TreeWAS – Variant ID: rs11724635

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.416	0.584	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.415	0.585	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.414	0.586	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.413	0.587	0.000
T43.2 Other and unspecified antidepressants	0.407	0.593	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.386	0.614	0.000
T36 Poisoning by systemic antibiotics	0.375	0.625	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.346	0.654	0.000
T43.9 Psychotropic drug, unspecified	0.341	0.659	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.339	0.661	0.000
T42.3 Barbiturates	0.337	0.663	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.337	0.663	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.335	0.665	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.332	0.668	0.000
T42.1 Iminostilbenes	0.329	0.671	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.329	0.671	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.326	0.674	0.000
T36.0 Penicillins	0.325	0.674	0.000
T36.3 Macrolides	0.305	0.695	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.298	0.702	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.297	0.703	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.297	0.703	0.000
T42.2 Succinimides and oxazolidinediones	0.297	0.703	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.296	0.704	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.292	0.708	0.000
T42.0 Hydantoin derivatives	0.290	0.710	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.290	0.710	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.288	0.712	0.000
T40.2 Other opioids	0.287	0.713	0.000
T36.4 Tetracyclines	0.287	0.713	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.278	0.722	0.000
T39.1 4-Aminophenol derivatives	0.274	0.726	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.273	0.727	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.271	0.729	0.000
T36.8 Other systemic antibiotics	0.269	0.731	0.000
T36.9 Systemic antibiotic, unspecified	0.269	0.731	0.000
T36.7 Antifungal antibiotics, systemically used	0.269	0.731	0.000
T36.6 Rifamycins	0.269	0.731	0.000
T36.5 Aminoglycosides	0.269	0.731	0.000
T36.2 Chloramphenicol group	0.269	0.731	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.269	0.731	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.267	0.733	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.266	0.734	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.261	0.738	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.256	0.743	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.256	0.744	0.000
T45.4 Iron and its compounds	0.256	0.744	0.000
T40.6 Other and unspecified narcotics	0.253	0.747	0.000
T43.6 Psychostimulants with abuse potential	0.250	0.750	0.000
T40.3 Methadone	0.248	0.751	0.000
T45.2 Vitamins, not elsewhere classified	0.245	0.755	0.000
T45.0 Antiallergic and antiemetic drugs	0.245	0.755	0.000
T45.5 Anticoagulants	0.245	0.755	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.244	0.756	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.242	0.758	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.242	0.758	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.242	0.758	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.242	0.758	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.242	0.758	0.000
T44.0 Anticholinesterase agents	0.242	0.758	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.238	0.762	0.000
T40.8 Lysergide [LSD]	0.238	0.762	0.000
T40.7 Cannabis (derivatives)	0.238	0.762	0.000
T40.0 Opium	0.238	0.762	0.000
T40.1 Heroin	0.236	0.763	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.236	0.764	0.000
T45.8 Other primarily systemic and haematological agents	0.236	0.764	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.236	0.764	0.000
T45.6 Fibrinolysis-affecting drugs	0.236	0.764	0.000
T45.3 Enzymes, not elsewhere classified	0.236	0.764	0.000
T39.4 Antirheumatics, not elsewhere classified	0.234	0.766	0.000
T39.2 Pyrazolone derivatives	0.234	0.766	0.000
T40.5 Cocaine	0.233	0.767	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.232	0.768	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.231	0.769	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.226	0.774	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.224	0.776	0.000
T46.1 Calcium-channel blockers	0.216	0.784	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.214	0.786	0.000
T41.5 Therapeutic gases	0.212	0.788	0.000
T41.4 Anaesthetic, unspecified	0.212	0.788	0.000
T41.3 Local anaesthetics	0.212	0.788	0.000
T41.2 Other and unspecified general anaesthetics	0.212	0.788	0.000
T41.1 Intravenous anaesthetics	0.212	0.788	0.000
T41.0 Inhaled anaesthetics	0.212	0.788	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.209	0.790	0.000
T37.5 Antiviral drugs	0.209	0.790	0.000
T37.4 Anthelminthics	0.209	0.790	0.000
T37.3 Other antiprotozoal drugs	0.209	0.790	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.209	0.790	0.000
T37.1 Antimycobacterial drugs	0.209	0.790	0.000
T37.0 Sulphonamides	0.209	0.790	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.208	0.792	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.208	0.792	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.208	0.792	0.000
T46.7 Peripheral vasodilators	0.208	0.792	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.207	0.792	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.205	0.794	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.205	0.795	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.200	0.800	0.000
T38.0 Glucocorticoids and synthetic analogues	0.195	0.804	0.000
T47.0 Histamine H(2)-receptor antagonists	0.195	0.804	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.194	0.806	0.000
T48.4 Expectorants	0.194	0.806	0.000
T48.3 Antitussives	0.194	0.806	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.194	0.806	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.194	0.806	0.000
T48.0 Oxytocic drugs	0.194	0.806	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.191	0.809	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.191	0.809	0.000
T47.7 Emetics	0.191	0.809	0.000
T47.5 Digestants	0.191	0.809	0.000
T47.3 Saline and osmotic laxatives	0.191	0.809	0.000
T39.0 Salicylates	0.191	0.809	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.190	0.809	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.188	0.812	0.000
T49.9 Topical agent, unspecified	0.188	0.812	0.000
T49.8 Other topical agents	0.188	0.812	0.000
T49.7 Dental drugs, topically applied	0.188	0.812	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.188	0.812	0.000
T49.5 Ophthalmological drugs and preparations	0.188	0.812	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.188	0.812	0.000
T49.3 Emollients, demulcents and protectants	0.188	0.812	0.000
T49.2 Local astringents and local detergents	0.188	0.812	0.000
T49.1 Antipruritics	0.188	0.812	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.186	0.814	0.000
T40.4 Other synthetic narcotics	0.185	0.815	0.000
T47.6 Antidiarrhoeal drugs	0.183	0.817	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.181	0.819	0.000
T47.4 Other laxatives	0.181	0.819	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.180	0.820	0.000
T48.5 Anti-common-cold drugs	0.176	0.823	0.000
T38.9 Other and unspecified hormone antagonists	0.175	0.825	0.000
T38.7 Androgens and anabolic congeners	0.175	0.825	0.000
T38.5 Other oestrogens and progestogens	0.175	0.825	0.000
T38.4 Oral contraceptives	0.175	0.825	0.000
T38.2 Antithyroid drugs	0.175	0.825	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.167	0.833	0.000
T50.7 Analeptics and opioid receptor antagonists	0.167	0.833	0.000
T50.5 Appetite depressants	0.167	0.833	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.167	0.833	0.000
T50.1 Loop [high-ceiling] diuretics	0.167	0.833	0.000
T50.0 Mineralocorticoids and their antagonists	0.167	0.833	0.000
T50.8 Diagnostic agents	0.166	0.834	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.162	0.837	0.000
T42.4 Benzodiazepines	0.160	0.840	0.000
T50.4 Drugs affecting uric acid metabolism	0.159	0.841	0.000
T47.2 Stimulant laxatives	0.155	0.845	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.153	0.846	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.148	0.851	0.000
T38.1 Thyroid hormones and substitutes	0.131	0.868	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.125	0.875	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.886	0.114
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.890	0.110
T78.2 Anaphylactic shock, unspecified	0.000	0.892	0.108
T78.4 Allergy, unspecified	0.000	0.894	0.106
T78.3 Angioneurotic oedema	0.000	0.900	0.100
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.903	0.097
T78.8 Other adverse effects, not elsewhere classified	0.000	0.909	0.091
T78.9 Adverse effect, unspecified	0.000	0.923	0.077
T50.9 Other and unspecified drugs, medicaments and biological substances	0.067	0.932	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.937	0.063
T66-T78 Other and unspecified effects of external causes	0.000	0.952	0.048
T68 Hypothermia	0.000	0.961	0.039
T71 Asphyxiation	0.000	0.962	0.038
T66 Unspecified effects of radiation	0.000	0.965	0.035
T74 Maltreatment syndromes	0.000	0.966	0.034
T73 Effects of other deprivation	0.000	0.966	0.034
T69 Other effects of reduced temperature	0.000	0.966	0.034
T67 Effects of heat and light	0.000	0.966	0.034
T75 Effects of other external causes	0.000	0.972	0.028
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.972	0.028
T70 Effects of air pressure and water pressure	0.000	0.972	0.027
T67.9 Effects of heat and light, unspecified	0.000	0.975	0.025
T67.8 Other effects of heat and light	0.000	0.975	0.025
T67.7 Heat oedema	0.000	0.975	0.025
T67.6 Heat fatigue, transient	0.000	0.975	0.025
T67.5 Heat exhaustion, unspecified	0.000	0.975	0.025
T67.4 Heat exhaustion due to salt depletion	0.000	0.975	0.025
T67.3 Heat exhaustion, anhydrotic	0.000	0.975	0.025
T67.2 Heat cramp	0.000	0.975	0.025
T67.1 Heat syncope	0.000	0.975	0.025
T67.0 Heatstroke and sunstroke	0.000	0.975	0.025
T69.9 Effect of reduced temperature, unspecified	0.000	0.975	0.025
T69.8 Other specified effects of reduced temperature	0.000	0.975	0.025
T69.1 Chilblains	0.000	0.975	0.025
T69.0 Immersion hand and foot	0.000	0.975	0.025
T73.9 Effect of deprivation, unspecified	0.000	0.975	0.025
T73.8 Other effects of deprivation	0.000	0.975	0.025
T73.3 Exhaustion due to excessive exertion	0.000	0.975	0.025
T73.2 Exhaustion due to exposure	0.000	0.975	0.025
T73.1 Effects of thirst	0.000	0.975	0.025
T73.0 Effects of hunger	0.000	0.975	0.025
T74.9 Maltreatment syndrome, unspecified	0.000	0.975	0.025
T74.8 Other maltreatment syndromes	0.000	0.975	0.025
T74.3 Psychological abuse	0.000	0.975	0.025
T74.2 Sexual abuse	0.000	0.975	0.025
T74.1 Physical abuse	0.000	0.975	0.025
T74.0 Neglect or abandonment	0.000	0.975	0.025
T75.8 Other specified effects of external causes	0.000	0.979	0.020
T75.3 Motion sickness	0.000	0.979	0.020
T75.2 Effects of vibration	0.000	0.979	0.020
T75.0 Effects of lightning	0.000	0.979	0.020
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.980	0.020
T70.8 Other effects of air pressure and water pressure	0.000	0.980	0.020
T70.4 Effects of high-pressure fluids	0.000	0.980	0.020
T70.2 Other and unspecified effects of high altitude	0.000	0.980	0.020
T70.1 Sinus barotrauma	0.000	0.980	0.020
T70.0 Otitic barotrauma	0.000	0.980	0.020
T75.1 Drowning and nonfatal submersion	0.000	0.981	0.018
Z99.8 Dependence on other enabling machines and devices	0.000	0.982	0.018
T75.4 Effects of electric current	0.000	0.983	0.017
I24 Other acute ischaemic heart diseases	0.000	0.986	0.014
T70.3 Caisson disease [decompression sickness]	0.001	0.987	0.013
I24.8 Other forms of acute ischaemic heart disease	0.000	0.987	0.013
K82.8 Other specified diseases of gallbladder	0.011	0.989	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.991	0.009
R00.1 Bradycardia, unspecified	0.000	0.991	0.009
E10.1 With ketoacidosis	0.008	0.992	0.000
K82.9 Disease of gallbladder, unspecified	0.008	0.992	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.993	0.007
I24.1 Dressler's syndrome	0.000	0.993	0.007
K82 Other diseases of gallbladder	0.007	0.993	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.993	0.007
M54.39 Sciatica (Site unspecified)	0.000	0.993	0.007
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.993	0.006
D75.2 Essential thrombocytosis	0.000	0.994	0.006
D75.1 Secondary polycythaemia	0.000	0.994	0.006
R09.0 Asphyxia	0.000	0.994	0.006
N94.4 Primary dysmenorrhoea	0.000	0.994	0.006
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.994	0.006
H54.0 Blindness, both eyes	0.000	0.994	0.006
N94.6 Dysmenorrhoea, unspecified	0.000	0.994	0.006
N94.1 Dyspareunia	0.000	0.994	0.006
K82.0 Obstruction of gallbladder	0.005	0.995	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.000	0.995	0.005
H54.9 Unspecified visual impairment (binocular)	0.000	0.995	0.005
K82.1 Hydrops of gallbladder	0.005	0.995	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.005	0.995	0.000
H54 Blindness and low vision	0.000	0.995	0.005
N94.3 Premenstrual tension syndrome	0.000	0.995	0.005
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.995	0.005
M85.8 Other specified disorders of bone density and structure	0.005	0.995	0.000
D75.0 Familial erythrocytosis	0.000	0.995	0.005
R00 Abnormalities of heart beat	0.000	0.995	0.005
M85.88 Other specified disorders of bone density and structure (Other)	0.005	0.995	0.000
C16.0 Cardia	0.000	0.995	0.005
C16.3 Pyloric antrum	0.000	0.995	0.005
K82.3 Fistula of gallbladder	0.004	0.995	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.004	0.996	0.000
N94.0 Mittelschmerz	0.000	0.996	0.004
K82.2 Perforation of gallbladder	0.004	0.996	0.000
H54.5 Low vision, one eye	0.000	0.996	0.004
H54.7 Unspecified visual loss	0.000	0.996	0.004
C16 Malignant neoplasm of stomach	0.000	0.996	0.004
H54.6 Unqualified visual loss, one eye	0.000	0.996	0.004
H54.2 Low vision, both eyes	0.000	0.996	0.004
H54.1 Blindness, one eye, low vision, other eye	0.000	0.996	0.004
M54.3 Sciatica	0.000	0.996	0.004
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.004	0.996	0.000
H54.4 Blindness, one eye	0.000	0.996	0.004
R00.0 Tachycardia, unspecified	0.000	0.996	0.004
S91.3 Open wound of other parts of foot	0.000	0.996	0.004
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.004	0.996	0.000
N83.2 Other and unspecified ovarian cysts	0.000	0.996	0.004
M85.83 Other specified disorders of bone density and structure (Forearm)	0.004	0.996	0.000
N94.5 Secondary dysmenorrhoea	0.000	0.996	0.004
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.004	0.996	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.004	0.996	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.004	0.996	0.000
N94.2 Vaginismus	0.000	0.996	0.004
O36.5 Maternal care for poor foetal growth	0.000	0.996	0.004
C16.5 Lesser curvature of stomach, unspecified	0.000	0.996	0.004
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.996	0.004
C16.4 Pylorus	0.000	0.996	0.004
H54.3 Unqualified visual loss, both eyes	0.000	0.996	0.003
C16.9 Stomach, unspecified	0.000	0.996	0.004
S62.40 Multiple fractures of metacarpal bones (closed)	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.000	0.997	0.003
M54.37 Sciatica (Lumbosacral region)	0.000	0.997	0.003
C16.2 Body of stomach	0.000	0.997	0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.997	0.003
C16.1 Fundus of stomach	0.000	0.997	0.003
M54.35 Sciatica (Thoracolumbar region)	0.000	0.997	0.003
M54.34 Sciatica-Thoracic	0.000	0.997	0.003
M54.33 Sciatica-Cervicothoracic	0.000	0.997	0.003
M54.32 Sciatica-Cervical	0.000	0.997	0.003
M54.31 Sciatica-Occipit-atl-axl	0.000	0.997	0.003
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.000	0.997	0.003
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
Z00.5 Examination of potential donor of organ and tissue	0.003	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.997	0.003
M54.30 Sciatica (Multiple sites in spine)	0.000	0.997	0.003
C71.2 Temporal lobe	0.003	0.997	0.000
Z83.3 Family history of diabetes mellitus	0.003	0.997	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.997	0.003
G47.9 Sleep disorder, unspecified	0.000	0.997	0.003
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.997	0.003
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.997	0.003
C16.8 Overlapping lesion of stomach	0.000	0.997	0.003
A02.0 Salmonella gastro-enteritis	0.003	0.997	0.000
G44.2 Tension-type headache	0.002	0.997	0.000
G47.4 Narcolepsy and cataplexy	0.000	0.997	0.002
G47.3 Sleep apnoea	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.000	0.998	0.002
G47 Sleep disorders	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
Z99.4 Dependence on artificial heart	0.000	0.998	0.002
C88.0 Waldenstrom's macroglobulinaemia	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.998	0.002
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.998	0.002
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.002	0.998	0.000
Z99.0 Dependence on aspirator	0.000	0.998	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.998	0.002
S05.8 Other injuries of eye and orbit	0.000	0.998	0.002
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
G44.8 Other specified headache syndromes	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
S05 Injury of eye and orbit	0.000	0.998	0.002
C44.0 Skin of lip	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
M87 Osteonecrosis	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.998	0.002
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.998	0.002
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.998	0.002
J99.8 Respiratory disorders in other diseases classified elsewhere	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
Y84.1 Kidney dialysis	0.000	0.998	0.002
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.002	0.998	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.998	0.002
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.998	0.002
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.002
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
Z37.2 Twins, both liveborn	0.000	0.998	0.002
M89 Other disorders of bone	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M87.8 Other osteonecrosis	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
Z50.2 Alcohol rehabilitation	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.998	0.002
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
S05.7 Avulsion of eye	0.000	0.998	0.002
M85 Other disorders of bone density and structure	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
M87.3 Other secondary osteonecrosis	0.002	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
U88 Agent resistant to multiple antibiotics	0.000	0.998	0.002
M86-M90 Other osteopathies	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M86.8 Other osteomyelitis	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
W02.9 Unspecified place	0.000	0.998	0.002
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.998	0.002
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
C08.9 Major salivary gland, unspecified	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.002	0.998	0.000
C85.1 B-cell lymphoma, unspecified	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.998	0.001
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.998	0.000
A02.1 Salmonella septicaemia	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.998	0.001
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.998	0.002
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.000	0.998	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.001	0.998	0.000
M89.2 Other disorders of bone development and growth	0.001	0.998	0.000
M89.1 Epiphyseal arrest	0.001	0.998	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.998	0.002
A02 Other Salmonella infections	0.002	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.001
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.001	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.998	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.001	0.998	0.000
M86.3 Chronic multifocal osteomyelitis	0.001	0.998	0.000
M86.2 Subacute osteomyelitis	0.001	0.998	0.000
M86.1 Other acute osteomyelitis	0.001	0.998	0.000
M86.0 Acute haematogenous osteomyelitis	0.001	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.998	0.001
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.001
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.001	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.001	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.001	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.001	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.001	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.001	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.001	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.001	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.001	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.998	0.000
M90.19 Periostitis in other infectious diseases classified elsewhere (Site unspecified)	0.001	0.998	0.000
M90.18 Periostitis in other infectious diseases classified elsewhere (Other)	0.001	0.998	0.000
M90.17 Periostitis in other infectious diseases classified elsewhere (Ankle and foot)	0.001	0.998	0.000
M90.16 Periostitis in other infectious diseases classified elsewhere (Lower leg)	0.001	0.998	0.000
M90.15 Periostitis in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.001	0.998	0.000
M90.14 Periostitis in other infectious diseases classified elsewhere (Hand)	0.001	0.998	0.000
M90.13 Periostitis in other infectious diseases classified elsewhere (Forearm)	0.001	0.998	0.000
M90.12 Periostitis in other infectious diseases classified elsewhere (Upper arm)	0.001	0.998	0.000
M90.11 Periostitis in other infectious diseases classified elsewhere (Shoulder region)	0.001	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.998	0.000
D12.7 Rectosigmoid junction	0.000	0.998	0.002
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.998	0.002
M85.5 Aneurysmal bone cyst	0.001	0.998	0.000
M85.3 Osteitis condensans	0.001	0.998	0.000
M85.1 Skeletal fluorosis	0.001	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.001	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.001	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.998	0.000
M90.0 Tuberculosis of bone	0.001	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.001	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.998	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.998	0.001
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations