TreeWAS – Variant ID: rs1165165

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.999	0.001	0.000
E10 Insulin-dependent diabetes mellitus	0.999	0.001	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.998	0.002	0.000
E10.9 Without complications	0.998	0.002	0.000
E05.9 Thyrotoxicosis, unspecified	0.991	0.009	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.973	0.027	0.000
E20-E35 Disorders of other endocrine glands	0.964	0.036	0.000
E16 Other disorders of pancreatic internal secretion	0.953	0.047	0.000
E16.2 Hypoglycaemia, unspecified	0.944	0.056	0.000
E27 Other disorders of adrenal gland	0.924	0.076	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.880	0.120	0.000
E14 Unspecified diabetes mellitus	0.879	0.121	0.000
E27.1 Primary adrenocortical insufficiency	0.873	0.127	0.000
E10.5 With peripheral circulatory complications	0.853	0.147	0.000
E23 Hypofunction and other disorders of pituitary gland	0.847	0.153	0.000
E22 Hyperfunction of pituitary gland	0.838	0.162	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.834	0.165	0.000
D64.9 Anaemia, unspecified	0.823	0.177	0.000
E50-E64 Other nutritional deficiencies	0.816	0.184	0.000
K90 Intestinal malabsorption	0.815	0.185	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.809	0.191	0.000
E10.2 With renal complications	0.807	0.193	0.000
E13 Other specified diabetes mellitus	0.805	0.195	0.000
E10.8 With unspecified complications	0.798	0.202	0.000
E10.7 With multiple complications	0.781	0.219	0.000
E14.3 With ophthalmic complications	0.780	0.220	0.000
E05.8 Other thyrotoxicosis	0.774	0.226	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.769	0.231	0.000
E27.2 Addisonian crisis	0.766	0.234	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.754	0.246	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.742	0.258	0.000
E14.5 With peripheral circulatory complications	0.737	0.263	0.000
E10.3 With ophthalmic complications	0.736	0.264	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.731	0.269	0.000
E23.7 Disorder of pituitary gland, unspecified	0.731	0.269	0.000
E10.6 With other specified complications	0.730	0.270	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.716	0.283	0.000
E05.5 Thyroid crisis or storm	0.715	0.284	0.000
E05.4 Thyrotoxicosis factitia	0.715	0.284	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.715	0.284	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.715	0.284	0.000
E20 Hypoparathyroidism	0.715	0.285	0.000
E14.6 With other specified complications	0.708	0.292	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.705	0.295	0.000
E21.3 Hyperparathyroidism, unspecified	0.705	0.295	0.000
E15 Nondiabetic hypoglycaemic coma	0.697	0.303	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.691	0.309	0.000
E32 Diseases of thymus	0.691	0.309	0.000
E31 Polyglandular dysfunction	0.691	0.309	0.000
E30 Disorders of puberty, not elsewhere classified	0.691	0.309	0.000
E25 Adrenogenital disorders	0.691	0.309	0.000
E10.0 With coma	0.690	0.310	0.000
M10 Gout	0.689	0.311	0.000
E07 Other disorders of thyroid	0.689	0.311	0.000
M10.9 Gout, unspecified	0.687	0.313	0.000
M05-M14 Inflammatory polyarthropathies	0.686	0.314	0.000
M35.0 Sicca syndrome [Sjogren]	0.686	0.314	0.000
E14.1 With ketoacidosis	0.685	0.315	0.000
E23.6 Other disorders of pituitary gland	0.685	0.315	0.000
M20-M25 Other joint disorders	0.684	0.316	0.000
M15-M19 Arthrosis	0.684	0.316	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.683	0.317	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.683	0.317	0.000
E16.4 Abnormal secretion of gastrin	0.683	0.317	0.000
E16.3 Increased secretion of glucagon	0.683	0.317	0.000
M35 Other systemic involvement of connective tissue	0.682	0.318	0.000
E10.4 With neurological complications	0.682	0.318	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.682	0.318	0.000
M17 Gonarthrosis [arthrosis of knee]	0.679	0.321	0.000
E22.1 Hyperprolactinaemia	0.679	0.321	0.000
E16.1 Other hypoglycaemia	0.671	0.329	0.000
E61 Deficiency of other nutrient elements	0.669	0.331	0.000
M10.99 Gout, unspecified (Site unspecified)	0.667	0.333	0.000
M23 Internal derangement of knee	0.666	0.334	0.000
E27.5 Adrenomedullary hyperfunction	0.662	0.338	0.000
E27.0 Other adrenocortical overactivity	0.662	0.338	0.000
K90.9 Intestinal malabsorption, unspecified	0.658	0.342	0.000
E23.2 Diabetes insipidus	0.658	0.342	0.000
M17.9 Gonarthrosis, unspecified	0.656	0.344	0.000
E34 Other endocrine disorders	0.647	0.353	0.000
M18 Arthrosis of first carpometacarpal joint	0.644	0.356	0.000
D64 Other anaemias	0.639	0.361	0.000
E10.1 With ketoacidosis	0.637	0.363	0.000
M11 Other crystal arthropathies	0.636	0.364	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.632	0.368	0.000
E13.3 With ophthalmic complications	0.631	0.369	0.000
E14.7 With multiple complications	0.630	0.370	0.000
E14.2 Withrenal complications	0.630	0.370	0.000
E14.0 With coma	0.630	0.370	0.000
M10.0 Idiopathic gout	0.629	0.371	0.000
M34 Systemic sclerosis	0.628	0.372	0.000
E13.9 Without complications	0.622	0.378	0.000
E21.4 Other specified disorders of parathyroid gland	0.621	0.379	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.619	0.381	0.000
E27.9 Disorder of adrenal gland, unspecified	0.617	0.383	0.000
M10.96 Gout, unspecified (Lower leg)	0.615	0.385	0.000
M15 Polyarthrosis	0.615	0.385	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.611	0.389	0.000
M00-M03 Infectious arthropathies	0.611	0.389	0.000
M10.90 Gout, unspecified (Multiple sites)	0.610	0.390	0.000
E07.8 Other specified disorders of thyroid	0.609	0.391	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.607	0.393	0.000
E23.1 Drug-induced hypopituitarism	0.607	0.393	0.000
M17.0 Primary gonarthrosis, bilateral	0.605	0.395	0.000
M23.4 Loose body in knee	0.603	0.397	0.000
M86-M90 Other osteopathies	0.602	0.398	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.601	0.399	0.000
E22.8 Other hyperfunction of pituitary gland	0.601	0.399	0.000
E51 Thiamine deficiency	0.600	0.400	0.000
M11.2 Other chondrocalcinosis	0.598	0.401	0.000
E14.8 With unspecified complications	0.598	0.402	0.000
E24 Cushing's syndrome	0.596	0.404	0.000
E55 Vitamin D deficiency	0.595	0.405	0.000
E58 Dietary calcium deficiency	0.592	0.408	0.000
K90.8 Other intestinal malabsorption	0.586	0.414	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.585	0.414	0.000
E63 Other nutritional deficiencies	0.585	0.414	0.000
E56 Other vitamin deficiencies	0.585	0.414	0.000
E50 Vitamin A deficiency	0.585	0.414	0.000
E60 Dietary zinc deficiency	0.585	0.414	0.000
E59 Dietary selenium deficiency	0.585	0.414	0.000
E54 Ascorbic acid deficiency	0.585	0.414	0.000
E52 Niacin deficiency [pellagra]	0.585	0.414	0.000
K90.3 Pancreatic steatorrhoea	0.584	0.416	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.584	0.416	0.000
K90.1 Tropical sprue	0.584	0.416	0.000
M23.8 Other internal derangements of knee	0.584	0.416	0.000
E53 Deficiency of other B group vitamins	0.581	0.419	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.580	0.420	0.000
E21.2 Other hyperparathyroidism	0.580	0.420	0.000
E13.8 With unspecified complications	0.577	0.423	0.000
E13.7 With multiple complications	0.577	0.423	0.000
E13.6 With other specified complications	0.577	0.423	0.000
E13.5 With peripheral circulatory complications	0.577	0.423	0.000
E13.4 With neurological complications	0.577	0.423	0.000
E13.2 With renal complications	0.577	0.423	0.000
E13.1 With ketoacidosis	0.577	0.423	0.000
E13.0 With coma	0.577	0.423	0.000
E61.1 Iron deficiency	0.576	0.424	0.000
E21.0 Primary hyperparathyroidism	0.576	0.424	0.000
E26 Hyperaldosteronism	0.575	0.424	0.000
M23.3 Other meniscus derangements	0.574	0.426	0.000
M23.49 Loose body in knee-Unspec lig/men	0.572	0.428	0.000
E27.8 Other specified disorders of adrenal gland	0.569	0.431	0.000
M07 Psoriatic and enteropathic arthropathies	0.569	0.431	0.000
M00 Pyogenic arthritis	0.567	0.433	0.000
E03.8 Other specified hypothyroidism	0.566	0.434	0.000
M35.7 Hypermobility syndrome	0.566	0.434	0.000
M17.1 Other primary gonarthrosis	0.566	0.434	0.000
M87 Osteonecrosis	0.565	0.435	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.562	0.438	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.562	0.438	0.000
E14.4 With neurological complications	0.558	0.442	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.553	0.447	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.551	0.449	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.547	0.453	0.000
M60-M63 Disorders of muscles	0.545	0.455	0.000
E28 Ovarian dysfunction	0.544	0.455	0.000
M12 Other specific arthropathies	0.537	0.462	0.000
E20.9 Hypoparathyroidism, unspecified	0.536	0.464	0.000
M33 Dermatopolymyositis	0.534	0.466	0.000
M00.9 Pyogenic arthritis, unspecified	0.532	0.468	0.000
M17.3 Other posttraumatic gonarthrosis	0.532	0.468	0.000
M23.0 Cystic meniscus	0.531	0.469	0.000
M10.94 Gout, unspecified (Hand)	0.528	0.472	0.000
M17.5 Other secondary gonarthrosis	0.527	0.473	0.000
M22 Disorders of patella	0.525	0.475	0.000
E40-E46 Malnutrition	0.524	0.476	0.000
E23.0 Hypopituitarism	0.523	0.477	0.000
E34.9 Endocrine disorder, unspecified	0.523	0.477	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.520	0.480	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.482	0.518
M32 Systemic lupus erythematosus	0.517	0.483	0.000
M34.1 CR(E)ST syndrome	0.516	0.484	0.000
M34.9 Systemic sclerosis, unspecified	0.515	0.485	0.000
K51 Ulcerative colitis	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E20.8 Other hypoparathyroidism	0.512	0.487	0.000
E20.1 Pseudohypoparathyroidism	0.512	0.487	0.000
E20.0 Idiopathic hypoparathyroidism	0.512	0.487	0.000
E06 Thyroiditis	0.510	0.489	0.000
M87.9 Osteonecrosis, unspecified	0.510	0.490	0.000
D64.3 Other sideroblastic anaemias	0.508	0.492	0.000
M14 Arthropathies in other diseases classified elsewhere	0.507	0.493	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.504	0.496	0.000
M86 Osteomyelitis	0.503	0.497	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.500	0.500	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.499	0.501	0.000
M34.0 Progressive systemic sclerosis	0.498	0.502	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.498	0.502	0.000
M15.0 Primary generalised (osteo)arthrosis	0.498	0.502	0.000
E25.9 Adrenogenital disorder, unspecified	0.495	0.504	0.000
E25.8 Other adrenogenital disorders	0.495	0.504	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.495	0.504	0.000
E30.9 Disorder of puberty, unspecified	0.495	0.504	0.000
E30.8 Other disorders of puberty	0.495	0.504	0.000
E30.1 Precocious puberty	0.495	0.504	0.000
E30.0 Delayed puberty	0.495	0.504	0.000
E31.9 Polyglandular dysfunction, unspecified	0.495	0.504	0.000
E31.8 Other polyglandular dysfunction	0.495	0.504	0.000
E31.1 Polyglandular hyperfunction	0.495	0.504	0.000
E31.0 Autoimmune polyglandular failure	0.495	0.504	0.000
E32.9 Disease of thymus, unspecified	0.495	0.504	0.000
E32.8 Other diseases of thymus	0.495	0.504	0.000
E32.1 Abscess of thymus	0.495	0.504	0.000
E32.0 Persistent hyperplasia of thymus	0.495	0.504	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.495	0.504	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.495	0.504	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.495	0.504	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.505	0.495
M10.4 Other secondary gout	0.494	0.506	0.000
M10.3 Gout due to impairment of renal function	0.494	0.506	0.000
M10.2 Drug-induced gout	0.494	0.506	0.000
M10.1 Lead-induced gout	0.494	0.506	0.000
E07.1 Dyshormogenetic goitre	0.494	0.506	0.000
E07.0 Hypersecretion of calcitonin	0.494	0.506	0.000
M10.98 Gout, unspecified (Other)	0.493	0.507	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.493	0.507	0.000
M10.91 Gout, unspecified (Shoulder region)	0.493	0.507	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.492	0.508	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.492	0.508	0.000
M08 Juvenile arthritis	0.492	0.508	0.000
M34.8 Other forms of systemic sclerosis	0.490	0.510	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.490	0.510	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.489	0.511	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.489	0.511	0.000
M35.5 Multifocal fibrosclerosis	0.489	0.511	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.489	0.511	0.000
M10.93 Gout, unspecified (Forearm)	0.486	0.514	0.000
M15.1 Heberden's nodes (with arthropathy)	0.486	0.514	0.000
M07.3 Other psoriatic arthropathies	0.485	0.515	0.000
M35.3 Polymyalgia rheumatica	0.484	0.516	0.000
M31 Other necrotising vasculopathies	0.481	0.519	0.000
E61.9 Deficiency of nutrient element, unspecified	0.480	0.520	0.000
E61.8 Deficiency of other specified nutrient elements	0.480	0.520	0.000
E61.7 Deficiency of multiple nutrient elements	0.480	0.520	0.000
E61.6 Vanadium deficiency	0.480	0.520	0.000
E61.5 Molybdenum deficiency	0.480	0.520	0.000
E61.4 Chromium deficiency	0.480	0.520	0.000
E61.3 Manganese deficiency	0.480	0.520	0.000
E61.0 Copper deficiency	0.480	0.520	0.000
K51.8 Other ulcerative colitis	0.000	0.522	0.478
M15.8 Other polyarthrosis	0.476	0.523	0.000
M10.00 Idiopathic gout (Multiple sites)	0.475	0.525	0.000
D64.8 Other specified anaemias	0.475	0.525	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.474	0.526	0.000
M19 Other arthrosis	0.473	0.527	0.000
M15.9 Polyarthrosis, unspecified	0.469	0.531	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.466	0.533	0.000
M11.9 Crystal arthropathy, unspecified	0.466	0.534	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.466	0.534	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.465	0.534	0.000
M87.8 Other osteonecrosis	0.464	0.536	0.000
E34.5 Androgen resistance syndrome	0.464	0.536	0.000
E34.4 Constitutional tall stature	0.464	0.536	0.000
E34.3 Short stature, not elsewhere classified	0.464	0.536	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.464	0.536	0.000
E34.1 Other hypersecretion of intestinal hormones	0.464	0.536	0.000
E24.2 Drug-induced Cushing's syndrome	0.464	0.536	0.000
E65-E68 Obesity and other hyperalimentation	0.463	0.537	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.462	0.538	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.462	0.538	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.462	0.538	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.462	0.538	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.461	0.538	0.000
M22.3 Other derangements of patella	0.461	0.539	0.000
E70-E90 Metabolic disorders	0.459	0.541	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.458	0.542	0.000
D64.4 Congenital dyserythropoietic anaemia	0.458	0.542	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.458	0.542	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.458	0.542	0.000
D64.0 Hereditary sideroblastic anaemia	0.458	0.542	0.000
E29 Testicular dysfunction	0.456	0.543	0.001
M62 Other disorders of muscle	0.457	0.543	0.000
M10.92 Gout, unspecified (Upper arm)	0.456	0.543	0.000
M11.1 Familial chondrocalcinosis	0.456	0.544	0.000
M11.0 Hydroxyapatite deposition disease	0.456	0.544	0.000
M23.46 Loose body in knee-O/unsp lat men	0.455	0.545	0.000
M11.8 Other specified crystal arthropathies	0.453	0.546	0.000
E61.2 Magnesium deficiency	0.453	0.547	0.000
M35.2 Behcet's disease	0.453	0.547	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.549	0.451
M10.08 Idiopathic gout (Other)	0.451	0.549	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.451	0.549	0.000
M10.04 Idiopathic gout (Hand)	0.451	0.549	0.000
M10.03 Idiopathic gout (Forearm)	0.451	0.549	0.000
M10.02 Idiopathic gout (Upper arm)	0.451	0.549	0.000
M10.01 Idiopathic gout (Shoulder region)	0.451	0.549	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.450	0.549	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.450	0.550	0.000
E53.9 Vitamin B deficiency, unspecified	0.449	0.551	0.000
M10.06 Idiopathic gout (Lower leg)	0.448	0.551	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.448	0.552	0.000
M10.09 Idiopathic gout (Site unspecified)	0.446	0.553	0.000
M87.1 Osteonecrosis due to drugs	0.445	0.555	0.000
E51.2 Wernicke's encephalopathy	0.444	0.556	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.441	0.559	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.441	0.559	0.000
M35.8 Other specified systemic involvement of connective tissue	0.441	0.559	0.000
M15.4 Erosive (osteo)arthrosis	0.441	0.559	0.000
M15.3 Secondary multiple arthrosis	0.441	0.559	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.440	0.560	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.438	0.562	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.438	0.562	0.000
D60-D64 Aplastic and other anaemias	0.437	0.563	0.000
M21 Other acquired deformities of limbs	0.436	0.564	0.000
E55.9 Vitamin D deficiency, unspecified	0.436	0.564	0.000
E34.0 Carcinoid syndrome	0.435	0.565	0.000
M19.0 Primary arthrosis of other joints	0.434	0.566	0.000
M23.47 Loose body in knee-Capsular lig	0.433	0.567	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.433	0.567	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.433	0.567	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.433	0.567	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.433	0.567	0.000
M23.40 Loose body in knee-Mult sites	0.433	0.567	0.000
M33.1 Other dermatomyositis	0.431	0.569	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.430	0.569	0.000
E51.9 Thiamine deficiency, unspecified	0.430	0.570	0.000
E51.8 Other manifestations of thiamine deficiency	0.430	0.570	0.000
E51.1 Beriberi	0.430	0.570	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.429	0.571	0.000
M11.28 Other chondrocalcinosis (Other)	0.429	0.571	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.429	0.571	0.000
M11.24 Other chondrocalcinosis (Hand)	0.429	0.571	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.429	0.571	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.429	0.571	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.429	0.571	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.429	0.571	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.429	0.571	0.000
E24.8 Other Cushing's syndrome	0.427	0.572	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.427	0.572	0.000
E24.3 Ectopic ACTH syndrome	0.427	0.572	0.000
E24.1 Nelson's syndrome	0.427	0.572	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.427	0.573	0.000
E55.0 Rickets, active	0.427	0.573	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.424	0.576	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.422	0.578	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.422	0.578	0.000
M23.5 Chronic instability of knee	0.421	0.579	0.000
E50.9 Vitamin A deficiency, unspecified	0.420	0.580	0.000
E50.8 Other manifestations of vitamin A deficiency	0.420	0.580	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.420	0.580	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.420	0.580	0.000
E50.5 Vitamin A deficiency with night blindness	0.420	0.580	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.420	0.580	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.420	0.580	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.420	0.580	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.420	0.580	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.420	0.580	0.000
E56.9 Vitamin deficiency, unspecified	0.420	0.580	0.000
E56.8 Deficiency of other vitamins	0.420	0.580	0.000
E56.1 Deficiency of vitamin K	0.420	0.580	0.000
E56.0 Deficiency of vitamin E	0.420	0.580	0.000
E63.9 Nutritional deficiency, unspecified	0.420	0.580	0.000
E63.8 Other specified nutritional deficiencies	0.420	0.580	0.000
E63.1 Imbalance of constituents of food intake	0.420	0.580	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.420	0.580	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.420	0.580	0.000
E64.8 Sequelae of other nutritional deficiencies	0.420	0.580	0.000
E64.3 Sequelae of rickets	0.420	0.580	0.000
E64.2 Sequelae of vitamin C deficiency	0.420	0.580	0.000
E64.1 Sequelae of vitamin A deficiency	0.420	0.580	0.000
E64.0 Sequelae of protein-energy malnutrition	0.420	0.580	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.419	0.581	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.419	0.581	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.419	0.581	0.000
E53.1 Pyridoxine deficiency	0.417	0.583	0.000
E53.0 Riboflavin deficiency	0.417	0.583	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.417	0.583	0.000
M22.2 Patellofemoral disorders	0.416	0.584	0.000
M86.9 Osteomyelitis, unspecified	0.415	0.585	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.414	0.585	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.414	0.586	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.414	0.586	0.000
M12.2 Villonodular synovitis (pigmented)	0.414	0.586	0.000
M22.0 Recurrent dislocation of patella	0.413	0.586	0.000
E26.9 Hyperaldosteronism, unspecified	0.412	0.587	0.000
E26.8 Other hyperaldosteronism	0.412	0.587	0.000
E26.1 Secondary hyperaldosteronism	0.412	0.587	0.000
M02 Reactive arthropathies	0.412	0.588	0.000
M23.37 Other meniscus derangements-Capsular lig	0.412	0.588	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.410	0.590	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.410	0.590	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.409	0.591	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.409	0.591	0.000
M07.6 Other enteropathic arthropathies	0.408	0.592	0.000
M07.5 Arthropathy in ulcerative colitis	0.408	0.592	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.408	0.592	0.000
M07.2 Psoriatic spondylitis	0.408	0.592	0.000
M07.1 Arthritis mutilans	0.408	0.592	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.408	0.592	0.000
M21.0 Valgus deformity, not elsewhere classified	0.408	0.592	0.000
M12.3 Palindromic rheumatism	0.407	0.593	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.407	0.593	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.407	0.593	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.406	0.593	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.406	0.593	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.406	0.593	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.406	0.594	0.000
M87.3 Other secondary osteonecrosis	0.405	0.595	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.405	0.595	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.405	0.595	0.000
M23.1 Discoid meniscus (congenital)	0.404	0.596	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.403	0.597	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.599	0.401
M88 Paget's disease of bone [osteitis deformans]	0.400	0.599	0.000
M87.2 Osteonecrosis due to previous trauma	0.399	0.601	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.397	0.603	0.000
# Top node	0.397	0.603	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.396	0.604	0.000
M24 Other specific joint derangements	0.396	0.604	0.000
E14.9 Without complications	0.393	0.607	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.393	0.607	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.392	0.608	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.391	0.609	0.000
M61 Calcification and ossification of muscle	0.391	0.609	0.000
E28.9 Ovarian dysfunction, unspecified	0.390	0.609	0.000
E28.8 Other ovarian dysfunction	0.390	0.609	0.000
E28.1 Androgen excess	0.390	0.609	0.000
E28.0 Oestrogen excess	0.390	0.609	0.000
E83 Disorders of mineral metabolism	0.346	0.609	0.045
E28.3 Primary ovarian failure	0.389	0.611	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.385	0.614	0.000
M12.5 Traumatic arthropathy	0.385	0.614	0.000
M12.4 Intermittent hydrarthrosis	0.385	0.614	0.000
M12.1 Kaschin-Beck disease	0.385	0.614	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.385	0.614	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.385	0.615	0.000
M40-M43 Deforming dorsopathies	0.384	0.615	0.000
K51.4 Pseudopolyposis of colon	0.000	0.616	0.384
M33.9 Dermatopolymyositis, unspecified	0.383	0.617	0.000
M33.0 Juvenile dermatomyositis	0.383	0.617	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.383	0.617	0.000
M31.0 Hypersensitivity angiitis	0.382	0.618	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.382	0.618	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.382	0.618	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.382	0.618	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.381	0.619	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.381	0.619	0.000
M23.07 Cystic meniscus-Capsular lig	0.381	0.619	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.381	0.619	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.381	0.619	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.381	0.619	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.381	0.619	0.000
M23.00 Cystic meniscus (Multiple sites)	0.381	0.619	0.000
D80-D89 Certain disorders involving the immune mechanism	0.381	0.619	0.000
M86.8 Other osteomyelitis	0.381	0.619	0.000
M30 Polyarteritis nodosa and related conditions	0.380	0.619	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.381	0.619	0.000
M89 Other disorders of bone	0.380	0.620	0.000
M14.6 Neuropathic arthropathy	0.378	0.622	0.000
E24.0 Pituitary-dependent Cushing's disease	0.377	0.623	0.000
D86 Sarcoidosis	0.377	0.623	0.000
M22.1 Recurrent subluxation of patella	0.377	0.623	0.000
M22.9 Disorder of patella, unspecified	0.377	0.623	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.375	0.624	0.000
E45 Retarded development following protein-energy malnutrition	0.375	0.624	0.000
E43 Unspecified severe protein-energy malnutrition	0.375	0.624	0.000
E42 Marasmic kwashiorkor	0.375	0.624	0.000
E41 Nutritional marasmus	0.375	0.624	0.000
E40 Kwashiorkor	0.375	0.624	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.624	0.376
E22.0 Acromegaly and pituitary gigantism	0.375	0.624	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.376	0.624	0.000
M33.2 Polymyositis	0.375	0.625	0.000
M60 Myositis	0.374	0.626	0.000
M62.6 Muscle strain	0.373	0.627	0.000
E53.8 Deficiency of other specified B group vitamins	0.372	0.628	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.371	0.629	0.000
M32.8 Other forms of systemic lupus erythematosus	0.371	0.629	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations