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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116876575
log Bayes Factor = 16.1237
Chromosome 22   position 49,899,208  (GRCh37) Explore rs116876575 on Ensembl!
Variant rs116876575 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I51 Complications and ill-defined descriptions of heart disease
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.992 0.008 0.000
Chapter II Neoplasms
0.991 0.009 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.991 0.009 0.000
H02 Other disorders of eyelid
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
N30-N39 Other diseases of urinary system
0.988 0.012 0.000
O60-O75 Complications of labour and delivery
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.983 0.017 0.000
I51.7 Cardiomegaly
0.983 0.017 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.983 0.017 0.000
N32 Other disorders of bladder
0.982 0.018 0.000
E70-E90 Metabolic disorders
0.980 0.020 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.977 0.023 0.000
N60-N64 Disorders of breast
0.975 0.025 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.973 0.027 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.969 0.031 0.000
N00-N08 Glomerular diseases
0.967 0.033 0.000
N17-N19 Renal failure
0.967 0.033 0.000
I47 Paroxysmal tachycardia
0.959 0.041 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.959 0.041 0.000
N32.8 Other specified disorders of bladder
0.958 0.042 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.957 0.043 0.000
Z80 Family history of malignant neoplasm
0.957 0.043 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.953 0.047 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.952 0.048 0.000
H02.4 Ptosis of eyelid
0.950 0.050 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.944 0.056 0.000
I51.8 Other ill-defined heart diseases
0.944 0.056 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.943 0.057 0.000
Z80.3 Family history of malignant neoplasm of breast
0.941 0.059 0.000
L20-L30 Dermatitis and eczema
0.938 0.062 0.000
E86 Volume depletion
0.934 0.066 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.929 0.071 0.000
H02.0 Entropion and trichiasis of eyelid
0.928 0.072 0.000
N18 Chronic renal failure
0.922 0.078 0.000
N10-N16 Renal tubulo-interstitial diseases
0.919 0.081 0.000
Z94 Transplanted organ and tissue status
0.917 0.083 0.000
C51-C58 Malignant neoplasms of female genital organs
0.913 0.087 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.912 0.088 0.000
N32.3 Diverticulum of bladder
0.911 0.089 0.000
I26 Pulmonary embolism
0.909 0.091 0.000
N03 Chronic nephritic syndrome
0.909 0.091 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.906 0.094 0.000
C64-C68 Malignant neoplasms of urinary tract
0.906 0.094 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.904 0.096 0.000
Q60-Q64 Congenital malformations of the urinary system
0.903 0.097 0.000
Y43 Primarily systemic agents
0.903 0.097 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.903 0.097 0.000
Z13 Special screening examination for other diseases and disorders
0.902 0.098 0.000
E87.7 Fluid overload
0.901 0.099 0.000
N61 Inflammatory disorders of breast
0.899 0.101 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.897 0.103 0.000
I47.1 Supraventricular tachycardia
0.892 0.108 0.000
I05-I09 Chronic rheumatic heart diseases
0.891 0.109 0.000
O47 False labour
0.885 0.115 0.000
Z36 Antenatal screening
0.884 0.116 0.000
E87.5 Hyperkalaemia
0.879 0.121 0.000
M65-M68 Disorders of synovium and tendon
0.879 0.121 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.878 0.122 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.878 0.122 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.872 0.128 0.000
H02.5 Other disorders affecting eyelid function
0.872 0.128 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.871 0.129 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.871 0.129 0.000
N63 Unspecified lump in breast
0.871 0.129 0.000
N03.9 Unspecified
0.868 0.132 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.867 0.133 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.864 0.136 0.000
E20-E35 Disorders of other endocrine glands
0.863 0.137 0.000
I34 Nonrheumatic mitral valve disorders
0.859 0.141 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.855 0.145 0.000
H02.3 Blepharochalasis
0.855 0.145 0.000
O36 Maternal care for other known or suspected foetal problems
0.854 0.146 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.851 0.149 0.000
M65 Synovitis and tenosynovitis
0.849 0.151 0.000
C67 Malignant neoplasm of bladder
0.849 0.151 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.847 0.153 0.000
I47.2 Ventricular tachycardia
0.846 0.154 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.843 0.157 0.000
Z85 Personal history of malignant neoplasm
0.842 0.158 0.000
I35 Nonrheumatic aortic valve disorders
0.841 0.159 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.841 0.159 0.000
N25-N29 Other disorders of kidney and ureter
0.840 0.160 0.000
L29 Pruritus
0.838 0.162 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.837 0.163 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.836 0.164 0.000
N30 Cystitis
0.836 0.164 0.000
Z13.9 Special screening examination, unspecified
0.834 0.166 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.832 0.168 0.000
Chapter VI Diseases of the nervous system
0.831 0.169 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.830 0.170 0.000
O00-O08 Pregnancy with abortive outcome
0.829 0.171 0.000
C56 Malignant neoplasm of ovary
0.829 0.171 0.000
H02.6 Xanthelasma of eyelid
0.826 0.174 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.826 0.174 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.824 0.176 0.000
M80-M85 Disorders of bone density and structure
0.824 0.176 0.000
L60-L75 Disorders of skin appendages
0.822 0.178 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.821 0.179 0.000
O44 Placenta praevia
0.819 0.181 0.000
Z46 Fitting and adjustment of other devices
0.818 0.182 0.000
Z30 Contraceptive management
0.818 0.182 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.818 0.182 0.000
N62 Hypertrophy of breast
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
L27 Dermatitis due to substances taken internally
0.816 0.184 0.000
Chapter I Certain infectious and parasitic diseases
0.813 0.187 0.000
E87.2 Acidosis
0.813 0.187 0.000
I08 Multiple valve diseases
0.813 0.187 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.811 0.189 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.810 0.190 0.000
N18.3 Chronic kidney disease, stage 3
0.810 0.190 0.000
N04 Nephrotic syndrome
0.810 0.190 0.000
O43 Placental disorders
0.809 0.191 0.000
Z34 Supervision of normal pregnancy
0.808 0.192 0.000
Z45 Adjustment and management of implanted device
0.808 0.192 0.000
Y42.5 Other oestrogens and progestogens
0.806 0.194 0.000
Z94.0 Kidney transplant status
0.806 0.194 0.000
Chapter VIII Diseases of the ear and mastoid process
0.806 0.194 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.805 0.195 0.000
H02.8 Other specified disorders of eyelid
0.804 0.196 0.000
Y43.3 Other antineoplastic drugs
0.804 0.196 0.000
I51.0 Cardiac septal defect, acquired
0.803 0.197 0.000
I42 Cardiomyopathy
0.802 0.198 0.000
L89 Decubitus ulcer
0.802 0.198 0.000
W00-W19 Falls
0.802 0.198 0.000
Z88.6 Personal history of allergy to analgesic agent
0.801 0.199 0.000
O63 Long labour
0.801 0.199 0.000
O72 Postpartum haemorrhage
0.799 0.201 0.000
N36 Other disorders of urethra
0.798 0.202 0.000
C34 Malignant neoplasm of bronchus and lung
0.798 0.202 0.000
Z89 Acquired absence of limb
0.797 0.202 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.797 0.203 0.000
Q63 Other congenital malformations of kidney
0.793 0.207 0.000
M65.3 Trigger finger
0.791 0.209 0.000
N99-N99 Other disorders of the genitourinary system
0.790 0.210 0.000
N18.0 End-stage renal disease
0.788 0.212 0.000
N64 Other disorders of breast
0.786 0.214 0.000
Z37 Outcome of delivery
0.785 0.215 0.000
H04 Disorders of lachrymal system
0.784 0.216 0.000
C32 Malignant neoplasm of larynx
0.782 0.218 0.000
N17 Acute renal failure
0.782 0.218 0.000
Q61 Cystic kidney disease
0.782 0.218 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.780 0.219 0.000
Z94.8 Other transplanted organ and tissue status
0.780 0.220 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.780 0.220 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.776 0.224 0.000
H10-H13 Disorders of conjunctiva
0.775 0.225 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.775 0.225 0.000
Z36.8 Other antenatal screening
0.773 0.227 0.000
C92 Myeloid leukaemia
0.771 0.229 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.771 0.229 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.770 0.230 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.769 0.231 0.000
E89.0 Postprocedural hypothyroidism
0.767 0.233 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.767 0.233 0.000
L29.0 Pruritus ani
0.766 0.234 0.000
Y40 Systemic antibiotics
0.766 0.234 0.000
I44 Atrioventricular and left bundle-branch block
0.763 0.236 0.000
L81 Other disorders of pigmentation
0.763 0.237 0.000
Z12 Special screening examination for neoplasms
0.762 0.238 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.762 0.238 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.761 0.239 0.000
H40-H42 Glaucoma
0.761 0.239 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.760 0.240 0.000
E83 Disorders of mineral metabolism
0.760 0.240 0.000
L50-L54 Urticaria and erythema
0.760 0.240 0.000
Z30.2 Sterilisation
0.759 0.241 0.000
Z98 Other postsurgical states
0.758 0.241 0.000
C91 Lymphoid leukaemia
0.758 0.242 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.758 0.242 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.758 0.242 0.000
Y43.0 Antiallergic and antiemetic drugs
0.757 0.243 0.000
N32.9 Bladder disorder, unspecified
0.755 0.245 0.000
Z46.6 Fitting and adjustment of urinary device
0.755 0.245 0.000
L85 Other epidermal thickening
0.754 0.246 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.754 0.246 0.000
O73 Retained placenta and membranes, without haemorrhage
0.753 0.247 0.000
I27 Other pulmonary heart diseases
0.752 0.248 0.000
L84 Corns and callosities
0.752 0.248 0.000
Z99.2 Dependence on renal dialysis
0.752 0.248 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.752 0.248 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.751 0.249 0.000
I50 Heart failure
0.751 0.249 0.000
Z52 Donors of organs and tissues
0.750 0.250 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.750 0.250 0.000
H55-H59 Other disorders of eye and adnexa
0.750 0.250 0.000
M65.34 Trigger finger-Hand
0.750 0.250 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.749 0.250 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.748 0.252 0.000
N19 Unspecified renal failure
0.748 0.252 0.000
L20 Atopic dermatitis
0.748 0.252 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.747 0.253 0.000
H02.1 Ectropion of eyelid
0.747 0.253 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.746 0.254 0.000
Q80-Q89 Other congenital malformations
0.745 0.255 0.000
G30-G32 Other degenerative diseases of the nervous system
0.743 0.257 0.000
N18.5 Chronic kidney disease, stage 5
0.743 0.257 0.000
L40-L45 Papulosquamous disorders
0.742 0.258 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.742 0.258 0.000
C67.3 Anterior wall of bladder
0.741 0.259 0.000
O36.8 Maternal care for other specified foetal problems
0.740 0.260 0.000
N05 Unspecified nephritic syndrome
0.739 0.261 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.739 0.261 0.000
V80-V89 Other land transport accidents
0.738 0.261 0.000
N13 Obstructive and reflux uropathy
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.738 0.262 0.000
C51 Malignant neoplasm of vulva
0.737 0.263 0.000
Z39 Postpartum care and examination
0.736 0.264 0.000
Z49 Care involving dialysis
0.736 0.264 0.000
N20-N23 Urolithiasis
0.736 0.264 0.000
Y52 Agents primarily affecting the cardiovascular system
0.734 0.266 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.732 0.268 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.731 0.269 0.000
E23 Hypofunction and other disorders of pituitary gland
0.729 0.271 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.729 0.271 0.000
Z94.7 Corneal transplant status
0.729 0.271 0.000
E88 Other metabolic disorders
0.728 0.272 0.000
X60-X84 Intentional self-harm
0.727 0.273 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.726 0.274 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.726 0.274 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.725 0.275 0.000
Z97 Presence of other devices
0.724 0.275 0.000
H01 Other inflammation of eyelid
0.724 0.276 0.000
Z01.9 Special examination, unspecified
0.724 0.276 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.724 0.276 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.723 0.277 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.722 0.278 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.722 0.278 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.722 0.278 0.000
Z85.6 Personal history of leukaemia
0.722 0.278 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.720 0.280 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.719 0.281 0.000
O66 Other obstructed labour
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.717 0.283 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
H80-H83 Diseases of inner ear
0.715 0.285 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.715 0.285 0.000
E89.3 Postprocedural hypopituitarism
0.713 0.287 0.000
I51.6 Cardiovascular disease, unspecified
0.713 0.287 0.000
I51.5 Myocardial degeneration
0.713 0.287 0.000
I51.4 Myocarditis, unspecified
0.713 0.287 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.713 0.287 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.713 0.287 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.713 0.287 0.000
I44.7 Left bundle-branch block, unspecified
0.712 0.288 0.000
M81 Osteoporosis without pathological fracture
0.712 0.288 0.000
M67 Other disorders of synovium and tendon
0.712 0.288 0.000
C66 Malignant neoplasm of ureter
0.712 0.288 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.289 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.710 0.289 0.000
H05 Disorders of orbit
0.710 0.289 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.710 0.289 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.710 0.290 0.000
H02.2 Lagophthalmos
0.710 0.290 0.000
Z54 Convalescence
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
O62 Abnormalities of forces of labour
0.710 0.290 0.000
Y44 Agents primarily affecting blood constituents
0.710 0.290 0.000
O44.1 Placenta praevia with haemorrhage
0.709 0.291 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
N37 Urethral disorders in diseases classified elsewhere
0.708 0.291 0.000
N34 Urethritis and urethral syndrome
0.708 0.291 0.000
N33 Bladder disorders in diseases classified elsewhere
0.708 0.291 0.000
H43-H45 Disorders of vitreous body and globe
0.708 0.291 0.000
O74 Complications of anaesthesia during labour and delivery
0.708 0.292 0.000
O71 Other obstetric trauma
0.708 0.292 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.708 0.292 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.708 0.292 0.000
O61 Failed induction of labour
0.708 0.292 0.000
O60 Preterm delivery
0.708 0.292 0.000
L71 Rosacea
0.708 0.292 0.000
N35 Urethral stricture
0.707 0.293 0.000
N32.0 Bladder-neck obstruction
0.706 0.294 0.000
Q00-Q07 Congenital malformations of the nervous system
0.705 0.295 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.705 0.295 0.000
Y59 Other and unspecified vaccines and biological substances
0.705 0.295 0.000
Y58 Bacterial vaccines
0.705 0.295 0.000
Y57 Other and unspecified drugs and medicaments
0.705 0.295 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.705 0.295 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.705 0.295 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.705 0.295 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.705 0.295 0.000
Y48 Anaesthetics and therapeutic gases
0.705 0.295 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.705 0.295 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.705 0.295 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
I34.1 Mitral (valve) prolapse
0.704 0.296 0.000
Z83 Family history of other specific disorders
0.704 0.296 0.000
I34.0 Mitral (valve) insufficiency
0.704 0.296 0.000
N32.4 Rupture of bladder, nontraumatic
0.704 0.296 0.000
N32.2 Vesical fistula, not elsewhere classified
0.704 0.296 0.000
N32.1 Vesicointestinal fistula
0.704 0.296 0.000
E85 Amyloidosis
0.703 0.297 0.000
E84 Cystic fibrosis
0.703 0.297 0.000
E79 Disorders of purine and pyrimidine metabolism
0.703 0.297 0.000
E77 Disorders of glycoprotein metabolism
0.703 0.297 0.000
E76 Disorders of glycosaminoglycan metabolism
0.703 0.297 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.703 0.297 0.000
E74 Other disorders of carbohydrate metabolism
0.703 0.297 0.000
E73 Lactose intolerance
0.703 0.297 0.000
E72 Other disorders of amino-acid metabolism
0.703 0.297 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.703 0.297 0.000
E70 Disorders of aromatic amino-acid metabolism
0.703 0.297 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.703 0.297 0.000
Y42.7 Androgens and anabolic congeners
0.702 0.298 0.000
E40-E46 Malnutrition
0.702 0.298 0.000
Z84 Family history of other conditions
0.700 0.300 0.000
Z81 Family history of mental and behavioural disorders
0.700 0.300 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.699 0.301 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.698 0.302 0.000
O45 Premature separation of placenta [abruptio placentae]
0.697 0.303 0.000
O41 Other disorders of amniotic fluid and membranes
0.697 0.303 0.000
O33 Maternal care for known or suspected disproportion
0.697 0.303 0.000
O31 Complications specific to multiple gestation
0.697 0.303 0.000
O40 Polyhydramnios
0.697 0.303 0.000
N04.9 Unspecified
0.697 0.303 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.696 0.304 0.000
N30.8 Other cystitis
0.695 0.305 0.000
Z38 Liveborn infants according to place of birth
0.695 0.305 0.000
Z32 Pregnancy examination and test
0.695 0.305 0.000
Z31 Procreative management
0.695 0.305 0.000
E22 Hyperfunction of pituitary gland
0.693 0.306 0.000
O48 Prolonged pregnancy
0.693 0.306 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.693 0.307 0.000
N06 Isolated proteinuria with specified morphological lesion
0.693 0.307 0.000
N01 Rapidly progressive nephritic syndrome
0.693 0.307 0.000
N00 Acute nephritic syndrome
0.693 0.307 0.000
C34.9 Bronchus or lung, unspecified
0.693 0.307 0.000
I42.9 Cardiomyopathy, unspecified
0.692 0.308 0.000
N18.2 Chronic kidney disease, stage 2
0.691 0.309 0.000
Z02 Examination and encounter for administrative purposes
0.691 0.309 0.000
Z82.3 Family history of stroke
0.690 0.310 0.000
I35.8 Other aortic valve disorders
0.689 0.311 0.000
E87.0 Hyperosmolality and hypernatraemia
0.689 0.311 0.000
V10-V19 Pedal cyclist injured in transport accident
0.689 0.311 0.000
Z40 Prophylactic surgery
0.689 0.311 0.000
M84 Disorders of continuity of bone
0.688 0.312 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.688 0.312 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.687 0.312 0.000
I47.0 Reentry ventricular arrhythmia
0.687 0.312 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.687 0.312 0.000
E87.4 Mixed disorder of acid-base balance
0.686 0.313 0.000
E87.3 Alkalosis
0.686 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.686 0.313 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.313 0.000
Q50-Q56 Congenital malformations of genital organs
0.686 0.313 0.000
Q35-Q37 Cleft lip and cleft palate
0.686 0.313 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.686 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.686 0.313 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.686 0.314 0.000
Z80.6 Family history of leukaemia
0.686 0.314 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.686 0.314 0.000
Z99.8 Dependence on other enabling machines and devices
0.686 0.314 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.686 0.314 0.000
C67.2 Lateral wall of bladder
0.684 0.316 0.000
I33 Acute and subacute endocarditis
0.683 0.316 0.000
N64.5 Other signs and symptoms in breast
0.684 0.316 0.000
I28 Other diseases of pulmonary vessels
0.683 0.317 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.683 0.317 0.000
Z10 Routine general health check-up of defined subpopulation
0.683 0.317 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.682 0.317 0.000
M60-M63 Disorders of muscles
0.682 0.318 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.682 0.318 0.000
Z45.2 Adjustment and management of vascular access device
0.681 0.319 0.000
C67.5 Bladder neck
0.680 0.320 0.000
L28 Lichen simplex chronicus and prurigo
0.680 0.320 0.000
Z13.1 Special screening examination for diabetes mellitus
0.678 0.322 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.678 0.322 0.000
N18.4 Chronic kidney disease, stage 4
0.678 0.322 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.677 0.323 0.000
C95 Leukaemia of unspecified cell type
0.677 0.323 0.000
C94 Other leukaemias of specified cell type
0.677 0.323 0.000
C93 Monocytic leukaemia
0.677 0.323 0.000
C88 Malignant immunoproliferative diseases
0.677 0.323 0.000
C86 Other specified types of T/NK-cell lymphoma
0.677 0.323 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.677 0.323 0.000
C81 Hodgkin's disease
0.677 0.323 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.677 0.323 0.000
E83.4 Disorders of magnesium metabolism
0.677 0.323 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.676 0.324 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.676 0.324 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.676 0.324 0.000
L94 Other localised connective tissue disorders
0.676 0.324 0.000
L93 Lupus erythematosus
0.676 0.324 0.000
L87 Transepidermal elimination disorders
0.676 0.324 0.000
L88 Pyoderma gangrenosum
0.676 0.324 0.000
L86 Keratoderma in diseases classified elsewhere
0.676 0.324 0.000
L83 Acanthosis nigricans
0.676 0.324 0.000
L80 Vitiligo
0.676 0.324 0.000
O80-O84 Delivery
0.676 0.324 0.000
O00 Ectopic pregnancy
0.676 0.324 0.000
Z01.4 Gynaecological examination (general)(routine)
0.675 0.325 0.000
Q63.0 Accessory kidney
0.673 0.327 0.000
L25 Unspecified contact dermatitis
0.672 0.328 0.000
L24 Irritant contact dermatitis
0.672 0.328 0.000
L23 Allergic contact dermatitis
0.672 0.328 0.000
L21 Seborrhoeic dermatitis
0.672 0.328 0.000
L26 Exfoliative dermatitis
0.672 0.328 0.000
L22 Diaper [napkin] dermatitis
0.672 0.328 0.000
L60 Nail disorders
0.672 0.328 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.672 0.328 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.671 0.329 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.669 0.331 0.000
G20-G26 Extrapyramidal and movement disorders
0.668 0.332 0.000
C32.9 Larynx, unspecified
0.668 0.332 0.000
C67.4 Posterior wall of bladder
0.668 0.332 0.000
E27 Other disorders of adrenal gland
0.668 0.332 0.000
N18.9 Chronic renal failure, unspecified
0.668 0.332 0.000
E28 Ovarian dysfunction
0.667 0.332 0.000
C60-C63 Malignant neoplasms of male genital organs
0.667 0.333 0.000
O30 Multiple gestation
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.667 0.333 0.000
O04 Medical abortion
0.667 0.333 0.000
C34.2 Middle lobe, bronchus or lung
0.666 0.333 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.666 0.334 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.666 0.334 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.666 0.334 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.666 0.334 0.000
Z82.2 Family history of deafness and hearing loss
0.666 0.334 0.000
Z82.1 Family history of blindness and visual loss
0.666 0.334 0.000
Z89.5 Acquired absence of leg at or below knee
0.665 0.335 0.000
Z34.8 Supervision of other normal pregnancy
0.665 0.335 0.000
N30.1 Interstitial cystitis (chronic)
0.664 0.336 0.000
G90-G99 Other disorders of the nervous system
0.664 0.336 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.663 0.337 0.000
C92.1 Chronic myeloid leukaemia
0.662 0.338 0.000
Z37.0 Single live birth
0.661 0.339 0.000
H04.2 Epiphora
0.661 0.339 0.000
N18.8 Other chronic renal failure
0.661 0.339 0.000
N18.1 Chronic kidney disease, stage 1
0.661 0.339 0.000
C54 Malignant neoplasm of corpus uteri
0.660 0.340 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.659 0.341 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.659 0.341 0.000
N15 Other renal tubulo-interstitial diseases
0.659 0.341 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.659 0.341 0.000
N11 Chronic tubulo-interstitial nephritis
0.659 0.341 0.000
S90-S99 Injuries to the ankle and foot
0.659 0.341 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.658 0.342 0.000
Z94.6 Bone transplant status
0.658 0.342 0.000
Z94.5 Skin transplant status
0.658 0.342 0.000
Z94.4 Liver transplant status
0.658 0.342 0.000
Z94.3 Heart and lungs transplant status
0.658 0.342 0.000
Z94.2 Lung transplant status
0.658 0.342 0.000
Z94.1 Heart transplant status
0.658 0.342 0.000
I31 Other diseases of pericardium
0.657 0.343 0.000
D46 Myelodysplastic syndromes
0.657 0.343 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.656 0.344 0.000
O47.9 False labour, unspecified
0.656 0.344 0.000
I08.0 Disorders of both mitral and aortic valves
0.656 0.344 0.000
M86-M90 Other osteopathies
0.655 0.345 0.000
O43.8 Other placental disorders
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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