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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116561927
log Bayes Factor = 21.8507
Chromosome 2   position 221,679,348  (GRCh37) Explore rs116561927 on Ensembl!
Variant rs116561927 is part of Cluster X0192

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
H25-H28 Disorders of lens
1.000 0.000 0.000
H26 Other cataract
1.000 0.000 0.000
H26.9 Cataract, unspecified
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.996 0.004 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
Z30 Contraceptive management
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
J40-J47 Chronic lower respiratory diseases
0.988 0.012 0.000
Z30.2 Sterilisation
0.987 0.013 0.000
J90-J94 Other diseases of pleura
0.987 0.013 0.000
J95-J99 Other diseases of the respiratory system
0.984 0.016 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.978 0.022 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.978 0.022 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.978 0.022 0.000
Chapter VI Diseases of the nervous system
0.972 0.028 0.000
J98 Other respiratory disorders
0.970 0.030 0.000
J90 Pleural effusion, not elsewhere classified
0.965 0.035 0.000
S70-S79 Injuries to the hip and thigh
0.962 0.038 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.958 0.042 0.000
J98.1 Pulmonary collapse
0.954 0.046 0.000
H30-H36 Disorders of choroid and retina
0.949 0.051 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.947 0.053 0.000
Z88.0 Personal history of allergy to penicillin
0.942 0.058 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.941 0.059 0.000
Z95.4 Presence of other heart-valve replacement
0.939 0.061 0.000
Z93 Artificial opening status
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.937 0.063 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.933 0.067 0.000
M70-M79 Other soft tissue disorders
0.928 0.072 0.000
Z34 Supervision of normal pregnancy
0.922 0.078 0.000
Z83 Family history of other specific disorders
0.921 0.079 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.919 0.081 0.000
S00-S09 Injuries to the head
0.919 0.081 0.000
S50-S59 Injuries to the elbow and forearm
0.918 0.082 0.000
M75 Shoulder lesions
0.914 0.086 0.000
J46 Status asthmaticus
0.913 0.087 0.000
S72 Fracture of femur
0.911 0.089 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.911 0.089 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.910 0.090 0.000
J43 Emphysema
0.909 0.091 0.000
R41.0 Disorientation, unspecified
0.909 0.091 0.000
H26.4 After-cataract
0.906 0.094 0.000
C60-C63 Malignant neoplasms of male genital organs
0.905 0.094 0.000
J30-J39 Other diseases of upper respiratory tract
0.904 0.096 0.000
G90-G99 Other disorders of the nervous system
0.902 0.098 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.901 0.099 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.899 0.101 0.000
Chapter IX Diseases of the circulatory system
0.897 0.103 0.000
H35 Other retinal disorders
0.897 0.103 0.000
Chapter XXII Codes for special purposes
0.897 0.103 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.897 0.103 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.896 0.104 0.000
I30-I52 Other forms of heart disease
0.892 0.108 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.891 0.109 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.890 0.110 0.000
Z80 Family history of malignant neoplasm
0.888 0.112 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.885 0.115 0.000
M75.0 Adhesive capsulitis of shoulder
0.883 0.117 0.000
I35 Nonrheumatic aortic valve disorders
0.883 0.117 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.883 0.117 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.881 0.119 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.880 0.120 0.000
W00-W19 Falls
0.877 0.123 0.000
J32 Chronic sinusitis
0.877 0.123 0.000
S60-S69 Injuries to the wrist and hand
0.876 0.124 0.000
Z93.6 Other artificial openings of urinary tract status
0.875 0.125 0.000
J09-J18 Influenza and pneumonia
0.871 0.129 0.000
H25 Senile cataract
0.869 0.131 0.000
C51-C58 Malignant neoplasms of female genital organs
0.864 0.136 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.864 0.136 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.862 0.138 0.000
S72.0 Fracture of neck of femur
0.860 0.140 0.000
A00-A09 Intestinal infectious diseases
0.860 0.140 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.858 0.142 0.000
H33 Retinal detachments and breaks
0.855 0.145 0.000
M75.4 Impingement syndrome of shoulder
0.855 0.145 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.854 0.146 0.000
C61 Malignant neoplasm of prostate
0.853 0.147 0.000
S06 Intracranial injury
0.852 0.148 0.000
J43.9 Emphysema, unspecified
0.852 0.148 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.850 0.150 0.000
J42 Unspecified chronic bronchitis
0.849 0.151 0.000
O41 Other disorders of amniotic fluid and membranes
0.848 0.152 0.000
I35.0 Aortic (valve) stenosis
0.848 0.152 0.000
M20-M25 Other joint disorders
0.847 0.153 0.000
J60-J70 Lung diseases due to external agents
0.846 0.154 0.000
R50-R69 General symptoms and signs
0.845 0.155 0.000
I05-I09 Chronic rheumatic heart diseases
0.843 0.157 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.843 0.157 0.000
B95-B98 Bacterial, viral and other infectious agents
0.843 0.157 0.000
Z94 Transplanted organ and tissue status
0.841 0.159 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.839 0.161 0.000
R50 Fever of unknown origin
0.836 0.164 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.835 0.165 0.000
O36 Maternal care for other known or suspected foetal problems
0.835 0.165 0.000
Z12 Special screening examination for neoplasms
0.834 0.166 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.829 0.171 0.000
C43 Malignant melanoma of skin
0.827 0.173 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.826 0.174 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.825 0.175 0.000
S72.00 Fracture of neck of femur (closed)
0.823 0.177 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.822 0.178 0.000
H18 Other disorders of cornea
0.822 0.178 0.000
Z96 Presence of other functional implants
0.821 0.179 0.000
R50.9 Fever, unspecified
0.821 0.179 0.000
S90-S99 Injuries to the ankle and foot
0.820 0.180 0.000
S52 Fracture of forearm
0.818 0.182 0.000
J44 Other chronic obstructive pulmonary disease
0.816 0.184 0.000
M65-M68 Disorders of synovium and tendon
0.816 0.184 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.816 0.184 0.000
H43-H45 Disorders of vitreous body and globe
0.816 0.184 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.813 0.187 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.813 0.187 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.812 0.188 0.000
O00-O08 Pregnancy with abortive outcome
0.811 0.189 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.810 0.190 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.810 0.190 0.000
S40-S49 Injuries to the shoulder and upper arm
0.809 0.191 0.000
I08 Multiple valve diseases
0.808 0.192 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.808 0.192 0.000
M20 Acquired deformities of fingers and toes
0.808 0.192 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.806 0.194 0.000
G20-G26 Extrapyramidal and movement disorders
0.804 0.196 0.000
Z83.7 Family history of diseases of the digestive system
0.804 0.196 0.000
Z34.8 Supervision of other normal pregnancy
0.802 0.198 0.000
H27 Other disorders of lens
0.802 0.198 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.801 0.199 0.000
J98.4 Other disorders of lung
0.800 0.200 0.000
R60 Oedema, not elsewhere classified
0.799 0.201 0.000
J32.9 Chronic sinusitis, unspecified
0.798 0.202 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.798 0.202 0.000
T66-T78 Other and unspecified effects of external causes
0.797 0.203 0.000
O26.8 Other specified pregnancy-related conditions
0.795 0.205 0.000
J32.0 Chronic maxillary sinusitis
0.794 0.206 0.000
O47 False labour
0.791 0.209 0.000
T93 Sequelae of injuries of lower limb
0.791 0.209 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.790 0.210 0.000
S01 Open wound of head
0.788 0.212 0.000
W50-W64 Exposure to animate mechanical forces
0.786 0.214 0.000
I35.1 Aortic (valve) insufficiency
0.785 0.215 0.000
Z93.3 Colostomy status
0.784 0.216 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.783 0.217 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.783 0.217 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.783 0.217 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.783 0.217 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.783 0.217 0.000
S71 Open wound of hip and thigh
0.781 0.219 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.781 0.219 0.000
J94 Other pleural conditions
0.779 0.221 0.000
D00-D09 In situ neoplasms
0.778 0.222 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.777 0.223 0.000
Z83.3 Family history of diabetes mellitus
0.777 0.223 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.776 0.223 0.000
Z96.1 Presence of intraocular lens
0.776 0.224 0.000
V80-V89 Other land transport accidents
0.775 0.225 0.000
H35.3 Degeneration of macula and posterior pole
0.775 0.225 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.775 0.225 0.000
Z02 Examination and encounter for administrative purposes
0.773 0.227 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.773 0.227 0.000
O30 Multiple gestation
0.773 0.227 0.000
W19 Unspecified fall
0.773 0.227 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.772 0.228 0.000
Z95.1 Presence of aortocoronary bypass graft
0.771 0.229 0.000
J91 Pleural effusion in conditions classified elsewhere
0.771 0.229 0.000
J92 Pleural plaque
0.770 0.230 0.000
H33.2 Serous retinal detachment
0.770 0.230 0.000
S20-S29 Injuries to the thorax
0.768 0.232 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.768 0.232 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.767 0.233 0.000
S51 Open wound of forearm
0.767 0.233 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.765 0.235 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.765 0.235 0.000
H35.0 Background retinopathy and retinal vascular changes
0.765 0.235 0.000
H35.2 Other proliferative retinopathy
0.763 0.237 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.763 0.237 0.000
Z84 Family history of other conditions
0.763 0.237 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.762 0.238 0.000
G62 Other polyneuropathies
0.758 0.241 0.000
Z86 Personal history of certain other diseases
0.758 0.242 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.755 0.245 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.755 0.245 0.000
V20-V29 Motorcycle rider injured in transport accident
0.755 0.245 0.000
Z63 Other problems related to primary support group, including family circumstances
0.755 0.245 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.755 0.245 0.000
C15-C26 Malignant neoplasms of digestive organs
0.754 0.246 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.753 0.247 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.753 0.247 0.000
H25.0 Senile incipient cataract
0.751 0.249 0.000
J81 Pulmonary oedema
0.751 0.249 0.000
O32.1 Maternal care for breech presentation
0.751 0.249 0.000
T86 Failure and rejection of transplanted organs and tissues
0.750 0.250 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.749 0.251 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.749 0.251 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.749 0.251 0.000
C01 Malignant neoplasm of base of tongue
0.748 0.252 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.747 0.253 0.000
Z97 Presence of other devices
0.747 0.253 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.747 0.253 0.000
C64-C68 Malignant neoplasms of urinary tract
0.747 0.253 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.747 0.253 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.745 0.255 0.000
G40-G47 Episodic and paroxysmal disorders
0.745 0.255 0.000
H53-H54 Visual disturbances and blindness
0.744 0.256 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.743 0.257 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.743 0.257 0.000
S79 Other and unspecified injuries of hip and thigh
0.742 0.257 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.742 0.258 0.000
T79-T79 Certain early complications of trauma
0.742 0.258 0.000
G93 Other disorders of brain
0.742 0.258 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.741 0.259 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.740 0.260 0.000
H25.1 Senile nuclear cataract
0.739 0.261 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.739 0.261 0.000
J40 Bronchitis, not specified as acute or chronic
0.738 0.262 0.000
I50 Heart failure
0.738 0.262 0.000
I49 Other cardiac arrhythmias
0.737 0.263 0.000
S02 Fracture of skull and facial bones
0.735 0.265 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.732 0.268 0.000
G91 Hydrocephalus
0.731 0.269 0.000
M20.4 Other hammer toe(s) (acquired)
0.729 0.271 0.000
S06.5 Traumatic subdural haemorrhage
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.727 0.273 0.000
J69 Pneumonitis due to solids and liquids
0.727 0.273 0.000
R60.0 Localised oedema
0.726 0.274 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.726 0.274 0.000
W19.4 Street and highway
0.725 0.275 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.725 0.275 0.000
M65 Synovitis and tenosynovitis
0.724 0.276 0.000
T90 Sequelae of injuries of head
0.724 0.276 0.000
S06.0 Concussion
0.724 0.276 0.000
M75.1 Rotator cuff syndrome
0.724 0.276 0.000
J30 Vasomotor and allergic rhinitis
0.724 0.276 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.723 0.277 0.000
M71 Other bursopathies
0.722 0.278 0.000
G70-G73 Diseases of myoneural junction and muscle
0.719 0.280 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.718 0.282 0.000
B99-B99 Other infectious diseases
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.717 0.283 0.000
H26.3 Drug-induced cataract
0.717 0.283 0.000
H26.2 Complicated cataract
0.717 0.283 0.000
H26.1 Traumatic cataract
0.717 0.283 0.000
H26.0 Infantile, juvenile and presenile cataract
0.717 0.283 0.000
R40 Somnolence, stupor and coma
0.716 0.284 0.000
I44 Atrioventricular and left bundle-branch block
0.716 0.284 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.716 0.284 0.000
M75.9 Shoulder lesion, unspecified
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
O60-O75 Complications of labour and delivery
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
S72.1 Pertrochanteric fracture
0.714 0.286 0.000
J93 Pneumothorax
0.714 0.286 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.714 0.286 0.000
I42 Cardiomyopathy
0.714 0.286 0.000
Z38 Liveborn infants according to place of birth
0.714 0.286 0.000
Z32 Pregnancy examination and test
0.714 0.286 0.000
Z31 Procreative management
0.714 0.286 0.000
O36.5 Maternal care for poor foetal growth
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.712 0.288 0.000
M86-M90 Other osteopathies
0.712 0.288 0.000
Z30.9 Contraceptive management, unspecified
0.711 0.288 0.000
Z30.8 Other contraceptive management
0.711 0.288 0.000
Z30.4 Surveillance of contraceptive drugs
0.711 0.288 0.000
Z30.3 Menstrual extraction
0.711 0.288 0.000
Z30.0 General counselling and advice on contraception
0.711 0.288 0.000
O03 Spontaneous abortion
0.711 0.289 0.000
C20 Malignant neoplasm of rectum
0.711 0.289 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.711 0.289 0.000
C45 Mesothelioma
0.711 0.289 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.710 0.290 0.000
M24 Other specific joint derangements
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.290 0.000
Y10-Y34 Event of undetermined intent
0.709 0.290 0.000
Y00-Y09 Assault
0.709 0.290 0.000
X85-X99 Assault
0.709 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.290 0.000
X50-X57 Overexertion, travel and privation
0.709 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.290 0.000
X30-X39 Exposure to forces of nature
0.709 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.290 0.000
X10-X19 Contact with heat and hot substances
0.709 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.290 0.000
W75-W84 Other accidental threats to breathing
0.709 0.290 0.000
W65-W74 Accidental drowning and submersion
0.709 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.290 0.000
V95-V97 Air and space transport accidents
0.709 0.290 0.000
V90-V94 Water transport accidents
0.709 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.709 0.291 0.000
J41 Simple and mucopurulent chronic bronchitis
0.708 0.291 0.000
S01.1 Open wound of eyelid and periocular area
0.708 0.292 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.708 0.292 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.707 0.293 0.000
C54 Malignant neoplasm of corpus uteri
0.707 0.293 0.000
J18 Pneumonia, organism unspecified
0.707 0.293 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.707 0.293 0.000
H10-H13 Disorders of conjunctiva
0.706 0.293 0.000
Z95.2 Presence of prosthetic heart valve
0.706 0.294 0.000
O80-O84 Delivery
0.706 0.294 0.000
C04 Malignant neoplasm of floor of mouth
0.706 0.294 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.706 0.294 0.000
J96 Respiratory failure, not elsewhere classified
0.706 0.294 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
Z60 Problems related to social environment
0.704 0.296 0.000
G25 Other extrapyramidal and movement disorders
0.704 0.296 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.704 0.296 0.000
S62 Fracture at wrist and hand level
0.704 0.296 0.000
H18.5 Hereditary corneal dystrophies
0.703 0.297 0.000
S92 Fracture of foot, except ankle
0.702 0.298 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.701 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.701 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
O45 Premature separation of placenta [abruptio placentae]
0.701 0.299 0.000
O44 Placenta praevia
0.701 0.299 0.000
O43 Placental disorders
0.701 0.299 0.000
O33 Maternal care for known or suspected disproportion
0.701 0.299 0.000
O31 Complications specific to multiple gestation
0.701 0.299 0.000
O40 Polyhydramnios
0.701 0.299 0.000
I30 Acute pericarditis
0.701 0.299 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.701 0.299 0.000
Z89 Acquired absence of limb
0.700 0.299 0.000
Z29 Need for other prophylactic measures
0.700 0.300 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.700 0.300 0.000
S80-S89 Injuries to the knee and lower leg
0.699 0.301 0.000
H52 Disorders of refraction and accommodation
0.698 0.302 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.697 0.303 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.697 0.303 0.000
R60.9 Oedema, unspecified
0.697 0.303 0.000
J98.9 Respiratory disorder, unspecified
0.696 0.304 0.000
J98.8 Other specified respiratory disorders
0.696 0.304 0.000
J98.6 Disorders of diaphragm
0.696 0.304 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.696 0.304 0.000
J98.3 Compensatory emphysema
0.696 0.304 0.000
J98.2 Interstitial emphysema
0.696 0.304 0.000
R22.0 Localised swelling, mass and lump, head
0.696 0.304 0.000
Z88.2 Personal history of allergy to sulphonamides
0.695 0.304 0.000
Z83.5 Family history of eye and ear disorders
0.695 0.305 0.000
A02 Other Salmonella infections
0.694 0.306 0.000
H20 Iridocyclitis
0.694 0.306 0.000
Z02.8 Other examinations for administrative purposes
0.693 0.307 0.000
Z87 Personal history of other diseases and conditions
0.693 0.307 0.000
J32.8 Other chronic sinusitis
0.692 0.308 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.692 0.308 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.309 0.000
H16 Keratitis
0.691 0.309 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.690 0.310 0.000
Z95.3 Presence of xenogenic heart valve
0.690 0.310 0.000
C51 Malignant neoplasm of vulva
0.690 0.310 0.000
S78 Traumatic amputation of hip and thigh
0.690 0.310 0.000
S77 Crushing injury of hip and thigh
0.690 0.310 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.690 0.310 0.000
S75 Injury of blood vessels at hip and thigh level
0.690 0.310 0.000
S74 Injury of nerves at hip and thigh level
0.690 0.310 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.690 0.310 0.000
S70 Superficial injury of hip and thigh
0.690 0.310 0.000
Z93.5 Cystostomy status
0.690 0.310 0.000
O46.9 Antepartum haemorrhage, unspecified
0.690 0.310 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.690 0.310 0.000
I31 Other diseases of pericardium
0.689 0.311 0.000
O32.0 Maternal care for unstable lie
0.689 0.311 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.688 0.312 0.000
Z93.1 Gastrostomy status
0.688 0.312 0.000
I50.1 Left ventricular failure
0.688 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.313 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.687 0.313 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.687 0.313 0.000
X60-X84 Intentional self-harm
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.687 0.313 0.000
H33.0 Retinal detachment with retinal break
0.686 0.314 0.000
Z94.4 Liver transplant status
0.686 0.314 0.000
I36 Nonrheumatic tricuspid valve disorders
0.686 0.314 0.000
A30-A49 Other bacterial diseases
0.686 0.314 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.684 0.316 0.000
M77 Other enthesopathies
0.683 0.317 0.000
Z94.7 Corneal transplant status
0.683 0.317 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.683 0.317 0.000
D46 Myelodysplastic syndromes
0.681 0.319 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.681 0.319 0.000
J36 Peritonsillar abscess
0.681 0.319 0.000
R50.0 Fever with chills
0.680 0.320 0.000
M21 Other acquired deformities of limbs
0.680 0.320 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.680 0.320 0.000
H31 Other disorders of choroid
0.680 0.320 0.000
H30 Chorioretinal inflammation
0.680 0.320 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.680 0.320 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.679 0.321 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.679 0.321 0.000
S52.0 Fracture of upper end of ulna
0.679 0.321 0.000
M60-M63 Disorders of muscles
0.679 0.321 0.000
M00-M03 Infectious arthropathies
0.679 0.321 0.000
A80-A89 Viral infections of the central nervous system
0.678 0.321 0.000
C43.9 Malignant melanoma of skin, unspecified
0.678 0.322 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.677 0.323 0.000
I51 Complications and ill-defined descriptions of heart disease
0.677 0.323 0.000
S64 Injury of nerves at wrist and hand level
0.677 0.323 0.000
Z33 Pregnant state, incidental
0.675 0.325 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.675 0.325 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.675 0.325 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.675 0.325 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.675 0.325 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.675 0.325 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.675 0.325 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.675 0.325 0.000
R50.8 Other specified fever
0.674 0.326 0.000
S72.4 Fracture of lower end of femur
0.674 0.326 0.000
H43 Disorders of vitreous body
0.674 0.326 0.000
M40-M43 Deforming dorsopathies
0.674 0.326 0.000
Z86.7 Personal history of diseases of the circulatory system
0.673 0.327 0.000
Z93.0 Tracheostomy status
0.673 0.327 0.000
M91-M94 Chondropathies
0.673 0.327 0.000
W20-W49 Exposure to inanimate mechanical forces
0.673 0.327 0.000
Z93.9 Artificial opening status, unspecified
0.672 0.327 0.000
Z93.8 Other artificial opening status
0.672 0.327 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.672 0.327 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.672 0.328 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.672 0.328 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.672 0.328 0.000
B65-B83 Helminthiases
0.672 0.328 0.000
B50-B64 Protozoal diseases
0.672 0.328 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.672 0.328 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.672 0.328 0.000
A75-A79 Rickettsioses
0.672 0.328 0.000
A70-A74 Other diseases caused by chlamydiae
0.672 0.328 0.000
A65-A69 Other spirochaetal diseases
0.672 0.328 0.000
A20-A28 Certain zoonotic bacterial diseases
0.672 0.328 0.000
A15-A19 Tuberculosis
0.672 0.328 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.671 0.329 0.000
D45 Polycythaemia vera
0.671 0.329 0.000
M20.1 Hallux valgus (acquired)
0.671 0.329 0.000
S01.8 Open wound of other parts of head
0.671 0.329 0.000
Chapter V Mental and behavioural disorders
0.671 0.329 0.000
O24 Diabetes mellitus in pregnancy
0.670 0.330 0.000
C67 Malignant neoplasm of bladder
0.670 0.330 0.000
V10-V19 Pedal cyclist injured in transport accident
0.670 0.330 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.670 0.330 0.000
D41.4 Bladder
0.669 0.330 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.669 0.331 0.000
D37.4 Colon
0.669 0.331 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.669 0.331 0.000
S42 Fracture of shoulder and upper arm
0.669 0.331 0.000
I44.2 Atrioventricular block, complete
0.669 0.331 0.000
G62.9 Polyneuropathy, unspecified
0.668 0.332 0.000
O36.8 Maternal care for other specified foetal problems
0.668 0.332 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.667 0.333 0.000
Z94.0 Kidney transplant status
0.667 0.333 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.667 0.333 0.000
Z13 Special screening examination for other diseases and disorders
0.666 0.334 0.000
Y86 Sequelae of other accidents
0.666 0.334 0.000
J45 Asthma
0.666 0.334 0.000
M76 Enthesopathies of lower limb, excluding foot
0.665 0.334 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.665 0.334 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.665 0.335 0.000
T85.2 Mechanical complication of intraocular lens
0.665 0.335 0.000
D37.5 Rectum
0.664 0.335 0.000
H33.5 Other retinal detachments
0.663 0.336 0.000
Y52 Agents primarily affecting the cardiovascular system
0.662 0.338 0.000
I34 Nonrheumatic mitral valve disorders
0.661 0.339 0.000
J80 Adult respiratory distress syndrome
0.661 0.339 0.000
W07 Fall involving chair
0.661 0.339 0.000
Z34.0 Supervision of normal first pregnancy
0.661 0.339 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.661 0.339 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.661 0.339 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.661 0.339 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.660 0.340 0.000
Z83.6 Family history of diseases of the respiratory system
0.660 0.340 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.660 0.340 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.660 0.340 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.660 0.340 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.660 0.340 0.000
H27.0 Aphakia
0.660 0.340 0.000
I35.9 Aortic valve disorder, unspecified
0.660 0.340 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.659 0.341 0.000
R46 Symptoms and signs involving appearance and behaviour
0.659 0.341 0.000
R43 Disturbances of smell and taste
0.659 0.341 0.000
S08 Traumatic amputation of part of head
0.659 0.341 0.000
S07 Crushing injury of head
0.659 0.341 0.000
S05 Injury of eye and orbit
0.659 0.341 0.000
S04 Injury of cranial nerves
0.659 0.341 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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