TreeWAS – Variant ID: rs11748684

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z92.2 Personal history of long-term (current) use of other medicaments	0.000	0.979	0.021
N85.2 Hypertrophy of uterus	0.020	0.980	0.000
M25.46 Effusion of joint (Lower leg)	0.014	0.986	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.013	0.987	0.000
N85.4 Malposition of uterus	0.013	0.987	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.988	0.000
M25.4 Effusion of joint	0.011	0.989	0.000
N85.0 Endometrial glandular hyperplasia	0.011	0.989	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.011	0.989	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.010	0.990	0.000
N85.1 Endometrial adenomatous hyperplasia	0.010	0.990	0.000
N85.6 Intra-uterine synechiae	0.010	0.990	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.010	0.990	0.000
S82.00 Fracture of patella (closed)	0.010	0.990	0.000
N85.7 Haematometra	0.009	0.990	0.000
N85.5 Inversion of uterus	0.009	0.990	0.000
N85.3 Subinvolution of uterus	0.009	0.990	0.000
S82.0 Fracture of patella	0.009	0.990	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.009	0.991	0.000
S82 Fracture of lower leg, including ankle	0.009	0.991	0.000
M25.42 Effusion of joint (Upper arm)	0.009	0.991	0.000
M25 Other joint disorders, not elsewhere classified	0.009	0.991	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.009	0.991	0.000
S82.2 Fracture of shaft of tibia	0.009	0.991	0.000
M25.47 Effusion of joint (Ankle and foot)	0.008	0.991	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.009	0.991	0.000
M25.49 Effusion of joint (Site unspecified)	0.008	0.991	0.000
M25.48 Effusion of joint (Other)	0.008	0.991	0.000
M25.44 Effusion of joint (Hand)	0.008	0.991	0.000
M25.43 Effusion of joint (Forearm)	0.008	0.991	0.000
M25.41 Effusion of joint (Shoulder region)	0.008	0.991	0.000
M25.40 Effusion of joint (Multiple sites)	0.008	0.991	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.008	0.992	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.008	0.992	0.000
N97.9 Female infertility, unspecified	0.000	0.992	0.008
S82.20 Fracture of shaft of tibia (closed)	0.008	0.992	0.000
S82.3 Fracture of lower end of tibia	0.008	0.992	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.008	0.992	0.000
S82.30 Fracture of lower end of tibia (closed)	0.008	0.992	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.008	0.992	0.000
M25.8 Other specified joint disorders	0.008	0.992	0.000
S82.8 Fractures of other parts of lower leg	0.008	0.992	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.008	0.992	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.008	0.992	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.008	0.992	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.007	0.992	0.000
B34.9 Viral infection, unspecified	0.007	0.993	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.007	0.993	0.000
S80-S89 Injuries to the knee and lower leg	0.007	0.993	0.000
M25.9 Joint disorder, unspecified	0.007	0.993	0.000
S82.01 Fracture of patella (open)	0.007	0.993	0.000
M25.56 Pain in joint (Lower leg)	0.007	0.993	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.007	0.993	0.000
S82.21 Fracture of shaft of tibia (open)	0.007	0.993	0.000
S82.9 Fracture of lower leg, part unspecified	0.007	0.993	0.000
S82.7 Multiple fractures of lower leg	0.007	0.993	0.000
S86 Injury of muscle and tendon at lower leg level	0.007	0.993	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.007	0.993	0.000
S82.5 Fracture of medial malleolus	0.007	0.993	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.007	0.993	0.000
M25.0 Haemarthrosis	0.007	0.993	0.000
M25.2 Flail joint	0.007	0.993	0.000
M25.1 Fistula of joint	0.007	0.993	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.007	0.993	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.006	0.993	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.007	0.993	0.000
M25.86 Other specified joint disorders (Lower leg)	0.006	0.994	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.006	0.994	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.006	0.994	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.006	0.994	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
M25.84 Other specified joint disorders (Hand)	0.006	0.994	0.000
S82.6 Fracture of lateral malleolus	0.006	0.994	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.006	0.994	0.000
S82.4 Fracture of fibula alone	0.006	0.994	0.000
M25.3 Other instability of joint	0.006	0.994	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.006	0.994	0.000
T79-T79 Certain early complications of trauma	0.006	0.994	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.006	0.994	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.006	0.994	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.006	0.994	0.000
M25.88 Other specified joint disorders (Other)	0.006	0.994	0.000
M25.83 Other specified joint disorders (Forearm)	0.006	0.994	0.000
M25.82 Other specified joint disorders (Upper arm)	0.006	0.994	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.006	0.994	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.006	0.994	0.000
M23 Internal derangement of knee	0.006	0.994	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.006	0.994	0.000
S82.86 Maisonneuve's fracture	0.006	0.994	0.000
S82.81 Fractures of other parts of lower leg (open)	0.006	0.994	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.006	0.994	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.006	0.994	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.006	0.994	0.000
S20-S29 Injuries to the thorax	0.006	0.994	0.000
S32.50 Fracture of pubis (closed)	0.006	0.994	0.000
S82.1 Fracture of upper end of tibia	0.006	0.994	0.000
S32 Fracture of lumbar spine and pelvis	0.006	0.994	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.006	0.994	0.000
T93 Sequelae of injuries of lower limb	0.006	0.994	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.006	0.994	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.006	0.994	0.000
S90-S99 Injuries to the ankle and foot	0.006	0.994	0.000
I47.2 Ventricular tachycardia	0.006	0.994	0.000
S32.5 Fracture of pubis	0.006	0.994	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.005	0.995	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
S60-S69 Injuries to the wrist and hand	0.005	0.995	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.005	0.995	0.000
S82.31 Fracture of lower end of tibia (open)	0.005	0.995	0.000
S88 Traumatic amputation of lower leg	0.005	0.995	0.000
S87 Crushing injury of lower leg	0.005	0.995	0.000
S85 Injury of blood vessels at lower leg level	0.005	0.995	0.000
S84 Injury of nerves at lower leg level	0.005	0.995	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.005	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.005	0.995	0.000
M25.98 Joint disorder, unspecified (Other)	0.005	0.995	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.005	0.995	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M25.94 Joint disorder, unspecified (Hand)	0.005	0.995	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.005	0.995	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.005	0.995	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.005	0.995	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.005	0.995	0.000
M16.9 Coxarthrosis, unspecified	0.005	0.995	0.000
M23.8 Other internal derangements of knee	0.005	0.995	0.000
M23.0 Cystic meniscus	0.005	0.995	0.000
S70-S79 Injuries to the hip and thigh	0.005	0.995	0.000
S82.71 Multiple fractures of lower leg (open)	0.005	0.995	0.000
S82.70 Multiple fractures of lower leg (closed)	0.005	0.995	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.005	0.995	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.005	0.995	0.000
S86.0 Injury of Achilles tendon	0.005	0.995	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.005	0.995	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.005	0.995	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.005	0.995	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.005	0.995	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.005	0.995	0.000
S50-S59 Injuries to the elbow and forearm	0.005	0.995	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.005	0.995	0.000
S82.51 Fracture of medial malleolus (open)	0.005	0.995	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.005	0.995	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.995	0.000
M25.7 Osteophyte	0.005	0.995	0.000
S89 Other and unspecified injuries of lower leg	0.005	0.995	0.000
I31.9 Disease of pericardium, unspecified	0.005	0.995	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.005	0.995	0.000
M25.09 Haemarthrosis (Site unspecified)	0.005	0.995	0.000
M25.08 Haemarthrosis (Other)	0.005	0.995	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.005	0.995	0.000
M25.06 Haemarthrosis (Lower leg)	0.005	0.995	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.005	0.995	0.000
M25.04 Haemarthrosis (Hand)	0.005	0.995	0.000
M25.03 Haemarthrosis (Forearm)	0.005	0.995	0.000
M25.02 Haemarthrosis (Upper arm)	0.005	0.995	0.000
M25.01 Haemarthrosis (Shoulder region)	0.005	0.995	0.000
M25.00 Haemarthrosis (Multiple sites)	0.005	0.995	0.000
M25.19 Fistula of joint (Site unspecified)	0.005	0.995	0.000
M25.18 Fistula of joint (Other)	0.005	0.995	0.000
M25.17 Fistula of joint (Ankle and foot)	0.005	0.995	0.000
M25.16 Fistula of joint (Lower leg)	0.005	0.995	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.005	0.995	0.000
M25.14 Fistula of joint (Hand)	0.005	0.995	0.000
M25.13 Fistula of joint (Forearm)	0.005	0.995	0.000
M25.12 Fistula of joint (Upper arm)	0.005	0.995	0.000
M25.11 Fistula of joint (Shoulder region)	0.005	0.995	0.000
M25.10 Fistula of joint (Multiple sites)	0.005	0.995	0.000
M25.29 Flail joint (Site unspecified)	0.005	0.995	0.000
M25.28 Flail joint (Other)	0.005	0.995	0.000
M25.27 Flail joint (Ankle and foot)	0.005	0.995	0.000
M25.26 Flail joint (Lower leg)	0.005	0.995	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.005	0.995	0.000
M25.24 Flail joint (Hand)	0.005	0.995	0.000
M25.23 Flail joint (Forearm)	0.005	0.995	0.000
M25.22 Flail joint (Upper arm)	0.005	0.995	0.000
M25.21 Flail joint (Shoulder region)	0.005	0.995	0.000
M25.20 Flail joint (Multiple sites)	0.005	0.995	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.005	0.995	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.005	0.995	0.000
S29 Other and unspecified injuries of thorax	0.005	0.995	0.000
T79.7 Traumatic subcutaneous emphysema	0.005	0.995	0.000
B34 Viral infection of unspecified site	0.005	0.995	0.000
S72.00 Fracture of neck of femur (closed)	0.005	0.995	0.000
M23.1 Discoid meniscus (congenital)	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
S31 Open wound of abdomen, lower back and pelvis	0.005	0.995	0.000
M20-M25 Other joint disorders	0.005	0.995	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.005	0.995	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.005	0.995	0.000
T21 Burn and corrosion of trunk	0.005	0.995	0.000
S72 Fracture of femur	0.005	0.995	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.005	0.995	0.000
I47 Paroxysmal tachycardia	0.005	0.995	0.000
T98 Sequelae of other and unspecified effects of external causes	0.005	0.995	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.005	0.995	0.000
S82.61 Fracture of lateral malleolus (open)	0.005	0.995	0.000
S63.6 Sprain and strain of finger(s)	0.005	0.995	0.000
S72.0 Fracture of neck of femur	0.005	0.995	0.000
S91 Open wound of ankle and foot	0.005	0.995	0.000
T33-T35 Frostbite	0.005	0.995	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.005	0.995	0.000
T00-T07 Injuries involving multiple body regions	0.005	0.995	0.000
T79.6 Traumatic ischaemia of muscle	0.005	0.995	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.005	0.995	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.005	0.995	0.000
T79.8 Other early complications of trauma	0.005	0.995	0.000
S82.41 Fracture of fibula alone (open)	0.005	0.995	0.000
S32.3 Fracture of ilium	0.005	0.995	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.005	0.995	0.000
S37 Injury of urinary and pelvic organs	0.005	0.995	0.000
S20 Superficial injury of thorax	0.005	0.995	0.000
M25.39 Other instability of joint (Site unspecified)	0.004	0.995	0.000
M25.38 Other instability of joint (Other)	0.004	0.995	0.000
M25.37 Other instability of joint (Ankle and foot)	0.005	0.995	0.000
M25.36 Other instability of joint (Lower leg)	0.004	0.995	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.34 Other instability of joint (Hand)	0.004	0.995	0.000
M25.33 Other instability of joint (Forearm)	0.004	0.995	0.000
M25.32 Other instability of joint (Upper arm)	0.004	0.995	0.000
M25.30 Other instability of joint (Multiple sites)	0.004	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
S40-S49 Injuries to the shoulder and upper arm	0.005	0.995	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
S36 Injury of intra-abdominal organs	0.005	0.995	0.000
T91 Sequelae of injuries of neck and trunk	0.005	0.995	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.005	0.995	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.005	0.995	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.005	0.995	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.005	0.995	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
M23.9 Internal derangement of knee, unspecified	0.005	0.995	0.000
T93.1 Sequelae of fracture of femur	0.005	0.995	0.000
I31 Other diseases of pericardium	0.005	0.995	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
I31.3 Pericardial effusion (noninflammatory)	0.005	0.995	0.000
S22.2 Fracture of sternum	0.004	0.995	0.000
T79.9 Unspecified early complication of trauma	0.004	0.995	0.000
T79.5 Traumatic anuria	0.004	0.995	0.000
T79.4 Traumatic shock	0.004	0.995	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.004	0.995	0.000
T79.1 Fat embolism (traumatic)	0.004	0.995	0.000
T79.0 Air embolism (traumatic)	0.004	0.995	0.000
T23 Burn and corrosion of wrist and hand	0.005	0.995	0.000
T93.2 Sequelae of other fractures of lower limb	0.005	0.995	0.000
T20 Burn and corrosion of head and neck	0.004	0.995	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
S32.1 Fracture of sacrum	0.004	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.004	0.995	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.005	0.995	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.004	0.995	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.005	0.995	0.000
M24.5 Contracture of joint	0.004	0.995	0.000
S29.9 Unspecified injury of thorax	0.004	0.995	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.005	0.995	0.000
I42 Cardiomyopathy	0.005	0.995	0.000
T66-T78 Other and unspecified effects of external causes	0.004	0.995	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.005	0.995	0.000
M23.5 Chronic instability of knee	0.004	0.995	0.000
S63.0 Dislocation of wrist	0.004	0.995	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.004	0.995	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.995	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.004	0.995	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.004	0.995	0.000
S56 Injury of muscle and tendon at forearm level	0.004	0.995	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.995	0.000
M24.0 Loose body in joint	0.004	0.995	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.004	0.996	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
T92 Sequelae of injuries of upper limb	0.004	0.996	0.000
W00-W19 Falls	0.004	0.996	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.004	0.996	0.000
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
T95 Sequelae of burns, corrosions and frostbite	0.004	0.996	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
S92 Fracture of foot, except ankle	0.004	0.996	0.000
B34.4 Papovirus infection, unspecified	0.004	0.996	0.000
T25 Burn and corrosion of ankle and foot	0.004	0.996	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.004	0.996	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.004	0.996	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.004	0.996	0.000
S22.20 Fracture of sternum (closed)	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.004	0.996	0.000
S90 Superficial injury of ankle and foot	0.004	0.996	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.004	0.996	0.000
S26 Injury of heart	0.004	0.996	0.000
S25 Injury of blood vessels of thorax	0.004	0.996	0.000
S24 Injury of nerves and spinal cord at thorax level	0.004	0.996	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.004	0.996	0.000
S21 Open wound of thorax	0.004	0.996	0.000
S82.11 Fracture of upper end of tibia (open)	0.004	0.996	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
S32.2 Fracture of coccyx	0.004	0.996	0.000
J33.9 Nasal polyp, unspecified	0.000	0.996	0.004
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.004	0.996	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.004	0.996	0.000
S98 Traumatic amputation of ankle and foot	0.004	0.996	0.000
S97 Crushing injury of ankle and foot	0.004	0.996	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.996	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.996	0.000
S10-S19 Injuries to the neck	0.004	0.996	0.000
S54 Injury of nerves at forearm level	0.004	0.996	0.000
S32.51 Fracture of pubis (open)	0.004	0.996	0.000
S50 Superficial injury of forearm	0.004	0.996	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.004	0.996	0.000
S22.4 Multiple fractures of ribs	0.004	0.996	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.004	0.996	0.000
E29.1 Testicular hypofunction	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
M25.31 Other instability of joint (Shoulder region)	0.004	0.996	0.000
S32.0 Fracture of lumbar vertebra	0.004	0.996	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.004	0.996	0.000
S22.0 Fracture of thoracic vertebra	0.004	0.996	0.000
W19 Unspecified fall	0.004	0.996	0.000
S65 Injury of blood vessels at wrist and hand level	0.004	0.996	0.000
S99 Other and unspecified injuries of ankle and foot	0.004	0.996	0.000
T81 Complications of procedures, not elsewhere classified	0.004	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.004	0.996	0.000
S31.0 Open wound of lower back and pelvis	0.004	0.996	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.004	0.996	0.000
S84.8 Injury of other nerves at lower leg level	0.004	0.996	0.000
S84.7 Injury of multiple nerves at lower leg level	0.004	0.996	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.004	0.996	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.004	0.996	0.000
S84.0 Injury of tibial nerve at lower leg level	0.004	0.996	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.004	0.996	0.000
S85.8 Injury of other blood vessels at lower leg level	0.004	0.996	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.004	0.996	0.000
S85.5 Injury of popliteal vein	0.004	0.996	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.004	0.996	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.004	0.996	0.000
S85.2 Injury of peroneal artery	0.004	0.996	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.004	0.996	0.000
S85.0 Injury of popliteal artery	0.004	0.996	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.004	0.996	0.000
S87.0 Crushing injury of knee	0.004	0.996	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.004	0.996	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.004	0.996	0.000
S88.0 Traumatic amputation at knee level	0.004	0.996	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.996	0.000
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
T21.2 Burn of second degree of trunk	0.004	0.996	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.004	0.996	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.004	0.996	0.000
T21.0 Burn of unspecified degree of trunk	0.004	0.996	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.004	0.996	0.000
S32.30 Fracture of ilium (closed)	0.004	0.996	0.000
I42.6 Alcoholic cardiomyopathy	0.004	0.996	0.000
S91.3 Open wound of other parts of foot	0.004	0.996	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.004	0.996	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.004	0.996	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.004	0.996	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.004	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.004	0.996	0.000
S51 Open wound of forearm	0.004	0.996	0.000
T86 Failure and rejection of transplanted organs and tissues	0.004	0.996	0.000
M23.07 Cystic meniscus-Capsular lig	0.004	0.996	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.004	0.996	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
M23.00 Cystic meniscus (Multiple sites)	0.004	0.996	0.000
S82.40 Fracture of fibula alone (closed)	0.004	0.996	0.000
T88.5 Other complications of anaesthesia	0.004	0.996	0.000
M25.72 Osteophyte (Upper arm)	0.004	0.996	0.000
M23.4 Loose body in knee	0.004	0.996	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.004	0.996	0.000
S78 Traumatic amputation of hip and thigh	0.004	0.996	0.000
S77 Crushing injury of hip and thigh	0.004	0.996	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.004	0.996	0.000
S75 Injury of blood vessels at hip and thigh level	0.004	0.996	0.000
S74 Injury of nerves at hip and thigh level	0.004	0.996	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
S86.00 Unspecified injury of Achilles tendon	0.004	0.996	0.000
S32.4 Fracture of acetabulum	0.004	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.004	0.996	0.000
V18.0 Driver injured in nontraffic accident	0.004	0.996	0.000
S59 Other and unspecified injuries of forearm	0.004	0.996	0.000
S58 Traumatic amputation of forearm	0.004	0.996	0.000
S57 Crushing injury of forearm	0.004	0.996	0.000
S55 Injury of blood vessels at forearm level	0.004	0.996	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.004	0.996	0.000
S70 Superficial injury of hip and thigh	0.004	0.996	0.000
W18 Other fall on same level	0.004	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.004	0.996	0.000
S83.7 Injury to multiple structures of knee	0.004	0.996	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.004	0.996	0.000
S83.3 Tear of articular cartilage of knee, current	0.004	0.996	0.000
S83.1 Dislocation of knee	0.004	0.996	0.000
S83.0 Dislocation of patella	0.004	0.996	0.000
T66 Unspecified effects of radiation	0.004	0.996	0.000
S63.1 Dislocation finger	0.004	0.996	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.004	0.996	0.000
S63.5 Sprain and strain of wrist	0.004	0.996	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.004	0.996	0.000
S63.2 Multiple dislocations of fingers	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.996	0.000
M25.79 Osteophyte (Site unspecified)	0.004	0.996	0.000
M25.73 Osteophyte (Forearm)	0.004	0.996	0.000
M25.70 Osteophyte (Multiple sites)	0.004	0.996	0.000
S22.5 Flail chest	0.004	0.996	0.000
S72.1 Pertrochanteric fracture	0.004	0.996	0.000
M25.71 Osteophyte (Shoulder region)	0.004	0.996	0.000
W19.3 Sports and athletics area	0.004	0.996	0.000
M30 Polyarteritis nodosa and related conditions	0.004	0.996	0.000
W14 Fall from tree	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M25.77 Osteophyte (Ankle and foot)	0.004	0.996	0.000
S89.8 Other specified injuries of lower leg	0.004	0.996	0.000
S89.7 Multiple injuries of lower leg	0.004	0.996	0.000
S89.1 Other specified injuries of lower leg	0.004	0.996	0.000
S89.0 Multiple injuries of lower leg	0.004	0.996	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.004	0.996	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.004	0.996	0.000
W00 Fall on same level involving ice and snow	0.004	0.996	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.004	0.996	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.004	0.996	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.004	0.996	0.000
S81 Open wound of lower leg	0.004	0.996	0.000
W10 Fall on and from stairs and steps	0.004	0.996	0.000
W07 Fall involving chair	0.004	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.004	0.996	0.000
S22.8 Fracture of other parts of bony thorax	0.004	0.996	0.000
S72.4 Fracture of lower end of femur	0.004	0.996	0.000
B34.3 Parvovirus infection, unspecified	0.004	0.996	0.000
B34.2 Coronavirus infection, unspecified	0.004	0.996	0.000
B34.1 Enterovirus infection, unspecified	0.004	0.996	0.000
B34.0 Adenovirus infection, unspecified	0.004	0.996	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.004	0.996	0.000
S29.8 Other specified injuries of thorax	0.004	0.996	0.000
S29.7 Multiple injuries of thorax	0.004	0.996	0.000
S29.0 Injury of muscle and tendon at thorax level	0.004	0.996	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.004	0.996	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.004	0.996	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.004	0.996	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.004	0.996	0.000
M24.54 Contracture of joint (Hand)	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M25.5 Pain in joint	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.004	0.996	0.000
N97 Female infertility	0.000	0.996	0.004
T68 Hypothermia	0.004	0.996	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.004	0.996	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.004	0.996	0.000
S31.5 Open wound of other and unspecified external genital organs	0.004	0.996	0.000
S31.4 Open wound of vagina and vulva	0.004	0.996	0.000
S31.3 Open wound of scrotum and testes	0.004	0.996	0.000
S31.2 Open wound of penis	0.004	0.996	0.000
S31.1 Open wound of abdominal wall	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.004	0.996	0.000
I42.2 Other hypertrophic cardiomyopathy	0.004	0.996	0.000
T21.7 Corrosion of third degree of trunk	0.004	0.996	0.000
T21.6 Corrosion of second degree of trunk	0.004	0.996	0.000
T21.5 Corrosion of first degree of trunk	0.004	0.996	0.000
T21.4 Corrosion of unspecified degree of trunk	0.004	0.996	0.000
T21.3 Burn of third degree of trunk	0.004	0.996	0.000
T21.1 Burn of first degree of trunk	0.004	0.996	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.004	0.996	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.004	0.996	0.000
M33 Dermatopolymyositis	0.004	0.996	0.000
M32 Systemic lupus erythematosus	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
S32.10 Fracture of sacrum (closed)	0.004	0.996	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.004	0.996	0.000
S72.9 Fracture of femur, part unspecified	0.004	0.996	0.000
S72.8 Fractures of other parts of femur	0.004	0.996	0.000
S72.7 Multiple fractures of femur	0.004	0.996	0.000
S79 Other and unspecified injuries of hip and thigh	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations