TreeWAS – Variant ID: rs117530689

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K22 Other diseases of oesophagus	0.077	0.923	0.000
K22.1 Ulcer of oesophagus	0.077	0.923	0.000
K22.9 Disease of oesophagus, unspecified	0.076	0.924	0.000
K22.7 Barrett's oesophagus	0.073	0.927	0.000
K22.8 Other specified diseases of oesophagus	0.071	0.929	0.000
K22.5 Diverticulum of oesophagus, acquired	0.057	0.942	0.000
K22.4 Dyskinesia of oesophagus	0.057	0.943	0.000
K22.3 Perforation of oesophagus	0.055	0.945	0.000
K22.0 Achalasia of cardia	0.055	0.945	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.051	0.948	0.000
K22.2 Oesophageal obstruction	0.033	0.967	0.000
O36 Maternal care for other known or suspected foetal problems	0.017	0.983	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.016	0.984	0.000
O36.4 Maternal care for intra-uterine death	0.015	0.985	0.000
R42 Dizziness and giddiness	0.015	0.985	0.000
O36.6 Maternal care for excessive foetal growth	0.015	0.985	0.000
O36.5 Maternal care for poor foetal growth	0.015	0.985	0.000
O36.9 Maternal care for foetal problem, unspecified	0.015	0.985	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.014	0.986	0.000
O36.8 Maternal care for other specified foetal problems	0.014	0.986	0.000
O46.9 Antepartum haemorrhage, unspecified	0.014	0.986	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.013	0.987	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.013	0.987	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.013	0.987	0.000
I95.1 Orthostatic hypotension	0.013	0.987	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.013	0.987	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.013	0.987	0.000
O36.2 Maternal care for hydrops foetalis	0.013	0.987	0.000
O36.1 Maternal care for other isoimmunisation	0.013	0.987	0.000
O42 Premature rupture of membranes	0.013	0.987	0.000
O43 Placental disorders	0.013	0.987	0.000
O00-O08 Pregnancy with abortive outcome	0.013	0.987	0.000
I95 Hypotension	0.012	0.988	0.000
O04 Medical abortion	0.012	0.988	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.012	0.988	0.000
I95.2 Hypotension due to drugs	0.012	0.988	0.000
O44 Placenta praevia	0.012	0.988	0.000
O04.9 Complete or unspecified, without complication	0.012	0.988	0.000
O45 Premature separation of placenta [abruptio placentae]	0.012	0.988	0.000
O33 Maternal care for known or suspected disproportion	0.012	0.988	0.000
O31 Complications specific to multiple gestation	0.012	0.988	0.000
O47 False labour	0.011	0.989	0.000
O40 Polyhydramnios	0.011	0.989	0.000
O41 Other disorders of amniotic fluid and membranes	0.011	0.989	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.011	0.989	0.000
R40 Somnolence, stupor and coma	0.011	0.989	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.011	0.989	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.011	0.989	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.011	0.989	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.011	0.989	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.011	0.989	0.000
O46.8 Other antepartum haemorrhage	0.010	0.989	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.010	0.989	0.000
O34.1 Maternal care for tumour of corpus uteri	0.010	0.989	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.010	0.989	0.000
I95.0 Idiopathic hypotension	0.010	0.990	0.000
R45 Symptoms and signs involving emotional state	0.010	0.990	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.010	0.990	0.000
O02 Other abnormal products of conception	0.010	0.990	0.000
O00 Ectopic pregnancy	0.010	0.990	0.000
R54 Senility	0.010	0.990	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.010	0.990	0.000
I95.8 Other hypotension	0.010	0.990	0.000
R40.0 Somnolence	0.010	0.990	0.000
O43.8 Other placental disorders	0.010	0.990	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.010	0.990	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.010	0.990	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.010	0.990	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.010	0.990	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.010	0.990	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.010	0.990	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.010	0.990	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.010	0.990	0.000
O30 Multiple gestation	0.010	0.990	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.010	0.990	0.000
O03 Spontaneous abortion	0.010	0.990	0.000
R46 Symptoms and signs involving appearance and behaviour	0.010	0.990	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.010	0.990	0.000
O34.6 Maternal care for abnormality of vagina	0.010	0.990	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.010	0.990	0.000
O34.4 Maternal care for other abnormalities of cervix	0.010	0.990	0.000
O34.3 Maternal care for cervical incompetence	0.010	0.990	0.000
O34.0 Maternal care for congenital malformation of uterus	0.010	0.990	0.000
O43.1 Malformation of placenta	0.010	0.990	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.009	0.990	0.000
O44.1 Placenta praevia with haemorrhage	0.009	0.990	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.009	0.991	0.000
R55 Syncope and collapse	0.009	0.991	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.009	0.991	0.000
O48 Prolonged pregnancy	0.009	0.991	0.000
O43.9 Placental disorder, unspecified	0.009	0.991	0.000
O43.2 Morbidly adherent placenta	0.009	0.991	0.000
O43.0 Placental transfusion syndromes	0.009	0.991	0.000
O07 Failed attempted abortion	0.009	0.991	0.000
O06 Unspecified abortion	0.009	0.991	0.000
O05 Other abortion	0.009	0.991	0.000
O01 Hydatidiform mole	0.009	0.991	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.009	0.991	0.000
O47.0 False labour before 37 completed weeks of gestation	0.009	0.991	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.009	0.991	0.000
O04.7 Complete or unspecified, complicated by embolism	0.009	0.991	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.009	0.991	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.009	0.991	0.000
O04.4 Incomplete, without complication	0.009	0.991	0.000
O04.3 Incomplete, with other and unspecified complications	0.009	0.991	0.000
O04.2 Incomplete, complicated by embolism	0.009	0.991	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.009	0.991	0.000
R43 Disturbances of smell and taste	0.009	0.991	0.000
O02.1 Missed abortion	0.009	0.991	0.000
O03.4 Incomplete, without complication	0.009	0.991	0.000
R45.2 Unhappiness	0.009	0.991	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.009	0.991	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.009	0.991	0.000
O00.1 Tubal pregnancy	0.009	0.991	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.009	0.991	0.000
R40.2 Coma, unspecified	0.009	0.991	0.000
O31.8 Other complications specific to multiple gestation	0.008	0.991	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.008	0.991	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.008	0.991	0.000
O31.0 Papyraceous foetus	0.008	0.991	0.000
O33.9 Maternal care for disproportion, unspecified	0.008	0.991	0.000
O33.8 Maternal care for disproportion of other origin	0.008	0.991	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.008	0.991	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.008	0.991	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.008	0.991	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.008	0.991	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.008	0.991	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.008	0.991	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.008	0.991	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.008	0.991	0.000
O45.9 Premature separation of placenta, unspecified	0.008	0.991	0.000
O45.8 Other premature separation of placenta	0.008	0.991	0.000
O45.0 Premature separation of placenta with coagulation defect	0.008	0.991	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.009	0.991	0.000
O85-O92 Complications predominantly related to the puerperium	0.009	0.991	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.008	0.991	0.000
I95.9 Hypotension, unspecified	0.008	0.992	0.000
R45.1 Restlessness and agitation	0.008	0.992	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.008	0.992	0.000
O41.1 Infection of amniotic sac and membranes	0.008	0.992	0.000
I44.7 Left bundle-branch block, unspecified	0.008	0.992	0.000
R40.1 Stupor	0.008	0.992	0.000
O42.9 Premature rupture of membranes, unspecified	0.008	0.992	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.008	0.992	0.000
R50-R69 General symptoms and signs	0.008	0.992	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
R29.6 Tendency to fall, not elsewhere classified	0.008	0.992	0.000
O00.9 Ectopic pregnancy, unspecified	0.008	0.992	0.000
R45.7 State of emotional shock and stress, unspecified	0.008	0.992	0.000
R45.6 Physical violence	0.008	0.992	0.000
R45.5 Hostility	0.008	0.992	0.000
R45.4 Irritability and anger	0.008	0.992	0.000
R45.3 Demoralisation and apathy	0.008	0.992	0.000
R45.0 Nervousness	0.008	0.992	0.000
O02.9 Abnormal product of conception, unspecified	0.008	0.992	0.000
O02.8 Other specified abnormal products of conception	0.008	0.992	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.008	0.992	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.008	0.992	0.000
O00.8 Other ectopic pregnancy	0.008	0.992	0.000
O00.2 Ovarian pregnancy	0.008	0.992	0.000
O00.0 Abdominal pregnancy	0.008	0.992	0.000
R44.1 Visual hallucinations	0.007	0.992	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.007	0.992	0.000
O41.0 Oligohydramnios	0.007	0.993	0.000
R44.2 Other hallucinations	0.007	0.993	0.000
R44.0 Auditory hallucinations	0.007	0.993	0.000
O30.9 Multiple gestation, unspecified	0.007	0.993	0.000
O30.8 Other multiple gestation	0.007	0.993	0.000
O30.2 Quadruplet pregnancy	0.007	0.993	0.000
O30.1 Triplet pregnancy	0.007	0.993	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.007	0.993	0.000
O03.7 Complete or unspecified, complicated by embolism	0.007	0.993	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O03.3 Incomplete, with other and unspecified complications	0.007	0.993	0.000
O03.2 Incomplete, complicated by embolism	0.007	0.993	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.007	0.993	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.007	0.993	0.000
R46.6 Undue concern and preoccupation with stressful events	0.007	0.993	0.000
R46.5 Suspiciousness and marked evasiveness	0.007	0.993	0.000
R46.4 Slowness and poor responsiveness	0.007	0.993	0.000
R46.3 Overactivity	0.007	0.993	0.000
R46.2 Strange and inexplicable behaviour	0.007	0.993	0.000
R46.1 Bizarre personal appearance	0.007	0.993	0.000
R46.0 Very low level of personal hygiene	0.007	0.993	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.007	0.993	0.000
E86 Volume depletion	0.007	0.993	0.000
R68 Other general symptoms and signs	0.007	0.993	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.007	0.993	0.000
O32.8 Maternal care for other malpresentation of foetus	0.007	0.993	0.000
O32.6 Maternal care for compound presentation	0.007	0.993	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.007	0.993	0.000
O32.4 Maternal care for high head at term	0.007	0.993	0.000
O32.3 Maternal care for face, brow and chin presentation	0.007	0.993	0.000
O32.2 Maternal care for transverse and oblique lie	0.007	0.993	0.000
O32.0 Maternal care for unstable lie	0.007	0.993	0.000
O90 Complications of the puerperium, not elsewhere classified	0.007	0.993	0.000
O14.9 Preeclampsia, unspecified	0.007	0.993	0.000
R45.8 Other symptoms and signs involving emotional state	0.007	0.993	0.000
O01.9 Hydatidiform mole, unspecified	0.007	0.993	0.000
O01.1 Incomplete and partial hydatidiform mole	0.007	0.993	0.000
O01.0 Classical hydatidiform mole	0.007	0.993	0.000
O05.9 Complete or unspecified, without complication	0.007	0.993	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.007	0.993	0.000
O05.7 Complete or unspecified, complicated by embolism	0.007	0.993	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O05.4 Incomplete, without complication	0.007	0.993	0.000
O05.3 Incomplete, with other and unspecified complications	0.007	0.993	0.000
O05.2 Incomplete, complicated by embolism	0.007	0.993	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O06.9 Complete or unspecified, without complication	0.007	0.993	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.007	0.993	0.000
O06.7 Complete or unspecified, complicated by embolism	0.007	0.993	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O06.4 Incomplete, without complication	0.007	0.993	0.000
O06.3 Incomplete, with other and unspecified complications	0.007	0.993	0.000
O06.2 Incomplete, complicated by embolism	0.007	0.993	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.007	0.993	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.007	0.993	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.007	0.993	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O07.4 Failed medical abortion, without complication	0.007	0.993	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.007	0.993	0.000
O07.2 Failed medical abortion, complicated by embolism	0.007	0.993	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.007	0.993	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.007	0.993	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O97 Death from sequelae of direct obstetric causes	0.007	0.993	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.007	0.993	0.000
O95 Obstetric death of unspecified cause	0.007	0.993	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.007	0.993	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.007	0.993	0.000
R43.2 Parageusia	0.007	0.993	0.000
R43.1 Parosmia	0.007	0.993	0.000
R43.0 Anosmia	0.007	0.993	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.007	0.993	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.007	0.993	0.000
O47.9 False labour, unspecified	0.006	0.993	0.000
K31.7 Polyp of stomach and duodenum	0.007	0.993	0.000
R50 Fever of unknown origin	0.007	0.993	0.000
R52 Pain, not elsewhere classified	0.007	0.993	0.000
R56 Convulsions, not elsewhere classified	0.006	0.993	0.000
R44.3 Hallucinations, unspecified	0.006	0.993	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.000	0.994	0.006
O92 Other disorders of breast and lactation associated with childbirth	0.006	0.994	0.000
O91 Infections of breast associated with childbirth	0.006	0.994	0.000
O89 Complications of anaesthesia during the puerperium	0.006	0.994	0.000
O88 Obstetric embolism	0.006	0.994	0.000
O87 Venous complications in the puerperium	0.006	0.994	0.000
O86 Other puerperal infections	0.006	0.994	0.000
O85 Puerperal sepsis	0.006	0.994	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.006	0.994	0.000
R68.8 Other specified general symptoms and signs	0.006	0.994	0.000
J18.1 Lobar pneumonia, unspecified	0.006	0.994	0.000
O14.0 Moderate preeclampsia	0.006	0.994	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.006	0.994	0.000
R53 Malaise and fatigue	0.006	0.994	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
H93.1 Tinnitus	0.006	0.994	0.000
R57 Shock, not elsewhere classified	0.006	0.994	0.000
O80-O84 Delivery	0.006	0.994	0.000
R50.0 Fever with chills	0.006	0.994	0.000
R52.1 Chronic intractable pain	0.006	0.994	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.006	0.994	0.000
R62 Lack of expected normal physiological development	0.006	0.994	0.000
R64 Cachexia	0.006	0.994	0.000
R58 Haemorrhage, not elsewhere classified	0.006	0.994	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.006	0.994	0.000
M25.51 Pain in joint (Shoulder region)	0.006	0.994	0.000
I44 Atrioventricular and left bundle-branch block	0.006	0.994	0.000
K90.0 Coeliac disease	0.006	0.994	0.000
R50.8 Other specified fever	0.006	0.994	0.000
I47.2 Ventricular tachycardia	0.006	0.994	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.006	0.994	0.000
O30.0 Twin pregnancy	0.005	0.994	0.000
O15 Eclampsia	0.005	0.994	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.005	0.994	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.005	0.994	0.000
J33.9 Nasal polyp, unspecified	0.000	0.994	0.006
I44.1 Atrioventricular block, second degree	0.006	0.994	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.006	0.994	0.000
O14.2 HELLP syndrome	0.005	0.994	0.000
O14.1 Severe preeclampsia	0.005	0.994	0.000
R41.0 Disorientation, unspecified	0.005	0.994	0.000
R56.8 Other and unspecified convulsions	0.005	0.995	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.005	0.995	0.000
R68.3 Clubbing of fingers	0.005	0.995	0.000
R68.2 Dry mouth, unspecified	0.005	0.995	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.005	0.995	0.000
R51 Headache	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.005	0.995	0.000
O90.9 Complication of the puerperium, unspecified	0.005	0.995	0.000
O90.5 Postpartum thyroiditis	0.005	0.995	0.000
O90.4 Postpartum acute renal failure	0.005	0.995	0.000
O90.3 Cardiomyopathy in the puerperium	0.005	0.995	0.000
O90.2 Haematoma of obstetric wound	0.005	0.995	0.000
O90.1 Disruption of perineal obstetric wound	0.005	0.995	0.000
O90.0 Disruption of Caesarean section wound	0.005	0.995	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.005	0.995	0.000
R80 Isolated proteinuria	0.005	0.995	0.000
R41.2 Retrograde amnesia	0.005	0.995	0.000
O96.9 Death from unspecified obstetric cause	0.005	0.995	0.000
O96.1 Death from indirect obstetric cause	0.005	0.995	0.000
O96.0 Death from direct obstetric cause	0.005	0.995	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.005	0.995	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.005	0.995	0.000
O97.0 Death from sequelae of direct obstetric cause	0.005	0.995	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
R41.1 Anterograde amnesia	0.005	0.995	0.000
O03.9 Complete or unspecified, without complication	0.005	0.995	0.000
R52.9 Pain, unspecified	0.005	0.995	0.000
I47.1 Supraventricular tachycardia	0.005	0.995	0.000
R50.2 Drug-induced fever	0.005	0.995	0.000
R50.1 Persistent fever	0.005	0.995	0.000
I47 Paroxysmal tachycardia	0.005	0.995	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.005	0.995	0.000
O32.1 Maternal care for breech presentation	0.005	0.995	0.000
I99 Other and unspecified disorders of circulatory system	0.005	0.995	0.000
R56.0 Febrile convulsions	0.005	0.995	0.000
E89.0 Postprocedural hypothyroidism	0.005	0.995	0.000
O86.8 Other specified puerperal infections	0.005	0.995	0.000
O86.4 Pyrexia of unknown origin following delivery	0.005	0.995	0.000
O86.3 Other genito-urinary tract infections following delivery	0.005	0.995	0.000
O86.2 Urinary tract infection following delivery	0.005	0.995	0.000
O86.1 Other infection of genital tract following delivery	0.005	0.995	0.000
O86.0 Infection of obstetric surgical wound	0.005	0.995	0.000
O87.9 Venous complication in the puerperium, unspecified	0.005	0.995	0.000
O87.8 Other venous complications in the puerperium	0.005	0.995	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.005	0.995	0.000
O87.2 Haemorrhoids in the puerperium	0.005	0.995	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.005	0.995	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.005	0.995	0.000
O88.8 Other obstetric embolism	0.005	0.995	0.000
O88.3 Obstetric pyaemic and septic embolism	0.005	0.995	0.000
O88.2 Obstetric blood-clot embolism	0.005	0.995	0.000
O88.1 Amniotic fluid embolism	0.005	0.995	0.000
O88.0 Obstetric air embolism	0.005	0.995	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.005	0.995	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.005	0.995	0.000
O89.6 Failed or difficult intubation during the puerperium	0.005	0.995	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.005	0.995	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.005	0.995	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.005	0.995	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.005	0.995	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.005	0.995	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.005	0.995	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.005	0.995	0.000
O91.1 Abscess of breast associated with childbirth	0.005	0.995	0.000
O91.0 Infection of nipple associated with childbirth	0.005	0.995	0.000
O92.7 Other and unspecified disorders of lactation	0.005	0.995	0.000
O92.6 Galactorrhoea	0.005	0.995	0.000
O92.5 Suppressed lactation	0.005	0.995	0.000
O92.4 Hypogalactia	0.005	0.995	0.000
O92.3 Agalactia	0.005	0.995	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.005	0.995	0.000
O92.1 Cracked nipple associated with childbirth	0.005	0.995	0.000
O92.0 Retracted nipple associated with childbirth	0.005	0.995	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.005	0.995	0.000
R61 Hyperhidrosis	0.005	0.995	0.000
R52.0 Acute pain	0.005	0.995	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.005	0.995	0.000
R60 Oedema, not elsewhere classified	0.005	0.995	0.000
R57.2 Septic shock	0.004	0.995	0.000
E70-E90 Metabolic disorders	0.005	0.995	0.000
I44.6 Other and unspecified fascicular block	0.005	0.995	0.000
R57.9 Shock, unspecified	0.004	0.995	0.000
R57.8 Other shock	0.004	0.995	0.000
R57.1 Hypovolaemic shock	0.004	0.995	0.000
R57.0 Cardiogenic shock	0.004	0.995	0.000
O84 Multiple delivery	0.004	0.995	0.000
O83 Other assisted single delivery	0.004	0.995	0.000
O81 Single delivery by forceps and vacuum extractor	0.004	0.995	0.000
R62.9 Lack of expected normal physiological development, unspecified	0.004	0.995	0.000
R62.8 Other lack of expected normal physiological development	0.004	0.995	0.000
R62.0 Delayed milestone	0.004	0.995	0.000
R65.9 Systemic Inflammatory Response Syndrome, unspecified	0.004	0.995	0.000
R65.3 Systemic Inflammatory Response Syndrome of non-infectious origin with organ failure	0.004	0.995	0.000
R65.2 Systemic Inflammatory Response Syndrome of non-infectious origin without organ failure	0.004	0.995	0.000
R65.1 Systemic Inflammatory Response Syndrome of infectious origin with organ failure	0.004	0.995	0.000
R65.0 Systemic Inflammatory Response Syndrome of infectious origin without organ failure	0.004	0.995	0.000
R73 Elevated blood glucose level	0.005	0.995	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.004	0.995	0.000
I44.5 Left posterior fascicular block	0.004	0.995	0.000
I44.4 Left anterior fascicular block	0.004	0.995	0.000
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
R76 Other abnormal immunological findings in serum	0.004	0.996	0.000
R71 Abnormality of red blood cells	0.004	0.996	0.000
R29.4 Clicking hip	0.004	0.996	0.000
R29.3 Abnormal posture	0.004	0.996	0.000
R29.2 Abnormal reflex	0.004	0.996	0.000
R29.1 Meningismus	0.004	0.996	0.000
R29.0 Tetany	0.004	0.996	0.000
O28 Abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O12.2 Gestational oedema with proteinuria	0.004	0.996	0.000
O12.1 Gestational proteinuria	0.004	0.996	0.000
O12.0 Gestational oedema	0.004	0.996	0.000
O15.9 Eclampsia, unspecified as to time period	0.004	0.996	0.000
O15.2 Eclampsia in the puerperium	0.004	0.996	0.000
O15.1 Eclampsia in labour	0.004	0.996	0.000
O15.0 Eclampsia in pregnancy	0.004	0.996	0.000
O82 Single delivery by Caesarean section	0.004	0.996	0.000
I44.3 Other and unspecified atrioventricular block	0.004	0.996	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.004	0.996	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.004	0.996	0.000
A08.4 Viral intestinal infection, unspecified	0.004	0.996	0.000
O29 Complications of anaesthesia during pregnancy	0.004	0.996	0.000
O22 Venous complications in pregnancy	0.004	0.996	0.000
O25 Malnutrition in pregnancy	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.004	0.996	0.000
E87.6 Hypokalaemia	0.004	0.996	0.000
R27 Other lack of coordination	0.004	0.996	0.000
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.004	0.996	0.000
R77 Other abnormalities of plasma proteins	0.004	0.996	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.004	0.996	0.000
R52.2 Other chronic pain	0.004	0.996	0.000
R26 Abnormalities of gait and mobility	0.004	0.996	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.004	0.996	0.000
R74 Abnormal serum enzyme levels	0.004	0.996	0.000
I44.0 Atrioventricular block, first degree	0.004	0.996	0.000
R26.3 Immobility	0.004	0.996	0.000
I47.0 Reentry ventricular arrhythmia	0.004	0.996	0.000
R73.9 Hyperglycaemia, unspecified	0.004	0.996	0.000
I44.2 Atrioventricular block, complete	0.004	0.996	0.000
O23 Infections of genito-urinary tract in pregnancy	0.004	0.996	0.000
O21 Excessive vomiting in pregnancy	0.004	0.996	0.000
R94 Abnormal results of function studies	0.004	0.996	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.004	0.996	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.004	0.996	0.000
I97.1 Other functional disturbances following cardiac surgery	0.004	0.996	0.000
I97.0 Postcardiotomy syndrome	0.004	0.996	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.004	0.996	0.000
R94.5 Abnormal results of liver function studies	0.004	0.996	0.000
J34 Other disorders of nose and nasal sinuses	0.000	0.996	0.004
K90 Intestinal malabsorption	0.004	0.996	0.000
R47-R49 Symptoms and signs involving speech and voice	0.004	0.996	0.000
R61.1 Generalised hyperhidrosis	0.003	0.996	0.000
R61.0 Localised hyperhidrosis	0.003	0.996	0.000
R76.8 Other specified abnormal immunological findings in serum	0.004	0.996	0.000
O20 Haemorrhage in early pregnancy	0.004	0.996	0.000
R81 Glycosuria	0.003	0.996	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.003	0.996	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.003	0.996	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
I98.0 Cardiovascular syphilis	0.003	0.996	0.000
R73.0 Abnormal glucose tolerance test	0.004	0.996	0.000
I45 Other conduction disorders	0.004	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.996	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.996	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.003	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.003	0.996	0.000
E89.4 Postprocedural ovarian failure	0.003	0.996	0.000
E89.3 Postprocedural hypopituitarism	0.003	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.003	0.996	0.000
R60.1 Generalised oedema	0.003	0.996	0.000
K31 Other diseases of stomach and duodenum	0.004	0.996	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.004	0.996	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations