TreeWAS – Variant ID: rs117120368

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.988	0.012	0.000
M80-M85 Disorders of bone density and structure	0.987	0.013	0.000
# Top node	0.986	0.014	0.000
M81 Osteoporosis without pathological fracture	0.985	0.015	0.000
M81.9 Osteoporosis, unspecified	0.984	0.016	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.982	0.018	0.000
Chapter II Neoplasms	0.981	0.019	0.000
D10-D36 Benign neoplasms	0.980	0.020	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.975	0.025	0.000
D17 Benign lipomatous neoplasm	0.973	0.027	0.000
M50-M54 Other dorsopathies	0.952	0.048	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.945	0.055	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.943	0.057	0.000
C64-C68 Malignant neoplasms of urinary tract	0.938	0.062	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.938	0.062	0.000
Chapter XX External causes of morbidity and mortality	0.937	0.063	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.924	0.076	0.000
M54 Dorsalgia	0.923	0.077	0.000
D22 Melanocytic naevi	0.919	0.081	0.000
C67 Malignant neoplasm of bladder	0.917	0.083	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.911	0.089	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.898	0.102	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.888	0.112	0.000
M54.5 Low back pain	0.881	0.119	0.000
S70-S79 Injuries to the hip and thigh	0.873	0.127	0.000
C67.4 Posterior wall of bladder	0.847	0.153	0.000
M54.57 Low back pain (Lumbosacral region)	0.842	0.158	0.000
T66-T78 Other and unspecified effects of external causes	0.836	0.164	0.000
D24 Benign neoplasm of breast	0.836	0.164	0.000
D13.1 Stomach	0.833	0.167	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.833	0.167	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.830	0.170	0.000
D18 Haemangioma and lymphangioma, any site	0.824	0.176	0.000
Chapter V Mental and behavioural disorders	0.824	0.176	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.822	0.178	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.822	0.178	0.000
M50 Cervical disk disorders	0.821	0.179	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.813	0.187	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.811	0.189	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.811	0.189	0.000
Q60-Q64 Congenital malformations of the urinary system	0.810	0.189	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.809	0.190	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.809	0.191	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.804	0.196	0.000
D26 Other benign neoplasms of uterus	0.801	0.199	0.000
M84 Disorders of continuity of bone	0.798	0.202	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.797	0.203	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.796	0.204	0.000
M15-M19 Arthrosis	0.790	0.210	0.000
Chapter XXII Codes for special purposes	0.789	0.211	0.000
M86-M90 Other osteopathies	0.787	0.213	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.786	0.214	0.000
M40-M43 Deforming dorsopathies	0.785	0.215	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.785	0.215	0.000
M85 Other disorders of bone density and structure	0.784	0.216	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.784	0.216	0.000
X60-X84 Intentional self-harm	0.779	0.221	0.000
D31 Benign neoplasm of eye and adnexa	0.771	0.229	0.000
Chapter I Certain infectious and parasitic diseases	0.770	0.230	0.000
M54.1 Radiculopathy	0.765	0.235	0.000
C67.2 Lateral wall of bladder	0.759	0.241	0.000
D32 Benign neoplasm of meninges	0.759	0.241	0.000
E10-E14 Diabetes mellitus	0.758	0.242	0.000
O60-O75 Complications of labour and delivery	0.756	0.244	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.752	0.247	0.000
D46 Myelodysplastic syndromes	0.748	0.252	0.000
M91-M94 Chondropathies	0.748	0.252	0.000
M81.4 Drug-induced osteoporosis	0.745	0.255	0.000
Q80-Q89 Other congenital malformations	0.744	0.256	0.000
Chapter VIII Diseases of the ear and mastoid process	0.742	0.258	0.000
S60-S69 Injuries to the wrist and hand	0.741	0.259	0.000
C60-C63 Malignant neoplasms of male genital organs	0.741	0.259	0.000
S90-S99 Injuries to the ankle and foot	0.738	0.262	0.000
D36 Benign neoplasm of other and unspecified sites	0.737	0.262	0.000
C67.6 Ureteric orifice	0.737	0.263	0.000
M54.56 Low back pain (Lumbar region)	0.736	0.264	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.734	0.265	0.000
S50-S59 Injuries to the elbow and forearm	0.732	0.268	0.000
S20-S29 Injuries to the thorax	0.732	0.268	0.000
T78 Adverse effects, not elsewhere classified	0.731	0.269	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.731	0.269	0.000
S72 Fracture of femur	0.730	0.270	0.000
M65-M68 Disorders of synovium and tendon	0.729	0.271	0.000
C67.9 Bladder, unspecified	0.728	0.272	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.728	0.272	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.727	0.273	0.000
M80 Osteoporosis with pathological fracture	0.726	0.274	0.000
C67.5 Bladder neck	0.726	0.274	0.000
Q50-Q56 Congenital malformations of genital organs	0.725	0.275	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.722	0.278	0.000
W20-W49 Exposure to inanimate mechanical forces	0.722	0.278	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.720	0.280	0.000
T17 Foreign body in respiratory tract	0.720	0.280	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.720	0.280	0.000
T42.4 Benzodiazepines	0.719	0.281	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.718	0.282	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.718	0.282	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.718	0.282	0.000
M50.0 Cervical disk disorder with myelopathy	0.716	0.284	0.000
A30-A49 Other bacterial diseases	0.715	0.285	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.713	0.287	0.000
D18.0 Haemangioma, any site	0.713	0.287	0.000
X20-X29 Contact with venomous animals and plants	0.713	0.287	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.711	0.289	0.000
E11 Non-insulin-dependent diabetes mellitus	0.710	0.290	0.000
Y86 Sequelae of other accidents	0.710	0.290	0.000
T43.2 Other and unspecified antidepressants	0.710	0.290	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.709	0.291	0.000
M60-M63 Disorders of muscles	0.708	0.292	0.000
M00-M03 Infectious arthropathies	0.708	0.292	0.000
T51 Toxic effect of alcohol	0.708	0.292	0.000
M83 Adult osteomalacia	0.708	0.292	0.000
M82 Osteoporosis in diseases classified elsewhere	0.708	0.292	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.707	0.292	0.000
D34 Benign neoplasm of thyroid gland	0.707	0.293	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.707	0.293	0.000
M81.8 Other osteoporosis	0.706	0.293	0.000
M81.6 Localised osteoporosis [Lequesne]	0.706	0.293	0.000
M81.5 Idiopathic osteoporosis	0.706	0.293	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.706	0.293	0.000
M81.2 Osteoporosis of disuse	0.706	0.293	0.000
M81.1 Postoophorectomy osteoporosis	0.706	0.293	0.000
M81.0 Postmenopausal osteoporosis	0.706	0.293	0.000
V40-V49 Car occupant injured in transport accident	0.706	0.294	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.706	0.294	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.706	0.294	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.706	0.294	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.706	0.294	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.706	0.294	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.706	0.294	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.706	0.294	0.000
M81.98 Osteoporosis, unspecified (Other)	0.705	0.295	0.000
M54.3 Sciatica	0.705	0.295	0.000
T33-T35 Frostbite	0.704	0.296	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.704	0.296	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.704	0.296	0.000
T00-T07 Injuries involving multiple body regions	0.704	0.296	0.000
S10-S19 Injuries to the neck	0.704	0.296	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.703	0.297	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.703	0.297	0.000
M05-M14 Inflammatory polyarthropathies	0.703	0.297	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.703	0.297	0.000
D30 Benign neoplasm of urinary organs	0.702	0.297	0.000
D29 Benign neoplasm of male genital organs	0.702	0.297	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.702	0.297	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.702	0.297	0.000
D19 Benign neoplasm of mesothelial tissue	0.702	0.297	0.000
D16 Benign neoplasm of bone and articular cartilage	0.702	0.297	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.702	0.297	0.000
M16 Coxarthrosis [arthrosis of hip]	0.701	0.299	0.000
M54.9 Dorsalgia, unspecified	0.700	0.300	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.698	0.302	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.698	0.302	0.000
S70 Superficial injury of hip and thigh	0.698	0.302	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.697	0.302	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.697	0.303	0.000
D27 Benign neoplasm of ovary	0.695	0.305	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.695	0.305	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.695	0.305	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.695	0.305	0.000
W00-W19 Falls	0.694	0.306	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.693	0.307	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.691	0.309	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.689	0.310	0.000
S40-S49 Injuries to the shoulder and upper arm	0.689	0.311	0.000
O70 Perineal laceration during delivery	0.689	0.311	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.688	0.312	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.687	0.313	0.000
S79 Other and unspecified injuries of hip and thigh	0.683	0.317	0.000
M53 Other dorsopathies, not elsewhere classified	0.682	0.318	0.000
F80-F89 Disorders of psychological development	0.680	0.320	0.000
S80-S89 Injuries to the knee and lower leg	0.680	0.320	0.000
S00-S09 Injuries to the head	0.679	0.321	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.677	0.323	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.677	0.323	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.676	0.323	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.676	0.323	0.000
Q35-Q37 Cleft lip and cleft palate	0.676	0.323	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.676	0.323	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.676	0.323	0.000
Q00-Q07 Congenital malformations of the nervous system	0.676	0.323	0.000
T79-T79 Certain early complications of trauma	0.675	0.324	0.000
D10 Benign neoplasm of mouth and pharynx	0.673	0.327	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.673	0.327	0.000
C66 Malignant neoplasm of ureter	0.673	0.327	0.000
C65 Malignant neoplasm of renal pelvis	0.673	0.327	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.671	0.328	0.000
Y35-Y36 Legal intervention and operations of war	0.671	0.328	0.000
Y10-Y34 Event of undetermined intent	0.671	0.328	0.000
Y00-Y09 Assault	0.671	0.328	0.000
X85-X99 Assault	0.671	0.328	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.671	0.328	0.000
X50-X57 Overexertion, travel and privation	0.671	0.328	0.000
X30-X39 Exposure to forces of nature	0.671	0.328	0.000
X10-X19 Contact with heat and hot substances	0.671	0.328	0.000
X00-X09 Exposure to smoke, fire and flames	0.671	0.328	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.671	0.328	0.000
W75-W84 Other accidental threats to breathing	0.671	0.328	0.000
W65-W74 Accidental drowning and submersion	0.671	0.328	0.000
W50-W64 Exposure to animate mechanical forces	0.671	0.328	0.000
V98-V99 Other and unspecified transport accidents	0.671	0.328	0.000
V95-V97 Air and space transport accidents	0.671	0.328	0.000
V90-V94 Water transport accidents	0.671	0.328	0.000
V80-V89 Other land transport accidents	0.671	0.328	0.000
V70-V79 Bus occupant injured in transport accident	0.671	0.328	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.671	0.328	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.671	0.328	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.671	0.328	0.000
V01-V09 Pedestrian injured in transport accident	0.671	0.328	0.000
M54.12 Radiculopathy (Cervical region)	0.667	0.332	0.000
O80-O84 Delivery	0.667	0.333	0.000
C01 Malignant neoplasm of base of tongue	0.664	0.336	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.664	0.336	0.000
M50.1 Cervical disk disorder with radiculopathy	0.663	0.337	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.663	0.337	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.663	0.337	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.663	0.337	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.663	0.337	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.663	0.337	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.663	0.337	0.000
T36 Poisoning by systemic antibiotics	0.663	0.337	0.000
M54.8 Other dorsalgia	0.661	0.338	0.000
M54.6 Pain in thoracic spine	0.661	0.338	0.000
M54.0 Panniculitis affecting regions of neck and back	0.661	0.338	0.000
A41 Other septicaemia	0.659	0.341	0.000
D22.9 Melanocytic naevi, unspecified	0.659	0.341	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.659	0.341	0.000
C67.8 Overlapping lesion of bladder	0.657	0.343	0.000
C67.7 Urachus	0.657	0.343	0.000
C67.3 Anterior wall of bladder	0.657	0.343	0.000
C67.1 Dome of bladder	0.657	0.343	0.000
C67.0 Trigone of bladder	0.657	0.343	0.000
O70.1 Second degree perineal laceration during delivery	0.656	0.344	0.000
Q21 Congenital malformations of cardiac septa	0.654	0.346	0.000
Y85 Sequelae of transport accidents	0.653	0.347	0.000
Q23 Congenital malformations of aortic and mitral valves	0.652	0.348	0.000
S62 Fracture at wrist and hand level	0.652	0.348	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.651	0.348	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.649	0.350	0.000
M54.4 Lumbago with sciatica	0.648	0.352	0.000
H60-H62 Diseases of external ear	0.648	0.352	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.646	0.354	0.000
T92 Sequelae of injuries of upper limb	0.646	0.354	0.000
M20-M25 Other joint disorders	0.646	0.354	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.645	0.355	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.645	0.355	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.644	0.356	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.644	0.356	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.644	0.356	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.644	0.356	0.000
D26.0 Cervix uteri	0.644	0.356	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.641	0.359	0.000
T81 Complications of procedures, not elsewhere classified	0.639	0.361	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.639	0.361	0.000
D13.9 Ill-defined sites within the digestive system	0.637	0.363	0.000
D13.7 Endocrine pancreas	0.637	0.363	0.000
D13.6 Pancreas	0.637	0.363	0.000
D13.5 Extrahepatic bile ducts	0.637	0.363	0.000
D13.4 Liver	0.637	0.363	0.000
D13.3 Other and unspecified parts of small intestine	0.637	0.363	0.000
D13.0 Oesophagus	0.637	0.363	0.000
E13 Other specified diabetes mellitus	0.636	0.364	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.634	0.366	0.000
M86 Osteomyelitis	0.633	0.367	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.633	0.367	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.633	0.367	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.633	0.367	0.000
V20-V29 Motorcycle rider injured in transport accident	0.633	0.367	0.000
M54.55 Low back pain (Thoracolumbar region)	0.632	0.368	0.000
M54.54 Low back pain-Thoracic	0.632	0.368	0.000
M54.53 Low back pain-Cervicothoracic	0.632	0.368	0.000
M54.52 Low back pain-Cervical	0.632	0.368	0.000
M54.51 Low back pain-Occipit-atl-axl	0.632	0.368	0.000
M54.50 Low back pain (Multiple sites in spine)	0.632	0.368	0.000
M54.2 Cervicalgia	0.630	0.369	0.000
M16.1 Other primary coxarthrosis	0.629	0.371	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.627	0.373	0.000
S78 Traumatic amputation of hip and thigh	0.626	0.374	0.000
S77 Crushing injury of hip and thigh	0.626	0.374	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.626	0.374	0.000
S75 Injury of blood vessels at hip and thigh level	0.626	0.374	0.000
S74 Injury of nerves at hip and thigh level	0.626	0.374	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.626	0.374	0.000
S71 Open wound of hip and thigh	0.626	0.374	0.000
A41.9 Septicaemia, unspecified	0.626	0.374	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.626	0.374	0.000
F30-F39 Mood [affective] disorders	0.625	0.375	0.000
E11.6 With other specified complications	0.625	0.375	0.000
M85.0 Fibrous dysplasia (monostotic)	0.624	0.376	0.000
E20-E35 Disorders of other endocrine glands	0.623	0.377	0.000
D31.3 Choroid	0.622	0.378	0.000
Q61 Cystic kidney disease	0.618	0.382	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.617	0.383	0.000
M41 Scoliosis	0.617	0.383	0.000
D26.1 Corpus uteri	0.617	0.383	0.000
O72 Postpartum haemorrhage	0.617	0.383	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.617	0.383	0.000
D11 Benign neoplasm of major salivary glands	0.615	0.385	0.000
S72.1 Pertrochanteric fracture	0.614	0.386	0.000
T51.0 Ethanol	0.614	0.386	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.613	0.387	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.612	0.388	0.000
M84.0 Malunion of fracture	0.612	0.388	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.611	0.389	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.610	0.389	0.000
O85-O92 Complications predominantly related to the puerperium	0.610	0.390	0.000
D32.0 Cerebral meninges	0.608	0.392	0.000
F60-F69 Disorders of adult personality and behaviour	0.608	0.392	0.000
V10-V19 Pedal cyclist injured in transport accident	0.608	0.392	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.607	0.393	0.000
T90 Sequelae of injuries of head	0.605	0.395	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.605	0.395	0.000
M50.3 Other cervical disk degeneration	0.605	0.395	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.604	0.396	0.000
M06 Other rheumatoid arthritis	0.603	0.396	0.000
D00-D09 In situ neoplasms	0.601	0.398	0.001
D22.0 Melanocytic naevi of lip	0.602	0.398	0.000
S99 Other and unspecified injuries of ankle and foot	0.602	0.398	0.000
T78.4 Allergy, unspecified	0.601	0.399	0.000
Q82 Other congenital malformations of skin	0.600	0.400	0.000
T75 Effects of other external causes	0.599	0.400	0.000
T74 Maltreatment syndromes	0.599	0.400	0.000
T73 Effects of other deprivation	0.599	0.400	0.000
T70 Effects of air pressure and water pressure	0.599	0.400	0.000
T69 Other effects of reduced temperature	0.599	0.400	0.000
T67 Effects of heat and light	0.599	0.400	0.000
T71 Asphyxiation	0.599	0.400	0.000
T68 Hypothermia	0.599	0.400	0.000
T66 Unspecified effects of radiation	0.599	0.400	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.598	0.402	0.000
T17.2 Foreign body in pharynx	0.595	0.405	0.000
M43 Other deforming dorsopathies	0.594	0.406	0.000
S72.4 Fracture of lower end of femur	0.594	0.406	0.000
Chapter VI Diseases of the nervous system	0.594	0.406	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.594	0.406	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.593	0.407	0.000
D18.1 Lymphangioma, any site	0.591	0.409	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.591	0.409	0.000
F70-F79 Mental retardation	0.591	0.409	0.000
E10 Insulin-dependent diabetes mellitus	0.591	0.409	0.000
D47.2 Monoclonal gammopathy	0.590	0.409	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.590	0.410	0.000
T65 Toxic effect of other and unspecified substances	0.590	0.410	0.000
T63 Toxic effect of contact with venomous animals	0.590	0.410	0.000
T62 Toxic effect of other noxious substances eaten as food	0.590	0.410	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.590	0.410	0.000
T60 Toxic effect of pesticides	0.590	0.410	0.000
T59 Toxic effect of other gases, fumes and vapours	0.590	0.410	0.000
T57 Toxic effect of other inorganic substances	0.590	0.410	0.000
T56 Toxic effect of metals	0.590	0.410	0.000
T54 Toxic effect of corrosive substances	0.590	0.410	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.590	0.410	0.000
T52 Toxic effect of organic solvents	0.590	0.410	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.590	0.410	0.000
T58 Toxic effect of carbon monoxide	0.590	0.410	0.000
T55 Toxic effect of soaps and detergents	0.590	0.410	0.000
Y89 Sequelae of other external causes	0.590	0.410	0.000
Y88 Sequelae of surgical and medical care as external cause	0.590	0.410	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.590	0.410	0.000
S51 Open wound of forearm	0.589	0.411	0.000
M50.9 Cervical disk disorder, unspecified	0.588	0.412	0.000
M50.8 Other cervical disk disorders	0.588	0.412	0.000
D47.1 Chronic myeloproliferative disease	0.587	0.412	0.000
F99-F99 Unspecified mental disorder	0.587	0.413	0.000
D13.2 Duodenum	0.586	0.414	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.586	0.414	0.000
M90 Osteopathies in diseases classified elsewhere	0.585	0.415	0.000
T78.2 Anaphylactic shock, unspecified	0.585	0.415	0.000
S80 Superficial injury of lower leg	0.584	0.416	0.000
Q60.2 Renal agenesis, unspecified	0.583	0.417	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.583	0.417	0.000
C13 Malignant neoplasm of hypopharynx	0.583	0.417	0.000
C11 Malignant neoplasm of nasopharynx	0.583	0.417	0.000
C10 Malignant neoplasm of oropharynx	0.583	0.417	0.000
C09 Malignant neoplasm of tonsil	0.583	0.417	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.583	0.417	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.583	0.417	0.000
C05 Malignant neoplasm of palate	0.583	0.417	0.000
C04 Malignant neoplasm of floor of mouth	0.583	0.417	0.000
C03 Malignant neoplasm of gum	0.583	0.417	0.000
C00 Malignant neoplasm of lip	0.583	0.417	0.000
C12 Malignant neoplasm of pyriform sinus	0.583	0.417	0.000
C07 Malignant neoplasm of parotid gland	0.583	0.417	0.000
M85.8 Other specified disorders of bone density and structure	0.582	0.418	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.582	0.418	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.582	0.418	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.582	0.418	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.582	0.418	0.000
T42.3 Barbiturates	0.582	0.418	0.000
T42.2 Succinimides and oxazolidinediones	0.582	0.418	0.000
T42.1 Iminostilbenes	0.582	0.418	0.000
T42.0 Hydantoin derivatives	0.582	0.418	0.000
T19 Foreign body in genito-urinary tract	0.581	0.418	0.000
T15 Foreign body on external eye	0.581	0.418	0.000
T16 Foreign body in ear	0.581	0.418	0.000
Q64 Other congenital malformations of urinary system	0.581	0.419	0.000
Q63 Other congenital malformations of kidney	0.581	0.419	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.581	0.419	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.581	0.419	0.000
W22 Striking against or struck by other objects	0.581	0.419	0.000
T43.9 Psychotropic drug, unspecified	0.580	0.419	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.580	0.419	0.000
T43.6 Psychostimulants with abuse potential	0.580	0.419	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.580	0.419	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.580	0.419	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.580	0.419	0.000
D45 Polycythaemia vera	0.580	0.420	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.578	0.422	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.577	0.423	0.000
F81 Specific developmental disorders of scholastic skills	0.577	0.423	0.000
E11.2 With renal complications	0.577	0.423	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.576	0.423	0.000
Q28 Other congenital malformations of circulatory system	0.576	0.423	0.000
Q27 Other congenital malformations of peripheral vascular system	0.576	0.423	0.000
Q26 Congenital malformations of great veins	0.576	0.423	0.000
Q25 Congenital malformations of great arteries	0.576	0.423	0.000
Q24 Other congenital malformations of heart	0.576	0.423	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.576	0.423	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.576	0.423	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.576	0.424	0.000
D26.9 Uterus, unspecified	0.574	0.425	0.000
D26.7 Other parts of uterus	0.574	0.425	0.000
A49 Bacterial infection of unspecified site	0.574	0.425	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.574	0.426	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.573	0.427	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.572	0.427	0.000
M84.9 Disorder of continuity of bone, unspecified	0.572	0.428	0.000
M84.8 Other disorders of continuity of bone	0.572	0.428	0.000
M84.4 Pathological fracture, not elsewhere classified	0.572	0.428	0.000
M84.3 Stress fracture, not elsewhere classified	0.572	0.428	0.000
M84.2 Delayed union of fracture	0.572	0.428	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.572	0.428	0.000
Q66 Congenital deformities of feet	0.571	0.429	0.000
E40-E46 Malnutrition	0.571	0.429	0.000
F20 Schizophrenia	0.571	0.429	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.571	0.429	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.571	0.429	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.571	0.429	0.000
D47.4 Osteomyelofibrosis	0.571	0.429	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.571	0.429	0.000
M88 Paget's disease of bone [osteitis deformans]	0.570	0.429	0.000
E11.3 With ophthalmic complications	0.569	0.431	0.000
C61 Malignant neoplasm of prostate	0.569	0.431	0.000
E11.4 With neurological complications	0.569	0.431	0.000
D35.2 Pituitary gland	0.568	0.432	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.568	0.432	0.000
M94 Other disorders of cartilage	0.568	0.432	0.000
T86 Failure and rejection of transplanted organs and tissues	0.567	0.433	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.567	0.433	0.000
D80-D89 Certain disorders involving the immune mechanism	0.567	0.433	0.000
S09 Other and unspecified injuries of head	0.567	0.433	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.566	0.434	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.566	0.434	0.000
M15 Polyarthrosis	0.566	0.434	0.000
F29 Unspecified nonorganic psychosis	0.566	0.434	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.564	0.436	0.000
Y84.2 Radiological procedure and radiotherapy	0.564	0.436	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.564	0.436	0.000
M42 Spinal osteochondrosis	0.563	0.437	0.000
M40 Kyphosis and lordosis	0.563	0.437	0.000
Y40 Systemic antibiotics	0.563	0.437	0.000
T78.3 Angioneurotic oedema	0.563	0.437	0.000
S31 Open wound of abdomen, lower back and pelvis	0.563	0.437	0.000
A80-A89 Viral infections of the central nervous system	0.563	0.437	0.000
M87 Osteonecrosis	0.562	0.438	0.000
M85.9 Disorder of bone density and structure, unspecified	0.562	0.438	0.000
M85.6 Other cyst of bone	0.562	0.438	0.000
M85.5 Aneurysmal bone cyst	0.562	0.438	0.000
M85.4 Solitary bone cyst	0.562	0.438	0.000
M85.3 Osteitis condensans	0.562	0.438	0.000
M85.2 Hyperostosis of skull	0.562	0.438	0.000
M85.1 Skeletal fluorosis	0.562	0.438	0.000
T98 Sequelae of other and unspecified effects of external causes	0.562	0.438	0.000
T95 Sequelae of burns, corrosions and frostbite	0.562	0.438	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.562	0.438	0.000
T91 Sequelae of injuries of neck and trunk	0.562	0.438	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.562	0.438	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.562	0.438	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.561	0.439	0.000
M21 Other acquired deformities of limbs	0.561	0.439	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.561	0.439	0.000
S62.3 Fracture of other metacarpal bone	0.560	0.440	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.559	0.441	0.000
X84 Intentional self-harm by unspecified means	0.559	0.441	0.000
X83 Intentional self-harm by other specified means	0.559	0.441	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.559	0.441	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.559	0.441	0.000
X80 Intentional self-harm by jumping from a high place	0.559	0.441	0.000
X79 Intentional self-harm by blunt object	0.559	0.441	0.000
X78 Intentional self-harm by sharp object	0.559	0.441	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.559	0.441	0.000
X76 Intentional self-harm by smoke, fire and flames	0.559	0.441	0.000
X75 Intentional self-harm by explosive material	0.559	0.441	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.559	0.441	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.559	0.441	0.000
X72 Intentional self-harm by handgun discharge	0.559	0.441	0.000
X71 Intentional self-harm by drowning and submersion	0.559	0.441	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.559	0.441	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.559	0.441	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.559	0.441	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations