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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117096873
log Bayes Factor = 11.0059
Chromosome 16   position 11,386,960  (GRCh37) Explore rs117096873 on Ensembl!
Variant rs117096873 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
J20-J22 Other acute lower respiratory infections
0.996 0.004 0.000
J22 Unspecified acute lower respiratory infection
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
M50-M54 Other dorsopathies
0.983 0.017 0.000
M54 Dorsalgia
0.977 0.023 0.000
Chapter VIII Diseases of the ear and mastoid process
0.976 0.024 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.975 0.025 0.000
J40-J47 Chronic lower respiratory diseases
0.973 0.027 0.000
Chapter II Neoplasms
0.966 0.034 0.000
H65-H75 Diseases of middle ear and mastoid
0.962 0.038 0.000
C64-C68 Malignant neoplasms of urinary tract
0.955 0.045 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.955 0.045 0.000
C67 Malignant neoplasm of bladder
0.952 0.048 0.000
Chapter VII Diseases of the eye and adnexa
0.950 0.050 0.000
J00-J06 Acute upper respiratory infections
0.949 0.051 0.000
M54.9 Dorsalgia, unspecified
0.941 0.059 0.000
J40 Bronchitis, not specified as acute or chronic
0.940 0.060 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.928 0.072 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.927 0.073 0.000
C67.9 Bladder, unspecified
0.926 0.074 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.922 0.078 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.920 0.080 0.000
M70-M79 Other soft tissue disorders
0.918 0.082 0.000
Chapter V Mental and behavioural disorders
0.918 0.082 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.916 0.084 0.000
G81 Hemiplegia
0.910 0.090 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.906 0.094 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.905 0.095 0.000
M45-M49 Spondylopathies
0.905 0.095 0.000
D00-D09 In situ neoplasms
0.899 0.101 0.000
H66 Suppurative and unspecified otitis media
0.899 0.101 0.000
M54.5 Low back pain
0.896 0.104 0.000
Chapter XX External causes of morbidity and mortality
0.895 0.105 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.893 0.107 0.000
B25-B34 Other viral diseases
0.889 0.111 0.000
H30-H36 Disorders of choroid and retina
0.886 0.114 0.000
C67.2 Lateral wall of bladder
0.882 0.118 0.000
G81.9 Hemiplegia, unspecified
0.879 0.121 0.000
J44 Other chronic obstructive pulmonary disease
0.879 0.121 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.875 0.125 0.000
J06.9 Acute upper respiratory infection, unspecified
0.874 0.126 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.873 0.127 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.871 0.129 0.000
B95-B98 Bacterial, viral and other infectious agents
0.867 0.133 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.860 0.140 0.000
M54.59 Low back pain (Site unspecified)
0.859 0.141 0.000
G30-G32 Other degenerative diseases of the nervous system
0.859 0.141 0.000
T40.2 Other opioids
0.858 0.142 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.857 0.143 0.000
J43 Emphysema
0.857 0.143 0.000
S80-S89 Injuries to the knee and lower leg
0.856 0.144 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.853 0.147 0.000
M80-M85 Disorders of bone density and structure
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.851 0.149 0.000
S70-S79 Injuries to the hip and thigh
0.843 0.156 0.000
M20-M25 Other joint disorders
0.842 0.157 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.842 0.158 0.000
Chapter XXII Codes for special purposes
0.842 0.158 0.000
T79-T79 Certain early complications of trauma
0.840 0.160 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.833 0.167 0.000
H66.9 Otitis media, unspecified
0.833 0.167 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.831 0.169 0.000
C60-C63 Malignant neoplasms of male genital organs
0.830 0.170 0.000
M40-M43 Deforming dorsopathies
0.829 0.171 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.829 0.171 0.000
T93 Sequelae of injuries of lower limb
0.823 0.177 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
H70 Mastoiditis and related conditions
0.820 0.180 0.000
B34 Viral infection of unspecified site
0.818 0.182 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.816 0.184 0.000
H72 Perforation of tympanic membrane
0.813 0.187 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.813 0.187 0.000
S50-S59 Injuries to the elbow and forearm
0.809 0.191 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.805 0.195 0.000
S10-S19 Injuries to the neck
0.801 0.199 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.798 0.202 0.000
H35 Other retinal disorders
0.796 0.204 0.000
J00 Acute nasopharyngitis [common cold]
0.794 0.206 0.000
T51 Toxic effect of alcohol
0.794 0.206 0.000
D04 Carcinoma in situ of skin
0.791 0.209 0.000
M54.3 Sciatica
0.791 0.209 0.000
D50-D53 Nutritional anaemias
0.791 0.209 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.791 0.209 0.000
S60-S69 Injuries to the wrist and hand
0.790 0.210 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.786 0.214 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.783 0.217 0.000
T42.4 Benzodiazepines
0.783 0.217 0.000
M91-M94 Chondropathies
0.782 0.218 0.000
H74 Other disorders of middle ear and mastoid
0.782 0.218 0.000
M54.1 Radiculopathy
0.780 0.220 0.000
G82 Paraplegia and tetraplegia
0.779 0.221 0.000
G40-G47 Episodic and paroxysmal disorders
0.777 0.223 0.000
J43.9 Emphysema, unspecified
0.774 0.226 0.000
C67.0 Trigone of bladder
0.774 0.226 0.000
S20-S29 Injuries to the thorax
0.774 0.226 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.772 0.228 0.000
G30 Alzheimer's disease
0.772 0.228 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.771 0.229 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.769 0.231 0.000
M48 Other spondylopathies
0.768 0.232 0.000
B34.9 Viral infection, unspecified
0.768 0.232 0.000
D03 Melanoma in situ
0.765 0.235 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.765 0.235 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.765 0.235 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.765 0.235 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.764 0.236 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.237 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.762 0.238 0.000
M53 Other dorsopathies, not elsewhere classified
0.762 0.238 0.000
C67.1 Dome of bladder
0.762 0.238 0.000
F60-F69 Disorders of adult personality and behaviour
0.761 0.239 0.000
M47 Spondylosis
0.758 0.241 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.756 0.244 0.000
B35-B49 Mycoses
0.756 0.244 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.755 0.245 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.755 0.245 0.000
G80 Infantile cerebral palsy
0.752 0.248 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.749 0.251 0.000
C61 Malignant neoplasm of prostate
0.749 0.251 0.000
M79.0 Rheumatism, unspecified
0.749 0.251 0.000
Y52 Agents primarily affecting the cardiovascular system
0.747 0.253 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.747 0.253 0.000
T86 Failure and rejection of transplanted organs and tissues
0.746 0.254 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.745 0.255 0.000
G62 Other polyneuropathies
0.744 0.256 0.000
M54.6 Pain in thoracic spine
0.744 0.256 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.743 0.257 0.000
H65 Nonsuppurative otitis media
0.742 0.258 0.000
M31 Other necrotising vasculopathies
0.742 0.258 0.000
M81 Osteoporosis without pathological fracture
0.742 0.258 0.000
B15-B19 Viral hepatitis
0.741 0.259 0.000
C67.5 Bladder neck
0.740 0.260 0.000
A00-A09 Intestinal infectious diseases
0.738 0.262 0.000
T91 Sequelae of injuries of neck and trunk
0.738 0.262 0.000
A80-A89 Viral infections of the central nervous system
0.737 0.262 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.737 0.263 0.000
M35 Other systemic involvement of connective tissue
0.737 0.263 0.000
B91 Sequelae of poliomyelitis
0.737 0.263 0.000
H71 Cholesteatoma of middle ear
0.736 0.264 0.000
T43.2 Other and unspecified antidepressants
0.736 0.264 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.736 0.264 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.735 0.264 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.735 0.265 0.000
M46 Other inflammatory spondylopathies
0.733 0.267 0.000
J95-J99 Other diseases of the respiratory system
0.731 0.269 0.000
F30-F39 Mood [affective] disorders
0.730 0.270 0.000
Chapter IX Diseases of the circulatory system
0.729 0.271 0.000
H16 Keratitis
0.727 0.273 0.000
M65-M68 Disorders of synovium and tendon
0.727 0.273 0.000
D48.0 Bone and articular cartilage
0.726 0.274 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.726 0.274 0.000
H66.3 Other chronic suppurative otitis media
0.723 0.277 0.000
C15-C26 Malignant neoplasms of digestive organs
0.722 0.278 0.000
H70.9 Mastoiditis, unspecified
0.719 0.281 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
D60-D64 Aplastic and other anaemias
0.717 0.283 0.000
T51.0 Ethanol
0.714 0.286 0.000
J21 Acute bronchiolitis
0.714 0.286 0.000
J20 Acute bronchitis
0.714 0.286 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.286 0.000
F00 Dementia in Alzheimer's disease
0.713 0.287 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G30.9 Alzheimer's disease, unspecified
0.710 0.290 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.710 0.290 0.000
S70 Superficial injury of hip and thigh
0.710 0.290 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.709 0.291 0.000
H18 Other disorders of cornea
0.709 0.291 0.000
T92 Sequelae of injuries of upper limb
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
H34 Retinal vascular occlusions
0.708 0.292 0.000
M79.8 Other specified soft tissue disorders
0.708 0.292 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.708 0.292 0.000
H21 Other disorders of iris and ciliary body
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.706 0.293 0.000
D09 Carcinoma in situ of other and unspecified sites
0.706 0.294 0.000
D50 Iron deficiency anaemia
0.705 0.295 0.000
F99-F99 Unspecified mental disorder
0.704 0.296 0.000
Y57 Other and unspecified drugs and medicaments
0.703 0.297 0.000
J46 Status asthmaticus
0.703 0.297 0.000
D46 Myelodysplastic syndromes
0.703 0.297 0.000
H55-H59 Other disorders of eye and adnexa
0.702 0.298 0.000
D48.6 Breast
0.701 0.299 0.000
M54.8 Other dorsalgia
0.700 0.300 0.000
M54.0 Panniculitis affecting regions of neck and back
0.700 0.300 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.699 0.301 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.699 0.301 0.000
I30-I52 Other forms of heart disease
0.699 0.301 0.000
H90-H95 Other disorders of ear
0.699 0.301 0.000
H10-H13 Disorders of conjunctiva
0.698 0.301 0.000
M75 Shoulder lesions
0.698 0.302 0.000
H36 Retinal disorders in diseases classified elsewhere
0.698 0.302 0.000
G47 Sleep disorders
0.698 0.302 0.000
J41 Simple and mucopurulent chronic bronchitis
0.698 0.302 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.697 0.303 0.000
M25 Other joint disorders, not elsewhere classified
0.696 0.304 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.695 0.305 0.000
H25-H28 Disorders of lens
0.694 0.306 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.693 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.308 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.308 0.000
I50 Heart failure
0.690 0.310 0.000
T40.4 Other synthetic narcotics
0.690 0.310 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.689 0.310 0.000
H69 Other disorders of Eustachian tube
0.689 0.310 0.000
H68 Eustachian salpingitis and obstruction
0.689 0.310 0.000
H67 Otitis media in diseases classified elsewhere
0.689 0.310 0.000
G83 Other paralytic syndromes
0.689 0.311 0.000
M54.4 Lumbago with sciatica
0.689 0.311 0.000
M79.5 Residual foreign body in soft tissue
0.689 0.311 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.687 0.313 0.000
H40-H42 Glaucoma
0.686 0.314 0.000
G20-G26 Extrapyramidal and movement disorders
0.685 0.315 0.000
D45 Polycythaemia vera
0.685 0.315 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.685 0.315 0.000
C66 Malignant neoplasm of ureter
0.685 0.315 0.000
C65 Malignant neoplasm of renal pelvis
0.685 0.315 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.684 0.316 0.000
W20-W49 Exposure to inanimate mechanical forces
0.683 0.317 0.000
C67.8 Overlapping lesion of bladder
0.682 0.318 0.000
C67.7 Urachus
0.682 0.318 0.000
C67.3 Anterior wall of bladder
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.681 0.319 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.681 0.319 0.000
J04 Acute laryngitis and tracheitis
0.681 0.319 0.000
C15 Malignant neoplasm of oesophagus
0.680 0.320 0.000
T59 Toxic effect of other gases, fumes and vapours
0.680 0.320 0.000
J01 Acute sinusitis
0.679 0.320 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
M31.6 Other giant cell arteritis
0.678 0.322 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.678 0.322 0.000
M54.39 Sciatica (Site unspecified)
0.677 0.323 0.000
F80-F89 Disorders of psychological development
0.677 0.323 0.000
M50 Cervical disk disorders
0.676 0.324 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.676 0.324 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.676 0.324 0.000
M24 Other specific joint derangements
0.675 0.325 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.675 0.325 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.675 0.325 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.675 0.325 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.675 0.325 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.675 0.325 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.675 0.325 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.675 0.325 0.000
Y40 Systemic antibiotics
0.675 0.325 0.000
M54.2 Cervicalgia
0.674 0.326 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.326 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.674 0.326 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.672 0.327 0.000
T93.1 Sequelae of fracture of femur
0.672 0.328 0.000
I42 Cardiomyopathy
0.671 0.329 0.000
C67.6 Ureteric orifice
0.670 0.330 0.000
T90 Sequelae of injuries of head
0.669 0.331 0.000
M48.0 Spinal stenosis
0.669 0.331 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.669 0.331 0.000
H80-H83 Diseases of inner ear
0.669 0.331 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.669 0.331 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.668 0.331 0.000
D07.5 Prostate
0.668 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.668 0.332 0.000
M43 Other deforming dorsopathies
0.668 0.332 0.000
S86 Injury of muscle and tendon at lower leg level
0.667 0.333 0.000
X60-X84 Intentional self-harm
0.667 0.333 0.000
H35.7 Separation of retinal layers
0.667 0.333 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.667 0.333 0.000
I50.9 Heart failure, unspecified
0.667 0.333 0.000
H17 Corneal scars and opacities
0.666 0.334 0.000
G47.3 Sleep apnoea
0.666 0.334 0.000
G60 Hereditary and idiopathic neuropathy
0.666 0.334 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.665 0.334 0.000
H35.4 Peripheral retinal degeneration
0.665 0.335 0.000
M35.0 Sicca syndrome [Sjogren]
0.664 0.336 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.664 0.336 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.664 0.336 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.664 0.336 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.664 0.336 0.000
T63 Toxic effect of contact with venomous animals
0.664 0.336 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.664 0.336 0.000
M71 Other bursopathies
0.663 0.336 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.663 0.337 0.000
M54.56 Low back pain (Lumbar region)
0.663 0.337 0.000
M81.9 Osteoporosis, unspecified
0.663 0.337 0.000
T98 Sequelae of other and unspecified effects of external causes
0.661 0.339 0.000
T95 Sequelae of burns, corrosions and frostbite
0.661 0.339 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.661 0.339 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.661 0.339 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
A30-A49 Other bacterial diseases
0.661 0.339 0.000
D48.7 Other specified sites
0.660 0.340 0.000
T82.1 Mechanical complication of cardiac electronic device
0.659 0.341 0.000
M76 Enthesopathies of lower limb, excluding foot
0.658 0.342 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.658 0.342 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.658 0.342 0.000
F70-F79 Mental retardation
0.658 0.342 0.000
J03 Acute tonsillitis
0.658 0.342 0.000
S80 Superficial injury of lower leg
0.658 0.342 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.657 0.343 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.656 0.343 0.000
T40.8 Lysergide [LSD]
0.656 0.343 0.000
T40.7 Cannabis (derivatives)
0.656 0.343 0.000
T40.6 Other and unspecified narcotics
0.656 0.343 0.000
T40.5 Cocaine
0.656 0.343 0.000
T40.3 Methadone
0.656 0.343 0.000
T40.1 Heroin
0.656 0.343 0.000
T40.0 Opium
0.656 0.343 0.000
S12 Fracture of neck
0.655 0.345 0.000
D48.1 Connective and other soft tissue
0.655 0.345 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.346 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.653 0.346 0.000
M41 Scoliosis
0.653 0.346 0.000
D50.9 Iron deficiency anaemia, unspecified
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.653 0.347 0.000
G81.1 Spastic hemiplegia
0.653 0.347 0.000
G81.0 Flaccid hemiplegia
0.653 0.347 0.000
G82.5 Tetraplegia, unspecified
0.653 0.347 0.000
M75.0 Adhesive capsulitis of shoulder
0.652 0.348 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.651 0.349 0.000
U80 Agent resistant to penicillin and related antibiotics
0.651 0.349 0.000
D55-D59 Haemolytic anaemias
0.650 0.350 0.000
S65 Injury of blood vessels at wrist and hand level
0.649 0.350 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.649 0.351 0.000
J06.0 Acute laryngopharyngitis
0.649 0.351 0.000
M49 Spondylopathies in diseases classified elsewhere
0.649 0.351 0.000
F60 Specific personality disorders
0.649 0.351 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.649 0.351 0.000
Q80-Q89 Other congenital malformations
0.648 0.352 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.648 0.352 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.648 0.352 0.000
M25.5 Pain in joint
0.647 0.353 0.000
C67.4 Posterior wall of bladder
0.647 0.353 0.000
Y86 Sequelae of other accidents
0.647 0.353 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.646 0.354 0.000
M84 Disorders of continuity of bone
0.646 0.354 0.000
M77 Other enthesopathies
0.645 0.355 0.000
D48.5 Skin
0.645 0.355 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.645 0.355 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.645 0.355 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.645 0.355 0.000
H33 Retinal detachments and breaks
0.644 0.356 0.000
J42 Unspecified chronic bronchitis
0.644 0.356 0.000
H66.4 Suppurative otitis media, unspecified
0.644 0.356 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.644 0.356 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.644 0.356 0.000
H66.0 Acute suppurative otitis media
0.644 0.356 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.644 0.356 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.644 0.356 0.000
A08 Viral and other specified intestinal infections
0.643 0.357 0.000
M54.55 Low back pain (Thoracolumbar region)
0.642 0.358 0.000
M54.54 Low back pain-Thoracic
0.642 0.358 0.000
M54.53 Low back pain-Cervicothoracic
0.642 0.358 0.000
M54.52 Low back pain-Cervical
0.642 0.358 0.000
M54.51 Low back pain-Occipit-atl-axl
0.642 0.358 0.000
M54.50 Low back pain (Multiple sites in spine)
0.642 0.358 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.642 0.358 0.000
Y35-Y36 Legal intervention and operations of war
0.642 0.358 0.000
Y10-Y34 Event of undetermined intent
0.642 0.358 0.000
Y00-Y09 Assault
0.642 0.358 0.000
X85-X99 Assault
0.642 0.358 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
X30-X39 Exposure to forces of nature
0.642 0.358 0.000
X20-X29 Contact with venomous animals and plants
0.642 0.358 0.000
X10-X19 Contact with heat and hot substances
0.642 0.358 0.000
X00-X09 Exposure to smoke, fire and flames
0.642 0.358 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.642 0.358 0.000
W75-W84 Other accidental threats to breathing
0.642 0.358 0.000
W65-W74 Accidental drowning and submersion
0.642 0.358 0.000
W50-W64 Exposure to animate mechanical forces
0.642 0.358 0.000
V98-V99 Other and unspecified transport accidents
0.642 0.358 0.000
V95-V97 Air and space transport accidents
0.642 0.358 0.000
V90-V94 Water transport accidents
0.642 0.358 0.000
V80-V89 Other land transport accidents
0.642 0.358 0.000
V70-V79 Bus occupant injured in transport accident
0.642 0.358 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.642 0.358 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.642 0.358 0.000
V40-V49 Car occupant injured in transport accident
0.642 0.358 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.642 0.358 0.000
V01-V09 Pedestrian injured in transport accident
0.642 0.358 0.000
Y88 Sequelae of surgical and medical care as external cause
0.641 0.359 0.000
T65 Toxic effect of other and unspecified substances
0.641 0.359 0.000
T62 Toxic effect of other noxious substances eaten as food
0.641 0.359 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.641 0.359 0.000
T60 Toxic effect of pesticides
0.641 0.359 0.000
T57 Toxic effect of other inorganic substances
0.641 0.359 0.000
T56 Toxic effect of metals
0.641 0.359 0.000
T54 Toxic effect of corrosive substances
0.641 0.359 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.641 0.359 0.000
T52 Toxic effect of organic solvents
0.641 0.359 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.641 0.359 0.000
T58 Toxic effect of carbon monoxide
0.641 0.359 0.000
T55 Toxic effect of soaps and detergents
0.641 0.359 0.000
M47.8 Other spondylosis
0.640 0.360 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.639 0.360 0.000
M79.1 Myalgia
0.639 0.361 0.000
D04.6 Skin of upper limb, including shoulder
0.639 0.361 0.000
H35.8 Other specified retinal disorders
0.639 0.361 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.639 0.361 0.000
S50 Superficial injury of forearm
0.638 0.362 0.000
B33 Other viral diseases, not elsewhere classified
0.637 0.362 0.000
B30 Viral conjunctivitis
0.637 0.362 0.000
B27 Infectious mononucleosis
0.637 0.362 0.000
B26 Mumps
0.637 0.362 0.000
B25 Cytomegaloviral disease
0.637 0.362 0.000
M72 Fibroblastic disorders
0.637 0.362 0.000
H72.8 Other perforations of tympanic membrane
0.637 0.363 0.000
D04.3 Skin of other and unspecified parts of face
0.637 0.363 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.635 0.365 0.000
H31 Other disorders of choroid
0.635 0.365 0.000
H30 Chorioretinal inflammation
0.635 0.365 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.633 0.367 0.000
M86-M90 Other osteopathies
0.633 0.367 0.000
F03 Unspecified dementia
0.632 0.368 0.000
S00-S09 Injuries to the head
0.631 0.369 0.000
D41.4 Bladder
0.631 0.369 0.000
D80-D89 Certain disorders involving the immune mechanism
0.630 0.370 0.000
T93.2 Sequelae of other fractures of lower limb
0.630 0.370 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.630 0.370 0.000
B07 Viral warts
0.629 0.371 0.000
S72 Fracture of femur
0.629 0.371 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.629 0.371 0.000
Y49.5 Other antipsychotics and neuroleptics
0.629 0.371 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.627 0.372 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.627 0.372 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.627 0.372 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.627 0.372 0.000
T42.3 Barbiturates
0.627 0.372 0.000
T42.2 Succinimides and oxazolidinediones
0.627 0.372 0.000
T42.1 Iminostilbenes
0.627 0.372 0.000
T42.0 Hydantoin derivatives
0.627 0.372 0.000
M85 Other disorders of bone density and structure
0.627 0.373 0.000
D04.7 Skin of lower limb, including hip
0.627 0.373 0.000
G64 Other disorders of peripheral nervous system
0.626 0.374 0.000
M79.7 Fibromyalgia
0.625 0.375 0.000
V10-V19 Pedal cyclist injured in transport accident
0.625 0.375 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.625 0.375 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.625 0.375 0.000
H15 Disorders of sclera
0.625 0.375 0.000
S20 Superficial injury of thorax
0.625 0.375 0.000
H72.0 Central perforation of tympanic membrane
0.624 0.376 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.624 0.376 0.000
Q50-Q56 Congenital malformations of genital organs
0.623 0.377 0.000
H16.0 Corneal ulcer
0.623 0.377 0.000
M22 Disorders of patella
0.623 0.377 0.000
S40-S49 Injuries to the shoulder and upper arm
0.623 0.377 0.000
H50 Other strabismus
0.622 0.378 0.000
Y44 Agents primarily affecting blood constituents
0.622 0.378 0.000
S79 Other and unspecified injuries of hip and thigh
0.621 0.379 0.000
H43-H45 Disorders of vitreous body and globe
0.619 0.381 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.619 0.381 0.000
Y85 Sequelae of transport accidents
0.619 0.381 0.000
M79.6 Pain in limb
0.619 0.381 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.618 0.382 0.000
D37.6 Liver, gallbladder and bile ducts
0.618 0.382 0.000
G62.9 Polyneuropathy, unspecified
0.617 0.383 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.617 0.383 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.616 0.384 0.000
M79.9 Soft tissue disorder, unspecified
0.616 0.384 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.616 0.384 0.000
M79.3 Panniculitis, unspecified
0.616 0.384 0.000
M79.2 Neuralgia and neuritis, unspecified
0.616 0.384 0.000
C15.5 Lower third of oesophagus
0.616 0.384 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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