TreeWAS – Variant ID: rs11756438

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H11.0 Pterygium	0.023	0.977	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.984	0.016
E11.3 With ophthalmic complications	0.016	0.984	0.000
H66.9 Otitis media, unspecified	0.000	0.985	0.015
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.986	0.014
H11.9 Disorder of conjunctiva, unspecified	0.013	0.987	0.000
H11 Other disorders of conjunctiva	0.013	0.987	0.000
R73.9 Hyperglycaemia, unspecified	0.013	0.987	0.000
I63.8 Other cerebral infarction	0.000	0.988	0.012
E10.4 With neurological complications	0.011	0.989	0.000
I63 Cerebral infarction	0.000	0.989	0.011
H11.1 Conjunctival degenerations and deposits	0.011	0.989	0.000
E10.3 With ophthalmic complications	0.011	0.989	0.000
E10 Insulin-dependent diabetes mellitus	0.011	0.989	0.000
E11.2 With renal complications	0.010	0.990	0.000
E11 Non-insulin-dependent diabetes mellitus	0.010	0.990	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.990	0.010
E10.0 With coma	0.010	0.990	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.990	0.009
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.991	0.009
C48.2 Peritoneum, unspecified	0.000	0.991	0.009
G55.3 Nerve root and plexus compressions in other dorsopathies	0.009	0.991	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.991	0.009
O80.0 Spontaneous vertex delivery	0.000	0.991	0.009
E10.5 With peripheral circulatory complications	0.008	0.991	0.000
E10.6 With other specified complications	0.008	0.992	0.000
E11.8 With unspecified complications	0.008	0.992	0.000
R00.2 Palpitations	0.000	0.992	0.008
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.008	0.992	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.992	0.008
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.992	0.008
E10-E14 Diabetes mellitus	0.008	0.992	0.000
E11.4 With neurological complications	0.008	0.992	0.000
H10-H13 Disorders of conjunctiva	0.008	0.992	0.000
E10.2 With renal complications	0.008	0.992	0.000
E10.7 With multiple complications	0.008	0.992	0.000
C43 Malignant melanoma of skin	0.000	0.992	0.008
H11.2 Conjunctival scars	0.008	0.992	0.000
E11.5 With peripheral circulatory complications	0.008	0.992	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.992	0.008
E11.7 With multiple complications	0.007	0.992	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.993	0.007
H10 Conjunctivitis	0.007	0.993	0.000
H11.8 Other specified disorders of conjunctiva	0.007	0.993	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.007	0.993	0.000
E10.8 With unspecified complications	0.007	0.993	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.993	0.007
C44.3 Skin of other and unspecified parts of face	0.000	0.993	0.007
R73 Elevated blood glucose level	0.007	0.993	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.006	0.993	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.994	0.006
H36.0 Diabetic retinopathy	0.006	0.994	0.000
E12 Malnutrition-related diabetes mellitus	0.006	0.994	0.000
H10.1 Acute atopic conjunctivitis	0.006	0.994	0.000
E11.6 With other specified complications	0.006	0.994	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.994	0.006
C43.0 Malignant melanoma of lip	0.000	0.994	0.006
H10.3 Acute conjunctivitis, unspecified	0.006	0.994	0.000
H10.8 Other conjunctivitis	0.006	0.994	0.000
S50 Superficial injury of forearm	0.000	0.994	0.006
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.006	0.994	0.000
K07.6 Temporomandibular joint disorders	0.006	0.994	0.000
R73.0 Abnormal glucose tolerance test	0.006	0.994	0.000
H10.9 Conjunctivitis, unspecified	0.006	0.994	0.000
H11.3 Conjunctival haemorrhage	0.005	0.994	0.000
H10.4 Chronic conjunctivitis	0.005	0.994	0.000
H10.5 Blepharoconjunctivitis	0.005	0.994	0.000
H10.2 Other acute conjunctivitis	0.005	0.994	0.000
H10.0 Mucopurulent conjunctivitis	0.005	0.994	0.000
S50.8 Other superficial injuries of forearm	0.000	0.994	0.005
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.995	0.005
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H13.3 Ocular pemphigoid	0.005	0.995	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.000	0.995	0.005
E10.1 With ketoacidosis	0.005	0.995	0.000
M95.0 Acquired deformity of nose	0.000	0.995	0.005
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.005	0.995	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.005	0.995	0.000
H13.0 Filarial infection of conjunctiva	0.005	0.995	0.000
E14 Unspecified diabetes mellitus	0.005	0.995	0.000
E13 Other specified diabetes mellitus	0.005	0.995	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.995	0.005
E11.1 With ketoacidosis	0.005	0.995	0.000
E14.2 Withrenal complications	0.005	0.995	0.000
E12.9 Without complications	0.005	0.995	0.000
E12.8 With unspecified complications	0.005	0.995	0.000
E12.7 With multiple complications	0.005	0.995	0.000
E12.6 With other specified complications	0.005	0.995	0.000
E12.5 With peripheral circulatory complications	0.005	0.995	0.000
E12.4 With neurological complications	0.005	0.995	0.000
E12.3 With ophthalmic complications	0.005	0.995	0.000
E12.2 With renal complications	0.005	0.995	0.000
E12.1 With ketoacidosis	0.005	0.995	0.000
E12.0 With coma	0.005	0.995	0.000
E14.1 With ketoacidosis	0.005	0.995	0.000
S50.0 Contusion of elbow	0.000	0.995	0.005
C43.5 Malignant melanoma of trunk	0.000	0.995	0.005
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.996	0.004
M79.18 Myalgia (Other)	0.000	0.996	0.004
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.996	0.004
S80.9 Superficial injury of lower leg, unspecified	0.000	0.996	0.004
K07.2 Anomalies of dental arch relationship	0.004	0.996	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.996	0.004
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
S50.7 Multiple superficial injuries of forearm	0.000	0.996	0.004
E14.4 With neurological complications	0.004	0.996	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.996	0.004
K07 Dentofacial anomalies [including malocclusion]	0.004	0.996	0.000
E14.7 With multiple complications	0.004	0.996	0.000
E14.0 With coma	0.004	0.996	0.000
E13.8 With unspecified complications	0.004	0.996	0.000
E13.7 With multiple complications	0.004	0.996	0.000
E13.6 With other specified complications	0.004	0.996	0.000
E13.5 With peripheral circulatory complications	0.004	0.996	0.000
E13.4 With neurological complications	0.004	0.996	0.000
E13.2 With renal complications	0.004	0.996	0.000
E13.1 With ketoacidosis	0.004	0.996	0.000
E13.0 With coma	0.004	0.996	0.000
E14.6 With other specified complications	0.004	0.996	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.996	0.004
E11.0 With coma	0.003	0.996	0.001
W07.0 Home	0.004	0.996	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.996	0.004
Z81 Family history of mental and behavioural disorders	0.000	0.996	0.004
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.996	0.004
E13.3 With ophthalmic complications	0.003	0.996	0.000
M79.1 Myalgia	0.000	0.996	0.004
E14.5 With peripheral circulatory complications	0.003	0.996	0.000
C48.0 Retroperitoneum	0.000	0.997	0.003
M79.19 Myalgia (Site unspecified)	0.000	0.997	0.003
K07.4 Malocclusion, unspecified	0.003	0.997	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.997	0.003
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.997	0.003
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.997	0.003
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.003	0.997	0.000
Z81.1 Family history of alcohol abuse	0.000	0.997	0.003
D06.9 Cervix, unspecified	0.000	0.997	0.003
K07.9 Dentofacial anomaly, unspecified	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.000	0.997	0.003
E14.8 With unspecified complications	0.003	0.997	0.000
S82.50 Fracture of medial malleolus (closed)	0.003	0.997	0.000
K07.8 Other dentofacial anomalies	0.003	0.997	0.000
K07.5 Dentofacial functional abnormalities	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.997	0.003
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
Z81.4 Family history of other substance abuse	0.000	0.997	0.003
Z81.3 Family history of other psychoactive substance abuse	0.000	0.997	0.003
Z81.2 Family history of tobacco abuse	0.000	0.997	0.003
Z81.0 Family history of mental retardation	0.000	0.997	0.003
M79.17 Myalgia (Ankle and foot)	0.000	0.997	0.003
M79.14 Myalgia (Hand)	0.000	0.997	0.003
M79.13 Myalgia (Forearm)	0.000	0.997	0.003
M79.12 Myalgia (Upper arm)	0.000	0.997	0.003
D12.5 Sigmoid colon	0.000	0.997	0.003
C44.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
K07.3 Anomalies of tooth position	0.003	0.997	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.997	0.003
M79.16 Myalgia (Lower leg)	0.000	0.997	0.003
G11 Hereditary ataxia	0.000	0.997	0.003
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
G11.4 Hereditary spastic paraplegia	0.000	0.997	0.003
M62.8 Other specified disorders of muscle	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
E13.9 Without complications	0.003	0.997	0.000
O80 Single spontaneous delivery	0.000	0.997	0.003
C48.1 Specified parts of peritoneum	0.000	0.997	0.002
K07.0 Major anomalies of jaw size	0.002	0.997	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.003	0.997	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
W07 Fall involving chair	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
A40.9 Streptococcal septicaemia, unspecified	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.998	0.002
G11.1 Early-onset cerebellar ataxia	0.000	0.998	0.002
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
G11.8 Other hereditary ataxias	0.000	0.998	0.002
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.998	0.002
G11.2 Late-onset cerebellar ataxia	0.000	0.998	0.002
G11.0 Congenital nonprogressive ataxia	0.000	0.998	0.002
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.998	0.002
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.998	0.002
O80.1 Spontaneous breech delivery	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.998	0.002
R00 Abnormalities of heart beat	0.000	0.998	0.002
W07.8 Other specified place	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
W07.9 Unspecified place	0.002	0.998	0.000
W07.5 Trade and service area	0.002	0.998	0.000
R00.0 Tachycardia, unspecified	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.998	0.002
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.000	0.998	0.002
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
H66 Suppurative and unspecified otitis media	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.000	0.998	0.002
R32 Unspecified urinary incontinence	0.000	0.998	0.002
O80.8 Other single spontaneous delivery	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
W07.2 School, other institution and public administrative area	0.002	0.998	0.000
W07.7 Farm	0.002	0.998	0.000
W07.6 Industrial and construction area	0.002	0.998	0.000
W07.4 Street and highway	0.002	0.998	0.000
W07.3 Sports and athletics area	0.002	0.998	0.000
W07.1 Residential institution	0.002	0.998	0.000
Z43.0 Attention to tracheostomy	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
D26.0 Cervix uteri	0.000	0.998	0.002
W13.9 Unspecified place	0.000	0.998	0.002
G44.2 Tension-type headache	0.002	0.998	0.000
M24.0 Loose body in joint	0.000	0.998	0.002
O81.0 Low forceps delivery	0.000	0.998	0.002
A40 Streptococcal septicaemia	0.002	0.998	0.000
M83.80 Other adult osteomalacia (Multiple sites)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
Z49.0 Preparatory care for dialysis	0.002	0.998	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.002	0.998	0.000
R00.1 Bradycardia, unspecified	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
C44 Other malignant neoplasms of skin	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.998	0.000
A40.1 Septicaemia due to streptococcus, group B	0.002	0.998	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.002	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.06 Loose body in joint-Lower leg	0.000	0.998	0.002
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.002
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.002	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.002	0.998	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.998	0.000
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.001	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
B27.9 Infectious mononucleosis, unspecified	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
Z99.2 Dependence on renal dialysis	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
G12.2 Motor neuron disease	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.000	0.998	0.001
M24.08 Loose body in joint (Other)	0.000	0.998	0.001
M24.00 Loose body in joint (Multiple sites)	0.000	0.998	0.001
M62.88 Other specified disorders of muscle (Other)	0.000	0.998	0.001
A40.2 Septicaemia due to streptococcus, group D	0.001	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.000	0.998	0.002
V49.9 Car occupant [any] injured in unspecified traffic accident	0.000	0.998	0.002
M83 Adult osteomalacia	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.998	0.000
H66.0 Acute suppurative otitis media	0.000	0.998	0.001
M24.01 Loose body in joint (Shoulder region)	0.000	0.998	0.002
C44.8 Overlapping lesion of skin	0.000	0.998	0.001
H26.8 Other specified cataract	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.000	0.998	0.001
O02.1 Missed abortion	0.000	0.998	0.002
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.002	0.998	0.000
G83.4 Cauda equina syndrome	0.000	0.998	0.002
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.998	0.001
O81.2 Mid-cavity forceps with rotation	0.000	0.998	0.001
O81.1 Mid-cavity forceps delivery	0.000	0.998	0.001
M62 Other disorders of muscle	0.000	0.998	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.001
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.998	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.998	0.002
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.998	0.001
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.998	0.001
M95.5 Acquired deformity of pelvis	0.000	0.998	0.001
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.001
M83.89 Other adult osteomalacia (Site unspecified)	0.001	0.998	0.000
M83.88 Other adult osteomalacia (Other)	0.001	0.998	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.001	0.998	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.001	0.998	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.001	0.998	0.000
M83.84 Other adult osteomalacia (Hand)	0.001	0.998	0.000
M83.83 Other adult osteomalacia (Forearm)	0.001	0.998	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.001	0.998	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.001	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.001	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.998	0.000
C16.4 Pylorus	0.001	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.001
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.001	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.001
M83.1 Senile osteomalacia	0.001	0.998	0.000
M95.3 Acquired deformity of neck	0.000	0.998	0.001
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.998	0.001
E78.8 Other disorders of lipoprotein metabolism	0.001	0.999	0.000
M95.1 Cauliflower ear	0.000	0.999	0.001
M81 Osteoporosis without pathological fracture	0.001	0.999	0.000
M24.03 Loose body in joint (Forearm)	0.000	0.999	0.001
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.999	0.000
S93.1 Dislocation of toe(s)	0.000	0.999	0.001
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.999	0.001
M80-M85 Disorders of bone density and structure	0.001	0.999	0.000
A69.9 Spirochaetal infection, unspecified	0.001	0.999	0.000
C16.8 Overlapping lesion of stomach	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.000	0.999	0.001
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.000	0.999	0.001
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.000	0.999	0.001
C16.0 Cardia	0.001	0.999	0.000
K26.5 Chronic or unspecified with perforation	0.000	0.999	0.001
M51.4 Schmorl's nodes	0.000	0.999	0.001
M62.1 Other rupture of muscle (nontraumatic)	0.000	0.999	0.001
M83.9 Adult osteomalacia, unspecified	0.001	0.999	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.999	0.000
M83.4 Aluminum bone disease	0.001	0.999	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.999	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.999	0.000
M83.0 Puerperal osteomalacia	0.001	0.999	0.000
Q38.7 Pharyngeal pouch	0.001	0.999	0.000
Q38.1 Ankyloglossia	0.001	0.999	0.000
Q79.0 Congenital diaphragmatic hernia	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M83.12 Senile osteomalacia (Upper arm)	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.999	0.001
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.000	0.999	0.001
C44.0 Skin of lip	0.000	0.999	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.999	0.000
M62.3 Immobility syndrome (paraplegic)	0.000	0.999	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.001	0.999	0.000
Q12.0 Congenital cataract	0.001	0.999	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.999	0.001
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.000	0.999	0.001
C16.2 Body of stomach	0.001	0.999	0.000
O81.3 Other and unspecified forceps delivery	0.000	0.999	0.001
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
W55.0 Home	0.000	0.999	0.001
O80-O84 Delivery	0.000	0.999	0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.000	0.999	0.001
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.999	0.001
A40.0 Septicaemia due to streptococcus, group A	0.001	0.999	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.999	0.001
G83.1 Monoplegia of lower limb	0.000	0.999	0.001
M62.9 Disorder of muscle, unspecified	0.000	0.999	0.001
M81.8 Other osteoporosis	0.001	0.999	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.999	0.001
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.001	0.999	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.001	0.999	0.000
M83.18 Senile osteomalacia (Other)	0.001	0.999	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.001	0.999	0.000
M83.16 Senile osteomalacia (Lower leg)	0.001	0.999	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.001	0.999	0.000
M83.14 Senile osteomalacia (Hand)	0.001	0.999	0.000
M83.13 Senile osteomalacia (Forearm)	0.001	0.999	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.001	0.999	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.001	0.999	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.999	0.001
K35.9 Acute appendicitis, unspecified	0.001	0.999	0.000
W60.0 Home	0.000	0.999	0.001
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.999	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.999	0.001
M62.4 Contracture of muscle	0.000	0.999	0.001
M62.2 Ischaemic infarction of muscle	0.000	0.999	0.001
M62.0 Diastasis of muscle	0.000	0.999	0.001
M81.6 Localised osteoporosis [Lequesne]	0.001	0.999	0.000
M81.5 Idiopathic osteoporosis	0.001	0.999	0.000
M81.1 Postoophorectomy osteoporosis	0.001	0.999	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.001	0.999	0.000
Q79.5 Other congenital malformations of abdominal wall	0.001	0.999	0.000
Q79.4 Prune belly syndrome	0.001	0.999	0.000
Q79.3 Gastroschisis	0.001	0.999	0.000
Q79.2 Exomphalos	0.001	0.999	0.000
Q79.1 Other congenital malformations of diaphragm	0.001	0.999	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.999	0.001
C46 Kaposi's sarcoma	0.000	0.999	0.001
J80 Adult respiratory distress syndrome	0.001	0.999	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.001	0.999	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.999	0.001
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
M14.6 Neuropathic arthropathy	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
X49.9 Unspecified place	0.000	0.999	0.001
J82 Pulmonary eosinophilia, not elsewhere classified	0.001	0.999	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.000	0.999	0.001
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.000	0.999	0.001
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.000	0.999	0.001
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.000	0.999	0.001
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations