TreeWAS – Variant ID: rs11740474

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I21.4 Acute subendocardial myocardial infarction	0.000	0.877	0.123
R52.2 Other chronic pain	0.090	0.910	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.942	0.058
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.942	0.058
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.943	0.057
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.943	0.057
T43.2 Other and unspecified antidepressants	0.000	0.946	0.054
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.947	0.053
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.947	0.053
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.949	0.051
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.952	0.048
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.952	0.048
T46.1 Calcium-channel blockers	0.000	0.952	0.048
T50.8 Diagnostic agents	0.000	0.952	0.048
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.953	0.047
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.953	0.047
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.954	0.046
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.954	0.046
T36 Poisoning by systemic antibiotics	0.000	0.954	0.046
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.955	0.045
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.956	0.044
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.956	0.044
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.956	0.044
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.957	0.042
T50.7 Analeptics and opioid receptor antagonists	0.000	0.958	0.042
T50.5 Appetite depressants	0.000	0.958	0.042
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.958	0.042
T50.1 Loop [high-ceiling] diuretics	0.000	0.958	0.042
T50.0 Mineralocorticoids and their antagonists	0.000	0.958	0.042
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.958	0.041
T50.4 Drugs affecting uric acid metabolism	0.000	0.959	0.041
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.959	0.041
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.959	0.041
T43.9 Psychotropic drug, unspecified	0.000	0.959	0.041
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.959	0.041
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.959	0.041
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.959	0.041
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.960	0.040
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.960	0.040
M06.9 Rheumatoid arthritis, unspecified	0.000	0.960	0.040
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.961	0.039
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.961	0.039
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.962	0.038
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.962	0.038
T46.7 Peripheral vasodilators	0.000	0.962	0.038
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.962	0.038
T39.4 Antirheumatics, not elsewhere classified	0.000	0.962	0.038
T39.2 Pyrazolone derivatives	0.000	0.962	0.038
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.962	0.038
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.963	0.037
T36.0 Penicillins	0.000	0.963	0.037
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.963	0.037
T45.0 Antiallergic and antiemetic drugs	0.000	0.964	0.036
T42.4 Benzodiazepines	0.000	0.964	0.036
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.965	0.035
T43.6 Psychostimulants with abuse potential	0.000	0.966	0.034
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.966	0.034
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.966	0.034
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.966	0.034
T38.9 Other and unspecified hormone antagonists	0.000	0.967	0.033
T38.7 Androgens and anabolic congeners	0.000	0.967	0.033
T38.5 Other oestrogens and progestogens	0.000	0.967	0.033
T38.4 Oral contraceptives	0.000	0.967	0.033
T38.2 Antithyroid drugs	0.000	0.967	0.033
T38.0 Glucocorticoids and synthetic analogues	0.000	0.967	0.033
T45.2 Vitamins, not elsewhere classified	0.000	0.967	0.033
T45.5 Anticoagulants	0.000	0.967	0.033
T36.4 Tetracyclines	0.000	0.967	0.033
T36.9 Systemic antibiotic, unspecified	0.000	0.967	0.033
T36.8 Other systemic antibiotics	0.000	0.967	0.033
T36.7 Antifungal antibiotics, systemically used	0.000	0.967	0.033
T36.6 Rifamycins	0.000	0.967	0.033
T36.5 Aminoglycosides	0.000	0.967	0.033
T36.3 Macrolides	0.000	0.967	0.033
T36.2 Chloramphenicol group	0.000	0.967	0.033
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.967	0.033
M06.3 Rheumatoid nodule	0.000	0.967	0.033
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.967	0.032
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.968	0.032
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.968	0.032
T48.5 Anti-common-cold drugs	0.000	0.968	0.032
T48.4 Expectorants	0.000	0.968	0.032
T48.3 Antitussives	0.000	0.968	0.032
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.968	0.032
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.968	0.032
T48.0 Oxytocic drugs	0.000	0.968	0.032
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.968	0.032
M06 Other rheumatoid arthritis	0.000	0.968	0.032
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.968	0.031
T45.8 Other primarily systemic and haematological agents	0.000	0.968	0.031
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.968	0.031
T45.6 Fibrinolysis-affecting drugs	0.000	0.968	0.031
T45.4 Iron and its compounds	0.000	0.968	0.031
T45.3 Enzymes, not elsewhere classified	0.000	0.968	0.031
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.969	0.031
T38.1 Thyroid hormones and substitutes	0.000	0.969	0.031
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.969	0.031
M06.34 Rheumatoid nodule (Hand)	0.000	0.969	0.031
T41.5 Therapeutic gases	0.000	0.970	0.030
T41.4 Anaesthetic, unspecified	0.000	0.970	0.030
T41.3 Local anaesthetics	0.000	0.970	0.030
T41.2 Other and unspecified general anaesthetics	0.000	0.970	0.030
T41.1 Intravenous anaesthetics	0.000	0.970	0.030
T41.0 Inhaled anaesthetics	0.000	0.970	0.030
T49.9 Topical agent, unspecified	0.000	0.970	0.030
T49.8 Other topical agents	0.000	0.970	0.030
T49.7 Dental drugs, topically applied	0.000	0.970	0.030
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.970	0.030
T49.5 Ophthalmological drugs and preparations	0.000	0.970	0.030
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.970	0.030
T49.3 Emollients, demulcents and protectants	0.000	0.970	0.030
T49.2 Local astringents and local detergents	0.000	0.970	0.030
T49.1 Antipruritics	0.000	0.970	0.030
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.970	0.030
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.971	0.029
T37.5 Antiviral drugs	0.000	0.971	0.029
T37.4 Anthelminthics	0.000	0.971	0.029
T37.3 Other antiprotozoal drugs	0.000	0.971	0.029
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.971	0.029
T37.1 Antimycobacterial drugs	0.000	0.971	0.029
T37.0 Sulphonamides	0.000	0.971	0.029
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.971	0.029
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.971	0.029
T39.0 Salicylates	0.000	0.971	0.029
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.971	0.029
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.971	0.028
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.972	0.028
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.972	0.028
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.972	0.028
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.972	0.028
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.972	0.028
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.972	0.028
T44.0 Anticholinesterase agents	0.000	0.972	0.028
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.972	0.028
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.972	0.028
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.972	0.028
T39.1 4-Aminophenol derivatives	0.000	0.972	0.028
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.973	0.027
T42.3 Barbiturates	0.000	0.973	0.027
T42.2 Succinimides and oxazolidinediones	0.000	0.973	0.027
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.974	0.026
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.974	0.026
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.976	0.024
T47.4 Other laxatives	0.000	0.976	0.023
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.976	0.023
M06.38 Rheumatoid nodule (Other)	0.000	0.976	0.023
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.976	0.023
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.976	0.023
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.976	0.023
T42.0 Hydantoin derivatives	0.000	0.977	0.023
M06.2 Rheumatoid bursitis	0.000	0.977	0.023
M06.1 Adult-onset Still's disease	0.000	0.977	0.023
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.977	0.023
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.977	0.023
T47.7 Emetics	0.000	0.977	0.023
T47.5 Digestants	0.000	0.977	0.023
T47.3 Saline and osmotic laxatives	0.000	0.977	0.023
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.977	0.023
T42.1 Iminostilbenes	0.000	0.977	0.022
M06.33 Rheumatoid nodule (Forearm)	0.000	0.978	0.022
M06.0 Seronegative rheumatoid arthritis	0.000	0.978	0.022
M06.8 Other specified rheumatoid arthritis	0.000	0.978	0.021
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.978	0.021
T47.6 Antidiarrhoeal drugs	0.000	0.979	0.021
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.979	0.021
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.021	0.979	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.979	0.021
T47.0 Histamine H(2)-receptor antagonists	0.000	0.979	0.020
T47.2 Stimulant laxatives	0.000	0.980	0.020
M06.4 Inflammatory polyarthropathy	0.000	0.980	0.020
R52 Pain, not elsewhere classified	0.019	0.981	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.981	0.019
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.981	0.019
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.982	0.018
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.982	0.018
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.983	0.017
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.983	0.017
M06.18 Adult-onset Still's disease (Other)	0.000	0.983	0.017
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.983	0.017
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.983	0.017
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.983	0.017
M06.14 Adult-onset Still's disease (Hand)	0.000	0.983	0.017
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.983	0.017
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.983	0.017
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.983	0.017
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.983	0.017
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.983	0.017
M06.28 Rheumatoid bursitis (Other)	0.000	0.983	0.017
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.983	0.017
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.983	0.017
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.983	0.017
M06.24 Rheumatoid bursitis (Hand)	0.000	0.983	0.017
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.983	0.017
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.983	0.017
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.983	0.017
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.983	0.017
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.983	0.017
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.984	0.016
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.984	0.016
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.984	0.016
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.984	0.016
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.984	0.016
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.984	0.016
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.984	0.016
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.984	0.016
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.984	0.016
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.984	0.016
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.984	0.016
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.984	0.016
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.984	0.016
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.984	0.016
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.984	0.015
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.985	0.015
T40.2 Other opioids	0.000	0.985	0.015
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.985	0.014
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.985	0.014
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.985	0.014
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.985	0.014
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.985	0.014
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.985	0.014
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.985	0.014
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.986	0.014
R52.1 Chronic intractable pain	0.014	0.986	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.986	0.014
T40.8 Lysergide [LSD]	0.000	0.986	0.014
T40.7 Cannabis (derivatives)	0.000	0.986	0.014
T40.0 Opium	0.000	0.986	0.014
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.987	0.013
R52.9 Pain, unspecified	0.013	0.987	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.987	0.013
T40.5 Cocaine	0.000	0.987	0.013
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.987	0.013
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.988	0.012
T40.3 Methadone	0.000	0.988	0.012
T40.6 Other and unspecified narcotics	0.000	0.988	0.012
T40.1 Heroin	0.000	0.988	0.011
M19.99 Arthrosis, unspecified (Site unspecified)	0.000	0.990	0.010
M79.79 Fibromyalgia (Site unspecified)	0.000	0.990	0.010
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
N17.9 Acute renal failure, unspecified	0.000	0.990	0.010
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.991	0.009
F45.8 Other somatoform disorders	0.009	0.991	0.000
F45.3 Somatoform autonomic dysfunction	0.008	0.992	0.000
F45 Somatoform disorders	0.008	0.992	0.000
M48.0 Spinal stenosis	0.000	0.993	0.007
M48.02 Spinal stenosis (Cervical region)	0.000	0.993	0.007
F45.9 Somatoform disorder, unspecified	0.007	0.993	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.007	0.993	0.000
R52.0 Acute pain	0.007	0.993	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
F45.2 Hypochondriacal disorder	0.007	0.993	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.993	0.007
T40.4 Other synthetic narcotics	0.001	0.993	0.006
M48.04 Spinal stenosis (Thoracic region)	0.000	0.994	0.006
F45.4 Persistent somatoform pain disorder	0.006	0.994	0.000
F45.1 Undifferentiated somatoform disorder	0.006	0.994	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.994	0.006
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
M79.7 Fibromyalgia	0.000	0.994	0.006
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.994	0.005
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.994	0.005
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.994	0.005
C71.1 Frontal lobe	0.006	0.994	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.994	0.005
F45.0 Somatisation disorder	0.005	0.995	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.995	0.005
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
E66.9 Obesity, unspecified	0.000	0.995	0.005
V49 Car occupant injured in other and unspecified transport accidents	0.005	0.995	0.000
H40.8 Other glaucoma	0.005	0.995	0.000
M79.70 Fibromyalgia (Multiple sites)	0.000	0.995	0.005
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.005	0.995	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.995	0.005
F31 Bipolar affective disorder	0.000	0.995	0.005
A41.5 Septicaemia due to other Gram-negative organisms	0.005	0.995	0.000
E66.8 Other obesity	0.000	0.995	0.005
F31.9 Bipolar affective disorder, unspecified	0.000	0.996	0.004
E66 Obesity	0.000	0.996	0.004
M79.78 Fibromyalgia (Other)	0.000	0.996	0.004
M79.77 Fibromyalgia (Ankle and foot)	0.000	0.996	0.004
M79.76 Fibromyalgia (Lower leg)	0.000	0.996	0.004
M79.75 Fibromyalgia (Pelvic region and thigh)	0.000	0.996	0.004
M79.74 Fibromyalgia (Hand)	0.000	0.996	0.004
M79.73 Fibromyalgia (Forearm)	0.000	0.996	0.004
M79.72 Fibromyalgia (Upper arm)	0.000	0.996	0.004
M79.71 Fibromyalgia (Shoulder region)	0.000	0.996	0.004
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.996	0.004
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.004	0.996	0.000
F31.8 Other bipolar affective disorders	0.000	0.996	0.004
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.004	0.996	0.000
V49.8 Car occupant [any] injured in other specified transport accidents	0.004	0.996	0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.004	0.996	0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.004	0.996	0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.004	0.996	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.004	0.996	0.000
O62.3 Precipitate labour	0.000	0.996	0.004
C71 Malignant neoplasm of brain	0.004	0.996	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.996	0.004
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.996	0.004
C50.8 Overlapping lesion of breast	0.000	0.996	0.004
E61.1 Iron deficiency	0.004	0.996	0.000
M75.5 Bursitis of shoulder	0.000	0.996	0.004
R22.0 Localised swelling, mass and lump, head	0.000	0.997	0.003
C71.5 Cerebral ventricle	0.003	0.997	0.000
E66.1 Drug-induced obesity	0.000	0.997	0.003
F22.0 Delusional disorder	0.003	0.997	0.000
M21.27 Flexion deformity (Ankle and foot)	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
J93.9 Pneumothorax, unspecified	0.003	0.997	0.000
S52.20 Fracture of shaft of ulna (closed)	0.003	0.997	0.000
C71.4 Occipital lobe	0.003	0.997	0.000
G95.0 Syringomyelia and syringobulbia	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.997	0.003
V49.81 Car occupant injured in trnsp accident w military vehicle (Car occupant (driver) (passenger) injured in transport accident with military vehicle)	0.003	0.997	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
D13.2 Duodenum	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
O62 Abnormalities of forces of labour	0.000	0.997	0.003
M21.24 Flexion deformity (Hand)	0.003	0.997	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.003	0.997	0.000
M21.2 Flexion deformity	0.003	0.997	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.003	0.997	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.997	0.003
O62.0 Primary inadequate contractions	0.000	0.997	0.003
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
M48 Other spondylopathies	0.000	0.997	0.003
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
M50.1 Cervical disk disorder with radiculopathy	0.000	0.997	0.003
Z63.4 Disappearance and death of family member	0.000	0.997	0.003
N60.3 Fibrosclerosis of breast	0.000	0.997	0.003
N17 Acute renal failure	0.000	0.997	0.003
L91.8 Other hypertrophic disorders of skin	0.000	0.997	0.003
E66.0 Obesity due to excess calories	0.000	0.997	0.002
C25.9 Pancreas, unspecified	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.997	0.000
C25.0 Head of pancreas	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.002	0.997	0.000
O62.1 Secondary uterine inertia	0.000	0.997	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.002
Z97.8 Presence of other specified devices	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.997	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.997	0.002
O62.8 Other abnormalities of forces of labour	0.000	0.998	0.002
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.000
M21.28 Flexion deformity (Other)	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.002	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.002	0.998	0.000
O95 Obstetric death of unspecified cause	0.002	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.998	0.002
M48.4 Fatigue fracture of vertebra	0.000	0.998	0.002
M48.3 Traumatic spondylopathy	0.000	0.998	0.002
M48.2 Kissing spine	0.000	0.998	0.002
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.998	0.002
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.998	0.002
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.998	0.002
D48.1 Connective and other soft tissue	0.002	0.998	0.000
G24.5 Blepharospasm	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
N17.2 Acute renal failure with medullary necrosis	0.000	0.998	0.002
F22 Persistent delusional disorders	0.002	0.998	0.000
M48.8 Other specified spondylopathies	0.000	0.998	0.002
O62.9 Abnormality of forces of labour, unspecified	0.000	0.998	0.002
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.000	0.998	0.002
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
C25.2 Tail of pancreas	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
M48.9 Spondylopathy, unspecified	0.000	0.998	0.002
M75.3 Calcific tendinitis of shoulder	0.000	0.998	0.002
S02.3 Fracture of orbital floor	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.998	0.002
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.998	0.002
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.998	0.002
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.000	0.998	0.002
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.000	0.998	0.002
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.000	0.998	0.002
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.000	0.998	0.002
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.000	0.998	0.002
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.000	0.998	0.002
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.000	0.998	0.002
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.000	0.998	0.002
M48.29 Kissing spine (Site unspecified)	0.000	0.998	0.002
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.27 Kissing spine (Lumbosacral region)	0.000	0.998	0.002
M48.26 Kissing spine (Lumbar region)	0.000	0.998	0.002
M48.25 Kissing spine (Thoracolumbar region)	0.000	0.998	0.002
M48.24 Kissing spine (Thoracic region)	0.000	0.998	0.002
M48.23 Kissing spine (Cervicothoracic region)	0.000	0.998	0.002
M48.22 Kissing spine (Cervical region)	0.000	0.998	0.002
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.20 Kissing spine (Multiple sites in spine)	0.000	0.998	0.002
M48.39 Traumatic spondylopathy (Site unspecified)	0.000	0.998	0.002
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.000	0.998	0.002
M48.36 Traumatic spondylopathy (Lumbar region)	0.000	0.998	0.002
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.000	0.998	0.002
M48.34 Traumatic spondylopathy (Thoracic region)	0.000	0.998	0.002
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.000	0.998	0.002
M48.32 Traumatic spondylopathy (Cervical region)	0.000	0.998	0.002
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.000	0.998	0.002
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.000	0.998	0.002
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.000	0.998	0.002
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.000	0.998	0.002
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.000	0.998	0.002
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.000	0.998	0.002
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.000	0.998	0.002
M48.42 Fatigue fracture of vertebra (Cervical region)	0.000	0.998	0.002
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.000	0.998	0.002
G24 Dystonia	0.000	0.998	0.002
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.998	0.002
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.998	0.002
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
A41 Other septicaemia	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
G24.3 Spasmodic torticollis	0.000	0.998	0.002
L70.0 Acne vulgaris	0.000	0.998	0.002
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.000	0.998	0.002
G57.8 Other mononeuropathies of lower limb	0.000	0.998	0.002
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
S52.2 Fracture of shaft of ulna	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.000	0.998	0.002
G95 Other diseases of spinal cord	0.002	0.998	0.000
F22.8 Other persistent delusional disorders	0.002	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.000	0.998	0.002
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.000	0.998	0.002
M48.84 Other specified spondylopathies (Thoracic region)	0.000	0.998	0.002
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.000	0.998	0.002
M48.82 Other specified spondylopathies (Cervical region)	0.000	0.998	0.002
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.000	0.998	0.002
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
G24.8 Other dystonia	0.000	0.998	0.002
M21 Other acquired deformities of limbs	0.002	0.998	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.998	0.002
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
A41.8 Other specified septicaemia	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.000	0.998	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations