TreeWAS – Variant ID: rs11627967

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.545	0.455	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.537	0.463	0.000
Chapter XI Diseases of the digestive system	0.536	0.464	0.000
K40-K46 Hernia	0.536	0.464	0.000
K44 Diaphragmatic hernia	0.536	0.464	0.000
Chapter VII Diseases of the eye and adnexa	0.521	0.479	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.518	0.482	0.000
M70-M79 Other soft tissue disorders	0.511	0.489	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.508	0.492	0.000
M75 Shoulder lesions	0.502	0.498	0.000
Chapter XIV Diseases of the genitourinary system	0.499	0.501	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.498	0.502	0.000
Chapter I Certain infectious and parasitic diseases	0.482	0.518	0.000
N30-N39 Other diseases of urinary system	0.481	0.519	0.000
M75.4 Impingement syndrome of shoulder	0.476	0.524	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.475	0.525	0.000
H40-H42 Glaucoma	0.463	0.537	0.000
K21 Gastro-oesophageal reflux disease	0.459	0.541	0.000
Chapter X Diseases of the respiratory system	0.456	0.544	0.000
N35 Urethral stricture	0.447	0.553	0.000
Chapter IX Diseases of the circulatory system	0.446	0.554	0.000
K22 Other diseases of oesophagus	0.444	0.556	0.000
K43 Ventral hernia	0.444	0.556	0.000
N60-N64 Disorders of breast	0.443	0.557	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.441	0.559	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.439	0.561	0.000
K35-K38 Diseases of appendix	0.437	0.563	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.436	0.564	0.000
I30-I52 Other forms of heart disease	0.436	0.564	0.000
H53-H54 Visual disturbances and blindness	0.435	0.565	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.434	0.566	0.000
M45-M49 Spondylopathies	0.433	0.567	0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.432	0.568	0.000
K65-K67 Diseases of peritoneum	0.428	0.572	0.000
B95-B98 Bacterial, viral and other infectious agents	0.428	0.572	0.000
M75.5 Bursitis of shoulder	0.426	0.574	0.000
S60-S69 Injuries to the wrist and hand	0.426	0.574	0.000
M75.1 Rotator cuff syndrome	0.425	0.575	0.000
Chapter VIII Diseases of the ear and mastoid process	0.424	0.576	0.000
N35.9 Urethral stricture, unspecified	0.422	0.578	0.000
H40 Glaucoma	0.422	0.578	0.000
K42 Umbilical hernia	0.420	0.580	0.000
N10-N16 Renal tubulo-interstitial diseases	0.418	0.582	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.412	0.588	0.000
I34 Nonrheumatic mitral valve disorders	0.412	0.588	0.000
N32 Other disorders of bladder	0.410	0.590	0.000
O00-O08 Pregnancy with abortive outcome	0.409	0.590	0.000
H25-H28 Disorders of lens	0.405	0.594	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.405	0.595	0.000
N25-N29 Other disorders of kidney and ureter	0.404	0.596	0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.402	0.598	0.000
O60-O75 Complications of labour and delivery	0.402	0.598	0.000
H30-H36 Disorders of choroid and retina	0.401	0.599	0.000
S70-S79 Injuries to the hip and thigh	0.399	0.601	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.397	0.603	0.000
K22.8 Other specified diseases of oesophagus	0.397	0.603	0.000
I34.0 Mitral (valve) insufficiency	0.396	0.604	0.000
M91-M94 Chondropathies	0.396	0.604	0.000
M65-M68 Disorders of synovium and tendon	0.394	0.606	0.000
M40-M43 Deforming dorsopathies	0.392	0.608	0.000
Chapter XXII Codes for special purposes	0.391	0.609	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.391	0.609	0.000
I47 Paroxysmal tachycardia	0.390	0.610	0.000
J90-J94 Other diseases of pleura	0.387	0.613	0.000
B35-B49 Mycoses	0.387	0.613	0.000
I42 Cardiomyopathy	0.387	0.613	0.000
K37 Unspecified appendicitis	0.386	0.614	0.000
S90-S99 Injuries to the ankle and foot	0.386	0.614	0.000
S40-S49 Injuries to the shoulder and upper arm	0.386	0.614	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.385	0.615	0.000
S00-S09 Injuries to the head	0.385	0.615	0.000
K46 Unspecified abdominal hernia	0.384	0.615	0.000
K45 Other abdominal hernia	0.384	0.615	0.000
K44.1 Diaphragmatic hernia with gangrene	0.384	0.616	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.384	0.616	0.000
S80-S89 Injuries to the knee and lower leg	0.380	0.620	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.380	0.620	0.000
N32.0 Bladder-neck obstruction	0.379	0.621	0.000
A30-A49 Other bacterial diseases	0.379	0.621	0.000
M47 Spondylosis	0.379	0.621	0.000
K41 Femoral hernia	0.378	0.622	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.378	0.622	0.000
M79.8 Other specified soft tissue disorders	0.377	0.623	0.000
Chapter XX External causes of morbidity and mortality	0.376	0.624	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.376	0.624	0.000
H60-H62 Diseases of external ear	0.375	0.625	0.000
Chapter VI Diseases of the nervous system	0.374	0.626	0.000
H55-H59 Other disorders of eye and adnexa	0.374	0.626	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.374	0.626	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.374	0.626	0.000
H10-H13 Disorders of conjunctiva	0.374	0.626	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.374	0.626	0.000
N64 Other disorders of breast	0.373	0.627	0.000
K04 Diseases of pulp and periapical tissues	0.372	0.628	0.000
M80-M85 Disorders of bone density and structure	0.371	0.629	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.371	0.629	0.000
M86-M90 Other osteopathies	0.371	0.629	0.000
M60-M63 Disorders of muscles	0.371	0.629	0.000
M00-M03 Infectious arthropathies	0.371	0.629	0.000
J30-J39 Other diseases of upper respiratory tract	0.371	0.629	0.000
H25 Senile cataract	0.369	0.631	0.000
N99-N99 Other disorders of the genitourinary system	0.368	0.632	0.000
H43-H45 Disorders of vitreous body and globe	0.367	0.633	0.000
M77 Other enthesopathies	0.366	0.634	0.000
M76 Enthesopathies of lower limb, excluding foot	0.366	0.634	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.366	0.634	0.000
M71 Other bursopathies	0.366	0.634	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.366	0.634	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.366	0.634	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.365	0.635	0.000
N30 Cystitis	0.365	0.635	0.000
I44 Atrioventricular and left bundle-branch block	0.365	0.635	0.000
O85-O92 Complications predominantly related to the puerperium	0.364	0.636	0.000
O42 Premature rupture of membranes	0.364	0.636	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.364	0.636	0.000
H53 Visual disturbances	0.363	0.637	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.361	0.639	0.000
M75.8 Other shoulder lesions	0.360	0.640	0.000
M75.9 Shoulder lesion, unspecified	0.360	0.640	0.000
M75.3 Calcific tendinitis of shoulder	0.360	0.640	0.000
M75.2 Bicipital tendinitis	0.360	0.640	0.000
K30 Dyspepsia	0.359	0.641	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.359	0.641	0.000
M75.0 Adhesive capsulitis of shoulder	0.359	0.641	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.358	0.642	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.357	0.643	0.000
T79-T79 Certain early complications of trauma	0.357	0.643	0.000
T66-T78 Other and unspecified effects of external causes	0.357	0.643	0.000
T33-T35 Frostbite	0.357	0.643	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.357	0.643	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.357	0.643	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.357	0.643	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.357	0.643	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.357	0.643	0.000
T00-T07 Injuries involving multiple body regions	0.357	0.643	0.000
S10-S19 Injuries to the neck	0.357	0.643	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.357	0.643	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.357	0.643	0.000
O23 Infections of genito-urinary tract in pregnancy	0.355	0.645	0.000
J09-J18 Influenza and pneumonia	0.354	0.646	0.000
K70-K77 Diseases of liver	0.354	0.646	0.000
J95-J99 Other diseases of the respiratory system	0.353	0.647	0.000
H40.9 Glaucoma, unspecified	0.353	0.647	0.000
K22.4 Dyskinesia of oesophagus	0.352	0.648	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.352	0.648	0.000
N13 Obstructive and reflux uropathy	0.352	0.648	0.000
S50-S59 Injuries to the elbow and forearm	0.351	0.649	0.000
K66 Other disorders of peritoneum	0.351	0.649	0.000
N60 Benign mammary dysplasia	0.351	0.649	0.000
N39 Other disorders of urinary system	0.350	0.650	0.000
S20-S29 Injuries to the thorax	0.349	0.650	0.000
K22.1 Ulcer of oesophagus	0.348	0.652	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.347	0.653	0.000
K50-K52 Noninfective enteritis and colitis	0.347	0.653	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.346	0.654	0.000
B99-B99 Other infectious diseases	0.346	0.654	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.346	0.654	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.346	0.654	0.000
B65-B83 Helminthiases	0.346	0.654	0.000
B50-B64 Protozoal diseases	0.346	0.654	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.346	0.654	0.000
B15-B19 Viral hepatitis	0.346	0.654	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.346	0.654	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.346	0.654	0.000
A80-A89 Viral infections of the central nervous system	0.346	0.654	0.000
A75-A79 Rickettsioses	0.346	0.654	0.000
A70-A74 Other diseases caused by chlamydiae	0.346	0.654	0.000
A65-A69 Other spirochaetal diseases	0.346	0.654	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.346	0.654	0.000
A20-A28 Certain zoonotic bacterial diseases	0.346	0.654	0.000
A15-A19 Tuberculosis	0.346	0.654	0.000
H04 Disorders of lachrymal system	0.345	0.655	0.000
N37 Urethral disorders in diseases classified elsewhere	0.345	0.655	0.000
N36 Other disorders of urethra	0.345	0.655	0.000
N34 Urethritis and urethral syndrome	0.345	0.655	0.000
N33 Bladder disorders in diseases classified elsewhere	0.345	0.655	0.000
M79.7 Fibromyalgia	0.344	0.656	0.000
J60-J70 Lung diseases due to external agents	0.344	0.656	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.344	0.656	0.000
H33 Retinal detachments and breaks	0.343	0.657	0.000
I47.1 Supraventricular tachycardia	0.343	0.657	0.000
K12 Stomatitis and related lesions	0.342	0.658	0.000
N61 Inflammatory disorders of breast	0.342	0.658	0.000
N00-N08 Glomerular diseases	0.342	0.658	0.000
K22.9 Disease of oesophagus, unspecified	0.342	0.658	0.000
N32.3 Diverticulum of bladder	0.341	0.659	0.000
O20 Haemorrhage in early pregnancy	0.341	0.659	0.000
K28 Gastrojejunal ulcer	0.341	0.659	0.000
K27 Peptic ulcer, site unspecified	0.341	0.659	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.341	0.659	0.000
L20-L30 Dermatitis and eczema	0.340	0.660	0.000
M47.9 Spondylosis, unspecified	0.340	0.660	0.000
K14 Diseases of tongue	0.338	0.662	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.338	0.662	0.000
I42.0 Dilated cardiomyopathy	0.337	0.663	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.337	0.663	0.000
N10 Acute tubulo-interstitial nephritis	0.337	0.663	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.336	0.664	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.336	0.664	0.000
I05-I09 Chronic rheumatic heart diseases	0.336	0.664	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.336	0.664	0.000
M72 Fibroblastic disorders	0.336	0.664	0.000
K02 Dental caries	0.335	0.665	0.000
H40.0 Glaucoma suspect	0.333	0.667	0.000
H40.2 Primary angle-closure glaucoma	0.333	0.667	0.000
H42 Glaucoma in diseases classified elsewhere	0.332	0.668	0.000
S62 Fracture at wrist and hand level	0.332	0.668	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.332	0.668	0.000
H40.1 Primary open-angle glaucoma	0.332	0.668	0.000
J92 Pleural plaque	0.331	0.669	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.331	0.669	0.000
K04.5 Chronic apical periodontitis	0.331	0.669	0.000
K40 Inguinal hernia	0.330	0.669	0.001
H54 Blindness and low vision	0.330	0.669	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.330	0.670	0.000
H61 Other disorders of external ear	0.329	0.670	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.329	0.671	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.327	0.673	0.000
I49 Other cardiac arrhythmias	0.327	0.673	0.000
S72 Fracture of femur	0.327	0.673	0.000
S64 Injury of nerves at wrist and hand level	0.326	0.673	0.000
L50-L54 Urticaria and erythema	0.326	0.674	0.000
I60-I69 Cerebrovascular diseases	0.326	0.674	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.325	0.674	0.000
O04 Medical abortion	0.325	0.675	0.000
G30-G32 Other degenerative diseases of the nervous system	0.325	0.675	0.000
M79.0 Rheumatism, unspecified	0.324	0.676	0.000
N63 Unspecified lump in breast	0.324	0.676	0.000
O80-O84 Delivery	0.324	0.676	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.324	0.676	0.000
M45 Ankylosing spondylitis	0.324	0.676	0.000
L40-L45 Papulosquamous disorders	0.323	0.677	0.000
L03 Cellulitis	0.322	0.678	0.000
B25-B34 Other viral diseases	0.321	0.679	0.000
N35.8 Other urethral stricture	0.320	0.679	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.320	0.679	0.000
N35.0 Posttraumatic urethral stricture	0.320	0.679	0.000
I00-I02 Acute rheumatic fever	0.320	0.680	0.000
B37 Candidiasis	0.319	0.681	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.319	0.681	0.000
K22.5 Diverticulum of oesophagus, acquired	0.318	0.681	0.000
K22.3 Perforation of oesophagus	0.318	0.681	0.000
K22.0 Achalasia of cardia	0.318	0.681	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.318	0.682	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.318	0.682	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.318	0.682	0.000
K43.4 Parastomal hernia with gangrene	0.318	0.682	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.318	0.682	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.318	0.682	0.000
K43.1 Ventral hernia with gangrene	0.318	0.682	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.318	0.682	0.000
N62 Hypertrophy of breast	0.318	0.682	0.000
J00-J06 Acute upper respiratory infections	0.317	0.682	0.000
K05 Gingivitis and periodontal diseases	0.317	0.683	0.000
K22.7 Barrett's oesophagus	0.317	0.683	0.000
K26 Duodenal ulcer	0.317	0.683	0.000
M79.9 Soft tissue disorder, unspecified	0.316	0.684	0.000
M79.5 Residual foreign body in soft tissue	0.316	0.684	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.316	0.684	0.000
M79.3 Panniculitis, unspecified	0.316	0.684	0.000
M79.2 Neuralgia and neuritis, unspecified	0.316	0.684	0.000
M79.1 Myalgia	0.316	0.684	0.000
O29 Complications of anaesthesia during pregnancy	0.315	0.685	0.000
O28 Abnormal findings on antenatal screening of mother	0.315	0.685	0.000
O24 Diabetes mellitus in pregnancy	0.315	0.685	0.000
O22 Venous complications in pregnancy	0.315	0.685	0.000
O21 Excessive vomiting in pregnancy	0.315	0.685	0.000
O25 Malnutrition in pregnancy	0.315	0.685	0.000
J35 Chronic diseases of tonsils and adenoids	0.315	0.685	0.000
S40 Superficial injury of shoulder and upper arm	0.314	0.686	0.000
K38 Other diseases of appendix	0.313	0.687	0.000
K36 Other appendicitis	0.313	0.687	0.000
O42.9 Premature rupture of membranes, unspecified	0.313	0.687	0.000
K11 Diseases of salivary glands	0.313	0.687	0.000
K10 Other diseases of jaws	0.313	0.687	0.000
K09 Cysts of oral region, not elsewhere classified	0.313	0.687	0.000
K07 Dentofacial anomalies [including malocclusion]	0.313	0.687	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.313	0.687	0.000
K03 Other diseases of hard tissues of teeth	0.313	0.687	0.000
K00 Disorders of tooth development and eruption	0.313	0.687	0.000
I47.2 Ventricular tachycardia	0.313	0.687	0.000
I52 Other heart disorders in diseases classified elsewhere	0.312	0.687	0.000
I48 Atrial fibrillation and flutter	0.312	0.687	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.312	0.687	0.000
I41 Myocarditis in diseases classified elsewhere	0.312	0.687	0.000
I40 Acute myocarditis	0.312	0.687	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.312	0.687	0.000
I37 Pulmonary valve disorders	0.312	0.687	0.000
I36 Nonrheumatic tricuspid valve disorders	0.312	0.687	0.000
I33 Acute and subacute endocarditis	0.312	0.687	0.000
I32 Pericarditis in diseases classified elsewhere	0.312	0.687	0.000
I30 Acute pericarditis	0.312	0.687	0.000
I38 Endocarditis, valve unspecified	0.312	0.687	0.000
O03 Spontaneous abortion	0.312	0.688	0.000
H33.3 Retinal breaks without detachment	0.312	0.688	0.000
L10-L14 Bullous disorders	0.311	0.688	0.000
H25.9 Senile cataract, unspecified	0.311	0.689	0.000
M49 Spondylopathies in diseases classified elsewhere	0.311	0.689	0.000
M46 Other inflammatory spondylopathies	0.311	0.689	0.000
I42.9 Cardiomyopathy, unspecified	0.311	0.689	0.000
I44.1 Atrioventricular block, second degree	0.310	0.690	0.000
N20-N23 Urolithiasis	0.310	0.690	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.309	0.690	0.000
N64.5 Other signs and symptoms in breast	0.309	0.691	0.000
M94 Other disorders of cartilage	0.308	0.691	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.307	0.693	0.000
K65 Peritonitis	0.307	0.693	0.000
M50-M54 Other dorsopathies	0.307	0.693	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.307	0.693	0.000
M79.6 Pain in limb	0.307	0.693	0.000
G90-G99 Other disorders of the nervous system	0.307	0.693	0.000
M65 Synovitis and tenosynovitis	0.306	0.694	0.000
S91 Open wound of ankle and foot	0.306	0.694	0.000
S69 Other and unspecified injuries of wrist and hand	0.305	0.694	0.000
S68 Traumatic amputation of wrist and hand	0.305	0.694	0.000
S67 Crushing injury of wrist and hand	0.305	0.694	0.000
S65 Injury of blood vessels at wrist and hand level	0.305	0.694	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.305	0.694	0.000
S60 Superficial injury of wrist and hand	0.305	0.694	0.000
I71 Aortic aneurysm and dissection	0.305	0.695	0.000
H25.8 Other senile cataract	0.304	0.696	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.303	0.697	0.000
H40.8 Other glaucoma	0.303	0.697	0.000
H40.6 Glaucoma secondary to drugs	0.303	0.697	0.000
H40.5 Glaucoma secondary to other eye disorders	0.303	0.697	0.000
H40.4 Glaucoma secondary to eye inflammation	0.303	0.697	0.000
H40.3 Glaucoma secondary to eye trauma	0.303	0.697	0.000
I45 Other conduction disorders	0.303	0.697	0.000
N40-N51 Diseases of male genital organs	0.302	0.698	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.302	0.698	0.000
K42.1 Umbilical hernia with gangrene	0.301	0.699	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.301	0.699	0.000
A00-A09 Intestinal infectious diseases	0.300	0.700	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.300	0.700	0.000
N15 Other renal tubulo-interstitial diseases	0.300	0.700	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.300	0.700	0.000
N11 Chronic tubulo-interstitial nephritis	0.300	0.700	0.000
O63 Long labour	0.300	0.700	0.000
H53.4 Visual field defects	0.299	0.701	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.299	0.701	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.298	0.702	0.000
H36 Retinal disorders in diseases classified elsewhere	0.298	0.702	0.000
E20-E35 Disorders of other endocrine glands	0.298	0.702	0.000
H25.0 Senile incipient cataract	0.298	0.702	0.000
I46 Cardiac arrest	0.297	0.702	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.297	0.702	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.297	0.703	0.000
K22.2 Oesophageal obstruction	0.297	0.703	0.000
H61.0 Perichondritis of external ear	0.297	0.703	0.000
J93 Pneumothorax	0.297	0.703	0.000
A49 Bacterial infection of unspecified site	0.296	0.704	0.000
S82 Fracture of lower leg, including ankle	0.296	0.704	0.000
K66.0 Peritoneal adhesions	0.296	0.704	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.295	0.704	0.000
O45 Premature separation of placenta [abruptio placentae]	0.295	0.704	0.000
O44 Placenta praevia	0.295	0.704	0.000
O43 Placental disorders	0.295	0.704	0.000
O41 Other disorders of amniotic fluid and membranes	0.295	0.704	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.295	0.704	0.000
O33 Maternal care for known or suspected disproportion	0.295	0.704	0.000
O31 Complications specific to multiple gestation	0.295	0.704	0.000
O30 Multiple gestation	0.295	0.704	0.000
O40 Polyhydramnios	0.295	0.704	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.295	0.705	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.295	0.705	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.295	0.705	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.295	0.705	0.000
O02 Other abnormal products of conception	0.295	0.705	0.000
L03.1 Cellulitis of other parts of limb	0.295	0.705	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.295	0.705	0.000
N32.4 Rupture of bladder, nontraumatic	0.294	0.706	0.000
N32.2 Vesical fistula, not elsewhere classified	0.294	0.706	0.000
N32.1 Vesicointestinal fistula	0.294	0.706	0.000
M05-M14 Inflammatory polyarthropathies	0.294	0.706	0.000
H60 Otitis externa	0.294	0.706	0.000
M41 Scoliosis	0.294	0.706	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.294	0.706	0.000
O07 Failed attempted abortion	0.294	0.706	0.000
O06 Unspecified abortion	0.294	0.706	0.000
O05 Other abortion	0.294	0.706	0.000
O01 Hydatidiform mole	0.294	0.706	0.000
O00 Ectopic pregnancy	0.294	0.706	0.000
I95 Hypotension	0.293	0.707	0.000
S09 Other and unspecified injuries of head	0.293	0.707	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.292	0.708	0.000
H80-H83 Diseases of inner ear	0.292	0.708	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.291	0.709	0.000
H27 Other disorders of lens	0.291	0.709	0.000
N28.1 Cyst of kidney, acquired	0.291	0.709	0.000
N64.8 Other specified disorders of breast	0.291	0.709	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.291	0.709	0.000
H05 Disorders of orbit	0.291	0.709	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.291	0.709	0.000
H01 Other inflammation of eyelid	0.291	0.709	0.000
M84 Disorders of continuity of bone	0.290	0.709	0.000
S02 Fracture of skull and facial bones	0.290	0.709	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.290	0.709	0.000
S00 Superficial injury of head	0.290	0.710	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.290	0.710	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.290	0.710	0.000
M43 Other deforming dorsopathies	0.290	0.710	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.290	0.710	0.000
N27 Small kidney of unknown cause	0.290	0.710	0.000
N25 Disorders resulting from impaired renal tubular function	0.290	0.710	0.000
N26 Unspecified contracted kidney	0.290	0.710	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.289	0.711	0.000
H04.2 Epiphora	0.288	0.712	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.288	0.712	0.000
O74 Complications of anaesthesia during labour and delivery	0.288	0.712	0.000
O73 Retained placenta and membranes, without haemorrhage	0.288	0.712	0.000
O71 Other obstetric trauma	0.288	0.712	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.288	0.712	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.288	0.712	0.000
O66 Other obstructed labour	0.288	0.712	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.288	0.712	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.288	0.712	0.000
O62 Abnormalities of forces of labour	0.288	0.712	0.000
O61 Failed induction of labour	0.288	0.712	0.000
O60 Preterm delivery	0.288	0.712	0.000
K01 Embedded and impacted teeth	0.288	0.712	0.000
O72 Postpartum haemorrhage	0.287	0.712	0.000
H34 Retinal vascular occlusions	0.287	0.713	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.287	0.713	0.000
H31 Other disorders of choroid	0.287	0.713	0.000
H30 Chorioretinal inflammation	0.287	0.713	0.000
J92.9 Pleural plaque without asbestos	0.287	0.713	0.000
V20-V29 Motorcycle rider injured in transport accident	0.287	0.713	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.287	0.713	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.287	0.713	0.000
S79 Other and unspecified injuries of hip and thigh	0.286	0.714	0.000
S78 Traumatic amputation of hip and thigh	0.286	0.714	0.000
S77 Crushing injury of hip and thigh	0.286	0.714	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.286	0.714	0.000
S75 Injury of blood vessels at hip and thigh level	0.286	0.714	0.000
S74 Injury of nerves at hip and thigh level	0.286	0.714	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.286	0.714	0.000
S71 Open wound of hip and thigh	0.286	0.714	0.000
S70 Superficial injury of hip and thigh	0.286	0.714	0.000
I34.1 Mitral (valve) prolapse	0.286	0.714	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.285	0.714	0.000
N30.1 Interstitial cystitis (chronic)	0.285	0.715	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.285	0.715	0.000
Q80-Q89 Other congenital malformations	0.285	0.715	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.285	0.715	0.000
Q60-Q64 Congenital malformations of the urinary system	0.285	0.715	0.000
Q50-Q56 Congenital malformations of genital organs	0.285	0.715	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.285	0.715	0.000
Q35-Q37 Cleft lip and cleft palate	0.285	0.715	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.285	0.715	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.285	0.715	0.000
Q00-Q07 Congenital malformations of the nervous system	0.285	0.715	0.000
K31 Other diseases of stomach and duodenum	0.284	0.716	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.284	0.716	0.000
L60-L75 Disorders of skin appendages	0.284	0.716	0.000
M93 Other osteochondropathies	0.284	0.716	0.000
M92 Other juvenile osteochondrosis	0.284	0.716	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.284	0.716	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.284	0.716	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.283	0.717	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.283	0.717	0.000
M66 Spontaneous rupture of synovium and tendon	0.283	0.717	0.000
H50 Other strabismus	0.283	0.717	0.000
N60.0 Solitary cyst of breast	0.283	0.717	0.000
A41 Other septicaemia	0.283	0.717	0.000
I31 Other diseases of pericardium	0.282	0.717	0.000
H90-H95 Other disorders of ear	0.282	0.717	0.000
M67 Other disorders of synovium and tendon	0.282	0.717	0.000
Chapter V Mental and behavioural disorders	0.282	0.718	0.000
I51 Complications and ill-defined descriptions of heart disease	0.282	0.718	0.000
S61 Open wound of wrist and hand	0.282	0.718	0.000
M42 Spinal osteochondrosis	0.281	0.719	0.000
M40 Kyphosis and lordosis	0.281	0.719	0.000
M48 Other spondylopathies	0.281	0.719	0.000
P90-P96 Other disorders originating in the perinatal period	0.280	0.719	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.280	0.719	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.280	0.719	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.280	0.719	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.280	0.719	0.000
P35-P39 Infections specific to the perinatal period	0.280	0.719	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.280	0.719	0.000
P10-P15 Birth trauma	0.280	0.719	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.280	0.719	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.280	0.719	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.280	0.719	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.280	0.719	0.000
J18 Pneumonia, organism unspecified	0.280	0.720	0.000
O47 False labour	0.280	0.720	0.000
N17-N19 Renal failure	0.280	0.720	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.280	0.720	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.280	0.720	0.000
I47.0 Reentry ventricular arrhythmia	0.280	0.720	0.000
J98 Other respiratory disorders	0.279	0.721	0.000
W00-W19 Falls	0.279	0.721	0.000
O26.8 Other specified pregnancy-related conditions	0.278	0.722	0.000
B48 Other mycoses, not elsewhere classified	0.278	0.722	0.000
B47 Mycetoma	0.278	0.722	0.000
B46 Zygomycosis	0.278	0.722	0.000
B45 Cryptococcosis	0.278	0.722	0.000
B44 Aspergillosis	0.278	0.722	0.000
B43 Chromomycosis and phaeomycotic abscess	0.278	0.722	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations