TreeWAS – Variant ID: rs11713169

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D69.6 Thrombocytopenia, unspecified	0.177	0.823	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.170	0.830	0.000
D69 Purpura and other haemorrhagic conditions	0.168	0.832	0.000
D69.4 Other primary thrombocytopenia	0.134	0.866	0.000
D69.0 Allergic purpura	0.128	0.872	0.000
D69.8 Other specified haemorrhagic conditions	0.121	0.879	0.000
D69.2 Other nonthrombocytopenic purpura	0.121	0.879	0.000
D69.1 Qualitative platelet defects	0.121	0.879	0.000
D69.9 Haemorrhagic condition, unspecified	0.112	0.888	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.915	0.085
D69.5 Secondary thrombocytopenia	0.079	0.921	0.001
Z63 Other problems related to primary support group, including family circumstances	0.045	0.955	0.000
Z63.4 Disappearance and death of family member	0.043	0.957	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.043	0.957	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.041	0.958	0.002
Z59 Problems related to housing and economic circumstances	0.041	0.959	0.000
Z63.8 Other specified problems related to primary support group	0.040	0.960	0.000
Z63.0 Problems in relationship with spouse or partner	0.039	0.961	0.000
Z61 Problems related to negative life events in childhood	0.038	0.962	0.000
Z56 Problems related to employment and unemployment	0.038	0.962	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.038	0.962	0.000
Z57 Occupational exposure to risk-factors	0.037	0.963	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.036	0.964	0.000
Z63.7 Other stressful life events affecting family and household	0.035	0.965	0.000
Z56.6 Other physical and mental strain related to work	0.035	0.965	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.035	0.965	0.000
Z63.9 Problem related to primary support group, unspecified	0.033	0.967	0.000
Z63.3 Absence of family member	0.033	0.967	0.000
Z63.2 Inadequate family support	0.033	0.967	0.000
Z63.1 Problems in relationship with parents and in-laws	0.033	0.967	0.000
Z63.6 Dependent relative needing care at home	0.033	0.967	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.032	0.968	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.032	0.968	0.000
Z59.1 Inadequate housing	0.032	0.968	0.000
Z65 Problems related to other psychosocial circumstances	0.031	0.969	0.000
Z62 Other problems related to upbringing	0.031	0.969	0.000
Z55 Problems related to education and literacy	0.031	0.969	0.000
D67 Hereditary factor IX deficiency	0.029	0.969	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.031	0.969	0.000
Z64 Problems related to certain psychosocial circumstances	0.030	0.970	0.000
Z58 Problems related to physical environment	0.030	0.970	0.000
Z56.3 Stressful work schedule	0.030	0.970	0.000
Z59.7 Insufficient social insurance and welfare support	0.029	0.970	0.000
Z59.6 Low income	0.029	0.970	0.000
Z59.5 Extreme poverty	0.029	0.970	0.000
Z59.4 Lack of adequate food	0.029	0.970	0.000
Z59.3 Problems related to living in residential institution	0.029	0.970	0.000
Z59.0 Homelessness	0.029	0.970	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.028	0.971	0.002
Z57.8 Occupational exposure to other risk-factors	0.029	0.971	0.000
Z63.5 Disruption of family by separation and divorce	0.028	0.972	0.000
Z61.9 Negative life events in childhood, unspecified	0.028	0.972	0.000
Z61.8 Other negative life events in childhood	0.028	0.972	0.000
Z61.7 Personal frightening experience in childhood	0.028	0.972	0.000
Z61.6 Problems related to alleged physical abuse of child	0.028	0.972	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.028	0.972	0.000
Z61.2 Altered pattern of family relationships in childhood	0.028	0.972	0.000
Z61.1 Removal from home in childhood	0.028	0.972	0.000
Z61.0 Loss of love relationship in childhood	0.028	0.972	0.000
Z56.7 Other and unspecified problems related to employment	0.027	0.972	0.000
Z56.5 Uncongenial work	0.027	0.972	0.000
Z56.4 Discord with boss and workmates	0.027	0.972	0.000
Z56.2 Threat of job loss	0.027	0.972	0.000
Z56.1 Change of job	0.027	0.972	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.027	0.973	0.000
Z57.7 Occupational exposure to vibration	0.027	0.973	0.000
Z57.6 Occupational exposure to extreme temperature	0.027	0.973	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.027	0.973	0.000
Z57.1 Occupational exposure to radiation	0.027	0.973	0.000
Z57.0 Occupational exposure to noise	0.027	0.973	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.026	0.974	0.000
Z56.0 Unemployment, unspecified	0.025	0.975	0.000
D80-D89 Certain disorders involving the immune mechanism	0.025	0.975	0.000
Z58.5 Exposure to other pollution	0.023	0.977	0.000
D66 Hereditary factor VIII deficiency	0.021	0.977	0.002
D80 Immunodeficiency with predominantly antibody defects	0.023	0.977	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.022	0.977	0.000
Z55.8 Other problems relating to education and literacy	0.022	0.977	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.022	0.977	0.000
Z55.3 Underachievement in school	0.022	0.977	0.000
Z55.2 Failed examinations	0.022	0.977	0.000
Z55.1 Schooling unavailable and unattainable	0.022	0.977	0.000
Z55.0 Illiteracy and low-level literacy	0.022	0.977	0.000
Z62.9 Problem related to upbringing, unspecified	0.022	0.977	0.000
Z62.8 Other specified problems related to upbringing	0.022	0.977	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.022	0.977	0.000
Z62.5 Other problems related to neglect in upbringing	0.022	0.977	0.000
Z62.4 Emotional neglect of child	0.022	0.977	0.000
Z62.3 Hostility towards and scapegoating of child	0.022	0.977	0.000
Z62.2 Institutional upbringing	0.022	0.977	0.000
Z62.1 Parental overprotection	0.022	0.977	0.000
Z62.0 Inadequate parental supervision and control	0.022	0.977	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.022	0.977	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.022	0.977	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.022	0.977	0.000
Z65.4 Victim of crime and terrorism	0.022	0.977	0.000
Z65.3 Problems related to other legal circumstances	0.022	0.977	0.000
Z65.2 Problems related to release from prison	0.022	0.977	0.000
Z65.1 Imprisonment and other incarceration	0.022	0.977	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.022	0.977	0.000
D55-D59 Haemolytic anaemias	0.022	0.978	0.000
D86 Sarcoidosis	0.022	0.978	0.000
Z64.4 Discord with counsellors	0.022	0.978	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.022	0.978	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.022	0.978	0.000
Z64.1 Problems related to multiparity	0.022	0.978	0.000
Z58.9 Problem related to physical environment, unspecified	0.022	0.978	0.000
Z58.7 Exposure to tobacco smoke	0.022	0.978	0.000
Z58.6 Inadequate drinking-water supply	0.022	0.978	0.000
Z58.4 Exposure to radiation	0.022	0.978	0.000
Z58.3 Exposure to soil pollution	0.022	0.978	0.000
Z58.2 Exposure to water pollution	0.022	0.978	0.000
Z58.0 Exposure to noise	0.022	0.978	0.000
Z64.0 Problems related to unwanted pregnancy	0.021	0.979	0.000
Z58.8 Other problems related to physical environment	0.021	0.979	0.000
F32.1 Moderate depressive episode	0.021	0.979	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.980	0.020
Z58.1 Exposure to air pollution	0.020	0.980	0.000
D50-D53 Nutritional anaemias	0.019	0.981	0.000
D59 Acquired haemolytic anaemia	0.019	0.981	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.019	0.981	0.000
D86.0 Sarcoidosis of lung	0.019	0.981	0.000
Z60 Problems related to social environment	0.019	0.981	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.019	0.981	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.019	0.981	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.018	0.981	0.000
D51 Vitamin B12 deficiency anaemia	0.018	0.982	0.000
D86.9 Sarcoidosis, unspecified	0.018	0.982	0.000
F32 Depressive episode	0.018	0.982	0.000
D83 Common variable immunodeficiency	0.018	0.982	0.000
D82 Immunodeficiency associated with other major defects	0.018	0.982	0.000
D81 Combined immunodeficiencies	0.018	0.982	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.018	0.982	0.000
D60-D64 Aplastic and other anaemias	0.018	0.982	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.018	0.982	0.000
F30-F39 Mood [affective] disorders	0.018	0.982	0.000
F31 Bipolar affective disorder	0.018	0.982	0.000
D58 Other hereditary haemolytic anaemias	0.017	0.983	0.000
Z57.3 Occupational exposure to other air contaminants	0.017	0.983	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.016	0.983	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.016	0.983	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.016	0.983	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.016	0.983	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.016	0.983	0.000
F33 Recurrent depressive disorder	0.016	0.983	0.000
D84 Other immunodeficiencies	0.016	0.984	0.000
D86.1 Sarcoidosis of lymph nodes	0.016	0.984	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.016	0.984	0.000
D59.1 Other autoimmune haemolytic anaemias	0.016	0.984	0.000
D57 Sickle-cell disorders	0.016	0.984	0.000
D55 Anaemia due to enzyme disorders	0.016	0.984	0.000
D86.3 Sarcoidosis of skin	0.016	0.984	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.016	0.984	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.016	0.984	0.000
D53 Other nutritional anaemias	0.016	0.984	0.000
D62 Acute posthaemorrhagic anaemia	0.015	0.985	0.000
D86.8 Sarcoidosis of other and combined sites	0.015	0.985	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.015	0.985	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.015	0.985	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.015	0.985	0.000
D56 Thalassaemia	0.015	0.985	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.014	0.985	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.014	0.986	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.014	0.986	0.000
Z57.2 Occupational exposure to dust	0.014	0.986	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.014	0.986	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.014	0.986	0.000
F33.9 Recurrent depressive disorder, unspecified	0.014	0.986	0.000
Z47 Other orthopaedic follow-up care	0.000	0.986	0.014
F34 Persistent mood [affective] disorders	0.014	0.986	0.000
F31.8 Other bipolar affective disorders	0.014	0.986	0.000
Z60.9 Problem related to social environment, unspecified	0.014	0.986	0.000
D59.8 Other acquired haemolytic anaemias	0.014	0.986	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.014	0.986	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.014	0.986	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.014	0.986	0.000
D59.3 Haemolytic-uraemic syndrome	0.014	0.986	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.014	0.986	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.014	0.986	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.014	0.986	0.000
Z60.8 Other problems related to social environment	0.014	0.986	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.014	0.986	0.000
Z60.4 Social exclusion and rejection	0.014	0.986	0.000
Z60.3 Acculturation difficulty	0.014	0.986	0.000
Z60.1 Atypical parenting situation	0.014	0.986	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.014	0.986	0.000
F30 Manic episode	0.014	0.986	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.014	0.986	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.013	0.986	0.000
D89.3 Immune reconstitution syndrome	0.013	0.986	0.000
D89.1 Cryoglobulinaemia	0.013	0.986	0.000
F31.7 Bipolar affective disorder, currently in remission	0.013	0.986	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.013	0.987	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.013	0.987	0.000
D51.2 Transcobalamin II deficiency	0.013	0.987	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.013	0.987	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.013	0.987	0.000
F32.0 Mild depressive episode	0.013	0.987	0.000
D81.9 Combined immunodeficiency, unspecified	0.013	0.987	0.000
D81.8 Other combined immunodeficiencies	0.013	0.987	0.000
D81.7 Major histocompatibility complex class II deficiency	0.013	0.987	0.000
D81.6 Major histocompatibility complex class I deficiency	0.013	0.987	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.013	0.987	0.000
D81.4 Nezelof's syndrome	0.013	0.987	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.013	0.987	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.013	0.987	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.013	0.987	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.013	0.987	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.013	0.987	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.013	0.987	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.013	0.987	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.013	0.987	0.000
D82.2 Immunodeficiency with short-limbed stature	0.013	0.987	0.000
D82.1 Di George's syndrome	0.013	0.987	0.000
D82.0 Wiskott-Aldrich syndrome	0.013	0.987	0.000
D83.9 Common variable immunodeficiency, unspecified	0.013	0.987	0.000
D83.8 Other common variable immunodeficiencies	0.013	0.987	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.013	0.987	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.013	0.987	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.013	0.987	0.000
D61 Other aplastic anaemias	0.013	0.987	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.013	0.987	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.013	0.987	0.000
D53.9 Nutritional anaemia, unspecified	0.013	0.987	0.000
F38 Other mood [affective] disorders	0.013	0.987	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.013	0.987	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.987	0.013
D58.8 Other specified hereditary haemolytic anaemias	0.012	0.987	0.000
D58.2 Other haemoglobinopathies	0.012	0.987	0.000
D58.1 Hereditary elliptocytosis	0.012	0.987	0.000
D58.0 Hereditary spherocytosis	0.012	0.987	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.012	0.988	0.000
F32.8 Other depressive episodes	0.012	0.988	0.000
F33.8 Other recurrent depressive disorders	0.012	0.988	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.012	0.988	0.000
D84.8 Other specified immunodeficiencies	0.012	0.988	0.000
D84.1 Defects in the complement system	0.012	0.988	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.012	0.988	0.000
D63.0 Anaemia in neoplastic disease	0.012	0.988	0.000
D52 Folate deficiency anaemia	0.012	0.988	0.000
Q80-Q89 Other congenital malformations	0.012	0.988	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.012	0.988	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.012	0.988	0.000
D55.8 Other anaemias due to enzyme disorders	0.012	0.988	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.012	0.988	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.012	0.988	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.012	0.988	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.012	0.988	0.000
D57.8 Other sickle-cell disorders	0.012	0.988	0.000
D57.3 Sickle-cell trait	0.012	0.988	0.000
D57.2 Double heterozygous sickling disorders	0.012	0.988	0.000
D57.1 Sickle-cell anaemia without crisis	0.012	0.988	0.000
D57.0 Sickle-cell anaemia with crisis	0.012	0.988	0.000
F30.9 Manic episode, unspecified	0.012	0.988	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.988	0.012
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.012	0.988	0.000
F34.1 Dysthymia	0.012	0.988	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.012	0.988	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.000	0.988	0.012
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.012	0.988	0.000
D53.8 Other specified nutritional anaemias	0.011	0.988	0.000
D53.2 Scorbutic anaemia	0.011	0.988	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.011	0.988	0.000
D53.0 Protein deficiency anaemia	0.011	0.988	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.011	0.989	0.000
D56.9 Thalassaemia, unspecified	0.011	0.989	0.000
D56.8 Other thalassaemias	0.011	0.989	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.011	0.989	0.000
D56.2 Delta-beta thalassaemia	0.011	0.989	0.000
D56.0 Alpha thalassaemia	0.011	0.989	0.000
F39 Unspecified mood [affective] disorder	0.011	0.989	0.000
F31.9 Bipolar affective disorder, unspecified	0.011	0.989	0.000
D56.1 Beta thalassaemia	0.011	0.989	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.011	0.989	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.989	0.011
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.011	0.989	0.000
Q00-Q07 Congenital malformations of the nervous system	0.011	0.989	0.000
Q66 Congenital deformities of feet	0.011	0.989	0.000
Q89 Other congenital malformations, not elsewhere classified	0.011	0.989	0.000
F30.0 Hypomania	0.010	0.989	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.010	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.010	0.990	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.010	0.990	0.000
F34.8 Other persistent mood [affective] disorders	0.010	0.990	0.000
F34.0 Cyclothymia	0.010	0.990	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.010	0.990	0.000
F30.8 Other manic episodes	0.010	0.990	0.000
F30.1 Mania without psychotic symptoms	0.010	0.990	0.000
D56.3 Thalassaemia trait	0.010	0.990	0.000
Q87.4 Marfan's syndrome	0.010	0.990	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.010	0.990	0.000
Q24 Other congenital malformations of heart	0.010	0.990	0.000
Q89.2 Congenital malformations of other endocrine glands	0.010	0.990	0.000
D68.8 Other specified coagulation defects	0.000	0.990	0.009
D61.9 Aplastic anaemia, unspecified	0.010	0.990	0.000
D61.8 Other specified aplastic anaemias	0.010	0.990	0.000
D61.3 Idiopathic aplastic anaemia	0.010	0.990	0.000
D61.2 Aplastic anaemia due to other external agents	0.010	0.990	0.000
D61.1 Drug-induced aplastic anaemia	0.010	0.990	0.000
D61.0 Constitutional aplastic anaemia	0.010	0.990	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.009	0.990	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.009	0.990	0.000
D60.8 Other acquired pure red cell aplasias	0.009	0.990	0.000
D60.1 Transient acquired pure red cell aplasia	0.009	0.990	0.000
D60.0 Chronic acquired pure red cell aplasia	0.009	0.990	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.009	0.990	0.000
F38.8 Other specified mood [affective] disorders	0.009	0.990	0.000
F38.1 Other recurrent mood [affective] disorders	0.009	0.990	0.000
F38.0 Other single mood [affective] disorders	0.009	0.990	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.009	0.990	0.000
Q74 Other congenital malformations of limb(s)	0.009	0.991	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.009	0.991	0.000
Q66.7 Pes cavus	0.009	0.991	0.000
Q76 Congenital malformations of spine and bony thorax	0.009	0.991	0.000
Q24.8 Other specified congenital malformations of heart	0.009	0.991	0.000
Q78 Other osteochondrodysplasias	0.009	0.991	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.991	0.009
Q05 Spina bifida	0.009	0.991	0.000
D68 Other coagulation defects	0.002	0.991	0.007
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.009	0.991	0.000
F30.2 Mania with psychotic symptoms	0.009	0.991	0.000
D52.8 Other folate deficiency anaemias	0.009	0.991	0.000
D52.1 Drug-induced folate deficiency anaemia	0.009	0.991	0.000
D52.0 Dietary folate deficiency anaemia	0.009	0.991	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.009	0.991	0.000
Q84 Other congenital malformations of integument	0.009	0.991	0.000
Q81 Epidermolysis bullosa	0.009	0.991	0.000
Q80 Congenital ichthyosis	0.009	0.991	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.009	0.991	0.000
Q66.3 Other congenital varus deformities of feet	0.009	0.991	0.000
Q07 Other congenital malformations of nervous system	0.009	0.991	0.000
Q27 Other congenital malformations of peripheral vascular system	0.009	0.991	0.000
Q85 Phakomatoses, not elsewhere classified	0.009	0.991	0.000
Q35-Q37 Cleft lip and cleft palate	0.009	0.991	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.009	0.991	0.000
Q18 Other congenital malformations of face and neck	0.009	0.991	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.008	0.991	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.008	0.991	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.008	0.991	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.008	0.991	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.008	0.991	0.000
Q75 Other congenital malformations of skull and face bones	0.008	0.991	0.000
Q73 Reduction defects of unspecified limb	0.008	0.991	0.000
Q72 Reduction defects of lower limb	0.008	0.991	0.000
Q71 Reduction defects of upper limb	0.008	0.991	0.000
Q70 Syndactyly	0.008	0.991	0.000
Q69 Polydactyly	0.008	0.991	0.000
Q68 Other congenital musculoskeletal deformities	0.008	0.991	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.991	0.000
Q25 Congenital malformations of great arteries	0.008	0.991	0.000
Q83 Congenital malformations of breast	0.008	0.992	0.000
Q82 Other congenital malformations of skin	0.008	0.992	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.008	0.992	0.000
Q04 Other congenital malformations of brain	0.008	0.992	0.000
Q24.5 Malformation of coronary vessels	0.008	0.992	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.008	0.992	0.000
Q66.8 Other congenital deformities of feet	0.008	0.992	0.000
Q79.6 Ehlers-Danlos syndrome	0.008	0.992	0.000
Q05.9 Spina bifida, unspecified	0.008	0.992	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.008	0.992	0.000
Q24.0 Dextrocardia	0.008	0.992	0.000
Q12 Congenital lens malformations	0.008	0.992	0.000
Q06 Other congenital malformations of spinal cord	0.008	0.992	0.000
Q03 Congenital hydrocephalus	0.008	0.992	0.000
Q01 Encephalocele	0.008	0.992	0.000
Q00 Anencephaly and similar malformations	0.008	0.992	0.000
Q02 Microcephaly	0.008	0.992	0.000
Q66.9 Congenital deformity of feet, unspecified	0.008	0.992	0.000
Q66.6 Other congenital valgus deformities of feet	0.008	0.992	0.000
Q66.5 Congenital pes planus	0.008	0.992	0.000
Q66.4 Talipes calcaneovalgus	0.008	0.992	0.000
Q66.2 Metatarsus varus	0.008	0.992	0.000
Q66.1 Talipes calcaneovarus	0.008	0.992	0.000
Q66.0 Talipes equinovarus	0.008	0.992	0.000
Q89.9 Congenital malformation, unspecified	0.008	0.992	0.000
Q89.8 Other specified congenital malformations	0.008	0.992	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.008	0.992	0.000
Q89.4 Conjoined twins	0.008	0.992	0.000
Q89.3 Situs inversus	0.008	0.992	0.000
Q89.1 Congenital malformations of adrenal gland	0.008	0.992	0.000
Q89.0 Congenital malformations of spleen	0.008	0.992	0.000
Q60-Q64 Congenital malformations of the urinary system	0.008	0.992	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.008	0.992	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.008	0.992	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.008	0.992	0.000
Q26 Congenital malformations of great veins	0.008	0.992	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.008	0.992	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.008	0.992	0.000
Q43 Other congenital malformations of intestine	0.008	0.992	0.000
Q17 Other congenital malformations of ear	0.007	0.992	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.007	0.992	0.000
Q15 Other congenital malformations of eye	0.007	0.992	0.000
Q14 Congenital malformations of posterior segment of eye	0.007	0.992	0.000
Q13 Congenital malformations of anterior segment of eye	0.007	0.992	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.007	0.992	0.000
Q24.6 Congenital heart block	0.007	0.992	0.000
Q24.4 Congenital subaortic stenosis	0.007	0.992	0.000
Q24.3 Pulmonary infundibular stenosis	0.007	0.992	0.000
Q24.2 Cor triatriatum	0.007	0.992	0.000
Q24.1 Levocardia	0.007	0.992	0.000
Q78.0 Osteogenesis imperfecta	0.007	0.992	0.000
Q65 Congenital deformities of hip	0.007	0.993	0.000
Q07.0 Arnold-Chiari syndrome	0.007	0.993	0.000
Q50-Q56 Congenital malformations of genital organs	0.007	0.993	0.000
Q25.4 Other congenital malformations of aorta	0.007	0.993	0.000
Q27.3 Peripheral arteriovenous malformation	0.007	0.993	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.007	0.993	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.007	0.993	0.000
Q79.5 Other congenital malformations of abdominal wall	0.007	0.993	0.000
Q79.4 Prune belly syndrome	0.007	0.993	0.000
Q79.3 Gastroschisis	0.007	0.993	0.000
Q79.2 Exomphalos	0.007	0.993	0.000
Q79.1 Other congenital malformations of diaphragm	0.007	0.993	0.000
Q79.0 Congenital diaphragmatic hernia	0.007	0.993	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.007	0.993	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.007	0.993	0.000
Q74.3 Arthrogryposis multiplex congenita	0.007	0.993	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.007	0.993	0.000
Q74.1 Congenital malformation of knee	0.007	0.993	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.993	0.007
Q43.3 Congenital malformations of intestinal fixation	0.007	0.993	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.007	0.993	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.007	0.993	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.007	0.993	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.007	0.993	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.007	0.993	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.007	0.993	0.000
Q90 Down's syndrome	0.007	0.993	0.000
Q96 Turner's syndrome	0.007	0.993	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.007	0.993	0.000
Q76.8 Other congenital malformations of bony thorax	0.007	0.993	0.000
Q76.7 Congenital malformation of sternum	0.007	0.993	0.000
Q76.6 Other congenital malformations of ribs	0.007	0.993	0.000
Q76.5 Cervical rib	0.007	0.993	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.007	0.993	0.000
Q76.2 Congenital spondylolisthesis	0.007	0.993	0.000
Q76.1 Klippel-Feil syndrome	0.007	0.993	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.007	0.993	0.000
D68.6 Other Thrombophilia	0.001	0.993	0.006
Q27.8 Other specified congenital malformations of peripheral vascular system	0.007	0.993	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.007	0.993	0.000
Q78.8 Other specified osteochondrodysplasias	0.007	0.993	0.000
Q78.6 Multiple congenital exostoses	0.007	0.993	0.000
Q78.5 Metaphyseal dysplasia	0.007	0.993	0.000
Q78.4 Enchondromatosis	0.007	0.993	0.000
Q78.3 Progressive diaphyseal dysplasia	0.007	0.993	0.000
Q78.2 Osteopetrosis	0.007	0.993	0.000
Q78.1 Polyostotic fibrous dysplasia	0.007	0.993	0.000
Q04.6 Congenital cerebral cysts	0.007	0.993	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.007	0.993	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.993	0.007
Q05.8 Sacral spina bifida without hydrocephalus	0.007	0.993	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.007	0.993	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.007	0.993	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.007	0.993	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.007	0.993	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.007	0.993	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.007	0.993	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.007	0.993	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.007	0.993	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.007	0.993	0.000
Q23 Congenital malformations of aortic and mitral valves	0.007	0.993	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.007	0.993	0.000
Q80.9 Congenital ichthyosis, unspecified	0.006	0.993	0.000
Q80.8 Other congenital ichthyosis	0.006	0.993	0.000
Q80.4 Harlequin foetus	0.006	0.993	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.006	0.993	0.000
Q80.2 Lamellar ichthyosis	0.006	0.993	0.000
Q80.1 X-linked ichthyosis	0.006	0.993	0.000
Q80.0 Ichthyosis vulgaris	0.006	0.993	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.006	0.993	0.000
Q81.8 Other epidermolysis bullosa	0.006	0.993	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.006	0.993	0.000
Q81.1 Epidermolysis bullosa letalis	0.006	0.993	0.000
Q81.0 Epidermolysis bullosa simplex	0.006	0.993	0.000
Q82.5 Congenital nonneoplastic naevus	0.006	0.993	0.000
Q84.9 Congenital malformation of integument, unspecified	0.006	0.993	0.000
Q84.8 Other specified congenital malformations of integument	0.006	0.993	0.000
Q84.6 Other congenital malformations of nails	0.006	0.993	0.000
Q84.5 Enlarged and hypertrophic nails	0.006	0.993	0.000
Q84.4 Congenital leukonychia	0.006	0.993	0.000
Q84.3 Anonychia	0.006	0.993	0.000
Q84.2 Other congenital malformations of hair	0.006	0.993	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.006	0.993	0.000
Q84.0 Congenital alopecia	0.006	0.993	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.006	0.993	0.000
Q86.2 Dysmorphism due to warfarin	0.006	0.993	0.000
Q86.1 Foetal hydantoin syndrome	0.006	0.993	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.006	0.993	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.006	0.993	0.000
D68.2 Hereditary deficiency of other clotting factors	0.001	0.993	0.006
Q07.9 Congenital malformation of nervous system, unspecified	0.006	0.993	0.000
Q07.8 Other specified congenital malformations of nervous system	0.006	0.993	0.000
Q27.4 Congenital phlebectasia	0.006	0.993	0.000
Q27.2 Other congenital malformations of renal artery	0.006	0.993	0.000
Q27.1 Congenital renal artery stenosis	0.006	0.993	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.006	0.993	0.000
Q85.1 Tuberous sclerosis	0.006	0.993	0.000
Q34 Other congenital malformations of respiratory system	0.006	0.993	0.000
Q33 Congenital malformations of lung	0.006	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations