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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117209336
log Bayes Factor = 10.1195
Chromosome 15   position 32,945,748  (GRCh37) Explore rs117209336 on Ensembl!
Variant rs117209336 is part of Cluster X0185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
M19.9 Arthrosis, unspecified
1.000 0.000 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K62 Other diseases of anus and rectum
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
M19 Other arthrosis
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
M15-M19 Arthrosis
0.998 0.002 0.000
M51 Other intervertebral disk disorders
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
M51.2 Other specified intervertebral disk displacement
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
K58 Irritable bowel syndrome
0.990 0.010 0.000
S60-S69 Injuries to the wrist and hand
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
K62.5 Haemorrhage of anus and rectum
0.987 0.013 0.000
K57 Diverticular disease of intestine
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.983 0.017 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.982 0.018 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.981 0.019 0.000
I51 Complications and ill-defined descriptions of heart disease
0.973 0.027 0.000
I20-I25 Ischaemic heart diseases
0.963 0.037 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.949 0.051 0.000
I25 Chronic ischaemic heart disease
0.943 0.057 0.000
I25.2 Old myocardial infarction
0.938 0.062 0.000
I51.8 Other ill-defined heart diseases
0.938 0.062 0.000
K61 Abscess of anal and rectal regions
0.938 0.062 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.936 0.064 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.927 0.073 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.924 0.076 0.000
S62 Fracture at wrist and hand level
0.924 0.076 0.000
K86 Other diseases of pancreas
0.922 0.078 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.921 0.079 0.000
K62.4 Stenosis of anus and rectum
0.919 0.081 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.918 0.082 0.000
K62.8 Other specified diseases of anus and rectum
0.915 0.085 0.000
K60 Fissure and fistula of anal and rectal regions
0.914 0.086 0.000
I42 Cardiomyopathy
0.907 0.093 0.000
S64 Injury of nerves at wrist and hand level
0.906 0.094 0.000
M79.8 Other specified soft tissue disorders
0.904 0.096 0.000
E20-E35 Disorders of other endocrine glands
0.895 0.105 0.000
M40-M43 Deforming dorsopathies
0.892 0.108 0.000
K61.0 Anal abscess
0.888 0.112 0.000
K59 Other functional intestinal disorders
0.880 0.120 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.879 0.121 0.000
I33 Acute and subacute endocarditis
0.877 0.123 0.000
Chapter VI Diseases of the nervous system
0.869 0.131 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.867 0.133 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.866 0.134 0.000
K86.1 Other chronic pancreatitis
0.864 0.136 0.000
M54 Dorsalgia
0.855 0.145 0.000
E23 Hypofunction and other disorders of pituitary gland
0.855 0.145 0.000
M19.98 Arthrosis, unspecified (Other)
0.851 0.149 0.000
I35 Nonrheumatic aortic valve disorders
0.851 0.149 0.000
K62.3 Rectal prolapse
0.848 0.152 0.000
E50-E64 Other nutritional deficiencies
0.848 0.152 0.000
I46 Cardiac arrest
0.847 0.153 0.000
K62.1 Rectal polyp
0.847 0.153 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.843 0.157 0.000
M79.0 Rheumatism, unspecified
0.843 0.157 0.000
S62.3 Fracture of other metacarpal bone
0.838 0.162 0.000
S90-S99 Injuries to the ankle and foot
0.838 0.162 0.000
T66-T78 Other and unspecified effects of external causes
0.835 0.165 0.000
M65-M68 Disorders of synovium and tendon
0.835 0.165 0.000
M45-M49 Spondylopathies
0.835 0.165 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.833 0.167 0.000
I51.9 Heart disease, unspecified
0.828 0.172 0.000
I42.2 Other hypertrophic cardiomyopathy
0.822 0.178 0.000
K62.9 Disease of anus and rectum, unspecified
0.822 0.178 0.000
K86.8 Other specified diseases of pancreas
0.821 0.179 0.000
M50 Cervical disk disorders
0.816 0.184 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.816 0.184 0.000
I73 Other peripheral vascular diseases
0.815 0.185 0.000
I21 Acute myocardial infarction
0.814 0.186 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.814 0.186 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.812 0.188 0.000
S64.4 Injury of digital nerve of other finger
0.812 0.188 0.000
M41 Scoliosis
0.812 0.188 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.810 0.189 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.803 0.197 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.802 0.198 0.000
I25.1 Atherosclerotic heart disease
0.799 0.201 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.799 0.201 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.797 0.203 0.000
I33.0 Acute and subacute infective endocarditis
0.797 0.203 0.000
K86.9 Disease of pancreas, unspecified
0.796 0.204 0.000
I95 Hypotension
0.796 0.204 0.000
K59.1 Functional diarrhoea
0.793 0.207 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.791 0.209 0.000
K59.8 Other specified functional intestinal disorders
0.790 0.210 0.000
K55 Vascular disorders of intestine
0.788 0.212 0.000
M75 Shoulder lesions
0.788 0.212 0.000
M19.0 Primary arthrosis of other joints
0.787 0.213 0.000
T79-T79 Certain early complications of trauma
0.786 0.214 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.786 0.214 0.000
E23.0 Hypopituitarism
0.785 0.215 0.000
M54.5 Low back pain
0.784 0.216 0.000
K83 Other diseases of biliary tract
0.783 0.217 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.780 0.220 0.000
I42.9 Cardiomyopathy, unspecified
0.778 0.222 0.000
M60-M63 Disorders of muscles
0.777 0.223 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.777 0.223 0.000
I51.7 Cardiomegaly
0.777 0.223 0.000
M76 Enthesopathies of lower limb, excluding foot
0.776 0.223 0.000
I46.0 Cardiac arrest with successful resuscitation
0.776 0.224 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.774 0.226 0.000
M79.1 Myalgia
0.774 0.226 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.774 0.226 0.000
I44 Atrioventricular and left bundle-branch block
0.772 0.228 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.772 0.228 0.000
I73.9 Peripheral vascular disease, unspecified
0.772 0.228 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.767 0.233 0.000
I78 Diseases of capillaries
0.766 0.234 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.766 0.234 0.000
Chapter VIII Diseases of the ear and mastoid process
0.766 0.234 0.000
M77 Other enthesopathies
0.766 0.234 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.764 0.236 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.764 0.236 0.000
K60.3 Anal fistula
0.763 0.237 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
S62.5 Fracture of thumb
0.757 0.242 0.000
S69 Other and unspecified injuries of wrist and hand
0.755 0.245 0.000
M41.9 Scoliosis, unspecified
0.755 0.245 0.000
K85 Acute pancreatitis
0.755 0.245 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.755 0.245 0.000
G70-G73 Diseases of myoneural junction and muscle
0.753 0.247 0.000
G90-G99 Other disorders of the nervous system
0.750 0.250 0.000
I95.2 Hypotension due to drugs
0.750 0.250 0.000
M00-M03 Infectious arthropathies
0.747 0.253 0.000
M50.1 Cervical disk disorder with radiculopathy
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.747 0.253 0.000
K60.5 Anorectal fistula
0.743 0.257 0.000
E53 Deficiency of other B group vitamins
0.743 0.257 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.741 0.259 0.000
I99 Other and unspecified disorders of circulatory system
0.741 0.259 0.000
L60-L75 Disorders of skin appendages
0.739 0.261 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.738 0.262 0.000
S70-S79 Injuries to the hip and thigh
0.737 0.262 0.000
K60.1 Chronic anal fissure
0.735 0.265 0.000
M54.59 Low back pain (Site unspecified)
0.734 0.266 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.733 0.267 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.733 0.267 0.000
E16 Other disorders of pancreatic internal secretion
0.730 0.270 0.000
E61 Deficiency of other nutrient elements
0.729 0.271 0.000
M79.88 Other specified soft tissue disorders (Other)
0.728 0.272 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.726 0.274 0.000
I51.4 Myocarditis, unspecified
0.726 0.274 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.724 0.275 0.000
S10-S19 Injuries to the neck
0.724 0.276 0.000
E27 Other disorders of adrenal gland
0.723 0.277 0.000
S62.6 Fracture of other finger
0.723 0.277 0.000
T78 Adverse effects, not elsewhere classified
0.722 0.278 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.722 0.278 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.721 0.278 0.000
S61 Open wound of wrist and hand
0.721 0.279 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.720 0.279 0.000
H60-H62 Diseases of external ear
0.720 0.280 0.000
I74 Arterial embolism and thrombosis
0.719 0.281 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
E23.6 Other disorders of pituitary gland
0.717 0.282 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.717 0.283 0.000
K62.2 Anal prolapse
0.716 0.284 0.000
M86-M90 Other osteopathies
0.716 0.284 0.000
M19.8 Other specified arthrosis
0.716 0.284 0.000
M19.2 Other secondary arthrosis
0.716 0.284 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.716 0.284 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M15 Polyarthrosis
0.716 0.284 0.000
M51.3 Other specified intervertebral disk degeneration
0.715 0.285 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.715 0.285 0.000
M51.4 Schmorl's nodes
0.715 0.285 0.000
K60.2 Anal fissure, unspecified
0.715 0.285 0.000
M70.6 Trochanteric bursitis
0.714 0.286 0.000
E29 Testicular dysfunction
0.713 0.287 0.000
G61 Inflammatory polyneuropathy
0.713 0.287 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
M53 Other dorsopathies, not elsewhere classified
0.710 0.290 0.000
S67 Crushing injury of wrist and hand
0.709 0.291 0.000
S65 Injury of blood vessels at wrist and hand level
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
L73 Other follicular disorders
0.708 0.292 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.707 0.293 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.707 0.293 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.707 0.293 0.000
I05-I09 Chronic rheumatic heart diseases
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.705 0.295 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.704 0.296 0.000
M67 Other disorders of synovium and tendon
0.704 0.296 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.703 0.297 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.703 0.297 0.000
K62.6 Ulcer of anus and rectum
0.702 0.298 0.000
S64.1 Injury of median nerve at wrist and hand level
0.700 0.300 0.000
M18 Arthrosis of first carpometacarpal joint
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
H61 Other disorders of external ear
0.699 0.301 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.698 0.302 0.000
I49 Other cardiac arrhythmias
0.698 0.302 0.000
I51.6 Cardiovascular disease, unspecified
0.698 0.302 0.000
I51.5 Myocardial degeneration
0.698 0.302 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.698 0.302 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.698 0.302 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.698 0.302 0.000
I51.0 Cardiac septal defect, acquired
0.698 0.302 0.000
K61.3 Ischiorectal abscess
0.698 0.302 0.000
I37 Pulmonary valve disorders
0.697 0.303 0.000
I30 Acute pericarditis
0.697 0.303 0.000
I45 Other conduction disorders
0.695 0.305 0.000
M47 Spondylosis
0.692 0.308 0.000
M75.0 Adhesive capsulitis of shoulder
0.691 0.309 0.000
I23 Certain current complications following acute myocardial infarction
0.691 0.309 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.688 0.312 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.688 0.312 0.000
L73.2 Hidradenitis suppurativa
0.687 0.313 0.000
S99 Other and unspecified injuries of ankle and foot
0.686 0.314 0.000
I78.1 Naevus, nonneoplastic
0.686 0.314 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.683 0.317 0.000
I35.9 Aortic valve disorder, unspecified
0.683 0.317 0.000
M19.1 Posttraumatic arthrosis of other joints
0.682 0.318 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.682 0.318 0.000
M79.9 Soft tissue disorder, unspecified
0.680 0.319 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.680 0.319 0.000
M79.3 Panniculitis, unspecified
0.680 0.319 0.000
M79.2 Neuralgia and neuritis, unspecified
0.680 0.319 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.680 0.320 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.677 0.322 0.000
Q80-Q89 Other congenital malformations
0.677 0.323 0.000
I44.7 Left bundle-branch block, unspecified
0.677 0.323 0.000
E20 Hypoparathyroidism
0.676 0.323 0.000
I25.6 Silent myocardial ischaemia
0.676 0.324 0.000
I25.4 Coronary artery aneurysm
0.676 0.324 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.676 0.324 0.000
E23.2 Diabetes insipidus
0.676 0.324 0.000
M91-M94 Chondropathies
0.675 0.325 0.000
M71 Other bursopathies
0.675 0.325 0.000
I20 Angina pectoris
0.672 0.328 0.000
K61.4 Intrasphincteric abscess
0.672 0.328 0.000
K61.2 Anorectal abscess
0.672 0.328 0.000
K61.1 Rectal abscess
0.672 0.328 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.672 0.328 0.000
E22 Hyperfunction of pituitary gland
0.672 0.328 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.671 0.329 0.000
M48 Other spondylopathies
0.670 0.330 0.000
M54.8 Other dorsalgia
0.668 0.332 0.000
E53.8 Deficiency of other specified B group vitamins
0.668 0.332 0.000
M75.5 Bursitis of shoulder
0.667 0.333 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.666 0.334 0.000
K35-K38 Diseases of appendix
0.665 0.335 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.663 0.336 0.000
I22 Subsequent myocardial infarction
0.663 0.337 0.000
S62.7 Multiple fractures of fingers
0.663 0.337 0.000
S62.4 Multiple fractures of metacarpal bones
0.663 0.337 0.000
S62.1 Fracture of other carpal bone(s)
0.663 0.337 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.663 0.337 0.000
M51.9 Intervertebral disk disorder, unspecified
0.662 0.338 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.660 0.340 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.660 0.340 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.660 0.340 0.000
S63.1 Dislocation finger
0.658 0.341 0.000
S63.7 Sprain and strain of other and unspecified parts of hand
0.658 0.341 0.000
S63.6 Sprain and strain of finger(s)
0.658 0.341 0.000
S63.5 Sprain and strain of wrist
0.658 0.341 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.658 0.341 0.000
S63.2 Multiple dislocations of fingers
0.658 0.341 0.000
S63.0 Dislocation of wrist
0.658 0.341 0.000
K62.7 Radiation proctitis
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.342 0.000
M70.4 Prepatellar bursitis
0.657 0.343 0.000
M80-M85 Disorders of bone density and structure
0.656 0.344 0.000
M51.8 Other specified intervertebral disk disorders
0.655 0.344 0.000
K60.4 Rectal fistula
0.655 0.345 0.000
K83.8 Other specified diseases of biliary tract
0.655 0.345 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.654 0.346 0.000
M20-M25 Other joint disorders
0.654 0.346 0.000
I35.0 Aortic (valve) stenosis
0.654 0.346 0.000
M50.9 Cervical disk disorder, unspecified
0.652 0.348 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.652 0.348 0.000
S62.2 Fracture of first metacarpal bone
0.652 0.348 0.000
E16.2 Hypoglycaemia, unspecified
0.651 0.349 0.000
G70 Myasthenia gravis and other myoneural disorders
0.651 0.349 0.000
I42.8 Other cardiomyopathies
0.650 0.350 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.650 0.350 0.000
I42.6 Alcoholic cardiomyopathy
0.650 0.350 0.000
I42.5 Other restrictive cardiomyopathy
0.650 0.350 0.000
I42.4 Endocardial fibroelastosis
0.650 0.350 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.650 0.350 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.650 0.350 0.000
S64.8 Injury of other nerves at wrist and hand level
0.650 0.350 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.650 0.350 0.000
S20-S29 Injuries to the thorax
0.649 0.351 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.649 0.351 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.648 0.352 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.648 0.352 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.648 0.352 0.000
H61.0 Perichondritis of external ear
0.647 0.353 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.647 0.353 0.000
L91 Hypertrophic disorders of skin
0.647 0.353 0.000
M43 Other deforming dorsopathies
0.646 0.354 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.645 0.354 0.000
M54.1 Radiculopathy
0.645 0.355 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.645 0.355 0.000
E61.1 Iron deficiency
0.645 0.355 0.000
K55.8 Other vascular disorders of intestine
0.644 0.356 0.000
E28 Ovarian dysfunction
0.644 0.356 0.000
I25.5 Ischaemic cardiomyopathy
0.642 0.358 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.642 0.358 0.000
E34 Other endocrine disorders
0.642 0.358 0.000
E32 Diseases of thymus
0.642 0.358 0.000
E31 Polyglandular dysfunction
0.642 0.358 0.000
E30 Disorders of puberty, not elsewhere classified
0.642 0.358 0.000
E26 Hyperaldosteronism
0.642 0.358 0.000
E25 Adrenogenital disorders
0.642 0.358 0.000
E24 Cushing's syndrome
0.642 0.358 0.000
K59.9 Functional intestinal disorder, unspecified
0.641 0.359 0.000
M79.5 Residual foreign body in soft tissue
0.641 0.359 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.640 0.360 0.000
M42 Spinal osteochondrosis
0.639 0.361 0.000
M40 Kyphosis and lordosis
0.639 0.361 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.639 0.361 0.000
I44.2 Atrioventricular block, complete
0.639 0.361 0.000
T92 Sequelae of injuries of upper limb
0.638 0.362 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.638 0.362 0.000
M54.57 Low back pain (Lumbosacral region)
0.638 0.362 0.000
S62.50 Fracture of thumb (closed)
0.635 0.365 0.000
I38 Endocarditis, valve unspecified
0.635 0.365 0.000
M54.50 Low back pain (Multiple sites in spine)
0.634 0.366 0.000
K50-K52 Noninfective enteritis and colitis
0.633 0.367 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.631 0.369 0.000
K59.4 Anal spasm
0.631 0.369 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.631 0.369 0.000
S64.3 Injury of digital nerve of thumb
0.630 0.370 0.000
K85.9 Acute pancreatitis, unspecified
0.629 0.370 0.000
I26 Pulmonary embolism
0.629 0.371 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.629 0.371 0.000
I33.9 Acute endocarditis, unspecified
0.629 0.371 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.628 0.372 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.628 0.372 0.000
S68 Traumatic amputation of wrist and hand
0.627 0.373 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.625 0.375 0.000
M54.4 Lumbago with sciatica
0.625 0.375 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.624 0.376 0.000
G61.0 Guillain-Barre syndrome
0.624 0.376 0.000
G37 Other demyelinating diseases of central nervous system
0.623 0.377 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.623 0.377 0.000
K86.3 Pseudocyst of pancreas
0.622 0.378 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.621 0.379 0.000
M65 Synovitis and tenosynovitis
0.620 0.380 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.619 0.381 0.000
M20 Acquired deformities of fingers and toes
0.619 0.381 0.000
H61.2 Impacted cerumen
0.618 0.382 0.000
M79.6 Pain in limb
0.618 0.382 0.000
M62 Other disorders of muscle
0.617 0.382 0.000
T14 Injury of unspecified body region
0.617 0.383 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.617 0.383 0.000
G90 Disorders of autonomic nervous system
0.616 0.384 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.615 0.385 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.615 0.385 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.615 0.385 0.000
M54.55 Low back pain (Thoracolumbar region)
0.615 0.385 0.000
K60.0 Acute anal fissure
0.614 0.385 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.614 0.385 0.000
M67.8 Other specified disorders of synovium and tendon
0.614 0.386 0.000
L91.8 Other hypertrophic disorders of skin
0.614 0.386 0.000
M54.0 Panniculitis affecting regions of neck and back
0.613 0.387 0.000
E23.7 Disorder of pituitary gland, unspecified
0.613 0.387 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.613 0.387 0.000
E23.1 Drug-induced hypopituitarism
0.613 0.387 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.611 0.389 0.000
K86.2 Cyst of pancreas
0.610 0.389 0.000
M47.8 Other spondylosis
0.610 0.390 0.000
M46 Other inflammatory spondylopathies
0.610 0.390 0.000
I35.8 Other aortic valve disorders
0.610 0.390 0.000
M05-M14 Inflammatory polyarthropathies
0.610 0.390 0.000
M79.10 Myalgia (Multiple sites)
0.610 0.390 0.000
S40 Superficial injury of shoulder and upper arm
0.610 0.390 0.000
S92 Fracture of foot, except ankle
0.609 0.391 0.000
M20.5 Other deformities of toe(s) (acquired)
0.608 0.392 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.608 0.392 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.608 0.392 0.000
E63 Other nutritional deficiencies
0.608 0.392 0.000
E56 Other vitamin deficiencies
0.608 0.392 0.000
E51 Thiamine deficiency
0.608 0.392 0.000
E50 Vitamin A deficiency
0.608 0.392 0.000
E60 Dietary zinc deficiency
0.608 0.392 0.000
E59 Dietary selenium deficiency
0.608 0.392 0.000
E58 Dietary calcium deficiency
0.608 0.392 0.000
E54 Ascorbic acid deficiency
0.608 0.392 0.000
E52 Niacin deficiency [pellagra]
0.608 0.392 0.000
T91 Sequelae of injuries of neck and trunk
0.608 0.392 0.000
I46.1 Sudden cardiac death, so described
0.607 0.392 0.000
M54.6 Pain in thoracic spine
0.605 0.395 0.000
T21 Burn and corrosion of trunk
0.605 0.395 0.000
I49.8 Other specified cardiac arrhythmias
0.605 0.395 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.604 0.395 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.604 0.395 0.000
M70.7 Other bursitis of hip
0.604 0.395 0.000
M70.5 Other bursitis of knee
0.604 0.395 0.000
M70.3 Other bursitis of elbow
0.604 0.395 0.000
M70.2 Olecranon bursitis
0.604 0.395 0.000
M70.1 Bursitis of hand
0.604 0.395 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.604 0.395 0.000
M79.08 Rheumatism, unspecified (Other)
0.604 0.395 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.604 0.395 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.604 0.395 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.604 0.395 0.000
M79.04 Rheumatism, unspecified (Hand)
0.604 0.395 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.604 0.395 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.604 0.395 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.604 0.395 0.000
I35.1 Aortic (valve) insufficiency
0.605 0.395 0.000
I70 Atherosclerosis
0.601 0.399 0.000
S62.31 Fracture of other metacarpal bone (open)
0.601 0.399 0.000
S98 Traumatic amputation of ankle and foot
0.601 0.399 0.000
S97 Crushing injury of ankle and foot
0.601 0.399 0.000
S95 Injury of blood vessels at ankle and foot level
0.601 0.399 0.000
S94 Injury of nerves at ankle and foot level
0.601 0.399 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.601 0.399 0.000
M54.9 Dorsalgia, unspecified
0.601 0.399 0.000
L60 Nail disorders
0.601 0.399 0.000
K82 Other diseases of gallbladder
0.600 0.400 0.000
T75 Effects of other external causes
0.598 0.401 0.000
T74 Maltreatment syndromes
0.598 0.401 0.000
T73 Effects of other deprivation
0.598 0.401 0.000
T70 Effects of air pressure and water pressure
0.598 0.401 0.000
T69 Other effects of reduced temperature
0.598 0.401 0.000
T67 Effects of heat and light
0.598 0.401 0.000
T71 Asphyxiation
0.598 0.401 0.000
T68 Hypothermia
0.598 0.401 0.000
T66 Unspecified effects of radiation
0.598 0.401 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.598 0.401 0.000
M66 Spontaneous rupture of synovium and tendon
0.598 0.401 0.000
M49 Spondylopathies in diseases classified elsewhere
0.598 0.402 0.000
M99 Biomechanical lesions, not elsewhere classified
0.597 0.403 0.000
Q60-Q64 Congenital malformations of the urinary system
0.597 0.403 0.000
O26.9 Pregnancy-related condition, unspecified
0.597 0.403 0.000
K83.1 Obstruction of bile duct
0.596 0.404 0.000
M77.4 Metatarsalgia
0.596 0.404 0.000
I25.3 Aneurysm of heart
0.595 0.405 0.000
T90 Sequelae of injuries of head
0.595 0.405 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.594 0.406 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.593 0.407 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.593 0.407 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.593 0.407 0.000
I20.0 Unstable angina
0.592 0.408 0.000
G91 Hydrocephalus
0.590 0.410 0.000
M47.86 Other spondylosis (Lumbar region)
0.590 0.410 0.000
M79.19 Myalgia (Site unspecified)
0.589 0.411 0.000
L82 Seborrhoeic keratosis
0.588 0.412 0.000
S90 Superficial injury of ankle and foot
0.588 0.412 0.000
S69.9 Unspecified injury of wrist and hand
0.587 0.413 0.000
S62.61 Fracture of other finger (open)
0.587 0.413 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.587 0.413 0.000
Q82 Other congenital malformations of skin
0.586 0.413 0.000
G61.8 Other inflammatory polyneuropathies
0.585 0.415 0.000
M50.8 Other cervical disk disorders
0.585 0.415 0.000
I47 Paroxysmal tachycardia
0.585 0.415 0.000
M20.4 Other hammer toe(s) (acquired)
0.585 0.415 0.000
I08 Multiple valve diseases
0.584 0.416 0.000
K55.9 Vascular disorder of intestine, unspecified
0.584 0.416 0.000
I73.8 Other specified peripheral vascular diseases
0.584 0.416 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.584 0.416 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.584 0.416 0.000
G96 Other disorders of central nervous system
0.584 0.416 0.000
T98 Sequelae of other and unspecified effects of external causes
0.584 0.416 0.000
T95 Sequelae of burns, corrosions and frostbite
0.584 0.416 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.584 0.416 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.584 0.416 0.000
M72 Fibroblastic disorders
0.583 0.417 0.000
E55 Vitamin D deficiency
0.582 0.417 0.000
E15 Nondiabetic hypoglycaemic coma
0.582 0.418 0.000
M41.8 Other forms of scoliosis
0.582 0.418 0.000
M41.5 Other secondary scoliosis
0.582 0.418 0.000
M41.4 Neuromuscular scoliosis
0.582 0.418 0.000
M41.3 Thoracogenic scoliosis
0.582 0.418 0.000
M41.2 Other idiopathic scoliosis
0.582 0.418 0.000
M41.1 Juvenile idiopathic scoliosis
0.582 0.418 0.000
M41.0 Infantile idiopathic scoliosis
0.582 0.418 0.000
E29.1 Testicular hypofunction
0.582 0.418 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.581 0.419 0.000
L89 Decubitus ulcer
0.581 0.419 0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level
0.581 0.419 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.581 0.419 0.000
K55.0 Acute vascular disorders of intestine
0.581 0.419 0.000
G71 Primary disorders of muscles
0.580 0.420 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.579 0.421 0.000
M54.3 Sciatica
0.578 0.422 0.000
M21 Other acquired deformities of limbs
0.578 0.422 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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