TreeWAS – Variant ID: rs116375068

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.994	0.006
E10-E14 Diabetes mellitus	0.986	0.014
M20-M25 Other joint disorders	0.982	0.018
T36-T50 Poisoning by drugs, medicaments and biological substances	0.980	0.020
Chapter II Neoplasms	0.974	0.026
Chapter XIV Diseases of the genitourinary system	0.958	0.042
E00-E07 Disorders of thyroid gland	0.956	0.044
Chapter XV Pregnancy, childbirth and the puerperium	0.952	0.048
M70-M79 Other soft tissue disorders	0.942	0.058
M20 Acquired deformities of fingers and toes	0.941	0.059
N40-N51 Diseases of male genital organs	0.940	0.060
E14 Unspecified diabetes mellitus	0.933	0.067
D10-D36 Benign neoplasms	0.932	0.068
E10 Insulin-dependent diabetes mellitus	0.926	0.074
Chapter VIII Diseases of the ear and mastoid process	0.920	0.080
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.910	0.090
E03 Other hypothyroidism	0.901	0.099
E14.9 Without complications	0.895	0.105
Chapter V Mental and behavioural disorders	0.892	0.108
M23 Internal derangement of knee	0.891	0.109
C60-C63 Malignant neoplasms of male genital organs	0.890	0.109
M79 Other soft tissue disorders, not elsewhere classified	0.878	0.122
N60-N64 Disorders of breast	0.878	0.122
N41 Inflammatory diseases of prostate	0.868	0.132
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.868	0.132
S70-S79 Injuries to the hip and thigh	0.867	0.133
E03.9 Hypothyroidism, unspecified	0.863	0.137
D17 Benign lipomatous neoplasm	0.860	0.140
Chapter VI Diseases of the nervous system	0.857	0.143
D00-D09 In situ neoplasms	0.855	0.145
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.852	0.148
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.847	0.153
D37-D48 Neoplasms of uncertain or unknown behaviour	0.844	0.156
M05-M14 Inflammatory polyarthropathies	0.842	0.158
M23.2 Derangement of meniscus due to old tear or injury	0.841	0.159
Chapter VII Diseases of the eye and adnexa	0.838	0.162
E10.9 Without complications	0.838	0.162
S40-S49 Injuries to the shoulder and upper arm	0.836	0.164
C61 Malignant neoplasm of prostate	0.831	0.169
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.829	0.171
T39.1 4-Aminophenol derivatives	0.824	0.176
S80-S89 Injuries to the knee and lower leg	0.820	0.180
D22 Melanocytic naevi	0.818	0.182
M20.1 Hallux valgus (acquired)	0.817	0.183
H90-H95 Other disorders of ear	0.812	0.188
E05 Thyrotoxicosis [hyperthyroidism]	0.810	0.190
N41.1 Chronic prostatitis	0.810	0.190
D23 Other benign neoplasms of skin	0.805	0.195
M20.5 Other deformities of toe(s) (acquired)	0.803	0.197
M20.4 Other hammer toe(s) (acquired)	0.798	0.201
E10.3 With ophthalmic complications	0.798	0.202
O94-O99 Other obstetric conditions, not elsewhere classified	0.796	0.204
M22 Disorders of patella	0.795	0.205
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.795	0.205
N48 Other disorders of penis	0.794	0.206
N63 Unspecified lump in breast	0.786	0.214
F10 Mental and behavioural disorders due to use of alcohol	0.785	0.215
O60-O75 Complications of labour and delivery	0.781	0.219
S60-S69 Injuries to the wrist and hand	0.781	0.219
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.777	0.222
H30-H36 Disorders of choroid and retina	0.777	0.223
C64-C68 Malignant neoplasms of urinary tract	0.776	0.224
N40 Hyperplasia of prostate	0.776	0.224
S72 Fracture of femur	0.773	0.227
E11 Non-insulin-dependent diabetes mellitus	0.773	0.227
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.770	0.230
M79.8 Other specified soft tissue disorders	0.768	0.232
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.768	0.232
D34 Benign neoplasm of thyroid gland	0.767	0.233
N70-N77 Inflammatory diseases of female pelvic organs	0.767	0.233
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.758	0.242
H80-H83 Diseases of inner ear	0.758	0.242
Chapter I Certain infectious and parasitic diseases	0.758	0.242
M72 Fibroblastic disorders	0.757	0.243
S00-S09 Injuries to the head	0.757	0.243
N47 Redundant prepuce, phimosis and paraphimosis	0.757	0.243
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.757	0.243
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.753	0.247
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.753	0.247
S90-S99 Injuries to the ankle and foot	0.752	0.248
M20.3 Other deformity of hallux (acquired)	0.752	0.248
Chapter XII Diseases of the skin and subcutaneous tissue	0.751	0.249
N10-N16 Renal tubulo-interstitial diseases	0.749	0.251
M21 Other acquired deformities of limbs	0.748	0.252
M06 Other rheumatoid arthritis	0.743	0.257
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.738	0.262
D18 Haemangioma and lymphangioma, any site	0.737	0.263
O36 Maternal care for other known or suspected foetal problems	0.736	0.264
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.735	0.265
T66-T78 Other and unspecified effects of external causes	0.732	0.268
D07 Carcinoma in situ of other and unspecified genital organs	0.731	0.269
G40-G47 Episodic and paroxysmal disorders	0.729	0.271
M77 Other enthesopathies	0.728	0.272
E50-E64 Other nutritional deficiencies	0.727	0.272
Chapter IX Diseases of the circulatory system	0.722	0.278
M86-M90 Other osteopathies	0.722	0.278
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.722	0.278
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.720	0.280
S42 Fracture of shoulder and upper arm	0.720	0.280
D32 Benign neoplasm of meninges	0.720	0.280
M79.0 Rheumatism, unspecified	0.720	0.280
D35 Benign neoplasm of other and unspecified endocrine glands	0.718	0.282
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M40-M43 Deforming dorsopathies	0.716	0.284
T42.4 Benzodiazepines	0.715	0.285
E40-E46 Malnutrition	0.715	0.285
E20-E35 Disorders of other endocrine glands	0.715	0.285
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.715	0.285
T79-T79 Certain early complications of trauma	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.285
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
S10-S19 Injuries to the neck	0.715	0.285
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.715	0.285
D22.5 Melanocytic naevi of trunk	0.715	0.285
N43 Hydrocele and spermatocele	0.714	0.286
N25-N29 Other disorders of kidney and ureter	0.714	0.286
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.712	0.288
M91-M94 Chondropathies	0.712	0.288
M60-M63 Disorders of muscles	0.712	0.288
M00-M03 Infectious arthropathies	0.712	0.288
F10.3 Withdrawal state	0.711	0.289
E70-E90 Metabolic disorders	0.711	0.289
O42 Premature rupture of membranes	0.711	0.289
T43.5 Other and unspecified antipsychotics and neuroleptics	0.709	0.291
N99-N99 Other disorders of the genitourinary system	0.709	0.291
E13 Other specified diabetes mellitus	0.707	0.293
E12 Malnutrition-related diabetes mellitus	0.707	0.293
M24 Other specific joint derangements	0.706	0.294
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.704	0.296
M34 Systemic sclerosis	0.704	0.296
M33 Dermatopolymyositis	0.704	0.296
M32 Systemic lupus erythematosus	0.704	0.296
M31 Other necrotising vasculopathies	0.704	0.296
M30 Polyarteritis nodosa and related conditions	0.704	0.296
D22.7 Melanocytic naevi of lower limb, including hip	0.703	0.297
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.703	0.297
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.703	0.297
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.703	0.297
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.703	0.297
T46 Poisoning by agents primarily affecting the cardiovascular system	0.703	0.297
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.703	0.297
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.703	0.297
T41 Poisoning by anaesthetics and therapeutic gases	0.703	0.297
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.703	0.297
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.703	0.297
T36 Poisoning by systemic antibiotics	0.703	0.297
M79.6 Pain in limb	0.702	0.298
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.701	0.299
M35 Other systemic involvement of connective tissue	0.701	0.299
H65-H75 Diseases of middle ear and mastoid	0.699	0.301
N61 Inflammatory disorders of breast	0.699	0.301
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.698	0.302
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.698	0.302
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.698	0.302
C40-C41 Malignant neoplasms of bone and articular cartilage	0.698	0.302
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.698	0.302
D45 Polycythaemia vera	0.698	0.302
O20-O29 Other maternal disorders predominantly related to pregnancy	0.694	0.306
T43.2 Other and unspecified antidepressants	0.693	0.307
T43.0 Tricyclic and tetracyclic antidepressants	0.693	0.307
S82 Fracture of lower leg, including ankle	0.693	0.307
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.689	0.311
E05.9 Thyrotoxicosis, unspecified	0.689	0.311
H93 Other disorders of ear, not elsewhere classified	0.688	0.311
S20-S29 Injuries to the thorax	0.686	0.314
E07 Other disorders of thyroid	0.685	0.315
E06 Thyroiditis	0.685	0.315
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.685	0.315
E00 Congenital iodine-deficiency syndrome	0.685	0.315
E02 Subclinical iodine-deficiency hypothyroidism	0.685	0.315
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.684	0.316
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.684	0.316
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.683	0.317
N50 Other disorders of male genital organs	0.683	0.317
O85-O92 Complications predominantly related to the puerperium	0.683	0.317
E65-E68 Obesity and other hyperalimentation	0.682	0.318
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.680	0.320
H35 Other retinal disorders	0.680	0.320
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.679	0.320
N00-N08 Glomerular diseases	0.677	0.323
E04 Other non-toxic goitre	0.677	0.323
I70-I79 Diseases of arteries, arterioles and capillaries	0.677	0.323
M25 Other joint disorders, not elsewhere classified	0.675	0.325
M76 Enthesopathies of lower limb, excluding foot	0.675	0.325
M73 Soft tissue disorders in diseases classified elsewhere	0.675	0.325
M71 Other bursopathies	0.675	0.325
M70 Soft tissue disorders related to use, overuse and pressure	0.675	0.325
M20.6 Acquired deformity of toe(s), unspecified	0.675	0.325
M20.0 Deformity of finger(s)	0.675	0.325
N51 Disorders of male genital organs in diseases classified elsewhere	0.674	0.326
N46 Male infertility	0.674	0.326
N44 Torsion of testis	0.674	0.326
D23.0 Skin of lip	0.672	0.328
S72.0 Fracture of neck of femur	0.671	0.329
E14.8 With unspecified complications	0.669	0.331
E14.7 With multiple complications	0.669	0.331
E14.6 With other specified complications	0.669	0.331
E14.5 With peripheral circulatory complications	0.669	0.331
E14.4 With neurological complications	0.669	0.331
E14.3 With ophthalmic complications	0.669	0.331
E14.2 Withrenal complications	0.669	0.331
E14.1 With ketoacidosis	0.669	0.331
E14.0 With coma	0.669	0.331
D36 Benign neoplasm of other and unspecified sites	0.668	0.331
D33 Benign neoplasm of brain and other parts of central nervous system	0.668	0.331
D31 Benign neoplasm of eye and adnexa	0.668	0.331
D30 Benign neoplasm of urinary organs	0.668	0.331
D29 Benign neoplasm of male genital organs	0.668	0.331
D28 Benign neoplasm of other and unspecified female genital organs	0.668	0.331
D26 Other benign neoplasms of uterus	0.668	0.331
D21 Other benign neoplasms of connective and other soft tissue	0.668	0.331
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.668	0.331
D19 Benign neoplasm of mesothelial tissue	0.668	0.331
D16 Benign neoplasm of bone and articular cartilage	0.668	0.331
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.668	0.331
D14 Benign neoplasm of middle ear and respiratory system	0.668	0.331
D11 Benign neoplasm of major salivary glands	0.668	0.331
D10 Benign neoplasm of mouth and pharynx	0.668	0.331
H36 Retinal disorders in diseases classified elsewhere	0.668	0.332
H91 Other hearing loss	0.667	0.333
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.664	0.336
E10.8 With unspecified complications	0.664	0.336
E10.7 With multiple complications	0.664	0.336
E10.6 With other specified complications	0.664	0.336
E10.5 With peripheral circulatory complications	0.664	0.336
E10.4 With neurological complications	0.664	0.336
E10.2 With renal complications	0.664	0.336
E10.1 With ketoacidosis	0.664	0.336
E10.0 With coma	0.664	0.336
N20-N23 Urolithiasis	0.662	0.338
M75 Shoulder lesions	0.662	0.338
N60 Benign mammary dysplasia	0.662	0.338
G90-G99 Other disorders of the nervous system	0.660	0.340
H60-H62 Diseases of external ear	0.660	0.340
S50-S59 Injuries to the elbow and forearm	0.659	0.341
O69 Labour and delivery complicated by umbilical cord complications	0.659	0.341
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.658	0.342
F10.2 Dependence syndrome	0.657	0.343
O36.8 Maternal care for other specified foetal problems	0.656	0.344
M05 Seropositive rheumatoid arthritis	0.656	0.344
Chapter XX External causes of morbidity and mortality	0.654	0.346
M79.86 Other specified soft tissue disorders (Lower leg)	0.654	0.346
G30-G32 Other degenerative diseases of the nervous system	0.653	0.347
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.652	0.348
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.652	0.348
T39.4 Antirheumatics, not elsewhere classified	0.652	0.348
T39.2 Pyrazolone derivatives	0.652	0.348
T39.0 Salicylates	0.652	0.348
D03 Melanoma in situ	0.652	0.348
O00-O08 Pregnancy with abortive outcome	0.652	0.348
N41.9 Inflammatory disease of prostate, unspecified	0.651	0.348
H53-H54 Visual disturbances and blindness	0.651	0.349
F30-F39 Mood [affective] disorders	0.651	0.349
M80-M85 Disorders of bone density and structure	0.650	0.349
D05 Carcinoma in situ of breast	0.649	0.351
L00-L08 Infections of the skin and subcutaneous tissue	0.649	0.351
M06.9 Rheumatoid arthritis, unspecified	0.648	0.352
N17-N19 Renal failure	0.648	0.352
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.647	0.353
E03.8 Other specified hypothyroidism	0.646	0.354
E03.5 Myxoedema coma	0.646	0.354
E03.4 Atrophy of thyroid (acquired)	0.646	0.354
E03.3 Postinfectious hypothyroidism	0.646	0.354
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.646	0.354
E03.1 Congenital hypothyroidism without goitre	0.646	0.354
E03.0 Congenital hypothyroidism with diffuse goitre	0.646	0.354
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.646	0.354
M79.7 Fibromyalgia	0.646	0.354
M15-M19 Arthrosis	0.645	0.355
S01 Open wound of head	0.645	0.355
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.644	0.356
G50-G59 Nerve, nerve root and plexus disorders	0.642	0.358
D07.5 Prostate	0.642	0.358
M23.8 Other internal derangements of knee	0.641	0.358
F99-F99 Unspecified mental disorder	0.640	0.360
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.640	0.360
F80-F89 Disorders of psychological development	0.640	0.360
F70-F79 Mental retardation	0.640	0.360
F60-F69 Disorders of adult personality and behaviour	0.640	0.360
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.640	0.360
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.640	0.360
F00-F09 Organic, including symptomatic, mental disorders	0.640	0.360
O80-O84 Delivery	0.639	0.360
M23.9 Internal derangement of knee, unspecified	0.639	0.361
M23.6 Other spontaneous disruption of ligament(s) of knee	0.639	0.361
M23.5 Chronic instability of knee	0.639	0.361
M23.4 Loose body in knee	0.639	0.361
M23.1 Discoid meniscus (congenital)	0.639	0.361
M23.0 Cystic meniscus	0.639	0.361
M65-M68 Disorders of synovium and tendon	0.639	0.361
C63 Malignant neoplasm of other and unspecified male genital organs	0.638	0.361
C62 Malignant neoplasm of testis	0.638	0.361
C60 Malignant neoplasm of penis	0.638	0.361
O16 Unspecified maternal hypertension	0.636	0.364
O32 Maternal care for known or suspected malpresentation of foetus	0.634	0.366
B35-B49 Mycoses	0.633	0.367
N48.4 Impotence of organic origin	0.632	0.368
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.632	0.368
H43-H45 Disorders of vitreous body and globe	0.632	0.368
D22.4 Melanocytic naevi of scalp and neck	0.631	0.369
F10.1 Harmful use	0.630	0.369
G80-G83 Cerebral palsy and other paralytic syndromes	0.630	0.370
S72.2 Subtrochanteric fracture	0.630	0.370
M22.8 Other disorders of patella	0.629	0.370
D24 Benign neoplasm of breast	0.629	0.371
M79.9 Soft tissue disorder, unspecified	0.629	0.371
M79.5 Residual foreign body in soft tissue	0.629	0.371
M79.4 Hypertrophy of (infrapatellar) fat pad	0.629	0.371
M79.3 Panniculitis, unspecified	0.629	0.371
M79.2 Neuralgia and neuritis, unspecified	0.629	0.371
M79.1 Myalgia	0.629	0.371
N64 Other disorders of breast	0.629	0.371
C51-C58 Malignant neoplasms of female genital organs	0.629	0.371
N72 Inflammatory disease of cervix uteri	0.629	0.371
N62 Hypertrophy of breast	0.628	0.372
N45 Orchitis and epididymitis	0.627	0.373
M50-M54 Other dorsopathies	0.626	0.374
M20.2 Hallux rigidus	0.626	0.374
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.625	0.374
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.625	0.375
D23.3 Skin of other and unspecified parts of face	0.624	0.376
D06 Carcinoma in situ of cervix uteri	0.623	0.377
N41.8 Other inflammatory diseases of prostate	0.622	0.378
N41.3 Prostatocystitis	0.622	0.378
N41.2 Abscess of prostate	0.622	0.378
N41.0 Acute prostatitis	0.622	0.378
T43.9 Psychotropic drug, unspecified	0.622	0.378
T43.8 Other psychotropic drugs, not elsewhere classified	0.622	0.378
T43.6 Psychostimulants with abuse potential	0.622	0.378
T43.4 Butyrophenone and thioxanthene neuroleptics	0.622	0.378
T43.3 Phenothiazine antipsychotics and neuroleptics	0.622	0.378
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.622	0.378
C64 Malignant neoplasm of kidney, except renal pelvis	0.622	0.378
E11.3 With ophthalmic complications	0.622	0.378
S79 Other and unspecified injuries of hip and thigh	0.622	0.378
S78 Traumatic amputation of hip and thigh	0.622	0.378
S77 Crushing injury of hip and thigh	0.622	0.378
S76 Injury of muscle and tendon at hip and thigh level	0.622	0.378
S75 Injury of blood vessels at hip and thigh level	0.622	0.378
S74 Injury of nerves at hip and thigh level	0.622	0.378
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.622	0.378
S71 Open wound of hip and thigh	0.622	0.378
S70 Superficial injury of hip and thigh	0.622	0.378
N48.6 Balanitis xerotica obliterans	0.621	0.379
N42 Other disorders of prostate	0.621	0.379
S32 Fracture of lumbar spine and pelvis	0.620	0.380
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.619	0.380
M79.84 Other specified soft tissue disorders (Hand)	0.619	0.381
N49.2 Inflammatory disorders of scrotum	0.619	0.381
D70-D77 Other diseases of blood and blood-forming organs	0.619	0.381
D17.9 Benign lipomatous neoplasm, unspecified	0.617	0.383
D17.7 Benign lipomatous neoplasm of other sites	0.617	0.383
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.617	0.383
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.617	0.383
O34 Maternal care for known or suspected abnormality of pelvic organs	0.617	0.383
G70-G73 Diseases of myoneural junction and muscle	0.614	0.386
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.614	0.386
G00-G09 Inflammatory diseases of the central nervous system	0.614	0.386
Chapter XXI Factors influencing health status and contact with health services	0.614	0.386
O73 Retained placenta and membranes, without haemorrhage	0.613	0.387
D09 Carcinoma in situ of other and unspecified sites	0.613	0.387
D04 Carcinoma in situ of skin	0.613	0.387
D02 Carcinoma in situ of middle ear and respiratory system	0.613	0.387
D01 Carcinoma in situ of other and unspecified digestive organs	0.613	0.387
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.613	0.387
E05.0 Thyrotoxicosis with diffuse goitre	0.612	0.388
A30-A49 Other bacterial diseases	0.612	0.388
M22.4 Chondromalacia patellae	0.612	0.388
N48.1 Balanoposthitis	0.612	0.388
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.611	0.389
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.611	0.389
T42.5 Mixed antiepileptics, not elsewhere classified	0.611	0.389
T42.3 Barbiturates	0.611	0.389
T42.2 Succinimides and oxazolidinediones	0.611	0.389
T42.1 Iminostilbenes	0.611	0.389
T42.0 Hydantoin derivatives	0.611	0.389
H02 Other disorders of eyelid	0.611	0.389
O47 False labour	0.607	0.392
O45 Premature separation of placenta [abruptio placentae]	0.607	0.392
O44 Placenta praevia	0.607	0.392
O43 Placental disorders	0.607	0.392
O41 Other disorders of amniotic fluid and membranes	0.607	0.392
O35 Maternal care for known or suspected foetal abnormality and damage	0.607	0.392
O33 Maternal care for known or suspected disproportion	0.607	0.392
O31 Complications specific to multiple gestation	0.607	0.392
O30 Multiple gestation	0.607	0.392
O40 Polyhydramnios	0.607	0.392
M10 Gout	0.606	0.393
M79.66 Pain in limb (Lower leg)	0.605	0.394
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.605	0.395
D46 Myelodysplastic syndromes	0.605	0.395
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.605	0.395
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.605	0.395
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.605	0.395
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.605	0.395
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.605	0.395
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.605	0.395
M14 Arthropathies in other diseases classified elsewhere	0.604	0.396
M12 Other specific arthropathies	0.604	0.396
M11 Other crystal arthropathies	0.604	0.396
M09 Juvenile arthritis in diseases classified elsewhere	0.604	0.396
M08 Juvenile arthritis	0.604	0.396
M07 Psoriatic and enteropathic arthropathies	0.604	0.396
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.603	0.397
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.603	0.397
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.603	0.397
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.603	0.397
G40 Epilepsy	0.603	0.397
E16 Other disorders of pancreatic internal secretion	0.603	0.397
S62 Fracture at wrist and hand level	0.602	0.398
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.602	0.398
D23.6 Skin of upper limb, including shoulder	0.601	0.399
H55-H59 Other disorders of eye and adnexa	0.601	0.399
H46-H48 Disorders of optic nerve and visual pathways	0.601	0.399
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.601	0.399
H10-H13 Disorders of conjunctiva	0.601	0.399
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.601	0.399
H93.1 Tinnitus	0.600	0.400
S49 Other and unspecified injuries of shoulder and upper arm	0.599	0.400
S48 Traumatic amputation of shoulder and upper arm	0.599	0.400
S46 Injury of muscle and tendon at shoulder and upper arm level	0.599	0.400
S45 Injury of blood vessels at shoulder and upper arm level	0.599	0.400
S44 Injury of nerves at shoulder and upper arm level	0.599	0.400
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.599	0.400
S41 Open wound of shoulder and upper arm	0.599	0.400
S40 Superficial injury of shoulder and upper arm	0.599	0.400
S47 Crushing injury of shoulder and upper arm	0.599	0.400
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.599	0.401
S72.00 Fracture of neck of femur (closed)	0.598	0.402
D18.0 Haemangioma, any site	0.597	0.403
E89.0 Postprocedural hypothyroidism	0.596	0.404
S42.0 Fracture of clavicle	0.596	0.404
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.594	0.406
F18 Mental and behavioural disorders due to use of volatile solvents	0.594	0.406
F16 Mental and behavioural disorders due to use of hallucinogens	0.594	0.406
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.594	0.406
F14 Mental and behavioural disorders due to use of cocaine	0.594	0.406
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.594	0.406
F12 Mental and behavioural disorders due to use of cannabinoids	0.594	0.406
F11 Mental and behavioural disorders due to use of opioids	0.594	0.406
H80 Otosclerosis	0.593	0.407
D23.1 Skin of eyelid, including canthus	0.592	0.408
C50-C50 Malignant neoplasm of breast	0.592	0.408
G45 Transient cerebral ischaemic attacks and related syndromes	0.592	0.408
E83 Disorders of mineral metabolism	0.591	0.409
H36.0 Diabetic retinopathy	0.590	0.410
E11.5 With peripheral circulatory complications	0.590	0.410
O68 Labour and delivery complicated by foetal stress [distress]	0.589	0.411
O42.9 Premature rupture of membranes, unspecified	0.588	0.411
S89 Other and unspecified injuries of lower leg	0.588	0.412
S88 Traumatic amputation of lower leg	0.588	0.412
S87 Crushing injury of lower leg	0.588	0.412
S86 Injury of muscle and tendon at lower leg level	0.588	0.412
S85 Injury of blood vessels at lower leg level	0.588	0.412
S84 Injury of nerves at lower leg level	0.588	0.412
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.588	0.412
S81 Open wound of lower leg	0.588	0.412
S80 Superficial injury of lower leg	0.588	0.412
D22.9 Melanocytic naevi, unspecified	0.587	0.413
D22.6 Melanocytic naevi of upper limb, including shoulder	0.587	0.413
D22.2 Melanocytic naevi of ear and external auricular canal	0.587	0.413
D22.1 Melanocytic naevi of eyelid, including canthus	0.587	0.413
D22.0 Melanocytic naevi of lip	0.587	0.413
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.587	0.413
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.586	0.414
L20-L30 Dermatitis and eczema	0.586	0.414
F17 Mental and behavioural disorders due to use of tobacco	0.585	0.415
N70 Salpingitis and oophoritis	0.585	0.415
D13.2 Duodenum	0.584	0.416
M06.0 Seronegative rheumatoid arthritis	0.584	0.416
M79.00 Rheumatism, unspecified (Multiple sites)	0.584	0.416
O46 Antepartum haemorrhage, not elsewhere classified	0.583	0.417
H81 Disorders of vestibular function	0.583	0.417
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.582	0.418
H94 Other disorders of ear in diseases classified elsewhere	0.582	0.418
H92 Otalgia and effusion of ear	0.582	0.418
H90 Conductive and sensorineural hearing loss	0.582	0.418
E05.8 Other thyrotoxicosis	0.581	0.419
E05.5 Thyroid crisis or storm	0.581	0.419
E05.4 Thyrotoxicosis factitia	0.581	0.419
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.581	0.419
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.581	0.419
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.581	0.419
M21.3 Wrist or foot drop (acquired)	0.581	0.419
D17.6 Benign lipomatous neoplasm of spermatic cord	0.579	0.421
I74 Arterial embolism and thrombosis	0.579	0.421
T51 Toxic effect of alcohol	0.577	0.423
H35.9 Retinal disorder, unspecified	0.577	0.423
D23.9 Skin, unspecified	0.577	0.423
D23.7 Skin of lower limb, including hip	0.577	0.423
D23.4 Skin of scalp and neck	0.577	0.423

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations