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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11746443
log Bayes Factor = 7.30445
Chromosome 5   position 176,798,306  (GRCh37) Explore rs11746443 on Ensembl!
Variant rs11746443 is listed in the   GWAS Catalog   ⇪
Variant rs11746443 is part of Cluster X0025

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N20.0 Calculus of kidney
1.000 0.000 0.000
N20 Calculus of kidney and ureter
1.000 0.000 0.000
N20.1 Calculus of ureter
0.999 0.001 0.000
N20.9 Urinary calculus, unspecified
0.945 0.055 0.000
N20-N23 Urolithiasis
0.895 0.105 0.000
N21 Calculus of lower urinary tract
0.864 0.136 0.000
N21.0 Calculus in bladder
0.843 0.157 0.000
N23 Unspecified renal colic
0.721 0.279 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.642 0.358 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.619 0.381 0.000
N21.8 Other lower urinary tract calculus
0.615 0.385 0.000
N21.1 Calculus in urethra
0.606 0.394 0.000
N20.2 Calculus of kidney with calculus of ureter
0.581 0.419 0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.460 0.540 0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.460 0.540 0.000
H53.9 Visual disturbance, unspecified
0.243 0.757 0.000
H53.8 Other visual disturbances
0.236 0.764 0.000
H53 Visual disturbances
0.228 0.772 0.000
H53.0 Amblyopia ex anopsia
0.176 0.824 0.000
H53.6 Night blindness
0.164 0.836 0.000
H53.5 Colour vision deficiencies
0.164 0.836 0.000
H53.3 Other disorders of binocular vision
0.164 0.836 0.000
H53.4 Visual field defects
0.152 0.848 0.000
H53.1 Subjective visual disturbances
0.127 0.873 0.000
H53-H54 Visual disturbances and blindness
0.092 0.908 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.931 0.069
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.932 0.068
M79.0 Rheumatism, unspecified
0.000 0.934 0.066
H54 Blindness and low vision
0.064 0.936 0.000
H54.9 Unspecified visual impairment (binocular)
0.060 0.940 0.000
M79.08 Rheumatism, unspecified (Other)
0.000 0.949 0.051
H54.7 Unspecified visual loss
0.048 0.952 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.952 0.048
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.953 0.047
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.953 0.047
M79.04 Rheumatism, unspecified (Hand)
0.000 0.953 0.047
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.953 0.047
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.953 0.047
H54.3 Unqualified visual loss, both eyes
0.046 0.954 0.000
H54.1 Blindness, one eye, low vision, other eye
0.046 0.954 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.000 0.955 0.045
H54.6 Unqualified visual loss, one eye
0.043 0.957 0.000
H54.2 Low vision, both eyes
0.042 0.958 0.000
H54.0 Blindness, both eyes
0.039 0.961 0.000
H54.5 Low vision, one eye
0.039 0.961 0.000
H54.4 Blindness, one eye
0.033 0.967 0.000
H53.2 Diplopia
0.030 0.970 0.000
N00-N08 Glomerular diseases
0.024 0.976 0.000
N03 Chronic nephritic syndrome
0.023 0.977 0.000
N03.9 Unspecified
0.022 0.978 0.000
N05 Unspecified nephritic syndrome
0.022 0.978 0.000
N02 Recurrent and persistent haematuria
0.022 0.978 0.000
N05.8 Other
0.020 0.980 0.000
F10.0 Acute intoxication
0.000 0.980 0.020
Chapter XIV Diseases of the genitourinary system
0.020 0.980 0.000
N04 Nephrotic syndrome
0.019 0.981 0.000
N05.9 Unspecified
0.019 0.981 0.000
N00 Acute nephritic syndrome
0.018 0.981 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.018 0.981 0.000
N03.8 Other
0.018 0.982 0.000
N02.8 Other
0.018 0.982 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.018 0.982 0.000
N02.9 Unspecified
0.018 0.982 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.018 0.982 0.000
N06 Isolated proteinuria with specified morphological lesion
0.018 0.982 0.000
N01 Rapidly progressive nephritic syndrome
0.018 0.982 0.000
N02.1 Focal and segmental glomerular lesions
0.017 0.982 0.000
N99-N99 Other disorders of the genitourinary system
0.017 0.983 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.017 0.983 0.000
N03.6 Dense deposit disease
0.017 0.983 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.017 0.983 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.017 0.983 0.000
N03.2 Diffuse membranous glomerulonephritis
0.017 0.983 0.000
N03.1 Focal and segmental glomerular lesions
0.017 0.983 0.000
N03.0 Minor glomerular abnormality
0.017 0.983 0.000
L60.0 Ingrowing nail
0.000 0.983 0.017
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.017 0.983 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.017 0.983 0.000
N10-N16 Renal tubulo-interstitial diseases
0.016 0.984 0.000
N05.6 Dense deposit disease
0.016 0.984 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.016 0.984 0.000
N05.0 Minor glomerular abnormality
0.016 0.984 0.000
N02.7 Diffuse crescentic glomerulonephritis
0.016 0.984 0.000
N02.6 Dense deposit disease
0.016 0.984 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.016 0.984 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.016 0.984 0.000
N02.0 Minor glomerular abnormality
0.016 0.984 0.000
N04.0 Minor glomerular abnormality
0.016 0.984 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.015 0.985 0.000
N05.2 Diffuse membranous glomerulonephritis
0.015 0.985 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.015 0.985 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.015 0.985 0.000
N13 Obstructive and reflux uropathy
0.015 0.985 0.000
N00.9 Unspecified
0.014 0.985 0.000
N05.1 Focal and segmental glomerular lesions
0.014 0.986 0.000
N04.2 Diffuse membranous glomerulonephritis
0.014 0.986 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.014 0.986 0.000
N04.8 Other
0.014 0.986 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.014 0.986 0.000
N04.6 Dense deposit disease
0.014 0.986 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.014 0.986 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.014 0.986 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.014 0.986 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.014 0.986 0.000
N04.1 Focal and segmental glomerular lesions
0.014 0.986 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.014 0.986 0.000
N00.8 Other
0.013 0.986 0.000
N00.7 Diffuse crescentic glomerulonephritis
0.013 0.986 0.000
N00.6 Dense deposit disease
0.013 0.986 0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.013 0.986 0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.013 0.986 0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.013 0.986 0.000
N00.2 Diffuse membranous glomerulonephritis
0.013 0.986 0.000
N00.1 Focal and segmental glomerular lesions
0.013 0.986 0.000
N00.0 Minor glomerular abnormality
0.013 0.986 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.013 0.987 0.000
F17.2 Dependence syndrome
0.000 0.987 0.013
N05.7 Diffuse crescentic glomerulonephritis
0.013 0.987 0.000
N04.9 Unspecified
0.013 0.987 0.000
N02.2 Diffuse membranous glomerulonephritis
0.013 0.987 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.013 0.987 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.013 0.987 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.013 0.987 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.013 0.987 0.000
T39.1 4-Aminophenol derivatives
0.013 0.987 0.000
N01.9 Unspecified
0.013 0.987 0.000
N01.8 Other
0.013 0.987 0.000
N01.7 Diffuse crescentic glomerulonephritis
0.013 0.987 0.000
N01.6 Dense deposit disease
0.013 0.987 0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.013 0.987 0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.013 0.987 0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.013 0.987 0.000
N01.2 Diffuse membranous glomerulonephritis
0.013 0.987 0.000
N01.1 Focal and segmental glomerular lesions
0.013 0.987 0.000
N01.0 Minor glomerular abnormality
0.013 0.987 0.000
N06.9 Unspecified
0.013 0.987 0.000
N06.8 Other
0.013 0.987 0.000
N06.7 Diffuse crescentic glomerulonephritis
0.013 0.987 0.000
N06.6 Dense deposit disease
0.013 0.987 0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.013 0.987 0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.013 0.987 0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.013 0.987 0.000
N06.2 Diffuse membranous glomerulonephritis
0.013 0.987 0.000
N06.1 Focal and segmental glomerular lesions
0.013 0.987 0.000
N06.0 Minor glomerular abnormality
0.013 0.987 0.000
N07.9 Unspecified
0.013 0.987 0.000
N07.8 Other
0.013 0.987 0.000
N07.7 Diffuse crescentic glomerulonephritis
0.013 0.987 0.000
N07.6 Dense deposit disease
0.013 0.987 0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.013 0.987 0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.013 0.987 0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.013 0.987 0.000
N07.2 Diffuse membranous glomerulonephritis
0.013 0.987 0.000
N07.1 Focal and segmental glomerular lesions
0.013 0.987 0.000
N07.0 Minor glomerular abnormality
0.013 0.987 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.013 0.987 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.013 0.987 0.000
N13.3 Other and unspecified hydronephrosis
0.013 0.987 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.012 0.987 0.000
H73.8 Other specified disorders of tympanic membrane
0.000 0.988 0.012
N13.8 Other obstructive and reflux uropathy
0.012 0.988 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.012 0.988 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.988 0.012
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.012 0.988 0.000
F10.2 Dependence syndrome
0.000 0.988 0.012
N99.5 Malfunction of external stoma of urinary tract
0.012 0.988 0.000
N99.0 Postprocedural renal failure
0.012 0.988 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.011 0.988 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.011 0.989 0.000
N15 Other renal tubulo-interstitial diseases
0.011 0.989 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.011 0.989 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.011 0.989 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.010 0.990 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.010 0.990 0.000
T39.0 Salicylates
0.010 0.990 0.000
N99.1 Postprocedural urethral stricture
0.010 0.990 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.010 0.990 0.000
D32.0 Cerebral meninges
0.010 0.990 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.990 0.010
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.000 0.990 0.010
N13.6 Pyonephrosis
0.010 0.990 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.010 0.990 0.000
T43.6 Psychostimulants with abuse potential
0.010 0.990 0.000
N25-N29 Other disorders of kidney and ureter
0.010 0.990 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.009 0.991 0.000
F10.5 Psychotic disorder
0.000 0.991 0.009
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.009 0.991 0.000
H73 Other disorders of tympanic membrane
0.000 0.991 0.009
N11 Chronic tubulo-interstitial nephritis
0.009 0.991 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.009 0.991 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.009 0.991 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.009 0.991 0.000
T39.4 Antirheumatics, not elsewhere classified
0.009 0.991 0.000
T39.2 Pyrazolone derivatives
0.009 0.991 0.000
F10.8 Other mental and behavioural disorders
0.000 0.991 0.009
F10.7 Residual and late-onset psychotic disorder
0.000 0.991 0.009
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere
0.009 0.991 0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection
0.009 0.991 0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders
0.009 0.991 0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases
0.009 0.991 0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
0.009 0.991 0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases
0.009 0.991 0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere
0.009 0.991 0.000
N17-N19 Renal failure
0.009 0.991 0.000
N15.1 Renal and perinephric abscess
0.008 0.991 0.000
N14.4 Toxic nephropathy, not elsewhere classified
0.008 0.991 0.000
N14.3 Nephropathy induced by heavy metals
0.008 0.991 0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance
0.008 0.991 0.000
N14.0 Analgesic nephropathy
0.008 0.991 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.991 0.009
C90.0 Multiple myeloma
0.009 0.991 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.008 0.992 0.000
N15.8 Other specified renal tubulo-interstitial diseases
0.008 0.992 0.000
N15.0 Balkan nephropathy
0.008 0.992 0.000
L60 Nail disorders
0.000 0.992 0.008
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.008 0.992 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.000 0.992 0.008
T43.9 Psychotropic drug, unspecified
0.008 0.992 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.008 0.992 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.008 0.992 0.000
H71 Cholesteatoma of middle ear
0.000 0.992 0.008
F10.4 Withdrawal state with delirium
0.000 0.992 0.008
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.992 0.008
N18.4 Chronic kidney disease, stage 4
0.008 0.992 0.000
N99.2 Postprocedural adhesions of vagina
0.008 0.992 0.000
F10.9 Unspecified mental and behavioural disorder
0.000 0.992 0.008
F10.6 Amnesic syndrome
0.000 0.992 0.007
N26 Unspecified contracted kidney
0.008 0.992 0.000
N10 Acute tubulo-interstitial nephritis
0.008 0.992 0.000
F17.9 Unspecified mental and behavioural disorder
0.000 0.993 0.007
F17.8 Other mental and behavioural disorders
0.000 0.993 0.007
F17.7 Residual and late-onset psychotic disorder
0.000 0.993 0.007
F17.6 Amnesic syndrome
0.000 0.993 0.007
F17.5 Psychotic disorder
0.000 0.993 0.007
F17.4 Withdrawal state with delirium
0.000 0.993 0.007
F17.3 Withdrawal state
0.000 0.993 0.007
F17.0 Acute intoxication
0.000 0.993 0.007
T36-T50 Poisoning by drugs, medicaments and biological substances
0.007 0.993 0.000
N18 Chronic renal failure
0.007 0.993 0.000
L60.3 Nail dystrophy
0.000 0.993 0.007
N27 Small kidney of unknown cause
0.007 0.993 0.000
N13.4 Hydroureter
0.007 0.993 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.007 0.993 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.993 0.007
H73.0 Acute myringitis
0.000 0.993 0.007
N11.8 Other chronic tubulo-interstitial nephritis
0.007 0.993 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.007 0.993 0.000
F10.3 Withdrawal state
0.000 0.993 0.007
N15.9 Renal tubulo-interstitial disease, unspecified
0.006 0.993 0.000
N25 Disorders resulting from impaired renal tubular function
0.007 0.993 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.007 0.993 0.000
L60.2 Onychogryphosis
0.000 0.993 0.007
N18.1 Chronic kidney disease, stage 1
0.006 0.994 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.994 0.006
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.994 0.006
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.994 0.006
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.994 0.006
H73.1 Chronic myringitis
0.000 0.994 0.006
L60.5 Yellow nail syndrome
0.000 0.994 0.006
L60.4 Beau's lines
0.000 0.994 0.006
L60.1 Onycholysis
0.000 0.994 0.006
N18.3 Chronic kidney disease, stage 3
0.006 0.994 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.994 0.006
H65-H75 Diseases of middle ear and mastoid
0.000 0.994 0.006
F10.1 Harmful use
0.000 0.994 0.006
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.006 0.994 0.000
F17.1 Harmful use
0.000 0.994 0.006
N18.9 Chronic renal failure, unspecified
0.006 0.994 0.000
Y42.5 Other oestrogens and progestogens
0.006 0.994 0.000
H66.3 Other chronic suppurative otitis media
0.000 0.994 0.006
N27.0 Small kidney, unilateral
0.006 0.994 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.006 0.994 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.006 0.994 0.000
N11.1 Chronic obstructive pyelonephritis
0.005 0.994 0.000
F19.1 Harmful use
0.000 0.994 0.005
F19.2 Dependence syndrome
0.000 0.994 0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.006 0.994 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.005 0.994 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.005 0.994 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.005 0.994 0.000
N27.9 Small kidney, unspecified
0.005 0.994 0.000
W19.2 School, other institution and public administrative area
0.000 0.994 0.006
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.005 0.995 0.000
H93.1 Tinnitus
0.000 0.995 0.005
H66 Suppurative and unspecified otitis media
0.000 0.995 0.005
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.005 0.995 0.000
R10.2 Pelvic and perineal pain
0.005 0.995 0.000
C90.2 Plasmacytoma, extramedullary
0.005 0.995 0.000
F19.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F19.8 Other mental and behavioural disorders
0.000 0.995 0.005
F19.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F19.6 Amnesic syndrome
0.000 0.995 0.005
F19.5 Psychotic disorder
0.000 0.995 0.005
F19.4 Withdrawal state with delirium
0.000 0.995 0.005
F19.3 Withdrawal state
0.000 0.995 0.005
F19.0 Acute intoxication
0.000 0.995 0.005
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
N29.0 Late syphilis of kidney
0.005 0.995 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.005 0.995 0.000
N25.1 Nephrogenic diabetes insipidus
0.005 0.995 0.000
L60.9 Nail disorder, unspecified
0.000 0.995 0.005
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.005 0.995 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.005 0.995 0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified
0.005 0.995 0.000
N25.0 Renal osteodystrophy
0.005 0.995 0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere
0.005 0.995 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.005 0.995 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.005 0.995 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.005 0.995 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.005 0.995 0.000
T44.0 Anticholinesterase agents
0.005 0.995 0.000
T40.4 Other synthetic narcotics
0.005 0.995 0.000
H69 Other disorders of Eustachian tube
0.000 0.995 0.005
N27.1 Small kidney, bilateral
0.005 0.995 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.005 0.995 0.000
C90.3 Solitary plasmacytoma
0.005 0.995 0.000
F14.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F14.8 Other mental and behavioural disorders
0.000 0.995 0.005
F14.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F14.6 Amnesic syndrome
0.000 0.995 0.005
F14.5 Psychotic disorder
0.000 0.995 0.005
F14.4 Withdrawal state with delirium
0.000 0.995 0.005
F14.3 Withdrawal state
0.000 0.995 0.005
F14.2 Dependence syndrome
0.000 0.995 0.005
F14.1 Harmful use
0.000 0.995 0.005
F14.0 Acute intoxication
0.000 0.995 0.005
F16.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F16.8 Other mental and behavioural disorders
0.000 0.995 0.005
F16.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F16.6 Amnesic syndrome
0.000 0.995 0.005
F16.5 Psychotic disorder
0.000 0.995 0.005
F16.4 Withdrawal state with delirium
0.000 0.995 0.005
F16.3 Withdrawal state
0.000 0.995 0.005
F16.2 Dependence syndrome
0.000 0.995 0.005
F16.1 Harmful use
0.000 0.995 0.005
F16.0 Acute intoxication
0.000 0.995 0.005
F18.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F18.8 Other mental and behavioural disorders
0.000 0.995 0.005
F18.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F18.6 Amnesic syndrome
0.000 0.995 0.005
F18.5 Psychotic disorder
0.000 0.995 0.005
F18.4 Withdrawal state with delirium
0.000 0.995 0.005
F18.3 Withdrawal state
0.000 0.995 0.005
F18.2 Dependence syndrome
0.000 0.995 0.005
F18.1 Harmful use
0.000 0.995 0.005
F18.0 Acute intoxication
0.000 0.995 0.005
T36 Poisoning by systemic antibiotics
0.005 0.995 0.000
F15.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F15.8 Other mental and behavioural disorders
0.000 0.995 0.005
F15.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F15.6 Amnesic syndrome
0.000 0.995 0.005
F15.5 Psychotic disorder
0.000 0.995 0.005
F15.4 Withdrawal state with delirium
0.000 0.995 0.005
F15.3 Withdrawal state
0.000 0.995 0.005
F15.2 Dependence syndrome
0.000 0.995 0.005
F15.0 Acute intoxication
0.000 0.995 0.005
F11 Mental and behavioural disorders due to use of opioids
0.000 0.995 0.005
N99.3 Prolapse of vaginal vault after hysterectomy
0.005 0.995 0.000
T47.2 Stimulant laxatives
0.005 0.995 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.005 0.995 0.000
F15.1 Harmful use
0.000 0.995 0.005
F13.2 Dependence syndrome
0.000 0.995 0.004
F13.9 Unspecified mental and behavioural disorder
0.000 0.995 0.004
F13.8 Other mental and behavioural disorders
0.000 0.995 0.004
F13.7 Residual and late-onset psychotic disorder
0.000 0.995 0.004
F13.6 Amnesic syndrome
0.000 0.995 0.004
F13.5 Psychotic disorder
0.000 0.995 0.004
F13.4 Withdrawal state with delirium
0.000 0.995 0.004
F13.1 Harmful use
0.000 0.995 0.004
F13.0 Acute intoxication
0.000 0.995 0.004
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.995 0.005
H68 Eustachian salpingitis and obstruction
0.000 0.995 0.005
H67 Otitis media in diseases classified elsewhere
0.000 0.995 0.005
H47.1 Papilloedema, unspecified
0.005 0.995 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.004 0.995 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.004 0.995 0.000
T47.7 Emetics
0.004 0.995 0.000
T47.6 Antidiarrhoeal drugs
0.004 0.995 0.000
T47.5 Digestants
0.004 0.995 0.000
T47.4 Other laxatives
0.004 0.995 0.000
T47.3 Saline and osmotic laxatives
0.004 0.995 0.000
T47.0 Histamine H(2)-receptor antagonists
0.004 0.995 0.000
D32 Benign neoplasm of meninges
0.005 0.995 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.001 0.995 0.004
I27.2 Other secondary pulmonary hypertension
0.005 0.995 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.004 0.996 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.004 0.996 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.996 0.004
N18.8 Other chronic renal failure
0.004 0.996 0.000
I07.1 Tricuspid insufficiency
0.004 0.996 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.004 0.996 0.000
L60.8 Other nail disorders
0.000 0.996 0.004
N25.8 Other disorders resulting from impaired renal tubular function
0.004 0.996 0.000
N82.3 Fistula of vagina to large intestine
0.000 0.996 0.004
F13.3 Withdrawal state
0.000 0.996 0.004
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.004 0.996 0.000
T41.5 Therapeutic gases
0.004 0.996 0.000
T41.4 Anaesthetic, unspecified
0.004 0.996 0.000
T41.3 Local anaesthetics
0.004 0.996 0.000
T41.2 Other and unspecified general anaesthetics
0.004 0.996 0.000
T41.1 Intravenous anaesthetics
0.004 0.996 0.000
T41.0 Inhaled anaesthetics
0.004 0.996 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.004 0.996 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.004 0.996 0.000
T48.5 Anti-common-cold drugs
0.004 0.996 0.000
T48.4 Expectorants
0.004 0.996 0.000
T48.3 Antitussives
0.004 0.996 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.004 0.996 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.004 0.996 0.000
T48.0 Oxytocic drugs
0.004 0.996 0.000
T49.9 Topical agent, unspecified
0.004 0.996 0.000
T49.8 Other topical agents
0.004 0.996 0.000
T49.7 Dental drugs, topically applied
0.004 0.996 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.004 0.996 0.000
T49.5 Ophthalmological drugs and preparations
0.004 0.996 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.004 0.996 0.000
T49.3 Emollients, demulcents and protectants
0.004 0.996 0.000
T49.2 Local astringents and local detergents
0.004 0.996 0.000
T49.1 Antipruritics
0.004 0.996 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.004 0.996 0.000
H69.8 Other specified disorders of Eustachian tube
0.000 0.996 0.004
H66.0 Acute suppurative otitis media
0.000 0.996 0.004
J45.9 Asthma, unspecified
0.004 0.996 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.004 0.996 0.000
C90.1 Plasma cell leukaemia
0.004 0.996 0.000
N18.0 End-stage renal disease
0.004 0.996 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.004 0.996 0.000
T37.5 Antiviral drugs
0.004 0.996 0.000
T37.4 Anthelminthics
0.004 0.996 0.000
T37.3 Other antiprotozoal drugs
0.004 0.996 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.004 0.996 0.000
T37.1 Antimycobacterial drugs
0.004 0.996 0.000
T37.0 Sulphonamides
0.004 0.996 0.000
H70 Mastoiditis and related conditions
0.000 0.996 0.004
D32.9 Meninges, unspecified
0.004 0.996 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.004 0.996 0.000
T40.8 Lysergide [LSD]
0.004 0.996 0.000
T40.7 Cannabis (derivatives)
0.004 0.996 0.000
T40.5 Cocaine
0.004 0.996 0.000
T40.3 Methadone
0.004 0.996 0.000
T40.1 Heroin
0.004 0.996 0.000
T40.0 Opium
0.004 0.996 0.000
H69.9 Eustachian tube disorder, unspecified
0.000 0.996 0.004
I97.1 Other functional disturbances following cardiac surgery
0.004 0.996 0.000
N17 Acute renal failure
0.004 0.996 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.996 0.004
H69.0 Patulous Eustachian tube
0.000 0.996 0.004
T38.9 Other and unspecified hormone antagonists
0.004 0.996 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.004 0.996 0.000
T38.7 Androgens and anabolic congeners
0.004 0.996 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.004 0.996 0.000
T38.5 Other oestrogens and progestogens
0.004 0.996 0.000
T38.4 Oral contraceptives
0.004 0.996 0.000
T38.2 Antithyroid drugs
0.004 0.996 0.000
T38.0 Glucocorticoids and synthetic analogues
0.004 0.996 0.000
H74.4 Polyp of middle ear
0.000 0.996 0.004
T36.9 Systemic antibiotic, unspecified
0.003 0.996 0.000
T36.8 Other systemic antibiotics
0.003 0.996 0.000
T36.7 Antifungal antibiotics, systemically used
0.003 0.996 0.000
T36.6 Rifamycins
0.003 0.996 0.000
T36.5 Aminoglycosides
0.003 0.996 0.000
T36.4 Tetracyclines
0.003 0.996 0.000
T36.3 Macrolides
0.003 0.996 0.000
T36.2 Chloramphenicol group
0.003 0.996 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.003 0.996 0.000
F11.9 Unspecified mental and behavioural disorder
0.000 0.996 0.003
F11.8 Other mental and behavioural disorders
0.000 0.996 0.003
F11.7 Residual and late-onset psychotic disorder
0.000 0.996 0.003
F11.6 Amnesic syndrome
0.000 0.996 0.003
F11.5 Psychotic disorder
0.000 0.996 0.003
F11.4 Withdrawal state with delirium
0.000 0.996 0.003
F11.0 Acute intoxication
0.000 0.996 0.003
T37.8 Other specified systemic anti-infectives and antiparasitics
0.003 0.996 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.000 0.996 0.004
T50.6 Antidotes and chelating agents, not elsewhere classified
0.004 0.996 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.004 0.996 0.000
I27 Other pulmonary heart diseases
0.004 0.996 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.004 0.996 0.000
H66.4 Suppurative otitis media, unspecified
0.000 0.996 0.003
I08.1 Disorders of both mitral and tricuspid valves
0.004 0.996 0.000
C71.9 Brain, unspecified
0.000 0.996 0.004
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.996 0.003
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.996 0.003
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.996 0.003
H68.1 Obstruction of Eustachian tube
0.000 0.996 0.003
H68.0 Eustachian salpingitis
0.000 0.996 0.003
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.996 0.003
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.003 0.996 0.000
H74 Other disorders of middle ear and mastoid
0.000 0.996 0.003
F12.9 Unspecified mental and behavioural disorder
0.001 0.996 0.003
F12.8 Other mental and behavioural disorders
0.001 0.996 0.003
F12.7 Residual and late-onset psychotic disorder
0.001 0.996 0.003
F12.6 Amnesic syndrome
0.001 0.996 0.003
F12.5 Psychotic disorder
0.001 0.996 0.003
F12.4 Withdrawal state with delirium
0.001 0.996 0.003
F12.3 Withdrawal state
0.001 0.996 0.003
F12.0 Acute intoxication
0.001 0.996 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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