TreeWAS – Variant ID: rs11597390

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.975	0.025
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.023	0.977	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.982	0.018
K75.0 Abscess of liver	0.000	0.988	0.012
K04.7 Periapical abscess without sinus	0.000	0.988	0.012
K70.3 Alcoholic cirrhosis of liver	0.000	0.988	0.012
K75 Other inflammatory liver diseases	0.000	0.989	0.011
K70 Alcoholic liver disease	0.000	0.989	0.011
K70-K77 Diseases of liver	0.000	0.990	0.010
K74 Fibrosis and cirrhosis of liver	0.000	0.990	0.010
K70.9 Alcoholic liver disease, unspecified	0.000	0.990	0.010
Z83.5 Family history of eye and ear disorders	0.009	0.991	0.000
H10.9 Conjunctivitis, unspecified	0.009	0.991	0.000
K75.4 Autoimmune hepatitis	0.000	0.991	0.009
K70.4 Alcoholic hepatic failure	0.000	0.991	0.009
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.991	0.009
K72 Hepatic failure, not elsewhere classified	0.000	0.991	0.009
K74.3 Primary biliary cirrhosis	0.000	0.991	0.009
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.991	0.009
K74.5 Biliary cirrhosis, unspecified	0.000	0.991	0.009
M54.9 Dorsalgia, unspecified	0.000	0.991	0.009
K72.9 Hepatic failure, unspecified	0.000	0.992	0.008
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.992	0.008
K75.8 Other specified inflammatory liver diseases	0.000	0.992	0.008
K75.2 Nonspecific reactive hepatitis	0.000	0.992	0.008
K75.1 Phlebitis of portal vein	0.000	0.992	0.008
K75.9 Inflammatory liver disease, unspecified	0.000	0.992	0.008
K70.1 Alcoholic hepatitis	0.000	0.992	0.008
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.992	0.008
K74.0 Hepatic fibrosis	0.000	0.992	0.008
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.992	0.008
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.992	0.008
K77 Liver disorders in diseases classified elsewhere	0.000	0.992	0.007
K74.4 Secondary biliary cirrhosis	0.000	0.993	0.007
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.993	0.007
K74.1 Hepatic sclerosis	0.000	0.993	0.007
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.993	0.007
K72.1 Chronic hepatic failure	0.000	0.993	0.007
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.993	0.007
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.993	0.007
Z89.4 Acquired absence of foot and ankle	0.000	0.993	0.007
K71 Toxic liver disease	0.000	0.993	0.006
D69.6 Thrombocytopenia, unspecified	0.007	0.993	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.993	0.006
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.994	0.006
K72.0 Acute and subacute hepatic failure	0.000	0.994	0.006
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.994	0.006
K04 Diseases of pulp and periapical tissues	0.000	0.994	0.006
K74.6 Other and unspecified cirrhosis of liver	0.000	0.994	0.006
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.994	0.006
K26.7 Chronic without haemorrhage or perforation	0.000	0.994	0.006
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.994	0.006
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.994	0.006
K70.0 Alcoholic fatty liver	0.000	0.994	0.006
K73 Chronic hepatitis, not elsewhere classified	0.000	0.994	0.006
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.994	0.006
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.994	0.006
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.994	0.006
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.994	0.006
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.994	0.006
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.994	0.006
K04.5 Chronic apical periodontitis	0.000	0.994	0.006
N73.6 Female pelvic peritoneal adhesions	0.000	0.994	0.006
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.994	0.005
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.005
H10 Conjunctivitis	0.006	0.994	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.995	0.005
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.005	0.995	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.995	0.005
K76 Other diseases of liver	0.000	0.995	0.005
D32.0 Cerebral meninges	0.000	0.995	0.005
B99 Other and unspecified infectious diseases	0.000	0.995	0.005
K04.0 Pulpitis	0.000	0.995	0.005
K71.9 Toxic liver disease, unspecified	0.000	0.995	0.005
K71.8 Toxic liver disease with other disorders of liver	0.000	0.995	0.005
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.995	0.005
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.995	0.005
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.995	0.005
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.995	0.005
K71.2 Toxic liver disease with acute hepatitis	0.000	0.995	0.005
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.995	0.005
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.995	0.005
N13.8 Other obstructive and reflux uropathy	0.000	0.995	0.005
S32.0 Fracture of lumbar vertebra	0.000	0.995	0.005
Z89.5 Acquired absence of leg at or below knee	0.000	0.995	0.005
K04.3 Abnormal hard tissue formation in pulp	0.000	0.995	0.005
K04.2 Pulp degeneration	0.000	0.995	0.005
K04.1 Necrosis of pulp	0.000	0.995	0.005
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.995	0.005
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.005	0.995	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.995	0.004
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.995	0.005
D69 Purpura and other haemorrhagic conditions	0.005	0.995	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.995	0.004
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.995	0.004
H10.4 Chronic conjunctivitis	0.004	0.995	0.000
H10.5 Blepharoconjunctivitis	0.004	0.995	0.000
Z89 Acquired absence of limb	0.000	0.995	0.005
D69.9 Haemorrhagic condition, unspecified	0.004	0.995	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.995	0.004
K71.0 Toxic liver disease with cholestasis	0.000	0.996	0.004
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.996	0.004
H10.3 Acute conjunctivitis, unspecified	0.004	0.996	0.000
H10.8 Other conjunctivitis	0.004	0.996	0.000
H10.2 Other acute conjunctivitis	0.004	0.996	0.000
H10.1 Acute atopic conjunctivitis	0.004	0.996	0.000
H10.0 Mucopurulent conjunctivitis	0.004	0.996	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.004	0.996	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.996	0.004
D69.8 Other specified haemorrhagic conditions	0.004	0.996	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.996	0.004
K76.4 Peliosis hepatis	0.000	0.996	0.004
K76.3 Infarction of liver	0.000	0.996	0.004
K76.2 Central haemorrhagic necrosis of liver	0.000	0.996	0.004
K73.9 Chronic hepatitis, unspecified	0.000	0.996	0.004
K76.1 Chronic passive congestion of liver	0.000	0.996	0.004
N73 Other female pelvic inflammatory diseases	0.000	0.996	0.004
D32.9 Meninges, unspecified	0.000	0.996	0.004
L28.0 Lichen simplex chronicus	0.004	0.996	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.996	0.004
D69.0 Allergic purpura	0.004	0.996	0.000
K76.6 Portal hypertension	0.000	0.996	0.004
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.996	0.004
S32.01 Fracture of lumbar vertebra (open)	0.000	0.996	0.004
S06 Intracranial injury	0.004	0.996	0.000
D32 Benign neoplasm of meninges	0.000	0.996	0.004
G61.0 Guillain-Barre syndrome	0.004	0.996	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.996	0.004
S52.10 Fracture of upper end of radius (closed)	0.004	0.996	0.000
D69.1 Qualitative platelet defects	0.003	0.996	0.000
K04.6 Periapical abscess with sinus	0.000	0.996	0.004
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.996	0.003
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.996	0.003
Z89.1 Acquired absence of hand and wrist	0.000	0.996	0.003
C77.3 Axillary and upper limb lymph nodes	0.000	0.996	0.004
D69.4 Other primary thrombocytopenia	0.003	0.996	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.997	0.003
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.997	0.003
T51.9 Alcohol, unspecified	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.003	0.997	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
S06.4 Epidural haemorrhage	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
K76.7 Hepatorenal syndrome	0.000	0.997	0.003
Q60.0 Renal agenesis, unilateral	0.000	0.997	0.003
S06.8 Other intracranial injuries	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.997	0.003
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.997	0.003
M46 Other inflammatory spondylopathies	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.003	0.997	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.003	0.997	0.000
N73.4 Female chronic pelvic peritonitis	0.000	0.997	0.003
N73.3 Female acute pelvic peritonitis	0.000	0.997	0.003
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.997	0.003
K40 Inguinal hernia	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.003	0.997	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.997	0.003
D32.1 Spinal meninges	0.000	0.997	0.003
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.997	0.003
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.997	0.003
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
S06.3 Focal brain injury	0.003	0.997	0.000
N73.5 Female pelvic peritonitis, unspecified	0.000	0.997	0.003
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.997	0.003
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.997	0.003
S20 Superficial injury of thorax	0.000	0.997	0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.997	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.997	0.002
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.997	0.002
L28 Lichen simplex chronicus and prurigo	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
M46.8 Other specified inflammatory spondylopathies	0.000	0.997	0.002
M46.5 Other infective spondylopathies	0.000	0.997	0.002
Z89.2 Acquired absence of upper limb above wrist	0.000	0.997	0.002
X78.0 Home	0.000	0.997	0.002
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.997	0.003
M46.2 Osteomyelitis of vertebra	0.000	0.997	0.002
S20.3 Other superficial injuries of front wall of thorax	0.000	0.997	0.003
L50.0 Allergic urticaria	0.003	0.997	0.000
S20.4 Other superficial injuries of back wall of thorax	0.000	0.997	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.997	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.002	0.997	0.000
M46.0 Spinal enthesopathy	0.000	0.997	0.002
D39.1 Ovary	0.002	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.000	0.998	0.002
S06.0 Concussion	0.002	0.998	0.000
M46.4 Discitis, unspecified	0.000	0.998	0.002
Z42 Follow-up care involving plastic surgery	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
S20.1 Other and unspecified superficial injuries of breast	0.000	0.998	0.002
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.000	0.998	0.002
K04.8 Radicular cyst	0.000	0.998	0.002
L28.1 Prurigo nodularis	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.002	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.998	0.002
R90.0 Intracranial space-occupying lesion	0.000	0.998	0.002
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
B99-B99 Other infectious diseases	0.000	0.998	0.002
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.998	0.002
S20.2 Contusion of thorax	0.000	0.998	0.002
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.000	0.998	0.002
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.000	0.998	0.002
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.000	0.998	0.002
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.000	0.998	0.002
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.000	0.998	0.002
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.000	0.998	0.002
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.000	0.998	0.002
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
K26 Duodenal ulcer	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.000	0.998	0.002
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
L28.2 Other prurigo	0.002	0.998	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.000	0.998	0.002
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.57 Other infective spondylopathies (Lumbosacral region)	0.000	0.998	0.002
M46.56 Other infective spondylopathies (Lumbar region)	0.000	0.998	0.002
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.000	0.998	0.002
M46.54 Other infective spondylopathies (Thoracic region)	0.000	0.998	0.002
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.000	0.998	0.002
M46.52 Other infective spondylopathies (Cervical region)	0.000	0.998	0.002
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.000	0.998	0.002
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.000	0.998	0.002
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.000	0.998	0.002
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.000	0.998	0.002
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.000	0.998	0.002
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.000	0.998	0.002
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.000	0.998	0.002
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.000	0.998	0.002
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
K26.5 Chronic or unspecified with perforation	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
K26.0 Acute with haemorrhage	0.000	0.998	0.002
L25.9 Unspecified contact dermatitis, unspecified cause	0.002	0.998	0.000
S20.7 Multiple superficial injuries of thorax	0.000	0.998	0.002
S20.0 Contusion of breast	0.000	0.998	0.002
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.000	0.998	0.002
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.000	0.998	0.002
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.000	0.998	0.002
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.000	0.998	0.002
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.000	0.998	0.002
M46.22 Osteomyelitis of vertebra (Cervical region)	0.000	0.998	0.002
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.000	0.998	0.002
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.000	0.998	0.002
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.002	0.998	0.000
Y54.5 Other diuretics	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
M46.09 Spinal enthesopathy (Site unspecified)	0.000	0.998	0.002
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.07 Spinal enthesopathy (Lumbosacral region)	0.000	0.998	0.002
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.000	0.998	0.002
M46.04 Spinal enthesopathy (Thoracic region)	0.000	0.998	0.002
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.000	0.998	0.002
M46.02 Spinal enthesopathy (Cervical region)	0.000	0.998	0.002
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.000	0.998	0.002
K26.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.998	0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.000	0.998	0.002
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.47 Discitis, unspecified (Lumbosacral region)	0.000	0.998	0.002
M46.45 Discitis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M46.43 Discitis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M46.42 Discitis, unspecified (Cervical region)	0.000	0.998	0.002
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M46.40 Discitis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.002	0.998	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.998	0.002
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.000	0.998	0.002
D70 Agranulocytosis	0.002	0.998	0.000
M10.92 Gout, unspecified (Upper arm)	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.002	0.998	0.000
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.002	0.998	0.000
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.998	0.002
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.000	0.998	0.002
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.000	0.998	0.002
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.000	0.998	0.002
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.000	0.998	0.002
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.000	0.998	0.002
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.000	0.998	0.002
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.000	0.998	0.002
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.000	0.998	0.002
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.000	0.998	0.002
K26.1 Acute with perforation	0.000	0.998	0.002
Z42.9 Follow-up care involving plastic surgery, unspecified	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
K26.2 Acute with both haemorrhage and perforation	0.000	0.998	0.002
M31.6 Other giant cell arteritis	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.000	0.998	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
G61.1 Serum neuropathy	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.000	0.998	0.002
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.002	0.998	0.000
R00 Abnormalities of heart beat	0.000	0.998	0.002
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.998	0.002
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.998	0.002
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.998	0.002
S52.1 Fracture of upper end of radius	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.998	0.001
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
A87 Viral meningitis	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.998	0.002
M10.90 Gout, unspecified (Multiple sites)	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
D56 Thalassaemia	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.001	0.998	0.000
L25 Unspecified contact dermatitis	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D57 Sickle-cell disorders	0.001	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.998	0.001
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
M85.6 Other cyst of bone	0.000	0.998	0.002
N30.8 Other cystitis	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.000	0.998	0.001
Q60.5 Renal hypoplasia, unspecified	0.000	0.998	0.001
Q60.4 Renal hypoplasia, bilateral	0.000	0.998	0.001
Q60.3 Renal hypoplasia, unilateral	0.000	0.998	0.001
Q60.1 Renal agenesis, bilateral	0.000	0.998	0.001
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.002
B27.9 Infectious mononucleosis, unspecified	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.998	0.002
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.998	0.001
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.998	0.001
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.001
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.998	0.002
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.998	0.001
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.998	0.001
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.998	0.001
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.998	0.001
M85.68 Other cyst of bone (Other)	0.000	0.998	0.001
S52.11 Fracture of upper end of radius (open)	0.001	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
S32.2 Fracture of coccyx	0.000	0.998	0.001
T87.4 Infection of amputation stump	0.000	0.998	0.002
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.000	0.998	0.001
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.001	0.998	0.000
S22.20 Fracture of sternum (closed)	0.001	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
B44.9 Aspergillosis, unspecified	0.000	0.998	0.002
D72.1 Eosinophilia	0.001	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.998	0.001
D03 Melanoma in situ	0.002	0.998	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.998	0.002
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.998	0.002
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Y95 Nosocomial condition	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.001	0.998	0.000
A18.1 Tuberculosis of genito-urinary system	0.001	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.001	0.998	0.000
R23.3 Spontaneous ecchymoses	0.001	0.998	0.000
A18 Tuberculosis of other organs	0.001	0.998	0.000
X78 Intentional self-harm by sharp object	0.000	0.998	0.001
A87.8 Other viral meningitis	0.000	0.999	0.001
A87.1 Adenoviral meningitis	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
D13.2 Duodenum	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.999	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.999	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.999	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.999	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.999	0.000
G82.2 Paraplegia, unspecified	0.001	0.999	0.000
S32.1 Fracture of sacrum	0.000	0.999	0.001
S06.00 Concussion (without open intracranial wound)	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
D03.8 Melanoma in situ of other sites	0.001	0.999	0.000
D11.0 Parotid gland	0.000	0.999	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations