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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116369954
log Bayes Factor = 16.6039
Chromosome 10   position 114,793,572  (GRCh37) Explore rs116369954 on Ensembl!
Variant rs116369954 is part of Cluster X0226

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
E11.3 With ophthalmic complications
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.991 0.009 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.986 0.014 0.000
E10 Insulin-dependent diabetes mellitus
0.981 0.019 0.000
Chapter VIII Diseases of the ear and mastoid process
0.976 0.024 0.000
T39.1 4-Aminophenol derivatives
0.966 0.034 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.965 0.035 0.000
Chapter XIV Diseases of the genitourinary system
0.961 0.039 0.000
H43-H45 Disorders of vitreous body and globe
0.958 0.042 0.000
E10.9 Without complications
0.955 0.045 0.000
H53-H54 Visual disturbances and blindness
0.954 0.046 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.953 0.047 0.000
F30-F39 Mood [affective] disorders
0.949 0.051 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.946 0.054 0.000
N92 Excessive, frequent and irregular menstruation
0.942 0.058 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.929 0.071 0.000
Chapter II Neoplasms
0.927 0.073 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.926 0.074 0.000
H65-H75 Diseases of middle ear and mastoid
0.920 0.080 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.908 0.092 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.902 0.098 0.000
M20-M25 Other joint disorders
0.901 0.099 0.000
N80 Endometriosis
0.901 0.099 0.000
H90-H95 Other disorders of ear
0.900 0.100 0.000
Chapter IX Diseases of the circulatory system
0.894 0.106 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.893 0.107 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.887 0.113 0.000
N92.6 Irregular menstruation, unspecified
0.886 0.114 0.000
H43 Disorders of vitreous body
0.886 0.114 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.883 0.117 0.000
N10-N16 Renal tubulo-interstitial diseases
0.883 0.117 0.000
N92.4 Excessive bleeding in the premenopausal period
0.882 0.118 0.000
H30-H36 Disorders of choroid and retina
0.880 0.120 0.000
I20-I25 Ischaemic heart diseases
0.875 0.125 0.000
F33 Recurrent depressive disorder
0.873 0.127 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.872 0.128 0.000
M70-M79 Other soft tissue disorders
0.872 0.128 0.000
H65 Nonsuppurative otitis media
0.870 0.130 0.000
H54 Blindness and low vision
0.865 0.135 0.000
C51-C58 Malignant neoplasms of female genital organs
0.863 0.137 0.000
H53 Visual disturbances
0.860 0.140 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.859 0.141 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.858 0.142 0.000
F32 Depressive episode
0.857 0.143 0.000
T43.2 Other and unspecified antidepressants
0.857 0.143 0.000
F60-F69 Disorders of adult personality and behaviour
0.855 0.145 0.000
H44 Disorders of globe
0.852 0.148 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.851 0.149 0.000
I21 Acute myocardial infarction
0.850 0.150 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.849 0.151 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.848 0.152 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.846 0.154 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.845 0.155 0.000
M25 Other joint disorders, not elsewhere classified
0.843 0.157 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.839 0.161 0.000
Q80-Q89 Other congenital malformations
0.839 0.161 0.000
N00-N08 Glomerular diseases
0.834 0.166 0.000
E10.3 With ophthalmic complications
0.834 0.166 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.833 0.167 0.000
S50-S59 Injuries to the elbow and forearm
0.832 0.168 0.000
N80.0 Endometriosis of uterus
0.826 0.174 0.000
E11.8 With unspecified complications
0.826 0.174 0.000
H36 Retinal disorders in diseases classified elsewhere
0.822 0.178 0.000
H43.1 Vitreous haemorrhage
0.821 0.179 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.821 0.179 0.000
Q50-Q56 Congenital malformations of genital organs
0.815 0.184 0.000
M86-M90 Other osteopathies
0.814 0.186 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.814 0.186 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.814 0.186 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.813 0.187 0.000
H53.1 Subjective visual disturbances
0.809 0.191 0.000
H54.7 Unspecified visual loss
0.807 0.193 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.807 0.193 0.000
M24 Other specific joint derangements
0.805 0.195 0.000
T39.0 Salicylates
0.801 0.199 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.801 0.199 0.000
C79 Secondary malignant neoplasm of other sites
0.797 0.203 0.000
D80-D89 Certain disorders involving the immune mechanism
0.797 0.203 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.794 0.205 0.000
E10.0 With coma
0.794 0.206 0.000
M80-M85 Disorders of bone density and structure
0.794 0.206 0.000
H60-H62 Diseases of external ear
0.793 0.207 0.000
M75 Shoulder lesions
0.790 0.210 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.790 0.210 0.000
H93 Other disorders of ear, not elsewhere classified
0.788 0.212 0.000
H74 Other disorders of middle ear and mastoid
0.785 0.215 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.784 0.216 0.000
N71 Inflammatory disease of uterus, except cervix
0.783 0.217 0.000
H65.3 Chronic mucoid otitis media
0.782 0.218 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.781 0.219 0.000
H36.0 Diabetic retinopathy
0.781 0.219 0.000
E20-E35 Disorders of other endocrine glands
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.780 0.220 0.000
C91 Lymphoid leukaemia
0.779 0.221 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.778 0.222 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.777 0.223 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.777 0.223 0.000
E13 Other specified diabetes mellitus
0.776 0.224 0.000
Q21 Congenital malformations of cardiac septa
0.773 0.227 0.000
H53.9 Visual disturbance, unspecified
0.772 0.228 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.772 0.228 0.000
H43.3 Other vitreous opacities
0.770 0.230 0.000
T51 Toxic effect of alcohol
0.768 0.232 0.000
N83.0 Follicular cyst of ovary
0.767 0.233 0.000
H10-H13 Disorders of conjunctiva
0.766 0.234 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.765 0.235 0.000
N80.3 Endometriosis of pelvic peritoneum
0.765 0.235 0.000
N97 Female infertility
0.764 0.236 0.000
F99-F99 Unspecified mental disorder
0.764 0.236 0.000
F32.1 Moderate depressive episode
0.764 0.236 0.000
H17 Corneal scars and opacities
0.764 0.236 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.763 0.237 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.763 0.237 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.761 0.239 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.759 0.241 0.000
C54 Malignant neoplasm of corpus uteri
0.759 0.241 0.000
F80-F89 Disorders of psychological development
0.756 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.244 0.000
N92.5 Other specified irregular menstruation
0.756 0.244 0.000
H55-H59 Other disorders of eye and adnexa
0.755 0.244 0.000
C53 Malignant neoplasm of cervix uteri
0.755 0.244 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.755 0.245 0.000
T59 Toxic effect of other gases, fumes and vapours
0.755 0.245 0.000
I21.4 Acute subendocardial myocardial infarction
0.754 0.246 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.753 0.247 0.000
E14 Unspecified diabetes mellitus
0.752 0.248 0.000
N85.0 Endometrial glandular hyperplasia
0.752 0.248 0.000
C32 Malignant neoplasm of larynx
0.752 0.248 0.000
E11.4 With neurological complications
0.750 0.250 0.000
M22 Disorders of patella
0.750 0.250 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.750 0.250 0.000
M30 Polyarteritis nodosa and related conditions
0.748 0.252 0.000
H44.2 Degenerative myopia
0.747 0.253 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.747 0.253 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.746 0.254 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.746 0.254 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.744 0.256 0.000
E11.1 With ketoacidosis
0.743 0.256 0.000
T00-T07 Injuries involving multiple body regions
0.743 0.257 0.000
H33 Retinal detachments and breaks
0.742 0.258 0.000
M35 Other systemic involvement of connective tissue
0.741 0.259 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.740 0.260 0.000
N90.0 Mild vulvar dysplasia
0.738 0.262 0.000
D69 Purpura and other haemorrhagic conditions
0.738 0.262 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.735 0.265 0.000
N13 Obstructive and reflux uropathy
0.734 0.266 0.000
N90.4 Leukoplakia of vulva
0.733 0.267 0.000
S10-S19 Injuries to the neck
0.733 0.267 0.000
E40-E46 Malnutrition
0.732 0.267 0.000
H21 Other disorders of iris and ciliary body
0.732 0.268 0.000
H92 Otalgia and effusion of ear
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.731 0.269 0.000
S40-S49 Injuries to the shoulder and upper arm
0.731 0.269 0.000
N25-N29 Other disorders of kidney and ureter
0.731 0.269 0.000
H65.2 Chronic serous otitis media
0.729 0.271 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.728 0.272 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.728 0.272 0.000
N99-N99 Other disorders of the genitourinary system
0.727 0.273 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.727 0.273 0.000
H16 Keratitis
0.726 0.274 0.000
N82 Fistulae involving female genital tract
0.726 0.274 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.726 0.274 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.724 0.276 0.000
M75.1 Rotator cuff syndrome
0.724 0.276 0.000
H53.8 Other visual disturbances
0.721 0.279 0.000
N80.9 Endometriosis, unspecified
0.721 0.279 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
F60 Specific personality disorders
0.716 0.284 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.714 0.286 0.000
H72 Perforation of tympanic membrane
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.287 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.712 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.287 0.000
T36 Poisoning by systemic antibiotics
0.712 0.287 0.000
Q60-Q64 Congenital malformations of the urinary system
0.712 0.288 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.712 0.288 0.000
H52 Disorders of refraction and accommodation
0.712 0.288 0.000
F33.9 Recurrent depressive disorder, unspecified
0.711 0.289 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
Q28 Other congenital malformations of circulatory system
0.711 0.289 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.709 0.290 0.000
T39.4 Antirheumatics, not elsewhere classified
0.709 0.290 0.000
T39.2 Pyrazolone derivatives
0.709 0.290 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.709 0.291 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.709 0.291 0.000
H93.1 Tinnitus
0.708 0.292 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.708 0.292 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.708 0.292 0.000
C34 Malignant neoplasm of bronchus and lung
0.708 0.292 0.000
E10.5 With peripheral circulatory complications
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
H46 Optic neuritis
0.707 0.293 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.707 0.293 0.000
Q35-Q37 Cleft lip and cleft palate
0.707 0.293 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.707 0.293 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.705 0.295 0.000
E10.8 With unspecified complications
0.704 0.296 0.000
E10.7 With multiple complications
0.704 0.296 0.000
E10.6 With other specified complications
0.704 0.296 0.000
E10.4 With neurological complications
0.704 0.296 0.000
E10.2 With renal complications
0.704 0.296 0.000
T51.0 Ethanol
0.703 0.297 0.000
M25.9 Joint disorder, unspecified
0.701 0.299 0.000
C83.3 Large cell (diffuse)
0.698 0.302 0.000
M25.7 Osteophyte
0.697 0.303 0.000
E11.2 With renal complications
0.697 0.303 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.697 0.303 0.000
I22.8 Subsequent myocardial infarction of other sites
0.697 0.303 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.695 0.305 0.000
N87 Dysplasia of cervix uteri
0.694 0.306 0.000
H90 Conductive and sensorineural hearing loss
0.692 0.308 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.692 0.308 0.000
T43.9 Psychotropic drug, unspecified
0.692 0.308 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
T43.6 Psychostimulants with abuse potential
0.692 0.308 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.692 0.308 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.692 0.308 0.000
F64 Gender identity disorders
0.690 0.310 0.000
H61 Other disorders of external ear
0.688 0.312 0.000
D68 Other coagulation defects
0.688 0.312 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.687 0.313 0.000
M24.2 Disorder of ligament
0.687 0.313 0.000
C91.1 Chronic lymphocytic leukaemia
0.686 0.314 0.000
D50-D53 Nutritional anaemias
0.686 0.314 0.000
N90.7 Vulvar cyst
0.685 0.314 0.000
I60-I69 Cerebrovascular diseases
0.686 0.314 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.685 0.315 0.000
C54.1 Endometrium
0.684 0.316 0.000
N98 Complications associated with artificial fertilisation
0.683 0.317 0.000
N91 Absent, scanty and rare menstruation
0.683 0.317 0.000
N96 Habitual aborter
0.683 0.317 0.000
Chapter XXII Codes for special purposes
0.682 0.317 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.682 0.318 0.000
M72 Fibroblastic disorders
0.682 0.318 0.000
F38 Other mood [affective] disorders
0.680 0.320 0.000
F34 Persistent mood [affective] disorders
0.680 0.320 0.000
F30 Manic episode
0.680 0.320 0.000
F39 Unspecified mood [affective] disorder
0.680 0.320 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.680 0.320 0.000
N04 Nephrotic syndrome
0.680 0.320 0.000
Q85 Phakomatoses, not elsewhere classified
0.679 0.321 0.000
C53.9 Cervix uteri, unspecified
0.678 0.322 0.000
M00-M03 Infectious arthropathies
0.678 0.322 0.000
M84 Disorders of continuity of bone
0.677 0.323 0.000
H44.0 Purulent endophthalmitis
0.677 0.323 0.000
Q82 Other congenital malformations of skin
0.676 0.324 0.000
N92.2 Excessive menstruation at puberty
0.675 0.324 0.000
H54.0 Blindness, both eyes
0.674 0.326 0.000
F31 Bipolar affective disorder
0.673 0.326 0.000
I25 Chronic ischaemic heart disease
0.673 0.327 0.000
N05 Unspecified nephritic syndrome
0.673 0.327 0.000
C83.0 Small cell (diffuse)
0.673 0.327 0.000
S50 Superficial injury of forearm
0.672 0.328 0.000
M22.2 Patellofemoral disorders
0.672 0.328 0.000
N80.1 Endometriosis of ovary
0.671 0.329 0.000
Q43 Other congenital malformations of intestine
0.671 0.329 0.000
C51 Malignant neoplasm of vulva
0.670 0.330 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.669 0.331 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.669 0.331 0.000
H95.1 Other disorders following mastoidectomy
0.669 0.331 0.000
N86 Erosion and ectropion of cervix uteri
0.668 0.332 0.000
D00-D09 In situ neoplasms
0.668 0.332 0.000
H71 Cholesteatoma of middle ear
0.668 0.332 0.000
Chapter XX External causes of morbidity and mortality
0.668 0.332 0.000
Q23 Congenital malformations of aortic and mitral valves
0.667 0.333 0.000
Q21.1 Atrial septal defect
0.667 0.333 0.000
O00-O08 Pregnancy with abortive outcome
0.666 0.334 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.665 0.335 0.000
H17.9 Corneal scar and opacity, unspecified
0.664 0.336 0.000
H52.1 Myopia
0.663 0.337 0.000
I30-I52 Other forms of heart disease
0.663 0.337 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.338 0.000
N95 Menopausal and other perimenopausal disorders
0.662 0.338 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.660 0.340 0.000
N75 Diseases of Bartholin's gland
0.660 0.340 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.659 0.340 0.000
H70 Mastoiditis and related conditions
0.659 0.340 0.000
H68 Eustachian salpingitis and obstruction
0.659 0.340 0.000
H67 Otitis media in diseases classified elsewhere
0.659 0.340 0.000
S90-S99 Injuries to the ankle and foot
0.659 0.341 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.658 0.342 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.657 0.343 0.000
S52 Fracture of forearm
0.656 0.344 0.000
M91-M94 Chondropathies
0.655 0.344 0.000
T59.8 Other specified gases, fumes and vapours
0.655 0.345 0.000
E27 Other disorders of adrenal gland
0.655 0.345 0.000
F32.9 Depressive episode, unspecified
0.655 0.345 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.655 0.345 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.653 0.347 0.000
M21 Other acquired deformities of limbs
0.652 0.348 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.651 0.349 0.000
C95 Leukaemia of unspecified cell type
0.651 0.349 0.000
C94 Other leukaemias of specified cell type
0.651 0.349 0.000
C93 Monocytic leukaemia
0.651 0.349 0.000
C88 Malignant immunoproliferative diseases
0.651 0.349 0.000
C86 Other specified types of T/NK-cell lymphoma
0.651 0.349 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.651 0.349 0.000
C81 Hodgkin's disease
0.651 0.349 0.000
C32.9 Larynx, unspecified
0.651 0.349 0.000
E11.5 With peripheral circulatory complications
0.651 0.349 0.000
M34 Systemic sclerosis
0.650 0.350 0.000
T17 Foreign body in respiratory tract
0.648 0.352 0.000
D66 Hereditary factor VIII deficiency
0.647 0.353 0.000
M15-M19 Arthrosis
0.647 0.353 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.647 0.353 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.647 0.353 0.000
H15 Disorders of sclera
0.647 0.353 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.646 0.354 0.000
M33 Dermatopolymyositis
0.646 0.354 0.000
M32 Systemic lupus erythematosus
0.646 0.354 0.000
N80.6 Endometriosis in cutaneous scar
0.646 0.354 0.000
N80.5 Endometriosis of intestine
0.646 0.354 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.646 0.354 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.645 0.354 0.000
M25.0 Haemarthrosis
0.645 0.355 0.000
C73 Malignant neoplasm of thyroid gland
0.645 0.355 0.000
H57 Other disorders of eye and adnexa
0.644 0.356 0.000
N10 Acute tubulo-interstitial nephritis
0.644 0.356 0.000
Q65 Congenital deformities of hip
0.644 0.356 0.000
H20 Iridocyclitis
0.644 0.356 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.643 0.357 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.643 0.357 0.000
I00-I02 Acute rheumatic fever
0.641 0.359 0.000
T65 Toxic effect of other and unspecified substances
0.640 0.359 0.000
T62 Toxic effect of other noxious substances eaten as food
0.640 0.359 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.640 0.359 0.000
T60 Toxic effect of pesticides
0.640 0.359 0.000
T57 Toxic effect of other inorganic substances
0.640 0.359 0.000
T56 Toxic effect of metals
0.640 0.359 0.000
T54 Toxic effect of corrosive substances
0.640 0.359 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.640 0.359 0.000
T52 Toxic effect of organic solvents
0.640 0.359 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.640 0.359 0.000
T58 Toxic effect of carbon monoxide
0.640 0.359 0.000
T55 Toxic effect of soaps and detergents
0.640 0.359 0.000
M88 Paget's disease of bone [osteitis deformans]
0.640 0.360 0.000
M71 Other bursopathies
0.639 0.361 0.000
H69 Other disorders of Eustachian tube
0.639 0.361 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.639 0.361 0.000
M35.3 Polymyalgia rheumatica
0.638 0.362 0.000
M25.3 Other instability of joint
0.638 0.362 0.000
M90 Osteopathies in diseases classified elsewhere
0.637 0.363 0.000
M89 Other disorders of bone
0.637 0.363 0.000
I05-I09 Chronic rheumatic heart diseases
0.637 0.363 0.000
H50 Other strabismus
0.636 0.364 0.000
M75.3 Calcific tendinitis of shoulder
0.636 0.364 0.000
Q27 Other congenital malformations of peripheral vascular system
0.636 0.364 0.000
Q26 Congenital malformations of great veins
0.636 0.364 0.000
Q25 Congenital malformations of great arteries
0.636 0.364 0.000
Q24 Other congenital malformations of heart
0.636 0.364 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.636 0.364 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.636 0.364 0.000
N85.6 Intra-uterine synechiae
0.636 0.364 0.000
N02 Recurrent and persistent haematuria
0.636 0.364 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.636 0.364 0.000
M77 Other enthesopathies
0.635 0.365 0.000
H43.9 Disorder of vitreous body, unspecified
0.635 0.365 0.000
H43.2 Crystalline deposits in vitreous body
0.635 0.365 0.000
H43.0 Vitreous prolapse
0.635 0.365 0.000
T79-T79 Certain early complications of trauma
0.635 0.365 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.634 0.366 0.000
T63 Toxic effect of contact with venomous animals
0.634 0.366 0.000
N90.6 Hypertrophy of vulva
0.633 0.367 0.000
N90.3 Dysplasia of vulva, unspecified
0.633 0.367 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.633 0.367 0.000
N90.1 Moderate vulvar dysplasia
0.633 0.367 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.633 0.367 0.000
N15 Other renal tubulo-interstitial diseases
0.633 0.367 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.633 0.367 0.000
N11 Chronic tubulo-interstitial nephritis
0.633 0.367 0.000
M25.8 Other specified joint disorders
0.633 0.367 0.000
M25.78 Osteophyte (Other)
0.633 0.367 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.632 0.368 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.631 0.369 0.000
H31 Other disorders of choroid
0.631 0.369 0.000
H30 Chorioretinal inflammation
0.631 0.369 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.631 0.369 0.000
M85 Other disorders of bone density and structure
0.631 0.369 0.000
H18 Other disorders of cornea
0.630 0.369 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.630 0.370 0.000
N83.1 Corpus luteum cyst
0.630 0.370 0.000
M75.5 Bursitis of shoulder
0.629 0.371 0.000
N97.9 Female infertility, unspecified
0.629 0.371 0.000
I47 Paroxysmal tachycardia
0.628 0.372 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.628 0.372 0.000
N70 Salpingitis and oophoritis
0.628 0.372 0.000
I23 Certain current complications following acute myocardial infarction
0.627 0.373 0.000
Y43 Primarily systemic agents
0.627 0.373 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.627 0.373 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.627 0.373 0.000
F33.8 Other recurrent depressive disorders
0.626 0.374 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.626 0.374 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.626 0.374 0.000
F43 Reaction to severe stress, and adjustment disorders
0.626 0.374 0.000
M76 Enthesopathies of lower limb, excluding foot
0.625 0.375 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.625 0.375 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.625 0.375 0.000
H65.1 Other acute nonsuppurative otitis media
0.623 0.376 0.000
H65.0 Acute serous otitis media
0.623 0.376 0.000
H33.3 Retinal breaks without detachment
0.623 0.377 0.000
N03 Chronic nephritic syndrome
0.623 0.377 0.000
Q54 Hypospadias
0.623 0.377 0.000
E14.9 Without complications
0.622 0.378 0.000
H49 Paralytic strabismus
0.621 0.379 0.000
H54.6 Unqualified visual loss, one eye
0.620 0.379 0.000
H54.5 Low vision, one eye
0.620 0.379 0.000
H54.3 Unqualified visual loss, both eyes
0.620 0.379 0.000
H54.2 Low vision, both eyes
0.620 0.379 0.000
H54.1 Blindness, one eye, low vision, other eye
0.620 0.379 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.619 0.381 0.000
C58 Malignant neoplasm of placenta
0.619 0.381 0.000
C52 Malignant neoplasm of vagina
0.619 0.381 0.000
Y43.3 Other antineoplastic drugs
0.618 0.382 0.000
H53.6 Night blindness
0.616 0.384 0.000
H53.5 Colour vision deficiencies
0.616 0.384 0.000
H53.3 Other disorders of binocular vision
0.616 0.384 0.000
C34.9 Bronchus or lung, unspecified
0.616 0.384 0.000
C82.6 Cutaneous follicle centre lymphoma
0.616 0.384 0.000
C82.5 Diffuse follicle centre lymphoma
0.616 0.384 0.000
C82.4 Follicular lymphoma grade IIIb
0.616 0.384 0.000
C82.3 Follicular lymphoma grade IIIa
0.616 0.384 0.000
C82.2 Large cell, follicular
0.616 0.384 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.616 0.384 0.000
C82.0 Small cleaved cell, follicular
0.616 0.384 0.000
I25.2 Old myocardial infarction
0.615 0.385 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.615 0.385 0.000
E13.9 Without complications
0.615 0.385 0.000
N13.8 Other obstructive and reflux uropathy
0.615 0.385 0.000
F32.8 Other depressive episodes
0.615 0.385 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.614 0.386 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.613 0.387 0.000
I60 Subarachnoid haemorrhage
0.613 0.387 0.000
F68 Other disorders of adult personality and behaviour
0.613 0.387 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.613 0.387 0.000
F65 Disorders of sexual preference
0.613 0.387 0.000
F63 Habit and impulse disorders
0.613 0.387 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.613 0.387 0.000
F69 Unspecified disorder of adult personality and behaviour
0.613 0.387 0.000
F61 Mixed and other personality disorders
0.613 0.387 0.000
H61.2 Impacted cerumen
0.613 0.387 0.000
M24.0 Loose body in joint
0.611 0.389 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.611 0.389 0.000
H44.9 Disorder of globe, unspecified
0.611 0.389 0.000
H44.8 Other disorders of globe
0.611 0.389 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.611 0.389 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.611 0.389 0.000
H44.5 Degenerated conditions of globe
0.611 0.389 0.000
H44.4 Hypotony of eye
0.611 0.389 0.000
H44.3 Other degenerative disorders of globe
0.611 0.389 0.000
H44.1 Other endophthalmitis
0.611 0.389 0.000
M24.1 Other articular cartilage disorders
0.611 0.389 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.609 0.390 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.609 0.390 0.000
Q45 Other congenital malformations of digestive system
0.608 0.391 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.608 0.391 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.608 0.391 0.000
Q40 Other congenital malformations of upper alimentary tract
0.608 0.391 0.000
Q39 Congenital malformations of oesophagus
0.608 0.391 0.000
H54.9 Unspecified visual impairment (binocular)
0.609 0.391 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.608 0.392 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.608 0.392 0.000
C31 Malignant neoplasm of accessory sinuses
0.608 0.392 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.608 0.392 0.000
C37 Malignant neoplasm of thymus
0.608 0.392 0.000
C33 Malignant neoplasm of trachea
0.608 0.392 0.000
D69.6 Thrombocytopenia, unspecified
0.608 0.392 0.000
D68.9 Coagulation defect, unspecified
0.608 0.392 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.607 0.393 0.000
D67 Hereditary factor IX deficiency
0.607 0.393 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.607 0.393 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.607 0.393 0.000
H51 Other disorders of binocular movement
0.606 0.394 0.000
M19 Other arthrosis
0.606 0.394 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.606 0.394 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.606 0.394 0.000
S51 Open wound of forearm
0.606 0.394 0.000
C32.0 Glottis
0.606 0.394 0.000
D70 Agranulocytosis
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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