TreeWAS – Variant ID: rs117292830

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.001	0.999
# Top node	0.998	0.002	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.985	0.015	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.984	0.016	0.000
E03 Other hypothyroidism	0.000	0.020	0.980
K51.9 Ulcerative colitis, unspecified	0.971	0.029	0.000
K51 Ulcerative colitis	0.970	0.030	0.000
E00-E07 Disorders of thyroid gland	0.000	0.033	0.966
Chapter XII Diseases of the skin and subcutaneous tissue	0.963	0.037	0.000
K50-K52 Noninfective enteritis and colitis	0.962	0.038	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.957	0.043	0.000
Chapter VII Diseases of the eye and adnexa	0.956	0.044	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.049	0.950
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.950	0.050	0.000
Chapter XI Diseases of the digestive system	0.949	0.051	0.000
H20 Iridocyclitis	0.946	0.054	0.000
Chapter I Certain infectious and parasitic diseases	0.946	0.054	0.000
H20.9 Iridocyclitis, unspecified	0.943	0.057	0.000
Chapter V Mental and behavioural disorders	0.942	0.058	0.000
M07 Psoriatic and enteropathic arthropathies	0.939	0.061	0.000
M06.0 Seronegative rheumatoid arthritis	0.933	0.067	0.000
E10-E14 Diabetes mellitus	0.000	0.074	0.926
O32 Maternal care for known or suspected malpresentation of foetus	0.926	0.074	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.921	0.079	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.079	0.920
O00-O08 Pregnancy with abortive outcome	0.913	0.087	0.000
E10.9 Without complications	0.000	0.088	0.912
Chapter XXII Codes for special purposes	0.897	0.103	0.000
M07.3 Other psoriatic arthropathies	0.895	0.105	0.000
F30-F39 Mood [affective] disorders	0.892	0.108	0.000
B95-B98 Bacterial, viral and other infectious agents	0.888	0.112	0.000
Chapter II Neoplasms	0.881	0.119	0.000
M05 Seropositive rheumatoid arthritis	0.875	0.125	0.000
M15-M19 Arthrosis	0.874	0.126	0.000
F31 Bipolar affective disorder	0.874	0.126	0.000
K50 Crohn's disease [regional enteritis]	0.872	0.128	0.000
D10-D36 Benign neoplasms	0.871	0.129	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.869	0.131	0.000
M19 Other arthrosis	0.866	0.134	0.000
O32.1 Maternal care for breech presentation	0.866	0.134	0.000
L40-L45 Papulosquamous disorders	0.866	0.134	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.866	0.134	0.000
K51.2 Ulcerative (chronic) proctitis	0.858	0.142	0.000
M19.9 Arthrosis, unspecified	0.858	0.142	0.000
H55-H59 Other disorders of eye and adnexa	0.856	0.144	0.000
O42 Premature rupture of membranes	0.852	0.148	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.851	0.149	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.849	0.151	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.845	0.155	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.844	0.156	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.843	0.157	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.840	0.160	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.838	0.162	0.000
E07 Other disorders of thyroid	0.000	0.164	0.836
M47 Spondylosis	0.836	0.164	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.170	0.829
M19.90 Arthrosis, unspecified (Multiple sites)	0.827	0.173	0.000
D17 Benign lipomatous neoplasm	0.825	0.175	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.820	0.180	0.000
O03 Spontaneous abortion	0.819	0.180	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.815	0.185	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.805	0.195	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.802	0.198	0.000
D22 Melanocytic naevi	0.802	0.198	0.000
L03 Cellulitis	0.799	0.201	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.798	0.202	0.000
K35-K38 Diseases of appendix	0.798	0.202	0.000
M00-M03 Infectious arthropathies	0.796	0.204	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.796	0.204	0.000
O43 Placental disorders	0.792	0.207	0.000
L40 Psoriasis	0.792	0.208	0.000
K50.9 Crohn's disease, unspecified	0.791	0.209	0.000
O30 Multiple gestation	0.790	0.210	0.000
M06.4 Inflammatory polyarthropathy	0.787	0.213	0.000
M86-M90 Other osteopathies	0.787	0.213	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.786	0.214	0.000
Q60-Q64 Congenital malformations of the urinary system	0.785	0.215	0.000
E10.3 With ophthalmic complications	0.000	0.216	0.784
M06.3 Rheumatoid nodule	0.782	0.218	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.781	0.219	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.779	0.221	0.000
K50.1 Crohn's disease of large intestine	0.776	0.224	0.000
O04 Medical abortion	0.773	0.227	0.000
L40.5 Arthropathic psoriasis	0.770	0.230	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.767	0.233	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.767	0.233	0.000
F80-F89 Disorders of psychological development	0.766	0.234	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.765	0.235	0.000
B99-B99 Other infectious diseases	0.761	0.239	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.758	0.242	0.000
F10.2 Dependence syndrome	0.758	0.242	0.000
O32.0 Maternal care for unstable lie	0.757	0.243	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.756	0.244	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.754	0.246	0.000
H57 Other disorders of eye and adnexa	0.753	0.247	0.000
L20-L30 Dermatitis and eczema	0.753	0.247	0.000
O03.4 Incomplete, without complication	0.750	0.250	0.000
K51.5 Mucosal proctocolitis	0.750	0.250	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.749	0.251	0.000
M65-M68 Disorders of synovium and tendon	0.748	0.252	0.000
F10.0 Acute intoxication	0.747	0.253	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.744	0.256	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.257	0.743
E07.9 Disorder of thyroid, unspecified	0.000	0.257	0.743
O32.8 Maternal care for other malpresentation of foetus	0.742	0.258	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.740	0.260	0.000
E20-E35 Disorders of other endocrine glands	0.001	0.261	0.738
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.737	0.263	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.737	0.263	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.737	0.263	0.000
D11 Benign neoplasm of major salivary glands	0.732	0.268	0.000
F31.9 Bipolar affective disorder, unspecified	0.731	0.269	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.730	0.270	0.000
F99-F99 Unspecified mental disorder	0.730	0.270	0.000
H20.0 Acute and subacute iridocyclitis	0.729	0.271	0.000
H18 Other disorders of cornea	0.728	0.272	0.000
B35-B49 Mycoses	0.726	0.274	0.000
Q18 Other congenital malformations of face and neck	0.725	0.275	0.000
K37 Unspecified appendicitis	0.724	0.276	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.721	0.279	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.719	0.281	0.000
F60-F69 Disorders of adult personality and behaviour	0.717	0.283	0.000
L50-L54 Urticaria and erythema	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.717	0.283	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M49 Spondylopathies in diseases classified elsewhere	0.717	0.283	0.000
M47.9 Spondylosis, unspecified	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.716	0.284	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.715	0.285	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.714	0.286	0.000
O85-O92 Complications predominantly related to the puerperium	0.712	0.288	0.000
E65-E68 Obesity and other hyperalimentation	0.001	0.288	0.711
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.288	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.711	0.288	0.000
K51.8 Other ulcerative colitis	0.710	0.290	0.000
O02 Other abnormal products of conception	0.710	0.290	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.709	0.291	0.000
O40 Polyhydramnios	0.708	0.292	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.708	0.292	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.707	0.293	0.000
H53-H54 Visual disturbances and blindness	0.706	0.293	0.000
D34 Benign neoplasm of thyroid gland	0.704	0.296	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.703	0.297	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.703	0.297	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.703	0.297	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.703	0.297	0.000
D26 Other benign neoplasms of uterus	0.703	0.297	0.000
E03.8 Other specified hypothyroidism	0.000	0.297	0.702
E03.5 Myxoedema coma	0.000	0.297	0.702
E03.4 Atrophy of thyroid (acquired)	0.000	0.297	0.702
E03.3 Postinfectious hypothyroidism	0.000	0.297	0.702
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.297	0.702
E03.1 Congenital hypothyroidism without goitre	0.000	0.297	0.702
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.297	0.702
M46 Other inflammatory spondylopathies	0.702	0.297	0.000
H40-H42 Glaucoma	0.702	0.298	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.702	0.298	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.700	0.300	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.301	0.699
M19.0 Primary arthrosis of other joints	0.698	0.302	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.695	0.305	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.695	0.305	0.000
E06 Thyroiditis	0.000	0.307	0.693
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.307	0.693
E00 Congenital iodine-deficiency syndrome	0.000	0.307	0.693
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.307	0.693
H55 Nystagmus and other irregular eye movements	0.692	0.308	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.692	0.308	0.000
M91-M94 Chondropathies	0.691	0.309	0.000
L10-L14 Bullous disorders	0.690	0.310	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.690	0.310	0.000
E50-E64 Other nutritional deficiencies	0.001	0.312	0.687
C92 Myeloid leukaemia	0.688	0.312	0.000
M11 Other crystal arthropathies	0.687	0.313	0.000
O80-O84 Delivery	0.687	0.313	0.000
O45 Premature separation of placenta [abruptio placentae]	0.686	0.314	0.000
O44 Placenta praevia	0.686	0.314	0.000
O41 Other disorders of amniotic fluid and membranes	0.686	0.314	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.686	0.314	0.000
O33 Maternal care for known or suspected disproportion	0.686	0.314	0.000
O31 Complications specific to multiple gestation	0.686	0.314	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.685	0.315	0.000
E10.4 With neurological complications	0.000	0.315	0.685
L03.9 Cellulitis, unspecified	0.684	0.316	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.682	0.317	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.682	0.318	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.682	0.318	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.319	0.681
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.681	0.319	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.681	0.319	0.000
H17 Corneal scars and opacities	0.681	0.319	0.000
H15 Disorders of sclera	0.681	0.319	0.000
Q61 Cystic kidney disease	0.681	0.319	0.000
F30 Manic episode	0.681	0.319	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.680	0.319	0.000
H20.8 Other iridocyclitis	0.679	0.321	0.000
H20.2 Lens-induced iridocyclitis	0.679	0.321	0.000
H20.1 Chronic iridocyclitis	0.679	0.321	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.678	0.321	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.678	0.321	0.000
B65-B83 Helminthiases	0.678	0.321	0.000
B50-B64 Protozoal diseases	0.678	0.321	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.678	0.321	0.000
A75-A79 Rickettsioses	0.678	0.321	0.000
A70-A74 Other diseases caused by chlamydiae	0.678	0.321	0.000
A65-A69 Other spirochaetal diseases	0.678	0.321	0.000
A20-A28 Certain zoonotic bacterial diseases	0.678	0.321	0.000
A15-A19 Tuberculosis	0.678	0.321	0.000
C81 Hodgkin's disease	0.677	0.323	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.675	0.325	0.000
F70-F79 Mental retardation	0.675	0.325	0.000
O47 False labour	0.675	0.325	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.674	0.326	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.673	0.327	0.000
M07.6 Other enteropathic arthropathies	0.673	0.327	0.000
M07.5 Arthropathy in ulcerative colitis	0.673	0.327	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.673	0.327	0.000
M07.2 Psoriatic spondylitis	0.673	0.327	0.000
M07.1 Arthritis mutilans	0.673	0.327	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.673	0.327	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.673	0.327	0.000
E13 Other specified diabetes mellitus	0.000	0.329	0.671
O30.0 Twin pregnancy	0.671	0.329	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.669	0.331	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.669	0.331	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.669	0.331	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.669	0.331	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.669	0.331	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.669	0.331	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.669	0.331	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.669	0.331	0.000
O43.1 Malformation of placenta	0.669	0.331	0.000
D30 Benign neoplasm of urinary organs	0.668	0.331	0.000
M10 Gout	0.667	0.333	0.000
O20 Haemorrhage in early pregnancy	0.667	0.333	0.000
Q80-Q89 Other congenital malformations	0.667	0.333	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.666	0.334	0.000
U88 Agent resistant to multiple antibiotics	0.666	0.334	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.666	0.334	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.665	0.335	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.336	0.664
O32.9 Maternal care for malpresentation of foetus, unspecified	0.664	0.336	0.000
O32.6 Maternal care for compound presentation	0.664	0.336	0.000
O32.4 Maternal care for high head at term	0.664	0.336	0.000
O32.3 Maternal care for face, brow and chin presentation	0.664	0.336	0.000
O32.2 Maternal care for transverse and oblique lie	0.664	0.336	0.000
O42.9 Premature rupture of membranes, unspecified	0.664	0.336	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.663	0.337	0.000
L57.0 Actinic keratosis	0.663	0.337	0.000
M40-M43 Deforming dorsopathies	0.662	0.338	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.662	0.338	0.000
B15-B19 Viral hepatitis	0.661	0.339	0.000
E10.8 With unspecified complications	0.000	0.340	0.660
E10.7 With multiple complications	0.000	0.340	0.660
E10.6 With other specified complications	0.000	0.340	0.660
E10.5 With peripheral circulatory complications	0.000	0.340	0.660
E10.2 With renal complications	0.000	0.340	0.660
E10.1 With ketoacidosis	0.000	0.340	0.660
E10.0 With coma	0.000	0.340	0.660
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.660	0.340	0.000
Q35-Q37 Cleft lip and cleft palate	0.660	0.340	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.660	0.340	0.000
Q00-Q07 Congenital malformations of the nervous system	0.660	0.340	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.659	0.340	0.000
K51.4 Pseudopolyposis of colon	0.659	0.341	0.000
B25-B34 Other viral diseases	0.657	0.343	0.000
H21 Other disorders of iris and ciliary body	0.657	0.343	0.000
Q18.1 Preauricular sinus and cyst	0.657	0.343	0.000
A80-A89 Viral infections of the central nervous system	0.656	0.343	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.656	0.344	0.000
D25 Leiomyoma of uterus	0.655	0.345	0.000
D16 Benign neoplasm of bone and articular cartilage	0.655	0.345	0.000
O21 Excessive vomiting in pregnancy	0.655	0.345	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.655	0.345	0.000
O07 Failed attempted abortion	0.655	0.345	0.000
O06 Unspecified abortion	0.655	0.345	0.000
O05 Other abortion	0.655	0.345	0.000
O01 Hydatidiform mole	0.655	0.345	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.653	0.347	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.652	0.348	0.000
E40-E46 Malnutrition	0.001	0.348	0.650
F11 Mental and behavioural disorders due to use of opioids	0.651	0.349	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.651	0.349	0.000
M02 Reactive arthropathies	0.650	0.350	0.000
M13 Other arthritis	0.649	0.351	0.000
K52 Other non-infective gastro-enteritis and colitis	0.648	0.352	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.648	0.352	0.000
L03.3 Cellulitis of trunk	0.647	0.353	0.000
A30-A49 Other bacterial diseases	0.647	0.353	0.000
M48 Other spondylopathies	0.647	0.353	0.001
M47.8 Other spondylosis	0.647	0.353	0.000
A00-A09 Intestinal infectious diseases	0.647	0.353	0.000
D29 Benign neoplasm of male genital organs	0.647	0.353	0.000
H16 Keratitis	0.646	0.353	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.646	0.354	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.645	0.355	0.000
L03.0 Cellulitis of finger and toe	0.645	0.355	0.000
M19.1 Posttraumatic arthrosis of other joints	0.644	0.356	0.000
Q12 Congenital lens malformations	0.643	0.357	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.642	0.358	0.000
M07.38 Other psoriatic arthropathies (Other)	0.642	0.358	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.642	0.358	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.642	0.358	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.642	0.358	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.642	0.358	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.642	0.358	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.642	0.358	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.642	0.358	0.000
O23 Infections of genito-urinary tract in pregnancy	0.641	0.359	0.000
F81 Specific developmental disorders of scholastic skills	0.640	0.360	0.000
F38 Other mood [affective] disorders	0.639	0.360	0.000
F34 Persistent mood [affective] disorders	0.639	0.360	0.000
F39 Unspecified mood [affective] disorder	0.639	0.360	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.638	0.361	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.362	0.638
Q50-Q56 Congenital malformations of genital organs	0.637	0.363	0.000
H54 Blindness and low vision	0.636	0.364	0.000
L43 Lichen planus	0.635	0.365	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.634	0.366	0.000
L03.2 Cellulitis of face	0.633	0.367	0.000
D11.0 Parotid gland	0.633	0.367	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.633	0.367	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.632	0.368	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.630	0.370	0.000
O04.9 Complete or unspecified, without complication	0.629	0.371	0.000
B99 Other and unspecified infectious diseases	0.629	0.371	0.000
M05.8 Other seropositive rheumatoid arthritis	0.627	0.372	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.627	0.372	0.000
M05.2 Rheumatoid vasculitis	0.627	0.372	0.000
M05.1 Rheumatoid lung disease	0.627	0.372	0.000
M05.0 Felty's syndrome	0.627	0.372	0.000
E04 Other non-toxic goitre	0.000	0.373	0.627
M15 Polyarthrosis	0.626	0.373	0.000
F31.8 Other bipolar affective disorders	0.626	0.374	0.000
F31.7 Bipolar affective disorder, currently in remission	0.626	0.374	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.626	0.374	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.626	0.374	0.000
M06.34 Rheumatoid nodule (Hand)	0.626	0.374	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.626	0.374	0.000
H10-H13 Disorders of conjunctiva	0.626	0.374	0.000
U51 Admission status on psychiatric patients	0.626	0.374	0.000
O60-O75 Complications of labour and delivery	0.625	0.375	0.000
D31 Benign neoplasm of eye and adnexa	0.624	0.376	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.624	0.376	0.000
D19 Benign neoplasm of mesothelial tissue	0.624	0.376	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.624	0.376	0.000
K65-K67 Diseases of peritoneum	0.621	0.379	0.000
M19.8 Other specified arthrosis	0.621	0.379	0.000
M19.2 Other secondary arthrosis	0.621	0.379	0.000
C50-C50 Malignant neoplasm of breast	0.621	0.379	0.000
L04 Acute lymphadenitis	0.621	0.379	0.000
L01 Impetigo	0.621	0.379	0.000
L00 Staphylococcal scalded skin syndrome	0.621	0.379	0.000
L44 Other papulosquamous disorders	0.621	0.379	0.000
L41 Parapsoriasis	0.621	0.379	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.621	0.379	0.000
L42 Pityriasis rosea	0.621	0.379	0.000
K38 Other diseases of appendix	0.620	0.380	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.620	0.380	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.620	0.380	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.618	0.382	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.616	0.384	0.000
D27 Benign neoplasm of ovary	0.615	0.385	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.615	0.385	0.000
M88 Paget's disease of bone [osteitis deformans]	0.615	0.385	0.000
K40-K46 Hernia	0.615	0.385	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.615	0.385	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.615	0.385	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.615	0.385	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.614	0.386	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.612	0.388	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.611	0.389	0.000
D33.3 Cranial nerves	0.611	0.389	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.609	0.391	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.609	0.391	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.609	0.391	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.609	0.391	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.609	0.391	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.609	0.391	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.609	0.391	0.000
H50 Other strabismus	0.608	0.391	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.608	0.392	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.608	0.392	0.000
B35 Dermatophytosis	0.608	0.392	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.606	0.394	0.000
C95 Leukaemia of unspecified cell type	0.606	0.394	0.000
C94 Other leukaemias of specified cell type	0.606	0.394	0.000
C93 Monocytic leukaemia	0.606	0.394	0.000
C88 Malignant immunoproliferative diseases	0.606	0.394	0.000
C86 Other specified types of T/NK-cell lymphoma	0.606	0.394	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.606	0.394	0.000
Q76 Congenital malformations of spine and bony thorax	0.605	0.395	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.605	0.395	0.000
L58 Radiodermatitis	0.605	0.395	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.605	0.395	0.000
L55 Sunburn	0.605	0.395	0.000
O34.4 Maternal care for other abnormalities of cervix	0.603	0.396	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.603	0.397	0.000
L05 Pilonidal cyst	0.602	0.398	0.000
O29 Complications of anaesthesia during pregnancy	0.601	0.399	0.000
O28 Abnormal findings on antenatal screening of mother	0.601	0.399	0.000
O24 Diabetes mellitus in pregnancy	0.601	0.399	0.000
O22 Venous complications in pregnancy	0.601	0.399	0.000
O25 Malnutrition in pregnancy	0.601	0.399	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.600	0.400	0.000
F33 Recurrent depressive disorder	0.600	0.400	0.000
E07.8 Other specified disorders of thyroid	0.000	0.400	0.600
E07.1 Dyshormogenetic goitre	0.000	0.400	0.600
E07.0 Hypersecretion of calcitonin	0.000	0.400	0.600
M47.1 Other spondylosis with myelopathy	0.600	0.400	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.600	0.400	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.599	0.401	0.000
H18.9 Disorder of cornea, unspecified	0.597	0.403	0.000
M47.82 Other spondylosis (Cervical region)	0.596	0.404	0.000
E15 Nondiabetic hypoglycaemic coma	0.001	0.405	0.594
M19.01 Primary arthrosis of other joints (Shoulder region)	0.594	0.406	0.000
M86 Osteomyelitis	0.594	0.406	0.000
L82 Seborrhoeic keratosis	0.594	0.406	0.000
O03.9 Complete or unspecified, without complication	0.594	0.406	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.592	0.408	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.591	0.408	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.591	0.409	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.590	0.410	0.000
O00 Ectopic pregnancy	0.590	0.410	0.000
Q17 Other congenital malformations of ear	0.588	0.412	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.588	0.412	0.000
Q15 Other congenital malformations of eye	0.588	0.412	0.000
Q14 Congenital malformations of posterior segment of eye	0.588	0.412	0.000
Q13 Congenital malformations of anterior segment of eye	0.588	0.412	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.588	0.412	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.588	0.412	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.588	0.412	0.000
O03.7 Complete or unspecified, complicated by embolism	0.588	0.412	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.588	0.412	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.588	0.412	0.000
O03.3 Incomplete, with other and unspecified complications	0.588	0.412	0.000
O03.2 Incomplete, complicated by embolism	0.588	0.412	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.588	0.412	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.588	0.412	0.000
L08 Other local infections of skin and subcutaneous tissue	0.586	0.414	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.586	0.414	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.582	0.418	0.000
Q61.3 Polycystic kidney, unspecified	0.581	0.419	0.000
L28 Lichen simplex chronicus and prurigo	0.580	0.420	0.000
K50.8 Other Crohn's disease	0.580	0.420	0.000
L51 Erythema multiforme	0.579	0.420	0.000
O43.8 Other placental disorders	0.579	0.421	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.578	0.422	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.578	0.422	0.000
Q63 Other congenital malformations of kidney	0.577	0.423	0.000
F99 Mental disorder, not otherwise specified	0.577	0.423	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.577	0.423	0.000
D26.0 Cervix uteri	0.577	0.423	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.577	0.423	0.000
F10.9 Unspecified mental and behavioural disorder	0.575	0.425	0.000
F10.8 Other mental and behavioural disorders	0.575	0.425	0.000
F10.7 Residual and late-onset psychotic disorder	0.575	0.425	0.000
F10.6 Amnesic syndrome	0.575	0.425	0.000
F10.5 Psychotic disorder	0.575	0.425	0.000
F10.4 Withdrawal state with delirium	0.575	0.425	0.000
D22.9 Melanocytic naevi, unspecified	0.575	0.425	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.575	0.425	0.000
D23 Other benign neoplasms of skin	0.574	0.426	0.000
L03.8 Cellulitis of other sites	0.573	0.427	0.000
C64-C68 Malignant neoplasms of urinary tract	0.573	0.427	0.000
K36 Other appendicitis	0.572	0.428	0.000
C91 Lymphoid leukaemia	0.571	0.429	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.571	0.429	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.571	0.429	0.000
M00 Pyogenic arthritis	0.571	0.429	0.000
C73 Malignant neoplasm of thyroid gland	0.571	0.429	0.000
D10 Benign neoplasm of mouth and pharynx	0.569	0.431	0.000
B49 Unspecified mycosis	0.569	0.431	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations