TreeWAS – Variant ID: rs117141652

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
R50-R69 General symptoms and signs	0.997	0.003	0.000
Chapter XI Diseases of the digestive system	0.997	0.003	0.000
O00-O08 Pregnancy with abortive outcome	0.996	0.004	0.000
M20-M25 Other joint disorders	0.995	0.005	0.000
R69 Unknown and unspecified causes of morbidity	0.994	0.006	0.000
Chapter V Mental and behavioural disorders	0.992	0.008	0.000
Chapter VI Diseases of the nervous system	0.988	0.012	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.985	0.015	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.985	0.015	0.000
Chapter XX External causes of morbidity and mortality	0.978	0.022	0.000
Chapter VIII Diseases of the ear and mastoid process	0.977	0.023	0.000
F41 Other anxiety disorders	0.968	0.032	0.000
K55-K64 Other diseases of intestines	0.965	0.035	0.000
O60-O75 Complications of labour and delivery	0.962	0.038	0.000
O04 Medical abortion	0.962	0.038	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.956	0.044	0.000
D60-D64 Aplastic and other anaemias	0.953	0.047	0.000
S60-S69 Injuries to the wrist and hand	0.951	0.049	0.000
F41.9 Anxiety disorder, unspecified	0.947	0.053	0.000
G90-G99 Other disorders of the nervous system	0.942	0.058	0.000
O03 Spontaneous abortion	0.941	0.059	0.000
D64 Other anaemias	0.940	0.060	0.000
O04.9 Complete or unspecified, without complication	0.938	0.062	0.000
M25 Other joint disorders, not elsewhere classified	0.937	0.063	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.937	0.063	0.000
K59 Other functional intestinal disorders	0.931	0.069	0.000
D50-D53 Nutritional anaemias	0.930	0.070	0.000
D64.9 Anaemia, unspecified	0.930	0.070	0.000
K90-K93 Other diseases of the digestive system	0.925	0.075	0.000
K20 Oesophagitis	0.925	0.075	0.000
H90-H95 Other disorders of ear	0.924	0.076	0.000
R63 Symptoms and signs concerning food and fluid intake	0.922	0.078	0.000
K62 Other diseases of anus and rectum	0.910	0.090	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.908	0.092	0.000
K59.0 Constipation	0.902	0.098	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.898	0.102	0.000
S61 Open wound of wrist and hand	0.897	0.103	0.000
D50 Iron deficiency anaemia	0.895	0.105	0.000
O03.4 Incomplete, without complication	0.894	0.106	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.892	0.108	0.000
M34 Systemic sclerosis	0.891	0.109	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.889	0.111	0.000
M80-M85 Disorders of bone density and structure	0.886	0.114	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.880	0.120	0.000
Chapter IX Diseases of the circulatory system	0.877	0.123	0.000
M65-M68 Disorders of synovium and tendon	0.877	0.123	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.876	0.124	0.000
M35 Other systemic involvement of connective tissue	0.875	0.125	0.000
F41.2 Mixed anxiety and depressive disorder	0.871	0.129	0.000
K62.8 Other specified diseases of anus and rectum	0.870	0.130	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.870	0.130	0.000
K70-K77 Diseases of liver	0.869	0.131	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.869	0.131	0.000
O72 Postpartum haemorrhage	0.867	0.133	0.000
T66-T78 Other and unspecified effects of external causes	0.864	0.136	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.862	0.138	0.000
M24 Other specific joint derangements	0.862	0.138	0.000
K29 Gastritis and duodenitis	0.860	0.140	0.000
H60-H62 Diseases of external ear	0.860	0.140	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.856	0.144	0.000
O02 Other abnormal products of conception	0.856	0.144	0.000
F43 Reaction to severe stress, and adjustment disorders	0.855	0.144	0.000
H92 Otalgia and effusion of ear	0.855	0.145	0.000
Chapter X Diseases of the respiratory system	0.854	0.146	0.000
R50 Fever of unknown origin	0.849	0.151	0.000
I95 Hypotension	0.849	0.151	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.849	0.151	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.847	0.153	0.000
W20-W49 Exposure to inanimate mechanical forces	0.846	0.154	0.000
M25.5 Pain in joint	0.845	0.155	0.000
R13 Dysphagia	0.844	0.156	0.000
K29.6 Other gastritis	0.843	0.157	0.000
G95 Other diseases of spinal cord	0.842	0.158	0.000
I30-I52 Other forms of heart disease	0.839	0.161	0.000
R42 Dizziness and giddiness	0.839	0.161	0.000
T39.1 4-Aminophenol derivatives	0.838	0.162	0.000
M45-M49 Spondylopathies	0.837	0.163	0.000
R59 Enlarged lymph nodes	0.836	0.164	0.000
K92 Other diseases of digestive system	0.836	0.164	0.000
R63.4 Abnormal weight loss	0.835	0.165	0.000
I95.1 Orthostatic hypotension	0.834	0.166	0.000
K62.3 Rectal prolapse	0.834	0.166	0.000
G93 Other disorders of brain	0.833	0.167	0.000
I51 Complications and ill-defined descriptions of heart disease	0.833	0.167	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.833	0.167	0.000
S50-S59 Injuries to the elbow and forearm	0.832	0.168	0.000
G70-G73 Diseases of myoneural junction and muscle	0.829	0.171	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.828	0.172	0.000
D50.9 Iron deficiency anaemia, unspecified	0.827	0.173	0.000
I51.7 Cardiomegaly	0.824	0.176	0.000
G20-G26 Extrapyramidal and movement disorders	0.819	0.181	0.000
M86-M90 Other osteopathies	0.818	0.182	0.000
M65 Synovitis and tenosynovitis	0.815	0.185	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.815	0.185	0.000
J30-J39 Other diseases of upper respiratory tract	0.815	0.185	0.000
K21 Gastro-oesophageal reflux disease	0.814	0.186	0.000
M23 Internal derangement of knee	0.811	0.188	0.000
H80-H83 Diseases of inner ear	0.811	0.189	0.000
K25 Gastric ulcer	0.810	0.190	0.000
M22 Disorders of patella	0.808	0.192	0.000
O00 Ectopic pregnancy	0.808	0.192	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.807	0.193	0.000
K56.6 Other and unspecified intestinal obstruction	0.803	0.197	0.000
T79-T79 Certain early complications of trauma	0.802	0.198	0.000
K62.9 Disease of anus and rectum, unspecified	0.802	0.198	0.000
S61.8 Open wound of other parts of wrist and hand	0.802	0.198	0.000
S40-S49 Injuries to the shoulder and upper arm	0.801	0.199	0.000
O72.1 Other immediate postpartum haemorrhage	0.799	0.201	0.000
R12 Heartburn	0.798	0.202	0.000
M31 Other necrotising vasculopathies	0.797	0.203	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.796	0.204	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.794	0.206	0.000
M21 Other acquired deformities of limbs	0.794	0.206	0.000
D50.8 Other iron deficiency anaemias	0.794	0.206	0.000
X60-X84 Intentional self-harm	0.793	0.207	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.792	0.208	0.000
F42 Obsessive-compulsive disorder	0.789	0.211	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.788	0.212	0.000
M35.0 Sicca syndrome [Sjogren]	0.786	0.214	0.000
K70 Alcoholic liver disease	0.786	0.214	0.000
G40-G47 Episodic and paroxysmal disorders	0.785	0.215	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.782	0.218	0.000
S61.0 Open wound of finger(s) without damage to nail	0.781	0.219	0.000
S68 Traumatic amputation of wrist and hand	0.781	0.219	0.000
S90-S99 Injuries to the ankle and foot	0.780	0.220	0.000
G96 Other disorders of central nervous system	0.777	0.223	0.000
F99-F99 Unspecified mental disorder	0.772	0.227	0.000
H61 Other disorders of external ear	0.771	0.229	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.770	0.230	0.000
H93 Other disorders of ear, not elsewhere classified	0.770	0.230	0.000
M25.51 Pain in joint (Shoulder region)	0.769	0.231	0.000
M47 Spondylosis	0.769	0.231	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.769	0.231	0.000
O85-O92 Complications predominantly related to the puerperium	0.769	0.231	0.000
T78 Adverse effects, not elsewhere classified	0.766	0.234	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.764	0.236	0.000
K65-K67 Diseases of peritoneum	0.763	0.237	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.762	0.238	0.000
S62 Fracture at wrist and hand level	0.761	0.239	0.000
S32 Fracture of lumbar spine and pelvis	0.760	0.240	0.000
J00-J06 Acute upper respiratory infections	0.759	0.240	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.759	0.241	0.000
H92.0 Otalgia	0.759	0.241	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.759	0.241	0.000
M34.9 Systemic sclerosis, unspecified	0.758	0.242	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.757	0.243	0.000
M05-M14 Inflammatory polyarthropathies	0.755	0.245	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.755	0.245	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.752	0.248	0.000
F45 Somatoform disorders	0.751	0.249	0.000
M00-M03 Infectious arthropathies	0.750	0.250	0.000
R63.0 Anorexia	0.750	0.250	0.000
M34.1 CR(E)ST syndrome	0.749	0.251	0.000
R14 Flatulence and related conditions	0.749	0.251	0.000
G40 Epilepsy	0.748	0.252	0.000
M25.7 Osteophyte	0.748	0.252	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.747	0.253	0.000
D55-D59 Haemolytic anaemias	0.746	0.254	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.746	0.254	0.000
O42 Premature rupture of membranes	0.745	0.255	0.000
M24.1 Other articular cartilage disorders	0.744	0.256	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.743	0.257	0.000
K61 Abscess of anal and rectal regions	0.742	0.257	0.000
F43.0 Acute stress reaction	0.742	0.258	0.000
M81 Osteoporosis without pathological fracture	0.742	0.258	0.000
F60-F69 Disorders of adult personality and behaviour	0.741	0.259	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.741	0.259	0.000
V80-V89 Other land transport accidents	0.740	0.260	0.000
Chapter XXII Codes for special purposes	0.739	0.260	0.000
F41.1 Generalised anxiety disorder	0.739	0.261	0.000
S70-S79 Injuries to the hip and thigh	0.739	0.261	0.000
K92.1 Melaena	0.738	0.261	0.000
O63 Long labour	0.738	0.262	0.000
R51 Headache	0.738	0.262	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.738	0.262	0.000
R15 Faecal incontinence	0.734	0.266	0.000
M91-M94 Chondropathies	0.733	0.267	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.733	0.267	0.000
R61 Hyperhidrosis	0.730	0.270	0.000
H92.1 Otorrhoea	0.729	0.271	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.729	0.271	0.000
O48 Prolonged pregnancy	0.729	0.271	0.000
F40 Phobic anxiety disorders	0.728	0.272	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.727	0.273	0.000
O02.1 Missed abortion	0.726	0.274	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.726	0.274	0.000
O62 Abnormalities of forces of labour	0.724	0.276	0.000
K75 Other inflammatory liver diseases	0.720	0.280	0.000
R47-R49 Symptoms and signs involving speech and voice	0.720	0.280	0.000
O03.9 Complete or unspecified, without complication	0.719	0.281	0.000
Y43 Primarily systemic agents	0.719	0.281	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.718	0.282	0.000
G61 Inflammatory polyneuropathy	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.717	0.283	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.284	0.000
S10-S19 Injuries to the neck	0.716	0.284	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.716	0.284	0.000
M60-M63 Disorders of muscles	0.716	0.284	0.000
K59.8 Other specified functional intestinal disorders	0.716	0.284	0.000
G93.3 Postviral fatigue syndrome	0.716	0.284	0.000
G70 Myasthenia gravis and other myoneural disorders	0.715	0.285	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.715	0.285	0.000
R62 Lack of expected normal physiological development	0.715	0.285	0.000
R57 Shock, not elsewhere classified	0.715	0.285	0.000
R64 Cachexia	0.715	0.285	0.000
R58 Haemorrhage, not elsewhere classified	0.715	0.285	0.000
I51.9 Heart disease, unspecified	0.715	0.285	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.714	0.286	0.000
O07 Failed attempted abortion	0.714	0.286	0.000
O06 Unspecified abortion	0.714	0.286	0.000
O05 Other abortion	0.714	0.286	0.000
O01 Hydatidiform mole	0.714	0.286	0.000
W00-W19 Falls	0.714	0.286	0.000
G95.9 Disease of spinal cord, unspecified	0.714	0.286	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.713	0.287	0.000
M33 Dermatopolymyositis	0.713	0.287	0.000
M32 Systemic lupus erythematosus	0.713	0.287	0.000
M30 Polyarteritis nodosa and related conditions	0.713	0.287	0.000
R87 Abnormal findings in specimens from female genital organs	0.713	0.287	0.000
J34 Other disorders of nose and nasal sinuses	0.711	0.289	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.711	0.289	0.000
F80-F89 Disorders of psychological development	0.711	0.289	0.000
F70-F79 Mental retardation	0.711	0.289	0.000
R50.8 Other specified fever	0.710	0.290	0.000
G40.9 Epilepsy, unspecified	0.709	0.291	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.709	0.291	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.709	0.291	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.709	0.291	0.000
R56 Convulsions, not elsewhere classified	0.708	0.292	0.000
R23 Other skin changes	0.708	0.292	0.000
K70.9 Alcoholic liver disease, unspecified	0.708	0.292	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.708	0.292	0.000
F48 Other neurotic disorders	0.706	0.293	0.000
F44 Dissociative [conversion] disorders	0.706	0.293	0.000
R11 Nausea and vomiting	0.706	0.294	0.000
K59.9 Functional intestinal disorder, unspecified	0.705	0.295	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.704	0.296	0.000
R54 Senility	0.703	0.296	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.703	0.297	0.000
K22 Other diseases of oesophagus	0.703	0.297	0.000
H91 Other hearing loss	0.702	0.298	0.000
F43.1 Posttraumatic stress disorder	0.702	0.298	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.701	0.298	0.000
Y35-Y36 Legal intervention and operations of war	0.701	0.298	0.000
Y10-Y34 Event of undetermined intent	0.701	0.298	0.000
Y00-Y09 Assault	0.701	0.298	0.000
X85-X99 Assault	0.701	0.298	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.701	0.298	0.000
X50-X57 Overexertion, travel and privation	0.701	0.298	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.701	0.298	0.000
X30-X39 Exposure to forces of nature	0.701	0.298	0.000
X20-X29 Contact with venomous animals and plants	0.701	0.298	0.000
X10-X19 Contact with heat and hot substances	0.701	0.298	0.000
X00-X09 Exposure to smoke, fire and flames	0.701	0.298	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.701	0.298	0.000
W75-W84 Other accidental threats to breathing	0.701	0.298	0.000
W65-W74 Accidental drowning and submersion	0.701	0.298	0.000
W50-W64 Exposure to animate mechanical forces	0.701	0.298	0.000
V98-V99 Other and unspecified transport accidents	0.701	0.298	0.000
V95-V97 Air and space transport accidents	0.701	0.298	0.000
V90-V94 Water transport accidents	0.701	0.298	0.000
V70-V79 Bus occupant injured in transport accident	0.701	0.298	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.701	0.298	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.701	0.298	0.000
V40-V49 Car occupant injured in transport accident	0.701	0.298	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.701	0.298	0.000
V20-V29 Motorcycle rider injured in transport accident	0.701	0.298	0.000
V01-V09 Pedestrian injured in transport accident	0.701	0.298	0.000
T39.0 Salicylates	0.701	0.299	0.000
K27 Peptic ulcer, site unspecified	0.701	0.299	0.000
R25 Abnormal involuntary movements	0.700	0.300	0.000
G20 Parkinson's disease	0.698	0.301	0.000
M84 Disorders of continuity of bone	0.697	0.303	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.697	0.303	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.696	0.304	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.695	0.305	0.000
F41.8 Other specified anxiety disorders	0.694	0.306	0.000
F41.3 Other mixed anxiety disorders	0.694	0.306	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.694	0.306	0.000
D80-D89 Certain disorders involving the immune mechanism	0.693	0.307	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.692	0.308	0.000
R45 Symptoms and signs involving emotional state	0.692	0.308	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.692	0.308	0.000
J35 Chronic diseases of tonsils and adenoids	0.691	0.309	0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.691	0.309	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.690	0.310	0.000
O74 Complications of anaesthesia during labour and delivery	0.690	0.310	0.000
O73 Retained placenta and membranes, without haemorrhage	0.690	0.310	0.000
O71 Other obstetric trauma	0.690	0.310	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.690	0.310	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.690	0.310	0.000
O61 Failed induction of labour	0.690	0.310	0.000
O60 Preterm delivery	0.690	0.310	0.000
S20-S29 Injuries to the thorax	0.690	0.310	0.000
W22 Striking against or struck by other objects	0.690	0.310	0.000
I05-I09 Chronic rheumatic heart diseases	0.690	0.310	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.690	0.310	0.000
O04.7 Complete or unspecified, complicated by embolism	0.690	0.310	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.690	0.310	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.690	0.310	0.000
O04.4 Incomplete, without complication	0.690	0.310	0.000
O04.3 Incomplete, with other and unspecified complications	0.690	0.310	0.000
O04.2 Incomplete, complicated by embolism	0.690	0.310	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.690	0.310	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.690	0.310	0.000
I95.2 Hypotension due to drugs	0.690	0.310	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.689	0.311	0.000
K29.4 Chronic atrophic gastritis	0.688	0.312	0.000
K58 Irritable bowel syndrome	0.687	0.313	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.687	0.313	0.000
K90 Intestinal malabsorption	0.687	0.313	0.000
Y52 Agents primarily affecting the cardiovascular system	0.686	0.314	0.000
K28 Gastrojejunal ulcer	0.685	0.315	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.685	0.315	0.000
M87 Osteonecrosis	0.684	0.315	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.684	0.316	0.000
R59.0 Localised enlarged lymph nodes	0.683	0.317	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.683	0.317	0.000
D62 Acute posthaemorrhagic anaemia	0.683	0.317	0.000
S69 Other and unspecified injuries of wrist and hand	0.682	0.318	0.000
S67 Crushing injury of wrist and hand	0.682	0.318	0.000
S65 Injury of blood vessels at wrist and hand level	0.682	0.318	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.682	0.318	0.000
S60 Superficial injury of wrist and hand	0.682	0.318	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.681	0.319	0.000
M80 Osteoporosis with pathological fracture	0.680	0.319	0.000
G95.2 Cord compression, unspecified	0.679	0.321	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.679	0.321	0.000
S61.1 Open wound of finger(s) with damage to nail	0.679	0.321	0.000
H61.0 Perichondritis of external ear	0.678	0.322	0.000
G93.9 Disorder of brain, unspecified	0.678	0.322	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.676	0.324	0.000
M47.9 Spondylosis, unspecified	0.675	0.325	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.675	0.325	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.675	0.325	0.000
G90 Disorders of autonomic nervous system	0.675	0.325	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.675	0.325	0.000
G92 Toxic encephalopathy	0.675	0.325	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.675	0.325	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.675	0.325	0.000
O03.7 Complete or unspecified, complicated by embolism	0.675	0.325	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.675	0.325	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.675	0.325	0.000
O03.3 Incomplete, with other and unspecified complications	0.675	0.325	0.000
O03.2 Incomplete, complicated by embolism	0.675	0.325	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.675	0.325	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.675	0.325	0.000
D52 Folate deficiency anaemia	0.674	0.326	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.674	0.326	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.674	0.326	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.674	0.326	0.000
D64.8 Other specified anaemias	0.674	0.326	0.000
D64.4 Congenital dyserythropoietic anaemia	0.674	0.326	0.000
D64.3 Other sideroblastic anaemias	0.674	0.326	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.674	0.326	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.674	0.326	0.000
D64.0 Hereditary sideroblastic anaemia	0.674	0.326	0.000
M40-M43 Deforming dorsopathies	0.673	0.327	0.000
Y44 Agents primarily affecting blood constituents	0.673	0.327	0.000
S51 Open wound of forearm	0.673	0.327	0.000
O66 Other obstructed labour	0.672	0.327	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.672	0.328	0.000
O00.1 Tubal pregnancy	0.672	0.328	0.000
O40 Polyhydramnios	0.672	0.328	0.000
M25.9 Joint disorder, unspecified	0.672	0.328	0.000
M25.8 Other specified joint disorders	0.672	0.328	0.000
M25.3 Other instability of joint	0.672	0.328	0.000
M25.2 Flail joint	0.672	0.328	0.000
M25.1 Fistula of joint	0.672	0.328	0.000
M25.0 Haemarthrosis	0.672	0.328	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.672	0.328	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.672	0.328	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.672	0.328	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.672	0.328	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.672	0.328	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.672	0.328	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.672	0.328	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.672	0.328	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.672	0.328	0.000
T36 Poisoning by systemic antibiotics	0.672	0.328	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.670	0.330	0.000
K25.4 Chronic or unspecified with haemorrhage	0.669	0.331	0.000
O70 Perineal laceration during delivery	0.669	0.331	0.000
K59.4 Anal spasm	0.668	0.332	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.668	0.332	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.668	0.332	0.000
D53 Other nutritional anaemias	0.667	0.333	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.666	0.334	0.000
O44 Placenta praevia	0.666	0.334	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.666	0.334	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.666	0.334	0.000
M24.0 Loose body in joint	0.666	0.334	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.665	0.334	0.000
W25 Contact with sharp glass	0.665	0.335	0.000
R68 Other general symptoms and signs	0.664	0.335	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.664	0.336	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.663	0.336	0.000
K62.7 Radiation proctitis	0.663	0.337	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.663	0.337	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.663	0.337	0.000
J30 Vasomotor and allergic rhinitis	0.662	0.338	0.000
K50-K52 Noninfective enteritis and colitis	0.662	0.338	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.661	0.339	0.000
R63.6 Insufficient intake of food and water due to self neglect	0.661	0.339	0.000
R63.5 Abnormal weight gain	0.661	0.339	0.000
R63.3 Feeding difficulties and mismanagement	0.661	0.339	0.000
R63.2 Polyphagia	0.661	0.339	0.000
R63.1 Polydipsia	0.661	0.339	0.000
M23.5 Chronic instability of knee	0.660	0.340	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.660	0.340	0.000
H93.1 Tinnitus	0.660	0.340	0.000
O42.9 Premature rupture of membranes, unspecified	0.659	0.341	0.000
K59.1 Functional diarrhoea	0.659	0.341	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.659	0.341	0.000
M85 Other disorders of bone density and structure	0.659	0.341	0.000
R50.0 Fever with chills	0.659	0.341	0.000
V10-V19 Pedal cyclist injured in transport accident	0.659	0.341	0.000
G96.0 Cerebrospinal fluid leak	0.659	0.341	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.659	0.341	0.000
I45 Other conduction disorders	0.658	0.342	0.000
Y57 Other and unspecified drugs and medicaments	0.657	0.343	0.000
G30-G32 Other degenerative diseases of the nervous system	0.657	0.343	0.000
K22.7 Barrett's oesophagus	0.655	0.345	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.655	0.345	0.000
M31.6 Other giant cell arteritis	0.654	0.345	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.654	0.346	0.001
S52 Fracture of forearm	0.654	0.346	0.000
G83 Other paralytic syndromes	0.654	0.346	0.000
K56.7 Ileus, unspecified	0.654	0.346	0.000
R59.9 Enlarged lymph nodes, unspecified	0.654	0.346	0.000
J09-J18 Influenza and pneumonia	0.653	0.347	0.000
K29.8 Duodenitis	0.653	0.347	0.000
M50-M54 Other dorsopathies	0.653	0.347	0.000
K62.2 Anal prolapse	0.652	0.347	0.000
K62.6 Ulcer of anus and rectum	0.651	0.349	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.651	0.349	0.000
W44 Foreign body entering into or through eye or natural orifice	0.649	0.351	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.648	0.352	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.648	0.352	0.000
K25.7 Chronic without haemorrhage or perforation	0.648	0.352	0.000
G95.8 Other specified diseases of spinal cord	0.648	0.352	0.000
J32 Chronic sinusitis	0.647	0.353	0.000
J31.0 Chronic rhinitis	0.646	0.354	0.000
G91 Hydrocephalus	0.645	0.355	0.000
H81 Disorders of vestibular function	0.645	0.355	0.000
D61 Other aplastic anaemias	0.644	0.356	0.000
R46 Symptoms and signs involving appearance and behaviour	0.644	0.356	0.000
R43 Disturbances of smell and taste	0.644	0.356	0.000
I36 Nonrheumatic tricuspid valve disorders	0.643	0.356	0.000
H80 Otosclerosis	0.643	0.357	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.643	0.357	0.000
S61.7 Multiple open wounds of wrist and hand	0.643	0.357	0.000
M21.1 Varus deformity, not elsewhere classified	0.643	0.357	0.000
D50.1 Sideropenic dysphagia	0.642	0.358	0.000
M47.2 Other spondylosis with radiculopathy	0.641	0.359	0.000
G62 Other polyneuropathies	0.641	0.359	0.000
K25.3 Acute without haemorrhage or perforation	0.641	0.359	0.000
T82.3 Mechanical complication of other vascular grafts	0.640	0.359	0.000
H65-H75 Diseases of middle ear and mastoid	0.640	0.360	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.639	0.361	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.639	0.361	0.000
T39.4 Antirheumatics, not elsewhere classified	0.639	0.361	0.000
T39.2 Pyrazolone derivatives	0.639	0.361	0.000
M34.8 Other forms of systemic sclerosis	0.639	0.361	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.639	0.361	0.000
M34.0 Progressive systemic sclerosis	0.639	0.361	0.000
H90 Conductive and sensorineural hearing loss	0.639	0.361	0.000
M81.9 Osteoporosis, unspecified	0.638	0.362	0.000
T87 Complications peculiar to reattachment and amputation	0.637	0.363	0.000
T86 Failure and rejection of transplanted organs and tissues	0.637	0.363	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.637	0.363	0.000
T78.3 Angioneurotic oedema	0.637	0.363	0.000
M23.4 Loose body in knee	0.636	0.364	0.000
Y83.4 Other reconstructive surgery	0.636	0.364	0.000
I47 Paroxysmal tachycardia	0.635	0.364	0.000
M83 Adult osteomalacia	0.635	0.365	0.000
M82 Osteoporosis in diseases classified elsewhere	0.635	0.365	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.635	0.365	0.000
J60-J70 Lung diseases due to external agents	0.635	0.365	0.000
S62.6 Fracture of other finger	0.634	0.366	0.000
M35.3 Polymyalgia rheumatica	0.634	0.366	0.000
D51 Vitamin B12 deficiency anaemia	0.633	0.366	0.000
Chapter VII Diseases of the eye and adnexa	0.634	0.366	0.000
G70.0 Myasthenia gravis	0.633	0.367	0.000
K72 Hepatic failure, not elsewhere classified	0.633	0.367	0.000
K59.3 Megacolon, not elsewhere classified	0.633	0.367	0.000
M23.3 Other meniscus derangements	0.632	0.368	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.632	0.368	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.632	0.368	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations