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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116839510
log Bayes Factor = 15.1511
Chromosome 2   position 192,466,150  (GRCh37) Explore rs116839510 on Ensembl!
Variant rs116839510 is part of Cluster X0154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
T81 Complications of procedures, not elsewhere classified
0.990 0.010 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.987 0.013 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.982 0.018 0.000
M80-M85 Disorders of bone density and structure
0.978 0.022 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.977 0.023 0.000
N93 Other abnormal uterine and vaginal bleeding
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.971 0.029 0.000
Chapter XXI Factors influencing health status and contact with health services
0.971 0.029 0.000
N30-N39 Other diseases of urinary system
0.968 0.032 0.000
M20-M25 Other joint disorders
0.963 0.037 0.000
N17-N19 Renal failure
0.962 0.038 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.957 0.043 0.000
N00-N08 Glomerular diseases
0.954 0.046 0.000
S20-S29 Injuries to the thorax
0.950 0.050 0.000
N18 Chronic renal failure
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.949 0.051 0.000
Chapter I Certain infectious and parasitic diseases
0.948 0.052 0.000
M81 Osteoporosis without pathological fracture
0.944 0.056 0.000
M25 Other joint disorders, not elsewhere classified
0.943 0.057 0.000
M54 Dorsalgia
0.941 0.059 0.000
M65-M68 Disorders of synovium and tendon
0.939 0.061 0.000
N87 Dysplasia of cervix uteri
0.939 0.061 0.000
N35 Urethral stricture
0.938 0.062 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.936 0.064 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.935 0.065 0.000
O60-O75 Complications of labour and delivery
0.933 0.067 0.000
Chapter II Neoplasms
0.931 0.069 0.000
B95-B98 Bacterial, viral and other infectious agents
0.918 0.082 0.000
M25.4 Effusion of joint
0.917 0.083 0.000
D00-D09 In situ neoplasms
0.911 0.089 0.000
M65 Synovitis and tenosynovitis
0.910 0.090 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.910 0.090 0.000
M15-M19 Arthrosis
0.907 0.093 0.000
M05-M14 Inflammatory polyarthropathies
0.907 0.093 0.000
M81.9 Osteoporosis, unspecified
0.907 0.093 0.000
Z43 Attention to artificial openings
0.906 0.094 0.000
N18.3 Chronic kidney disease, stage 3
0.904 0.096 0.000
M25.46 Effusion of joint (Lower leg)
0.903 0.097 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.903 0.097 0.000
N35.9 Urethral stricture, unspecified
0.900 0.100 0.000
T86 Failure and rejection of transplanted organs and tissues
0.885 0.115 0.000
T79-T79 Certain early complications of trauma
0.878 0.122 0.000
C15-C26 Malignant neoplasms of digestive organs
0.877 0.123 0.000
M54.1 Radiculopathy
0.875 0.125 0.000
M84 Disorders of continuity of bone
0.871 0.129 0.000
N03 Chronic nephritic syndrome
0.869 0.131 0.000
Chapter VII Diseases of the eye and adnexa
0.867 0.133 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.866 0.134 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.864 0.136 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.864 0.136 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.864 0.136 0.000
N89 Other noninflammatory disorders of vagina
0.863 0.137 0.000
S70-S79 Injuries to the hip and thigh
0.862 0.138 0.000
Z80 Family history of malignant neoplasm
0.859 0.141 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.859 0.141 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.858 0.142 0.000
Chapter V Mental and behavioural disorders
0.857 0.143 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.855 0.145 0.000
O47 False labour
0.855 0.145 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.854 0.146 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.851 0.149 0.000
N84 Polyp of female genital tract
0.851 0.149 0.000
N95 Menopausal and other perimenopausal disorders
0.850 0.150 0.000
O48 Prolonged pregnancy
0.846 0.153 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.846 0.154 0.000
N18.9 Chronic renal failure, unspecified
0.841 0.159 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.841 0.159 0.000
Z92 Personal history of medical treatment
0.841 0.159 0.000
Chapter VIII Diseases of the ear and mastoid process
0.840 0.160 0.000
N99-N99 Other disorders of the genitourinary system
0.838 0.162 0.000
N87.1 Moderate cervical dysplasia
0.837 0.163 0.000
N87.0 Mild cervical dysplasia
0.837 0.163 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.836 0.164 0.000
M21 Other acquired deformities of limbs
0.835 0.165 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.834 0.166 0.000
Z46 Fitting and adjustment of other devices
0.834 0.166 0.000
N93.0 Postcoital and contact bleeding
0.833 0.167 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.833 0.167 0.000
S00-S09 Injuries to the head
0.833 0.167 0.000
O00-O08 Pregnancy with abortive outcome
0.829 0.171 0.000
M06 Other rheumatoid arthritis
0.825 0.175 0.000
M65.3 Trigger finger
0.825 0.175 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.824 0.176 0.000
N18.4 Chronic kidney disease, stage 4
0.823 0.177 0.000
N95.0 Postmenopausal bleeding
0.821 0.179 0.000
Z49 Care involving dialysis
0.820 0.180 0.000
M86-M90 Other osteopathies
0.820 0.180 0.000
N02 Recurrent and persistent haematuria
0.820 0.180 0.000
M17 Gonarthrosis [arthrosis of knee]
0.820 0.180 0.000
M54.5 Low back pain
0.818 0.182 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.817 0.183 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.816 0.184 0.000
S22.4 Multiple fractures of ribs
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.814 0.186 0.000
N39 Other disorders of urinary system
0.813 0.187 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.812 0.188 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.811 0.189 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.810 0.190 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.810 0.190 0.000
D06 Carcinoma in situ of cervix uteri
0.809 0.191 0.000
N03.9 Unspecified
0.809 0.191 0.000
D05 Carcinoma in situ of breast
0.808 0.192 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.806 0.194 0.000
S40-S49 Injuries to the shoulder and upper arm
0.805 0.195 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.803 0.197 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.802 0.198 0.000
O43 Placental disorders
0.802 0.198 0.000
Z40 Prophylactic surgery
0.793 0.207 0.000
E20-E35 Disorders of other endocrine glands
0.792 0.208 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.792 0.208 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.792 0.208 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.792 0.208 0.000
O36 Maternal care for other known or suspected foetal problems
0.791 0.209 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.791 0.209 0.000
M54.3 Sciatica
0.790 0.210 0.000
Z93 Artificial opening status
0.790 0.210 0.000
O72 Postpartum haemorrhage
0.790 0.210 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.789 0.211 0.000
S22.3 Fracture of rib
0.789 0.211 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.789 0.211 0.000
Z80.3 Family history of malignant neoplasm of breast
0.789 0.211 0.000
H10-H13 Disorders of conjunctiva
0.788 0.212 0.000
Z43.3 Attention to colostomy
0.787 0.213 0.000
M54.16 Radiculopathy (Lumbar region)
0.787 0.213 0.000
N39.0 Urinary tract infection, site not specified
0.787 0.213 0.000
Chapter IX Diseases of the circulatory system
0.786 0.214 0.000
M10 Gout
0.786 0.214 0.000
N35.8 Other urethral stricture
0.785 0.215 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.784 0.216 0.000
C15 Malignant neoplasm of oesophagus
0.783 0.217 0.000
M54.4 Lumbago with sciatica
0.781 0.219 0.000
T82.1 Mechanical complication of cardiac electronic device
0.778 0.222 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.778 0.222 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.778 0.222 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.774 0.226 0.000
F30-F39 Mood [affective] disorders
0.774 0.226 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.773 0.227 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.771 0.229 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.770 0.230 0.000
M81.4 Drug-induced osteoporosis
0.767 0.233 0.000
H25-H28 Disorders of lens
0.767 0.233 0.000
Z83 Family history of other specific disorders
0.767 0.233 0.000
W00-W19 Falls
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.766 0.234 0.000
M25.7 Osteophyte
0.765 0.235 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
M65.34 Trigger finger-Hand
0.764 0.236 0.000
D03 Melanoma in situ
0.763 0.237 0.000
T51 Toxic effect of alcohol
0.762 0.238 0.000
Z43.1 Attention to gastrostomy
0.760 0.240 0.000
S22.2 Fracture of sternum
0.760 0.240 0.000
T39.1 4-Aminophenol derivatives
0.759 0.241 0.000
A30-A49 Other bacterial diseases
0.759 0.241 0.000
N34 Urethritis and urethral syndrome
0.757 0.243 0.000
Z42 Follow-up care involving plastic surgery
0.756 0.244 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.755 0.245 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.754 0.245 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.754 0.246 0.000
M53 Other dorsopathies, not elsewhere classified
0.754 0.246 0.000
Z44 Fitting and adjustment of external prosthetic device
0.753 0.247 0.000
Chapter X Diseases of the respiratory system
0.753 0.247 0.000
O41 Other disorders of amniotic fluid and membranes
0.752 0.247 0.000
E00-E07 Disorders of thyroid gland
0.752 0.248 0.000
N10-N16 Renal tubulo-interstitial diseases
0.751 0.249 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.751 0.249 0.000
O04 Medical abortion
0.750 0.250 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.750 0.250 0.000
O30 Multiple gestation
0.749 0.251 0.000
H80-H83 Diseases of inner ear
0.748 0.252 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.748 0.252 0.000
Z46.8 Fitting and adjustment of other specified devices
0.747 0.253 0.000
S22.40 Multiple fractures of ribs (closed)
0.747 0.253 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.746 0.254 0.000
S10-S19 Injuries to the neck
0.744 0.256 0.000
N82 Fistulae involving female genital tract
0.744 0.256 0.000
M91-M94 Chondropathies
0.742 0.257 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.742 0.258 0.000
M54.59 Low back pain (Site unspecified)
0.742 0.258 0.000
Z43.2 Attention to ileostomy
0.741 0.259 0.000
O61 Failed induction of labour
0.741 0.259 0.000
M17.1 Other primary gonarthrosis
0.741 0.259 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.741 0.259 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.740 0.260 0.000
M18 Arthrosis of first carpometacarpal joint
0.739 0.260 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.738 0.262 0.000
M81.98 Osteoporosis, unspecified (Other)
0.737 0.263 0.000
D04 Carcinoma in situ of skin
0.736 0.264 0.000
N88 Other noninflammatory disorders of cervix uteri
0.736 0.264 0.000
D06.9 Cervix, unspecified
0.736 0.264 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.736 0.264 0.000
M40-M43 Deforming dorsopathies
0.734 0.266 0.000
S09 Other and unspecified injuries of head
0.734 0.266 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.734 0.266 0.000
M17.9 Gonarthrosis, unspecified
0.733 0.267 0.000
S72 Fracture of femur
0.733 0.267 0.000
M25.5 Pain in joint
0.733 0.267 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.732 0.268 0.000
M70-M79 Other soft tissue disorders
0.732 0.268 0.000
Z98 Other postsurgical states
0.731 0.269 0.000
F31 Bipolar affective disorder
0.731 0.269 0.000
I10-I15 Hypertensive diseases
0.730 0.270 0.000
H43-H45 Disorders of vitreous body and globe
0.730 0.270 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.729 0.271 0.000
Z43.8 Attention to other artificial openings
0.729 0.271 0.000
Chapter XXII Codes for special purposes
0.729 0.271 0.000
T81.9 Unspecified complication of procedure
0.729 0.271 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.729 0.271 0.000
T90 Sequelae of injuries of head
0.728 0.271 0.000
M06.9 Rheumatoid arthritis, unspecified
0.728 0.272 0.000
S60-S69 Injuries to the wrist and hand
0.727 0.273 0.000
O44 Placenta praevia
0.727 0.273 0.000
J20-J22 Other acute lower respiratory infections
0.727 0.273 0.000
T43.2 Other and unspecified antidepressants
0.726 0.274 0.000
O42 Premature rupture of membranes
0.726 0.274 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.724 0.276 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.724 0.276 0.000
N02.9 Unspecified
0.723 0.277 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.722 0.278 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.721 0.279 0.000
Z48 Other surgical follow-up care
0.721 0.279 0.000
M00-M03 Infectious arthropathies
0.721 0.279 0.000
O40 Polyhydramnios
0.721 0.279 0.000
N18.5 Chronic kidney disease, stage 5
0.721 0.279 0.000
M51 Other intervertebral disk disorders
0.721 0.279 0.000
B25-B34 Other viral diseases
0.721 0.279 0.000
V10-V19 Pedal cyclist injured in transport accident
0.719 0.281 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.719 0.281 0.000
H25 Senile cataract
0.719 0.281 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.717 0.283 0.000
O62 Abnormalities of forces of labour
0.717 0.283 0.000
N04 Nephrotic syndrome
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
O72.1 Other immediate postpartum haemorrhage
0.715 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.714 0.285 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.714 0.286 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.711 0.289 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.710 0.290 0.000
I12 Hypertensive renal disease
0.710 0.290 0.000
M50 Cervical disk disorders
0.710 0.290 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.710 0.290 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.710 0.290 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.710 0.290 0.000
Chapter VI Diseases of the nervous system
0.709 0.291 0.000
C15.5 Lower third of oesophagus
0.709 0.291 0.000
Z49.0 Preparatory care for dialysis
0.709 0.291 0.000
C20 Malignant neoplasm of rectum
0.708 0.292 0.000
N98 Complications associated with artificial fertilisation
0.708 0.292 0.000
N91 Absent, scanty and rare menstruation
0.708 0.292 0.000
N96 Habitual aborter
0.708 0.292 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.708 0.292 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.708 0.292 0.000
H11 Other disorders of conjunctiva
0.707 0.293 0.000
J22 Unspecified acute lower respiratory infection
0.707 0.293 0.000
Z92.8 Personal history of other medical treatment
0.707 0.293 0.000
N05 Unspecified nephritic syndrome
0.706 0.294 0.000
E22 Hyperfunction of pituitary gland
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.704 0.296 0.000
O45 Premature separation of placenta [abruptio placentae]
0.704 0.296 0.000
O33 Maternal care for known or suspected disproportion
0.704 0.296 0.000
O31 Complications specific to multiple gestation
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
T82.3 Mechanical complication of other vascular grafts
0.703 0.297 0.000
S22.30 Fracture of rib (closed)
0.702 0.298 0.000
Y95 Nosocomial condition
0.702 0.298 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.701 0.299 0.000
M83 Adult osteomalacia
0.701 0.299 0.000
M82 Osteoporosis in diseases classified elsewhere
0.701 0.299 0.000
M85 Other disorders of bone density and structure
0.701 0.299 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.701 0.299 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.700 0.300 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.700 0.300 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.700 0.300 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.700 0.300 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.700 0.300 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.700 0.300 0.000
S27 Injury of other and unspecified intrathoracic organs
0.700 0.300 0.000
Z92.3 Personal history of irradiation
0.700 0.300 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.700 0.300 0.000
Z97 Presence of other devices
0.700 0.300 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.699 0.301 0.000
N60-N64 Disorders of breast
0.699 0.301 0.000
M10.9 Gout, unspecified
0.699 0.301 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.698 0.302 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.697 0.303 0.000
M24 Other specific joint derangements
0.697 0.303 0.000
N97 Female infertility
0.697 0.303 0.000
Z52 Donors of organs and tissues
0.696 0.304 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.696 0.304 0.000
W20-W49 Exposure to inanimate mechanical forces
0.695 0.304 0.000
T51.0 Ethanol
0.695 0.305 0.000
T45.0 Antiallergic and antiemetic drugs
0.695 0.305 0.000
N84.0 Polyp of corpus uteri
0.695 0.305 0.000
C18 Malignant neoplasm of colon
0.694 0.306 0.000
N37 Urethral disorders in diseases classified elsewhere
0.694 0.306 0.000
N33 Bladder disorders in diseases classified elsewhere
0.694 0.306 0.000
O04.9 Complete or unspecified, without complication
0.694 0.306 0.000
H25.8 Other senile cataract
0.694 0.306 0.000
Z54 Convalescence
0.693 0.307 0.000
N20-N23 Urolithiasis
0.693 0.307 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.692 0.308 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.691 0.309 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.309 0.000
M34 Systemic sclerosis
0.690 0.309 0.000
M33 Dermatopolymyositis
0.690 0.309 0.000
M32 Systemic lupus erythematosus
0.690 0.309 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.309 0.000
D05.1 Intraductal carcinoma in situ
0.690 0.310 0.000
N36 Other disorders of urethra
0.690 0.310 0.000
N84.2 Polyp of vagina
0.689 0.311 0.000
S20 Superficial injury of thorax
0.688 0.311 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.688 0.312 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.688 0.312 0.000
I12.0 Hypertensive renal disease with renal failure
0.686 0.314 0.000
M06.0 Seronegative rheumatoid arthritis
0.685 0.315 0.000
O23 Infections of genito-urinary tract in pregnancy
0.685 0.315 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.684 0.316 0.000
N06 Isolated proteinuria with specified morphological lesion
0.684 0.316 0.000
N01 Rapidly progressive nephritic syndrome
0.684 0.316 0.000
N00 Acute nephritic syndrome
0.684 0.316 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.683 0.317 0.000
Z84 Family history of other conditions
0.682 0.318 0.000
M19 Other arthrosis
0.681 0.319 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.681 0.319 0.000
S29 Other and unspecified injuries of thorax
0.681 0.319 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.681 0.319 0.000
S26 Injury of heart
0.681 0.319 0.000
S25 Injury of blood vessels of thorax
0.681 0.319 0.000
S24 Injury of nerves and spinal cord at thorax level
0.681 0.319 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.681 0.319 0.000
S21 Open wound of thorax
0.681 0.319 0.000
N18.8 Other chronic renal failure
0.680 0.320 0.000
N18.1 Chronic kidney disease, stage 1
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
Y00-Y09 Assault
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
B99-B99 Other infectious diseases
0.680 0.320 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.680 0.320 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.680 0.320 0.000
B65-B83 Helminthiases
0.680 0.320 0.000
B50-B64 Protozoal diseases
0.680 0.320 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.680 0.320 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.680 0.320 0.000
A75-A79 Rickettsioses
0.680 0.320 0.000
A70-A74 Other diseases caused by chlamydiae
0.680 0.320 0.000
A65-A69 Other spirochaetal diseases
0.680 0.320 0.000
A20-A28 Certain zoonotic bacterial diseases
0.680 0.320 0.000
A15-A19 Tuberculosis
0.680 0.320 0.000
M11 Other crystal arthropathies
0.679 0.321 0.000
B35-B49 Mycoses
0.679 0.321 0.000
O47.9 False labour, unspecified
0.678 0.322 0.000
M54.2 Cervicalgia
0.678 0.322 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.678 0.322 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.677 0.323 0.000
C01 Malignant neoplasm of base of tongue
0.677 0.323 0.000
V80-V89 Other land transport accidents
0.677 0.323 0.000
M21.3 Wrist or foot drop (acquired)
0.677 0.323 0.000
M81.8 Other osteoporosis
0.677 0.323 0.000
M81.6 Localised osteoporosis [Lequesne]
0.677 0.323 0.000
M81.5 Idiopathic osteoporosis
0.677 0.323 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.677 0.323 0.000
M81.2 Osteoporosis of disuse
0.677 0.323 0.000
M81.1 Postoophorectomy osteoporosis
0.677 0.323 0.000
M81.0 Postmenopausal osteoporosis
0.677 0.323 0.000
Z93.2 Ileostomy status
0.677 0.323 0.000
C21 Malignant neoplasm of anus and anal canal
0.676 0.324 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.676 0.324 0.000
M25.9 Joint disorder, unspecified
0.676 0.324 0.000
M25.3 Other instability of joint
0.676 0.324 0.000
M25.2 Flail joint
0.676 0.324 0.000
M25.1 Fistula of joint
0.676 0.324 0.000
M25.0 Haemarthrosis
0.676 0.324 0.000
H40-H42 Glaucoma
0.676 0.324 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.675 0.325 0.000
M54.8 Other dorsalgia
0.674 0.325 0.000
M54.0 Panniculitis affecting regions of neck and back
0.674 0.325 0.000
S71 Open wound of hip and thigh
0.674 0.326 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.674 0.326 0.000
M66 Spontaneous rupture of synovium and tendon
0.674 0.326 0.000
F80-F89 Disorders of psychological development
0.673 0.326 0.000
O43.1 Malformation of placenta
0.673 0.327 0.000
O70 Perineal laceration during delivery
0.672 0.328 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.672 0.328 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.672 0.328 0.000
N35.0 Posttraumatic urethral stricture
0.672 0.328 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.672 0.328 0.000
M25.8 Other specified joint disorders
0.672 0.328 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.672 0.328 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.671 0.329 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.671 0.329 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.671 0.329 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.671 0.329 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.671 0.329 0.000
N39.9 Disorder of urinary system, unspecified
0.670 0.330 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.670 0.330 0.000
Z83.5 Family history of eye and ear disorders
0.670 0.330 0.000
M54.6 Pain in thoracic spine
0.670 0.330 0.000
O74 Complications of anaesthesia during labour and delivery
0.669 0.331 0.000
O73 Retained placenta and membranes, without haemorrhage
0.669 0.331 0.000
O71 Other obstetric trauma
0.669 0.331 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.669 0.331 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.669 0.331 0.000
O60 Preterm delivery
0.669 0.331 0.000
M22 Disorders of patella
0.668 0.332 0.000
T86.1 Kidney transplant failure and rejection
0.668 0.332 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.667 0.332 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.667 0.332 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.667 0.333 0.000
Z22 Carrier of infectious disease
0.666 0.334 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.666 0.334 0.000
Z37 Outcome of delivery
0.666 0.334 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.666 0.334 0.000
M84.0 Malunion of fracture
0.666 0.334 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.666 0.334 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.665 0.335 0.000
M23 Internal derangement of knee
0.665 0.335 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.665 0.335 0.000
S09.9 Unspecified injury of head
0.663 0.337 0.000
O47.0 False labour before 37 completed weeks of gestation
0.663 0.337 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.663 0.337 0.000
A80-A89 Viral infections of the central nervous system
0.663 0.337 0.000
M87 Osteonecrosis
0.663 0.337 0.000
O36.9 Maternal care for foetal problem, unspecified
0.662 0.337 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.662 0.338 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.661 0.339 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.660 0.340 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.660 0.340 0.000
H83 Other diseases of inner ear
0.659 0.341 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.659 0.341 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.659 0.341 0.000
I60-I69 Cerebrovascular diseases
0.659 0.341 0.000
T79.7 Traumatic subcutaneous emphysema
0.658 0.341 0.000
N18.0 End-stage renal disease
0.658 0.341 0.000
M25.49 Effusion of joint (Site unspecified)
0.657 0.343 0.000
M25.48 Effusion of joint (Other)
0.657 0.343 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.657 0.343 0.000
M25.44 Effusion of joint (Hand)
0.657 0.343 0.000
M25.43 Effusion of joint (Forearm)
0.657 0.343 0.000
M25.42 Effusion of joint (Upper arm)
0.657 0.343 0.000
M25.41 Effusion of joint (Shoulder region)
0.657 0.343 0.000
M25.40 Effusion of joint (Multiple sites)
0.657 0.343 0.000
O66 Other obstructed labour
0.654 0.346 0.000
M80 Osteoporosis with pathological fracture
0.654 0.346 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.654 0.346 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.653 0.347 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.653 0.347 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.653 0.347 0.000
C09 Malignant neoplasm of tonsil
0.653 0.347 0.000
Z95.1 Presence of aortocoronary bypass graft
0.653 0.347 0.000
M65.8 Other synovitis and tenosynovitis
0.652 0.348 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.652 0.348 0.000
M65.2 Calcific tendinitis
0.652 0.348 0.000
M65.1 Other infective (teno)synovitis
0.652 0.348 0.000
M65.0 Abscess of tendon sheath
0.652 0.348 0.000
S22.9 Fracture of bony thorax, part unspecified
0.652 0.348 0.000
S22.8 Fracture of other parts of bony thorax
0.652 0.348 0.000
S22.5 Flail chest
0.652 0.348 0.000
S22.1 Multiple fractures of thoracic spine
0.652 0.348 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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