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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11608709
log Bayes Factor = 15.4681
Chromosome 12   position 99,302,859  (GRCh37) Explore rs11608709 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.991 0.009 0.000
E86 Volume depletion
0.990 0.010 0.000
F30-F39 Mood [affective] disorders
0.987 0.013 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.986 0.014 0.000
S80-S89 Injuries to the knee and lower leg
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.977 0.023 0.000
I71 Aortic aneurysm and dissection
0.969 0.031 0.000
E10 Insulin-dependent diabetes mellitus
0.967 0.033 0.000
I60-I69 Cerebrovascular diseases
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.954 0.046 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.949 0.051 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.949 0.051 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.948 0.052 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.947 0.053 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.946 0.054 0.000
F33 Recurrent depressive disorder
0.944 0.056 0.000
W00-W19 Falls
0.931 0.069 0.000
O60-O75 Complications of labour and delivery
0.930 0.070 0.000
E83 Disorders of mineral metabolism
0.930 0.070 0.000
I69 Sequelae of cerebrovascular disease
0.927 0.073 0.000
Chapter I Certain infectious and parasitic diseases
0.925 0.075 0.000
I51 Complications and ill-defined descriptions of heart disease
0.921 0.079 0.000
F41 Other anxiety disorders
0.910 0.090 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.906 0.094 0.000
S82 Fracture of lower leg, including ankle
0.905 0.095 0.000
R00 Abnormalities of heart beat
0.898 0.102 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.896 0.104 0.000
R00.2 Palpitations
0.895 0.105 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.892 0.108 0.000
T43.2 Other and unspecified antidepressants
0.888 0.112 0.000
I63 Cerebral infarction
0.887 0.113 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.887 0.113 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.885 0.115 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.879 0.121 0.000
G90-G99 Other disorders of the nervous system
0.875 0.125 0.000
I72 Other aneurysm
0.871 0.129 0.000
I51.8 Other ill-defined heart diseases
0.870 0.130 0.000
F10.3 Withdrawal state
0.869 0.131 0.000
F33.9 Recurrent depressive disorder, unspecified
0.868 0.132 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.866 0.134 0.000
E87.5 Hyperkalaemia
0.865 0.135 0.000
S81 Open wound of lower leg
0.864 0.136 0.000
F31 Bipolar affective disorder
0.863 0.137 0.000
Chapter XIV Diseases of the genitourinary system
0.863 0.137 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.862 0.138 0.000
F41.2 Mixed anxiety and depressive disorder
0.862 0.138 0.000
W19 Unspecified fall
0.862 0.138 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.860 0.140 0.000
S80 Superficial injury of lower leg
0.856 0.143 0.000
I05-I09 Chronic rheumatic heart diseases
0.854 0.146 0.000
F32 Depressive episode
0.854 0.146 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.853 0.147 0.000
Chapter XXII Codes for special purposes
0.849 0.151 0.000
I10-I15 Hypertensive diseases
0.847 0.153 0.000
I45 Other conduction disorders
0.847 0.153 0.000
R02 Gangrene, not elsewhere classified
0.842 0.158 0.000
E10.2 With renal complications
0.841 0.159 0.000
E10.9 Without complications
0.841 0.159 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.839 0.161 0.000
O70 Perineal laceration during delivery
0.839 0.161 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.839 0.161 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.838 0.162 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.838 0.162 0.000
F60-F69 Disorders of adult personality and behaviour
0.834 0.166 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.833 0.167 0.000
I63.9 Cerebral infarction, unspecified
0.832 0.168 0.000
S10-S19 Injuries to the neck
0.831 0.169 0.000
E10.3 With ophthalmic complications
0.829 0.171 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.827 0.173 0.000
I74 Arterial embolism and thrombosis
0.825 0.175 0.000
E87.6 Hypokalaemia
0.825 0.175 0.000
E10.5 With peripheral circulatory complications
0.824 0.176 0.000
R79 Other abnormal findings of blood chemistry
0.819 0.181 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.817 0.183 0.000
E20-E35 Disorders of other endocrine glands
0.816 0.184 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.816 0.184 0.000
N17-N19 Renal failure
0.815 0.185 0.000
S40-S49 Injuries to the shoulder and upper arm
0.811 0.188 0.000
I30 Acute pericarditis
0.811 0.189 0.000
S82.8 Fractures of other parts of lower leg
0.810 0.189 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.808 0.192 0.000
E87.2 Acidosis
0.806 0.194 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.801 0.199 0.000
I51.7 Cardiomegaly
0.801 0.199 0.000
F10.1 Harmful use
0.801 0.199 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.801 0.199 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.800 0.200 0.000
E83.5 Disorders of calcium metabolism
0.800 0.200 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.800 0.200 0.000
E10.4 With neurological complications
0.799 0.201 0.000
E11 Non-insulin-dependent diabetes mellitus
0.799 0.201 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.797 0.203 0.000
R45 Symptoms and signs involving emotional state
0.795 0.205 0.000
F10.2 Dependence syndrome
0.794 0.206 0.000
X60-X84 Intentional self-harm
0.792 0.208 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.792 0.208 0.000
E83.4 Disorders of magnesium metabolism
0.792 0.208 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.791 0.209 0.000
E50-E64 Other nutritional deficiencies
0.790 0.210 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.790 0.210 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.789 0.211 0.000
Chapter VIII Diseases of the ear and mastoid process
0.788 0.211 0.000
N19 Unspecified renal failure
0.787 0.213 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.785 0.215 0.000
I69.3 Sequelae of cerebral infarction
0.782 0.218 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.782 0.218 0.000
Chapter X Diseases of the respiratory system
0.781 0.219 0.000
F43 Reaction to severe stress, and adjustment disorders
0.780 0.220 0.000
G51 Facial nerve disorders
0.779 0.220 0.000
O72 Postpartum haemorrhage
0.777 0.223 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.776 0.224 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.776 0.224 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.776 0.224 0.000
S20-S29 Injuries to the thorax
0.774 0.226 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.774 0.226 0.000
B25-B34 Other viral diseases
0.773 0.226 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.770 0.230 0.000
O00-O08 Pregnancy with abortive outcome
0.768 0.231 0.000
A30-A49 Other bacterial diseases
0.768 0.232 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.766 0.234 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.762 0.238 0.000
F99-F99 Unspecified mental disorder
0.759 0.241 0.000
E87.7 Fluid overload
0.758 0.242 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.758 0.242 0.000
J95-J99 Other diseases of the respiratory system
0.757 0.243 0.000
S80.9 Superficial injury of lower leg, unspecified
0.756 0.244 0.000
F80-F89 Disorders of psychological development
0.752 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.752 0.248 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.750 0.250 0.000
I44 Atrioventricular and left bundle-branch block
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.251 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.748 0.252 0.000
W19.4 Street and highway
0.747 0.253 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.747 0.253 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.746 0.254 0.000
S90-S99 Injuries to the ankle and foot
0.745 0.255 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.744 0.256 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.744 0.256 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.743 0.257 0.000
B35-B49 Mycoses
0.743 0.257 0.000
I72.3 Aneurysm of iliac artery
0.743 0.257 0.000
J20-J22 Other acute lower respiratory infections
0.743 0.257 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.743 0.257 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.742 0.257 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
F31.9 Bipolar affective disorder, unspecified
0.742 0.258 0.000
I77 Other disorders of arteries and arterioles
0.742 0.258 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.741 0.259 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.740 0.260 0.000
G93 Other disorders of brain
0.740 0.260 0.000
G57 Mononeuropathies of lower limb
0.738 0.262 0.000
E83.3 Disorders of phosphorus metabolism
0.737 0.262 0.000
G70-G73 Diseases of myoneural junction and muscle
0.737 0.263 0.000
E10.1 With ketoacidosis
0.735 0.265 0.000
J98 Other respiratory disorders
0.732 0.268 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.732 0.268 0.000
I70 Atherosclerosis
0.731 0.269 0.000
S89 Other and unspecified injuries of lower leg
0.731 0.269 0.000
W19.9 Unspecified place
0.730 0.270 0.000
Y52 Agents primarily affecting the cardiovascular system
0.730 0.270 0.000
I45.1 Other and unspecified right bundle-branch block
0.728 0.271 0.000
B95-B98 Bacterial, viral and other infectious agents
0.727 0.273 0.000
S70-S79 Injuries to the hip and thigh
0.726 0.274 0.000
E88 Other metabolic disorders
0.726 0.274 0.000
N60-N64 Disorders of breast
0.725 0.274 0.000
N25-N29 Other disorders of kidney and ureter
0.725 0.275 0.000
R04 Haemorrhage from respiratory passages
0.724 0.276 0.000
R41.0 Disorientation, unspecified
0.723 0.277 0.000
S81.8 Open wound of other parts of lower leg
0.723 0.277 0.000
W10 Fall on and from stairs and steps
0.722 0.278 0.000
G51.0 Bell's palsy
0.722 0.278 0.000
O70.1 Second degree perineal laceration during delivery
0.722 0.278 0.000
Chapter VII Diseases of the eye and adnexa
0.721 0.279 0.000
I10 Essential (primary) hypertension
0.720 0.280 0.000
S82.3 Fracture of lower end of tibia
0.719 0.281 0.000
R45.1 Restlessness and agitation
0.719 0.281 0.000
I78 Diseases of capillaries
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
T39.0 Salicylates
0.717 0.283 0.000
S82.1 Fracture of upper end of tibia
0.716 0.283 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.716 0.284 0.000
S81.0 Open wound of knee
0.716 0.284 0.000
G35 Multiple sclerosis
0.716 0.284 0.000
F03 Unspecified dementia
0.716 0.284 0.000
J22 Unspecified acute lower respiratory infection
0.715 0.285 0.000
F60 Specific personality disorders
0.715 0.285 0.000
F32.0 Mild depressive episode
0.715 0.285 0.000
F17.1 Harmful use
0.715 0.285 0.000
I60 Subarachnoid haemorrhage
0.714 0.286 0.000
W08 Fall involving other furniture
0.714 0.286 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.288 0.000
S82.6 Fracture of lateral malleolus
0.711 0.289 0.000
I73 Other peripheral vascular diseases
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.710 0.290 0.000
E87.4 Mixed disorder of acid-base balance
0.710 0.290 0.000
E87.3 Alkalosis
0.710 0.290 0.000
E87.0 Hyperosmolality and hypernatraemia
0.710 0.290 0.000
T42.4 Benzodiazepines
0.710 0.290 0.000
N00-N08 Glomerular diseases
0.710 0.290 0.000
N30-N39 Other diseases of urinary system
0.710 0.290 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.709 0.291 0.000
I30.9 Acute pericarditis, unspecified
0.708 0.292 0.000
W13 Fall from, out of or through building or structure
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
F38 Other mood [affective] disorders
0.708 0.292 0.000
F34 Persistent mood [affective] disorders
0.708 0.292 0.000
F30 Manic episode
0.708 0.292 0.000
F39 Unspecified mood [affective] disorder
0.708 0.292 0.000
O70.0 First degree perineal laceration during delivery
0.707 0.293 0.000
O85-O92 Complications predominantly related to the puerperium
0.707 0.293 0.000
S88 Traumatic amputation of lower leg
0.705 0.295 0.000
S87 Crushing injury of lower leg
0.705 0.295 0.000
S86 Injury of muscle and tendon at lower leg level
0.705 0.295 0.000
S85 Injury of blood vessels at lower leg level
0.705 0.295 0.000
S84 Injury of nerves at lower leg level
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
I72.0 Aneurysm of carotid artery
0.703 0.297 0.000
D80-D89 Certain disorders involving the immune mechanism
0.703 0.297 0.000
I38 Endocarditis, valve unspecified
0.702 0.298 0.000
E13 Other specified diabetes mellitus
0.702 0.298 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.701 0.299 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.701 0.299 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.701 0.299 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.701 0.299 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.701 0.299 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.701 0.299 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.701 0.299 0.000
F11 Mental and behavioural disorders due to use of opioids
0.701 0.299 0.000
J98.1 Pulmonary collapse
0.698 0.302 0.000
I34 Nonrheumatic mitral valve disorders
0.695 0.305 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.694 0.305 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.694 0.305 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.694 0.305 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.694 0.305 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.694 0.305 0.000
I71.0 Dissection of aorta [any part]
0.694 0.305 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
E10.8 With unspecified complications
0.694 0.306 0.000
E10.7 With multiple complications
0.694 0.306 0.000
E10.6 With other specified complications
0.694 0.306 0.000
E10.0 With coma
0.694 0.306 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.308 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.308 0.000
S82.5 Fracture of medial malleolus
0.692 0.308 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.691 0.309 0.000
N64 Other disorders of breast
0.691 0.309 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.688 0.311 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.688 0.312 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.687 0.313 0.000
F32.1 Moderate depressive episode
0.687 0.313 0.000
V10-V19 Pedal cyclist injured in transport accident
0.687 0.313 0.000
O80-O84 Delivery
0.686 0.314 0.000
G96 Other disorders of central nervous system
0.686 0.314 0.000
F41.9 Anxiety disorder, unspecified
0.685 0.315 0.000
F10.0 Acute intoxication
0.685 0.315 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.684 0.316 0.000
I52 Other heart disorders in diseases classified elsewhere
0.684 0.316 0.000
I48 Atrial fibrillation and flutter
0.684 0.316 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.684 0.316 0.000
I41 Myocarditis in diseases classified elsewhere
0.684 0.316 0.000
I40 Acute myocarditis
0.684 0.316 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.684 0.316 0.000
I37 Pulmonary valve disorders
0.684 0.316 0.000
I36 Nonrheumatic tricuspid valve disorders
0.684 0.316 0.000
I33 Acute and subacute endocarditis
0.684 0.316 0.000
I32 Pericarditis in diseases classified elsewhere
0.684 0.316 0.000
I05 Rheumatic mitral valve diseases
0.684 0.316 0.000
I08 Multiple valve diseases
0.681 0.318 0.000
T43.9 Psychotropic drug, unspecified
0.680 0.320 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.680 0.320 0.000
T43.6 Psychostimulants with abuse potential
0.680 0.320 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.680 0.320 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.680 0.320 0.000
F48 Other neurotic disorders
0.679 0.320 0.000
F44 Dissociative [conversion] disorders
0.679 0.320 0.000
F42 Obsessive-compulsive disorder
0.679 0.320 0.000
G20-G26 Extrapyramidal and movement disorders
0.679 0.320 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.679 0.321 0.000
F10.9 Unspecified mental and behavioural disorder
0.678 0.322 0.000
F10.8 Other mental and behavioural disorders
0.678 0.322 0.000
F10.7 Residual and late-onset psychotic disorder
0.678 0.322 0.000
F10.6 Amnesic syndrome
0.678 0.322 0.000
F10.5 Psychotic disorder
0.678 0.322 0.000
F10.4 Withdrawal state with delirium
0.678 0.322 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.677 0.323 0.000
F33.8 Other recurrent depressive disorders
0.677 0.323 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.677 0.323 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.677 0.323 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.677 0.323 0.000
S50-S59 Injuries to the elbow and forearm
0.676 0.323 0.000
E11.4 With neurological complications
0.676 0.324 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.675 0.325 0.000
W07 Fall involving chair
0.673 0.326 0.000
I44.0 Atrioventricular block, first degree
0.673 0.327 0.000
W06 Fall involving bed
0.673 0.327 0.000
H90-H95 Other disorders of ear
0.672 0.328 0.000
E83.1 Disorders of iron metabolism
0.671 0.329 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.671 0.329 0.000
S10 Superficial injury of neck
0.670 0.330 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.670 0.330 0.000
S40 Superficial injury of shoulder and upper arm
0.669 0.331 0.000
W18 Other fall on same level
0.668 0.332 0.000
W17 Other fall from one level to another
0.668 0.332 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.668 0.332 0.000
W15 Fall from cliff
0.668 0.332 0.000
W14 Fall from tree
0.668 0.332 0.000
W12 Fall on and from scaffolding
0.668 0.332 0.000
W11 Fall on and from ladder
0.668 0.332 0.000
W09 Fall involving playground equipment
0.668 0.332 0.000
W05 Fall involving wheelchair
0.668 0.332 0.000
W04 Fall while being carried or supported by other persons
0.668 0.332 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.668 0.332 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.668 0.332 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.668 0.332 0.000
W00 Fall on same level involving ice and snow
0.668 0.332 0.000
A00-A09 Intestinal infectious diseases
0.668 0.332 0.000
O74 Complications of anaesthesia during labour and delivery
0.667 0.333 0.000
O73 Retained placenta and membranes, without haemorrhage
0.667 0.333 0.000
O71 Other obstetric trauma
0.667 0.333 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.667 0.333 0.000
O66 Other obstructed labour
0.667 0.333 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.667 0.333 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.667 0.333 0.000
O62 Abnormalities of forces of labour
0.667 0.333 0.000
O61 Failed induction of labour
0.667 0.333 0.000
O60 Preterm delivery
0.667 0.333 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.667 0.333 0.000
E83.8 Other disorders of mineral metabolism
0.667 0.333 0.000
E83.2 Disorders of zinc metabolism
0.667 0.333 0.000
E83.0 Disorders of copper metabolism
0.667 0.333 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
Y45.0 Opioids and related analgesics
0.665 0.335 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.665 0.335 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.665 0.335 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.665 0.335 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.665 0.335 0.000
B34 Viral infection of unspecified site
0.665 0.335 0.000
W19.2 School, other institution and public administrative area
0.664 0.336 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.664 0.336 0.000
I46 Cardiac arrest
0.664 0.336 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.664 0.336 0.000
B99-B99 Other infectious diseases
0.663 0.336 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.663 0.336 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.663 0.336 0.000
B65-B83 Helminthiases
0.663 0.336 0.000
B50-B64 Protozoal diseases
0.663 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.663 0.336 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.663 0.336 0.000
A80-A89 Viral infections of the central nervous system
0.663 0.336 0.000
A75-A79 Rickettsioses
0.663 0.336 0.000
A70-A74 Other diseases caused by chlamydiae
0.663 0.336 0.000
A65-A69 Other spirochaetal diseases
0.663 0.336 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.663 0.336 0.000
A20-A28 Certain zoonotic bacterial diseases
0.663 0.336 0.000
A15-A19 Tuberculosis
0.663 0.336 0.000
R01 Cardiac murmurs and other cardiac sounds
0.663 0.337 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.663 0.337 0.000
E23 Hypofunction and other disorders of pituitary gland
0.662 0.338 0.000
S00-S09 Injuries to the head
0.662 0.338 0.000
R50-R69 General symptoms and signs
0.662 0.338 0.000
R40 Somnolence, stupor and coma
0.661 0.339 0.000
I51.6 Cardiovascular disease, unspecified
0.660 0.339 0.000
I51.5 Myocardial degeneration
0.660 0.339 0.000
I51.4 Myocarditis, unspecified
0.660 0.339 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.660 0.339 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.660 0.339 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.660 0.339 0.000
I51.0 Cardiac septal defect, acquired
0.660 0.339 0.000
I95 Hypotension
0.661 0.339 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.660 0.340 0.000
I51.9 Heart disease, unspecified
0.660 0.340 0.000
I45.5 Other specified heart block
0.660 0.340 0.000
F20 Schizophrenia
0.658 0.342 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.655 0.345 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.655 0.345 0.000
R63 Symptoms and signs concerning food and fluid intake
0.654 0.346 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.654 0.346 0.000
S19 Other and unspecified injuries of neck
0.654 0.346 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.654 0.346 0.000
E11.2 With renal complications
0.653 0.347 0.000
F41.8 Other specified anxiety disorders
0.652 0.347 0.000
F41.3 Other mixed anxiety disorders
0.652 0.347 0.000
F41.1 Generalised anxiety disorder
0.652 0.347 0.000
F05.9 Delirium, unspecified
0.652 0.348 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.652 0.348 0.000
S20 Superficial injury of thorax
0.652 0.348 0.000
Y40 Systemic antibiotics
0.652 0.348 0.000
N36 Other disorders of urethra
0.652 0.348 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.650 0.350 0.000
G57.6 Lesion of plantar nerve
0.650 0.350 0.000
S82.9 Fracture of lower leg, part unspecified
0.649 0.351 0.000
S82.7 Multiple fractures of lower leg
0.649 0.351 0.000
G81 Hemiplegia
0.649 0.351 0.000
R42 Dizziness and giddiness
0.648 0.352 0.000
I45.6 Preexcitation syndrome
0.648 0.352 0.000
E53 Deficiency of other B group vitamins
0.648 0.352 0.000
I07 Rheumatic tricuspid valve diseases
0.647 0.353 0.000
I62 Other nontraumatic intracranial haemorrhage
0.647 0.353 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.647 0.353 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.646 0.354 0.000
F17.2 Dependence syndrome
0.644 0.356 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.644 0.356 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.644 0.356 0.000
O20 Haemorrhage in early pregnancy
0.644 0.356 0.000
G60 Hereditary and idiopathic neuropathy
0.644 0.356 0.000
I63.8 Other cerebral infarction
0.643 0.357 0.000
R46 Symptoms and signs involving appearance and behaviour
0.642 0.358 0.000
R43 Disturbances of smell and taste
0.642 0.358 0.000
T51 Toxic effect of alcohol
0.642 0.358 0.000
R74 Abnormal serum enzyme levels
0.641 0.358 0.000
E29 Testicular dysfunction
0.641 0.359 0.000
T92 Sequelae of injuries of upper limb
0.641 0.359 0.000
R63.4 Abnormal weight loss
0.639 0.361 0.000
R21 Rash and other nonspecific skin eruption
0.639 0.361 0.000
F43.1 Posttraumatic stress disorder
0.639 0.361 0.000
B15-B19 Viral hepatitis
0.638 0.362 0.000
R00.0 Tachycardia, unspecified
0.638 0.362 0.000
S80.8 Other superficial injuries of lower leg
0.637 0.362 0.000
R23 Other skin changes
0.637 0.363 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.637 0.363 0.000
G50 Disorders of trigeminal nerve
0.637 0.363 0.000
I31 Other diseases of pericardium
0.636 0.364 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.636 0.364 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.636 0.364 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.636 0.364 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.636 0.364 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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