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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117046754
log Bayes Factor = 24.4021
Chromosome 11   position 77,973,378  (GRCh37) Explore rs117046754 on Ensembl!
Variant rs117046754 is part of Cluster X0037

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.999 0.001 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.997 0.003 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.992 0.008 0.000
Z90.1 Acquired absence of breast(s)
0.991 0.009 0.000
Z86 Personal history of certain other diseases
0.990 0.010 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.984 0.016 0.000
K80 Cholelithiasis
0.982 0.018 0.000
F30-F39 Mood [affective] disorders
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
Z86.0 Personal history of other neoplasms
0.981 0.019 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.977 0.023 0.000
K55-K64 Other diseases of intestines
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
C50-C50 Malignant neoplasm of breast
0.973 0.027 0.000
M05-M14 Inflammatory polyarthropathies
0.970 0.030 0.000
F32 Depressive episode
0.970 0.030 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.968 0.032 0.000
Chapter XIV Diseases of the genitourinary system
0.961 0.039 0.000
C79 Secondary malignant neoplasm of other sites
0.961 0.039 0.000
I25.1 Atherosclerotic heart disease
0.957 0.043 0.000
C50 Malignant neoplasm of breast
0.953 0.047 0.000
C50.4 Upper-outer quadrant of breast
0.952 0.048 0.000
Z88.2 Personal history of allergy to sulphonamides
0.952 0.048 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.949 0.051 0.000
Z95.0 Presence of cardiac pacemaker
0.949 0.051 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.947 0.053 0.000
I25.2 Old myocardial infarction
0.946 0.054 0.000
D10-D36 Benign neoplasms
0.945 0.055 0.000
M13 Other arthritis
0.945 0.055 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.944 0.056 0.000
Z86.7 Personal history of diseases of the circulatory system
0.943 0.057 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.942 0.058 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.938 0.062 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.937 0.063 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.929 0.071 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.929 0.071 0.000
D12.5 Sigmoid colon
0.928 0.072 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.928 0.072 0.000
M13.9 Arthritis, unspecified
0.926 0.074 0.000
K59 Other functional intestinal disorders
0.925 0.075 0.000
H55-H59 Other disorders of eye and adnexa
0.924 0.076 0.000
E78.5 Hyperlipidaemia, unspecified
0.924 0.076 0.000
E86 Volume depletion
0.920 0.080 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.913 0.087 0.000
C34 Malignant neoplasm of bronchus and lung
0.913 0.087 0.000
S00-S09 Injuries to the head
0.912 0.088 0.000
I24 Other acute ischaemic heart diseases
0.910 0.090 0.000
F32.9 Depressive episode, unspecified
0.906 0.094 0.000
K90-K93 Other diseases of the digestive system
0.903 0.097 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.903 0.097 0.000
Z95.1 Presence of aortocoronary bypass graft
0.900 0.100 0.000
K59.0 Constipation
0.899 0.101 0.000
K22 Other diseases of oesophagus
0.898 0.102 0.000
I25.5 Ischaemic cardiomyopathy
0.896 0.104 0.000
S40-S49 Injuries to the shoulder and upper arm
0.895 0.105 0.000
Z90.7 Acquired absence of genital organ(s)
0.892 0.108 0.000
M06 Other rheumatoid arthritis
0.890 0.110 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.889 0.111 0.000
Z95.2 Presence of prosthetic heart valve
0.887 0.113 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.885 0.115 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.884 0.116 0.000
K31 Other diseases of stomach and duodenum
0.883 0.117 0.000
S00 Superficial injury of head
0.883 0.117 0.000
D12.6 Colon, unspecified
0.883 0.117 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.881 0.119 0.000
K08 Other disorders of teeth and supporting structures
0.880 0.120 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.877 0.123 0.000
G90-G99 Other disorders of the nervous system
0.876 0.124 0.000
E78.0 Pure hypercholesterolaemia
0.875 0.125 0.000
H30-H36 Disorders of choroid and retina
0.875 0.125 0.000
I30-I52 Other forms of heart disease
0.874 0.126 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.873 0.127 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.871 0.129 0.000
T66-T78 Other and unspecified effects of external causes
0.870 0.130 0.000
N30-N39 Other diseases of urinary system
0.867 0.133 0.000
D23 Other benign neoplasms of skin
0.866 0.134 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.864 0.136 0.000
D00-D09 In situ neoplasms
0.862 0.138 0.000
K57 Diverticular disease of intestine
0.861 0.139 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.860 0.140 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.860 0.140 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.859 0.141 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.857 0.143 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.856 0.144 0.000
N32 Other disorders of bladder
0.854 0.146 0.000
C34.1 Upper lobe, bronchus or lung
0.852 0.148 0.000
M50-M54 Other dorsopathies
0.852 0.148 0.000
K31.7 Polyp of stomach and duodenum
0.852 0.148 0.000
I95 Hypotension
0.852 0.148 0.000
G56 Mononeuropathies of upper limb
0.850 0.150 0.000
I05-I09 Chronic rheumatic heart diseases
0.849 0.151 0.000
E20-E35 Disorders of other endocrine glands
0.848 0.152 0.000
H40-H42 Glaucoma
0.848 0.152 0.000
N32.8 Other specified disorders of bladder
0.847 0.153 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.846 0.154 0.000
S70-S79 Injuries to the hip and thigh
0.846 0.154 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.845 0.155 0.000
F33 Recurrent depressive disorder
0.842 0.158 0.000
Chapter VIII Diseases of the ear and mastoid process
0.841 0.159 0.000
Z98 Other postsurgical states
0.840 0.160 0.000
K35-K38 Diseases of appendix
0.839 0.161 0.000
Z88.6 Personal history of allergy to analgesic agent
0.839 0.161 0.000
K83 Other diseases of biliary tract
0.838 0.162 0.000
K63 Other diseases of intestine
0.837 0.163 0.000
N20-N23 Urolithiasis
0.836 0.164 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.835 0.165 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.835 0.165 0.000
M80-M85 Disorders of bone density and structure
0.834 0.166 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.833 0.167 0.000
C78.0 Secondary malignant neoplasm of lung
0.831 0.169 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.828 0.172 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.824 0.176 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.821 0.179 0.000
E87.2 Acidosis
0.820 0.180 0.000
M86-M90 Other osteopathies
0.817 0.183 0.000
E87.6 Hypokalaemia
0.816 0.184 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.815 0.185 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.815 0.185 0.000
N25-N29 Other disorders of kidney and ureter
0.813 0.187 0.000
S00.9 Superficial injury of head, part unspecified
0.813 0.187 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.812 0.188 0.000
K22.8 Other specified diseases of oesophagus
0.808 0.192 0.000
K13 Other diseases of lip and oral mucosa
0.808 0.192 0.000
Z91.5 Personal history of self-harm
0.808 0.192 0.000
H33 Retinal detachments and breaks
0.807 0.193 0.000
D12.4 Descending colon
0.807 0.193 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.807 0.193 0.000
Z96 Presence of other functional implants
0.805 0.195 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.803 0.197 0.000
I95.1 Orthostatic hypotension
0.803 0.197 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.802 0.198 0.000
G56.0 Carpal tunnel syndrome
0.801 0.199 0.000
K92 Other diseases of digestive system
0.800 0.200 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.799 0.201 0.000
K22.2 Oesophageal obstruction
0.799 0.201 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.798 0.202 0.000
K86 Other diseases of pancreas
0.796 0.203 0.000
C80 Malignant neoplasm without specification of site
0.795 0.205 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.794 0.206 0.000
K55 Vascular disorders of intestine
0.793 0.207 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.793 0.207 0.000
H57 Other disorders of eye and adnexa
0.792 0.208 0.000
H55 Nystagmus and other irregular eye movements
0.789 0.211 0.000
K29 Gastritis and duodenitis
0.789 0.211 0.000
M06.9 Rheumatoid arthritis, unspecified
0.788 0.212 0.000
F99-F99 Unspecified mental disorder
0.786 0.214 0.000
Z89 Acquired absence of limb
0.786 0.214 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.785 0.215 0.000
F41 Other anxiety disorders
0.783 0.217 0.000
N81 Female genital prolapse
0.782 0.218 0.000
M45-M49 Spondylopathies
0.780 0.220 0.000
D23.1 Skin of eyelid, including canthus
0.780 0.220 0.000
T78 Adverse effects, not elsewhere classified
0.777 0.223 0.000
K22.4 Dyskinesia of oesophagus
0.777 0.223 0.000
N94.1 Dyspareunia
0.777 0.223 0.000
H10-H13 Disorders of conjunctiva
0.777 0.223 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.775 0.225 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.774 0.226 0.000
K56.6 Other and unspecified intestinal obstruction
0.774 0.226 0.000
C78.7 Secondary malignant neoplasm of liver
0.773 0.227 0.000
Z96.8 Presence of other specified functional implants
0.773 0.227 0.000
N32.3 Diverticulum of bladder
0.772 0.228 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.772 0.228 0.000
H65-H75 Diseases of middle ear and mastoid
0.772 0.228 0.000
C34.9 Bronchus or lung, unspecified
0.772 0.228 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.770 0.230 0.000
I45 Other conduction disorders
0.770 0.230 0.000
Z91.6 Personal history of other physical trauma
0.769 0.231 0.000
T39.0 Salicylates
0.769 0.231 0.000
Z95.3 Presence of xenogenic heart valve
0.768 0.232 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.765 0.235 0.000
N88 Other noninflammatory disorders of cervix uteri
0.765 0.235 0.000
D60-D64 Aplastic and other anaemias
0.765 0.235 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.765 0.235 0.000
E73 Lactose intolerance
0.763 0.237 0.000
F32.1 Moderate depressive episode
0.763 0.237 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.761 0.238 0.000
K11 Diseases of salivary glands
0.761 0.239 0.000
Z88.5 Personal history of allergy to narcotic agent
0.761 0.239 0.000
T51 Toxic effect of alcohol
0.761 0.239 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.760 0.240 0.000
I42 Cardiomyopathy
0.760 0.240 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.760 0.240 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.759 0.241 0.000
R94 Abnormal results of function studies
0.759 0.241 0.000
F32.0 Mild depressive episode
0.757 0.243 0.000
I10-I15 Hypertensive diseases
0.757 0.243 0.000
S50-S59 Injuries to the elbow and forearm
0.757 0.243 0.000
K07 Dentofacial anomalies [including malocclusion]
0.756 0.244 0.000
Z81 Family history of mental and behavioural disorders
0.755 0.245 0.000
K26 Duodenal ulcer
0.754 0.246 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.754 0.246 0.000
M20-M25 Other joint disorders
0.754 0.246 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.754 0.246 0.000
H33.2 Serous retinal detachment
0.754 0.246 0.000
K70-K77 Diseases of liver
0.753 0.247 0.000
C78.2 Secondary malignant neoplasm of pleura
0.753 0.247 0.000
K62 Other diseases of anus and rectum
0.753 0.247 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.753 0.247 0.000
H40 Glaucoma
0.753 0.247 0.000
K63.9 Disease of intestine, unspecified
0.752 0.248 0.000
I60-I69 Cerebrovascular diseases
0.752 0.248 0.000
E78.2 Mixed hyperlipidaemia
0.752 0.248 0.000
Z88.0 Personal history of allergy to penicillin
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.751 0.249 0.000
I21 Acute myocardial infarction
0.750 0.250 0.000
Z90.0 Acquired absence of part of head and neck
0.749 0.251 0.000
M06.0 Seronegative rheumatoid arthritis
0.748 0.252 0.000
Z85 Personal history of malignant neoplasm
0.748 0.252 0.000
S40 Superficial injury of shoulder and upper arm
0.747 0.253 0.000
D12.3 Transverse colon
0.747 0.253 0.000
M54 Dorsalgia
0.747 0.253 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.746 0.254 0.000
K90 Intestinal malabsorption
0.746 0.254 0.000
F41.9 Anxiety disorder, unspecified
0.743 0.257 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.742 0.258 0.000
K35 Acute appendicitis
0.742 0.258 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.742 0.258 0.000
D23.4 Skin of scalp and neck
0.741 0.259 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.741 0.259 0.000
K56.4 Other impaction of intestine
0.740 0.260 0.000
N10-N16 Renal tubulo-interstitial diseases
0.740 0.260 0.000
T39.1 4-Aminophenol derivatives
0.739 0.261 0.000
N60-N64 Disorders of breast
0.739 0.261 0.000
Chapter XX External causes of morbidity and mortality
0.737 0.263 0.000
D12.2 Ascending colon
0.737 0.263 0.000
D03 Melanoma in situ
0.737 0.263 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.736 0.264 0.000
H43-H45 Disorders of vitreous body and globe
0.736 0.264 0.000
K80.4 Calculus of bile duct with cholecystitis
0.735 0.265 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.735 0.265 0.000
H72 Perforation of tympanic membrane
0.734 0.266 0.000
K83.1 Obstruction of bile duct
0.733 0.267 0.000
Z83 Family history of other specific disorders
0.733 0.267 0.000
Z90.2 Acquired absence of lung [part of]
0.733 0.267 0.000
Chapter XXII Codes for special purposes
0.732 0.267 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.731 0.269 0.000
S42 Fracture of shoulder and upper arm
0.730 0.270 0.000
K00 Disorders of tooth development and eruption
0.729 0.270 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.270 0.000
G93 Other disorders of brain
0.729 0.271 0.000
K50-K52 Noninfective enteritis and colitis
0.729 0.271 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.728 0.272 0.000
D04 Carcinoma in situ of skin
0.728 0.272 0.000
F43 Reaction to severe stress, and adjustment disorders
0.728 0.272 0.000
G30-G32 Other degenerative diseases of the nervous system
0.727 0.273 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.726 0.274 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.725 0.275 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.725 0.275 0.000
I24.8 Other forms of acute ischaemic heart disease
0.724 0.276 0.000
E88 Other metabolic disorders
0.724 0.276 0.000
K85 Acute pancreatitis
0.723 0.277 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.723 0.277 0.000
G12 Spinal muscular atrophy and related syndromes
0.722 0.278 0.000
G20-G26 Extrapyramidal and movement disorders
0.722 0.278 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.721 0.279 0.000
C50.1 Central portion of breast
0.720 0.280 0.000
D34 Benign neoplasm of thyroid gland
0.719 0.281 0.000
F33.9 Recurrent depressive disorder, unspecified
0.719 0.281 0.000
I51 Complications and ill-defined descriptions of heart disease
0.718 0.282 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.718 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M65-M68 Disorders of synovium and tendon
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
I49 Other cardiac arrhythmias
0.716 0.284 0.000
K31.4 Gastric diverticulum
0.716 0.284 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.715 0.285 0.000
K59.9 Functional intestinal disorder, unspecified
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.715 0.285 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.715 0.285 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.715 0.285 0.000
F60-F69 Disorders of adult personality and behaviour
0.715 0.285 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.714 0.285 0.000
M13.98 Arthritis, unspecified (Other)
0.714 0.286 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.714 0.286 0.000
Z94 Transplanted organ and tissue status
0.713 0.287 0.000
N87 Dysplasia of cervix uteri
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.287 0.000
F80-F89 Disorders of psychological development
0.712 0.287 0.000
F70-F79 Mental retardation
0.712 0.287 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.712 0.287 0.000
N88.2 Stricture and stenosis of cervix uteri
0.712 0.288 0.000
N36 Other disorders of urethra
0.712 0.288 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.711 0.288 0.000
C34.3 Lower lobe, bronchus or lung
0.711 0.289 0.000
S60-S69 Injuries to the wrist and hand
0.711 0.289 0.000
D11 Benign neoplasm of major salivary glands
0.711 0.289 0.000
S00.1 Contusion of eyelid and periocular area
0.710 0.289 0.000
I08 Multiple valve diseases
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.710 0.290 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.710 0.290 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
S00.8 Superficial injury of other parts of head
0.709 0.291 0.000
M13.93 Arthritis, unspecified (Forearm)
0.707 0.293 0.000
N23 Unspecified renal colic
0.707 0.293 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.707 0.293 0.000
Z72 Problems related to lifestyle
0.707 0.293 0.000
I44 Atrioventricular and left bundle-branch block
0.707 0.293 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.706 0.294 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.706 0.294 0.000
K27 Peptic ulcer, site unspecified
0.706 0.294 0.000
E85 Amyloidosis
0.705 0.295 0.000
E84 Cystic fibrosis
0.705 0.295 0.000
E79 Disorders of purine and pyrimidine metabolism
0.705 0.295 0.000
E77 Disorders of glycoprotein metabolism
0.705 0.295 0.000
E76 Disorders of glycosaminoglycan metabolism
0.705 0.295 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.705 0.295 0.000
E74 Other disorders of carbohydrate metabolism
0.705 0.295 0.000
E72 Other disorders of amino-acid metabolism
0.705 0.295 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.705 0.295 0.000
E70 Disorders of aromatic amino-acid metabolism
0.705 0.295 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.705 0.295 0.000
K80.3 Calculus of bile duct with cholangitis
0.704 0.296 0.000
K80.8 Other cholelithiasis
0.704 0.296 0.000
F38 Other mood [affective] disorders
0.704 0.296 0.000
F34 Persistent mood [affective] disorders
0.704 0.296 0.000
F30 Manic episode
0.704 0.296 0.000
F39 Unspecified mood [affective] disorder
0.704 0.296 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.704 0.296 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.704 0.296 0.000
S41 Open wound of shoulder and upper arm
0.702 0.298 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.701 0.299 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.701 0.299 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.701 0.299 0.000
D12.7 Rectosigmoid junction
0.700 0.300 0.000
N00-N08 Glomerular diseases
0.699 0.301 0.000
N81.4 Uterovaginal prolapse, unspecified
0.699 0.301 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.699 0.301 0.000
K10 Other diseases of jaws
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
S00.0 Superficial injury of scalp
0.696 0.304 0.000
M14 Arthropathies in other diseases classified elsewhere
0.695 0.304 0.000
M12 Other specific arthropathies
0.695 0.304 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.695 0.304 0.000
M08 Juvenile arthritis
0.695 0.304 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.695 0.305 0.000
F32.8 Other depressive episodes
0.695 0.305 0.000
R12 Heartburn
0.695 0.305 0.000
E78.8 Other disorders of lipoprotein metabolism
0.694 0.306 0.000
E78.6 Lipoprotein deficiency
0.694 0.306 0.000
E78.4 Other hyperlipidaemia
0.694 0.306 0.000
E78.3 Hyperchylomicronaemia
0.694 0.306 0.000
E78.1 Pure hyperglyceridaemia
0.694 0.306 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.694 0.306 0.000
D27 Benign neoplasm of ovary
0.694 0.306 0.000
Z98.0 Intestinal bypass and anastomosis status
0.694 0.306 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.694 0.306 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.693 0.307 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.693 0.307 0.000
G56.2 Lesion of ulnar nerve
0.693 0.307 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.693 0.307 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.691 0.309 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.691 0.309 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.690 0.310 0.000
D80-D89 Certain disorders involving the immune mechanism
0.689 0.311 0.000
K22.9 Disease of oesophagus, unspecified
0.689 0.311 0.000
C79.6 Secondary malignant neoplasm of ovary
0.689 0.311 0.000
C79.2 Secondary malignant neoplasm of skin
0.689 0.311 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.689 0.311 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.689 0.311 0.000
K09 Cysts of oral region, not elsewhere classified
0.688 0.312 0.000
K62.1 Rectal polyp
0.688 0.312 0.000
S79 Other and unspecified injuries of hip and thigh
0.688 0.312 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.688 0.312 0.000
M54.5 Low back pain
0.688 0.312 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.687 0.313 0.000
M13.0 Polyarthritis, unspecified
0.687 0.313 0.000
T88.4 Failed or difficult intubation
0.687 0.313 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.687 0.313 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.686 0.314 0.000
K56.0 Paralytic ileus
0.686 0.314 0.000
M47 Spondylosis
0.686 0.314 0.000
E28 Ovarian dysfunction
0.686 0.314 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.685 0.315 0.000
M80 Osteoporosis with pathological fracture
0.685 0.315 0.000
T43.2 Other and unspecified antidepressants
0.684 0.316 0.000
S70 Superficial injury of hip and thigh
0.684 0.316 0.000
C50.6 Axillary tail of breast
0.684 0.316 0.000
C50.0 Nipple and areola
0.684 0.316 0.000
M05 Seropositive rheumatoid arthritis
0.683 0.317 0.000
D26 Other benign neoplasms of uterus
0.682 0.317 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.682 0.318 0.000
D23.3 Skin of other and unspecified parts of face
0.682 0.318 0.000
D36 Benign neoplasm of other and unspecified sites
0.682 0.318 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.682 0.318 0.000
N21 Calculus of lower urinary tract
0.681 0.319 0.000
C50.8 Overlapping lesion of breast
0.681 0.319 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.680 0.319 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.680 0.319 0.000
C32 Malignant neoplasm of larynx
0.680 0.319 0.000
C31 Malignant neoplasm of accessory sinuses
0.680 0.319 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.680 0.319 0.000
C37 Malignant neoplasm of thymus
0.680 0.319 0.000
C33 Malignant neoplasm of trachea
0.680 0.319 0.000
Z72.0 Tobacco use
0.680 0.320 0.000
Z90.5 Acquired absence of kidney
0.679 0.320 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.679 0.321 0.000
D64 Other anaemias
0.679 0.321 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.679 0.321 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.679 0.321 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.679 0.321 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.321 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.679 0.321 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.679 0.321 0.000
T36 Poisoning by systemic antibiotics
0.679 0.321 0.000
K62.3 Rectal prolapse
0.679 0.321 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.678 0.322 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.678 0.322 0.000
M50 Cervical disk disorders
0.678 0.322 0.000
D31 Benign neoplasm of eye and adnexa
0.678 0.322 0.000
D30 Benign neoplasm of urinary organs
0.678 0.322 0.000
D29 Benign neoplasm of male genital organs
0.678 0.322 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.678 0.322 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.678 0.322 0.000
D19 Benign neoplasm of mesothelial tissue
0.678 0.322 0.000
D16 Benign neoplasm of bone and articular cartilage
0.678 0.322 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.678 0.322 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.678 0.322 0.000
M13.8 Other specified arthritis
0.677 0.323 0.000
M13.1 Monoarthritis, not elsewhere classified
0.677 0.323 0.000
Z22 Carrier of infectious disease
0.677 0.323 0.000
K03 Other diseases of hard tissues of teeth
0.677 0.323 0.000
Z95.4 Presence of other heart-valve replacement
0.677 0.323 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.677 0.323 0.000
D12.9 Anus and anal canal
0.676 0.324 0.000
D12.1 Appendix
0.676 0.324 0.000
E23 Hypofunction and other disorders of pituitary gland
0.675 0.325 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.673 0.327 0.000
K08.3 Retained dental root
0.673 0.327 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.673 0.327 0.000
Z91.7 Personal history of female genital mutilation
0.673 0.327 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.673 0.327 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.673 0.327 0.000
Z91.2 Personal history of poor personal hygiene
0.673 0.327 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.672 0.328 0.000
R18 Ascites
0.671 0.329 0.000
I21.4 Acute subendocardial myocardial infarction
0.671 0.329 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.670 0.330 0.000
K12 Stomatitis and related lesions
0.670 0.330 0.000
K31.5 Obstruction of duodenum
0.669 0.331 0.000
G91 Hydrocephalus
0.669 0.331 0.000
T51.0 Ethanol
0.667 0.333 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.666 0.334 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.666 0.334 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.666 0.334 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.666 0.334 0.000
I45.6 Preexcitation syndrome
0.665 0.335 0.000
K28 Gastrojejunal ulcer
0.665 0.335 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.665 0.335 0.000
K04 Diseases of pulp and periapical tissues
0.665 0.335 0.000
I46 Cardiac arrest
0.665 0.335 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.665 0.335 0.000
M11 Other crystal arthropathies
0.664 0.335 0.000
H34 Retinal vascular occlusions
0.664 0.336 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.664 0.336 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.663 0.337 0.000
K29.7 Gastritis, unspecified
0.663 0.337 0.000
K59.4 Anal spasm
0.663 0.337 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.663 0.337 0.000
Z90.3 Acquired absence of part of stomach
0.663 0.337 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.663 0.337 0.000
G56.8 Other mononeuropathies of upper limb
0.662 0.338 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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