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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116367285
log Bayes Factor = 12.3707
Chromosome 3   position 65,094,139  (GRCh37) Explore rs116367285 on Ensembl!
Variant rs116367285 is part of Cluster X0164

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.995 0.005 0.000
Z87 Personal history of other diseases and conditions
0.994 0.006 0.000
Z87.1 Personal history of diseases of the digestive system
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.982 0.018 0.000
J30-J39 Other diseases of upper respiratory tract
0.976 0.024 0.000
Chapter II Neoplasms
0.974 0.026 0.000
M20-M25 Other joint disorders
0.965 0.035 0.000
C15-C26 Malignant neoplasms of digestive organs
0.963 0.037 0.000
K35-K38 Diseases of appendix
0.962 0.038 0.000
K55-K64 Other diseases of intestines
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
M80-M85 Disorders of bone density and structure
0.950 0.050 0.000
A00-A09 Intestinal infectious diseases
0.949 0.051 0.000
J32 Chronic sinusitis
0.948 0.052 0.000
M70-M79 Other soft tissue disorders
0.943 0.057 0.000
K35 Acute appendicitis
0.942 0.058 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.941 0.059 0.000
C18 Malignant neoplasm of colon
0.941 0.059 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.939 0.061 0.000
J32.9 Chronic sinusitis, unspecified
0.937 0.063 0.000
K65-K67 Diseases of peritoneum
0.937 0.063 0.000
K50-K52 Noninfective enteritis and colitis
0.936 0.064 0.000
K60 Fissure and fistula of anal and rectal regions
0.932 0.068 0.000
K70-K77 Diseases of liver
0.931 0.069 0.000
M15-M19 Arthrosis
0.931 0.069 0.000
Z93 Artificial opening status
0.929 0.071 0.000
Z96 Presence of other functional implants
0.928 0.072 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.928 0.072 0.000
K35.9 Acute appendicitis, unspecified
0.924 0.076 0.000
H90-H95 Other disorders of ear
0.924 0.076 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.915 0.085 0.000
K50 Crohn's disease [regional enteritis]
0.914 0.086 0.000
A30-A49 Other bacterial diseases
0.908 0.092 0.000
M81 Osteoporosis without pathological fracture
0.905 0.095 0.000
M16 Coxarthrosis [arthrosis of hip]
0.902 0.098 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.901 0.099 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.901 0.099 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.900 0.100 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.899 0.101 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.898 0.102 0.000
H80-H83 Diseases of inner ear
0.894 0.106 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.892 0.108 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.891 0.109 0.000
M22 Disorders of patella
0.889 0.111 0.000
J09-J18 Influenza and pneumonia
0.887 0.113 0.000
K66 Other disorders of peritoneum
0.886 0.114 0.000
Z96.0 Presence of urogenital implants
0.885 0.115 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.882 0.118 0.000
Z87.8 Personal history of other specified conditions
0.882 0.118 0.000
C18.7 Sigmoid colon
0.882 0.118 0.000
K50.9 Crohn's disease, unspecified
0.882 0.118 0.000
K60.2 Anal fissure, unspecified
0.880 0.120 0.000
K61 Abscess of anal and rectal regions
0.880 0.120 0.000
M79.8 Other specified soft tissue disorders
0.879 0.121 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.877 0.123 0.000
M81.9 Osteoporosis, unspecified
0.874 0.126 0.000
S60-S69 Injuries to the wrist and hand
0.873 0.127 0.000
M23 Internal derangement of knee
0.870 0.130 0.000
Z88.6 Personal history of allergy to analgesic agent
0.870 0.130 0.000
C18.9 Colon, unspecified
0.869 0.131 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.867 0.133 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.865 0.135 0.000
H65-H75 Diseases of middle ear and mastoid
0.863 0.137 0.000
C20 Malignant neoplasm of rectum
0.863 0.137 0.000
K60.3 Anal fistula
0.854 0.146 0.000
M86-M90 Other osteopathies
0.851 0.149 0.000
Z04 Examination and observation for other reasons
0.848 0.152 0.000
J31.0 Chronic rhinitis
0.848 0.152 0.000
M24 Other specific joint derangements
0.844 0.156 0.000
Chapter XXII Codes for special purposes
0.843 0.157 0.000
H90 Conductive and sensorineural hearing loss
0.838 0.162 0.000
Z80 Family history of malignant neoplasm
0.838 0.162 0.000
K74 Fibrosis and cirrhosis of liver
0.836 0.164 0.000
H81 Disorders of vestibular function
0.836 0.164 0.000
M16.9 Coxarthrosis, unspecified
0.835 0.165 0.000
K66.0 Peritoneal adhesions
0.834 0.166 0.000
B25-B34 Other viral diseases
0.832 0.168 0.000
Z93.2 Ileostomy status
0.831 0.169 0.000
B15-B19 Viral hepatitis
0.831 0.169 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.828 0.172 0.000
J40-J47 Chronic lower respiratory diseases
0.828 0.172 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.828 0.172 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.827 0.173 0.000
Chapter VII Diseases of the eye and adnexa
0.826 0.174 0.000
K61.0 Anal abscess
0.823 0.177 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.821 0.179 0.000
M22.4 Chondromalacia patellae
0.818 0.182 0.000
Z96.6 Presence of orthopaedic joint implants
0.817 0.183 0.000
Z99.3 Dependence on wheelchair
0.816 0.184 0.000
J36 Peritonsillar abscess
0.815 0.185 0.000
M07 Psoriatic and enteropathic arthropathies
0.814 0.186 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.813 0.187 0.000
K58 Irritable bowel syndrome
0.813 0.187 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.810 0.190 0.000
C51-C58 Malignant neoplasms of female genital organs
0.808 0.192 0.000
B35-B49 Mycoses
0.807 0.193 0.000
J45 Asthma
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.807 0.193 0.000
S50-S59 Injuries to the elbow and forearm
0.805 0.195 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.804 0.196 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
K35.8 Acute appendicitis, other and unspecified
0.802 0.198 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.801 0.199 0.000
C78.0 Secondary malignant neoplasm of lung
0.799 0.201 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.798 0.202 0.000
A08 Viral and other specified intestinal infections
0.797 0.203 0.000
A41 Other septicaemia
0.797 0.203 0.000
M21 Other acquired deformities of limbs
0.797 0.203 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.796 0.204 0.000
M16.1 Other primary coxarthrosis
0.796 0.204 0.000
J45.9 Asthma, unspecified
0.794 0.206 0.000
L40-L45 Papulosquamous disorders
0.792 0.208 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.792 0.208 0.000
Z87.0 Personal history of diseases of the respiratory system
0.791 0.209 0.000
M31 Other necrotising vasculopathies
0.789 0.210 0.000
M60-M63 Disorders of muscles
0.789 0.211 0.000
K72 Hepatic failure, not elsewhere classified
0.785 0.215 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.784 0.216 0.000
K75 Other inflammatory liver diseases
0.783 0.217 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.779 0.221 0.000
E10-E14 Diabetes mellitus
0.777 0.223 0.000
J33 Nasal polyp
0.776 0.224 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.774 0.226 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.773 0.227 0.000
K50.0 Crohn's disease of small intestine
0.771 0.229 0.000
A49 Bacterial infection of unspecified site
0.771 0.229 0.000
H71 Cholesteatoma of middle ear
0.770 0.230 0.000
E11 Non-insulin-dependent diabetes mellitus
0.770 0.230 0.000
C77.0 Lymph nodes of head, face and neck
0.768 0.232 0.000
E11.9 Without complications
0.767 0.233 0.000
M13 Other arthritis
0.767 0.233 0.000
Z45 Adjustment and management of implanted device
0.765 0.235 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.765 0.235 0.000
M05 Seropositive rheumatoid arthritis
0.764 0.236 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.763 0.237 0.000
V20-V29 Motorcycle rider injured in transport accident
0.760 0.240 0.000
Z93.3 Colostomy status
0.760 0.240 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.759 0.241 0.000
H60-H62 Diseases of external ear
0.758 0.242 0.000
Z04.1 Examination and observation following transport accident
0.757 0.243 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.756 0.244 0.000
M84 Disorders of continuity of bone
0.755 0.244 0.000
Y00-Y09 Assault
0.755 0.245 0.000
C25 Malignant neoplasm of pancreas
0.753 0.247 0.000
M79.6 Pain in limb
0.752 0.248 0.000
Z04.3 Examination and observation following other accident
0.750 0.250 0.000
V40-V49 Car occupant injured in transport accident
0.749 0.251 0.000
H92 Otalgia and effusion of ear
0.746 0.254 0.000
H81.0 Meniere's disease
0.746 0.254 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.742 0.258 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.741 0.259 0.000
Z93.5 Cystostomy status
0.740 0.260 0.000
Z88.2 Personal history of allergy to sulphonamides
0.739 0.261 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.738 0.262 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.737 0.262 0.000
K63 Other diseases of intestine
0.737 0.263 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.736 0.264 0.000
S64 Injury of nerves at wrist and hand level
0.735 0.265 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.735 0.265 0.000
H93 Other disorders of ear, not elsewhere classified
0.735 0.265 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.734 0.266 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.734 0.266 0.000
C77.3 Axillary and upper limb lymph nodes
0.734 0.266 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.733 0.266 0.000
H90.2 Conductive hearing loss, unspecified
0.733 0.267 0.000
M77 Other enthesopathies
0.732 0.267 0.000
M79.7 Fibromyalgia
0.730 0.270 0.000
Z97 Presence of other devices
0.729 0.270 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.729 0.270 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.729 0.271 0.000
C77.9 Lymph node, unspecified
0.728 0.272 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.727 0.272 0.000
M23.8 Other internal derangements of knee
0.727 0.273 0.000
L40 Psoriasis
0.726 0.274 0.000
M24.1 Other articular cartilage disorders
0.726 0.274 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.726 0.274 0.000
Z45.2 Adjustment and management of vascular access device
0.723 0.277 0.000
W50-W64 Exposure to animate mechanical forces
0.723 0.277 0.000
Z48 Other surgical follow-up care
0.722 0.278 0.000
L20-L30 Dermatitis and eczema
0.721 0.279 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.720 0.280 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.720 0.280 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.720 0.280 0.000
C78.7 Secondary malignant neoplasm of liver
0.719 0.281 0.000
Z01.6 Radiological examination, not elsewhere classified
0.719 0.281 0.000
M19 Other arthrosis
0.718 0.282 0.000
S20-S29 Injuries to the thorax
0.718 0.282 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C77.8 Lymph nodes of multiple regions
0.717 0.283 0.000
D00-D09 In situ neoplasms
0.717 0.283 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.717 0.283 0.000
C56 Malignant neoplasm of ovary
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
B18 Chronic viral hepatitis
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.285 0.000
M06.4 Inflammatory polyarthropathy
0.715 0.285 0.000
M06.3 Rheumatoid nodule
0.715 0.285 0.000
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
M06.1 Adult-onset Still's disease
0.715 0.285 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.715 0.285 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.715 0.285 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.715 0.285 0.000
S60 Superficial injury of wrist and hand
0.714 0.285 0.000
J14 Pneumonia due to Haemophilus influenzae
0.714 0.286 0.000
C18.2 Ascending colon
0.714 0.286 0.000
Y40 Systemic antibiotics
0.713 0.287 0.000
Z89 Acquired absence of limb
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
C18.0 Caecum
0.712 0.287 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.712 0.288 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.712 0.288 0.000
H52 Disorders of refraction and accommodation
0.712 0.288 0.000
M23.3 Other meniscus derangements
0.712 0.288 0.000
A41.8 Other specified septicaemia
0.712 0.288 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.711 0.289 0.000
K90-K93 Other diseases of the digestive system
0.711 0.289 0.000
K55 Vascular disorders of intestine
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.710 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.289 0.000
B65-B83 Helminthiases
0.710 0.289 0.000
B50-B64 Protozoal diseases
0.710 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.289 0.000
A80-A89 Viral infections of the central nervous system
0.710 0.289 0.000
A75-A79 Rickettsioses
0.710 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.289 0.000
A65-A69 Other spirochaetal diseases
0.710 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.289 0.000
A15-A19 Tuberculosis
0.710 0.289 0.000
J32.8 Other chronic sinusitis
0.710 0.290 0.000
X60-X84 Intentional self-harm
0.710 0.290 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.709 0.290 0.000
M87 Osteonecrosis
0.709 0.291 0.000
K66.8 Other specified disorders of peritoneum
0.709 0.291 0.000
K65 Peritonitis
0.706 0.294 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.705 0.295 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
C77.1 Intrathoracic lymph nodes
0.703 0.297 0.000
Z99.8 Dependence on other enabling machines and devices
0.703 0.297 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.703 0.297 0.000
J40 Bronchitis, not specified as acute or chronic
0.702 0.298 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.702 0.298 0.000
M06.0 Seronegative rheumatoid arthritis
0.701 0.299 0.000
M71 Other bursopathies
0.701 0.299 0.000
J34 Other disorders of nose and nasal sinuses
0.701 0.299 0.000
S52 Fracture of forearm
0.701 0.299 0.000
M22.3 Other derangements of patella
0.700 0.300 0.000
J37 Chronic laryngitis and laryngotracheitis
0.700 0.300 0.000
Z93.1 Gastrostomy status
0.700 0.300 0.000
Chapter V Mental and behavioural disorders
0.700 0.300 0.000
M85 Other disorders of bone density and structure
0.699 0.301 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.699 0.301 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.699 0.301 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.699 0.301 0.000
Z88.0 Personal history of allergy to penicillin
0.698 0.302 0.000
K74.6 Other and unspecified cirrhosis of liver
0.698 0.302 0.000
M16.0 Primary coxarthrosis, bilateral
0.698 0.302 0.000
M79.1 Myalgia
0.697 0.303 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.696 0.304 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.696 0.304 0.000
Z13 Special screening examination for other diseases and disorders
0.695 0.305 0.000
M11 Other crystal arthropathies
0.694 0.306 0.000
M22.2 Patellofemoral disorders
0.693 0.307 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.692 0.308 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.692 0.308 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M34 Systemic sclerosis
0.692 0.308 0.000
M33 Dermatopolymyositis
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M30 Polyarteritis nodosa and related conditions
0.692 0.308 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.692 0.308 0.000
J18 Pneumonia, organism unspecified
0.692 0.308 0.000
Z73 Problems related to life-management difficulty
0.691 0.309 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.690 0.310 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.690 0.310 0.000
C21 Malignant neoplasm of anus and anal canal
0.690 0.310 0.000
C17 Malignant neoplasm of small intestine
0.690 0.310 0.000
C23 Malignant neoplasm of gallbladder
0.690 0.310 0.000
K36 Other appendicitis
0.689 0.310 0.000
Z80.6 Family history of leukaemia
0.689 0.311 0.000
A08.4 Viral intestinal infection, unspecified
0.689 0.311 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.688 0.312 0.000
S70-S79 Injuries to the hip and thigh
0.688 0.312 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V80-V89 Other land transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
Z43 Attention to artificial openings
0.686 0.314 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.685 0.315 0.000
Y52 Agents primarily affecting the cardiovascular system
0.685 0.315 0.000
K74.0 Hepatic fibrosis
0.683 0.317 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.683 0.317 0.000
H74 Other disorders of middle ear and mastoid
0.682 0.317 0.000
M07.3 Other psoriatic arthropathies
0.682 0.318 0.000
M83 Adult osteomalacia
0.681 0.319 0.000
M82 Osteoporosis in diseases classified elsewhere
0.681 0.319 0.000
Y44 Agents primarily affecting blood constituents
0.681 0.319 0.000
Y45.0 Opioids and related analgesics
0.681 0.319 0.000
A07 Other protozoal intestinal diseases
0.680 0.319 0.000
A06 Amoebiasis
0.680 0.319 0.000
A05 Other bacterial foodborne intoxications
0.680 0.319 0.000
A03 Shigellosis
0.680 0.319 0.000
A02 Other Salmonella infections
0.680 0.319 0.000
A01 Typhoid and paratyphoid fevers
0.680 0.319 0.000
A00 Cholera
0.680 0.319 0.000
H81.2 Vestibular neuronitis
0.680 0.320 0.000
K63.3 Ulcer of intestine
0.680 0.320 0.000
J32.4 Chronic pansinusitis
0.680 0.320 0.000
J32.3 Chronic sphenoidal sinusitis
0.680 0.320 0.000
J32.2 Chronic ethmoidal sinusitis
0.680 0.320 0.000
J32.1 Chronic frontal sinusitis
0.680 0.320 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.680 0.320 0.000
S10-S19 Injuries to the neck
0.679 0.321 0.000
K72.0 Acute and subacute hepatic failure
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.678 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.678 0.322 0.000
M18 Arthrosis of first carpometacarpal joint
0.678 0.322 0.000
K50.8 Other Crohn's disease
0.677 0.322 0.000
C80 Malignant neoplasm without specification of site
0.677 0.323 0.000
K40-K46 Hernia
0.677 0.323 0.000
K38 Other diseases of appendix
0.676 0.324 0.000
M76 Enthesopathies of lower limb, excluding foot
0.676 0.324 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.676 0.324 0.000
H90.3 Sensorineural hearing loss, bilateral
0.676 0.324 0.000
B37 Candidiasis
0.676 0.324 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.676 0.324 0.000
J00-J06 Acute upper respiratory infections
0.675 0.324 0.000
J33.8 Other polyp of sinus
0.675 0.325 0.000
K50.1 Crohn's disease of large intestine
0.675 0.325 0.000
T33-T35 Frostbite
0.675 0.325 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.675 0.325 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.675 0.325 0.000
T00-T07 Injuries involving multiple body regions
0.675 0.325 0.000
C18.8 Overlapping lesion of colon
0.675 0.325 0.000
C18.6 Descending colon
0.675 0.325 0.000
C18.5 Splenic flexure
0.675 0.325 0.000
C18.3 Hepatic flexure
0.675 0.325 0.000
C18.1 Appendix
0.675 0.325 0.000
K51 Ulcerative colitis
0.675 0.325 0.000
T92 Sequelae of injuries of upper limb
0.674 0.326 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.674 0.326 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.674 0.326 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.672 0.328 0.000
K35.3 Acute appendicitis with localized peritonitis
0.671 0.328 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.671 0.329 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.670 0.329 0.000
Z04.5 Examination and observation following other inflicted injury
0.670 0.330 0.000
M72 Fibroblastic disorders
0.670 0.330 0.000
H81.1 Benign paroxysmal vertigo
0.669 0.331 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.669 0.331 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.669 0.331 0.000
L40.5 Arthropathic psoriasis
0.668 0.332 0.000
B34 Viral infection of unspecified site
0.668 0.332 0.000
K60.5 Anorectal fistula
0.668 0.332 0.000
K60.4 Rectal fistula
0.668 0.332 0.000
K60.0 Acute anal fissure
0.668 0.332 0.000
K77 Liver disorders in diseases classified elsewhere
0.668 0.332 0.000
K73 Chronic hepatitis, not elsewhere classified
0.668 0.332 0.000
K71 Toxic liver disease
0.668 0.332 0.000
L50-L54 Urticaria and erythema
0.668 0.332 0.000
M15 Polyarthrosis
0.668 0.332 0.000
B25 Cytomegaloviral disease
0.667 0.333 0.000
J60-J70 Lung diseases due to external agents
0.666 0.334 0.000
S90-S99 Injuries to the ankle and foot
0.666 0.334 0.000
Z93.9 Artificial opening status, unspecified
0.666 0.334 0.000
Z93.8 Other artificial opening status
0.666 0.334 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.666 0.334 0.000
Z96.9 Presence of functional implant, unspecified
0.665 0.335 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.665 0.335 0.000
Z96.4 Presence of endocrine implants
0.665 0.335 0.000
Z96.3 Presence of artificial larynx
0.665 0.335 0.000
Z96.2 Presence of otological and audiological implants
0.665 0.335 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.665 0.335 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.665 0.335 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.665 0.335 0.000
H50 Other strabismus
0.664 0.335 0.000
H53-H54 Visual disturbances and blindness
0.664 0.336 0.000
M31.6 Other giant cell arteritis
0.664 0.336 0.000
C77.4 Inguinal and lower limb lymph nodes
0.663 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
J20-J22 Other acute lower respiratory infections
0.662 0.337 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.662 0.337 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.662 0.337 0.000
W00-W19 Falls
0.661 0.339 0.000
S61 Open wound of wrist and hand
0.661 0.339 0.000
Z98 Other postsurgical states
0.661 0.339 0.000
K59 Other functional intestinal disorders
0.660 0.340 0.000
A04 Other bacterial intestinal infections
0.660 0.340 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.659 0.341 0.000
J35 Chronic diseases of tonsils and adenoids
0.657 0.343 0.000
M16.7 Other secondary coxarthrosis
0.656 0.343 0.000
M79.9 Soft tissue disorder, unspecified
0.656 0.344 0.000
M79.5 Residual foreign body in soft tissue
0.656 0.344 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.656 0.344 0.000
M79.3 Panniculitis, unspecified
0.656 0.344 0.000
M79.2 Neuralgia and neuritis, unspecified
0.656 0.344 0.000
S69 Other and unspecified injuries of wrist and hand
0.656 0.344 0.000
K74.3 Primary biliary cirrhosis
0.656 0.344 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.655 0.345 0.000
Z88.5 Personal history of allergy to narcotic agent
0.654 0.346 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.654 0.346 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.654 0.346 0.000
Z93.0 Tracheostomy status
0.653 0.347 0.000
M24.5 Contracture of joint
0.653 0.347 0.000
Z42 Follow-up care involving plastic surgery
0.652 0.348 0.000
A48 Other bacterial diseases, not elsewhere classified
0.651 0.349 0.000
A44 Bartonellosis
0.651 0.349 0.000
A43 Nocardiosis
0.651 0.349 0.000
A42 Actinomycosis
0.651 0.349 0.000
A40 Streptococcal septicaemia
0.651 0.349 0.000
A39 Meningococcal infection
0.651 0.349 0.000
A37 Whooping cough
0.651 0.349 0.000
A36 Diphtheria
0.651 0.349 0.000
A32 Listeriosis
0.651 0.349 0.000
A31 Infection due to other mycobacteria
0.651 0.349 0.000
A30 Leprosy [Hansen's disease]
0.651 0.349 0.000
A46 Erysipelas
0.651 0.349 0.000
A38 Scarlet fever
0.651 0.349 0.000
A35 Other tetanus
0.651 0.349 0.000
A34 Obstetrical tetanus
0.651 0.349 0.000
A33 Tetanus neonatorum
0.651 0.349 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.651 0.349 0.000
M81.8 Other osteoporosis
0.649 0.351 0.000
M81.6 Localised osteoporosis [Lequesne]
0.649 0.351 0.000
M81.5 Idiopathic osteoporosis
0.649 0.351 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.649 0.351 0.000
M81.2 Osteoporosis of disuse
0.649 0.351 0.000
M81.1 Postoophorectomy osteoporosis
0.649 0.351 0.000
M81.0 Postmenopausal osteoporosis
0.649 0.351 0.000
H55-H59 Other disorders of eye and adnexa
0.648 0.352 0.000
M81.4 Drug-induced osteoporosis
0.648 0.352 0.000
M79.62 Pain in limb (Upper arm)
0.648 0.352 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.648 0.352 0.000
M81.98 Osteoporosis, unspecified (Other)
0.647 0.353 0.000
M89 Other disorders of bone
0.647 0.353 0.000
Z96.8 Presence of other specified functional implants
0.647 0.353 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.646 0.353 0.000
M16.5 Other posttraumatic coxarthrosis
0.646 0.353 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.646 0.353 0.000
M16.3 Other dysplastic coxarthrosis
0.646 0.353 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.646 0.353 0.000
J31.2 Chronic pharyngitis
0.646 0.354 0.000
J31.1 Chronic nasopharyngitis
0.646 0.354 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.646 0.354 0.000
Y59 Other and unspecified vaccines and biological substances
0.646 0.354 0.000
Y58 Bacterial vaccines
0.646 0.354 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.646 0.354 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.646 0.354 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.646 0.354 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
Y48 Anaesthetics and therapeutic gases
0.646 0.354 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.646 0.354 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.646 0.354 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.645 0.355 0.000
Z10 Routine general health check-up of defined subpopulation
0.644 0.355 0.000
C16 Malignant neoplasm of stomach
0.644 0.355 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.644 0.356 0.000
Z96.7 Presence of other bone and tendon implants
0.644 0.356 0.000
Z80.3 Family history of malignant neoplasm of breast
0.643 0.357 0.000
W20-W49 Exposure to inanimate mechanical forces
0.642 0.358 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.642 0.358 0.000
U80 Agent resistant to penicillin and related antibiotics
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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