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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117446263
log Bayes Factor = 22.5816
Chromosome 6   position 160,847,571  (GRCh37) Explore rs117446263 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
E78.5 Hyperlipidaemia, unspecified
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
I35 Nonrheumatic aortic valve disorders
0.999 0.001 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.998 0.002 0.000
I25.2 Old myocardial infarction
0.998 0.002 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.997 0.003 0.000
I35.0 Aortic (valve) stenosis
0.995 0.005 0.000
I21.9 Acute myocardial infarction, unspecified
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.994 0.006 0.000
Z95.1 Presence of aortocoronary bypass graft
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
E11 Non-insulin-dependent diabetes mellitus
0.984 0.016 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.974 0.026 0.000
E11.9 Without complications
0.969 0.031 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.964 0.036 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.963 0.037 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.954 0.046 0.000
Chapter XX External causes of morbidity and mortality
0.947 0.053 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.946 0.054 0.000
I20 Angina pectoris
0.941 0.059 0.000
I05-I09 Chronic rheumatic heart diseases
0.939 0.061 0.000
I21.4 Acute subendocardial myocardial infarction
0.936 0.064 0.000
I22 Subsequent myocardial infarction
0.933 0.066 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.930 0.070 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.929 0.071 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.921 0.079 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.914 0.086 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.913 0.087 0.000
I08 Multiple valve diseases
0.901 0.099 0.000
I44 Atrioventricular and left bundle-branch block
0.894 0.106 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.887 0.113 0.000
Z95.4 Presence of other heart-valve replacement
0.886 0.114 0.000
I50 Heart failure
0.886 0.114 0.000
Chapter I Certain infectious and parasitic diseases
0.883 0.117 0.000
I20.9 Angina pectoris, unspecified
0.882 0.118 0.000
Z95.3 Presence of xenogenic heart valve
0.875 0.125 0.000
I45 Other conduction disorders
0.866 0.134 0.000
Z72 Problems related to lifestyle
0.865 0.135 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.857 0.143 0.000
I44.7 Left bundle-branch block, unspecified
0.847 0.153 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.847 0.153 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.847 0.153 0.000
Chapter XXII Codes for special purposes
0.837 0.163 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.836 0.164 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.826 0.174 0.000
I73 Other peripheral vascular diseases
0.822 0.178 0.000
O36 Maternal care for other known or suspected foetal problems
0.821 0.179 0.000
E14 Unspecified diabetes mellitus
0.810 0.190 0.000
I35.1 Aortic (valve) insufficiency
0.806 0.194 0.000
E11.3 With ophthalmic complications
0.802 0.198 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.799 0.201 0.000
I60-I69 Cerebrovascular diseases
0.799 0.201 0.000
E10 Insulin-dependent diabetes mellitus
0.797 0.203 0.000
W20-W49 Exposure to inanimate mechanical forces
0.794 0.206 0.000
E65-E68 Obesity and other hyperalimentation
0.793 0.207 0.000
I50.9 Heart failure, unspecified
0.791 0.209 0.000
E73 Lactose intolerance
0.790 0.210 0.000
I35.9 Aortic valve disorder, unspecified
0.789 0.211 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.788 0.212 0.000
I30 Acute pericarditis
0.786 0.214 0.000
I49 Other cardiac arrhythmias
0.786 0.214 0.000
Z72.1 Alcohol use
0.783 0.217 0.000
I73.9 Peripheral vascular disease, unspecified
0.777 0.223 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.777 0.223 0.000
I72 Other aneurysm
0.774 0.226 0.000
Z80 Family history of malignant neoplasm
0.773 0.227 0.000
B95-B98 Bacterial, viral and other infectious agents
0.771 0.229 0.000
B15-B19 Viral hepatitis
0.770 0.230 0.000
O80-O84 Delivery
0.769 0.231 0.000
I38 Endocarditis, valve unspecified
0.768 0.232 0.000
O85-O92 Complications predominantly related to the puerperium
0.767 0.233 0.000
E11.4 With neurological complications
0.767 0.233 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.766 0.234 0.000
I60 Subarachnoid haemorrhage
0.764 0.236 0.000
Z92 Personal history of medical treatment
0.762 0.238 0.000
I20.8 Other forms of angina pectoris
0.761 0.239 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.761 0.239 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.754 0.246 0.000
W50-W64 Exposure to animate mechanical forces
0.754 0.246 0.000
I35.8 Other aortic valve disorders
0.753 0.247 0.000
Z22 Carrier of infectious disease
0.753 0.247 0.000
I44.3 Other and unspecified atrioventricular block
0.753 0.247 0.000
I45.9 Conduction disorder, unspecified
0.752 0.248 0.000
I36 Nonrheumatic tricuspid valve disorders
0.750 0.250 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.748 0.252 0.000
E78.2 Mixed hyperlipidaemia
0.747 0.253 0.000
I08.0 Disorders of both mitral and aortic valves
0.746 0.254 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.744 0.256 0.000
O47 False labour
0.741 0.259 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.741 0.259 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.740 0.259 0.000
I74 Arterial embolism and thrombosis
0.739 0.261 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.738 0.262 0.000
E20-E35 Disorders of other endocrine glands
0.737 0.263 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.737 0.263 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.735 0.264 0.000
O36.5 Maternal care for poor foetal growth
0.734 0.266 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
I08.8 Other multiple valve diseases
0.728 0.272 0.000
Z75 Problems related to medical facilities and other health care
0.727 0.273 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.726 0.274 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.725 0.274 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.724 0.276 0.000
W00-W19 Falls
0.723 0.277 0.000
E88 Other metabolic disorders
0.723 0.277 0.000
E78.8 Other disorders of lipoprotein metabolism
0.722 0.278 0.000
Z72.2 Drug use
0.722 0.278 0.000
Z73 Problems related to life-management difficulty
0.722 0.278 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.721 0.279 0.000
Q60-Q64 Congenital malformations of the urinary system
0.720 0.280 0.000
Z74 Problems related to care-provider dependency
0.719 0.281 0.000
E11.2 With renal complications
0.719 0.281 0.000
E11.1 With ketoacidosis
0.718 0.282 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.718 0.282 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
O24 Diabetes mellitus in pregnancy
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.4 Other hyperlipidaemia
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.712 0.288 0.000
I70 Atherosclerosis
0.712 0.288 0.000
E13 Other specified diabetes mellitus
0.712 0.288 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.712 0.288 0.000
E11.5 With peripheral circulatory complications
0.712 0.288 0.000
I71 Aortic aneurysm and dissection
0.711 0.289 0.000
O36.8 Maternal care for other specified foetal problems
0.708 0.292 0.000
E11.8 With unspecified complications
0.705 0.295 0.000
E11.7 With multiple complications
0.705 0.295 0.000
E11.6 With other specified complications
0.705 0.295 0.000
E11.0 With coma
0.705 0.295 0.000
I25.3 Aneurysm of heart
0.704 0.296 0.000
I20.1 Angina pectoris with documented spasm
0.699 0.301 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.699 0.301 0.000
Z84 Family history of other conditions
0.698 0.302 0.000
Z81 Family history of mental and behavioural disorders
0.698 0.302 0.000
Z97 Presence of other devices
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
I33 Acute and subacute endocarditis
0.695 0.305 0.000
Z80.3 Family history of malignant neoplasm of breast
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
Z76 Persons encountering health services in other circumstances
0.690 0.310 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.690 0.310 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.690 0.310 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.690 0.310 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.690 0.310 0.000
Z82.2 Family history of deafness and hearing loss
0.690 0.310 0.000
Z82.1 Family history of blindness and visual loss
0.690 0.310 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.690 0.310 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.689 0.311 0.000
B18 Chronic viral hepatitis
0.688 0.312 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.687 0.313 0.000
I25.5 Ischaemic cardiomyopathy
0.687 0.313 0.000
Z22.3 Carrier of other specified bacterial diseases
0.686 0.314 0.000
S80-S89 Injuries to the knee and lower leg
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.684 0.316 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.681 0.319 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.681 0.319 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.681 0.319 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.680 0.320 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.680 0.320 0.000
B65-B83 Helminthiases
0.679 0.321 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.321 0.000
Y10-Y34 Event of undetermined intent
0.679 0.321 0.000
Y00-Y09 Assault
0.679 0.321 0.000
X85-X99 Assault
0.679 0.321 0.000
X50-X57 Overexertion, travel and privation
0.679 0.321 0.000
X30-X39 Exposure to forces of nature
0.679 0.321 0.000
X10-X19 Contact with heat and hot substances
0.679 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.321 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.321 0.000
W75-W84 Other accidental threats to breathing
0.679 0.321 0.000
W65-W74 Accidental drowning and submersion
0.679 0.321 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.321 0.000
V95-V97 Air and space transport accidents
0.679 0.321 0.000
V90-V94 Water transport accidents
0.679 0.321 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.321 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.321 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.321 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.321 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.321 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.321 0.000
O41 Other disorders of amniotic fluid and membranes
0.679 0.321 0.000
O23 Infections of genito-urinary tract in pregnancy
0.679 0.321 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.678 0.322 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
Y43 Primarily systemic agents
0.673 0.327 0.000
I09 Other rheumatic heart diseases
0.673 0.327 0.000
I06 Rheumatic aortic valve diseases
0.673 0.327 0.000
E14.9 Without complications
0.672 0.328 0.000
E50-E64 Other nutritional deficiencies
0.672 0.328 0.000
I05 Rheumatic mitral valve diseases
0.671 0.329 0.000
Y57 Other and unspecified drugs and medicaments
0.670 0.330 0.000
I65.2 Occlusion and stenosis of carotid artery
0.670 0.330 0.000
I22.8 Subsequent myocardial infarction of other sites
0.669 0.331 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.669 0.331 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.667 0.333 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.666 0.334 0.000
I45.2 Bifascicular block
0.665 0.334 0.000
O40 Polyhydramnios
0.664 0.335 0.000
S90-S99 Injuries to the ankle and foot
0.663 0.337 0.000
I50.0 Congestive heart failure
0.663 0.337 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.661 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.661 0.339 0.000
Z82.3 Family history of stroke
0.661 0.339 0.000
Z89 Acquired absence of limb
0.661 0.339 0.000
I24 Other acute ischaemic heart diseases
0.660 0.340 0.000
W29 Contact with other powered hand tools and household machinery
0.660 0.340 0.000
O60-O75 Complications of labour and delivery
0.659 0.341 0.000
O21 Excessive vomiting in pregnancy
0.659 0.341 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.657 0.343 0.000
V10-V19 Pedal cyclist injured in transport accident
0.657 0.343 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
S00-S09 Injuries to the head
0.654 0.346 0.000
I72.4 Aneurysm of artery of lower extremity
0.654 0.346 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.651 0.349 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.651 0.349 0.000
I10-I15 Hypertensive diseases
0.649 0.350 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.649 0.351 0.000
I49.0 Ventricular fibrillation and flutter
0.648 0.351 0.000
I08.9 Multiple valve disease, unspecified
0.646 0.354 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.646 0.354 0.000
A80-A89 Viral infections of the central nervous system
0.646 0.354 0.000
O80 Single spontaneous delivery
0.646 0.354 0.000
I49.9 Cardiac arrhythmia, unspecified
0.645 0.355 0.000
I50.1 Left ventricular failure
0.644 0.356 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.643 0.357 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.643 0.357 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.642 0.358 0.000
I44.6 Other and unspecified fascicular block
0.641 0.359 0.000
I44.5 Left posterior fascicular block
0.641 0.359 0.000
I44.4 Left anterior fascicular block
0.641 0.359 0.000
I45.6 Preexcitation syndrome
0.640 0.360 0.000
A30-A49 Other bacterial diseases
0.640 0.360 0.000
E73.9 Lactose intolerance, unspecified
0.639 0.360 0.000
Z94 Transplanted organ and tissue status
0.638 0.362 0.000
I07 Rheumatic tricuspid valve diseases
0.636 0.364 0.000
O45 Premature separation of placenta [abruptio placentae]
0.636 0.364 0.000
O44 Placenta praevia
0.636 0.364 0.000
O43 Placental disorders
0.636 0.364 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.636 0.364 0.000
O33 Maternal care for known or suspected disproportion
0.636 0.364 0.000
O31 Complications specific to multiple gestation
0.636 0.364 0.000
Z72.0 Tobacco use
0.636 0.364 0.000
S70-S79 Injuries to the hip and thigh
0.634 0.366 0.000
O30 Multiple gestation
0.634 0.366 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.634 0.366 0.000
I30.1 Infective pericarditis
0.634 0.366 0.000
I49.8 Other specified cardiac arrhythmias
0.633 0.366 0.000
B99-B99 Other infectious diseases
0.633 0.366 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.633 0.366 0.000
B50-B64 Protozoal diseases
0.633 0.366 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.633 0.366 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.633 0.366 0.000
A75-A79 Rickettsioses
0.633 0.366 0.000
A70-A74 Other diseases caused by chlamydiae
0.633 0.366 0.000
A65-A69 Other spirochaetal diseases
0.633 0.366 0.000
A20-A28 Certain zoonotic bacterial diseases
0.633 0.366 0.000
A15-A19 Tuberculosis
0.633 0.366 0.000
I49.4 Other and unspecified premature depolarisation
0.632 0.368 0.000
E28 Ovarian dysfunction
0.631 0.369 0.000
I20.0 Unstable angina
0.630 0.370 0.000
S10-S19 Injuries to the neck
0.629 0.371 0.000
W22 Striking against or struck by other objects
0.628 0.372 0.000
O20 Haemorrhage in early pregnancy
0.626 0.374 0.000
O90 Complications of the puerperium, not elsewhere classified
0.625 0.375 0.000
Y42.7 Androgens and anabolic congeners
0.625 0.375 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.623 0.377 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.623 0.377 0.000
X60-X84 Intentional self-harm
0.621 0.379 0.000
Q50-Q56 Congenital malformations of genital organs
0.621 0.379 0.000
I45.8 Other specified conduction disorders
0.621 0.379 0.000
I45.4 Nonspecific intraventricular block
0.621 0.379 0.000
I45.3 Trifascicular block
0.621 0.379 0.000
I45.0 Right fascicular block
0.621 0.379 0.000
Z72.9 Problem related to lifestyle, unspecified
0.620 0.379 0.000
Z72.8 Other problems related to lifestyle
0.620 0.379 0.000
Z72.6 Gambling and betting
0.620 0.379 0.000
Z72.5 High-risk sexual behaviour
0.620 0.379 0.000
Z72.4 Inappropriate diet and eating habits
0.620 0.379 0.000
Z72.3 Lack of physical exercise
0.620 0.379 0.000
I78 Diseases of capillaries
0.620 0.380 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.619 0.380 0.000
I45.1 Other and unspecified right bundle-branch block
0.619 0.381 0.000
I31 Other diseases of pericardium
0.618 0.382 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.617 0.382 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.617 0.382 0.000
E66 Obesity
0.617 0.383 0.000
O00-O08 Pregnancy with abortive outcome
0.616 0.384 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.615 0.385 0.000
O29 Complications of anaesthesia during pregnancy
0.614 0.386 0.000
O28 Abnormal findings on antenatal screening of mother
0.614 0.386 0.000
O22 Venous complications in pregnancy
0.614 0.386 0.000
O25 Malnutrition in pregnancy
0.614 0.386 0.000
E10.2 With renal complications
0.614 0.386 0.000
S80 Superficial injury of lower leg
0.614 0.386 0.000
E10.9 Without complications
0.610 0.390 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.609 0.391 0.000
E10.5 With peripheral circulatory complications
0.607 0.392 0.000
Y40 Systemic antibiotics
0.606 0.394 0.000
Y44 Agents primarily affecting blood constituents
0.605 0.394 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.605 0.395 0.000
E65 Localised adiposity
0.604 0.396 0.000
E10.4 With neurological complications
0.603 0.397 0.000
O47.9 False labour, unspecified
0.603 0.397 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.602 0.398 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.600 0.400 0.000
Z28 Immunisation not carried out
0.599 0.401 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.599 0.401 0.000
Z26 Need for immunisation against other single infectious diseases
0.599 0.401 0.000
Z25 Need for immunisation against other single viral diseases
0.599 0.401 0.000
Z24 Need for immunisation against certain single viral diseases
0.599 0.401 0.000
Z23 Need for immunisation against single bacterial diseases
0.599 0.401 0.000
Z20 Contact with and exposure to communicable diseases
0.599 0.401 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.599 0.401 0.000
B18.2 Chronic viral hepatitis C
0.599 0.401 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.595 0.405 0.000
I45.5 Other specified heart block
0.595 0.405 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.595 0.405 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.593 0.407 0.000
S50-S59 Injuries to the elbow and forearm
0.593 0.407 0.000
Y59 Other and unspecified vaccines and biological substances
0.592 0.408 0.000
Y58 Bacterial vaccines
0.592 0.408 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.592 0.408 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.592 0.408 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.592 0.408 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.592 0.408 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.592 0.408 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.592 0.408 0.000
Y48 Anaesthetics and therapeutic gases
0.592 0.408 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.592 0.408 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.592 0.408 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.592 0.408 0.000
E14.3 With ophthalmic complications
0.591 0.408 0.000
Q66 Congenital deformities of feet
0.591 0.409 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.591 0.409 0.000
Z34 Supervision of normal pregnancy
0.590 0.410 0.000
I73.8 Other specified peripheral vascular diseases
0.589 0.411 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.589 0.411 0.000
E16 Other disorders of pancreatic internal secretion
0.589 0.411 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.589 0.411 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.589 0.411 0.000
O36.4 Maternal care for intra-uterine death
0.589 0.411 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.589 0.411 0.000
O36.2 Maternal care for hydrops foetalis
0.589 0.411 0.000
O36.1 Maternal care for other isoimmunisation
0.589 0.411 0.000
S00 Superficial injury of head
0.588 0.412 0.000
I46 Cardiac arrest
0.587 0.413 0.000
I47 Paroxysmal tachycardia
0.587 0.413 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.587 0.413 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.584 0.416 0.000
I44.0 Atrioventricular block, first degree
0.584 0.416 0.000
X58 Exposure to other specified factors
0.584 0.416 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.583 0.417 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.582 0.418 0.000
E10.1 With ketoacidosis
0.582 0.418 0.000
I77 Other disorders of arteries and arterioles
0.581 0.419 0.000
E14.8 With unspecified complications
0.581 0.419 0.000
E14.7 With multiple complications
0.581 0.419 0.000
E14.6 With other specified complications
0.581 0.419 0.000
E14.5 With peripheral circulatory complications
0.581 0.419 0.000
E14.4 With neurological complications
0.581 0.419 0.000
E14.2 Withrenal complications
0.581 0.419 0.000
E14.1 With ketoacidosis
0.581 0.419 0.000
E14.0 With coma
0.581 0.419 0.000
O80.0 Spontaneous vertex delivery
0.579 0.421 0.000
W25 Contact with sharp glass
0.578 0.422 0.000
W07 Fall involving chair
0.578 0.422 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.578 0.422 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.577 0.423 0.000
Q61 Cystic kidney disease
0.577 0.423 0.000
I99 Other and unspecified disorders of circulatory system
0.576 0.424 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.575 0.425 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.575 0.425 0.000
O47.0 False labour before 37 completed weeks of gestation
0.574 0.426 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.574 0.426 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.574 0.426 0.000
T33-T35 Frostbite
0.573 0.427 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.573 0.427 0.000
T00-T07 Injuries involving multiple body regions
0.573 0.427 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.572 0.427 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.572 0.427 0.000
O81 Single delivery by forceps and vacuum extractor
0.572 0.428 0.000
I72.3 Aneurysm of iliac artery
0.571 0.428 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.571 0.428 0.000
Z90.7 Acquired absence of genital organ(s)
0.571 0.429 0.000
E10.8 With unspecified complications
0.571 0.429 0.000
E10.7 With multiple complications
0.571 0.429 0.000
E10.6 With other specified complications
0.571 0.429 0.000
E10.0 With coma
0.571 0.429 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.571 0.429 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.569 0.431 0.000
W46 Contact with hypodermic needle
0.569 0.431 0.000
W45 Foreign body or object entering through skin
0.569 0.431 0.000
W43 Exposure to vibration
0.569 0.431 0.000
W42 Exposure to noise
0.569 0.431 0.000
W41 Exposure to high-pressure jet
0.569 0.431 0.000
W40 Explosion of other materials
0.569 0.431 0.000
W39 Discharge of firework
0.569 0.431 0.000
W38 Explosion and rupture of other specified pressurised devices
0.569 0.431 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.569 0.431 0.000
W36 Explosion and rupture of gas cylinder
0.569 0.431 0.000
W35 Explosion and rupture of boiler
0.569 0.431 0.000
W34 Discharge from other and unspecified firearms
0.569 0.431 0.000
W33 Rifle, shotgun and larger firearm discharge
0.569 0.431 0.000
W32 Handgun discharge
0.569 0.431 0.000
W31 Contact with other and unspecified machinery
0.569 0.431 0.000
W30 Contact with agricultural machinery
0.569 0.431 0.000
W28 Contact with powered lawn mower
0.569 0.431 0.000
W27 Contact with nonpowered hand tool
0.569 0.431 0.000
W26 Contact with knife, sword or dagger
0.569 0.431 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.569 0.431 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.569 0.431 0.000
W21 Striking against or struck by sports equipment
0.569 0.431 0.000
W20 Struck by thrown, projected or falling object
0.569 0.431 0.000
E67 Other hyperalimentation
0.568 0.431 0.000
E68 Sequelae of hyperalimentation
0.568 0.431 0.000
Z74.0 Reduced mobility
0.568 0.432 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.568 0.432 0.000
U80 Agent resistant to penicillin and related antibiotics
0.567 0.432 0.000
Z83 Family history of other specific disorders
0.566 0.434 0.000
E73.8 Other lactose intolerance
0.566 0.434 0.000
E73.1 Secondary lactase deficiency
0.566 0.434 0.000
E73.0 Congenital lactase deficiency
0.566 0.434 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.566 0.434 0.000
Chapter VIII Diseases of the ear and mastoid process
0.566 0.434 0.000
I95 Hypotension
0.565 0.435 0.000
W29.9 Unspecified place
0.564 0.436 0.000
Z57 Occupational exposure to risk-factors
0.564 0.436 0.000
I30.9 Acute pericarditis, unspecified
0.564 0.436 0.000
I30.8 Other forms of acute pericarditis
0.564 0.436 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.564 0.436 0.000
Z22.5 Carrier of viral hepatitis
0.564 0.436 0.000
I49.2 Junctional premature depolarisation
0.563 0.437 0.000
Y52 Agents primarily affecting the cardiovascular system
0.563 0.437 0.000
S20 Superficial injury of thorax
0.563 0.437 0.000
Z95.2 Presence of prosthetic heart valve
0.562 0.437 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.561 0.439 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.559 0.441 0.000
O36.9 Maternal care for foetal problem, unspecified
0.558 0.442 0.000
Y57.5 X-ray contrast media
0.558 0.442 0.000
I49.1 Atrial premature depolarisation
0.558 0.442 0.000
Z63 Other problems related to primary support group, including family circumstances
0.558 0.442 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.558 0.442 0.000
Chapter X Diseases of the respiratory system
0.556 0.444 0.000
I72.9 Aneurysm of unspecified site
0.555 0.445 0.000
I72.8 Aneurysm of other specified arteries
0.555 0.445 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.555 0.445 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.555 0.445 0.000
I72.2 Aneurysm of renal artery
0.555 0.445 0.000
I72.1 Aneurysm of artery of upper extremity
0.555 0.445 0.000
I72.0 Aneurysm of carotid artery
0.555 0.445 0.000
E29 Testicular dysfunction
0.555 0.445 0.000
E24 Cushing's syndrome
0.555 0.445 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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