TreeWAS – Variant ID: rs117620493

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.996	0.004	0.000
Chapter XXI Factors influencing health status and contact with health services	0.996	0.004	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.995	0.005	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.987	0.013	0.000
I25.2 Old myocardial infarction	0.984	0.016	0.000
M45-M49 Spondylopathies	0.983	0.017	0.000
I25.1 Atherosclerotic heart disease	0.982	0.018	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.981	0.019	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.981	0.019	0.000
R00 Abnormalities of heart beat	0.975	0.025	0.000
I50 Heart failure	0.975	0.025	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.968	0.032	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.964	0.036	0.000
Z86 Personal history of certain other diseases	0.964	0.036	0.000
M47 Spondylosis	0.961	0.039	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.960	0.040	0.000
R50-R69 General symptoms and signs	0.957	0.043	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.957	0.043	0.000
M20-M25 Other joint disorders	0.955	0.045	0.000
E70-E90 Metabolic disorders	0.954	0.046	0.000
I51 Complications and ill-defined descriptions of heart disease	0.953	0.047	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.949	0.051	0.000
R10 Abdominal and pelvic pain	0.949	0.051	0.000
M20 Acquired deformities of fingers and toes	0.943	0.057	0.000
Chapter I Certain infectious and parasitic diseases	0.941	0.059	0.000
R00.2 Palpitations	0.941	0.059	0.000
Chapter XIV Diseases of the genitourinary system	0.929	0.071	0.000
R10.1 Pain localised to upper abdomen	0.924	0.076	0.000
S60-S69 Injuries to the wrist and hand	0.923	0.077	0.000
I74 Arterial embolism and thrombosis	0.921	0.079	0.000
R06 Abnormalities of breathing	0.920	0.080	0.000
N17-N19 Renal failure	0.913	0.087	0.000
I34 Nonrheumatic mitral valve disorders	0.913	0.087	0.000
E86 Volume depletion	0.905	0.095	0.000
I38 Endocarditis, valve unspecified	0.902	0.098	0.000
M47.9 Spondylosis, unspecified	0.901	0.099	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.900	0.100	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.899	0.101	0.000
R52 Pain, not elsewhere classified	0.895	0.105	0.000
I50.9 Heart failure, unspecified	0.892	0.108	0.000
R59 Enlarged lymph nodes	0.892	0.108	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.892	0.108	0.000
R10.2 Pelvic and perineal pain	0.891	0.109	0.000
R06.0 Dyspnoea	0.886	0.114	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.884	0.116	0.000
Chapter XX External causes of morbidity and mortality	0.884	0.116	0.000
Z93 Artificial opening status	0.882	0.118	0.000
I24 Other acute ischaemic heart diseases	0.877	0.123	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.875	0.125	0.000
I50.0 Congestive heart failure	0.875	0.125	0.000
S40-S49 Injuries to the shoulder and upper arm	0.873	0.127	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.872	0.128	0.000
R00.0 Tachycardia, unspecified	0.869	0.131	0.000
M47.8 Other spondylosis	0.866	0.134	0.000
I34.0 Mitral (valve) insufficiency	0.865	0.135	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.865	0.135	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.861	0.139	0.000
R60 Oedema, not elsewhere classified	0.860	0.140	0.000
R47-R49 Symptoms and signs involving speech and voice	0.858	0.142	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.857	0.143	0.000
R05 Cough	0.855	0.145	0.000
I47 Paroxysmal tachycardia	0.854	0.146	0.000
N17 Acute renal failure	0.854	0.146	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.852	0.148	0.000
N25-N29 Other disorders of kidney and ureter	0.852	0.148	0.000
I73 Other peripheral vascular diseases	0.851	0.149	0.000
I72 Other aneurysm	0.850	0.150	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.848	0.152	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.844	0.156	0.000
M20.3 Other deformity of hallux (acquired)	0.843	0.157	0.000
E87.7 Fluid overload	0.840	0.160	0.000
Z93.2 Ileostomy status	0.840	0.160	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.838	0.162	0.000
I51.8 Other ill-defined heart diseases	0.838	0.162	0.000
M20.4 Other hammer toe(s) (acquired)	0.837	0.163	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.837	0.163	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.833	0.167	0.000
I20 Angina pectoris	0.833	0.167	0.000
Z86.4 Personal history of psychoactive substance abuse	0.833	0.167	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.831	0.169	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.827	0.173	0.000
I21 Acute myocardial infarction	0.825	0.175	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.825	0.175	0.000
I84 Haemorrhoids	0.825	0.175	0.000
R52.1 Chronic intractable pain	0.824	0.176	0.000
I51.9 Heart disease, unspecified	0.823	0.177	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.822	0.178	0.000
M20.0 Deformity of finger(s)	0.821	0.179	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.820	0.180	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.820	0.180	0.000
A00-A09 Intestinal infectious diseases	0.819	0.181	0.000
A30-A49 Other bacterial diseases	0.817	0.183	0.000
I60-I69 Cerebrovascular diseases	0.816	0.183	0.000
Chapter V Mental and behavioural disorders	0.816	0.184	0.000
M46 Other inflammatory spondylopathies	0.814	0.185	0.000
S80-S89 Injuries to the knee and lower leg	0.813	0.187	0.000
I45 Other conduction disorders	0.812	0.188	0.000
N17.9 Acute renal failure, unspecified	0.812	0.188	0.000
N19 Unspecified renal failure	0.811	0.189	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.809	0.191	0.000
R63 Symptoms and signs concerning food and fluid intake	0.808	0.192	0.000
I50.1 Left ventricular failure	0.806	0.194	0.000
R61 Hyperhidrosis	0.804	0.196	0.000
R59.0 Localised enlarged lymph nodes	0.802	0.198	0.000
I49 Other cardiac arrhythmias	0.802	0.198	0.000
I46 Cardiac arrest	0.801	0.198	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.801	0.199	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.801	0.199	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.798	0.202	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.797	0.203	0.000
M80-M85 Disorders of bone density and structure	0.797	0.203	0.000
I84.9 Unspecified haemorrhoids without complication	0.797	0.203	0.000
Z83 Family history of other specific disorders	0.797	0.203	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.796	0.204	0.000
I51.7 Cardiomegaly	0.793	0.207	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.793	0.207	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.792	0.208	0.000
R30-R39 Symptoms and signs involving the urinary system	0.791	0.209	0.000
S67 Crushing injury of wrist and hand	0.790	0.210	0.000
Z86.0 Personal history of other neoplasms	0.789	0.211	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.789	0.211	0.000
I37 Pulmonary valve disorders	0.788	0.212	0.000
N18 Chronic renal failure	0.785	0.215	0.000
Z95.0 Presence of cardiac pacemaker	0.784	0.216	0.000
R53 Malaise and fatigue	0.783	0.217	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.782	0.217	0.000
Z57 Occupational exposure to risk-factors	0.781	0.219	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.781	0.219	0.000
I24.8 Other forms of acute ischaemic heart disease	0.780	0.220	0.000
Z04 Examination and observation for other reasons	0.780	0.220	0.000
N10-N16 Renal tubulo-interstitial diseases	0.779	0.221	0.000
Z99.2 Dependence on renal dialysis	0.779	0.221	0.000
M49 Spondylopathies in diseases classified elsewhere	0.778	0.222	0.000
M86-M90 Other osteopathies	0.776	0.224	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.776	0.224	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.774	0.226	0.000
I35 Nonrheumatic aortic valve disorders	0.774	0.226	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.773	0.227	0.000
W20-W49 Exposure to inanimate mechanical forces	0.773	0.227	0.000
M31 Other necrotising vasculopathies	0.770	0.229	0.000
I44 Atrioventricular and left bundle-branch block	0.767	0.233	0.000
I73.9 Peripheral vascular disease, unspecified	0.766	0.234	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.765	0.235	0.000
M22 Disorders of patella	0.765	0.235	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.763	0.236	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.762	0.238	0.000
E83 Disorders of mineral metabolism	0.762	0.238	0.000
I42 Cardiomyopathy	0.760	0.240	0.000
Z95.1 Presence of aortocoronary bypass graft	0.759	0.241	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.759	0.241	0.000
I78 Diseases of capillaries	0.757	0.242	0.000
R68 Other general symptoms and signs	0.757	0.243	0.000
R02 Gangrene, not elsewhere classified	0.757	0.243	0.000
E50-E64 Other nutritional deficiencies	0.755	0.245	0.000
E87.2 Acidosis	0.754	0.246	0.000
R59.1 Generalised enlarged lymph nodes	0.753	0.247	0.000
I70 Atherosclerosis	0.752	0.248	0.000
E88 Other metabolic disorders	0.751	0.249	0.000
I47.2 Ventricular tachycardia	0.750	0.250	0.000
M70-M79 Other soft tissue disorders	0.750	0.250	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.749	0.251	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.748	0.252	0.000
M47.86 Other spondylosis (Lumbar region)	0.746	0.254	0.000
M20.5 Other deformities of toe(s) (acquired)	0.745	0.255	0.000
R60.0 Localised oedema	0.745	0.255	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.744	0.256	0.000
R63.0 Anorexia	0.743	0.257	0.000
R35 Polyuria	0.742	0.258	0.000
S70-S79 Injuries to the hip and thigh	0.741	0.258	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.741	0.259	0.000
R15 Faecal incontinence	0.740	0.260	0.000
Z13 Special screening examination for other diseases and disorders	0.740	0.260	0.000
B35-B49 Mycoses	0.740	0.260	0.000
I30 Acute pericarditis	0.740	0.260	0.000
R47 Speech disturbances, not elsewhere classified	0.740	0.260	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.739	0.261	0.000
M91-M94 Chondropathies	0.739	0.261	0.000
I74.5 Embolism and thrombosis of iliac artery	0.739	0.261	0.000
I71 Aortic aneurysm and dissection	0.738	0.262	0.000
T86 Failure and rejection of transplanted organs and tissues	0.737	0.263	0.000
M47.1 Other spondylosis with myelopathy	0.736	0.263	0.000
Chapter XXII Codes for special purposes	0.735	0.265	0.000
B95-B98 Bacterial, viral and other infectious agents	0.734	0.266	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.733	0.266	0.000
I77 Other disorders of arteries and arterioles	0.732	0.268	0.000
R57 Shock, not elsewhere classified	0.732	0.268	0.000
S20-S29 Injuries to the thorax	0.731	0.269	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.731	0.269	0.000
Z92 Personal history of medical treatment	0.730	0.270	0.000
I10-I15 Hypertensive diseases	0.730	0.270	0.000
N28.1 Cyst of kidney, acquired	0.729	0.271	0.000
S64 Injury of nerves at wrist and hand level	0.728	0.271	0.000
R52.0 Acute pain	0.728	0.272	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.726	0.274	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.725	0.275	0.000
M47.2 Other spondylosis with radiculopathy	0.724	0.276	0.000
L20-L30 Dermatitis and eczema	0.724	0.276	0.000
I33 Acute and subacute endocarditis	0.723	0.276	0.000
M48 Other spondylopathies	0.723	0.277	0.000
S90-S99 Injuries to the ankle and foot	0.723	0.277	0.000
I86 Varicose veins of other sites	0.722	0.277	0.000
M34 Systemic sclerosis	0.721	0.278	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.721	0.278	0.000
Chapter X Diseases of the respiratory system	0.721	0.279	0.000
I72.8 Aneurysm of other specified arteries	0.720	0.280	0.000
T43.2 Other and unspecified antidepressants	0.720	0.280	0.000
Z89 Acquired absence of limb	0.719	0.281	0.000
N13 Obstructive and reflux uropathy	0.719	0.281	0.000
M20.2 Hallux rigidus	0.719	0.281	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.5 Ischaemic cardiomyopathy	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.717	0.283	0.000
I25.3 Aneurysm of heart	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283	0.000
I48 Atrial fibrillation and flutter	0.717	0.283	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283	0.000
I41 Myocarditis in diseases classified elsewhere	0.717	0.283	0.000
I40 Acute myocarditis	0.717	0.283	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283	0.000
I36 Nonrheumatic tricuspid valve disorders	0.717	0.283	0.000
I32 Pericarditis in diseases classified elsewhere	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.717	0.283	0.000
T79-T79 Certain early complications of trauma	0.716	0.283	0.000
T33-T35 Frostbite	0.716	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.283	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.283	0.000
S10-S19 Injuries to the neck	0.716	0.283	0.000
E20-E35 Disorders of other endocrine glands	0.715	0.285	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.714	0.286	0.000
M60-M63 Disorders of muscles	0.713	0.287	0.000
M00-M03 Infectious arthropathies	0.713	0.287	0.000
Z99.3 Dependence on wheelchair	0.713	0.287	0.000
R60.9 Oedema, unspecified	0.713	0.287	0.000
R10.0 Acute abdomen	0.713	0.287	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.713	0.287	0.000
M21 Other acquired deformities of limbs	0.712	0.288	0.000
I05-I09 Chronic rheumatic heart diseases	0.711	0.289	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.710	0.290	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.710	0.290	0.000
E89.0 Postprocedural hypothyroidism	0.709	0.291	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.709	0.291	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.708	0.291	0.000
R06.2 Wheezing	0.708	0.292	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.708	0.292	0.000
R11 Nausea and vomiting	0.706	0.294	0.000
I22 Subsequent myocardial infarction	0.705	0.295	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.705	0.295	0.000
R39 Other symptoms and signs involving the urinary system	0.705	0.295	0.000
M45 Ankylosing spondylitis	0.704	0.295	0.000
M05-M14 Inflammatory polyarthropathies	0.704	0.296	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.703	0.297	0.000
Z84 Family history of other conditions	0.703	0.297	0.000
Z81 Family history of mental and behavioural disorders	0.703	0.297	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.703	0.297	0.000
R10.3 Pain localised to other parts of lower abdomen	0.703	0.297	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.702	0.297	0.000
M20.1 Hallux valgus (acquired)	0.702	0.298	0.000
Z83.5 Family history of eye and ear disorders	0.702	0.298	0.000
T42.4 Benzodiazepines	0.702	0.298	0.000
R23 Other skin changes	0.701	0.299	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.700	0.300	0.000
I87 Other disorders of veins	0.700	0.300	0.000
N28.8 Other specified disorders of kidney and ureter	0.699	0.301	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.698	0.302	0.000
I20.9 Angina pectoris, unspecified	0.698	0.302	0.000
I82 Other venous embolism and thrombosis	0.697	0.303	0.000
Z94 Transplanted organ and tissue status	0.697	0.303	0.000
I20.8 Other forms of angina pectoris	0.696	0.304	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.696	0.304	0.000
F60-F69 Disorders of adult personality and behaviour	0.696	0.304	0.000
Y00-Y09 Assault	0.695	0.305	0.000
R61.9 Hyperhidrosis, unspecified	0.695	0.305	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.694	0.306	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.694	0.306	0.000
E40-E46 Malnutrition	0.694	0.306	0.000
R00.1 Bradycardia, unspecified	0.694	0.306	0.000
I84.8 Unspecified haemorrhoids with other complications	0.692	0.308	0.000
M80 Osteoporosis with pathological fracture	0.692	0.308	0.000
S40 Superficial injury of shoulder and upper arm	0.691	0.309	0.000
N20-N23 Urolithiasis	0.691	0.309	0.000
R06.4 Hyperventilation	0.691	0.309	0.000
T87 Complications peculiar to reattachment and amputation	0.691	0.309	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.691	0.309	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.691	0.309	0.000
N40-N51 Diseases of male genital organs	0.690	0.310	0.000
Z98 Other postsurgical states	0.690	0.310	0.000
Z93.6 Other artificial openings of urinary tract status	0.690	0.310	0.000
I60 Subarachnoid haemorrhage	0.690	0.310	0.000
Z72 Problems related to lifestyle	0.689	0.311	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.689	0.311	0.000
Z95.4 Presence of other heart-valve replacement	0.689	0.311	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.688	0.311	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.688	0.312	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.688	0.312	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.688	0.312	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.688	0.312	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.688	0.312	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.688	0.312	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.688	0.312	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.688	0.312	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.688	0.312	0.000
T36 Poisoning by systemic antibiotics	0.688	0.312	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.688	0.312	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.686	0.314	0.000
R62 Lack of expected normal physiological development	0.686	0.314	0.000
R64 Cachexia	0.686	0.314	0.000
R58 Haemorrhage, not elsewhere classified	0.686	0.314	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.686	0.314	0.000
A49 Bacterial infection of unspecified site	0.686	0.314	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.685	0.315	0.000
M33 Dermatopolymyositis	0.685	0.315	0.000
M32 Systemic lupus erythematosus	0.685	0.315	0.000
M30 Polyarteritis nodosa and related conditions	0.685	0.315	0.000
E85 Amyloidosis	0.684	0.316	0.000
E84 Cystic fibrosis	0.684	0.316	0.000
E79 Disorders of purine and pyrimidine metabolism	0.684	0.316	0.000
E77 Disorders of glycoprotein metabolism	0.684	0.316	0.000
E76 Disorders of glycosaminoglycan metabolism	0.684	0.316	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.684	0.316	0.000
E74 Other disorders of carbohydrate metabolism	0.684	0.316	0.000
E73 Lactose intolerance	0.684	0.316	0.000
E72 Other disorders of amino-acid metabolism	0.684	0.316	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.684	0.316	0.000
E70 Disorders of aromatic amino-acid metabolism	0.684	0.316	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.684	0.316	0.000
X60-X84 Intentional self-harm	0.684	0.316	0.000
I51.6 Cardiovascular disease, unspecified	0.684	0.316	0.000
I51.5 Myocardial degeneration	0.684	0.316	0.000
I51.4 Myocarditis, unspecified	0.684	0.316	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.684	0.316	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.684	0.316	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.684	0.316	0.000
I51.0 Cardiac septal defect, acquired	0.684	0.316	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.682	0.318	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.682	0.318	0.000
R16.1 Splenomegaly, not elsewhere classified	0.682	0.318	0.000
W00-W19 Falls	0.681	0.318	0.000
S69 Other and unspecified injuries of wrist and hand	0.681	0.319	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.681	0.319	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.680	0.319	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.679	0.321	0.000
S61 Open wound of wrist and hand	0.679	0.321	0.000
I67 Other cerebrovascular diseases	0.678	0.322	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.676	0.324	0.000
T82.1 Mechanical complication of cardiac electronic device	0.676	0.324	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.675	0.325	0.000
B99-B99 Other infectious diseases	0.675	0.325	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.675	0.325	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.675	0.325	0.000
B65-B83 Helminthiases	0.675	0.325	0.000
B50-B64 Protozoal diseases	0.675	0.325	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.675	0.325	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.675	0.325	0.000
A80-A89 Viral infections of the central nervous system	0.675	0.325	0.000
A75-A79 Rickettsioses	0.675	0.325	0.000
A70-A74 Other diseases caused by chlamydiae	0.675	0.325	0.000
A65-A69 Other spirochaetal diseases	0.675	0.325	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.675	0.325	0.000
A20-A28 Certain zoonotic bacterial diseases	0.675	0.325	0.000
A15-A19 Tuberculosis	0.675	0.325	0.000
J20-J22 Other acute lower respiratory infections	0.674	0.326	0.000
B15-B19 Viral hepatitis	0.673	0.327	0.000
Z93.5 Cystostomy status	0.672	0.328	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.672	0.328	0.000
S42 Fracture of shoulder and upper arm	0.671	0.329	0.000
N18.0 End-stage renal disease	0.671	0.329	0.000
T40.4 Other synthetic narcotics	0.671	0.329	0.000
I49.9 Cardiac arrhythmia, unspecified	0.671	0.329	0.000
T40.2 Other opioids	0.670	0.330	0.000
I72.4 Aneurysm of artery of lower extremity	0.670	0.330	0.000
Chapter VII Diseases of the eye and adnexa	0.670	0.330	0.000
Z97 Presence of other devices	0.669	0.330	0.000
E00-E07 Disorders of thyroid gland	0.667	0.331	0.002
X40-X49 Accidental poisoning by and exposure to noxious substances	0.669	0.331	0.000
E89.2 Postprocedural hypoparathyroidism	0.668	0.331	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.668	0.332	0.000
E87.5 Hyperkalaemia	0.667	0.333	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.667	0.333	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.667	0.333	0.000
I31 Other diseases of pericardium	0.666	0.334	0.000
Z76 Persons encountering health services in other circumstances	0.665	0.335	0.000
M65-M68 Disorders of synovium and tendon	0.665	0.335	0.000
F30-F39 Mood [affective] disorders	0.663	0.337	0.000
Z87 Personal history of other diseases and conditions	0.663	0.337	0.000
R52.2 Other chronic pain	0.663	0.337	0.000
Z04.8 Examination and observation for other specified reasons	0.662	0.338	0.000
S65 Injury of blood vessels at wrist and hand level	0.662	0.338	0.000
S60 Superficial injury of wrist and hand	0.662	0.338	0.000
I21.9 Acute myocardial infarction, unspecified	0.661	0.339	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.661	0.339	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.660	0.340	0.000
I74.8 Embolism and thrombosis of other arteries	0.660	0.340	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.660	0.340	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.660	0.340	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.660	0.340	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.660	0.340	0.000
R06.7 Sneezing	0.660	0.340	0.000
R06.6 Hiccough	0.660	0.340	0.000
R06.3 Periodic breathing	0.660	0.340	0.000
R06.1 Stridor	0.660	0.340	0.000
Z04.3 Examination and observation following other accident	0.660	0.340	0.000
I44.7 Left bundle-branch block, unspecified	0.659	0.341	0.000
I46.0 Cardiac arrest with successful resuscitation	0.659	0.341	0.000
A41 Other septicaemia	0.659	0.341	0.000
E83.5 Disorders of calcium metabolism	0.659	0.341	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.659	0.341	0.000
Z95.3 Presence of xenogenic heart valve	0.657	0.342	0.000
M47.89 Other spondylosis (Site unspecified)	0.657	0.343	0.000
Z91.5 Personal history of self-harm	0.656	0.344	0.000
R06.8 Other and unspecified abnormalities of breathing	0.656	0.344	0.000
W25 Contact with sharp glass	0.655	0.345	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.655	0.345	0.000
Z80 Family history of malignant neoplasm	0.655	0.345	0.000
B25-B34 Other viral diseases	0.654	0.345	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.654	0.346	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.654	0.346	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.654	0.346	0.000
S68 Traumatic amputation of wrist and hand	0.654	0.346	0.000
M40-M43 Deforming dorsopathies	0.654	0.346	0.000
R59.9 Enlarged lymph nodes, unspecified	0.652	0.348	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.651	0.349	0.000
R49 Voice disturbances	0.650	0.350	0.000
F99-F99 Unspecified mental disorder	0.650	0.350	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.650	0.350	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.649	0.351	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.649	0.351	0.000
Z57.2 Occupational exposure to dust	0.647	0.353	0.000
E10-E14 Diabetes mellitus	0.646	0.354	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.646	0.354	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.646	0.354	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.646	0.354	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.646	0.354	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.646	0.354	0.000
I88 Nonspecific lymphadenitis	0.646	0.354	0.000
I81 Portal vein thrombosis	0.646	0.354	0.000
I99 Other and unspecified disorders of circulatory system	0.645	0.355	0.000
I45.5 Other specified heart block	0.644	0.356	0.000
V10-V19 Pedal cyclist injured in transport accident	0.643	0.357	0.000
R34 Anuria and oliguria	0.643	0.357	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.643	0.357	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.642	0.358	0.000
L50-L54 Urticaria and erythema	0.642	0.358	0.000
M24 Other specific joint derangements	0.641	0.359	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.641	0.359	0.000
W29 Contact with other powered hand tools and household machinery	0.641	0.359	0.000
I12 Hypertensive renal disease	0.641	0.359	0.000
Z73 Problems related to life-management difficulty	0.641	0.359	0.000
T66-T78 Other and unspecified effects of external causes	0.641	0.359	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.640	0.360	0.000
M47.82 Other spondylosis (Cervical region)	0.640	0.360	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.639	0.361	0.000
S82 Fracture of lower leg, including ankle	0.639	0.361	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.639	0.361	0.000
M31.6 Other giant cell arteritis	0.638	0.362	0.000
R80 Isolated proteinuria	0.637	0.363	0.000
I37.1 Pulmonary valve insufficiency	0.637	0.363	0.000
R09.0 Asphyxia	0.635	0.364	0.000
I49.8 Other specified cardiac arrhythmias	0.635	0.365	0.000
R01 Cardiac murmurs and other cardiac sounds	0.634	0.366	0.000
R47.8 Other and unspecified speech disturbances	0.634	0.366	0.000
T43.9 Psychotropic drug, unspecified	0.634	0.366	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.634	0.366	0.000
T43.6 Psychostimulants with abuse potential	0.634	0.366	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.634	0.366	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.634	0.366	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.634	0.366	0.000
Y35-Y36 Legal intervention and operations of war	0.634	0.366	0.000
Y10-Y34 Event of undetermined intent	0.634	0.366	0.000
X85-X99 Assault	0.634	0.366	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.634	0.366	0.000
X50-X57 Overexertion, travel and privation	0.634	0.366	0.000
X30-X39 Exposure to forces of nature	0.634	0.366	0.000
X20-X29 Contact with venomous animals and plants	0.634	0.366	0.000
X10-X19 Contact with heat and hot substances	0.634	0.366	0.000
X00-X09 Exposure to smoke, fire and flames	0.634	0.366	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.634	0.366	0.000
W75-W84 Other accidental threats to breathing	0.634	0.366	0.000
W65-W74 Accidental drowning and submersion	0.634	0.366	0.000
W50-W64 Exposure to animate mechanical forces	0.634	0.366	0.000
V98-V99 Other and unspecified transport accidents	0.634	0.366	0.000
V95-V97 Air and space transport accidents	0.634	0.366	0.000
V90-V94 Water transport accidents	0.634	0.366	0.000
V80-V89 Other land transport accidents	0.634	0.366	0.000
V70-V79 Bus occupant injured in transport accident	0.634	0.366	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.634	0.366	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations