TreeWAS – Variant ID: rs11748327

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I73.0 Raynaud's syndrome	0.712	0.288	0.000
C78.7 Secondary malignant neoplasm of liver	0.259	0.741	0.000
C78.0 Secondary malignant neoplasm of lung	0.259	0.741	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.258	0.742	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.243	0.757	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.223	0.777	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.210	0.790	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.177	0.823	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.164	0.836	0.000
C78.2 Secondary malignant neoplasm of pleura	0.129	0.871	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.128	0.872	0.000
I73 Other peripheral vascular diseases	0.113	0.887	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.076	0.923	0.000
I73.8 Other specified peripheral vascular diseases	0.073	0.927	0.000
T43.2 Other and unspecified antidepressants	0.026	0.974	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.024	0.976	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.021	0.979	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.020	0.980	0.000
T43.6 Psychostimulants with abuse potential	0.020	0.980	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.020	0.980	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.020	0.980	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.020	0.980	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
I78 Diseases of capillaries	0.019	0.981	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.019	0.981	0.000
I78.1 Naevus, nonneoplastic	0.018	0.982	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.017	0.983	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.017	0.983	0.000
T43.9 Psychotropic drug, unspecified	0.017	0.983	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.017	0.983	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.017	0.983	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.017	0.983	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.017	0.983	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.016	0.983	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.017	0.983	0.000
T36 Poisoning by systemic antibiotics	0.016	0.984	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.984	0.016
C76 Malignant neoplasm of other and ill-defined sites	0.016	0.984	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.016	0.984	0.000
T42.4 Benzodiazepines	0.016	0.984	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.016	0.984	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.015	0.984	0.000
T47.2 Stimulant laxatives	0.015	0.984	0.000
T47.4 Other laxatives	0.015	0.985	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.015	0.985	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.015	0.985	0.000
I78.9 Disease of capillaries, unspecified	0.015	0.985	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.015	0.985	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.015	0.985	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.015	0.985	0.000
T47.7 Emetics	0.015	0.985	0.000
T47.6 Antidiarrhoeal drugs	0.015	0.985	0.000
T47.5 Digestants	0.015	0.985	0.000
T47.3 Saline and osmotic laxatives	0.015	0.985	0.000
T47.0 Histamine H(2)-receptor antagonists	0.015	0.985	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.015	0.985	0.000
I72 Other aneurysm	0.014	0.986	0.000
T39.0 Salicylates	0.014	0.986	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.014	0.986	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.014	0.986	0.000
C76.0 Head, face and neck	0.014	0.986	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.014	0.986	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.014	0.986	0.000
T39.4 Antirheumatics, not elsewhere classified	0.014	0.986	0.000
T39.2 Pyrazolone derivatives	0.014	0.986	0.000
I77 Other disorders of arteries and arterioles	0.014	0.986	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.014	0.986	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.014	0.986	0.000
C76.2 Abdomen	0.014	0.986	0.000
I71 Aortic aneurysm and dissection	0.014	0.986	0.000
T42.0 Hydantoin derivatives	0.013	0.987	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.013	0.987	0.000
T45.0 Antiallergic and antiemetic drugs	0.013	0.987	0.000
T50.4 Drugs affecting uric acid metabolism	0.013	0.987	0.000
T36.0 Penicillins	0.013	0.987	0.000
I72.4 Aneurysm of artery of lower extremity	0.013	0.987	0.000
T36.3 Macrolides	0.013	0.987	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.013	0.987	0.000
T42.3 Barbiturates	0.013	0.987	0.000
T42.2 Succinimides and oxazolidinediones	0.013	0.987	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.013	0.987	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.012	0.987	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.012	0.987	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.012	0.988	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.012	0.988	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.012	0.988	0.000
T49.9 Topical agent, unspecified	0.012	0.988	0.000
T49.8 Other topical agents	0.012	0.988	0.000
T49.7 Dental drugs, topically applied	0.012	0.988	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.012	0.988	0.000
T49.5 Ophthalmological drugs and preparations	0.012	0.988	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.012	0.988	0.000
T49.3 Emollients, demulcents and protectants	0.012	0.988	0.000
T49.2 Local astringents and local detergents	0.012	0.988	0.000
T49.1 Antipruritics	0.012	0.988	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.012	0.988	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.012	0.988	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.012	0.988	0.000
T44.0 Anticholinesterase agents	0.012	0.988	0.000
T36.9 Systemic antibiotic, unspecified	0.012	0.988	0.000
T36.8 Other systemic antibiotics	0.012	0.988	0.000
T36.7 Antifungal antibiotics, systemically used	0.012	0.988	0.000
T36.6 Rifamycins	0.012	0.988	0.000
T36.5 Aminoglycosides	0.012	0.988	0.000
T36.4 Tetracyclines	0.012	0.988	0.000
T36.2 Chloramphenicol group	0.012	0.988	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.012	0.988	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.012	0.988	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.012	0.988	0.000
C76.7 Other ill-defined sites	0.012	0.988	0.000
C76.5 Lower limb	0.012	0.988	0.000
C76.4 Upper limb	0.012	0.988	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.989	0.000
T50.5 Appetite depressants	0.011	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.011	0.989	0.000
I72.9 Aneurysm of unspecified site	0.011	0.989	0.000
C76.1 Thorax	0.011	0.989	0.000
I77.6 Arteritis, unspecified	0.011	0.989	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.011	0.989	0.000
I73.9 Peripheral vascular disease, unspecified	0.011	0.989	0.000
I72.1 Aneurysm of artery of upper extremity	0.011	0.989	0.000
J84 Other interstitial pulmonary diseases	0.000	0.989	0.011
T41.5 Therapeutic gases	0.011	0.989	0.000
T41.4 Anaesthetic, unspecified	0.011	0.989	0.000
T41.3 Local anaesthetics	0.011	0.989	0.000
T41.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
T41.1 Intravenous anaesthetics	0.011	0.989	0.000
T41.0 Inhaled anaesthetics	0.011	0.989	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.989	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.011	0.989	0.000
T48.5 Anti-common-cold drugs	0.011	0.989	0.000
T48.4 Expectorants	0.011	0.989	0.000
T48.3 Antitussives	0.011	0.989	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.989	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.989	0.000
T48.0 Oxytocic drugs	0.011	0.989	0.000
I72.2 Aneurysm of renal artery	0.011	0.989	0.000
I77.2 Rupture of artery	0.011	0.989	0.000
I77.8 Other specified disorders of arteries and arterioles	0.011	0.989	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
T37.5 Antiviral drugs	0.011	0.989	0.000
T37.4 Anthelminthics	0.011	0.989	0.000
T37.3 Other antiprotozoal drugs	0.011	0.989	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.989	0.000
T37.1 Antimycobacterial drugs	0.011	0.989	0.000
T37.0 Sulphonamides	0.011	0.989	0.000
I78.8 Other diseases of capillaries	0.011	0.989	0.000
I70 Atherosclerosis	0.011	0.989	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.011	0.989	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.010	0.989	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.010	0.989	0.000
I77.3 Arterial fibromuscular dysplasia	0.010	0.989	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.010	0.989	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.010	0.989	0.000
T45.8 Other primarily systemic and haematological agents	0.010	0.989	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.010	0.989	0.000
T45.6 Fibrinolysis-affecting drugs	0.010	0.989	0.000
T45.4 Iron and its compounds	0.010	0.989	0.000
T45.3 Enzymes, not elsewhere classified	0.010	0.989	0.000
M62.8 Other specified disorders of muscle	0.010	0.990	0.000
I77.1 Stricture of artery	0.010	0.990	0.000
K51.4 Pseudopolyposis of colon	0.010	0.990	0.000
T45.2 Vitamins, not elsewhere classified	0.010	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.010	0.990	0.000
I77.5 Necrosis of artery	0.010	0.990	0.000
I77.4 Coeliac artery compression syndrome	0.010	0.990	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.010	0.990	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.010	0.990	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.010	0.990	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.010	0.990	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.010	0.990	0.000
T50.8 Diagnostic agents	0.010	0.990	0.000
C76.3 Pelvis	0.010	0.990	0.000
I72.0 Aneurysm of carotid artery	0.010	0.990	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.990	0.010
T38.9 Other and unspecified hormone antagonists	0.009	0.990	0.000
T38.7 Androgens and anabolic congeners	0.009	0.990	0.000
T38.5 Other oestrogens and progestogens	0.009	0.990	0.000
T38.4 Oral contraceptives	0.009	0.990	0.000
T38.2 Antithyroid drugs	0.009	0.990	0.000
T38.0 Glucocorticoids and synthetic analogues	0.009	0.990	0.000
T42.1 Iminostilbenes	0.009	0.990	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.009	0.991	0.000
C80 Malignant neoplasm without specification of site	0.009	0.991	0.000
I79.1 Aortitis in diseases classified elsewhere	0.009	0.991	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.009	0.991	0.000
M62.88 Other specified disorders of muscle (Other)	0.009	0.991	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.009	0.991	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.009	0.991	0.000
T46.7 Peripheral vasodilators	0.009	0.991	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.991	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.009	0.991	0.000
T46.1 Calcium-channel blockers	0.009	0.991	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.991	0.009
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.009	0.991	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.009	0.991	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.008	0.991	0.000
I70.1 Atherosclerosis of renal artery	0.008	0.992	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.992	0.008
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.008	0.992	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.008	0.992	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.008	0.992	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.008	0.992	0.000
D52.9 Folate deficiency anaemia, unspecified	0.008	0.992	0.000
I70.9 Generalised and unspecified atherosclerosis	0.008	0.992	0.000
I72.8 Aneurysm of other specified arteries	0.008	0.992	0.000
M62.84 Other specified disorders of muscle (Hand)	0.008	0.992	0.000
M62 Other disorders of muscle	0.008	0.992	0.000
I74 Arterial embolism and thrombosis	0.008	0.992	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.008	0.992	0.000
T45.5 Anticoagulants	0.007	0.992	0.000
I70.8 Atherosclerosis of other arteries	0.007	0.992	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.992	0.008
I85.9 Oesophageal varices without bleeding	0.000	0.992	0.008
T39.1 4-Aminophenol derivatives	0.007	0.993	0.000
I72.3 Aneurysm of iliac artery	0.007	0.993	0.000
R68.8 Other specified general symptoms and signs	0.007	0.993	0.000
M62.0 Diastasis of muscle	0.007	0.993	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
C80.9 Malignant neoplasm, unspecified	0.007	0.993	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.007	0.993	0.000
N32.3 Diverticulum of bladder	0.000	0.993	0.007
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.006	0.993	0.000
M62.08 Diastasis of muscle (Other)	0.007	0.993	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.006	0.993	0.000
S31.4 Open wound of vagina and vulva	0.007	0.993	0.000
I74.5 Embolism and thrombosis of iliac artery	0.006	0.994	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.006	0.994	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.006	0.994	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.994	0.006
J45.0 Predominantly allergic asthma	0.006	0.994	0.000
S31 Open wound of abdomen, lower back and pelvis	0.006	0.994	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.006	0.994	0.000
M62.6 Muscle strain	0.006	0.994	0.000
I71.0 Dissection of aorta [any part]	0.006	0.994	0.000
I77.0 Arteriovenous fistula, acquired	0.006	0.994	0.000
Z48.8 Other specified surgical follow-up care	0.006	0.994	0.000
I70.0 Atherosclerosis of aorta	0.006	0.994	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.006	0.994	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.006	0.994	0.000
M62.9 Disorder of muscle, unspecified	0.006	0.994	0.000
M62.4 Contracture of muscle	0.006	0.994	0.000
M62.3 Immobility syndrome (paraplegic)	0.006	0.994	0.000
M62.2 Ischaemic infarction of muscle	0.006	0.994	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.006	0.994	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.005	0.994	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.006	0.994	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.005	0.994	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.005	0.995	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.005	0.995	0.000
M62.06 Diastasis of muscle (Lower leg)	0.005	0.995	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.005	0.995	0.000
M62.04 Diastasis of muscle (Hand)	0.005	0.995	0.000
M62.03 Diastasis of muscle (Forearm)	0.005	0.995	0.000
M62.02 Diastasis of muscle (Upper arm)	0.005	0.995	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.005	0.995	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.005	0.995	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.005	0.995	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
F45.8 Other somatoform disorders	0.000	0.995	0.005
H34.8 Other retinal vascular occlusions	0.005	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.005	0.995	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.005	0.995	0.000
H34.1 Central retinal artery occlusion	0.005	0.995	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.005	0.995	0.000
S31.2 Open wound of penis	0.005	0.995	0.000
S36 Injury of intra-abdominal organs	0.005	0.995	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.005	0.995	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.005	0.995	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.005	0.995	0.000
S32 Fracture of lumbar spine and pelvis	0.005	0.995	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.005	0.995	0.000
S32.40 Fracture of acetabulum (closed)	0.005	0.995	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.005	0.995	0.000
M62.66 Muscle strain (Lower leg)	0.005	0.995	0.000
S30.1 Contusion of abdominal wall	0.005	0.995	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.005	0.995	0.000
S32.4 Fracture of acetabulum	0.005	0.995	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.005	0.995	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.005	0.995	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.005	0.995	0.000
M62.69 Muscle strain (Site unspecified)	0.004	0.995	0.000
M62.68 Muscle strain (Other)	0.004	0.995	0.000
M62.67 Muscle strain (Ankle and foot)	0.004	0.995	0.000
M62.64 Muscle strain (Hand)	0.004	0.995	0.000
M62.63 Muscle strain (Forearm)	0.004	0.995	0.000
M62.62 Muscle strain (Upper arm)	0.004	0.995	0.000
M62.61 Muscle strain (Shoulder region)	0.004	0.995	0.000
M62.60 Muscle strain (Multiple sites)	0.004	0.995	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.005	0.995	0.000
S31.5 Open wound of other and unspecified external genital organs	0.005	0.995	0.000
S31.3 Open wound of scrotum and testes	0.005	0.995	0.000
S31.1 Open wound of abdominal wall	0.005	0.995	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.004	0.995	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.995	0.000
T40.8 Lysergide [LSD]	0.004	0.995	0.000
T40.7 Cannabis (derivatives)	0.004	0.995	0.000
T40.3 Methadone	0.004	0.995	0.000
T40.1 Heroin	0.004	0.995	0.000
T40.0 Opium	0.004	0.995	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.004	0.995	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.004	0.995	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.004	0.995	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.004	0.995	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.004	0.995	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.004	0.995	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.004	0.995	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.004	0.995	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.004	0.995	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.004	0.995	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.004	0.995	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.004	0.995	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.004	0.995	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.004	0.995	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.004	0.995	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.004	0.995	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.004	0.995	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.004	0.995	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.004	0.995	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.004	0.995	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.004	0.995	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.004	0.995	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.004	0.995	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.004	0.995	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.004	0.995	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.004	0.995	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.004	0.995	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.004	0.995	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.004	0.995	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.004	0.995	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.004	0.995	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.004	0.995	0.000
M62.49 Contracture of muscle (Site unspecified)	0.004	0.995	0.000
M62.48 Contracture of muscle (Other)	0.004	0.995	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.004	0.995	0.000
M62.46 Contracture of muscle (Lower leg)	0.004	0.995	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.004	0.995	0.000
M62.44 Contracture of muscle (Hand)	0.004	0.995	0.000
M62.43 Contracture of muscle (Forearm)	0.004	0.995	0.000
M62.42 Contracture of muscle (Upper arm)	0.004	0.995	0.000
M62.41 Contracture of muscle (Shoulder region)	0.004	0.995	0.000
M62.40 Contracture of muscle (Multiple sites)	0.004	0.995	0.000
N42.8 Other specified disorders of prostate	0.000	0.995	0.005
I85 Oesophageal varices	0.000	0.996	0.004
S64 Injury of nerves at wrist and hand level	0.000	0.996	0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.004	0.996	0.000
S35.2 Injury of coeliac or mesenteric artery	0.004	0.996	0.000
S37 Injury of urinary and pelvic organs	0.004	0.996	0.000
T40.5 Cocaine	0.004	0.996	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
H34 Retinal vascular occlusions	0.004	0.996	0.000
S36.1 Injury of liver or gallbladder	0.004	0.996	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.996	0.004
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.004	0.996	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.004	0.996	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.004	0.996	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.004	0.996	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.004	0.996	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.004	0.996	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.004	0.996	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.004	0.996	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.004	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.996	0.004
N41.1 Chronic prostatitis	0.004	0.996	0.000
S36.0 Injury of spleen	0.004	0.996	0.000
S92.0 Fracture of calcaneus	0.000	0.996	0.004
S64.4 Injury of digital nerve of other finger	0.000	0.996	0.004
S36.8 Injury of other intra-abdominal organs	0.004	0.996	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
H49 Paralytic strabismus	0.004	0.996	0.000
F41.2 Mixed anxiety and depressive disorder	0.004	0.996	0.000
S31.0 Open wound of lower back and pelvis	0.004	0.996	0.000
S32.5 Fracture of pubis	0.004	0.996	0.000
H49.2 Sixth [abducent] nerve palsy	0.004	0.996	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.004	0.996	0.000
S36.7 Injury of multiple intra-abdominal organs	0.004	0.996	0.000
S36.6 Injury of rectum	0.004	0.996	0.000
S36.5 Injury of colon	0.004	0.996	0.000
S36.4 Injury of small intestine	0.004	0.996	0.000
S36.3 Injury of stomach	0.004	0.996	0.000
S36.2 Injury of pancreas	0.004	0.996	0.000
S32.3 Fracture of ilium	0.004	0.996	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.004	0.996	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S35.5 Injury of iliac blood vessels	0.004	0.996	0.000
S35.4 Injury of renal blood vessels	0.004	0.996	0.000
S35.3 Injury of portal or splenic vein	0.004	0.996	0.000
S35.1 Injury of inferior vena cava	0.004	0.996	0.000
S35.0 Injury of abdominal aorta	0.004	0.996	0.000
S32.2 Fracture of coccyx	0.004	0.996	0.000
S32.41 Fracture of acetabulum (open)	0.004	0.996	0.000
N41 Inflammatory diseases of prostate	0.004	0.996	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.004	0.996	0.000
H49.1 Fourth [trochlear] nerve palsy	0.004	0.996	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.996	0.004
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.996	0.004
D52 Folate deficiency anaemia	0.004	0.996	0.000
H52 Disorders of refraction and accommodation	0.004	0.996	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.996	0.004
H52.3 Anisometropia and aniseikonia	0.004	0.996	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.004	0.996	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.996	0.004
S32.1 Fracture of sacrum	0.003	0.996	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.003	0.996	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.003	0.996	0.000
H52.1 Myopia	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.996	0.004
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.003	0.996	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.003	0.996	0.000
S33.5 Sprain and strain of lumbar spine	0.003	0.996	0.000
S33.4 Traumatic rupture of symphysis pubis	0.003	0.996	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.003	0.996	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.003	0.996	0.000
S33.1 Dislocation of lumbar vertebra	0.003	0.996	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.003	0.996	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.003	0.996	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.003	0.996	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.003	0.996	0.000
S34.4 Injury of lumbosacral plexus	0.003	0.996	0.000
S34.3 Injury of cauda equina	0.003	0.996	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.003	0.996	0.000
S34.1 Other injury of lumbar spinal cord	0.003	0.996	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.003	0.996	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.003	0.996	0.000
S38.2 Traumatic amputation of external genital organs	0.003	0.996	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.003	0.996	0.000
S38.0 Crushing injury of external genital organs	0.003	0.996	0.000
S30.2 Contusion of external genital organs	0.003	0.996	0.000
C77.8 Lymph nodes of multiple regions	0.003	0.997	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.997	0.003
S64.8 Injury of other nerves at wrist and hand level	0.000	0.997	0.003
M60-M63 Disorders of muscles	0.003	0.997	0.000
S37.9 Injury of unspecified pelvic organ	0.003	0.997	0.000
S37.8 Injury of other pelvic organs	0.003	0.997	0.000
S37.7 Injury of multiple pelvic organs	0.003	0.997	0.000
S37.6 Injury of uterus	0.003	0.997	0.000
S37.5 Injury of Fallopian tube	0.003	0.997	0.000
S37.4 Injury of ovary	0.003	0.997	0.000
S37.2 Injury of bladder	0.003	0.997	0.000
S37.1 Injury of ureter	0.003	0.997	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
S37.3 Injury of urethra	0.003	0.997	0.000
H49.4 Progressive external ophthalmoplegia	0.003	0.997	0.000
S37.0 Injury of kidney	0.003	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.997	0.003
H34.0 Transient retinal artery occlusion	0.003	0.997	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.003	0.997	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.003	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.003	0.997	0.000
H49.8 Other paralytic strabismus	0.003	0.997	0.000
H52.4 Presbyopia	0.003	0.997	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.997	0.003
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
H01.8 Other specified inflammation of eyelid	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
H49.3 Total (external) ophthalmoplegia	0.003	0.997	0.000
S32.51 Fracture of pubis (open)	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations