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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116989098
log Bayes Factor = 17.9744
Chromosome 6   position 161,777,500  (GRCh37) Explore rs116989098 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
I20.9 Angina pectoris, unspecified
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.996 0.004 0.000
Chapter II Neoplasms
0.988 0.012 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.986 0.014 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.985 0.015 0.000
I20.0 Unstable angina
0.980 0.020 0.000
H40-H42 Glaucoma
0.976 0.024 0.000
Chapter VIII Diseases of the ear and mastoid process
0.975 0.025 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.972 0.028 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.965 0.035 0.000
I47 Paroxysmal tachycardia
0.964 0.036 0.000
D00-D09 In situ neoplasms
0.963 0.037 0.000
H40 Glaucoma
0.959 0.041 0.000
I51 Complications and ill-defined descriptions of heart disease
0.958 0.042 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.945 0.055 0.000
H30-H36 Disorders of choroid and retina
0.941 0.059 0.000
H60-H62 Diseases of external ear
0.937 0.063 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.935 0.065 0.000
S00-S09 Injuries to the head
0.935 0.065 0.000
I24 Other acute ischaemic heart diseases
0.933 0.067 0.000
Chapter XX External causes of morbidity and mortality
0.930 0.070 0.000
Z93 Artificial opening status
0.930 0.070 0.000
D05 Carcinoma in situ of breast
0.925 0.075 0.000
Z95.1 Presence of aortocoronary bypass graft
0.925 0.075 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.921 0.079 0.000
I45 Other conduction disorders
0.912 0.088 0.000
I51.7 Cardiomegaly
0.909 0.091 0.000
I74 Arterial embolism and thrombosis
0.907 0.093 0.000
H35 Other retinal disorders
0.906 0.094 0.000
I47.1 Supraventricular tachycardia
0.904 0.096 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.903 0.097 0.000
H10-H13 Disorders of conjunctiva
0.900 0.100 0.000
H61 Other disorders of external ear
0.898 0.102 0.000
H65-H75 Diseases of middle ear and mastoid
0.897 0.103 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.896 0.104 0.000
D05.1 Intraductal carcinoma in situ
0.896 0.104 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.896 0.104 0.000
Z95.2 Presence of prosthetic heart valve
0.892 0.108 0.000
H40.9 Glaucoma, unspecified
0.890 0.110 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.889 0.111 0.000
H40.1 Primary open-angle glaucoma
0.888 0.112 0.000
I35 Nonrheumatic aortic valve disorders
0.888 0.112 0.000
I20.8 Other forms of angina pectoris
0.886 0.114 0.000
Z13 Special screening examination for other diseases and disorders
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
Z02 Examination and encounter for administrative purposes
0.884 0.116 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.881 0.119 0.000
I33 Acute and subacute endocarditis
0.880 0.120 0.000
E78.5 Hyperlipidaemia, unspecified
0.876 0.124 0.000
I25.1 Atherosclerotic heart disease
0.876 0.124 0.000
C64-C68 Malignant neoplasms of urinary tract
0.875 0.125 0.000
M70-M79 Other soft tissue disorders
0.872 0.128 0.000
Z93.3 Colostomy status
0.870 0.130 0.000
M45-M49 Spondylopathies
0.867 0.133 0.000
H40.0 Glaucoma suspect
0.866 0.134 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.866 0.134 0.000
Z95.4 Presence of other heart-valve replacement
0.865 0.135 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.865 0.135 0.000
I71 Aortic aneurysm and dissection
0.865 0.135 0.000
M65-M68 Disorders of synovium and tendon
0.864 0.136 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.863 0.137 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.862 0.138 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.861 0.139 0.000
I84 Haemorrhoids
0.857 0.143 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.852 0.148 0.000
I47.2 Ventricular tachycardia
0.850 0.150 0.000
H52 Disorders of refraction and accommodation
0.847 0.153 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.846 0.154 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.844 0.156 0.000
I72 Other aneurysm
0.842 0.158 0.000
I45.1 Other and unspecified right bundle-branch block
0.842 0.158 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.838 0.162 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.835 0.165 0.000
Chapter I Certain infectious and parasitic diseases
0.835 0.165 0.000
I77 Other disorders of arteries and arterioles
0.833 0.167 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.833 0.167 0.000
H11 Other disorders of conjunctiva
0.829 0.171 0.000
I35.0 Aortic (valve) stenosis
0.829 0.171 0.000
I84.6 Residual haemorrhoidal skin tags
0.828 0.172 0.000
E78.1 Pure hyperglyceridaemia
0.828 0.172 0.000
E20-E35 Disorders of other endocrine glands
0.826 0.174 0.000
E83 Disorders of mineral metabolism
0.825 0.175 0.000
H61.0 Perichondritis of external ear
0.822 0.178 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.821 0.179 0.000
M75 Shoulder lesions
0.819 0.181 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.819 0.181 0.000
I51.8 Other ill-defined heart diseases
0.817 0.183 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.817 0.183 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
H73 Other disorders of tympanic membrane
0.814 0.186 0.000
I84.2 Internal haemorrhoids without complication
0.813 0.187 0.000
Z02.8 Other examinations for administrative purposes
0.811 0.189 0.000
Z99.8 Dependence on other enabling machines and devices
0.810 0.190 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.808 0.192 0.000
H35.3 Degeneration of macula and posterior pole
0.807 0.193 0.000
S20-S29 Injuries to the thorax
0.807 0.193 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.806 0.194 0.000
I37 Pulmonary valve disorders
0.805 0.195 0.000
I60-I69 Cerebrovascular diseases
0.802 0.198 0.000
C15-C26 Malignant neoplasms of digestive organs
0.800 0.200 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.799 0.201 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.798 0.202 0.000
Z99.1 Dependence on respirator
0.797 0.203 0.000
T88.4 Failed or difficult intubation
0.796 0.204 0.000
D10-D36 Benign neoplasms
0.795 0.205 0.000
I33.0 Acute and subacute infective endocarditis
0.795 0.205 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.792 0.208 0.000
H35.7 Separation of retinal layers
0.790 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
D03 Melanoma in situ
0.790 0.210 0.000
S01 Open wound of head
0.788 0.212 0.000
S00 Superficial injury of head
0.788 0.212 0.000
M47 Spondylosis
0.787 0.213 0.000
H52.1 Myopia
0.787 0.213 0.000
Z93.2 Ileostomy status
0.787 0.213 0.000
I05-I09 Chronic rheumatic heart diseases
0.787 0.213 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.784 0.216 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.784 0.216 0.000
S70-S79 Injuries to the hip and thigh
0.783 0.217 0.000
Q60-Q64 Congenital malformations of the urinary system
0.783 0.217 0.000
I25.2 Old myocardial infarction
0.779 0.221 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.777 0.223 0.000
C51-C58 Malignant neoplasms of female genital organs
0.776 0.224 0.000
A30-A49 Other bacterial diseases
0.773 0.227 0.000
I49 Other cardiac arrhythmias
0.770 0.230 0.000
H65 Nonsuppurative otitis media
0.769 0.231 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.769 0.231 0.000
I31 Other diseases of pericardium
0.766 0.234 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.766 0.234 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.765 0.235 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.764 0.236 0.000
H49 Paralytic strabismus
0.764 0.236 0.000
I46 Cardiac arrest
0.764 0.236 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.763 0.237 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.762 0.238 0.000
H25-H28 Disorders of lens
0.762 0.238 0.000
D09 Carcinoma in situ of other and unspecified sites
0.761 0.239 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.761 0.239 0.000
I38 Endocarditis, valve unspecified
0.758 0.241 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.757 0.243 0.000
Z93.6 Other artificial openings of urinary tract status
0.756 0.244 0.000
I70 Atherosclerosis
0.755 0.245 0.000
Y44 Agents primarily affecting blood constituents
0.755 0.245 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
I74.5 Embolism and thrombosis of iliac artery
0.754 0.246 0.000
S05 Injury of eye and orbit
0.754 0.246 0.000
H73.8 Other specified disorders of tympanic membrane
0.754 0.246 0.000
Z03.8 Observation for other suspected diseases and conditions
0.754 0.246 0.000
D12.4 Descending colon
0.754 0.246 0.000
Z04 Examination and observation for other reasons
0.754 0.246 0.000
H60 Otitis externa
0.754 0.246 0.000
S09 Other and unspecified injuries of head
0.754 0.246 0.000
Z95.3 Presence of xenogenic heart valve
0.753 0.247 0.000
D05.0 Lobular carcinoma in situ
0.751 0.249 0.000
M67 Other disorders of synovium and tendon
0.748 0.251 0.000
Z13.1 Special screening examination for diabetes mellitus
0.747 0.253 0.000
D04 Carcinoma in situ of skin
0.746 0.254 0.000
T82.3 Mechanical complication of other vascular grafts
0.746 0.254 0.000
H61.9 Disorder of external ear, unspecified
0.745 0.255 0.000
H61.2 Impacted cerumen
0.744 0.256 0.000
Z60 Problems related to social environment
0.741 0.259 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.741 0.259 0.000
Z36 Antenatal screening
0.740 0.260 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.739 0.261 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.738 0.262 0.000
T79-T79 Certain early complications of trauma
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.737 0.263 0.000
I30 Acute pericarditis
0.733 0.266 0.000
I73 Other peripheral vascular diseases
0.732 0.268 0.000
Z93.0 Tracheostomy status
0.729 0.271 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.728 0.272 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.728 0.272 0.000
I25.3 Aneurysm of heart
0.727 0.272 0.000
M20-M25 Other joint disorders
0.727 0.273 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.726 0.274 0.000
I20.1 Angina pectoris with documented spasm
0.725 0.275 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.722 0.278 0.000
H35.8 Other specified retinal disorders
0.722 0.278 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.721 0.279 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.721 0.279 0.000
M60-M63 Disorders of muscles
0.721 0.279 0.000
E00-E07 Disorders of thyroid gland
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.719 0.281 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
A41 Other septicaemia
0.717 0.283 0.000
E78.8 Other disorders of lipoprotein metabolism
0.716 0.283 0.000
E78.6 Lipoprotein deficiency
0.716 0.283 0.000
E78.4 Other hyperlipidaemia
0.716 0.283 0.000
E78.3 Hyperchylomicronaemia
0.716 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
E85 Amyloidosis
0.715 0.284 0.000
E84 Cystic fibrosis
0.715 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.284 0.000
E73 Lactose intolerance
0.715 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.285 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.714 0.286 0.000
H35.6 Retinal haemorrhage
0.714 0.286 0.000
S01.5 Open wound of lip and oral cavity
0.713 0.287 0.000
T82.1 Mechanical complication of cardiac electronic device
0.713 0.287 0.000
M40-M43 Deforming dorsopathies
0.712 0.288 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.712 0.288 0.000
E78.2 Mixed hyperlipidaemia
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
M75.2 Bicipital tendinitis
0.712 0.288 0.000
M65 Synovitis and tenosynovitis
0.711 0.288 0.000
E27 Other disorders of adrenal gland
0.711 0.289 0.000
Q61 Cystic kidney disease
0.710 0.290 0.000
Chapter VI Diseases of the nervous system
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.708 0.292 0.000
T33-T35 Frostbite
0.707 0.293 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.293 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.293 0.000
I77.6 Arteritis, unspecified
0.707 0.293 0.000
E83.5 Disorders of calcium metabolism
0.707 0.293 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
Z10 Routine general health check-up of defined subpopulation
0.706 0.294 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.706 0.294 0.000
H33 Retinal detachments and breaks
0.705 0.295 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.704 0.296 0.000
I22 Subsequent myocardial infarction
0.703 0.297 0.000
M86-M90 Other osteopathies
0.703 0.297 0.000
S06 Intracranial injury
0.703 0.297 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.701 0.299 0.000
I72.3 Aneurysm of iliac artery
0.700 0.300 0.000
T18 Foreign body in alimentary tract
0.700 0.300 0.000
H42 Glaucoma in diseases classified elsewhere
0.699 0.300 0.000
I82 Other venous embolism and thrombosis
0.698 0.302 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.698 0.302 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.697 0.303 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.697 0.303 0.000
M47.9 Spondylosis, unspecified
0.697 0.303 0.000
Z93.5 Cystostomy status
0.697 0.303 0.000
C45 Mesothelioma
0.696 0.303 0.000
Z84 Family history of other conditions
0.694 0.306 0.000
Z81 Family history of mental and behavioural disorders
0.694 0.306 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.692 0.308 0.000
M00-M03 Infectious arthropathies
0.692 0.308 0.000
Z87 Personal history of other diseases and conditions
0.692 0.308 0.000
I50 Heart failure
0.692 0.308 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.691 0.309 0.000
I47.0 Reentry ventricular arrhythmia
0.691 0.309 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.691 0.309 0.000
I24.8 Other forms of acute ischaemic heart disease
0.691 0.309 0.000
H34 Retinal vascular occlusions
0.691 0.309 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.690 0.310 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.690 0.310 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.690 0.310 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.690 0.310 0.000
I84.4 External haemorrhoids with other complications
0.688 0.312 0.000
H74 Other disorders of middle ear and mastoid
0.688 0.312 0.000
H40.5 Glaucoma secondary to other eye disorders
0.687 0.312 0.000
H40.8 Other glaucoma
0.687 0.312 0.000
H40.6 Glaucoma secondary to drugs
0.687 0.312 0.000
H40.4 Glaucoma secondary to eye inflammation
0.687 0.312 0.000
H40.3 Glaucoma secondary to eye trauma
0.687 0.312 0.000
I51.6 Cardiovascular disease, unspecified
0.687 0.313 0.000
I51.5 Myocardial degeneration
0.687 0.313 0.000
I51.4 Myocarditis, unspecified
0.687 0.313 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.687 0.313 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.687 0.313 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.687 0.313 0.000
I51.0 Cardiac septal defect, acquired
0.687 0.313 0.000
I45.6 Preexcitation syndrome
0.686 0.314 0.000
C54 Malignant neoplasm of corpus uteri
0.684 0.316 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.684 0.316 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.684 0.316 0.000
I78 Diseases of capillaries
0.683 0.317 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.682 0.318 0.000
D12.3 Transverse colon
0.682 0.318 0.000
V20-V29 Motorcycle rider injured in transport accident
0.682 0.318 0.000
H11.0 Pterygium
0.682 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.679 0.321 0.000
Z96 Presence of other functional implants
0.679 0.321 0.000
Y44.2 Anticoagulants
0.679 0.321 0.000
M24 Other specific joint derangements
0.679 0.321 0.000
T87 Complications peculiar to reattachment and amputation
0.678 0.322 0.000
T86 Failure and rejection of transplanted organs and tissues
0.678 0.322 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.677 0.323 0.000
Q80-Q89 Other congenital malformations
0.676 0.324 0.000
C71 Malignant neoplasm of brain
0.675 0.324 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.675 0.325 0.000
O60-O75 Complications of labour and delivery
0.675 0.325 0.000
H35.0 Background retinopathy and retinal vascular changes
0.675 0.325 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.674 0.325 0.000
H31 Other disorders of choroid
0.674 0.325 0.000
H30 Chorioretinal inflammation
0.674 0.325 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.672 0.328 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.672 0.328 0.000
H25 Senile cataract
0.671 0.329 0.000
H21 Other disorders of iris and ciliary body
0.671 0.329 0.000
M47.8 Other spondylosis
0.671 0.329 0.000
H52.3 Anisometropia and aniseikonia
0.671 0.329 0.000
S60-S69 Injuries to the wrist and hand
0.670 0.330 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.670 0.330 0.000
S08 Traumatic amputation of part of head
0.670 0.330 0.000
S07 Crushing injury of head
0.670 0.330 0.000
S04 Injury of cranial nerves
0.670 0.330 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
S70 Superficial injury of hip and thigh
0.670 0.330 0.000
I24.1 Dressler's syndrome
0.669 0.331 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.669 0.331 0.000
D36 Benign neoplasm of other and unspecified sites
0.669 0.331 0.000
I35.8 Other aortic valve disorders
0.667 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.667 0.333 0.000
Y10-Y34 Event of undetermined intent
0.667 0.333 0.000
Y00-Y09 Assault
0.667 0.333 0.000
X85-X99 Assault
0.667 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
X30-X39 Exposure to forces of nature
0.667 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
X10-X19 Contact with heat and hot substances
0.667 0.333 0.000
X00-X09 Exposure to smoke, fire and flames
0.667 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.667 0.333 0.000
W75-W84 Other accidental threats to breathing
0.667 0.333 0.000
W65-W74 Accidental drowning and submersion
0.667 0.333 0.000
V98-V99 Other and unspecified transport accidents
0.667 0.333 0.000
V95-V97 Air and space transport accidents
0.667 0.333 0.000
V90-V94 Water transport accidents
0.667 0.333 0.000
V80-V89 Other land transport accidents
0.667 0.333 0.000
V70-V79 Bus occupant injured in transport accident
0.667 0.333 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.667 0.333 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.667 0.333 0.000
V40-V49 Car occupant injured in transport accident
0.667 0.333 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.667 0.333 0.000
V01-V09 Pedestrian injured in transport accident
0.667 0.333 0.000
Z99.3 Dependence on wheelchair
0.667 0.333 0.000
Z93.9 Artificial opening status, unspecified
0.667 0.333 0.000
Z93.8 Other artificial opening status
0.667 0.333 0.000
I37.1 Pulmonary valve insufficiency
0.667 0.333 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.666 0.334 0.000
M45 Ankylosing spondylitis
0.666 0.334 0.000
M67.8 Other specified disorders of synovium and tendon
0.666 0.334 0.000
M75.1 Rotator cuff syndrome
0.665 0.335 0.000
S27 Injury of other and unspecified intrathoracic organs
0.663 0.336 0.000
D05.7 Other carcinoma in situ of breast
0.663 0.336 0.000
Y86 Sequelae of other accidents
0.663 0.337 0.000
I25.5 Ischaemic cardiomyopathy
0.663 0.337 0.000
E22 Hyperfunction of pituitary gland
0.663 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.662 0.338 0.000
M80-M85 Disorders of bone density and structure
0.662 0.338 0.000
I77.1 Stricture of artery
0.662 0.338 0.000
M75.3 Calcific tendinitis of shoulder
0.661 0.339 0.000
H51 Other disorders of binocular movement
0.660 0.340 0.000
S80-S89 Injuries to the knee and lower leg
0.660 0.340 0.000
C16 Malignant neoplasm of stomach
0.659 0.341 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.658 0.342 0.000
I27 Other pulmonary heart diseases
0.658 0.342 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.657 0.343 0.000
D29 Benign neoplasm of male genital organs
0.656 0.343 0.000
Y57 Other and unspecified drugs and medicaments
0.656 0.344 0.000
Z03.4 Observation for suspected myocardial infarction
0.656 0.344 0.000
C67 Malignant neoplasm of bladder
0.655 0.345 0.000
E04 Other non-toxic goitre
0.655 0.345 0.000
A80-A89 Viral infections of the central nervous system
0.655 0.345 0.000
Z60.2 Living alone
0.654 0.345 0.000
T90 Sequelae of injuries of head
0.654 0.346 0.000
I45.9 Conduction disorder, unspecified
0.654 0.346 0.000
I45.8 Other specified conduction disorders
0.654 0.346 0.000
I45.4 Nonspecific intraventricular block
0.654 0.346 0.000
I45.3 Trifascicular block
0.654 0.346 0.000
I45.2 Bifascicular block
0.654 0.346 0.000
I45.0 Right fascicular block
0.654 0.346 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.653 0.347 0.000
Q50-Q56 Congenital malformations of genital organs
0.652 0.348 0.000
I45.5 Other specified heart block
0.651 0.349 0.000
I49.5 Sick sinus syndrome
0.651 0.349 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.650 0.350 0.000
I74.8 Embolism and thrombosis of other arteries
0.650 0.350 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.650 0.350 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.650 0.350 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.650 0.350 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.650 0.350 0.000
H35.9 Retinal disorder, unspecified
0.650 0.350 0.000
H35.5 Hereditary retinal dystrophy
0.650 0.350 0.000
H35.2 Other proliferative retinopathy
0.650 0.350 0.000
H35.1 Retinopathy of prematurity
0.650 0.350 0.000
H17 Corneal scars and opacities
0.650 0.350 0.000
Z36.9 Antenatal screening, unspecified
0.650 0.350 0.000
Z57 Occupational exposure to risk-factors
0.650 0.350 0.000
H90-H95 Other disorders of ear
0.650 0.350 0.000
Z32 Pregnancy examination and test
0.649 0.351 0.000
Q61.3 Polycystic kidney, unspecified
0.648 0.352 0.000
Z39 Postpartum care and examination
0.648 0.352 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.648 0.352 0.000
Z99.4 Dependence on artificial heart
0.648 0.352 0.000
Z99.0 Dependence on aspirator
0.648 0.352 0.000
T93 Sequelae of injuries of lower limb
0.648 0.352 0.000
D12.1 Appendix
0.647 0.353 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.647 0.353 0.000
H25.8 Other senile cataract
0.646 0.354 0.000
D48.1 Connective and other soft tissue
0.646 0.354 0.000
S00.1 Contusion of eyelid and periocular area
0.646 0.354 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.645 0.354 0.000
H10 Conjunctivitis
0.645 0.354 0.000
S02 Fracture of skull and facial bones
0.645 0.354 0.000
S01.2 Open wound of nose
0.645 0.355 0.000
I87 Other disorders of veins
0.645 0.355 0.000
M77 Other enthesopathies
0.644 0.356 0.000
H61.8 Other specified disorders of external ear
0.644 0.356 0.000
H61.3 Acquired stenosis of external ear canal
0.644 0.356 0.000
H61.1 Non-infective disorders of pinna
0.644 0.356 0.000
E89.0 Postprocedural hypothyroidism
0.644 0.356 0.000
I72.8 Aneurysm of other specified arteries
0.644 0.356 0.000
I84.3 External thrombosed haemorrhoids
0.644 0.356 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.644 0.356 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.643 0.356 0.000
H70 Mastoiditis and related conditions
0.643 0.356 0.000
H69 Other disorders of Eustachian tube
0.643 0.356 0.000
H68 Eustachian salpingitis and obstruction
0.643 0.356 0.000
H67 Otitis media in diseases classified elsewhere
0.643 0.356 0.000
H43-H45 Disorders of vitreous body and globe
0.643 0.356 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.643 0.357 0.000
M75.5 Bursitis of shoulder
0.643 0.357 0.000
I88 Nonspecific lymphadenitis
0.642 0.357 0.000
H11.3 Conjunctival haemorrhage
0.642 0.357 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.642 0.358 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.642 0.358 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.642 0.358 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.642 0.358 0.000
D32 Benign neoplasm of meninges
0.642 0.358 0.000
H49.0 Third [oculomotor] nerve palsy
0.641 0.358 0.000
Z63 Other problems related to primary support group, including family circumstances
0.641 0.359 0.000
T91 Sequelae of injuries of neck and trunk
0.641 0.359 0.000
I51.9 Heart disease, unspecified
0.640 0.360 0.000
Z95.0 Presence of cardiac pacemaker
0.640 0.360 0.000
Z89 Acquired absence of limb
0.639 0.361 0.000
H65.2 Chronic serous otitis media
0.639 0.361 0.000
I49.0 Ventricular fibrillation and flutter
0.639 0.361 0.000
Y52 Agents primarily affecting the cardiovascular system
0.638 0.361 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.638 0.362 0.000
I46.9 Cardiac arrest, unspecified
0.638 0.362 0.000
H60.8 Other otitis externa
0.638 0.362 0.000
T88.9 Complication of surgical and medical care, unspecified
0.637 0.363 0.000
T88.5 Other complications of anaesthesia
0.637 0.363 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.637 0.363 0.000
T88.2 Shock due to anaesthesia
0.637 0.363 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.637 0.363 0.000
T88.0 Infection following immunisation
0.637 0.363 0.000
I65.2 Occlusion and stenosis of carotid artery
0.637 0.363 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.636 0.364 0.000
C15 Malignant neoplasm of oesophagus
0.636 0.364 0.000
M05-M14 Inflammatory polyarthropathies
0.636 0.364 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.635 0.364 0.000
Y40 Systemic antibiotics
0.635 0.365 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.634 0.365 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.634 0.365 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.634 0.365 0.000
Z13.5 Special screening examination for eye and ear disorders
0.634 0.365 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.634 0.365 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.634 0.365 0.000
Z13.2 Special screening examination for nutritional disorders
0.634 0.365 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.634 0.366 0.000
M75.4 Impingement syndrome of shoulder
0.634 0.366 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.634 0.366 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.634 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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