TreeWAS – Variant ID: rs11680788

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C79 Secondary malignant neoplasm of other sites	0.000	0.942	0.058
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.945	0.055
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.945	0.055
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.945	0.055
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.948	0.052
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.949	0.051
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.949	0.051
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.951	0.049
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.951	0.049
C80 Malignant neoplasm without specification of site	0.000	0.954	0.046
C79.6 Secondary malignant neoplasm of ovary	0.000	0.956	0.044
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.958	0.042
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.958	0.042
C80.9 Malignant neoplasm, unspecified	0.000	0.959	0.041
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.960	0.040
C79.2 Secondary malignant neoplasm of skin	0.000	0.961	0.039
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.962	0.038
C78.2 Secondary malignant neoplasm of pleura	0.000	0.962	0.038
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.962	0.038
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.963	0.037
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.963	0.037
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.963	0.037
Z87 Personal history of other diseases and conditions	0.000	0.963	0.037
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.964	0.036
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.964	0.036
C78.0 Secondary malignant neoplasm of lung	0.000	0.965	0.035
Z87.0 Personal history of diseases of the respiratory system	0.000	0.965	0.035
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.966	0.034
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.967	0.033
C78.7 Secondary malignant neoplasm of liver	0.000	0.967	0.033
Z87.8 Personal history of other specified conditions	0.000	0.970	0.030
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.972	0.028
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.973	0.026
C76.7 Other ill-defined sites	0.000	0.973	0.026
C76.5 Lower limb	0.000	0.973	0.026
C76.4 Upper limb	0.000	0.973	0.026
C76.3 Pelvis	0.000	0.973	0.026
C76.2 Abdomen	0.000	0.973	0.026
C76.1 Thorax	0.000	0.973	0.026
C76.0 Head, face and neck	0.000	0.973	0.026
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.973	0.026
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.980	0.020
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.982	0.017
K83.1 Obstruction of bile duct	0.000	0.986	0.014
K83 Other diseases of biliary tract	0.000	0.989	0.011
K83.0 Cholangitis	0.000	0.990	0.010
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.991	0.009
S82.60 Fracture of lateral malleolus (closed)	0.000	0.991	0.009
R39.1 Other difficulties with micturition	0.000	0.991	0.009
K83.8 Other specified diseases of biliary tract	0.000	0.992	0.008
S82.8 Fractures of other parts of lower leg	0.000	0.992	0.008
S82.6 Fracture of lateral malleolus	0.000	0.992	0.008
S82 Fracture of lower leg, including ankle	0.000	0.992	0.008
K83.9 Disease of biliary tract, unspecified	0.000	0.992	0.008
K83.5 Biliary cyst	0.000	0.992	0.008
K83.4 Spasm of sphincter of Oddi	0.000	0.992	0.008
K83.3 Fistula of bile duct	0.000	0.992	0.008
K83.2 Perforation of bile duct	0.000	0.992	0.008
S82.30 Fracture of lower end of tibia (closed)	0.000	0.992	0.008
S82.3 Fracture of lower end of tibia	0.000	0.993	0.007
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.993	0.007
S82.5 Fracture of medial malleolus	0.000	0.993	0.007
D68.9 Coagulation defect, unspecified	0.006	0.994	0.000
S82.1 Fracture of upper end of tibia	0.000	0.994	0.006
S82.86 Maisonneuve's fracture	0.000	0.994	0.006
S82.81 Fractures of other parts of lower leg (open)	0.000	0.994	0.006
S82.61 Fracture of lateral malleolus (open)	0.000	0.994	0.006
S82.0 Fracture of patella	0.000	0.994	0.006
C77.9 Lymph node, unspecified	0.000	0.994	0.006
S82.9 Fracture of lower leg, part unspecified	0.000	0.994	0.006
S82.7 Multiple fractures of lower leg	0.000	0.994	0.006
S82.50 Fracture of medial malleolus (closed)	0.000	0.994	0.006
C77.8 Lymph nodes of multiple regions	0.000	0.994	0.005
C77.0 Lymph nodes of head, face and neck	0.000	0.995	0.005
S82.00 Fracture of patella (closed)	0.000	0.995	0.005
H92.1 Otorrhoea	0.005	0.995	0.000
N28.1 Cyst of kidney, acquired	0.000	0.995	0.005
H02.8 Other specified disorders of eyelid	0.005	0.995	0.000
S82.10 Fracture of upper end of tibia (closed)	0.000	0.995	0.005
S82.51 Fracture of medial malleolus (open)	0.000	0.995	0.005
N28.8 Other specified disorders of kidney and ureter	0.000	0.995	0.005
S82.4 Fracture of fibula alone	0.000	0.995	0.005
S82.31 Fracture of lower end of tibia (open)	0.000	0.995	0.005
S82.11 Fracture of upper end of tibia (open)	0.000	0.995	0.005
T51.0 Ethanol	0.005	0.995	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.995	0.005
C77.1 Intrathoracic lymph nodes	0.000	0.995	0.005
S82.71 Multiple fractures of lower leg (open)	0.000	0.995	0.004
S82.70 Multiple fractures of lower leg (closed)	0.000	0.995	0.004
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.995	0.004
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.995	0.004
S82.2 Fracture of shaft of tibia	0.000	0.995	0.004
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.996	0.004
D25.1 Intramural leiomyoma of uterus	0.000	0.996	0.004
D68 Other coagulation defects	0.004	0.996	0.000
S82.01 Fracture of patella (open)	0.000	0.996	0.004
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
H61 Other disorders of external ear	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.004	0.996	0.000
S82.41 Fracture of fibula alone (open)	0.000	0.996	0.004
C77.4 Inguinal and lower limb lymph nodes	0.000	0.996	0.004
N20.0 Calculus of kidney	0.000	0.996	0.004
H61.2 Impacted cerumen	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.004	0.996	0.000
B02.2 Zoster with other nervous system involvement	0.004	0.996	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.996	0.004
B02.3 Zoster ocular disease	0.004	0.996	0.000
B02 Zoster [herpes zoster]	0.004	0.996	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.996	0.003
B02.9 Zoster without complication	0.003	0.996	0.000
C56 Malignant neoplasm of ovary	0.000	0.997	0.003
H60 Otitis externa	0.003	0.997	0.000
H60-H62 Diseases of external ear	0.003	0.997	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.997	0.003
H02 Other disorders of eyelid	0.003	0.997	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.003	0.997	0.000
T51 Toxic effect of alcohol	0.003	0.997	0.000
N30.8 Other cystitis	0.000	0.997	0.003
H83.0 Labyrinthitis	0.003	0.997	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
H02.3 Blepharochalasis	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
K02.9 Dental caries, unspecified	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
H02.1 Ectropion of eyelid	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
T51.9 Alcohol, unspecified	0.003	0.997	0.000
H02.5 Other disorders affecting eyelid function	0.003	0.997	0.000
H92.2 Otorrhagia	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.000	0.997	0.003
S82.40 Fracture of fibula alone (closed)	0.000	0.997	0.003
D68.0 Von Willebrand's disease	0.003	0.997	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.997	0.003
H92.0 Otalgia	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
H83 Other diseases of inner ear	0.003	0.997	0.000
B02.8 Zoster with other complications	0.003	0.997	0.000
B02.7 Disseminated zoster	0.003	0.997	0.000
B02.1 Zoster meningitis	0.003	0.997	0.000
B02.0 Zoster encephalitis	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
H02.2 Lagophthalmos	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
H60.5 Acute otitis externa, non-infective	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.003	0.997	0.000
H60.0 Abscess of external ear	0.003	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.997	0.003
H02.7 Other degenerative disorders of eyelid and periocular area	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.000	0.997	0.003
H02.0 Entropion and trichiasis of eyelid	0.003	0.997	0.000
T51.8 Other alcohols	0.003	0.997	0.000
T51.3 Fusel oil	0.003	0.997	0.000
T51.2 2-Propanol	0.003	0.997	0.000
T51.1 Methanol	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.003	0.997	0.000
H90-H95 Other disorders of ear	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.000	0.997	0.003
R23.3 Spontaneous ecchymoses	0.002	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.002	0.997	0.000
H02.6 Xanthelasma of eyelid	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.002	0.998	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
M20.2 Hallux rigidus	0.000	0.998	0.002
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
X62.9 Unspecified place	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.000	0.998	0.002
S87 Crushing injury of lower leg	0.000	0.998	0.002
S85 Injury of blood vessels at lower leg level	0.000	0.998	0.002
S84 Injury of nerves at lower leg level	0.000	0.998	0.002
K13.7 Other and unspecified lesions of oral mucosa	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
H02.4 Ptosis of eyelid	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
T42.4 Benzodiazepines	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
H91 Other hearing loss	0.002	0.998	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
L30.9 Dermatitis, unspecified	0.000	0.998	0.002
H80 Otosclerosis	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
E87.7 Fluid overload	0.002	0.998	0.000
K13.0 Diseases of lips	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
R23.1 Pallor	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
Z51.5 Palliative care	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.998	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.998	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.998	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.998	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.998	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.998	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.998	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.998	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.998	0.002
S85.5 Injury of popliteal vein	0.000	0.998	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.998	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.998	0.002
S85.2 Injury of peroneal artery	0.000	0.998	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.998	0.002
S85.0 Injury of popliteal artery	0.000	0.998	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.998	0.002
S87.0 Crushing injury of knee	0.000	0.998	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.998	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.998	0.002
S88.0 Traumatic amputation at knee level	0.000	0.998	0.002
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.000	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
S52.50 Fracture of lower end of radius (closed)	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
R23.0 Cyanosis	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.998	0.000
D84.8 Other specified immunodeficiencies	0.001	0.998	0.000
D84.1 Defects in the complement system	0.001	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.998	0.000
H80.8 Other otosclerosis	0.001	0.998	0.000
H80.2 Cochlear otosclerosis	0.001	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.998	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.000	0.998	0.001
S89.1 Other specified injuries of lower leg	0.000	0.998	0.001
S89.0 Multiple injuries of lower leg	0.000	0.998	0.001
T36.9 Systemic antibiotic, unspecified	0.001	0.998	0.000
T36.8 Other systemic antibiotics	0.001	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
T36.6 Rifamycins	0.001	0.998	0.000
T36.5 Aminoglycosides	0.001	0.998	0.000
T36.4 Tetracyclines	0.001	0.998	0.000
T36.3 Macrolides	0.001	0.998	0.000
T36.2 Chloramphenicol group	0.001	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.998	0.000
T36.0 Penicillins	0.001	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.1 Calcium-channel blockers	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.4 Other laxatives	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
T47.2 Stimulant laxatives	0.001	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
X63.0 Home	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
N25-N29 Other disorders of kidney and ureter	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.998	0.000
H93.9 Disorder of ear, unspecified	0.001	0.998	0.000
H93.8 Other specified disorders of ear	0.001	0.998	0.000
H93.3 Disorders of acoustic nerve	0.001	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.998	0.000
S86.0 Injury of Achilles tendon	0.000	0.998	0.001
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.001
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations