TreeWAS – Variant ID: rs11648003

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.994	0.006	0.000
E78.5 Hyperlipidaemia, unspecified	0.991	0.009	0.000
E78.2 Mixed hyperlipidaemia	0.793	0.207	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.775	0.225	0.000
E78.6 Lipoprotein deficiency	0.744	0.256	0.000
E78.3 Hyperchylomicronaemia	0.712	0.287	0.000
E78.4 Other hyperlipidaemia	0.642	0.358	0.000
E70-E90 Metabolic disorders	0.623	0.377	0.000
E88 Other metabolic disorders	0.608	0.392	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.602	0.398	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.596	0.404	0.000
J45.9 Asthma, unspecified	0.589	0.411	0.000
E89.0 Postprocedural hypothyroidism	0.587	0.413	0.000
E78.1 Pure hyperglyceridaemia	0.573	0.427	0.000
E78.8 Other disorders of lipoprotein metabolism	0.556	0.444	0.000
E73 Lactose intolerance	0.528	0.472	0.000
E84 Cystic fibrosis	0.492	0.508	0.000
E73.9 Lactose intolerance, unspecified	0.459	0.541	0.000
E89.2 Postprocedural hypoparathyroidism	0.449	0.551	0.000
E77 Disorders of glycoprotein metabolism	0.447	0.553	0.000
E76 Disorders of glycosaminoglycan metabolism	0.447	0.553	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.447	0.553	0.000
E72 Other disorders of amino-acid metabolism	0.447	0.553	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.447	0.553	0.000
E70 Disorders of aromatic amino-acid metabolism	0.447	0.553	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.447	0.553	0.000
J45 Asthma	0.438	0.562	0.000
E88.9 Metabolic disorder, unspecified	0.436	0.564	0.000
E88.8 Other specified metabolic disorders	0.436	0.564	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.436	0.564	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.427	0.573	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.427	0.573	0.000
E89.5 Postprocedural testicular hypofunction	0.427	0.573	0.000
E89.1 Postprocedural hypoinsulinaemia	0.427	0.573	0.000
E74 Other disorders of carbohydrate metabolism	0.426	0.574	0.000
E88.3 Tumour lysis syndrome	0.424	0.576	0.000
E85 Amyloidosis	0.422	0.578	0.000
E79 Disorders of purine and pyrimidine metabolism	0.410	0.590	0.000
E89.4 Postprocedural ovarian failure	0.400	0.600	0.000
E84.9 Cystic fibrosis, unspecified	0.398	0.602	0.000
E73.8 Other lactose intolerance	0.378	0.622	0.000
E73.1 Secondary lactase deficiency	0.378	0.622	0.000
E73.0 Congenital lactase deficiency	0.378	0.622	0.000
E89.3 Postprocedural hypopituitarism	0.374	0.626	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.373	0.627	0.000
E88.2 Lipomatosis, not elsewhere classified	0.362	0.638	0.000
E84.8 Cystic fibrosis with other manifestations	0.353	0.647	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.353	0.647	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.353	0.647	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.345	0.655	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.340	0.660	0.000
E85.9 Amyloidosis, unspecified	0.336	0.664	0.000
J45.0 Predominantly allergic asthma	0.326	0.674	0.000
J45.8 Mixed asthma	0.324	0.676	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.320	0.679	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.320	0.679	0.000
E70.3 Albinism	0.320	0.679	0.000
E70.2 Disorders of tyrosine metabolism	0.320	0.679	0.000
E70.1 Other hyperphenylalaninaemias	0.320	0.679	0.000
E70.0 Classical phenylketonuria	0.320	0.679	0.000
E71.3 Disorders of fatty-acid metabolism	0.320	0.679	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.320	0.679	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.320	0.679	0.000
E71.0 Maple-syrup-urine disease	0.320	0.679	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.320	0.679	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.320	0.679	0.000
E72.5 Disorders of glycine metabolism	0.320	0.679	0.000
E72.4 Disorders of ornithine metabolism	0.320	0.679	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.320	0.679	0.000
E72.2 Disorders of urea cycle metabolism	0.320	0.679	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.320	0.679	0.000
E72.0 Disorders of amino-acid transport	0.320	0.679	0.000
E75.6 Lipid storage disorder, unspecified	0.320	0.679	0.000
E75.5 Other lipid storage disorders	0.320	0.679	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.320	0.679	0.000
E75.3 Sphingolipidosis, unspecified	0.320	0.679	0.000
E75.2 Other sphingolipidosis	0.320	0.679	0.000
E75.1 Other gangliosidosis	0.320	0.679	0.000
E75.0 GM2 gangliosidosis	0.320	0.679	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.320	0.679	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.320	0.679	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.320	0.679	0.000
E76.2 Other mucopolysaccharidoses	0.320	0.679	0.000
E76.1 Mucopolysaccharidosis, type II	0.320	0.679	0.000
E76.0 Mucopolysaccharidosis, type I	0.320	0.679	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.320	0.679	0.000
E77.8 Other disorders of glycoprotein metabolism	0.320	0.679	0.000
E77.1 Defects in glycoprotein degradation	0.320	0.679	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.320	0.679	0.000
J45.1 Nonallergic asthma	0.312	0.687	0.000
J40-J47 Chronic lower respiratory diseases	0.311	0.689	0.000
J44 Other chronic obstructive pulmonary disease	0.311	0.689	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.306	0.694	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.306	0.694	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.306	0.694	0.000
E74.2 Disorders of galactose metabolism	0.306	0.694	0.000
E74.1 Disorders of fructose metabolism	0.306	0.694	0.000
E74.0 Glycogen storage disease	0.306	0.694	0.000
E85.8 Other amyloidosis	0.303	0.697	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.303	0.697	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.303	0.697	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.303	0.697	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.294	0.706	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.294	0.706	0.000
E79.1 Lesch-Nyhan syndrome	0.294	0.706	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.285	0.715	0.000
E85.3 Secondary systemic amyloidosis	0.279	0.721	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.267	0.732	0.000
E80.5 Crigler-Najjar syndrome	0.267	0.732	0.000
E80.3 Defects of catalase and peroxydase	0.267	0.732	0.000
E80.0 Hereditary erythropoietic porphyria	0.267	0.732	0.000
E80.1 Porphyria cutanea tarda	0.262	0.738	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.258	0.742	0.000
E80.4 Gilbert's syndrome	0.255	0.744	0.000
E85.4 Organ-limited amyloidosis	0.255	0.745	0.000
E80.6 Other disorders of bilirubin metabolism	0.252	0.747	0.000
E80.2 Other porphyria	0.240	0.760	0.000
J41 Simple and mucopurulent chronic bronchitis	0.239	0.761	0.000
J43 Emphysema	0.214	0.786	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.213	0.787	0.000
J46 Status asthmaticus	0.204	0.796	0.000
J41.0 Simple chronic bronchitis	0.187	0.812	0.000
J42 Unspecified chronic bronchitis	0.177	0.822	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.172	0.828	0.000
J41.1 Mucopurulent chronic bronchitis	0.172	0.828	0.000
J43.9 Emphysema, unspecified	0.155	0.845	0.000
J43.1 Panlobular emphysema	0.154	0.846	0.000
J43.0 MacLeod's syndrome	0.154	0.846	0.000
J43.8 Other emphysema	0.150	0.849	0.000
J43.2 Centrilobular emphysema	0.146	0.854	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.142	0.858	0.000
J47 Bronchiectasis	0.131	0.869	0.000
J40 Bronchitis, not specified as acute or chronic	0.123	0.877	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.117	0.883	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.091	0.909	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.083	0.916	0.000
E83 Disorders of mineral metabolism	0.074	0.926	0.000
Z82.2 Family history of deafness and hearing loss	0.073	0.927	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.073	0.927	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.070	0.930	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.065	0.934	0.000
Z82.3 Family history of stroke	0.059	0.941	0.000
Z82.1 Family history of blindness and visual loss	0.055	0.945	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.053	0.947	0.000
E83.8 Other disorders of mineral metabolism	0.053	0.947	0.000
E83.2 Disorders of zinc metabolism	0.053	0.947	0.000
E83.0 Disorders of copper metabolism	0.053	0.947	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.051	0.949	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.046	0.954	0.000
E83.3 Disorders of phosphorus metabolism	0.043	0.957	0.000
E83.4 Disorders of magnesium metabolism	0.037	0.963	0.000
M16.0 Primary coxarthrosis, bilateral	0.035	0.965	0.000
M16.9 Coxarthrosis, unspecified	0.033	0.967	0.000
E86 Volume depletion	0.032	0.968	0.000
M16 Coxarthrosis [arthrosis of hip]	0.031	0.969	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.031	0.969	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.970	0.030
E20-E35 Disorders of other endocrine glands	0.027	0.973	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.026	0.974	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.026	0.974	0.000
E28 Ovarian dysfunction	0.025	0.975	0.000
E28.2 Polycystic ovarian syndrome	0.025	0.975	0.000
E20 Hypoparathyroidism	0.024	0.976	0.000
E26 Hyperaldosteronism	0.023	0.977	0.000
E34 Other endocrine disorders	0.023	0.977	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.023	0.977	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.022	0.977	0.000
M16.5 Other posttraumatic coxarthrosis	0.023	0.977	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.022	0.977	0.000
E16 Other disorders of pancreatic internal secretion	0.022	0.977	0.000
E20.9 Hypoparathyroidism, unspecified	0.022	0.978	0.000
M16.1 Other primary coxarthrosis	0.022	0.978	0.000
M16.7 Other secondary coxarthrosis	0.021	0.979	0.000
E26.0 Primary hyperaldosteronism	0.021	0.979	0.000
E21.0 Primary hyperparathyroidism	0.021	0.979	0.000
E34.8 Other specified endocrine disorders	0.020	0.980	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.020	0.980	0.000
E83.5 Disorders of calcium metabolism	0.020	0.980	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.019	0.981	0.000
E32 Diseases of thymus	0.019	0.981	0.000
E31 Polyglandular dysfunction	0.019	0.981	0.000
E30 Disorders of puberty, not elsewhere classified	0.019	0.981	0.000
E25 Adrenogenital disorders	0.019	0.981	0.000
E16.1 Other hypoglycaemia	0.019	0.981	0.000
E15 Nondiabetic hypoglycaemic coma	0.019	0.981	0.000
E40-E46 Malnutrition	0.019	0.981	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.019	0.981	0.000
E28.9 Ovarian dysfunction, unspecified	0.018	0.982	0.000
E28.8 Other ovarian dysfunction	0.018	0.982	0.000
E28.1 Androgen excess	0.018	0.982	0.000
E28.0 Oestrogen excess	0.018	0.982	0.000
E34.9 Endocrine disorder, unspecified	0.018	0.982	0.000
E28.3 Primary ovarian failure	0.018	0.982	0.000
E16.2 Hypoglycaemia, unspecified	0.017	0.983	0.000
E20.8 Other hypoparathyroidism	0.017	0.983	0.000
E20.1 Pseudohypoparathyroidism	0.017	0.983	0.000
E20.0 Idiopathic hypoparathyroidism	0.017	0.983	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.017	0.983	0.000
E29 Testicular dysfunction	0.017	0.983	0.000
E26.9 Hyperaldosteronism, unspecified	0.017	0.983	0.000
E26.8 Other hyperaldosteronism	0.017	0.983	0.000
E26.1 Secondary hyperaldosteronism	0.017	0.983	0.000
E34.5 Androgen resistance syndrome	0.017	0.983	0.000
E34.4 Constitutional tall stature	0.017	0.983	0.000
E34.3 Short stature, not elsewhere classified	0.017	0.983	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.017	0.983	0.000
E34.1 Other hypersecretion of intestinal hormones	0.017	0.983	0.000
E21.4 Other specified disorders of parathyroid gland	0.016	0.983	0.000
E21.2 Other hyperparathyroidism	0.016	0.983	0.000
E83.1 Disorders of iron metabolism	0.016	0.984	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.016	0.984	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.016	0.984	0.000
E16.4 Abnormal secretion of gastrin	0.016	0.984	0.000
E16.3 Increased secretion of glucagon	0.016	0.984	0.000
E34.0 Carcinoid syndrome	0.016	0.984	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.016	0.984	0.000
K83.1 Obstruction of bile duct	0.000	0.985	0.015
E24 Cushing's syndrome	0.015	0.985	0.000
E87.3 Alkalosis	0.015	0.985	0.000
E87.7 Fluid overload	0.015	0.985	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.015	0.985	0.000
E87.4 Mixed disorder of acid-base balance	0.014	0.985	0.000
M16.3 Other dysplastic coxarthrosis	0.014	0.986	0.000
E25.9 Adrenogenital disorder, unspecified	0.014	0.986	0.000
E25.8 Other adrenogenital disorders	0.014	0.986	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.014	0.986	0.000
E30.9 Disorder of puberty, unspecified	0.014	0.986	0.000
E30.8 Other disorders of puberty	0.014	0.986	0.000
E30.1 Precocious puberty	0.014	0.986	0.000
E30.0 Delayed puberty	0.014	0.986	0.000
E31.9 Polyglandular dysfunction, unspecified	0.014	0.986	0.000
E31.8 Other polyglandular dysfunction	0.014	0.986	0.000
E31.1 Polyglandular hyperfunction	0.014	0.986	0.000
E31.0 Autoimmune polyglandular failure	0.014	0.986	0.000
E32.9 Disease of thymus, unspecified	0.014	0.986	0.000
E32.8 Other diseases of thymus	0.014	0.986	0.000
E32.1 Abscess of thymus	0.014	0.986	0.000
E32.0 Persistent hyperplasia of thymus	0.014	0.986	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.014	0.986	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.014	0.986	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.014	0.986	0.000
E22 Hyperfunction of pituitary gland	0.013	0.986	0.001
E87.5 Hyperkalaemia	0.014	0.986	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.014	0.986	0.000
E45 Retarded development following protein-energy malnutrition	0.014	0.986	0.000
E43 Unspecified severe protein-energy malnutrition	0.014	0.986	0.000
E42 Marasmic kwashiorkor	0.014	0.986	0.000
E41 Nutritional marasmus	0.014	0.986	0.000
E40 Kwashiorkor	0.014	0.986	0.000
E65-E68 Obesity and other hyperalimentation	0.013	0.987	0.000
E21.3 Hyperparathyroidism, unspecified	0.013	0.987	0.000
E50-E64 Other nutritional deficiencies	0.013	0.987	0.000
E29.9 Testicular dysfunction, unspecified	0.012	0.988	0.000
E29.8 Other testicular dysfunction	0.012	0.988	0.000
E29.0 Testicular hyperfunction	0.012	0.988	0.000
E22.1 Hyperprolactinaemia	0.012	0.988	0.000
E24.2 Drug-induced Cushing's syndrome	0.011	0.989	0.000
E24.8 Other Cushing's syndrome	0.011	0.989	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.011	0.989	0.000
E24.3 Ectopic ACTH syndrome	0.011	0.989	0.000
E24.1 Nelson's syndrome	0.011	0.989	0.000
E46 Unspecified protein-energy malnutrition	0.010	0.990	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.010	0.990	0.001
E22.8 Other hyperfunction of pituitary gland	0.010	0.990	0.001
E24.0 Pituitary-dependent Cushing's disease	0.010	0.990	0.000
E44.1 Mild protein-energy malnutrition	0.010	0.990	0.000
E44.0 Moderate protein-energy malnutrition	0.010	0.990	0.000
E29.1 Testicular hypofunction	0.010	0.990	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.010	0.990	0.000
E67 Other hyperalimentation	0.009	0.990	0.000
E68 Sequelae of hyperalimentation	0.009	0.990	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.009	0.991	0.000
E63 Other nutritional deficiencies	0.009	0.991	0.000
E56 Other vitamin deficiencies	0.009	0.991	0.000
E51 Thiamine deficiency	0.009	0.991	0.000
E50 Vitamin A deficiency	0.009	0.991	0.000
E60 Dietary zinc deficiency	0.009	0.991	0.000
E59 Dietary selenium deficiency	0.009	0.991	0.000
E54 Ascorbic acid deficiency	0.009	0.991	0.000
E52 Niacin deficiency [pellagra]	0.009	0.991	0.000
E58 Dietary calcium deficiency	0.009	0.991	0.000
I25.1 Atherosclerotic heart disease	0.009	0.991	0.000
E53 Deficiency of other B group vitamins	0.008	0.992	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.008	0.992	0.000
E65 Localised adiposity	0.008	0.992	0.000
E24.9 Cushing's syndrome, unspecified	0.008	0.992	0.000
K83.0 Cholangitis	0.000	0.992	0.008
K83 Other diseases of biliary tract	0.000	0.992	0.008
Z99.8 Dependence on other enabling machines and devices	0.008	0.992	0.000
Z99.3 Dependence on wheelchair	0.008	0.992	0.000
E55 Vitamin D deficiency	0.007	0.992	0.000
E87.0 Hyperosmolality and hypernatraemia	0.007	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.993	0.001
E67.8 Other specified hyperalimentation	0.007	0.993	0.000
E67.3 Hypervitaminosis D	0.007	0.993	0.000
E67.2 Megavitamin-B6 syndrome	0.007	0.993	0.000
E67.1 Hypercarotenaemia	0.007	0.993	0.000
E67.0 Hypervitaminosis A	0.007	0.993	0.000
E10-E14 Diabetes mellitus	0.007	0.993	0.000
E50.9 Vitamin A deficiency, unspecified	0.007	0.993	0.000
E50.8 Other manifestations of vitamin A deficiency	0.007	0.993	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.007	0.993	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.007	0.993	0.000
E50.5 Vitamin A deficiency with night blindness	0.007	0.993	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.007	0.993	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.007	0.993	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.007	0.993	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.007	0.993	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.007	0.993	0.000
E51.9 Thiamine deficiency, unspecified	0.007	0.993	0.000
E51.8 Other manifestations of thiamine deficiency	0.007	0.993	0.000
E51.2 Wernicke's encephalopathy	0.007	0.993	0.000
E51.1 Beriberi	0.007	0.993	0.000
E56.9 Vitamin deficiency, unspecified	0.007	0.993	0.000
E56.8 Deficiency of other vitamins	0.007	0.993	0.000
E56.1 Deficiency of vitamin K	0.007	0.993	0.000
E56.0 Deficiency of vitamin E	0.007	0.993	0.000
E63.9 Nutritional deficiency, unspecified	0.007	0.993	0.000
E63.8 Other specified nutritional deficiencies	0.007	0.993	0.000
E63.1 Imbalance of constituents of food intake	0.007	0.993	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.007	0.993	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.007	0.993	0.000
E64.8 Sequelae of other nutritional deficiencies	0.007	0.993	0.000
E64.3 Sequelae of rickets	0.007	0.993	0.000
E64.2 Sequelae of vitamin C deficiency	0.007	0.993	0.000
E64.1 Sequelae of vitamin A deficiency	0.007	0.993	0.000
E64.0 Sequelae of protein-energy malnutrition	0.007	0.993	0.000
I25 Chronic ischaemic heart disease	0.007	0.993	0.000
Q66.8 Other congenital deformities of feet	0.007	0.993	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.006	0.994	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
E61 Deficiency of other nutrient elements	0.006	0.994	0.001
E53.9 Vitamin B deficiency, unspecified	0.006	0.994	0.000
E53.1 Pyridoxine deficiency	0.006	0.994	0.000
E53.0 Riboflavin deficiency	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.994	0.006
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.006	0.994	0.000
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
E13 Other specified diabetes mellitus	0.006	0.994	0.000
K83.5 Biliary cyst	0.000	0.994	0.006
K83.4 Spasm of sphincter of Oddi	0.000	0.994	0.006
K83.2 Perforation of bile duct	0.000	0.994	0.006
K83.9 Disease of biliary tract, unspecified	0.000	0.994	0.006
I25.5 Ischaemic cardiomyopathy	0.006	0.994	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.006	0.994	0.000
E87.2 Acidosis	0.006	0.994	0.000
E55.0 Rickets, active	0.006	0.994	0.000
K83.3 Fistula of bile duct	0.000	0.994	0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.001
E23.1 Drug-induced hypopituitarism	0.005	0.995	0.001
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.995	0.000
E12 Malnutrition-related diabetes mellitus	0.005	0.995	0.000
C50.4 Upper-outer quadrant of breast	0.005	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.004	0.995	0.001
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.001
Q65 Congenital deformities of hip	0.005	0.995	0.000
Q66.0 Talipes equinovarus	0.005	0.995	0.000
I25.6 Silent myocardial ischaemia	0.005	0.995	0.000
E13.9 Without complications	0.005	0.995	0.000
I25.3 Aneurysm of heart	0.005	0.995	0.000
E00-E07 Disorders of thyroid gland	0.005	0.995	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.004	0.995	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.995	0.001
Z99.0 Dependence on aspirator	0.005	0.995	0.000
J30.0 Vasomotor rhinitis	0.000	0.995	0.005
G55.3 Nerve root and plexus compressions in other dorsopathies	0.005	0.995	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.005	0.995	0.000
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.005	0.995	0.000
E61.9 Deficiency of nutrient element, unspecified	0.004	0.995	0.001
E61.8 Deficiency of other specified nutrient elements	0.004	0.995	0.001
E61.7 Deficiency of multiple nutrient elements	0.004	0.995	0.001
E61.6 Vanadium deficiency	0.004	0.995	0.001
E61.5 Molybdenum deficiency	0.004	0.995	0.001
E61.4 Chromium deficiency	0.004	0.995	0.001
E61.3 Manganese deficiency	0.004	0.995	0.001
E61.0 Copper deficiency	0.004	0.995	0.001
Z04.3 Examination and observation following other accident	0.000	0.995	0.005
Q66.7 Pes cavus	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.004	0.995	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
E61.2 Magnesium deficiency	0.004	0.995	0.000
Q65.8 Other congenital deformities of hip	0.005	0.995	0.000
Q67.5 Congenital deformity of spine	0.005	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.995	0.000
Q76.7 Congenital malformation of sternum	0.004	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.995	0.000
Q76.5 Cervical rib	0.004	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.995	0.000
E14 Unspecified diabetes mellitus	0.005	0.995	0.000
E13.8 With unspecified complications	0.004	0.995	0.000
E13.7 With multiple complications	0.004	0.995	0.000
E13.6 With other specified complications	0.004	0.995	0.000
E13.5 With peripheral circulatory complications	0.004	0.995	0.000
E13.4 With neurological complications	0.004	0.995	0.000
E13.3 With ophthalmic complications	0.004	0.995	0.000
E13.2 With renal complications	0.004	0.995	0.000
E13.1 With ketoacidosis	0.004	0.995	0.000
E13.0 With coma	0.004	0.995	0.000
Q78 Other osteochondrodysplasias	0.004	0.995	0.000
E14.9 Without complications	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.995	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.995	0.005
E87.6 Hypokalaemia	0.005	0.995	0.000
Q76.0 Spina bifida occulta	0.004	0.995	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.004	0.995	0.000
Z99.4 Dependence on artificial heart	0.004	0.995	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
I25.2 Old myocardial infarction	0.004	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
C50.8 Overlapping lesion of breast	0.004	0.996	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.996	0.004
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
E12.9 Without complications	0.004	0.996	0.000
E12.8 With unspecified complications	0.004	0.996	0.000
E12.7 With multiple complications	0.004	0.996	0.000
E12.6 With other specified complications	0.004	0.996	0.000
E12.5 With peripheral circulatory complications	0.004	0.996	0.000
E12.4 With neurological complications	0.004	0.996	0.000
E12.3 With ophthalmic complications	0.004	0.996	0.000
E12.2 With renal complications	0.004	0.996	0.000
E12.1 With ketoacidosis	0.004	0.996	0.000
E12.0 With coma	0.004	0.996	0.000
I25.4 Coronary artery aneurysm	0.004	0.996	0.000
J30.3 Other allergic rhinitis	0.000	0.996	0.004
Q65.9 Congenital deformity of hip, unspecified	0.004	0.996	0.000
Q65.6 Unstable hip	0.004	0.996	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.004	0.996	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.004	0.996	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.004	0.996	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.004	0.996	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.004	0.996	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.004	0.996	0.000
Z71.3 Dietary counselling and surveillance	0.004	0.996	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.004	0.996	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.004	0.996	0.000
Q79.5 Other congenital malformations of abdominal wall	0.004	0.996	0.000
Q79.4 Prune belly syndrome	0.004	0.996	0.000
Q79.3 Gastroschisis	0.004	0.996	0.000
Q79.2 Exomphalos	0.004	0.996	0.000
Q79.1 Other congenital malformations of diaphragm	0.004	0.996	0.000
Q79.0 Congenital diaphragmatic hernia	0.004	0.996	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E00 Congenital iodine-deficiency syndrome	0.004	0.996	0.000
Z71.9 Counselling, unspecified	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.004	0.996	0.000
E66 Obesity	0.004	0.996	0.000
E06 Thyroiditis	0.004	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.996	0.000
Q68.3 Congenital bowing of femur	0.003	0.996	0.000
Q68.2 Congenital deformity of knee	0.003	0.996	0.000
Q68.1 Congenital deformity of hand	0.003	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.996	0.000
Q69.9 Polydactyly, unspecified	0.003	0.996	0.000
Q69.2 Accessory toe(s)	0.003	0.996	0.000
Q69.1 Accessory thumb(s)	0.003	0.996	0.000
Q69.0 Accessory finger(s)	0.003	0.996	0.000
Q70.9 Syndactyly, unspecified	0.003	0.996	0.000
Q70.4 Polysyndactyly	0.003	0.996	0.000
Q70.3 Webbed toes	0.003	0.996	0.000
Q70.2 Fused toes	0.003	0.996	0.000
Q70.1 Webbed fingers	0.003	0.996	0.000
Q70.0 Fused fingers	0.003	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.996	0.000
Q71.6 Lobster-claw hand	0.003	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations