TreeWAS – Variant ID: rs116256340

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
M20 Acquired deformities of fingers and toes	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.997	0.003
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.995	0.005
Chapter VI Diseases of the nervous system	0.991	0.009
M20.4 Other hammer toe(s) (acquired)	0.991	0.009
M20.1 Hallux valgus (acquired)	0.990	0.010
G40-G47 Episodic and paroxysmal disorders	0.988	0.012
G40 Epilepsy	0.986	0.014
C51-C58 Malignant neoplasms of female genital organs	0.982	0.018
C77.1 Intrathoracic lymph nodes	0.979	0.021
M20.5 Other deformities of toe(s) (acquired)	0.977	0.023
C77.9 Lymph node, unspecified	0.976	0.024
G40.9 Epilepsy, unspecified	0.976	0.024
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.972	0.028
Chapter XX External causes of morbidity and mortality	0.970	0.030
Chapter VIII Diseases of the ear and mastoid process	0.970	0.030
Chapter V Mental and behavioural disorders	0.963	0.037
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.962	0.038
C15-C26 Malignant neoplasms of digestive organs	0.959	0.041
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.958	0.042
M24 Other specific joint derangements	0.956	0.044
M20.2 Hallux rigidus	0.955	0.045
Chapter VII Diseases of the eye and adnexa	0.947	0.053
F30-F39 Mood [affective] disorders	0.946	0.054
S40-S49 Injuries to the shoulder and upper arm	0.942	0.058
T84.1 Mechanical complication of internal fixation device of bones of limb	0.941	0.059
S90-S99 Injuries to the ankle and foot	0.935	0.065
F32 Depressive episode	0.930	0.070
Q60-Q64 Congenital malformations of the urinary system	0.929	0.071
M45-M49 Spondylopathies	0.928	0.072
H53-H54 Visual disturbances and blindness	0.927	0.073
M35 Other systemic involvement of connective tissue	0.926	0.074
C56 Malignant neoplasm of ovary	0.918	0.082
G45 Transient cerebral ischaemic attacks and related syndromes	0.915	0.085
H65-H75 Diseases of middle ear and mastoid	0.911	0.089
H53 Visual disturbances	0.910	0.090
M20.6 Acquired deformity of toe(s), unspecified	0.897	0.103
Q61 Cystic kidney disease	0.892	0.108
F32.1 Moderate depressive episode	0.891	0.109
G45.9 Transient cerebral ischaemic attack, unspecified	0.890	0.110
D37-D48 Neoplasms of uncertain or unknown behaviour	0.882	0.118
W00-W19 Falls	0.880	0.120
C18 Malignant neoplasm of colon	0.871	0.129
M47 Spondylosis	0.868	0.132
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.868	0.132
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.867	0.133
T88 Other complications of surgical and medical care, not elsewhere classified	0.867	0.133
T20-T25 Burns and corrosions of external body surface, specified by site	0.866	0.134
C77.2 Intra-abdominal lymph nodes	0.866	0.134
M35.0 Sicca syndrome [Sjogren]	0.866	0.134
C55 Malignant neoplasm of uterus, part unspecified	0.859	0.141
M60-M63 Disorders of muscles	0.857	0.143
Q61.3 Polycystic kidney, unspecified	0.853	0.147
H53.0 Amblyopia ex anopsia	0.851	0.149
H71 Cholesteatoma of middle ear	0.851	0.149
S41 Open wound of shoulder and upper arm	0.845	0.155
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.839	0.161
F40-F48 Neurotic, stress-related and somatoform disorders	0.836	0.164
Chapter I Certain infectious and parasitic diseases	0.834	0.166
M46 Other inflammatory spondylopathies	0.828	0.172
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.827	0.173
M24.8 Other specific joint derangements, not elsewhere classified	0.824	0.176
F60-F69 Disorders of adult personality and behaviour	0.818	0.182
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.816	0.184
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.815	0.185
F32.3 Severe depressive episode with psychotic symptoms	0.813	0.187
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.812	0.188
S90 Superficial injury of ankle and foot	0.812	0.188
T84.0 Mechanical complication of internal joint prosthesis	0.808	0.192
C76 Malignant neoplasm of other and ill-defined sites	0.807	0.193
T84.3 Mechanical complication of other bone devices, implants and grafts	0.807	0.193
C77.8 Lymph nodes of multiple regions	0.807	0.193
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.807	0.193
C77.4 Inguinal and lower limb lymph nodes	0.807	0.193
C20 Malignant neoplasm of rectum	0.804	0.196
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.803	0.197
G80-G83 Cerebral palsy and other paralytic syndromes	0.799	0.201
C53 Malignant neoplasm of cervix uteri	0.796	0.204
H30-H36 Disorders of choroid and retina	0.795	0.205
G70-G73 Diseases of myoneural junction and muscle	0.795	0.205
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.793	0.207
M47.8 Other spondylosis	0.793	0.207
W20-W49 Exposure to inanimate mechanical forces	0.791	0.209
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.791	0.209
C54 Malignant neoplasm of corpus uteri	0.790	0.210
W19 Unspecified fall	0.790	0.210
G00-G09 Inflammatory diseases of the central nervous system	0.788	0.212
H80-H83 Diseases of inner ear	0.786	0.214
S60-S69 Injuries to the wrist and hand	0.786	0.214
F33 Recurrent depressive disorder	0.785	0.214
M22 Disorders of patella	0.785	0.215
F39 Unspecified mood [affective] disorder	0.785	0.215
H90-H95 Other disorders of ear	0.784	0.216
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.783	0.216
C18.1 Appendix	0.783	0.217
H74 Other disorders of middle ear and mastoid	0.780	0.220
Q61.2 Polycystic kidney, adult type	0.779	0.221
M24.5 Contracture of joint	0.779	0.221
M24.1 Other articular cartilage disorders	0.778	0.222
C21 Malignant neoplasm of anus and anal canal	0.778	0.222
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.777	0.223
M80-M85 Disorders of bone density and structure	0.774	0.226
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.772	0.228
Y00-Y09 Assault	0.771	0.229
M24.2 Disorder of ligament	0.769	0.231
S99 Other and unspecified injuries of ankle and foot	0.768	0.232
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.768	0.232
T15-T19 Effects of foreign body entering through natural orifice	0.765	0.235
H53.9 Visual disturbance, unspecified	0.765	0.235
M65-M68 Disorders of synovium and tendon	0.764	0.236
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.763	0.237
S49 Other and unspecified injuries of shoulder and upper arm	0.762	0.238
W50-W64 Exposure to animate mechanical forces	0.762	0.238
M33 Dermatopolymyositis	0.757	0.243
H35 Other retinal disorders	0.757	0.243
M46.9 Inflammatory spondylopathy, unspecified	0.756	0.244
C15 Malignant neoplasm of oesophagus	0.756	0.244
F40 Phobic anxiety disorders	0.756	0.244
S92 Fracture of foot, except ankle	0.755	0.245
H60-H62 Diseases of external ear	0.755	0.245
M62 Other disorders of muscle	0.754	0.245
H53.8 Other visual disturbances	0.753	0.247
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.752	0.248
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.751	0.249
T88.4 Failed or difficult intubation	0.746	0.254
T80 Complications following infusion, transfusion and therapeutic injection	0.746	0.254
X58-X59 Accidental exposure to other and unspecified factors	0.746	0.254
F32.2 Severe depressive episode without psychotic symptoms	0.746	0.254
C57 Malignant neoplasm of other and unspecified female genital organs	0.743	0.257
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.743	0.257
C50-C50 Malignant neoplasm of breast	0.742	0.258
S50-S59 Injuries to the elbow and forearm	0.740	0.260
X50-X57 Overexertion, travel and privation	0.739	0.261
T00-T07 Injuries involving multiple body regions	0.739	0.261
S42 Fracture of shoulder and upper arm	0.738	0.262
Q63 Other congenital malformations of kidney	0.737	0.263
G50-G59 Nerve, nerve root and plexus disorders	0.736	0.264
B95-B98 Bacterial, viral and other infectious agents	0.736	0.264
H72 Perforation of tympanic membrane	0.736	0.264
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.736	0.264
C23 Malignant neoplasm of gallbladder	0.735	0.265
V10-V19 Pedal cyclist injured in transport accident	0.733	0.267
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.732	0.268
M47.9 Spondylosis, unspecified	0.732	0.268
S66 Injury of muscle and tendon at wrist and hand level	0.731	0.269
V20-V29 Motorcycle rider injured in transport accident	0.731	0.269
Y52 Agents primarily affecting the cardiovascular system	0.730	0.270
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.729	0.271
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.729	0.271
G44 Other headache syndromes	0.727	0.273
S80-S89 Injuries to the knee and lower leg	0.727	0.273
H53.1 Subjective visual disturbances	0.726	0.274
S41.1 Open wound of upper arm	0.726	0.274
S00-S09 Injuries to the head	0.726	0.274
T83.1 Mechanical complication of other urinary devices and implants	0.725	0.275
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.725	0.275
C16 Malignant neoplasm of stomach	0.724	0.276
Chapter X Diseases of the respiratory system	0.724	0.276
Q38-Q45 Other congenital malformations of the digestive system	0.723	0.277
J30-J39 Other diseases of upper respiratory tract	0.722	0.278
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.719	0.281
G40.8 Other epilepsy	0.719	0.281
M24.0 Loose body in joint	0.718	0.282
T87 Complications peculiar to reattachment and amputation	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.283
S70-S79 Injuries to the hip and thigh	0.716	0.284
C18.3 Hepatic flexure	0.716	0.284
V40-V49 Car occupant injured in transport accident	0.716	0.284
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.716	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
M20.3 Other deformity of hallux (acquired)	0.714	0.285
H35.0 Background retinopathy and retinal vascular changes	0.714	0.286
F60 Specific personality disorders	0.714	0.286
Q20-Q28 Congenital malformations of the circulatory system	0.713	0.286
Chapter XII Diseases of the skin and subcutaneous tissue	0.713	0.287
C18.2 Ascending colon	0.713	0.287
T88.7 Unspecified adverse effect of drug or medicament	0.712	0.287
C80 Malignant neoplasm without specification of site	0.710	0.290
F32.9 Depressive episode, unspecified	0.710	0.290
H52 Disorders of refraction and accommodation	0.710	0.290
X40-X49 Accidental poisoning by and exposure to noxious substances	0.709	0.291
G46 Vascular syndromes of brain in cerebrovascular diseases	0.708	0.291
H54 Blindness and low vision	0.708	0.292
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.708	0.292
C17 Malignant neoplasm of small intestine	0.707	0.293
H53.2 Diplopia	0.707	0.293
G40.7 Petit mal, unspecified, without grand mal seizures	0.707	0.293
G40.5 Special epileptic syndromes	0.707	0.293
G40.4 Other generalised epilepsy and epileptic syndromes	0.707	0.293
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.707	0.293
M24.4 Recurrent dislocation and subluxation of joint	0.706	0.293
C79 Secondary malignant neoplasm of other sites	0.706	0.294
S41.0 Open wound of shoulder	0.705	0.295
C58 Malignant neoplasm of placenta	0.704	0.296
C52 Malignant neoplasm of vagina	0.704	0.296
J32 Chronic sinusitis	0.704	0.296
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.703	0.297
T23 Burn and corrosion of wrist and hand	0.702	0.298
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.701	0.299
M91-M94 Chondropathies	0.701	0.299
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.701	0.299
D48.7 Other specified sites	0.700	0.300
V80-V89 Other land transport accidents	0.700	0.300
T21 Burn and corrosion of trunk	0.700	0.300
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.699	0.301
Chapter IV Endocrine, nutritional and metabolic diseases	0.699	0.301
C19 Malignant neoplasm of rectosigmoid junction	0.698	0.302
S90.9 Superficial injury of ankle and foot, unspecified	0.697	0.303
M35.3 Polymyalgia rheumatica	0.697	0.303
Y35-Y36 Legal intervention and operations of war	0.696	0.304
Y10-Y34 Event of undetermined intent	0.696	0.304
X85-X99 Assault	0.696	0.304
X30-X39 Exposure to forces of nature	0.696	0.304
X10-X19 Contact with heat and hot substances	0.696	0.304
X00-X09 Exposure to smoke, fire and flames	0.696	0.304
W75-W84 Other accidental threats to breathing	0.696	0.304
W65-W74 Accidental drowning and submersion	0.696	0.304
V98-V99 Other and unspecified transport accidents	0.696	0.304
V95-V97 Air and space transport accidents	0.696	0.304
V90-V94 Water transport accidents	0.696	0.304
V70-V79 Bus occupant injured in transport accident	0.696	0.304
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.696	0.304
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.696	0.304
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.696	0.304
V01-V09 Pedestrian injured in transport accident	0.696	0.304
Q60 Renal agenesis and other reduction defects of kidney	0.693	0.307
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.692	0.308
M34 Systemic sclerosis	0.691	0.308
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.691	0.309
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.691	0.309
F70-F79 Mental retardation	0.691	0.309
W18 Other fall on same level	0.690	0.310
M47.89 Other spondylosis (Site unspecified)	0.690	0.310
C77.0 Lymph nodes of head, face and neck	0.690	0.310
T66-T78 Other and unspecified effects of external causes	0.690	0.310
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.690	0.310
H69 Other disorders of Eustachian tube	0.690	0.310
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.690	0.310
Q35-Q37 Cleft lip and cleft palate	0.690	0.310
Q30-Q34 Congenital malformations of the respiratory system	0.690	0.310
Q80-Q89 Other congenital malformations	0.690	0.310
S46 Injury of muscle and tendon at shoulder and upper arm level	0.689	0.311
J32.9 Chronic sinusitis, unspecified	0.688	0.312
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.687	0.312
C18.6 Descending colon	0.687	0.313
B97 Viral agents as the cause of diseases classified to other chapters	0.687	0.313
M24.9 Joint derangement, unspecified	0.685	0.315
M24.7 Protrusio acetabuli	0.685	0.315
M24.6 Ankylosis of joint	0.685	0.315
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.685	0.315
Y46 Antiepileptics and anti-Parkinsonism drugs	0.685	0.315
S91 Open wound of ankle and foot	0.684	0.316
M00-M03 Infectious arthropathies	0.684	0.316
G54 Nerve root and plexus disorders	0.684	0.316
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.682	0.318
A80-A89 Viral infections of the central nervous system	0.681	0.319
M62.8 Other specified disorders of muscle	0.681	0.319
C51 Malignant neoplasm of vulva	0.680	0.320
X60-X84 Intentional self-harm	0.680	0.320
C49 Malignant neoplasm of other connective and soft tissue	0.680	0.320
T79-T79 Certain early complications of trauma	0.679	0.320
X20-X29 Contact with venomous animals and plants	0.679	0.320
S20-S29 Injuries to the thorax	0.679	0.321
F38 Other mood [affective] disorders	0.678	0.321
F34 Persistent mood [affective] disorders	0.678	0.321
F30 Manic episode	0.678	0.321
L60-L75 Disorders of skin appendages	0.678	0.322
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.676	0.324
S48 Traumatic amputation of shoulder and upper arm	0.675	0.324
S45 Injury of blood vessels at shoulder and upper arm level	0.675	0.324
S44 Injury of nerves at shoulder and upper arm level	0.675	0.324
S47 Crushing injury of shoulder and upper arm	0.675	0.324
J31.0 Chronic rhinitis	0.675	0.325
H35.4 Peripheral retinal degeneration	0.674	0.326
G43 Migraine	0.673	0.327
T09 Other injuries of spine and trunk, level unspecified	0.673	0.327
W19.1 Residential institution	0.673	0.327
Y51 Drugs primarily affecting the autonomic nervous system	0.673	0.327
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.673	0.327
M47.85 Other spondylosis (Thoracolumbar region)	0.672	0.328
C76.3 Pelvis	0.672	0.328
G90-G99 Other disorders of the nervous system	0.671	0.328
S98 Traumatic amputation of ankle and foot	0.671	0.329
S97 Crushing injury of ankle and foot	0.671	0.329
S96 Injury of muscle and tendon at ankle and foot level	0.671	0.329
S95 Injury of blood vessels at ankle and foot level	0.671	0.329
S94 Injury of nerves at ankle and foot level	0.671	0.329
G41 Status epilepticus	0.671	0.329
H18 Other disorders of cornea	0.670	0.330
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.669	0.331
H46-H48 Disorders of optic nerve and visual pathways	0.669	0.331
F80-F89 Disorders of psychological development	0.669	0.331
F40.2 Specific (isolated) phobias	0.669	0.331
C73 Malignant neoplasm of thyroid gland	0.669	0.331
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.668	0.331
F32.8 Other depressive episodes	0.667	0.333
S40 Superficial injury of shoulder and upper arm	0.666	0.333
Q64 Other congenital malformations of urinary system	0.666	0.334
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.666	0.334
M49 Spondylopathies in diseases classified elsewhere	0.666	0.334
M31 Other necrotising vasculopathies	0.665	0.335
M22.8 Other disorders of patella	0.664	0.336
C18.4 Transverse colon	0.664	0.336
M35.9 Systemic involvement of connective tissue, unspecified	0.664	0.336
M35.8 Other specified systemic involvement of connective tissue	0.664	0.336
M35.7 Hypermobility syndrome	0.664	0.336
M35.6 Relapsing panniculitis [Weber-Christian]	0.664	0.336
M35.5 Multifocal fibrosclerosis	0.664	0.336
M35.4 Diffuse (eosinophilic) fasciitis	0.664	0.336
M35.2 Behcet's disease	0.664	0.336
M35.1 Other overlap syndromes	0.664	0.336
W06 Fall involving bed	0.664	0.336
W08 Fall involving other furniture	0.663	0.337
C53.9 Cervix uteri, unspecified	0.663	0.337
H16 Keratitis	0.662	0.338
Q50-Q56 Congenital malformations of genital organs	0.660	0.340
H21 Other disorders of iris and ciliary body	0.660	0.340
F33.1 Recurrent depressive disorder, current episode moderate	0.660	0.340
C71 Malignant neoplasm of brain	0.659	0.340
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.659	0.341
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.659	0.341
Q00-Q07 Congenital malformations of the nervous system	0.658	0.341
C26 Malignant neoplasm of other and ill-defined digestive organs	0.658	0.342
T86 Failure and rejection of transplanted organs and tissues	0.658	0.342
S10-S19 Injuries to the neck	0.658	0.342
H55-H59 Other disorders of eye and adnexa	0.657	0.343
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.657	0.343
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.656	0.344
G45.2 Multiple and bilateral precerebral artery syndromes	0.656	0.344
G45.1 Carotid artery syndrome (hemispheric)	0.656	0.344
G45.0 Vertebro-basilar artery syndrome	0.656	0.344
M47.2 Other spondylosis with radiculopathy	0.656	0.344
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.655	0.345
H52.1 Myopia	0.654	0.346
Y44 Agents primarily affecting blood constituents	0.654	0.346
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.653	0.347
H70 Mastoiditis and related conditions	0.653	0.347
H68 Eustachian salpingitis and obstruction	0.653	0.347
H67 Otitis media in diseases classified elsewhere	0.653	0.347
H53.6 Night blindness	0.653	0.347
H53.5 Colour vision deficiencies	0.653	0.347
H53.3 Other disorders of binocular vision	0.653	0.347
M24.56 Contracture of joint (Lower leg)	0.653	0.347
W19.9 Unspecified place	0.652	0.348
F33.9 Recurrent depressive disorder, unspecified	0.652	0.348
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.652	0.348
C54.1 Endometrium	0.652	0.348
S99.9 Unspecified injury of ankle and foot	0.648	0.352
Chapter XXII Codes for special purposes	0.648	0.352
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.648	0.352
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.647	0.353
H43-H45 Disorders of vitreous body and globe	0.647	0.353
C18.9 Colon, unspecified	0.647	0.353
G81 Hemiplegia	0.646	0.354
B20-B24 Human immunodeficiency virus [HIV] disease	0.645	0.355
H74.8 Other specified disorders of middle ear and mastoid	0.645	0.355
H66 Suppurative and unspecified otitis media	0.643	0.356
S66.8 Injury of other muscles and tendons at wrist and hand level	0.643	0.357
B99-B99 Other infectious diseases	0.642	0.357
W10 Fall on and from stairs and steps	0.642	0.357
W19.4 Street and highway	0.642	0.358
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.642	0.358
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.641	0.358
M47.87 Other spondylosis (Lumbosacral region)	0.641	0.359
W22 Striking against or struck by other objects	0.641	0.359
C02 Malignant neoplasm of other and unspecified parts of tongue	0.641	0.359
D48.5 Skin	0.640	0.360
Q61.9 Cystic kidney disease, unspecified	0.640	0.360
Q61.8 Other cystic kidney diseases	0.640	0.360
Q61.5 Medullary cystic kidney	0.640	0.360
Q61.4 Renal dysplasia	0.640	0.360
Q61.1 Polycystic kidney, infantile type	0.640	0.360
H91 Other hearing loss	0.639	0.361
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.639	0.361
F32.0 Mild depressive episode	0.636	0.363
H53.4 Visual field defects	0.636	0.363
M24.23 Disorder of ligament (Forearm)	0.635	0.364
S90.8 Other superficial injuries of ankle and foot	0.635	0.365
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.634	0.366
M24.16 Other articular cartilage disorders (Lower leg)	0.633	0.367
M22.4 Chondromalacia patellae	0.633	0.367
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.632	0.368
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.632	0.368
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.632	0.368
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.632	0.368
S49.9 Unspecified injury of shoulder and upper arm	0.632	0.368
L72 Follicular cysts of skin and subcutaneous tissue	0.632	0.368
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.632	0.368
M65 Synovitis and tenosynovitis	0.632	0.368
Y49 Psychotropic drugs, not elsewhere classified	0.631	0.369
W16 Diving or jumping into water causing injury other than drowning or submersion	0.631	0.369
W15 Fall from cliff	0.631	0.369
W14 Fall from tree	0.631	0.369
W12 Fall on and from scaffolding	0.631	0.369
W11 Fall on and from ladder	0.631	0.369
W09 Fall involving playground equipment	0.631	0.369
W05 Fall involving wheelchair	0.631	0.369
W04 Fall while being carried or supported by other persons	0.631	0.369
W03 Other fall on same level due to collision with, or pushing by, another person	0.631	0.369
W01 Fall on same level from slipping, tripping and stumbling	0.631	0.369
W00 Fall on same level involving ice and snow	0.631	0.369
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.630	0.370
M05-M14 Inflammatory polyarthropathies	0.630	0.370
S01 Open wound of head	0.630	0.370
G70 Myasthenia gravis and other myoneural disorders	0.630	0.370
M47.84 Other spondylosis (Thoracic region)	0.629	0.371
Y04 Assault by bodily force	0.628	0.371
B50-B64 Protozoal diseases	0.628	0.371
H17 Corneal scars and opacities	0.628	0.372
W17 Other fall from one level to another	0.627	0.373
Y41 Other systemic anti-infectives and antiparasitics	0.627	0.373
S62 Fracture at wrist and hand level	0.627	0.373
S42.0 Fracture of clavicle	0.626	0.374
S92.2 Fracture of other tarsal bone(s)	0.626	0.374
D37.0 Lip, oral cavity and pharynx	0.626	0.374
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.626	0.374
H60 Otitis externa	0.625	0.374
C18.8 Overlapping lesion of colon	0.625	0.375
W49 Exposure to other and unspecified inanimate mechanical forces	0.625	0.375
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.624	0.376
S06 Intracranial injury	0.624	0.376
F60.9 Personality disorder, unspecified	0.624	0.376
W87 Exposure to unspecified electric current	0.623	0.377
M47.0 Anterior spinal and vertebral artery compression syndromes	0.623	0.377
Y59 Other and unspecified vaccines and biological substances	0.622	0.378
Y58 Bacterial vaccines	0.622	0.378
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.622	0.378
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.622	0.378
Y53 Agents primarily affecting the gastro-intestinal system	0.622	0.378
Y50 Central nervous system stimulants, not elsewhere classified	0.622	0.378
Y48 Anaesthetics and therapeutic gases	0.622	0.378
Y47 Sedatives, hypnotics and antianxiety drugs	0.622	0.378
H80 Otosclerosis	0.622	0.378
T88.9 Complication of surgical and medical care, unspecified	0.621	0.378
T88.3 Malignant hyperthermia due to anaesthesis	0.621	0.378
T88.2 Shock due to anaesthesia	0.621	0.378
T88.1 Other complications following immunisation, not elsewhere classified	0.621	0.378
T88.0 Infection following immunisation	0.621	0.378
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.621	0.379
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.621	0.379
T25 Burn and corrosion of ankle and foot	0.621	0.379
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.621	0.379
T20 Burn and corrosion of head and neck	0.621	0.379
H74.9 Disorder of middle ear and mastoid, unspecified	0.621	0.379
H81 Disorders of vestibular function	0.621	0.379
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.620	0.380
C21.0 Anus, unspecified	0.620	0.380
L20-L30 Dermatitis and eczema	0.618	0.382
Y60-Y69 Misadventures to patients during surgical and medical care	0.615	0.385
C16.0 Cardia	0.615	0.385
F40.0 Agoraphobia	0.615	0.385
M63 Disorders of muscle in diseases classified elsewhere	0.614	0.386
M61 Calcification and ossification of muscle	0.614	0.386
M60 Myositis	0.614	0.386
Y54.5 Other diuretics	0.613	0.387
G00 Bacterial meningitis, not elsewhere classified	0.612	0.388
M84 Disorders of continuity of bone	0.612	0.388
F45 Somatoform disorders	0.611	0.389
C18.0 Caecum	0.608	0.392
M21 Other acquired deformities of limbs	0.606	0.393
W20 Struck by thrown, projected or falling object	0.606	0.393
T14 Injury of unspecified body region	0.606	0.394
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.606	0.394
S41.7 Multiple open wounds of shoulder and upper arm	0.606	0.394
T18 Foreign body in alimentary tract	0.605	0.395
S43.1 Dislocation of acromioclavicular joint	0.605	0.395
S56 Injury of muscle and tendon at forearm level	0.604	0.396
M86-M90 Other osteopathies	0.604	0.396
G51 Facial nerve disorders	0.604	0.396
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.603	0.397
G54.9 Nerve root and plexus disorder, unspecified	0.603	0.397
G72 Other myopathies	0.603	0.397
H31 Other disorders of choroid	0.602	0.398
G30-G32 Other degenerative diseases of the nervous system	0.602	0.398
G83 Other paralytic syndromes	0.601	0.398
E00-E07 Disorders of thyroid gland	0.601	0.399
H93 Other disorders of ear, not elsewhere classified	0.601	0.399
H72.9 Perforation of tympanic membrane, unspecified	0.601	0.399
B90-B94 Sequelae of infectious and parasitic diseases	0.601	0.399
W13 Fall from, out of or through building or structure	0.600	0.400
G90 Disorders of autonomic nervous system	0.600	0.400
Q63.0 Accessory kidney	0.600	0.400
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.599	0.400
C25 Malignant neoplasm of pancreas	0.599	0.401
F48 Other neurotic disorders	0.599	0.401
F44 Dissociative [conversion] disorders	0.599	0.401
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.599	0.401
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.599	0.401
S69 Other and unspecified injuries of wrist and hand	0.599	0.401
B85-B89 Pediculosis, acariasis and other infestations	0.598	0.402

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations