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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117646115
log Bayes Factor = 8.28317
Chromosome 10   position 10,918,923  (GRCh37) Explore rs117646115 on Ensembl!
Variant rs117646115 is part of Cluster X0169

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
C79 Secondary malignant neoplasm of other sites
0.988 0.012 0.000
J90-J94 Other diseases of pleura
0.985 0.015 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.984 0.016 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.977 0.023 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.975 0.025 0.000
C77.9 Lymph node, unspecified
0.975 0.025 0.000
J95-J99 Other diseases of the respiratory system
0.971 0.029 0.000
C25 Malignant neoplasm of pancreas
0.964 0.036 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.962 0.038 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.958 0.042 0.000
H02 Other disorders of eyelid
0.957 0.043 0.000
L40-L45 Papulosquamous disorders
0.956 0.044 0.000
J90 Pleural effusion, not elsewhere classified
0.955 0.045 0.000
M05-M14 Inflammatory polyarthropathies
0.953 0.047 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.951 0.049 0.000
J98 Other respiratory disorders
0.947 0.053 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.946 0.054 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.943 0.057 0.000
C15 Malignant neoplasm of oesophagus
0.942 0.058 0.000
W00-W19 Falls
0.942 0.058 0.000
C43 Malignant melanoma of skin
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.938 0.062 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.937 0.063 0.000
Y95 Nosocomial condition
0.929 0.071 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.926 0.074 0.000
L40 Psoriasis
0.921 0.079 0.000
D00-D09 In situ neoplasms
0.917 0.083 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.917 0.083 0.000
M06 Other rheumatoid arthritis
0.912 0.088 0.000
C25.9 Pancreas, unspecified
0.909 0.091 0.000
J98.1 Pulmonary collapse
0.908 0.092 0.000
A30-A49 Other bacterial diseases
0.908 0.092 0.000
H55-H59 Other disorders of eye and adnexa
0.907 0.093 0.000
Chapter VIII Diseases of the ear and mastoid process
0.901 0.099 0.000
H02.0 Entropion and trichiasis of eyelid
0.897 0.103 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.895 0.105 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.892 0.108 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.892 0.108 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.891 0.109 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.891 0.109 0.000
H25-H28 Disorders of lens
0.887 0.113 0.000
H02.3 Blepharochalasis
0.886 0.114 0.000
H02.4 Ptosis of eyelid
0.886 0.114 0.000
S80-S89 Injuries to the knee and lower leg
0.886 0.114 0.000
L40.5 Arthropathic psoriasis
0.879 0.121 0.000
A41 Other septicaemia
0.875 0.125 0.000
C15.9 Oesophagus, unspecified
0.875 0.125 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.867 0.133 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.867 0.133 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.864 0.136 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.864 0.136 0.000
A41.9 Septicaemia, unspecified
0.862 0.138 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.861 0.139 0.000
C77.4 Inguinal and lower limb lymph nodes
0.856 0.144 0.000
L85 Other epidermal thickening
0.856 0.144 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.855 0.145 0.000
C16 Malignant neoplasm of stomach
0.854 0.146 0.000
T93 Sequelae of injuries of lower limb
0.849 0.151 0.000
H25 Senile cataract
0.848 0.152 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.847 0.153 0.000
H43-H45 Disorders of vitreous body and globe
0.847 0.153 0.000
J40-J47 Chronic lower respiratory diseases
0.845 0.155 0.000
L43 Lichen planus
0.845 0.155 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.844 0.155 0.000
J93 Pneumothorax
0.844 0.156 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.844 0.156 0.000
T79-T79 Certain early complications of trauma
0.841 0.159 0.000
J92 Pleural plaque
0.841 0.159 0.000
C77.8 Lymph nodes of multiple regions
0.839 0.161 0.000
M07 Psoriatic and enteropathic arthropathies
0.834 0.166 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.833 0.167 0.000
J47 Bronchiectasis
0.833 0.167 0.000
H90-H95 Other disorders of ear
0.831 0.169 0.000
T91 Sequelae of injuries of neck and trunk
0.831 0.169 0.000
C25.3 Pancreatic duct
0.828 0.172 0.000
H04 Disorders of lachrymal system
0.822 0.178 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.821 0.179 0.000
C43.5 Malignant melanoma of trunk
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.821 0.179 0.000
M06.9 Rheumatoid arthritis, unspecified
0.821 0.179 0.000
T66-T78 Other and unspecified effects of external causes
0.818 0.182 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.814 0.186 0.000
S00-S09 Injuries to the head
0.814 0.186 0.000
M05 Seropositive rheumatoid arthritis
0.811 0.189 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.810 0.189 0.000
M86-M90 Other osteopathies
0.810 0.189 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.804 0.196 0.000
V20-V29 Motorcycle rider injured in transport accident
0.804 0.196 0.000
H25.0 Senile incipient cataract
0.803 0.197 0.000
S20-S29 Injuries to the thorax
0.801 0.199 0.000
M11 Other crystal arthropathies
0.801 0.199 0.000
W15 Fall from cliff
0.798 0.202 0.000
V10-V19 Pedal cyclist injured in transport accident
0.797 0.203 0.000
S30.1 Contusion of abdominal wall
0.795 0.205 0.000
C15.4 Middle third of oesophagus
0.794 0.206 0.000
L50-L54 Urticaria and erythema
0.794 0.206 0.000
W19 Unspecified fall
0.792 0.208 0.000
H52 Disorders of refraction and accommodation
0.792 0.208 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.791 0.209 0.000
J98.9 Respiratory disorder, unspecified
0.791 0.209 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.791 0.209 0.000
M06.4 Inflammatory polyarthropathy
0.791 0.209 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.789 0.211 0.000
L85.8 Other specified epidermal thickening
0.785 0.215 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.785 0.215 0.000
X60-X84 Intentional self-harm
0.784 0.216 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.784 0.216 0.000
C79.2 Secondary malignant neoplasm of skin
0.784 0.216 0.000
Q80-Q89 Other congenital malformations
0.783 0.217 0.000
C21 Malignant neoplasm of anus and anal canal
0.782 0.218 0.000
C77.2 Intra-abdominal lymph nodes
0.782 0.218 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.774 0.226 0.000
Q00-Q07 Congenital malformations of the nervous system
0.773 0.227 0.000
L40.9 Psoriasis, unspecified
0.772 0.228 0.000
H21 Other disorders of iris and ciliary body
0.772 0.228 0.000
M20-M25 Other joint disorders
0.770 0.230 0.000
L85.9 Epidermal thickening, unspecified
0.770 0.230 0.000
C45 Mesothelioma
0.767 0.233 0.000
H44 Disorders of globe
0.766 0.234 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.765 0.235 0.000
L43.9 Lichen planus, unspecified
0.765 0.235 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.764 0.236 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.763 0.237 0.000
A49 Bacterial infection of unspecified site
0.763 0.237 0.000
T92 Sequelae of injuries of upper limb
0.762 0.238 0.000
H52.1 Myopia
0.762 0.238 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.760 0.240 0.000
S81 Open wound of lower leg
0.760 0.240 0.000
H55 Nystagmus and other irregular eye movements
0.760 0.240 0.000
W10 Fall on and from stairs and steps
0.759 0.241 0.000
C80 Malignant neoplasm without specification of site
0.758 0.242 0.000
D07.5 Prostate
0.757 0.243 0.000
J09-J18 Influenza and pneumonia
0.757 0.243 0.000
M60-M63 Disorders of muscles
0.756 0.244 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.756 0.244 0.000
H18 Other disorders of cornea
0.755 0.245 0.000
V40-V49 Car occupant injured in transport accident
0.754 0.246 0.000
L91 Hypertrophic disorders of skin
0.752 0.248 0.000
Y00-Y09 Assault
0.750 0.250 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.750 0.250 0.000
W08 Fall involving other furniture
0.749 0.251 0.000
M07.3 Other psoriatic arthropathies
0.749 0.251 0.000
H25.8 Other senile cataract
0.749 0.251 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.748 0.252 0.000
M80 Osteoporosis with pathological fracture
0.745 0.255 0.000
X50-X57 Overexertion, travel and privation
0.745 0.255 0.000
H92 Otalgia and effusion of ear
0.745 0.255 0.000
C32 Malignant neoplasm of larynx
0.743 0.257 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.741 0.258 0.000
D07.1 Vulva
0.741 0.259 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.740 0.260 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.739 0.261 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.738 0.262 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.738 0.262 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.737 0.263 0.000
J98.8 Other specified respiratory disorders
0.736 0.264 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.736 0.264 0.000
W19.9 Unspecified place
0.736 0.264 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.736 0.264 0.000
C25.0 Head of pancreas
0.735 0.265 0.000
A65-A69 Other spirochaetal diseases
0.734 0.266 0.000
W13 Fall from, out of or through building or structure
0.734 0.266 0.000
D46 Myelodysplastic syndromes
0.734 0.266 0.000
S10-S19 Injuries to the neck
0.733 0.267 0.000
C17 Malignant neoplasm of small intestine
0.733 0.267 0.000
L82 Seborrhoeic keratosis
0.733 0.267 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.732 0.267 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.732 0.267 0.000
T13 Other injuries of lower limb, level unspecified
0.732 0.268 0.000
H01 Other inflammation of eyelid
0.731 0.269 0.000
J98.6 Disorders of diaphragm
0.731 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.729 0.271 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.728 0.272 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.727 0.273 0.000
S37 Injury of urinary and pelvic organs
0.727 0.273 0.000
H60-H62 Diseases of external ear
0.726 0.274 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.725 0.275 0.000
J93.9 Pneumothorax, unspecified
0.725 0.275 0.000
A15-A19 Tuberculosis
0.724 0.276 0.000
C20 Malignant neoplasm of rectum
0.724 0.276 0.000
H02.2 Lagophthalmos
0.724 0.276 0.000
H04.1 Other disorders of lachrymal gland
0.723 0.277 0.000
S80 Superficial injury of lower leg
0.723 0.277 0.000
M91-M94 Chondropathies
0.723 0.277 0.000
H40-H42 Glaucoma
0.723 0.277 0.000
M65-M68 Disorders of synovium and tendon
0.719 0.281 0.000
Y85 Sequelae of transport accidents
0.718 0.282 0.000
M06.0 Seronegative rheumatoid arthritis
0.718 0.282 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
H10-H13 Disorders of conjunctiva
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
S05 Injury of eye and orbit
0.715 0.285 0.000
Q60-Q64 Congenital malformations of the urinary system
0.714 0.286 0.000
C23 Malignant neoplasm of gallbladder
0.714 0.286 0.000
H49 Paralytic strabismus
0.713 0.287 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.713 0.287 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.713 0.287 0.000
C16.9 Stomach, unspecified
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
L91.0 Keloid scar
0.710 0.290 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.291 0.000
S82 Fracture of lower leg, including ankle
0.709 0.291 0.000
M35 Other systemic involvement of connective tissue
0.709 0.291 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.708 0.291 0.000
D07.2 Vagina
0.709 0.291 0.000
H02.6 Xanthelasma of eyelid
0.708 0.292 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.708 0.292 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.707 0.293 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.294 0.000
J94 Other pleural conditions
0.704 0.296 0.000
M21 Other acquired deformities of limbs
0.704 0.296 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
S30.0 Contusion of lower back and pelvis
0.704 0.296 0.000
J92.0 Pleural plaque with presence of asbestos
0.704 0.296 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.704 0.296 0.000
B35-B49 Mycoses
0.703 0.297 0.000
T91.1 Sequelae of fracture of spine
0.702 0.298 0.000
D47.2 Monoclonal gammopathy
0.702 0.298 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
M85 Other disorders of bone density and structure
0.701 0.299 0.000
M84 Disorders of continuity of bone
0.701 0.299 0.000
W50-W64 Exposure to animate mechanical forces
0.701 0.299 0.000
L10-L14 Bullous disorders
0.700 0.300 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.699 0.301 0.000
C77.1 Intrathoracic lymph nodes
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.698 0.302 0.000
T93.2 Sequelae of other fractures of lower limb
0.698 0.302 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.698 0.302 0.000
H57 Other disorders of eye and adnexa
0.697 0.303 0.000
J96 Respiratory failure, not elsewhere classified
0.696 0.304 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.696 0.304 0.000
H02.5 Other disorders affecting eyelid function
0.695 0.305 0.000
W15.8 Other specified place
0.695 0.305 0.000
D47.4 Osteomyelofibrosis
0.694 0.306 0.000
J91 Pleural effusion in conditions classified elsewhere
0.693 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.693 0.307 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.692 0.308 0.000
M11.2 Other chondrocalcinosis
0.691 0.309 0.000
C25.8 Overlapping lesion of pancreas
0.691 0.309 0.000
C25.7 Other parts of pancreas
0.691 0.309 0.000
C25.4 Endocrine pancreas
0.691 0.309 0.000
C25.2 Tail of pancreas
0.691 0.309 0.000
C25.1 Body of pancreas
0.691 0.309 0.000
M24 Other specific joint derangements
0.690 0.310 0.000
J81 Pulmonary oedema
0.690 0.310 0.000
S36 Injury of intra-abdominal organs
0.689 0.311 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.688 0.312 0.000
M10 Gout
0.688 0.312 0.000
T78 Adverse effects, not elsewhere classified
0.688 0.312 0.000
H02.1 Ectropion of eyelid
0.687 0.313 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.687 0.313 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.686 0.313 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.686 0.313 0.000
Y98 Lifestyle-related condition
0.686 0.313 0.000
Y97 Environmental-pollution-related condition
0.686 0.313 0.000
Y96 Work-related condition
0.686 0.313 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.686 0.314 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.686 0.314 0.000
L44 Other papulosquamous disorders
0.686 0.314 0.000
L41 Parapsoriasis
0.686 0.314 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.686 0.314 0.000
L42 Pityriasis rosea
0.686 0.314 0.000
L52 Erythema nodosum
0.685 0.315 0.000
L80 Vitiligo
0.684 0.316 0.000
M12 Other specific arthropathies
0.683 0.316 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.683 0.316 0.000
M08 Juvenile arthritis
0.683 0.316 0.000
C16.0 Cardia
0.683 0.317 0.000
H44.2 Degenerative myopia
0.682 0.318 0.000
W07 Fall involving chair
0.682 0.318 0.000
B99-B99 Other infectious diseases
0.682 0.318 0.000
B65-B83 Helminthiases
0.681 0.319 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.681 0.319 0.000
A40 Streptococcal septicaemia
0.680 0.320 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.679 0.321 0.000
J98.3 Compensatory emphysema
0.679 0.321 0.000
J98.2 Interstitial emphysema
0.679 0.321 0.000
H65-H75 Diseases of middle ear and mastoid
0.679 0.321 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.678 0.322 0.000
Q35-Q37 Cleft lip and cleft palate
0.678 0.322 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.678 0.322 0.000
W18 Other fall on same level
0.677 0.323 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.677 0.323 0.000
L83 Acanthosis nigricans
0.676 0.324 0.000
S86 Injury of muscle and tendon at lower leg level
0.676 0.324 0.000
T95 Sequelae of burns, corrosions and frostbite
0.676 0.324 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.676 0.324 0.000
S06 Intracranial injury
0.676 0.324 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.676 0.324 0.000
Y88 Sequelae of surgical and medical care as external cause
0.676 0.324 0.000
T98 Sequelae of other and unspecified effects of external causes
0.675 0.324 0.000
C15.8 Overlapping lesion of oesophagus
0.675 0.324 0.000
C15.3 Upper third of oesophagus
0.675 0.324 0.000
C15.2 Abdominal part of oesophagus
0.675 0.324 0.000
C15.1 Thoracic part of oesophagus
0.675 0.324 0.000
C15.0 Cervical part of oesophagus
0.675 0.324 0.000
M35.0 Sicca syndrome [Sjogren]
0.676 0.324 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.675 0.324 0.000
H04.2 Epiphora
0.675 0.325 0.000
W17 Other fall from one level to another
0.675 0.325 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.675 0.325 0.000
W14 Fall from tree
0.675 0.325 0.000
W12 Fall on and from scaffolding
0.675 0.325 0.000
W11 Fall on and from ladder
0.675 0.325 0.000
W09 Fall involving playground equipment
0.675 0.325 0.000
W05 Fall involving wheelchair
0.675 0.325 0.000
W04 Fall while being carried or supported by other persons
0.675 0.325 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.675 0.325 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.675 0.325 0.000
W00 Fall on same level involving ice and snow
0.675 0.325 0.000
H92.1 Otorrhoea
0.675 0.325 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
J60-J70 Lung diseases due to external agents
0.674 0.326 0.000
C22.0 Liver cell carcinoma
0.673 0.327 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.673 0.327 0.000
C43.8 Overlapping malignant melanoma of skin
0.673 0.327 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.673 0.327 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.673 0.327 0.000
C43.0 Malignant melanoma of lip
0.673 0.327 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.673 0.327 0.000
B50-B64 Protozoal diseases
0.673 0.327 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.673 0.327 0.000
A75-A79 Rickettsioses
0.673 0.327 0.000
A70-A74 Other diseases caused by chlamydiae
0.673 0.327 0.000
A20-A28 Certain zoonotic bacterial diseases
0.673 0.327 0.000
M06.3 Rheumatoid nodule
0.673 0.327 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.672 0.328 0.000
H05 Disorders of orbit
0.672 0.328 0.000
S90-S99 Injuries to the ankle and foot
0.672 0.328 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.671 0.328 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.671 0.328 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.671 0.328 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.671 0.328 0.000
C15.5 Lower third of oesophagus
0.671 0.329 0.000
M90 Osteopathies in diseases classified elsewhere
0.670 0.330 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.669 0.331 0.000
S81.0 Open wound of knee
0.669 0.331 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.668 0.332 0.000
C34 Malignant neoplasm of bronchus and lung
0.667 0.333 0.000
B25-B34 Other viral diseases
0.667 0.333 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.665 0.334 0.000
M14 Arthropathies in other diseases classified elsewhere
0.665 0.334 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.664 0.336 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.664 0.336 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.664 0.336 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.664 0.336 0.000
S31 Open wound of abdomen, lower back and pelvis
0.664 0.336 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.664 0.336 0.000
C43.4 Malignant melanoma of scalp and neck
0.663 0.336 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.662 0.338 0.000
J92.9 Pleural plaque without asbestos
0.661 0.339 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.661 0.339 0.000
H16 Keratitis
0.661 0.339 0.000
L40.8 Other psoriasis
0.660 0.340 0.000
L40.4 Guttate psoriasis
0.660 0.340 0.000
L40.3 Pustulosis palmaris et plantaris
0.660 0.340 0.000
L40.2 Acrodermatitis continua
0.660 0.340 0.000
L40.1 Generalised pustular psoriasis
0.660 0.340 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.660 0.340 0.000
L93 Lupus erythematosus
0.659 0.341 0.000
C21.0 Anus, unspecified
0.658 0.342 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.658 0.342 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.657 0.342 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.656 0.344 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.656 0.344 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.654 0.346 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.654 0.346 0.000
M06.8 Other specified rheumatoid arthritis
0.654 0.346 0.000
M06.2 Rheumatoid bursitis
0.654 0.346 0.000
M06.1 Adult-onset Still's disease
0.654 0.346 0.000
H90 Conductive and sensorineural hearing loss
0.654 0.346 0.000
S20 Superficial injury of thorax
0.653 0.347 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.652 0.348 0.000
Q07 Other congenital malformations of nervous system
0.651 0.349 0.000
T13.0 Superficial injury of lower limb, level unspecified
0.651 0.349 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.651 0.349 0.000
A48 Other bacterial diseases, not elsewhere classified
0.651 0.349 0.000
A44 Bartonellosis
0.651 0.349 0.000
A43 Nocardiosis
0.651 0.349 0.000
A42 Actinomycosis
0.651 0.349 0.000
A39 Meningococcal infection
0.651 0.349 0.000
A37 Whooping cough
0.651 0.349 0.000
A36 Diphtheria
0.651 0.349 0.000
A32 Listeriosis
0.651 0.349 0.000
A31 Infection due to other mycobacteria
0.651 0.349 0.000
A30 Leprosy [Hansen's disease]
0.651 0.349 0.000
A38 Scarlet fever
0.651 0.349 0.000
A35 Other tetanus
0.651 0.349 0.000
A34 Obstetrical tetanus
0.651 0.349 0.000
A33 Tetanus neonatorum
0.651 0.349 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.650 0.350 0.000
Q23 Congenital malformations of aortic and mitral valves
0.649 0.351 0.000
M40-M43 Deforming dorsopathies
0.647 0.353 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.647 0.353 0.000
Q25 Congenital malformations of great arteries
0.646 0.354 0.000
M13 Other arthritis
0.646 0.354 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.645 0.355 0.000
C64-C68 Malignant neoplasms of urinary tract
0.645 0.355 0.000
D03 Melanoma in situ
0.645 0.355 0.000
M00-M03 Infectious arthropathies
0.645 0.355 0.000
D06 Carcinoma in situ of cervix uteri
0.644 0.356 0.000
J86 Pyothorax
0.643 0.356 0.000
L40.0 Psoriasis vulgaris
0.643 0.357 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.643 0.357 0.000
H27 Other disorders of lens
0.643 0.357 0.000
Y86 Sequelae of other accidents
0.643 0.357 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.643 0.357 0.000
S00 Superficial injury of head
0.642 0.358 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.642 0.358 0.000
C46 Kaposi's sarcoma
0.642 0.358 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.641 0.358 0.000
S40 Superficial injury of shoulder and upper arm
0.641 0.359 0.000
C01 Malignant neoplasm of base of tongue
0.641 0.359 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.640 0.360 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.640 0.360 0.000
H17 Corneal scars and opacities
0.640 0.360 0.000
H15 Disorders of sclera
0.640 0.360 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.639 0.360 0.000
S30.2 Contusion of external genital organs
0.639 0.360 0.000
S29 Other and unspecified injuries of thorax
0.639 0.361 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.638 0.361 0.000
L94 Other localised connective tissue disorders
0.638 0.361 0.000
L87 Transepidermal elimination disorders
0.638 0.361 0.000
L88 Pyoderma gangrenosum
0.638 0.361 0.000
L86 Keratoderma in diseases classified elsewhere
0.638 0.361 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.638 0.362 0.000
S05.1 Contusion of eyeball and orbital tissues
0.637 0.363 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.636 0.364 0.000
S88 Traumatic amputation of lower leg
0.635 0.365 0.000
S87 Crushing injury of lower leg
0.635 0.365 0.000
S85 Injury of blood vessels at lower leg level
0.635 0.365 0.000
S84 Injury of nerves at lower leg level
0.635 0.365 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.634 0.365 0.000
M88 Paget's disease of bone [osteitis deformans]
0.634 0.366 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.634 0.366 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.633 0.367 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.633 0.367 0.000
Q82 Other congenital malformations of skin
0.632 0.368 0.000
A80-A89 Viral infections of the central nervous system
0.632 0.368 0.000
D37.7 Other digestive organs
0.632 0.368 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.632 0.368 0.000
C32.9 Larynx, unspecified
0.631 0.368 0.000
J93.1 Other spontaneous pneumothorax
0.631 0.369 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.630 0.369 0.000
Q21 Congenital malformations of cardiac septa
0.630 0.370 0.000
C09 Malignant neoplasm of tonsil
0.629 0.370 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.628 0.372 0.000
A41.4 Septicaemia due to anaerobes
0.627 0.372 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.627 0.372 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.627 0.372 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.627 0.373 0.000
H51 Other disorders of binocular movement
0.625 0.375 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.625 0.375 0.000
W10.8 Other specified place
0.624 0.376 0.000
C43.9 Malignant melanoma of skin, unspecified
0.623 0.377 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.623 0.377 0.000
A49.9 Bacterial infection, unspecified
0.623 0.377 0.000
D09 Carcinoma in situ of other and unspecified sites
0.622 0.378 0.000
M83 Adult osteomalacia
0.622 0.378 0.000
M82 Osteoporosis in diseases classified elsewhere
0.622 0.378 0.000
D07.6 Other and unspecified male genital organs
0.621 0.379 0.000
D07.4 Penis
0.621 0.379 0.000
D07.3 Other and unspecified female genital organs
0.621 0.379 0.000
D07.0 Endometrium
0.621 0.379 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.621 0.379 0.000
B15-B19 Viral hepatitis
0.620 0.379 0.000
T14 Injury of unspecified body region
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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