0.000
M54.6 Pain in thoracic spine
0.609 0.391 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.608 0.392 0.000
T43.9 Psychotropic drug, unspecified
0.608 0.392 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.608 0.392 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.608 0.392 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.608 0.392 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.607 0.393 0.000
M54.37 Sciatica (Lumbosacral region)
0.606 0.394 0.000
G81.9 Hemiplegia, unspecified
0.606 0.394 0.000
T78.9 Adverse effect, unspecified
0.604 0.396 0.000
T78.8 Other adverse effects, not elsewhere classified
0.604 0.396 0.000
G00 Bacterial meningitis, not elsewhere classified
0.603 0.396 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.602 0.398 0.000
S90-S99 Injuries to the ankle and foot
0.601 0.399 0.000
M72 Fibroblastic disorders
0.601 0.399 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.600 0.400 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.599 0.400 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.599 0.400 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.599 0.400 0.000
E89.5 Postprocedural testicular hypofunction
0.599 0.400 0.000
E89.4 Postprocedural ovarian failure
0.599 0.400 0.000
E89.1 Postprocedural hypoinsulinaemia
0.599 0.400 0.000
M50.3 Other cervical disk degeneration
0.599 0.401 0.000
G24 Dystonia
0.599 0.401 0.000
E65 Localised adiposity
0.598 0.402 0.000
S89.9 Unspecified injury of lower leg
0.597 0.402 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.597 0.403 0.000
J09 Influenza due to certain identified influenza virus
0.597 0.403 0.000
E73 Lactose intolerance
0.597 0.403 0.000
T23.3 Burn of third degree of wrist and hand
0.597 0.403 0.000
D50-D53 Nutritional anaemias
0.597 0.403 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.597 0.403 0.000
Chapter I Certain infectious and parasitic diseases
0.596 0.404 0.000
G82 Paraplegia and tetraplegia
0.595 0.405 0.000
J22 Unspecified acute lower respiratory infection
0.595 0.405 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.594 0.405 0.000
G92 Toxic encephalopathy
0.594 0.405 0.000
T38.9 Other and unspecified hormone antagonists
0.594 0.405 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.594 0.405 0.000
T38.7 Androgens and anabolic congeners
0.594 0.405 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.594 0.405 0.000
T38.5 Other oestrogens and progestogens
0.594 0.405 0.000
T38.4 Oral contraceptives
0.594 0.405 0.000
T38.2 Antithyroid drugs
0.594 0.405 0.000
T38.1 Thyroid hormones and substitutes
0.594 0.405 0.000
T38.0 Glucocorticoids and synthetic analogues
0.594 0.405 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.594 0.406 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.593 0.407 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.593 0.407 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.592 0.408 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.592 0.408 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.590 0.410 0.000
M89.98 Disorder of bone, unspecified (Other)
0.590 0.410 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.590 0.410 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.590 0.410 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.590 0.410 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.590 0.410 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.590 0.410 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.590 0.410 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.590 0.410 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.589 0.410 0.000
J20 Acute bronchitis
0.589 0.411 0.000
T39.0 Salicylates
0.589 0.411 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.588 0.412 0.000
T40.8 Lysergide [LSD]
0.588 0.412 0.000
T40.7 Cannabis (derivatives)
0.588 0.412 0.000
T40.6 Other and unspecified narcotics
0.588 0.412 0.000
T40.5 Cocaine
0.588 0.412 0.000
T40.3 Methadone
0.588 0.412 0.000
T40.1 Heroin
0.588 0.412 0.000
T40.0 Opium
0.588 0.412 0.000
M75.3 Calcific tendinitis of shoulder
0.587 0.413 0.000
J47 Bronchiectasis
0.584 0.416 0.000
G95 Other diseases of spinal cord
0.584 0.416 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.584 0.416 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.583 0.417 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.582 0.418 0.000
T91 Sequelae of injuries of neck and trunk
0.582 0.418 0.000
T21.0 Burn of unspecified degree of trunk
0.581 0.418 0.000
D72 Other disorders of white blood cells
0.582 0.418 0.000
M77 Other enthesopathies
0.581 0.419 0.000
M85 Other disorders of bone density and structure
0.581 0.419 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.580 0.420 0.000
S60 Superficial injury of wrist and hand
0.580 0.420 0.000
M06.34 Rheumatoid nodule (Hand)
0.579 0.420 0.000
S82.51 Fracture of medial malleolus (open)
0.579 0.421 0.000
J21 Acute bronchiolitis
0.579 0.421 0.000
E61 Deficiency of other nutrient elements
0.579 0.421 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.579 0.421 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.579 0.421 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.578 0.422 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.578 0.422 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.578 0.422 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.578 0.422 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.578 0.422 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.578 0.422 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.578 0.422 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.578 0.422 0.000
T44.0 Anticholinesterase agents
0.578 0.422 0.000
Q50-Q56 Congenital malformations of genital organs
0.578 0.422 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.577 0.423 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.577 0.423 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.577 0.423 0.000
G80 Infantile cerebral palsy
0.576 0.424 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.576 0.424 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.576 0.424 0.000
T13 Other injuries of lower limb, level unspecified
0.574 0.425 0.000
T11 Other injuries of upper limb, level unspecified
0.574 0.425 0.000
T09 Other injuries of spine and trunk, level unspecified
0.574 0.425 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.574 0.425 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.574 0.425 0.000
T12 Fracture of lower limb, level unspecified
0.574 0.425 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.574 0.425 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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