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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116996274
log Bayes Factor = 16.8749
Chromosome 17   position 72,204,105  (GRCh37) Explore rs116996274 on Ensembl!
Variant rs116996274 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N40-N51 Diseases of male genital organs
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.992 0.008 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
L60-L75 Disorders of skin appendages
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
N50 Other disorders of male genital organs
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.986 0.014 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.981 0.019 0.000
Chapter II Neoplasms
0.980 0.020 0.000
M45-M49 Spondylopathies
0.980 0.020 0.000
I34 Nonrheumatic mitral valve disorders
0.979 0.021 0.000
M54 Dorsalgia
0.974 0.026 0.000
I60-I69 Cerebrovascular diseases
0.972 0.028 0.000
N50.8 Other specified disorders of male genital organs
0.969 0.031 0.000
M54.5 Low back pain
0.967 0.033 0.000
I47 Paroxysmal tachycardia
0.962 0.038 0.000
M54.56 Low back pain (Lumbar region)
0.958 0.042 0.000
N41 Inflammatory diseases of prostate
0.955 0.045 0.000
I34.0 Mitral (valve) insufficiency
0.953 0.047 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.950 0.050 0.000
S60-S69 Injuries to the wrist and hand
0.946 0.054 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.945 0.055 0.000
Chapter VII Diseases of the eye and adnexa
0.943 0.057 0.000
H53-H54 Visual disturbances and blindness
0.941 0.059 0.000
H53 Visual disturbances
0.940 0.060 0.000
L72.0 Epidermal cyst
0.939 0.061 0.000
N60-N64 Disorders of breast
0.938 0.062 0.000
I47.1 Supraventricular tachycardia
0.936 0.064 0.000
I51 Complications and ill-defined descriptions of heart disease
0.935 0.065 0.000
N48 Other disorders of penis
0.934 0.066 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.933 0.067 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.932 0.068 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.931 0.069 0.000
I63 Cerebral infarction
0.930 0.070 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.928 0.072 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.928 0.072 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.927 0.073 0.000
G90-G99 Other disorders of the nervous system
0.926 0.074 0.000
I50 Heart failure
0.924 0.076 0.000
H53.9 Visual disturbance, unspecified
0.923 0.077 0.000
L72.1 Trichilemmal cyst
0.922 0.078 0.000
G40-G47 Episodic and paroxysmal disorders
0.918 0.082 0.000
F30-F39 Mood [affective] disorders
0.916 0.084 0.000
C64-C68 Malignant neoplasms of urinary tract
0.910 0.090 0.000
M48 Other spondylopathies
0.909 0.091 0.000
N41.1 Chronic prostatitis
0.904 0.096 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.904 0.096 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.900 0.100 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.899 0.101 0.000
S00-S09 Injuries to the head
0.896 0.104 0.000
N10-N16 Renal tubulo-interstitial diseases
0.891 0.109 0.000
G93 Other disorders of brain
0.890 0.110 0.000
I63.9 Cerebral infarction, unspecified
0.884 0.116 0.000
H53.1 Subjective visual disturbances
0.884 0.116 0.000
C79 Secondary malignant neoplasm of other sites
0.880 0.120 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.878 0.122 0.000
Y40 Systemic antibiotics
0.878 0.122 0.000
I51.8 Other ill-defined heart diseases
0.877 0.123 0.000
F32 Depressive episode
0.875 0.125 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.871 0.129 0.000
M47 Spondylosis
0.870 0.130 0.000
I50.1 Left ventricular failure
0.870 0.130 0.000
M50 Cervical disk disorders
0.868 0.132 0.000
M86-M90 Other osteopathies
0.865 0.135 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.865 0.135 0.000
M46 Other inflammatory spondylopathies
0.863 0.137 0.000
Chapter VIII Diseases of the ear and mastoid process
0.862 0.138 0.000
M48.0 Spinal stenosis
0.858 0.142 0.000
M54.57 Low back pain (Lumbosacral region)
0.857 0.143 0.000
N63 Unspecified lump in breast
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
N41.0 Acute prostatitis
0.849 0.151 0.000
N60 Benign mammary dysplasia
0.849 0.151 0.000
G47 Sleep disorders
0.848 0.152 0.000
I74 Arterial embolism and thrombosis
0.845 0.155 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.843 0.157 0.000
W00-W19 Falls
0.842 0.158 0.000
I34.1 Mitral (valve) prolapse
0.841 0.159 0.000
N30-N39 Other diseases of urinary system
0.841 0.159 0.000
L71 Rosacea
0.841 0.159 0.000
F32.9 Depressive episode, unspecified
0.836 0.164 0.000
H53.4 Visual field defects
0.834 0.166 0.000
C67 Malignant neoplasm of bladder
0.833 0.167 0.000
L60 Nail disorders
0.831 0.169 0.000
I62 Other nontraumatic intracranial haemorrhage
0.830 0.170 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.830 0.170 0.000
X60-X84 Intentional self-harm
0.829 0.170 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.829 0.171 0.000
G30-G32 Other degenerative diseases of the nervous system
0.825 0.175 0.000
M48.06 Spinal stenosis (Lumbar region)
0.824 0.176 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.822 0.178 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.822 0.178 0.000
W50-W64 Exposure to animate mechanical forces
0.822 0.178 0.000
M91-M94 Chondropathies
0.822 0.178 0.000
T43.2 Other and unspecified antidepressants
0.818 0.182 0.000
N45 Orchitis and epididymitis
0.814 0.186 0.000
N48.8 Other specified disorders of penis
0.814 0.186 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.813 0.187 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.813 0.187 0.000
Y40.9 Systemic antibiotic, unspecified
0.806 0.194 0.000
E10-E14 Diabetes mellitus
0.806 0.194 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.805 0.195 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.805 0.195 0.000
C73 Malignant neoplasm of thyroid gland
0.805 0.195 0.000
H65-H75 Diseases of middle ear and mastoid
0.803 0.197 0.000
I78 Diseases of capillaries
0.801 0.199 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.800 0.200 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.800 0.200 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.799 0.201 0.000
G51 Facial nerve disorders
0.798 0.202 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.797 0.203 0.000
S62 Fracture at wrist and hand level
0.797 0.203 0.000
N43 Hydrocele and spermatocele
0.795 0.205 0.000
S06 Intracranial injury
0.795 0.205 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.794 0.206 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.794 0.206 0.000
N50.1 Vascular disorders of male genital organs
0.793 0.207 0.000
N48.2 Other inflammatory disorders of penis
0.792 0.208 0.000
G50 Disorders of trigeminal nerve
0.790 0.210 0.000
I45 Other conduction disorders
0.790 0.210 0.000
T82.3 Mechanical complication of other vascular grafts
0.790 0.210 0.000
S64 Injury of nerves at wrist and hand level
0.789 0.211 0.000
L40-L45 Papulosquamous disorders
0.789 0.211 0.000
N50.0 Atrophy of testis
0.789 0.211 0.000
I74.5 Embolism and thrombosis of iliac artery
0.788 0.212 0.000
N32 Other disorders of bladder
0.787 0.213 0.000
I05-I09 Chronic rheumatic heart diseases
0.787 0.213 0.000
C80 Malignant neoplasm without specification of site
0.785 0.215 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.785 0.215 0.000
I61 Intracerebral haemorrhage
0.784 0.216 0.000
M47.9 Spondylosis, unspecified
0.784 0.216 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.780 0.220 0.000
G43 Migraine
0.779 0.221 0.000
F41 Other anxiety disorders
0.778 0.222 0.000
F60-F69 Disorders of adult personality and behaviour
0.778 0.222 0.000
M51 Other intervertebral disk disorders
0.777 0.223 0.000
F29 Unspecified nonorganic psychosis
0.776 0.224 0.000
E65-E68 Obesity and other hyperalimentation
0.775 0.225 0.000
S20-S29 Injuries to the thorax
0.775 0.225 0.000
I38 Endocarditis, valve unspecified
0.774 0.226 0.000
M89 Other disorders of bone
0.774 0.226 0.000
I51.9 Heart disease, unspecified
0.771 0.229 0.000
G47.3 Sleep apnoea
0.771 0.229 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.229 0.000
H53.2 Diplopia
0.771 0.229 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.771 0.229 0.000
G54 Nerve root and plexus disorders
0.770 0.230 0.000
S60 Superficial injury of wrist and hand
0.770 0.230 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.769 0.231 0.000
E00-E07 Disorders of thyroid gland
0.769 0.231 0.000
W20-W49 Exposure to inanimate mechanical forces
0.767 0.233 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.767 0.233 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.766 0.234 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.766 0.234 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.765 0.234 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.765 0.235 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.765 0.235 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.765 0.235 0.000
T39.0 Salicylates
0.764 0.236 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.764 0.236 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.764 0.236 0.000
S10-S19 Injuries to the neck
0.763 0.236 0.000
M54.50 Low back pain (Multiple sites in spine)
0.762 0.238 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.761 0.239 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.759 0.241 0.000
G93.6 Cerebral oedema
0.758 0.242 0.000
I69 Sequelae of cerebrovascular disease
0.757 0.243 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.757 0.243 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.757 0.243 0.000
M50.1 Cervical disk disorder with radiculopathy
0.756 0.244 0.000
T39.1 4-Aminophenol derivatives
0.754 0.246 0.000
V20-V29 Motorcycle rider injured in transport accident
0.753 0.247 0.000
N48.0 Leukoplakia of penis
0.751 0.249 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.750 0.250 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.748 0.252 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.748 0.252 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.745 0.255 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.745 0.255 0.000
C79.2 Secondary malignant neoplasm of skin
0.745 0.255 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
G93.9 Disorder of brain, unspecified
0.744 0.256 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.743 0.257 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.741 0.259 0.000
Y40.0 Penicillins
0.740 0.260 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.739 0.261 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.738 0.262 0.000
M54.1 Radiculopathy
0.738 0.262 0.000
E70-E90 Metabolic disorders
0.736 0.264 0.000
X20-X29 Contact with venomous animals and plants
0.735 0.265 0.000
L71.9 Rosacea, unspecified
0.735 0.265 0.000
I70 Atherosclerosis
0.734 0.266 0.000
N32.8 Other specified disorders of bladder
0.733 0.267 0.000
W19 Unspecified fall
0.732 0.268 0.000
F20 Schizophrenia
0.731 0.269 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.731 0.269 0.000
S01 Open wound of head
0.731 0.269 0.000
G40 Epilepsy
0.731 0.269 0.000
D45 Polycythaemia vera
0.731 0.269 0.000
N11 Chronic tubulo-interstitial nephritis
0.729 0.270 0.000
N60.0 Solitary cyst of breast
0.729 0.271 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.728 0.272 0.000
F80-F89 Disorders of psychological development
0.728 0.272 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.728 0.272 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
V80-V89 Other land transport accidents
0.725 0.275 0.000
M54.2 Cervicalgia
0.724 0.276 0.000
C67.6 Ureteric orifice
0.723 0.277 0.000
G35 Multiple sclerosis
0.723 0.277 0.000
E10 Insulin-dependent diabetes mellitus
0.723 0.277 0.000
N48.1 Balanoposthitis
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.721 0.279 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.721 0.279 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.718 0.281 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.718 0.282 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.717 0.283 0.000
N46 Male infertility
0.717 0.283 0.000
N44 Torsion of testis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.716 0.284 0.000
C77.1 Intrathoracic lymph nodes
0.715 0.285 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.715 0.285 0.000
I20-I25 Ischaemic heart diseases
0.715 0.285 0.000
I50.9 Heart failure, unspecified
0.715 0.285 0.000
C67.5 Bladder neck
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.714 0.286 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.713 0.287 0.000
G93.4 Encephalopathy, unspecified
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.713 0.287 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.713 0.287 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.713 0.287 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
T36 Poisoning by systemic antibiotics
0.713 0.287 0.000
G93.8 Other specified disorders of brain
0.712 0.288 0.000
L10-L14 Bullous disorders
0.711 0.289 0.000
C15-C26 Malignant neoplasms of digestive organs
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
I78.1 Naevus, nonneoplastic
0.710 0.290 0.000
L73 Other follicular disorders
0.710 0.290 0.000
N60.1 Diffuse cystic mastopathy
0.709 0.291 0.000
L75 Apocrine sweat disorders
0.709 0.291 0.000
L74 Eccrine sweat disorders
0.709 0.291 0.000
L70 Acne
0.709 0.291 0.000
L68 Hypertrichosis
0.709 0.291 0.000
L67 Hair colour and hair shaft abnormalities
0.709 0.291 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.709 0.291 0.000
L65 Other nonscarring hair loss
0.709 0.291 0.000
L64 Androgenic alopecia
0.709 0.291 0.000
L63 Alopecia areata
0.709 0.291 0.000
L62 Nail disorders in diseases classified elsewhere
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
F43 Reaction to severe stress, and adjustment disorders
0.709 0.291 0.000
M89.9 Disorder of bone, unspecified
0.709 0.291 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.708 0.292 0.000
N50.9 Disorder of male genital organs, unspecified
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.707 0.293 0.000
N30 Cystitis
0.706 0.294 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.705 0.295 0.000
S05 Injury of eye and orbit
0.704 0.296 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.703 0.297 0.000
L72.2 Steatocystoma multiplex
0.703 0.297 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.703 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.297 0.000
M49 Spondylopathies in diseases classified elsewhere
0.703 0.297 0.000
V10-V19 Pedal cyclist injured in transport accident
0.702 0.298 0.000
N32.3 Diverticulum of bladder
0.702 0.298 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.702 0.298 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.702 0.298 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.702 0.298 0.000
G93.0 Cerebral cysts
0.702 0.298 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.701 0.299 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.700 0.300 0.000
H65 Nonsuppurative otitis media
0.698 0.302 0.000
I47.2 Ventricular tachycardia
0.698 0.302 0.000
M54.8 Other dorsalgia
0.698 0.302 0.000
M54.6 Pain in thoracic spine
0.698 0.302 0.000
M54.0 Panniculitis affecting regions of neck and back
0.698 0.302 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.698 0.302 0.000
T82.1 Mechanical complication of cardiac electronic device
0.697 0.303 0.000
G58 Other mononeuropathies
0.697 0.303 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.697 0.303 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.697 0.303 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.696 0.304 0.000
M94 Other disorders of cartilage
0.695 0.304 0.000
L60.0 Ingrowing nail
0.695 0.305 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.695 0.305 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.695 0.305 0.000
S70-S79 Injuries to the hip and thigh
0.695 0.305 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.694 0.306 0.000
M54.55 Low back pain (Thoracolumbar region)
0.693 0.307 0.000
M54.54 Low back pain-Thoracic
0.693 0.307 0.000
M54.53 Low back pain-Cervicothoracic
0.693 0.307 0.000
M54.52 Low back pain-Cervical
0.693 0.307 0.000
M54.51 Low back pain-Occipit-atl-axl
0.693 0.307 0.000
N48.4 Impotence of organic origin
0.692 0.308 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.692 0.308 0.000
M53 Other dorsopathies, not elsewhere classified
0.692 0.308 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.691 0.309 0.000
S69 Other and unspecified injuries of wrist and hand
0.690 0.310 0.000
T93 Sequelae of injuries of lower limb
0.690 0.310 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.689 0.310 0.000
I47.0 Reentry ventricular arrhythmia
0.689 0.310 0.000
G51.0 Bell's palsy
0.689 0.311 0.000
H66 Suppurative and unspecified otitis media
0.687 0.313 0.000
I60 Subarachnoid haemorrhage
0.687 0.313 0.000
I71 Aortic aneurysm and dissection
0.687 0.313 0.000
M47.2 Other spondylosis with radiculopathy
0.687 0.313 0.000
M54.4 Lumbago with sciatica
0.685 0.315 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.685 0.315 0.000
N41.8 Other inflammatory diseases of prostate
0.685 0.315 0.000
N41.3 Prostatocystitis
0.685 0.315 0.000
N41.2 Abscess of prostate
0.685 0.315 0.000
N99-N99 Other disorders of the genitourinary system
0.684 0.315 0.000
M80-M85 Disorders of bone density and structure
0.683 0.317 0.000
H55-H59 Other disorders of eye and adnexa
0.683 0.317 0.000
F25 Schizoaffective disorders
0.682 0.318 0.000
C79.6 Secondary malignant neoplasm of ovary
0.682 0.318 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.681 0.319 0.000
G52 Disorders of other cranial nerves
0.681 0.319 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.681 0.319 0.000
N61 Inflammatory disorders of breast
0.680 0.320 0.000
C80.9 Malignant neoplasm, unspecified
0.680 0.320 0.000
S65 Injury of blood vessels at wrist and hand level
0.678 0.322 0.000
I33 Acute and subacute endocarditis
0.678 0.322 0.000
L40 Psoriasis
0.678 0.322 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.677 0.323 0.000
L50-L54 Urticaria and erythema
0.677 0.323 0.000
I72 Other aneurysm
0.677 0.323 0.000
S64.4 Injury of digital nerve of other finger
0.676 0.324 0.000
G50.0 Trigeminal neuralgia
0.676 0.324 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.675 0.325 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.675 0.325 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.675 0.325 0.000
C34 Malignant neoplasm of bronchus and lung
0.675 0.325 0.000
F33 Recurrent depressive disorder
0.675 0.325 0.000
H53.6 Night blindness
0.674 0.326 0.000
H53.5 Colour vision deficiencies
0.674 0.326 0.000
H53.3 Other disorders of binocular vision
0.674 0.326 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.673 0.327 0.000
Y57 Other and unspecified drugs and medicaments
0.673 0.327 0.000
S61 Open wound of wrist and hand
0.671 0.329 0.000
H10-H13 Disorders of conjunctiva
0.671 0.329 0.000
M05-M14 Inflammatory polyarthropathies
0.671 0.329 0.000
I51.6 Cardiovascular disease, unspecified
0.671 0.329 0.000
I51.5 Myocardial degeneration
0.671 0.329 0.000
I51.4 Myocarditis, unspecified
0.671 0.329 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.671 0.329 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.671 0.329 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.671 0.329 0.000
I51.0 Cardiac septal defect, acquired
0.671 0.329 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.670 0.330 0.000
N48.9 Disorder of penis, unspecified
0.670 0.330 0.000
N48.5 Ulcer of penis
0.670 0.330 0.000
N48.3 Priapism
0.670 0.330 0.000
M45 Ankylosing spondylitis
0.669 0.330 0.000
Y59 Other and unspecified vaccines and biological substances
0.669 0.331 0.000
Y58 Bacterial vaccines
0.669 0.331 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.669 0.331 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.669 0.331 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.669 0.331 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.669 0.331 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.669 0.331 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.669 0.331 0.000
Y48 Anaesthetics and therapeutic gases
0.669 0.331 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.669 0.331 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.669 0.331 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.669 0.331 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.669 0.331 0.000
N30.2 Other chronic cystitis
0.669 0.331 0.000
C71 Malignant neoplasm of brain
0.669 0.331 0.000
T43.9 Psychotropic drug, unspecified
0.668 0.332 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
T43.6 Psychostimulants with abuse potential
0.668 0.332 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.668 0.332 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.668 0.332 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.668 0.332 0.000
I63.8 Other cerebral infarction
0.668 0.332 0.000
F22 Persistent delusional disorders
0.668 0.332 0.000
E40-E46 Malnutrition
0.668 0.332 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.667 0.333 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.667 0.333 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.667 0.333 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.667 0.333 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.667 0.333 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.665 0.334 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.665 0.334 0.000
T39.4 Antirheumatics, not elsewhere classified
0.665 0.334 0.000
T39.2 Pyrazolone derivatives
0.665 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.665 0.335 0.000
W55 Bitten or struck by other mammals
0.664 0.336 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.664 0.336 0.000
G96 Other disorders of central nervous system
0.664 0.336 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.664 0.336 0.000
G90 Disorders of autonomic nervous system
0.664 0.336 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.664 0.336 0.000
G92 Toxic encephalopathy
0.664 0.336 0.000
I45.5 Other specified heart block
0.664 0.336 0.000
E66 Obesity
0.664 0.336 0.000
T79-T79 Certain early complications of trauma
0.664 0.336 0.000
N13 Obstructive and reflux uropathy
0.664 0.336 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.663 0.337 0.000
E89.0 Postprocedural hypothyroidism
0.663 0.337 0.000
N60.2 Fibroadenosis of breast
0.662 0.338 0.000
Chapter XXI Factors influencing health status and contact with health services
0.662 0.338 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.662 0.338 0.000
L03 Cellulitis
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.661 0.339 0.000
E13 Other specified diabetes mellitus
0.660 0.340 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.660 0.340 0.000
N36 Other disorders of urethra
0.659 0.341 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.658 0.342 0.000
G41 Status epilepticus
0.658 0.342 0.000
S00 Superficial injury of head
0.658 0.342 0.000
Q60-Q64 Congenital malformations of the urinary system
0.657 0.343 0.000
F41.2 Mixed anxiety and depressive disorder
0.657 0.343 0.000
F38 Other mood [affective] disorders
0.656 0.343 0.000
F34 Persistent mood [affective] disorders
0.656 0.343 0.000
F30 Manic episode
0.656 0.343 0.000
F39 Unspecified mood [affective] disorder
0.656 0.343 0.000
G93.3 Postviral fatigue syndrome
0.656 0.344 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.656 0.344 0.000
E04 Other non-toxic goitre
0.655 0.345 0.000
S40-S49 Injuries to the shoulder and upper arm
0.654 0.346 0.000
Y52 Agents primarily affecting the cardiovascular system
0.653 0.347 0.000
Q80-Q89 Other congenital malformations
0.653 0.347 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.653 0.347 0.000
C66 Malignant neoplasm of ureter
0.653 0.347 0.000
C65 Malignant neoplasm of renal pelvis
0.653 0.347 0.000
M48.9 Spondylopathy, unspecified
0.652 0.348 0.000
M48.8 Other specified spondylopathies
0.652 0.348 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.652 0.348 0.000
M48.4 Fatigue fracture of vertebra
0.652 0.348 0.000
M48.3 Traumatic spondylopathy
0.652 0.348 0.000
M48.2 Kissing spine
0.652 0.348 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.652 0.348 0.000
Y44 Agents primarily affecting blood constituents
0.649 0.351 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.649 0.351 0.000
M50.2 Other cervical disk displacement
0.649 0.351 0.000
N43.3 Hydrocele, unspecified
0.649 0.351 0.000
E83 Disorders of mineral metabolism
0.648 0.352 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.648 0.352 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.648 0.352 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.648 0.352 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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