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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117293402
log Bayes Factor = 14.7593
Chromosome 6   position 110,946,140  (GRCh37) Explore rs117293402 on Ensembl!
Variant rs117293402 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter II Neoplasms
0.996 0.004 0.000
Z86 Personal history of certain other diseases
0.992 0.008 0.000
Z92 Personal history of medical treatment
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.986 0.014 0.000
R53 Malaise and fatigue
0.971 0.029 0.000
E70-E90 Metabolic disorders
0.968 0.032 0.000
K70-K77 Diseases of liver
0.965 0.035 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.964 0.036 0.000
K50-K52 Noninfective enteritis and colitis
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.961 0.039 0.000
Chapter X Diseases of the respiratory system
0.958 0.042 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.955 0.045 0.000
Z92.3 Personal history of irradiation
0.954 0.046 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.953 0.047 0.000
Z86.4 Personal history of psychoactive substance abuse
0.945 0.055 0.000
C34 Malignant neoplasm of bronchus and lung
0.941 0.059 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.940 0.060 0.000
Chapter VIII Diseases of the ear and mastoid process
0.935 0.065 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.935 0.065 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.935 0.065 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.932 0.068 0.000
E10-E14 Diabetes mellitus
0.931 0.069 0.000
Chapter XIV Diseases of the genitourinary system
0.930 0.070 0.000
S20-S29 Injuries to the thorax
0.925 0.075 0.000
Z88.6 Personal history of allergy to analgesic agent
0.925 0.075 0.000
R51 Headache
0.918 0.082 0.000
E87.5 Hyperkalaemia
0.914 0.086 0.000
R56 Convulsions, not elsewhere classified
0.913 0.087 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.907 0.093 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.906 0.094 0.000
Z98 Other postsurgical states
0.900 0.100 0.000
R60 Oedema, not elsewhere classified
0.899 0.101 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.888 0.112 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.885 0.115 0.000
R54 Senility
0.885 0.115 0.000
K50 Crohn's disease [regional enteritis]
0.884 0.116 0.000
R50 Fever of unknown origin
0.883 0.117 0.000
K70 Alcoholic liver disease
0.878 0.122 0.000
T81 Complications of procedures, not elsewhere classified
0.877 0.123 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.875 0.125 0.000
C77.1 Intrathoracic lymph nodes
0.873 0.127 0.000
Z86.7 Personal history of diseases of the circulatory system
0.871 0.129 0.000
J30-J39 Other diseases of upper respiratory tract
0.869 0.131 0.000
J40-J47 Chronic lower respiratory diseases
0.869 0.131 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.866 0.134 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.865 0.135 0.000
H90-H95 Other disorders of ear
0.865 0.135 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.864 0.136 0.000
E00-E07 Disorders of thyroid gland
0.863 0.137 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.857 0.142 0.000
N30-N39 Other diseases of urinary system
0.856 0.144 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.854 0.146 0.000
R56.8 Other and unspecified convulsions
0.852 0.148 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.851 0.149 0.000
D69 Purpura and other haemorrhagic conditions
0.850 0.150 0.000
K76 Other diseases of liver
0.848 0.152 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.848 0.152 0.000
R52 Pain, not elsewhere classified
0.847 0.153 0.000
K51 Ulcerative colitis
0.846 0.154 0.000
N10-N16 Renal tubulo-interstitial diseases
0.842 0.158 0.000
K90-K93 Other diseases of the digestive system
0.841 0.159 0.000
E86 Volume depletion
0.841 0.159 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.840 0.160 0.000
J09-J18 Influenza and pneumonia
0.838 0.162 0.000
C77.0 Lymph nodes of head, face and neck
0.838 0.162 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.837 0.163 0.000
Y43 Primarily systemic agents
0.837 0.163 0.000
Chapter VI Diseases of the nervous system
0.837 0.163 0.000
K86 Other diseases of pancreas
0.835 0.165 0.000
K50.9 Crohn's disease, unspecified
0.833 0.167 0.000
R42 Dizziness and giddiness
0.832 0.168 0.000
S00-S09 Injuries to the head
0.831 0.169 0.000
Z93 Artificial opening status
0.830 0.170 0.000
C34.3 Lower lobe, bronchus or lung
0.829 0.171 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.829 0.171 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
N60-N64 Disorders of breast
0.825 0.175 0.000
C34.9 Bronchus or lung, unspecified
0.824 0.176 0.000
C34.1 Upper lobe, bronchus or lung
0.824 0.176 0.000
C78.0 Secondary malignant neoplasm of lung
0.824 0.176 0.000
Z98.0 Intestinal bypass and anastomosis status
0.823 0.177 0.000
J44 Other chronic obstructive pulmonary disease
0.823 0.177 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.820 0.180 0.000
C78.2 Secondary malignant neoplasm of pleura
0.820 0.180 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.817 0.182 0.000
N30 Cystitis
0.817 0.183 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.815 0.185 0.000
J33 Nasal polyp
0.808 0.192 0.000
E03 Other hypothyroidism
0.808 0.192 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.804 0.196 0.000
Chapter V Mental and behavioural disorders
0.803 0.197 0.000
K40-K46 Hernia
0.801 0.199 0.000
J60-J70 Lung diseases due to external agents
0.798 0.202 0.000
H91 Other hearing loss
0.796 0.204 0.000
E11 Non-insulin-dependent diabetes mellitus
0.796 0.204 0.000
K25 Gastric ulcer
0.794 0.206 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.794 0.206 0.000
Chapter VII Diseases of the eye and adnexa
0.792 0.208 0.000
T90 Sequelae of injuries of head
0.791 0.209 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.791 0.209 0.000
R59 Enlarged lymph nodes
0.790 0.210 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
E10 Insulin-dependent diabetes mellitus
0.786 0.214 0.000
S90-S99 Injuries to the ankle and foot
0.783 0.217 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.778 0.222 0.000
R60.9 Oedema, unspecified
0.778 0.222 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.777 0.223 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.777 0.223 0.000
D70 Agranulocytosis
0.777 0.223 0.000
Chapter I Certain infectious and parasitic diseases
0.777 0.223 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.776 0.224 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.775 0.225 0.000
Z85 Personal history of malignant neoplasm
0.775 0.225 0.000
N60 Benign mammary dysplasia
0.774 0.226 0.000
J95-J99 Other diseases of the respiratory system
0.773 0.227 0.000
Chapter IX Diseases of the circulatory system
0.769 0.231 0.000
E03.9 Hypothyroidism, unspecified
0.769 0.231 0.000
Y44 Agents primarily affecting blood constituents
0.767 0.233 0.000
S06 Intracranial injury
0.767 0.233 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.767 0.233 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.766 0.234 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.765 0.235 0.000
S27 Injury of other and unspecified intrathoracic organs
0.763 0.237 0.000
E14 Unspecified diabetes mellitus
0.763 0.237 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.762 0.238 0.000
N36 Other disorders of urethra
0.762 0.238 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.762 0.238 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.762 0.238 0.000
K51.9 Ulcerative colitis, unspecified
0.760 0.240 0.000
J18 Pneumonia, organism unspecified
0.760 0.240 0.000
N30.9 Cystitis, unspecified
0.759 0.241 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.758 0.242 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.757 0.243 0.000
N17-N19 Renal failure
0.757 0.243 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.757 0.243 0.000
D00-D09 In situ neoplasms
0.757 0.243 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.756 0.243 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.755 0.245 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.754 0.246 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.752 0.248 0.000
D69.6 Thrombocytopenia, unspecified
0.752 0.248 0.000
J43 Emphysema
0.752 0.248 0.000
R68 Other general symptoms and signs
0.751 0.249 0.000
R60.0 Localised oedema
0.750 0.250 0.000
K52 Other non-infective gastro-enteritis and colitis
0.750 0.250 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.750 0.250 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.750 0.250 0.000
T66-T78 Other and unspecified effects of external causes
0.750 0.250 0.000
H91.9 Hearing loss, unspecified
0.747 0.253 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.747 0.253 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.747 0.253 0.000
K65-K67 Diseases of peritoneum
0.745 0.255 0.000
K86.8 Other specified diseases of pancreas
0.745 0.255 0.000
J33.9 Nasal polyp, unspecified
0.744 0.256 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.743 0.257 0.000
K35-K38 Diseases of appendix
0.742 0.258 0.000
R50.9 Fever, unspecified
0.741 0.259 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.741 0.259 0.000
R50.0 Fever with chills
0.739 0.261 0.000
W20-W49 Exposure to inanimate mechanical forces
0.738 0.262 0.000
K74 Fibrosis and cirrhosis of liver
0.738 0.262 0.000
Z87 Personal history of other diseases and conditions
0.737 0.263 0.000
N32 Other disorders of bladder
0.737 0.263 0.000
R47-R49 Symptoms and signs involving speech and voice
0.736 0.264 0.000
S22.4 Multiple fractures of ribs
0.736 0.264 0.000
C60-C63 Malignant neoplasms of male genital organs
0.736 0.264 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.736 0.264 0.000
H60-H62 Diseases of external ear
0.735 0.264 0.000
C80 Malignant neoplasm without specification of site
0.735 0.265 0.000
K70.3 Alcoholic cirrhosis of liver
0.734 0.265 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.733 0.267 0.000
Y52 Agents primarily affecting the cardiovascular system
0.733 0.267 0.000
E20-E35 Disorders of other endocrine glands
0.733 0.267 0.000
E87.0 Hyperosmolality and hypernatraemia
0.733 0.267 0.000
C34.0 Main bronchus
0.733 0.267 0.000
H80-H83 Diseases of inner ear
0.732 0.268 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.731 0.268 0.000
E87.6 Hypokalaemia
0.731 0.269 0.000
D80-D89 Certain disorders involving the immune mechanism
0.730 0.270 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.730 0.270 0.000
K75 Other inflammatory liver diseases
0.728 0.272 0.000
D68 Other coagulation defects
0.727 0.273 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.726 0.274 0.000
K72 Hepatic failure, not elsewhere classified
0.725 0.275 0.000
K70.9 Alcoholic liver disease, unspecified
0.725 0.275 0.000
K76.6 Portal hypertension
0.723 0.276 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.722 0.278 0.000
Z94 Transplanted organ and tissue status
0.721 0.278 0.000
K92 Other diseases of digestive system
0.721 0.279 0.000
C79 Secondary malignant neoplasm of other sites
0.721 0.279 0.000
Y43.3 Other antineoplastic drugs
0.721 0.279 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.721 0.279 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
N30.2 Other chronic cystitis
0.720 0.280 0.000
R52.0 Acute pain
0.720 0.280 0.000
S60-S69 Injuries to the wrist and hand
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.284 0.000
R62 Lack of expected normal physiological development
0.715 0.284 0.000
R57 Shock, not elsewhere classified
0.715 0.284 0.000
R64 Cachexia
0.715 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.284 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
K82 Other diseases of gallbladder
0.711 0.289 0.000
K30 Dyspepsia
0.711 0.289 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.711 0.289 0.000
Z92.9 Personal history of medical treatment, unspecified
0.708 0.291 0.000
Z92.8 Personal history of other medical treatment
0.708 0.291 0.000
Z92.5 Personal history of rehabilitation measures
0.708 0.291 0.000
Z92.0 Personal history of contraception
0.708 0.291 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
E50-E64 Other nutritional deficiencies
0.707 0.293 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.707 0.293 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.707 0.293 0.000
F30-F39 Mood [affective] disorders
0.707 0.293 0.000
J35 Chronic diseases of tonsils and adenoids
0.704 0.296 0.000
E83 Disorders of mineral metabolism
0.704 0.296 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
T91 Sequelae of injuries of neck and trunk
0.703 0.297 0.000
Y88 Sequelae of surgical and medical care as external cause
0.703 0.297 0.000
J20-J22 Other acute lower respiratory infections
0.702 0.298 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
N60.8 Other benign mammary dysplasias
0.701 0.299 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.701 0.299 0.000
K70.4 Alcoholic hepatic failure
0.701 0.299 0.000
K41 Femoral hernia
0.698 0.302 0.000
S50-S59 Injuries to the elbow and forearm
0.697 0.303 0.000
K76.9 Liver disease, unspecified
0.697 0.303 0.000
Y85 Sequelae of transport accidents
0.696 0.304 0.000
Z93.2 Ileostomy status
0.695 0.305 0.000
Y84.8 Other medical procedures
0.694 0.306 0.000
E88 Other metabolic disorders
0.694 0.306 0.000
E85 Amyloidosis
0.694 0.306 0.000
E84 Cystic fibrosis
0.694 0.306 0.000
E79 Disorders of purine and pyrimidine metabolism
0.694 0.306 0.000
E77 Disorders of glycoprotein metabolism
0.694 0.306 0.000
E76 Disorders of glycosaminoglycan metabolism
0.694 0.306 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.694 0.306 0.000
E74 Other disorders of carbohydrate metabolism
0.694 0.306 0.000
E73 Lactose intolerance
0.694 0.306 0.000
E72 Other disorders of amino-acid metabolism
0.694 0.306 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.694 0.306 0.000
E70 Disorders of aromatic amino-acid metabolism
0.694 0.306 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.694 0.306 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.693 0.307 0.000
K77 Liver disorders in diseases classified elsewhere
0.692 0.308 0.000
K73 Chronic hepatitis, not elsewhere classified
0.692 0.308 0.000
K71 Toxic liver disease
0.692 0.308 0.000
S40-S49 Injuries to the shoulder and upper arm
0.692 0.308 0.000
E87.2 Acidosis
0.691 0.309 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.691 0.309 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.691 0.309 0.000
C32 Malignant neoplasm of larynx
0.691 0.309 0.000
C31 Malignant neoplasm of accessory sinuses
0.691 0.309 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.691 0.309 0.000
C37 Malignant neoplasm of thymus
0.691 0.309 0.000
C33 Malignant neoplasm of trachea
0.691 0.309 0.000
R52.1 Chronic intractable pain
0.690 0.310 0.000
Z98.1 Arthrodesis status
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.689 0.311 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.686 0.314 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.686 0.314 0.000
S70-S79 Injuries to the hip and thigh
0.685 0.315 0.000
Y59 Other and unspecified vaccines and biological substances
0.685 0.315 0.000
Y58 Bacterial vaccines
0.685 0.315 0.000
Y57 Other and unspecified drugs and medicaments
0.685 0.315 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.685 0.315 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.685 0.315 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.685 0.315 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.685 0.315 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
Y48 Anaesthetics and therapeutic gases
0.685 0.315 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.685 0.315 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.685 0.315 0.000
E16 Other disorders of pancreatic internal secretion
0.684 0.316 0.000
S02 Fracture of skull and facial bones
0.684 0.316 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.683 0.317 0.000
G40-G47 Episodic and paroxysmal disorders
0.683 0.317 0.000
S80-S89 Injuries to the knee and lower leg
0.683 0.317 0.000
J69 Pneumonitis due to solids and liquids
0.682 0.317 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.682 0.318 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.681 0.319 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.680 0.319 0.000
Y40 Systemic antibiotics
0.680 0.320 0.000
J30 Vasomotor and allergic rhinitis
0.680 0.320 0.000
Y86 Sequelae of other accidents
0.679 0.320 0.000
H90 Conductive and sensorineural hearing loss
0.679 0.321 0.000
Z86.0 Personal history of other neoplasms
0.679 0.321 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.677 0.323 0.000
N61 Inflammatory disorders of breast
0.675 0.325 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.674 0.326 0.000
C34.8 Overlapping lesion of bronchus and lung
0.674 0.326 0.000
C34.2 Middle lobe, bronchus or lung
0.674 0.326 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.674 0.326 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.674 0.326 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.674 0.326 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.674 0.326 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.674 0.326 0.000
E11.4 With neurological complications
0.674 0.326 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.674 0.326 0.000
Z87.1 Personal history of diseases of the digestive system
0.672 0.328 0.000
K50.1 Crohn's disease of large intestine
0.672 0.328 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.672 0.328 0.000
Z91.5 Personal history of self-harm
0.671 0.329 0.000
T87 Complications peculiar to reattachment and amputation
0.670 0.330 0.000
T86 Failure and rejection of transplanted organs and tissues
0.670 0.330 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.670 0.330 0.000
E87.4 Mixed disorder of acid-base balance
0.670 0.330 0.000
E87.3 Alkalosis
0.670 0.330 0.000
J18.0 Bronchopneumonia, unspecified
0.670 0.330 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.670 0.330 0.000
V10-V19 Pedal cyclist injured in transport accident
0.669 0.331 0.000
G81 Hemiplegia
0.669 0.331 0.000
S22.0 Fracture of thoracic vertebra
0.668 0.332 0.000
C77.8 Lymph nodes of multiple regions
0.668 0.332 0.000
C77.4 Inguinal and lower limb lymph nodes
0.668 0.332 0.000
J43.9 Emphysema, unspecified
0.668 0.332 0.000
E13 Other specified diabetes mellitus
0.667 0.333 0.000
E12 Malnutrition-related diabetes mellitus
0.667 0.333 0.000
K51.4 Pseudopolyposis of colon
0.667 0.333 0.000
D73 Diseases of spleen
0.666 0.334 0.000
Y43.4 Immunosuppressive agents
0.665 0.334 0.000
K86.2 Cyst of pancreas
0.665 0.335 0.000
K86.9 Disease of pancreas, unspecified
0.664 0.336 0.000
J36 Peritonsillar abscess
0.664 0.336 0.000
S29 Other and unspecified injuries of thorax
0.663 0.337 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.663 0.337 0.000
S26 Injury of heart
0.663 0.337 0.000
S25 Injury of blood vessels of thorax
0.663 0.337 0.000
S24 Injury of nerves and spinal cord at thorax level
0.663 0.337 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.663 0.337 0.000
S21 Open wound of thorax
0.663 0.337 0.000
S20 Superficial injury of thorax
0.663 0.337 0.000
Q60-Q64 Congenital malformations of the urinary system
0.663 0.337 0.000
K85 Acute pancreatitis
0.662 0.338 0.000
S22.40 Multiple fractures of ribs (closed)
0.662 0.338 0.000
C01 Malignant neoplasm of base of tongue
0.660 0.340 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.660 0.340 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.660 0.340 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.659 0.341 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.659 0.341 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.658 0.342 0.000
M65-M68 Disorders of synovium and tendon
0.658 0.342 0.000
M80-M85 Disorders of bone density and structure
0.658 0.342 0.000
C15-C26 Malignant neoplasms of digestive organs
0.657 0.343 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.657 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.657 0.343 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.656 0.344 0.000
Z88.5 Personal history of allergy to narcotic agent
0.655 0.345 0.000
R56.0 Febrile convulsions
0.654 0.346 0.000
N17 Acute renal failure
0.654 0.346 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.654 0.346 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.654 0.346 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.653 0.347 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.652 0.347 0.000
R59.1 Generalised enlarged lymph nodes
0.652 0.348 0.000
C78.7 Secondary malignant neoplasm of liver
0.652 0.348 0.000
T92 Sequelae of injuries of upper limb
0.652 0.348 0.000
H10-H13 Disorders of conjunctiva
0.651 0.349 0.000
R45 Symptoms and signs involving emotional state
0.651 0.349 0.000
R61 Hyperhidrosis
0.650 0.349 0.000
K83 Other diseases of biliary tract
0.650 0.350 0.000
D67 Hereditary factor IX deficiency
0.650 0.350 0.000
D66 Hereditary factor VIII deficiency
0.650 0.350 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.650 0.350 0.000
J98 Other respiratory disorders
0.649 0.351 0.000
J46 Status asthmaticus
0.649 0.351 0.000
C64-C68 Malignant neoplasms of urinary tract
0.648 0.352 0.000
E14.9 Without complications
0.647 0.352 0.000
S27.0 Traumatic pneumothorax
0.647 0.353 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.647 0.353 0.000
G90-G99 Other disorders of the nervous system
0.646 0.354 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.646 0.354 0.000
T90.5 Sequelae of intracranial injury
0.646 0.354 0.000
N36.8 Other specified disorders of urethra
0.645 0.355 0.000
R60.1 Generalised oedema
0.645 0.355 0.000
D37.4 Colon
0.644 0.356 0.000
S22.2 Fracture of sternum
0.644 0.356 0.000
N00-N08 Glomerular diseases
0.644 0.356 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.643 0.357 0.000
Z83 Family history of other specific disorders
0.642 0.357 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.642 0.357 0.000
W00-W19 Falls
0.642 0.358 0.000
C77.9 Lymph node, unspecified
0.641 0.359 0.000
Y84.0 Cardiac catheterisation
0.641 0.359 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T93 Sequelae of injuries of lower limb
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.641 0.359 0.000
Z97 Presence of other devices
0.640 0.360 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.640 0.360 0.000
Z95.1 Presence of aortocoronary bypass graft
0.640 0.360 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.640 0.360 0.000
N36.2 Urethral caruncle
0.639 0.361 0.000
N99-N99 Other disorders of the genitourinary system
0.638 0.362 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.637 0.363 0.000
Y45.1 Salicylates
0.637 0.363 0.000
R46 Symptoms and signs involving appearance and behaviour
0.637 0.363 0.000
R43 Disturbances of smell and taste
0.637 0.363 0.000
E10.1 With ketoacidosis
0.637 0.363 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.636 0.364 0.000
T90.4 Sequelae of injury of eye and orbit
0.636 0.364 0.000
N60.0 Solitary cyst of breast
0.636 0.364 0.000
K90 Intestinal malabsorption
0.635 0.365 0.000
K92.0 Haematemesis
0.635 0.365 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.635 0.365 0.000
R63 Symptoms and signs concerning food and fluid intake
0.635 0.365 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.635 0.365 0.000
Z72 Problems related to lifestyle
0.634 0.366 0.000
K50.8 Other Crohn's disease
0.634 0.366 0.000
R50.8 Other specified fever
0.633 0.367 0.000
R50.2 Drug-induced fever
0.633 0.367 0.000
R50.1 Persistent fever
0.633 0.367 0.000
D60-D64 Aplastic and other anaemias
0.633 0.367 0.000
C77.5 Intrapelvic lymph nodes
0.633 0.367 0.000
C51-C58 Malignant neoplasms of female genital organs
0.633 0.367 0.000
Y44.2 Anticoagulants
0.633 0.367 0.000
K43 Ventral hernia
0.631 0.369 0.000
K82.4 Cholesterolosis of gallbladder
0.631 0.369 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.630 0.370 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.630 0.370 0.000
H65-H75 Diseases of middle ear and mastoid
0.630 0.370 0.000
K40 Inguinal hernia
0.630 0.370 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.629 0.371 0.000
K70.1 Alcoholic hepatitis
0.629 0.371 0.000
K70.0 Alcoholic fatty liver
0.629 0.371 0.000
J33.0 Polyp of nasal cavity
0.629 0.371 0.000
C09 Malignant neoplasm of tonsil
0.629 0.371 0.000
S92 Fracture of foot, except ankle
0.629 0.371 0.000
T81.9 Unspecified complication of procedure
0.629 0.371 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.629 0.371 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.629 0.371 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.629 0.371 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.629 0.371 0.000
H92 Otalgia and effusion of ear
0.627 0.373 0.000
T90.9 Sequelae of unspecified injury of head
0.627 0.373 0.000
N60.4 Mammary duct ectasia
0.627 0.373 0.000
R40 Somnolence, stupor and coma
0.627 0.373 0.000
K86.1 Other chronic pancreatitis
0.626 0.374 0.000
E65-E68 Obesity and other hyperalimentation
0.626 0.374 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.626 0.374 0.000
E10.9 Without complications
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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