TreeWAS – Variant ID: rs117677736

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
M15-M19 Arthrosis	0.998	0.002	0.000
Chapter XX External causes of morbidity and mortality	0.997	0.003	0.000
Chapter VI Diseases of the nervous system	0.997	0.003	0.000
M20-M25 Other joint disorders	0.996	0.004	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.994	0.006	0.000
M19 Other arthrosis	0.983	0.017	0.000
M70-M79 Other soft tissue disorders	0.981	0.019	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.981	0.019	0.000
M79.6 Pain in limb	0.978	0.022	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.978	0.022	0.000
M19.9 Arthrosis, unspecified	0.976	0.024	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.972	0.028	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.970	0.030	0.000
G30-G32 Other degenerative diseases of the nervous system	0.968	0.032	0.000
M24 Other specific joint derangements	0.968	0.032	0.000
S70-S79 Injuries to the hip and thigh	0.967	0.033	0.000
S40-S49 Injuries to the shoulder and upper arm	0.965	0.035	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.963	0.037	0.000
M79.66 Pain in limb (Lower leg)	0.962	0.038	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.958	0.042	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.949	0.051	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.947	0.053	0.000
S72 Fracture of femur	0.945	0.055	0.000
M25 Other joint disorders, not elsewhere classified	0.944	0.056	0.000
M16 Coxarthrosis [arthrosis of hip]	0.944	0.056	0.000
S42 Fracture of shoulder and upper arm	0.938	0.062	0.000
Chapter I Certain infectious and parasitic diseases	0.938	0.062	0.000
S20-S29 Injuries to the thorax	0.936	0.064	0.000
M65-M68 Disorders of synovium and tendon	0.933	0.067	0.000
Chapter VIII Diseases of the ear and mastoid process	0.932	0.068	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.931	0.069	0.000
Y95 Nosocomial condition	0.927	0.073	0.000
G20-G26 Extrapyramidal and movement disorders	0.921	0.079	0.000
M16.0 Primary coxarthrosis, bilateral	0.921	0.079	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.918	0.082	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.913	0.087	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.913	0.087	0.000
S72.0 Fracture of neck of femur	0.908	0.092	0.000
M17 Gonarthrosis [arthrosis of knee]	0.907	0.093	0.000
G90-G99 Other disorders of the nervous system	0.904	0.096	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.902	0.098	0.000
B35-B49 Mycoses	0.899	0.101	0.000
M17.1 Other primary gonarthrosis	0.897	0.103	0.000
Chapter X Diseases of the respiratory system	0.896	0.104	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.894	0.106	0.000
M24.1 Other articular cartilage disorders	0.893	0.107	0.000
H90-H95 Other disorders of ear	0.892	0.108	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.887	0.113	0.000
S72.00 Fracture of neck of femur (closed)	0.881	0.119	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.878	0.122	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.871	0.129	0.000
M19.94 Arthrosis, unspecified (Hand)	0.868	0.132	0.000
S42.0 Fracture of clavicle	0.867	0.133	0.000
M79.62 Pain in limb (Upper arm)	0.865	0.135	0.000
W20-W49 Exposure to inanimate mechanical forces	0.864	0.136	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.864	0.136	0.000
M34 Systemic sclerosis	0.863	0.137	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.861	0.139	0.000
M21 Other acquired deformities of limbs	0.860	0.140	0.000
M91-M94 Chondropathies	0.858	0.142	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.855	0.145	0.000
S60-S69 Injuries to the wrist and hand	0.852	0.148	0.000
B37 Candidiasis	0.848	0.152	0.000
W00-W19 Falls	0.845	0.155	0.000
M79.67 Pain in limb (Ankle and foot)	0.845	0.155	0.000
M65 Synovitis and tenosynovitis	0.844	0.156	0.000
J20-J22 Other acute lower respiratory infections	0.842	0.158	0.000
G20 Parkinson's disease	0.839	0.161	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.835	0.165	0.000
Y57 Other and unspecified drugs and medicaments	0.834	0.166	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.832	0.168	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.831	0.169	0.000
H93 Other disorders of ear, not elsewhere classified	0.829	0.171	0.000
G63.2 Diabetic polyneuropathy	0.828	0.172	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.828	0.172	0.000
B37.8 Candidiasis of other sites	0.827	0.173	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.826	0.174	0.000
M79.69 Pain in limb (Site unspecified)	0.826	0.174	0.000
M79.64 Pain in limb (Hand)	0.826	0.174	0.000
M23 Internal derangement of knee	0.825	0.175	0.000
Y52 Agents primarily affecting the cardiovascular system	0.824	0.176	0.000
G62 Other polyneuropathies	0.820	0.180	0.000
M79.63 Pain in limb (Forearm)	0.819	0.181	0.000
G30 Alzheimer's disease	0.819	0.181	0.000
W44 Foreign body entering into or through eye or natural orifice	0.816	0.184	0.000
M24.2 Disorder of ligament	0.815	0.185	0.000
S42.00 Fracture of clavicle (closed)	0.815	0.185	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.815	0.185	0.000
S72.3 Fracture of shaft of femur	0.814	0.186	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.813	0.187	0.000
G70-G73 Diseases of myoneural junction and muscle	0.809	0.190	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.809	0.191	0.000
D50-D53 Nutritional anaemias	0.809	0.191	0.000
M16.9 Coxarthrosis, unspecified	0.808	0.192	0.000
D55-D59 Haemolytic anaemias	0.807	0.193	0.000
S42.1 Fracture of scapula	0.805	0.194	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.805	0.195	0.000
S90-S99 Injuries to the ankle and foot	0.805	0.195	0.000
G90 Disorders of autonomic nervous system	0.805	0.195	0.000
B95-B98 Bacterial, viral and other infectious agents	0.803	0.197	0.000
M86-M90 Other osteopathies	0.802	0.198	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.800	0.200	0.000
G40-G47 Episodic and paroxysmal disorders	0.799	0.201	0.000
V40-V49 Car occupant injured in transport accident	0.793	0.207	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.793	0.207	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.791	0.208	0.000
T85.2 Mechanical complication of intraocular lens	0.788	0.212	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.787	0.213	0.000
M25.9 Joint disorder, unspecified	0.785	0.215	0.000
H93.1 Tinnitus	0.785	0.215	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.784	0.216	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.783	0.217	0.000
D68 Other coagulation defects	0.783	0.217	0.000
W44.0 Home	0.782	0.218	0.000
J22 Unspecified acute lower respiratory infection	0.781	0.219	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.778	0.222	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.777	0.223	0.000
M79.0 Rheumatism, unspecified	0.776	0.224	0.000
M40-M43 Deforming dorsopathies	0.775	0.225	0.000
S40 Superficial injury of shoulder and upper arm	0.775	0.225	0.000
M15 Polyarthrosis	0.771	0.229	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.770	0.230	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.769	0.231	0.000
M33 Dermatopolymyositis	0.768	0.232	0.000
M31 Other necrotising vasculopathies	0.767	0.233	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.766	0.233	0.001
S27 Injury of other and unspecified intrathoracic organs	0.765	0.235	0.000
Y00-Y09 Assault	0.765	0.235	0.000
W50-W64 Exposure to animate mechanical forces	0.764	0.236	0.000
J09-J18 Influenza and pneumonia	0.763	0.237	0.000
T82.3 Mechanical complication of other vascular grafts	0.761	0.239	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.757	0.243	0.000
T87 Complications peculiar to reattachment and amputation	0.754	0.246	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.752	0.248	0.000
W06 Fall involving bed	0.751	0.249	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.750	0.250	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.750	0.250	0.000
M66 Spontaneous rupture of synovium and tendon	0.750	0.250	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.749	0.251	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.749	0.251	0.000
M25.0 Haemarthrosis	0.747	0.253	0.000
H90 Conductive and sensorineural hearing loss	0.747	0.253	0.000
J40-J47 Chronic lower respiratory diseases	0.747	0.253	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.745	0.255	0.000
M25.3 Other instability of joint	0.744	0.256	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.744	0.256	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.744	0.256	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.743	0.257	0.000
S22.4 Multiple fractures of ribs	0.743	0.257	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.743	0.257	0.000
M00-M03 Infectious arthropathies	0.742	0.257	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.741	0.259	0.000
G31.8 Other specified degenerative diseases of nervous system	0.741	0.259	0.000
D69 Purpura and other haemorrhagic conditions	0.739	0.261	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.739	0.261	0.000
J90-J94 Other diseases of pleura	0.739	0.261	0.000
M21.3 Wrist or foot drop (acquired)	0.738	0.262	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.737	0.263	0.000
T82.1 Mechanical complication of cardiac electronic device	0.736	0.264	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.733	0.267	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.733	0.267	0.000
S64 Injury of nerves at wrist and hand level	0.733	0.267	0.000
M67 Other disorders of synovium and tendon	0.731	0.269	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.731	0.269	0.000
X50-X57 Overexertion, travel and privation	0.730	0.270	0.000
B44 Aspergillosis	0.729	0.271	0.000
M30 Polyarteritis nodosa and related conditions	0.729	0.271	0.000
M60-M63 Disorders of muscles	0.728	0.272	0.000
M71 Other bursopathies	0.728	0.272	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.727	0.273	0.000
H80-H83 Diseases of inner ear	0.726	0.274	0.000
M25.7 Osteophyte	0.726	0.274	0.000
Y45.1 Salicylates	0.725	0.275	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.725	0.275	0.000
T51 Toxic effect of alcohol	0.725	0.275	0.000
T18 Foreign body in alimentary tract	0.723	0.277	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.723	0.277	0.000
M79.2 Neuralgia and neuritis, unspecified	0.722	0.278	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.721	0.279	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.720	0.279	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.720	0.280	0.000
S72.30 Fracture of shaft of femur (closed)	0.720	0.280	0.000
M24.0 Loose body in joint	0.719	0.281	0.000
Chapter XXII Codes for special purposes	0.719	0.281	0.000
A65-A69 Other spirochaetal diseases	0.718	0.282	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.718	0.282	0.000
J60-J70 Lung diseases due to external agents	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
M94 Other disorders of cartilage	0.717	0.283	0.000
D50 Iron deficiency anaemia	0.716	0.284	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.716	0.284	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.715	0.285	0.000
Y35-Y36 Legal intervention and operations of war	0.715	0.285	0.000
Y10-Y34 Event of undetermined intent	0.715	0.285	0.000
X85-X99 Assault	0.715	0.285	0.000
X30-X39 Exposure to forces of nature	0.715	0.285	0.000
X20-X29 Contact with venomous animals and plants	0.715	0.285	0.000
X10-X19 Contact with heat and hot substances	0.715	0.285	0.000
X00-X09 Exposure to smoke, fire and flames	0.715	0.285	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285	0.000
W75-W84 Other accidental threats to breathing	0.715	0.285	0.000
W65-W74 Accidental drowning and submersion	0.715	0.285	0.000
V98-V99 Other and unspecified transport accidents	0.715	0.285	0.000
V95-V97 Air and space transport accidents	0.715	0.285	0.000
V90-V94 Water transport accidents	0.715	0.285	0.000
V70-V79 Bus occupant injured in transport accident	0.715	0.285	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285	0.000
V01-V09 Pedestrian injured in transport accident	0.715	0.285	0.000
S72.1 Pertrochanteric fracture	0.714	0.285	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.714	0.286	0.000
M32 Systemic lupus erythematosus	0.714	0.286	0.000
G60 Hereditary and idiopathic neuropathy	0.714	0.286	0.000
M76 Enthesopathies of lower limb, excluding foot	0.714	0.286	0.000
G24 Dystonia	0.713	0.286	0.000
G30.9 Alzheimer's disease, unspecified	0.712	0.288	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.711	0.289	0.000
S42.10 Fracture of scapula (closed)	0.710	0.289	0.000
M23.0 Cystic meniscus	0.706	0.294	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.706	0.294	0.000
S72.2 Subtrochanteric fracture	0.705	0.294	0.000
M19.8 Other specified arthrosis	0.705	0.295	0.000
M19.2 Other secondary arthrosis	0.705	0.295	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.704	0.296	0.000
M34.9 Systemic sclerosis, unspecified	0.704	0.296	0.000
G25 Other extrapyramidal and movement disorders	0.704	0.296	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.703	0.297	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.703	0.297	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.703	0.297	0.000
S10-S19 Injuries to the neck	0.703	0.297	0.000
B37.3 Candidiasis of vulva and vagina	0.703	0.297	0.000
S42.3 Fracture of shaft of humerus	0.702	0.298	0.000
M79.68 Pain in limb (Other)	0.701	0.298	0.000
M79.61 Pain in limb (Shoulder region)	0.701	0.298	0.000
B99-B99 Other infectious diseases	0.701	0.298	0.000
M79.9 Soft tissue disorder, unspecified	0.701	0.299	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.701	0.299	0.000
M79.3 Panniculitis, unspecified	0.701	0.299	0.000
S42.2 Fracture of upper end of humerus	0.701	0.299	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.701	0.299	0.000
J47 Bronchiectasis	0.701	0.299	0.000
D75 Other diseases of blood and blood-forming organs	0.700	0.300	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.700	0.300	0.000
V20-V29 Motorcycle rider injured in transport accident	0.699	0.301	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.699	0.301	0.000
M17.3 Other posttraumatic gonarthrosis	0.698	0.302	0.000
M65.8 Other synovitis and tenosynovitis	0.698	0.302	0.000
M50-M54 Other dorsopathies	0.698	0.302	0.000
G62.9 Polyneuropathy, unspecified	0.697	0.303	0.000
T66-T78 Other and unspecified effects of external causes	0.697	0.303	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.697	0.303	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.697	0.303	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.696	0.304	0.000
S22.0 Fracture of thoracic vertebra	0.696	0.304	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.696	0.304	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.696	0.304	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.696	0.304	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.695	0.305	0.000
M79.7 Fibromyalgia	0.695	0.305	0.000
J18 Pneumonia, organism unspecified	0.694	0.306	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.694	0.306	0.000
M24.9 Joint derangement, unspecified	0.694	0.306	0.000
M24.7 Protrusio acetabuli	0.694	0.306	0.000
M24.6 Ankylosis of joint	0.694	0.306	0.000
M24.5 Contracture of joint	0.694	0.306	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.694	0.306	0.000
G96 Other disorders of central nervous system	0.694	0.306	0.000
S42.4 Fracture of lower end of humerus	0.694	0.306	0.000
S78 Traumatic amputation of hip and thigh	0.693	0.307	0.000
S77 Crushing injury of hip and thigh	0.693	0.307	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.693	0.307	0.000
S75 Injury of blood vessels at hip and thigh level	0.693	0.307	0.000
S74 Injury of nerves at hip and thigh level	0.693	0.307	0.000
T79-T79 Certain early complications of trauma	0.693	0.307	0.000
S79 Other and unspecified injuries of hip and thigh	0.693	0.307	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.693	0.307	0.000
M23.4 Loose body in knee	0.693	0.307	0.000
Y57.6 Other diagnostic agents	0.692	0.308	0.000
S48 Traumatic amputation of shoulder and upper arm	0.692	0.308	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.692	0.308	0.000
S44 Injury of nerves at shoulder and upper arm level	0.692	0.308	0.000
S41 Open wound of shoulder and upper arm	0.692	0.308	0.000
S47 Crushing injury of shoulder and upper arm	0.692	0.308	0.000
G93 Other disorders of brain	0.692	0.308	0.000
B49 Unspecified mycosis	0.692	0.308	0.000
H60-H62 Diseases of external ear	0.691	0.309	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.691	0.309	0.000
Y98 Lifestyle-related condition	0.691	0.309	0.000
Y97 Environmental-pollution-related condition	0.691	0.309	0.000
Y96 Work-related condition	0.691	0.309	0.000
J21 Acute bronchiolitis	0.691	0.309	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.690	0.310	0.000
S71 Open wound of hip and thigh	0.689	0.311	0.000
S20 Superficial injury of thorax	0.689	0.311	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.689	0.311	0.000
D60-D64 Aplastic and other anaemias	0.689	0.311	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.689	0.311	0.000
M34.8 Other forms of systemic sclerosis	0.688	0.312	0.000
W08 Fall involving other furniture	0.687	0.313	0.000
M21.4 Flat foot [pes planus] (acquired)	0.685	0.315	0.000
S29 Other and unspecified injuries of thorax	0.685	0.315	0.000
Y45.2 Propionic acid derivatives	0.685	0.315	0.000
W06.0 Home	0.683	0.317	0.000
Y45.8 Other analgesics and antipyretics	0.683	0.317	0.000
Y59 Other and unspecified vaccines and biological substances	0.680	0.320	0.000
Y58 Bacterial vaccines	0.680	0.320	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.680	0.320	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.680	0.320	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.680	0.320	0.000
Y48 Anaesthetics and therapeutic gases	0.680	0.320	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.680	0.320	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.680	0.320	0.000
G90.3 Multisystem degeneration	0.680	0.320	0.000
S22.5 Flail chest	0.680	0.320	0.000
G64 Other disorders of peripheral nervous system	0.679	0.321	0.000
M65.1 Other infective (teno)synovitis	0.678	0.322	0.000
S72.9 Fracture of femur, part unspecified	0.678	0.322	0.000
S72.8 Fractures of other parts of femur	0.678	0.322	0.000
S72.7 Multiple fractures of femur	0.678	0.322	0.000
M25.2 Flail joint	0.677	0.323	0.000
M25.1 Fistula of joint	0.677	0.323	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.677	0.323	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.677	0.323	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.677	0.323	0.000
B00 Herpesviral [herpes simplex] infections	0.676	0.323	0.000
M16.5 Other posttraumatic coxarthrosis	0.676	0.324	0.000
V80-V89 Other land transport accidents	0.675	0.325	0.000
S67 Crushing injury of wrist and hand	0.674	0.326	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.674	0.326	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.673	0.327	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.673	0.327	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.672	0.327	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.672	0.327	0.000
B50-B64 Protozoal diseases	0.672	0.327	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.672	0.327	0.000
A75-A79 Rickettsioses	0.672	0.327	0.000
A70-A74 Other diseases caused by chlamydiae	0.672	0.327	0.000
A20-A28 Certain zoonotic bacterial diseases	0.672	0.327	0.000
A15-A19 Tuberculosis	0.672	0.327	0.000
M22 Disorders of patella	0.672	0.328	0.000
S70 Superficial injury of hip and thigh	0.672	0.328	0.000
S22.1 Multiple fractures of thoracic spine	0.671	0.329	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.671	0.329	0.000
S26 Injury of heart	0.671	0.329	0.000
S25 Injury of blood vessels of thorax	0.671	0.329	0.000
S24 Injury of nerves and spinal cord at thorax level	0.671	0.329	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.671	0.329	0.000
S21 Open wound of thorax	0.671	0.329	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.669	0.331	0.000
A80-A89 Viral infections of the central nervous system	0.669	0.331	0.000
D80-D89 Certain disorders involving the immune mechanism	0.669	0.331	0.000
V10-V19 Pedal cyclist injured in transport accident	0.669	0.331	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.669	0.331	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.669	0.331	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.668	0.332	0.000
G31.2 Degeneration of nervous system due to alcohol	0.667	0.332	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.667	0.332	0.000
G31.0 Circumscribed brain atrophy	0.667	0.332	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.667	0.333	0.000
H81 Disorders of vestibular function	0.666	0.334	0.000
H91 Other hearing loss	0.666	0.334	0.000
D58 Other hereditary haemolytic anaemias	0.666	0.334	0.000
D66 Hereditary factor VIII deficiency	0.665	0.335	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.665	0.335	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.665	0.335	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.664	0.336	0.000
J40 Bronchitis, not specified as acute or chronic	0.663	0.337	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.662	0.337	0.000
M19.1 Posttraumatic arthrosis of other joints	0.662	0.338	0.000
S22.40 Multiple fractures of ribs (closed)	0.662	0.338	0.000
M89 Other disorders of bone	0.662	0.338	0.000
D53 Other nutritional anaemias	0.662	0.338	0.000
G23 Other degenerative diseases of basal ganglia	0.660	0.339	0.000
G21 Secondary Parkinsonism	0.660	0.339	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.660	0.339	0.000
G22 Parkinsonism in diseases classified elsewhere	0.660	0.339	0.000
B65-B83 Helminthiases	0.660	0.339	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.660	0.340	0.000
M21.2 Flexion deformity	0.660	0.340	0.000
M34.1 CR(E)ST syndrome	0.660	0.340	0.000
M93 Other osteochondropathies	0.659	0.340	0.000
G95 Other diseases of spinal cord	0.659	0.341	0.000
M72 Fibroblastic disorders	0.659	0.341	0.000
Y57.5 X-ray contrast media	0.659	0.341	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.659	0.341	0.000
B15-B19 Viral hepatitis	0.659	0.341	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.658	0.342	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.656	0.344	0.000
G72 Other myopathies	0.655	0.345	0.000
V48 Car occupant injured in noncollision transport accident	0.654	0.345	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.654	0.346	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.654	0.346	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.654	0.346	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.654	0.346	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.654	0.346	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.654	0.346	0.000
D68.5 Primary Thrombophilia	0.653	0.347	0.000
M25.4 Effusion of joint	0.653	0.347	0.000
S90 Superficial injury of ankle and foot	0.653	0.347	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.651	0.349	0.000
S72.01 Fracture of neck of femur (open)	0.651	0.349	0.000
G44 Other headache syndromes	0.651	0.349	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.651	0.349	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.651	0.349	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.651	0.349	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.651	0.349	0.000
G62.8 Other specified polyneuropathies	0.650	0.350	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.648	0.352	0.000
G92 Toxic encephalopathy	0.648	0.352	0.000
S72.4 Fracture of lower end of femur	0.647	0.353	0.000
G90.2 Horner's syndrome	0.647	0.353	0.000
D67 Hereditary factor IX deficiency	0.646	0.354	0.000
B37.4 Candidiasis of other urogenital sites	0.646	0.354	0.000
M92 Other juvenile osteochondrosis	0.645	0.354	0.000
W10 Fall on and from stairs and steps	0.645	0.355	0.000
B48 Other mycoses, not elsewhere classified	0.644	0.356	0.000
B47 Mycetoma	0.644	0.356	0.000
B46 Zygomycosis	0.644	0.356	0.000
B45 Cryptococcosis	0.644	0.356	0.000
B43 Chromomycosis and phaeomycotic abscess	0.644	0.356	0.000
B42 Sporotrichosis	0.644	0.356	0.000
B41 Paracoccidioidomycosis	0.644	0.356	0.000
B40 Blastomycosis	0.644	0.356	0.000
B39 Histoplasmosis	0.644	0.356	0.000
B38 Coccidioidomycosis	0.644	0.356	0.000
B36 Other superficial mycoses	0.644	0.356	0.000
S61 Open wound of wrist and hand	0.644	0.356	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.643	0.357	0.000
J18.9 Pneumonia, unspecified	0.642	0.358	0.000
M19.0 Primary arthrosis of other joints	0.641	0.359	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.641	0.359	0.000
M24.18 Other articular cartilage disorders (Other)	0.641	0.359	0.000
M24.14 Other articular cartilage disorders (Hand)	0.641	0.359	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.641	0.359	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.641	0.359	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.640	0.360	0.000
T91 Sequelae of injuries of neck and trunk	0.640	0.360	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.640	0.360	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.640	0.360	0.000
B35 Dermatophytosis	0.639	0.361	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.639	0.361	0.000
H90.5 Sensorineural hearing loss, unspecified	0.636	0.364	0.000
J95-J99 Other diseases of the respiratory system	0.636	0.364	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.635	0.365	0.000
Y42.7 Androgens and anabolic congeners	0.634	0.366	0.000
M43 Other deforming dorsopathies	0.633	0.367	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.632	0.368	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.632	0.368	0.000
D73 Diseases of spleen	0.631	0.369	0.000
S62 Fracture at wrist and hand level	0.630	0.370	0.000
G47 Sleep disorders	0.630	0.370	0.000
Y57.8 Other drugs and medicaments	0.629	0.371	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.629	0.371	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.629	0.371	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.629	0.371	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.629	0.371	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.629	0.371	0.000
G63.1 Polyneuropathy in neoplastic disease	0.629	0.371	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.629	0.371	0.000
D68.0 Von Willebrand's disease	0.629	0.371	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.628	0.372	0.000
M87 Osteonecrosis	0.628	0.372	0.000
D68.2 Hereditary deficiency of other clotting factors	0.628	0.372	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.627	0.372	0.000
M54 Dorsalgia	0.628	0.372	0.000
M23.1 Discoid meniscus (congenital)	0.627	0.373	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.627	0.373	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.625	0.375	0.000
Y45.5 4-Aminophenol derivatives	0.624	0.376	0.000
Y45.4 Antirheumatics	0.624	0.376	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.624	0.376	0.000
M79.5 Residual foreign body in soft tissue	0.623	0.376	0.000
D69.0 Allergic purpura	0.623	0.377	0.000
M17.5 Other secondary gonarthrosis	0.622	0.378	0.000
Y57.9 Drug or medicament, unspecified	0.622	0.378	0.000
M16.3 Other dysplastic coxarthrosis	0.622	0.378	0.000
S42.01 Fracture of clavicle (open)	0.621	0.379	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.621	0.379	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.621	0.379	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.621	0.379	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.621	0.379	0.000
M79.1 Myalgia	0.620	0.379	0.000
T20 Burn and corrosion of head and neck	0.620	0.379	0.000
H90.3 Sensorineural hearing loss, bilateral	0.620	0.380	0.000
W46 Contact with hypodermic needle	0.619	0.380	0.000
W45 Foreign body or object entering through skin	0.619	0.380	0.000
W43 Exposure to vibration	0.619	0.380	0.000
W42 Exposure to noise	0.619	0.380	0.000
W41 Exposure to high-pressure jet	0.619	0.380	0.000
W40 Explosion of other materials	0.619	0.380	0.000
W39 Discharge of firework	0.619	0.380	0.000
W38 Explosion and rupture of other specified pressurised devices	0.619	0.380	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.619	0.380	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations