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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116775899
log Bayes Factor = 12.2053
Chromosome 5   position 76,143,246  (GRCh37) Explore rs116775899 on Ensembl!
Variant rs116775899 is part of Cluster X0142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
L03 Cellulitis
0.997 0.003 0.000
L03.1 Cellulitis of other parts of limb
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.992 0.008 0.000
N17-N19 Renal failure
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.990 0.010 0.000
N18 Chronic renal failure
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
N18.3 Chronic kidney disease, stage 3
0.978 0.022 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.976 0.024 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.966 0.034 0.000
D50-D53 Nutritional anaemias
0.966 0.034 0.000
H90-H95 Other disorders of ear
0.962 0.038 0.000
S60-S69 Injuries to the wrist and hand
0.958 0.042 0.000
A00-A09 Intestinal infectious diseases
0.957 0.043 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.953 0.047 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.951 0.049 0.000
G40-G47 Episodic and paroxysmal disorders
0.950 0.050 0.000
D80-D89 Certain disorders involving the immune mechanism
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
I20-I25 Ischaemic heart diseases
0.946 0.054 0.000
I95 Hypotension
0.945 0.055 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.945 0.055 0.000
D60-D64 Aplastic and other anaemias
0.940 0.060 0.000
M05-M14 Inflammatory polyarthropathies
0.936 0.064 0.000
A04 Other bacterial intestinal infections
0.932 0.068 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.930 0.070 0.000
I20 Angina pectoris
0.929 0.071 0.000
N18.9 Chronic renal failure, unspecified
0.928 0.072 0.000
G47 Sleep disorders
0.928 0.072 0.000
H65-H75 Diseases of middle ear and mastoid
0.925 0.075 0.000
I95.9 Hypotension, unspecified
0.923 0.077 0.000
I20.0 Unstable angina
0.922 0.078 0.000
M65-M68 Disorders of synovium and tendon
0.918 0.082 0.000
G51 Facial nerve disorders
0.918 0.082 0.000
M20-M25 Other joint disorders
0.914 0.086 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.911 0.089 0.000
T17 Foreign body in respiratory tract
0.910 0.090 0.000
D86 Sarcoidosis
0.907 0.093 0.000
L50-L54 Urticaria and erythema
0.906 0.094 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.906 0.094 0.000
I30-I52 Other forms of heart disease
0.904 0.096 0.000
N17 Acute renal failure
0.903 0.097 0.000
G57 Mononeuropathies of lower limb
0.898 0.102 0.000
N30-N39 Other diseases of urinary system
0.898 0.102 0.000
M10 Gout
0.895 0.105 0.000
I51 Complications and ill-defined descriptions of heart disease
0.894 0.106 0.000
G56 Mononeuropathies of upper limb
0.893 0.107 0.000
M80-M85 Disorders of bone density and structure
0.890 0.110 0.000
A04.8 Other specified bacterial intestinal infections
0.887 0.113 0.000
E50-E64 Other nutritional deficiencies
0.886 0.113 0.000
G90-G99 Other disorders of the nervous system
0.880 0.120 0.000
M23 Internal derangement of knee
0.878 0.122 0.000
I22 Subsequent myocardial infarction
0.877 0.123 0.000
L05 Pilonidal cyst
0.876 0.124 0.000
L60-L75 Disorders of skin appendages
0.875 0.125 0.000
M23.3 Other meniscus derangements
0.872 0.128 0.000
G51.0 Bell's palsy
0.871 0.129 0.000
G47.9 Sleep disorder, unspecified
0.869 0.131 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.868 0.132 0.000
B15-B19 Viral hepatitis
0.867 0.133 0.000
M65 Synovitis and tenosynovitis
0.866 0.134 0.000
M10.9 Gout, unspecified
0.865 0.135 0.000
I42 Cardiomyopathy
0.865 0.135 0.000
N39 Other disorders of urinary system
0.857 0.143 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.856 0.144 0.000
I51.8 Other ill-defined heart diseases
0.855 0.145 0.000
L08 Other local infections of skin and subcutaneous tissue
0.851 0.149 0.000
E10-E14 Diabetes mellitus
0.849 0.151 0.000
M06 Other rheumatoid arthritis
0.848 0.152 0.000
N60-N64 Disorders of breast
0.846 0.154 0.000
L53 Other erythematous conditions
0.845 0.155 0.000
H92 Otalgia and effusion of ear
0.843 0.157 0.000
N17.9 Acute renal failure, unspecified
0.841 0.159 0.000
S62 Fracture at wrist and hand level
0.839 0.161 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.838 0.162 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.836 0.164 0.000
H91 Other hearing loss
0.835 0.164 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.835 0.165 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.834 0.166 0.000
I51.9 Heart disease, unspecified
0.833 0.167 0.000
D51 Vitamin B12 deficiency anaemia
0.833 0.167 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.833 0.167 0.000
T17.2 Foreign body in pharynx
0.832 0.168 0.000
L03.2 Cellulitis of face
0.831 0.169 0.000
D52 Folate deficiency anaemia
0.831 0.169 0.000
I95.2 Hypotension due to drugs
0.829 0.171 0.000
G47.3 Sleep apnoea
0.825 0.175 0.000
E10 Insulin-dependent diabetes mellitus
0.823 0.177 0.000
G57.6 Lesion of plantar nerve
0.823 0.177 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.823 0.177 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.820 0.180 0.000
Y44 Agents primarily affecting blood constituents
0.819 0.181 0.000
N25-N29 Other disorders of kidney and ureter
0.819 0.181 0.000
A30-A49 Other bacterial diseases
0.815 0.185 0.000
H72 Perforation of tympanic membrane
0.814 0.186 0.000
S67 Crushing injury of wrist and hand
0.814 0.186 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.812 0.188 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.812 0.188 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.810 0.190 0.000
S10-S19 Injuries to the neck
0.810 0.190 0.000
E20-E35 Disorders of other endocrine glands
0.809 0.191 0.000
E10.9 Without complications
0.808 0.192 0.000
D50 Iron deficiency anaemia
0.806 0.194 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.805 0.195 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.803 0.197 0.000
L53.9 Erythematous condition, unspecified
0.802 0.198 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.801 0.199 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.801 0.199 0.000
G62 Other polyneuropathies
0.800 0.200 0.000
G70-G73 Diseases of myoneural junction and muscle
0.800 0.200 0.000
G56.0 Carpal tunnel syndrome
0.800 0.200 0.000
D64 Other anaemias
0.799 0.200 0.000
D53 Other nutritional anaemias
0.798 0.202 0.000
E53 Deficiency of other B group vitamins
0.797 0.202 0.000
A08 Viral and other specified intestinal infections
0.797 0.203 0.000
M10.99 Gout, unspecified (Site unspecified)
0.793 0.207 0.000
D86.9 Sarcoidosis, unspecified
0.792 0.208 0.000
H90 Conductive and sensorineural hearing loss
0.792 0.208 0.000
L03.0 Cellulitis of finger and toe
0.790 0.210 0.000
B35-B49 Mycoses
0.788 0.212 0.000
G30-G32 Other degenerative diseases of the nervous system
0.781 0.219 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.781 0.219 0.000
D63.0 Anaemia in neoplastic disease
0.780 0.220 0.000
D61 Other aplastic anaemias
0.779 0.221 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.778 0.222 0.000
N39.9 Disorder of urinary system, unspecified
0.777 0.223 0.000
L73 Other follicular disorders
0.777 0.223 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.774 0.226 0.000
D86.8 Sarcoidosis of other and combined sites
0.768 0.232 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.767 0.233 0.000
N39.8 Other specified disorders of urinary system
0.767 0.233 0.000
H60-H62 Diseases of external ear
0.767 0.233 0.000
G93 Other disorders of brain
0.767 0.233 0.000
M24 Other specific joint derangements
0.767 0.233 0.000
E55 Vitamin D deficiency
0.766 0.234 0.000
N18.8 Other chronic renal failure
0.766 0.234 0.000
M06.9 Rheumatoid arthritis, unspecified
0.766 0.234 0.000
X60-X84 Intentional self-harm
0.765 0.235 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.237 0.000
S61 Open wound of wrist and hand
0.763 0.237 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
W50-W64 Exposure to animate mechanical forces
0.761 0.239 0.000
S64 Injury of nerves at wrist and hand level
0.760 0.240 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.760 0.240 0.000
Y52 Agents primarily affecting the cardiovascular system
0.760 0.240 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.759 0.241 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.759 0.241 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
H74 Other disorders of middle ear and mastoid
0.759 0.241 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.758 0.242 0.000
G40 Epilepsy
0.757 0.243 0.000
M22 Disorders of patella
0.757 0.243 0.000
I60-I69 Cerebrovascular diseases
0.756 0.244 0.000
T18 Foreign body in alimentary tract
0.755 0.245 0.000
L03.8 Cellulitis of other sites
0.752 0.248 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.752 0.248 0.000
H93 Other disorders of ear, not elsewhere classified
0.751 0.249 0.000
S62.5 Fracture of thumb
0.750 0.250 0.000
B18 Chronic viral hepatitis
0.748 0.252 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.748 0.252 0.000
N20-N23 Urolithiasis
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.747 0.252 0.000
B99-B99 Other infectious diseases
0.746 0.254 0.000
H91.9 Hearing loss, unspecified
0.745 0.255 0.000
I42.9 Cardiomyopathy, unspecified
0.744 0.256 0.000
N64 Other disorders of breast
0.742 0.258 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.742 0.258 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.742 0.258 0.000
G44 Other headache syndromes
0.741 0.259 0.000
L05.0 Pilonidal cyst with abscess
0.740 0.260 0.000
I95.8 Other hypotension
0.740 0.260 0.000
I42.0 Dilated cardiomyopathy
0.740 0.260 0.000
M00-M03 Infectious arthropathies
0.740 0.260 0.000
D86.1 Sarcoidosis of lymph nodes
0.739 0.261 0.000
Y44.2 Anticoagulants
0.739 0.261 0.000
M81 Osteoporosis without pathological fracture
0.739 0.261 0.000
I24 Other acute ischaemic heart diseases
0.738 0.262 0.000
L60 Nail disorders
0.738 0.262 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.737 0.263 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.737 0.263 0.000
G56.2 Lesion of ulnar nerve
0.735 0.265 0.000
H66 Suppurative and unspecified otitis media
0.734 0.266 0.000
D52.9 Folate deficiency anaemia, unspecified
0.734 0.266 0.000
E53.8 Deficiency of other specified B group vitamins
0.734 0.266 0.000
S50-S59 Injuries to the elbow and forearm
0.734 0.266 0.000
M31 Other necrotising vasculopathies
0.733 0.267 0.000
G41 Status epilepticus
0.733 0.267 0.000
T79-T79 Certain early complications of trauma
0.731 0.269 0.000
H92.0 Otalgia
0.730 0.270 0.000
S80-S89 Injuries to the knee and lower leg
0.729 0.271 0.000
D55-D59 Haemolytic anaemias
0.728 0.272 0.000
M86-M90 Other osteopathies
0.726 0.273 0.000
E70-E90 Metabolic disorders
0.726 0.274 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.726 0.274 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.726 0.274 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.724 0.276 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.724 0.276 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.724 0.276 0.000
G50 Disorders of trigeminal nerve
0.724 0.276 0.000
G54 Nerve root and plexus disorders
0.723 0.277 0.000
S20-S29 Injuries to the thorax
0.723 0.277 0.000
B65-B83 Helminthiases
0.723 0.277 0.000
A04.5 Campylobacter enteritis
0.721 0.279 0.000
M84 Disorders of continuity of bone
0.720 0.279 0.000
B25-B34 Other viral diseases
0.720 0.280 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.720 0.280 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.719 0.281 0.000
A02 Other Salmonella infections
0.718 0.282 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.283 0.000
Y45.0 Opioids and related analgesics
0.716 0.284 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
L04 Acute lymphadenitis
0.716 0.284 0.000
L01 Impetigo
0.716 0.284 0.000
L00 Staphylococcal scalded skin syndrome
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.716 0.284 0.000
L05.9 Pilonidal cyst without abscess
0.715 0.285 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.715 0.285 0.000
D69 Purpura and other haemorrhagic conditions
0.714 0.286 0.000
D86.0 Sarcoidosis of lung
0.713 0.287 0.000
T66-T78 Other and unspecified effects of external causes
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
Y42.7 Androgens and anabolic congeners
0.711 0.289 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.711 0.289 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.711 0.289 0.000
G57.8 Other mononeuropathies of lower limb
0.711 0.289 0.000
B95-B98 Bacterial, viral and other infectious agents
0.710 0.290 0.000
G47.8 Other sleep disorders
0.710 0.290 0.000
G93.3 Postviral fatigue syndrome
0.709 0.291 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.709 0.291 0.000
N18.1 Chronic kidney disease, stage 1
0.708 0.292 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
N18.2 Chronic kidney disease, stage 2
0.706 0.294 0.000
N99-N99 Other disorders of the genitourinary system
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.706 0.294 0.000
G62.9 Polyneuropathy, unspecified
0.705 0.295 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.704 0.296 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.704 0.296 0.000
N39.0 Urinary tract infection, site not specified
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.703 0.297 0.000
T86 Failure and rejection of transplanted organs and tissues
0.703 0.297 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.702 0.298 0.000
L73.9 Follicular disorder, unspecified
0.700 0.300 0.000
G96 Other disorders of central nervous system
0.700 0.300 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.699 0.300 0.000
G52 Disorders of other cranial nerves
0.699 0.300 0.000
I42.2 Other hypertrophic cardiomyopathy
0.699 0.301 0.000
D64.9 Anaemia, unspecified
0.699 0.301 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.698 0.302 0.000
G90 Disorders of autonomic nervous system
0.697 0.303 0.000
M80 Osteoporosis with pathological fracture
0.696 0.304 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.695 0.305 0.000
N61 Inflammatory disorders of breast
0.695 0.305 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.694 0.306 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.694 0.306 0.000
H71 Cholesteatoma of middle ear
0.693 0.307 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.693 0.307 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.691 0.309 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.690 0.310 0.000
G51.9 Disorder of facial nerve, unspecified
0.688 0.312 0.000
S61.1 Open wound of finger(s) with damage to nail
0.687 0.313 0.000
S65 Injury of blood vessels at wrist and hand level
0.687 0.313 0.000
I51.0 Cardiac septal defect, acquired
0.687 0.313 0.000
A07 Other protozoal intestinal diseases
0.686 0.314 0.000
A06 Amoebiasis
0.686 0.314 0.000
A05 Other bacterial foodborne intoxications
0.686 0.314 0.000
A03 Shigellosis
0.686 0.314 0.000
A01 Typhoid and paratyphoid fevers
0.686 0.314 0.000
A00 Cholera
0.686 0.314 0.000
E13 Other specified diabetes mellitus
0.686 0.314 0.000
G62.8 Other specified polyneuropathies
0.684 0.316 0.000
T19 Foreign body in genito-urinary tract
0.683 0.316 0.000
T15 Foreign body on external eye
0.683 0.316 0.000
T16 Foreign body in ear
0.683 0.316 0.000
X20-X29 Contact with venomous animals and plants
0.683 0.317 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.683 0.317 0.000
A08.4 Viral intestinal infection, unspecified
0.682 0.318 0.000
S60 Superficial injury of wrist and hand
0.681 0.319 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.681 0.319 0.000
N18.0 End-stage renal disease
0.681 0.319 0.000
D84 Other immunodeficiencies
0.680 0.319 0.000
D83 Common variable immunodeficiency
0.680 0.319 0.000
D82 Immunodeficiency associated with other major defects
0.680 0.319 0.000
D81 Combined immunodeficiencies
0.680 0.319 0.000
D80 Immunodeficiency with predominantly antibody defects
0.680 0.319 0.000
E55.9 Vitamin D deficiency, unspecified
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
Y00-Y09 Assault
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
D53.9 Nutritional anaemia, unspecified
0.678 0.322 0.000
I23 Certain current complications following acute myocardial infarction
0.678 0.322 0.000
I95.0 Idiopathic hypotension
0.678 0.322 0.000
T87 Complications peculiar to reattachment and amputation
0.677 0.322 0.000
H73 Other disorders of tympanic membrane
0.676 0.324 0.000
I33 Acute and subacute endocarditis
0.676 0.324 0.000
N18.5 Chronic kidney disease, stage 5
0.675 0.325 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.674 0.326 0.000
Q60-Q64 Congenital malformations of the urinary system
0.673 0.327 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.673 0.327 0.000
Q80-Q89 Other congenital malformations
0.673 0.327 0.000
M15-M19 Arthrosis
0.672 0.328 0.000
M14 Arthropathies in other diseases classified elsewhere
0.671 0.329 0.000
M12 Other specific arthropathies
0.671 0.329 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.671 0.329 0.000
M08 Juvenile arthritis
0.671 0.329 0.000
S62.51 Fracture of thumb (open)
0.671 0.329 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
N18.4 Chronic kidney disease, stage 4
0.669 0.331 0.000
A04.9 Bacterial intestinal infection, unspecified
0.668 0.331 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.668 0.331 0.000
A04.4 Other intestinal Escherichia coli infections
0.668 0.331 0.000
A04.3 Enterohaemorrhagic Escherichia coli infection
0.668 0.331 0.000
A04.2 Enteroinvasive Escherichia coli infection
0.668 0.331 0.000
A04.1 Enterotoxigenic Escherichia coli infection
0.668 0.331 0.000
A04.0 Enteropathogenic Escherichia coli infection
0.668 0.331 0.000
T81 Complications of procedures, not elsewhere classified
0.669 0.331 0.000
E40-E46 Malnutrition
0.668 0.332 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.667 0.333 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.333 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.667 0.333 0.000
G47.4 Narcolepsy and cataplexy
0.665 0.335 0.000
G47.2 Disorders of the sleep-wake schedule
0.665 0.335 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.665 0.335 0.000
D61.9 Aplastic anaemia, unspecified
0.664 0.336 0.000
H92.1 Otorrhoea
0.664 0.336 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.663 0.336 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.663 0.337 0.000
H70 Mastoiditis and related conditions
0.663 0.337 0.000
H69 Other disorders of Eustachian tube
0.663 0.337 0.000
H68 Eustachian salpingitis and obstruction
0.663 0.337 0.000
H67 Otitis media in diseases classified elsewhere
0.663 0.337 0.000
B18.2 Chronic viral hepatitis C
0.663 0.337 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.663 0.337 0.000
N00-N08 Glomerular diseases
0.661 0.339 0.000
M06.0 Seronegative rheumatoid arthritis
0.661 0.339 0.000
M67 Other disorders of synovium and tendon
0.661 0.339 0.000
M11 Other crystal arthropathies
0.660 0.340 0.000
H90.3 Sensorineural hearing loss, bilateral
0.660 0.340 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.659 0.341 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.658 0.341 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.658 0.341 0.000
M66 Spontaneous rupture of synovium and tendon
0.658 0.341 0.000
G51.8 Other disorders of facial nerve
0.658 0.342 0.000
G51.4 Facial myokymia
0.658 0.342 0.000
G51.3 Clonic hemifacial spasm
0.658 0.342 0.000
G51.2 Melkersson's syndrome
0.658 0.342 0.000
G51.1 Geniculate ganglionitis
0.658 0.342 0.000
M10.96 Gout, unspecified (Lower leg)
0.658 0.342 0.000
M85 Other disorders of bone density and structure
0.658 0.342 0.000
N10-N16 Renal tubulo-interstitial diseases
0.658 0.342 0.000
D50.9 Iron deficiency anaemia, unspecified
0.657 0.343 0.000
G95 Other diseases of spinal cord
0.657 0.343 0.000
L71 Rosacea
0.657 0.343 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.657 0.343 0.000
N60 Benign mammary dysplasia
0.657 0.343 0.000
B16 Acute hepatitis B
0.656 0.344 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.655 0.344 0.000
M34 Systemic sclerosis
0.655 0.344 0.000
M33 Dermatopolymyositis
0.655 0.344 0.000
M32 Systemic lupus erythematosus
0.655 0.344 0.000
M30 Polyarteritis nodosa and related conditions
0.655 0.344 0.000
W20-W49 Exposure to inanimate mechanical forces
0.654 0.345 0.000
B17 Other acute viral hepatitis
0.654 0.346 0.000
I24.8 Other forms of acute ischaemic heart disease
0.653 0.347 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.653 0.347 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.653 0.347 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.653 0.347 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.653 0.347 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.653 0.347 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.653 0.347 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.653 0.347 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.652 0.348 0.000
T17.5 Foreign body in bronchus
0.652 0.348 0.000
T17.4 Foreign body in trachea
0.652 0.348 0.000
T17.3 Foreign body in larynx
0.652 0.348 0.000
T17.1 Foreign body in nostril
0.652 0.348 0.000
T17.0 Foreign body in nasal sinus
0.652 0.348 0.000
E23 Hypofunction and other disorders of pituitary gland
0.652 0.348 0.000
A41 Other septicaemia
0.652 0.348 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.651 0.349 0.000
V80-V89 Other land transport accidents
0.651 0.349 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.651 0.349 0.000
D86.3 Sarcoidosis of skin
0.650 0.350 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.650 0.350 0.000
N32 Other disorders of bladder
0.650 0.350 0.000
L54 Erythema in diseases classified elsewhere
0.649 0.350 0.000
L51 Erythema multiforme
0.649 0.350 0.000
L52 Erythema nodosum
0.649 0.350 0.000
I52 Other heart disorders in diseases classified elsewhere
0.648 0.352 0.000
I48 Atrial fibrillation and flutter
0.648 0.352 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.648 0.352 0.000
I41 Myocarditis in diseases classified elsewhere
0.648 0.352 0.000
I40 Acute myocarditis
0.648 0.352 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.648 0.352 0.000
I37 Pulmonary valve disorders
0.648 0.352 0.000
I36 Nonrheumatic tricuspid valve disorders
0.648 0.352 0.000
I32 Pericarditis in diseases classified elsewhere
0.648 0.352 0.000
N17.8 Other acute renal failure
0.648 0.352 0.000
N17.2 Acute renal failure with medullary necrosis
0.648 0.352 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.648 0.352 0.000
N17.0 Acute renal failure with tubular necrosis
0.648 0.352 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.647 0.353 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.647 0.353 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.646 0.353 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.646 0.354 0.000
H65 Nonsuppurative otitis media
0.646 0.354 0.000
L03.9 Cellulitis, unspecified
0.646 0.354 0.000
M21 Other acquired deformities of limbs
0.646 0.354 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.644 0.356 0.000
G57.5 Tarsal tunnel syndrome
0.644 0.356 0.000
G57.4 Lesion of medial popliteal nerve
0.644 0.356 0.000
G57.3 Lesion of lateral popliteal nerve
0.644 0.356 0.000
G57.2 Lesion of femoral nerve
0.644 0.356 0.000
G57.1 Meralgia paraesthetica
0.644 0.356 0.000
G57.0 Lesion of sciatic nerve
0.644 0.356 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.644 0.356 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.644 0.356 0.000
N37 Urethral disorders in diseases classified elsewhere
0.644 0.356 0.000
N33 Bladder disorders in diseases classified elsewhere
0.644 0.356 0.000
M10.4 Other secondary gout
0.642 0.358 0.000
M10.3 Gout due to impairment of renal function
0.642 0.358 0.000
M10.2 Drug-induced gout
0.642 0.358 0.000
M10.1 Lead-induced gout
0.642 0.358 0.000
M10.0 Idiopathic gout
0.642 0.358 0.000
H74.4 Polyp of middle ear
0.642 0.358 0.000
I51.6 Cardiovascular disease, unspecified
0.641 0.359 0.000
I51.5 Myocardial degeneration
0.641 0.359 0.000
I51.4 Myocarditis, unspecified
0.641 0.359 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.641 0.359 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.641 0.359 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.641 0.359 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.640 0.359 0.000
G56.8 Other mononeuropathies of upper limb
0.640 0.359 0.000
G56.4 Causalgia
0.640 0.359 0.000
G56.3 Lesion of radial nerve
0.640 0.359 0.000
G56.1 Other lesions of median nerve
0.640 0.359 0.000
S62.2 Fracture of first metacarpal bone
0.640 0.360 0.000
B35 Dermatophytosis
0.640 0.360 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.639 0.361 0.000
I51.7 Cardiomegaly
0.639 0.361 0.000
M83 Adult osteomalacia
0.638 0.362 0.000
M82 Osteoporosis in diseases classified elsewhere
0.638 0.362 0.000
I62 Other nontraumatic intracranial haemorrhage
0.637 0.363 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.637 0.363 0.000
I20.8 Other forms of angina pectoris
0.637 0.363 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.636 0.364 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.636 0.364 0.000
G71 Primary disorders of muscles
0.636 0.364 0.000
N34 Urethritis and urethral syndrome
0.636 0.364 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.636 0.364 0.000
E63 Other nutritional deficiencies
0.636 0.364 0.000
E56 Other vitamin deficiencies
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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