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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117535546
log Bayes Factor = 19.5942
Chromosome 16   position 65,916,225  (GRCh37) Explore rs117535546 on Ensembl!
Variant rs117535546 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
M70-M79 Other soft tissue disorders
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
R50-R69 General symptoms and signs
0.984 0.016 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.983 0.017 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.983 0.017 0.000
E10-E14 Diabetes mellitus
0.983 0.017 0.000
Chapter XIV Diseases of the genitourinary system
0.982 0.018 0.000
R10 Abdominal and pelvic pain
0.977 0.023 0.000
E11 Non-insulin-dependent diabetes mellitus
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.974 0.026 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
R13 Dysphagia
0.967 0.033 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.967 0.033 0.000
R63 Symptoms and signs concerning food and fluid intake
0.966 0.034 0.000
R29.6 Tendency to fall, not elsewhere classified
0.966 0.034 0.000
R11 Nausea and vomiting
0.965 0.035 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.965 0.035 0.000
N17-N19 Renal failure
0.962 0.038 0.000
Chapter X Diseases of the respiratory system
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.959 0.041 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.959 0.041 0.000
R14 Flatulence and related conditions
0.959 0.041 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.948 0.052 0.000
Z53.9 Procedure not carried out, unspecified reason
0.945 0.055 0.000
R10.3 Pain localised to other parts of lower abdomen
0.943 0.057 0.000
E11.4 With neurological complications
0.943 0.057 0.000
R63.4 Abnormal weight loss
0.940 0.060 0.000
M79.6 Pain in limb
0.936 0.064 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.935 0.065 0.000
I95 Hypotension
0.933 0.067 0.000
N10-N16 Renal tubulo-interstitial diseases
0.932 0.068 0.000
J30-J39 Other diseases of upper respiratory tract
0.930 0.070 0.000
N18 Chronic renal failure
0.926 0.074 0.000
I95.9 Hypotension, unspecified
0.926 0.074 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.926 0.074 0.000
A30-A49 Other bacterial diseases
0.926 0.074 0.000
B95-B98 Bacterial, viral and other infectious agents
0.925 0.075 0.000
D50-D53 Nutritional anaemias
0.925 0.075 0.000
R17 Unspecified jaundice
0.922 0.078 0.000
E11.3 With ophthalmic complications
0.920 0.080 0.000
R47-R49 Symptoms and signs involving speech and voice
0.917 0.083 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.916 0.084 0.000
Chapter VII Diseases of the eye and adnexa
0.912 0.088 0.000
Z45 Adjustment and management of implanted device
0.910 0.090 0.000
D60-D64 Aplastic and other anaemias
0.903 0.097 0.000
J33 Nasal polyp
0.900 0.100 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.896 0.104 0.000
Z49 Care involving dialysis
0.896 0.104 0.000
R12 Heartburn
0.895 0.105 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.894 0.106 0.000
M50-M54 Other dorsopathies
0.894 0.106 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.893 0.107 0.000
M75 Shoulder lesions
0.891 0.109 0.000
D50 Iron deficiency anaemia
0.890 0.110 0.000
N17 Acute renal failure
0.888 0.112 0.000
Z51 Other medical care
0.883 0.117 0.000
E10 Insulin-dependent diabetes mellitus
0.883 0.117 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.881 0.119 0.000
I60-I69 Cerebrovascular diseases
0.878 0.122 0.000
R42 Dizziness and giddiness
0.877 0.123 0.000
N13 Obstructive and reflux uropathy
0.876 0.124 0.000
R27 Other lack of coordination
0.875 0.125 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.875 0.125 0.000
E11.2 With renal complications
0.874 0.126 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.871 0.129 0.000
M79.0 Rheumatism, unspecified
0.869 0.131 0.000
G40-G47 Episodic and paroxysmal disorders
0.866 0.134 0.000
M79.8 Other specified soft tissue disorders
0.865 0.135 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.864 0.136 0.000
R55 Syncope and collapse
0.864 0.136 0.000
R10.2 Pelvic and perineal pain
0.864 0.136 0.000
N25-N29 Other disorders of kidney and ureter
0.864 0.136 0.000
R63.0 Anorexia
0.863 0.137 0.000
A00-A09 Intestinal infectious diseases
0.860 0.140 0.000
Z42 Follow-up care involving plastic surgery
0.858 0.142 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.857 0.143 0.000
R10.0 Acute abdomen
0.856 0.144 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.853 0.147 0.000
J90-J94 Other diseases of pleura
0.852 0.148 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.851 0.149 0.000
R49 Voice disturbances
0.849 0.150 0.000
R45 Symptoms and signs involving emotional state
0.847 0.153 0.000
A49 Bacterial infection of unspecified site
0.845 0.155 0.000
J33.0 Polyp of nasal cavity
0.842 0.158 0.000
Z43 Attention to artificial openings
0.841 0.159 0.000
D50.9 Iron deficiency anaemia, unspecified
0.840 0.160 0.000
M45-M49 Spondylopathies
0.837 0.163 0.000
S50-S59 Injuries to the elbow and forearm
0.837 0.163 0.000
N00-N08 Glomerular diseases
0.835 0.165 0.000
N17.9 Acute renal failure, unspecified
0.835 0.165 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.834 0.166 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.830 0.170 0.000
M54 Dorsalgia
0.828 0.172 0.000
E50-E64 Other nutritional deficiencies
0.827 0.173 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.826 0.174 0.000
R54 Senility
0.825 0.175 0.000
J32 Chronic sinusitis
0.823 0.177 0.000
N18.5 Chronic kidney disease, stage 5
0.822 0.178 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.821 0.179 0.000
W00-W19 Falls
0.817 0.183 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.815 0.185 0.000
L20-L30 Dermatitis and eczema
0.814 0.186 0.000
Z45.2 Adjustment and management of vascular access device
0.813 0.187 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.810 0.190 0.000
R60 Oedema, not elsewhere classified
0.810 0.190 0.000
D64 Other anaemias
0.810 0.190 0.000
G20-G26 Extrapyramidal and movement disorders
0.809 0.191 0.000
O47 False labour
0.807 0.193 0.000
J00-J06 Acute upper respiratory infections
0.804 0.196 0.000
R52 Pain, not elsewhere classified
0.802 0.198 0.000
T86 Failure and rejection of transplanted organs and tissues
0.800 0.200 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.799 0.201 0.000
D80-D89 Certain disorders involving the immune mechanism
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.797 0.203 0.000
D50.8 Other iron deficiency anaemias
0.796 0.204 0.000
Chapter XI Diseases of the digestive system
0.794 0.206 0.000
M79.7 Fibromyalgia
0.793 0.207 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.792 0.208 0.000
Z47 Other orthopaedic follow-up care
0.792 0.208 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.792 0.208 0.000
H30-H36 Disorders of choroid and retina
0.792 0.208 0.000
T92 Sequelae of injuries of upper limb
0.791 0.209 0.000
J34 Other disorders of nose and nasal sinuses
0.791 0.209 0.000
R27.0 Ataxia, unspecified
0.791 0.209 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.791 0.209 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.791 0.209 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.790 0.210 0.000
Q60-Q64 Congenital malformations of the urinary system
0.790 0.210 0.000
Z51.2 Other chemotherapy
0.788 0.212 0.000
M75.0 Adhesive capsulitis of shoulder
0.787 0.213 0.000
E10.9 Without complications
0.787 0.213 0.000
I30-I52 Other forms of heart disease
0.786 0.214 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.785 0.215 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.785 0.215 0.000
I71 Aortic aneurysm and dissection
0.783 0.217 0.000
T79-T79 Certain early complications of trauma
0.782 0.218 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.782 0.218 0.000
Z49.0 Preparatory care for dialysis
0.781 0.219 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.780 0.220 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.780 0.220 0.000
A80-A89 Viral infections of the central nervous system
0.780 0.220 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.779 0.221 0.000
Z60 Problems related to social environment
0.779 0.221 0.000
N18.0 End-stage renal disease
0.778 0.222 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.778 0.222 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.777 0.222 0.000
T90 Sequelae of injuries of head
0.777 0.223 0.000
R49.0 Dysphonia
0.777 0.223 0.000
Z45.8 Adjustment and management of other implanted devices
0.777 0.223 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.775 0.225 0.000
Z41 Procedures for purposes other than remedying health state
0.773 0.226 0.000
M80-M85 Disorders of bone density and structure
0.773 0.227 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.773 0.227 0.000
M71 Other bursopathies
0.773 0.227 0.000
M47 Spondylosis
0.772 0.228 0.000
Z52 Donors of organs and tissues
0.772 0.228 0.000
M60-M63 Disorders of muscles
0.772 0.228 0.000
T87 Complications peculiar to reattachment and amputation
0.771 0.229 0.000
D62 Acute posthaemorrhagic anaemia
0.769 0.231 0.000
M79.66 Pain in limb (Lower leg)
0.769 0.231 0.000
S20-S29 Injuries to the thorax
0.768 0.232 0.000
E11.5 With peripheral circulatory complications
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
G43 Migraine
0.764 0.235 0.000
K70-K77 Diseases of liver
0.764 0.236 0.000
M50 Cervical disk disorders
0.763 0.237 0.000
A40 Streptococcal septicaemia
0.763 0.237 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.761 0.239 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.761 0.239 0.000
W20-W49 Exposure to inanimate mechanical forces
0.761 0.239 0.000
M79.67 Pain in limb (Ankle and foot)
0.761 0.239 0.000
J33.9 Nasal polyp, unspecified
0.759 0.241 0.000
I69 Sequelae of cerebrovascular disease
0.756 0.244 0.000
I74 Arterial embolism and thrombosis
0.755 0.245 0.000
Z57 Occupational exposure to risk-factors
0.754 0.246 0.000
R58 Haemorrhage, not elsewhere classified
0.753 0.247 0.000
A49.0 Staphylococcal infection, unspecified
0.753 0.247 0.000
M79.64 Pain in limb (Hand)
0.753 0.247 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.753 0.247 0.000
I63 Cerebral infarction
0.752 0.248 0.000
E11.6 With other specified complications
0.751 0.249 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.749 0.250 0.000
R45.1 Restlessness and agitation
0.749 0.251 0.000
D52 Folate deficiency anaemia
0.748 0.252 0.000
R40 Somnolence, stupor and coma
0.748 0.252 0.000
E13 Other specified diabetes mellitus
0.748 0.252 0.000
G47 Sleep disorders
0.748 0.252 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
J32.9 Chronic sinusitis, unspecified
0.744 0.256 0.000
M75.5 Bursitis of shoulder
0.744 0.256 0.000
D64.9 Anaemia, unspecified
0.743 0.257 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.743 0.257 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.743 0.257 0.000
Z51.3 Blood transfusion without reported diagnosis
0.742 0.258 0.000
N18.3 Chronic kidney disease, stage 3
0.741 0.259 0.000
I67 Other cerebrovascular diseases
0.741 0.259 0.000
Z49.1 Extracorporeal dialysis
0.740 0.260 0.000
R50 Fever of unknown origin
0.739 0.260 0.000
M79.63 Pain in limb (Forearm)
0.739 0.261 0.000
L29 Pruritus
0.739 0.261 0.000
M79.61 Pain in limb (Shoulder region)
0.738 0.262 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.738 0.262 0.000
K76 Other diseases of liver
0.738 0.262 0.000
B35-B49 Mycoses
0.735 0.265 0.000
H55-H59 Other disorders of eye and adnexa
0.735 0.265 0.000
J60-J70 Lung diseases due to external agents
0.734 0.266 0.000
J33.8 Other polyp of sinus
0.734 0.266 0.000
B25-B34 Other viral diseases
0.733 0.266 0.000
R26 Abnormalities of gait and mobility
0.733 0.267 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.733 0.267 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.731 0.269 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.731 0.269 0.000
O85-O92 Complications predominantly related to the puerperium
0.731 0.269 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.730 0.270 0.000
M79.1 Myalgia
0.730 0.270 0.000
K76.8 Other specified diseases of liver
0.730 0.270 0.000
V10-V19 Pedal cyclist injured in transport accident
0.729 0.271 0.000
R51 Headache
0.729 0.271 0.000
N20-N23 Urolithiasis
0.727 0.273 0.000
N11 Chronic tubulo-interstitial nephritis
0.727 0.273 0.000
Z43.2 Attention to ileostomy
0.726 0.274 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.726 0.274 0.000
R61 Hyperhidrosis
0.726 0.274 0.000
J02 Acute pharyngitis
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.725 0.275 0.000
V40-V49 Car occupant injured in transport accident
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.725 0.275 0.000
N18.2 Chronic kidney disease, stage 2
0.725 0.275 0.000
M54.4 Lumbago with sciatica
0.724 0.276 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.722 0.278 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.722 0.278 0.000
N13.4 Hydroureter
0.720 0.280 0.000
J90 Pleural effusion, not elsewhere classified
0.720 0.280 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.718 0.282 0.000
N18.4 Chronic kidney disease, stage 4
0.718 0.282 0.000
M40-M43 Deforming dorsopathies
0.718 0.282 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.718 0.282 0.000
R10.4 Other and unspecified abdominal pain
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.283 0.000
O80-O84 Delivery
0.716 0.284 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.716 0.284 0.000
Q50-Q56 Congenital malformations of genital organs
0.715 0.285 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.714 0.286 0.000
H36 Retinal disorders in diseases classified elsewhere
0.714 0.286 0.000
M91-M94 Chondropathies
0.713 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.286 0.000
Z54 Convalescence
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.713 0.287 0.000
M47.9 Spondylosis, unspecified
0.712 0.288 0.000
O42 Premature rupture of membranes
0.712 0.288 0.000
I45 Other conduction disorders
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
M54.1 Radiculopathy
0.710 0.290 0.000
G43.9 Migraine, unspecified
0.710 0.290 0.000
M76 Enthesopathies of lower limb, excluding foot
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.710 0.290 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.710 0.290 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.709 0.291 0.000
T93 Sequelae of injuries of lower limb
0.708 0.292 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.708 0.292 0.000
R57 Shock, not elsewhere classified
0.708 0.292 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
O60-O75 Complications of labour and delivery
0.707 0.293 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.706 0.294 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.706 0.294 0.000
B15-B19 Viral hepatitis
0.706 0.294 0.000
Chapter VIII Diseases of the ear and mastoid process
0.706 0.294 0.000
E55 Vitamin D deficiency
0.706 0.294 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.705 0.295 0.000
R62 Lack of expected normal physiological development
0.705 0.295 0.000
R64 Cachexia
0.705 0.295 0.000
R29.4 Clicking hip
0.705 0.295 0.000
R29.3 Abnormal posture
0.705 0.295 0.000
R29.2 Abnormal reflex
0.705 0.295 0.000
R29.1 Meningismus
0.705 0.295 0.000
R29.0 Tetany
0.705 0.295 0.000
M79.9 Soft tissue disorder, unspecified
0.705 0.295 0.000
M79.5 Residual foreign body in soft tissue
0.705 0.295 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.705 0.295 0.000
M79.3 Panniculitis, unspecified
0.705 0.295 0.000
M79.2 Neuralgia and neuritis, unspecified
0.705 0.295 0.000
E12 Malnutrition-related diabetes mellitus
0.705 0.295 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.703 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
N28.8 Other specified disorders of kidney and ureter
0.703 0.297 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.702 0.298 0.000
Z51.1 Chemotherapy session for neoplasm
0.702 0.298 0.000
M75.3 Calcific tendinitis of shoulder
0.701 0.298 0.000
J39 Other diseases of upper respiratory tract
0.701 0.299 0.000
E11.8 With unspecified complications
0.700 0.300 0.000
E11.7 With multiple complications
0.700 0.300 0.000
E11.1 With ketoacidosis
0.700 0.300 0.000
E11.0 With coma
0.700 0.300 0.000
R56 Convulsions, not elsewhere classified
0.699 0.301 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.699 0.301 0.000
A46 Erysipelas
0.699 0.301 0.000
I00-I02 Acute rheumatic fever
0.699 0.301 0.000
S70-S79 Injuries to the hip and thigh
0.699 0.301 0.000
R63.1 Polydipsia
0.699 0.301 0.000
D55-D59 Haemolytic anaemias
0.698 0.302 0.000
G44 Other headache syndromes
0.698 0.302 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.698 0.302 0.000
W07 Fall involving chair
0.698 0.302 0.000
M79.69 Pain in limb (Site unspecified)
0.698 0.302 0.000
I27 Other pulmonary heart diseases
0.698 0.302 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.698 0.302 0.000
M79.60 Pain in limb (Multiple sites)
0.696 0.303 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.696 0.304 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.696 0.304 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.696 0.304 0.000
A49.9 Bacterial infection, unspecified
0.695 0.305 0.000
I67.9 Cerebrovascular disease, unspecified
0.695 0.305 0.000
M65-M68 Disorders of synovium and tendon
0.695 0.305 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.695 0.305 0.000
G30-G32 Other degenerative diseases of the nervous system
0.694 0.305 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.694 0.306 0.000
Z60.2 Living alone
0.694 0.306 0.000
G70-G73 Diseases of myoneural junction and muscle
0.694 0.306 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.694 0.306 0.000
R46 Symptoms and signs involving appearance and behaviour
0.693 0.307 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.693 0.307 0.000
R43 Disturbances of smell and taste
0.693 0.307 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.693 0.307 0.000
R63.5 Abnormal weight gain
0.693 0.307 0.000
R63.3 Feeding difficulties and mismanagement
0.693 0.307 0.000
R63.2 Polyphagia
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.692 0.308 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.692 0.308 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.691 0.309 0.000
S51 Open wound of forearm
0.691 0.309 0.000
R49.8 Other and unspecified voice disturbances
0.690 0.310 0.000
M77 Other enthesopathies
0.689 0.311 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.688 0.312 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.688 0.312 0.000
Y35-Y36 Legal intervention and operations of war
0.688 0.312 0.000
Y10-Y34 Event of undetermined intent
0.688 0.312 0.000
Y00-Y09 Assault
0.688 0.312 0.000
X85-X99 Assault
0.688 0.312 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.688 0.312 0.000
X50-X57 Overexertion, travel and privation
0.688 0.312 0.000
X30-X39 Exposure to forces of nature
0.688 0.312 0.000
X20-X29 Contact with venomous animals and plants
0.688 0.312 0.000
X10-X19 Contact with heat and hot substances
0.688 0.312 0.000
X00-X09 Exposure to smoke, fire and flames
0.688 0.312 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.688 0.312 0.000
W75-W84 Other accidental threats to breathing
0.688 0.312 0.000
W65-W74 Accidental drowning and submersion
0.688 0.312 0.000
W50-W64 Exposure to animate mechanical forces
0.688 0.312 0.000
V98-V99 Other and unspecified transport accidents
0.688 0.312 0.000
V95-V97 Air and space transport accidents
0.688 0.312 0.000
V90-V94 Water transport accidents
0.688 0.312 0.000
V80-V89 Other land transport accidents
0.688 0.312 0.000
V70-V79 Bus occupant injured in transport accident
0.688 0.312 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.688 0.312 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.688 0.312 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.688 0.312 0.000
V01-V09 Pedestrian injured in transport accident
0.688 0.312 0.000
G47.3 Sleep apnoea
0.688 0.312 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.687 0.312 0.000
O44 Placenta praevia
0.687 0.313 0.000
R47 Speech disturbances, not elsewhere classified
0.686 0.314 0.000
H53-H54 Visual disturbances and blindness
0.686 0.314 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.686 0.314 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.685 0.315 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.685 0.315 0.000
R80 Isolated proteinuria
0.684 0.316 0.000
Y40 Systemic antibiotics
0.684 0.316 0.000
L50-L54 Urticaria and erythema
0.683 0.317 0.000
G25 Other extrapyramidal and movement disorders
0.683 0.317 0.000
L29.9 Pruritus, unspecified
0.683 0.317 0.000
E10.3 With ophthalmic complications
0.681 0.319 0.000
G62 Other polyneuropathies
0.681 0.319 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.680 0.320 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.679 0.321 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.678 0.322 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.678 0.322 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.678 0.322 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.678 0.322 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.677 0.323 0.000
O47.0 False labour before 37 completed weeks of gestation
0.677 0.323 0.000
I70 Atherosclerosis
0.677 0.323 0.000
S50 Superficial injury of forearm
0.676 0.324 0.000
I44 Atrioventricular and left bundle-branch block
0.676 0.324 0.000
J91 Pleural effusion in conditions classified elsewhere
0.675 0.325 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.673 0.327 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.672 0.328 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.671 0.328 0.000
M79.68 Pain in limb (Other)
0.671 0.329 0.000
D86 Sarcoidosis
0.671 0.329 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.670 0.330 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.670 0.330 0.000
I95.2 Hypotension due to drugs
0.670 0.330 0.000
E10.4 With neurological complications
0.670 0.330 0.000
J02.9 Acute pharyngitis, unspecified
0.669 0.331 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.669 0.331 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.669 0.331 0.000
I95.8 Other hypotension
0.669 0.331 0.000
I95.0 Idiopathic hypotension
0.669 0.331 0.000
J09-J18 Influenza and pneumonia
0.668 0.332 0.000
I05-I09 Chronic rheumatic heart diseases
0.668 0.332 0.000
G90-G99 Other disorders of the nervous system
0.668 0.332 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.668 0.332 0.000
N15 Other renal tubulo-interstitial diseases
0.668 0.332 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.668 0.332 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.668 0.332 0.000
K90-K93 Other diseases of the digestive system
0.667 0.333 0.000
N28.1 Cyst of kidney, acquired
0.667 0.333 0.000
J37 Chronic laryngitis and laryngotracheitis
0.667 0.333 0.000
Z51.8 Other specified medical care
0.666 0.334 0.000
Q00-Q07 Congenital malformations of the nervous system
0.665 0.335 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.665 0.335 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.664 0.336 0.000
N18.8 Other chronic renal failure
0.664 0.336 0.000
N18.1 Chronic kidney disease, stage 1
0.664 0.336 0.000
L10-L14 Bullous disorders
0.664 0.336 0.000
Z51.9 Medical care, unspecified
0.664 0.336 0.000
N18.9 Chronic renal failure, unspecified
0.664 0.336 0.000
A48 Other bacterial diseases, not elsewhere classified
0.664 0.336 0.000
A44 Bartonellosis
0.664 0.336 0.000
A43 Nocardiosis
0.664 0.336 0.000
A42 Actinomycosis
0.664 0.336 0.000
A39 Meningococcal infection
0.664 0.336 0.000
A37 Whooping cough
0.664 0.336 0.000
A36 Diphtheria
0.664 0.336 0.000
A32 Listeriosis
0.664 0.336 0.000
A31 Infection due to other mycobacteria
0.664 0.336 0.000
A30 Leprosy [Hansen's disease]
0.664 0.336 0.000
A38 Scarlet fever
0.664 0.336 0.000
A35 Other tetanus
0.664 0.336 0.000
A34 Obstetrical tetanus
0.664 0.336 0.000
A33 Tetanus neonatorum
0.664 0.336 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.663 0.337 0.000
D53 Other nutritional anaemias
0.663 0.337 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.662 0.338 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.661 0.338 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.338 0.000
R60.0 Localised oedema
0.661 0.339 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.661 0.339 0.000
Z71.8 Other specified counselling
0.660 0.340 0.000
K75 Other inflammatory liver diseases
0.660 0.340 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.660 0.340 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.660 0.340 0.000
A08 Viral and other specified intestinal infections
0.659 0.341 0.000
I99 Other and unspecified disorders of circulatory system
0.659 0.341 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.658 0.342 0.000
H36.0 Diabetic retinopathy
0.658 0.342 0.000
T92.0 Sequelae of open wound of upper limb
0.657 0.342 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.657 0.343 0.000
K65-K67 Diseases of peritoneum
0.657 0.343 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q80-Q89 Other congenital malformations
0.657 0.343 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.657 0.343 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
T98 Sequelae of other and unspecified effects of external causes
0.657 0.343 0.000
T95 Sequelae of burns, corrosions and frostbite
0.657 0.343 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.657 0.343 0.000
T91 Sequelae of injuries of neck and trunk
0.657 0.343 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.657 0.343 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.657 0.343 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.657 0.343 0.000
M79.79 Fibromyalgia (Site unspecified)
0.657 0.343 0.000
Q63 Other congenital malformations of kidney
0.656 0.343 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.655 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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