TreeWAS – Variant ID: rs117914579

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	1.000	0.000	0.000
A30-A49 Other bacterial diseases	1.000	0.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001	0.000
A41 Other septicaemia	0.997	0.003	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003	0.000
M20.1 Hallux valgus (acquired)	0.996	0.004	0.000
Chapter II Neoplasms	0.996	0.004	0.000
M20-M25 Other joint disorders	0.995	0.005	0.000
M20 Acquired deformities of fingers and toes	0.994	0.006	0.000
Chapter V Mental and behavioural disorders	0.988	0.012	0.000
B95-B98 Bacterial, viral and other infectious agents	0.988	0.012	0.000
A41.9 Septicaemia, unspecified	0.987	0.013	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.985	0.015	0.000
O60-O75 Complications of labour and delivery	0.982	0.018	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.982	0.018	0.000
C15-C26 Malignant neoplasms of digestive organs	0.980	0.020	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.979	0.021	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.976	0.024	0.000
E70-E90 Metabolic disorders	0.968	0.032	0.000
O20 Haemorrhage in early pregnancy	0.960	0.040	0.000
M80-M85 Disorders of bone density and structure	0.959	0.041	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.956	0.044	0.000
E86 Volume depletion	0.950	0.050	0.000
E83 Disorders of mineral metabolism	0.948	0.052	0.000
C25 Malignant neoplasm of pancreas	0.946	0.054	0.000
C34 Malignant neoplasm of bronchus and lung	0.928	0.072	0.000
Chapter VII Diseases of the eye and adnexa	0.925	0.075	0.000
A49 Bacterial infection of unspecified site	0.925	0.075	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.914	0.086	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.907	0.093	0.000
C34.9 Bronchus or lung, unspecified	0.907	0.093	0.000
C20 Malignant neoplasm of rectum	0.904	0.096	0.000
O20.0 Threatened abortion	0.902	0.098	0.000
C25.9 Pancreas, unspecified	0.897	0.103	0.000
F30-F39 Mood [affective] disorders	0.893	0.107	0.000
A40 Streptococcal septicaemia	0.882	0.118	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.882	0.118	0.000
Chapter VI Diseases of the nervous system	0.880	0.120	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.876	0.124	0.000
E83.5 Disorders of calcium metabolism	0.875	0.125	0.000
H55-H59 Other disorders of eye and adnexa	0.875	0.125	0.000
E83.4 Disorders of magnesium metabolism	0.871	0.129	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.869	0.131	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.867	0.133	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.866	0.134	0.000
Chapter XXII Codes for special purposes	0.860	0.140	0.000
D00-D09 In situ neoplasms	0.855	0.145	0.000
C45 Mesothelioma	0.851	0.149	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.850	0.150	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.850	0.150	0.000
O70 Perineal laceration during delivery	0.849	0.151	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.849	0.151	0.000
O72 Postpartum haemorrhage	0.848	0.152	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.847	0.153	0.000
M84 Disorders of continuity of bone	0.845	0.155	0.000
M20.0 Deformity of finger(s)	0.844	0.156	0.000
M80 Osteoporosis with pathological fracture	0.842	0.158	0.000
F99-F99 Unspecified mental disorder	0.840	0.160	0.000
G90-G99 Other disorders of the nervous system	0.838	0.162	0.000
M91-M94 Chondropathies	0.838	0.162	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.837	0.163	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.835	0.165	0.000
Chapter X Diseases of the respiratory system	0.834	0.166	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.827	0.173	0.000
A49.8 Other bacterial infections of unspecified site	0.823	0.177	0.000
E40-E46 Malnutrition	0.822	0.178	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.821	0.179	0.000
C25.0 Head of pancreas	0.817	0.183	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.813	0.187	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.809	0.191	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.809	0.191	0.000
Chapter VIII Diseases of the ear and mastoid process	0.808	0.192	0.000
C15 Malignant neoplasm of oesophagus	0.803	0.197	0.000
D50-D53 Nutritional anaemias	0.799	0.201	0.000
O63 Long labour	0.799	0.201	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.798	0.202	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.797	0.203	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.795	0.205	0.000
Chapter XX External causes of morbidity and mortality	0.790	0.210	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.786	0.214	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.785	0.215	0.000
M25 Other joint disorders, not elsewhere classified	0.782	0.218	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.782	0.218	0.000
A46 Erysipelas	0.780	0.220	0.000
B65-B83 Helminthiases	0.779	0.221	0.000
A41.8 Other specified septicaemia	0.779	0.221	0.000
F60-F69 Disorders of adult personality and behaviour	0.779	0.221	0.000
M70-M79 Other soft tissue disorders	0.778	0.222	0.000
M86-M90 Other osteopathies	0.777	0.223	0.000
H57 Other disorders of eye and adnexa	0.777	0.223	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.777	0.223	0.000
C45.0 Mesothelioma of pleura	0.777	0.223	0.000
G93 Other disorders of brain	0.774	0.226	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.774	0.226	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.772	0.228	0.000
C34.3 Lower lobe, bronchus or lung	0.770	0.230	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.769	0.231	0.000
D50 Iron deficiency anaemia	0.768	0.232	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.767	0.233	0.000
C17 Malignant neoplasm of small intestine	0.767	0.233	0.000
J90-J94 Other diseases of pleura	0.767	0.233	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.761	0.239	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.759	0.241	0.000
O61 Failed induction of labour	0.759	0.241	0.000
O71 Other obstetric trauma	0.758	0.241	0.000
O20.8 Other haemorrhage in early pregnancy	0.756	0.244	0.000
E50-E64 Other nutritional deficiencies	0.756	0.244	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.754	0.246	0.000
H02 Other disorders of eyelid	0.753	0.247	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.753	0.247	0.000
M81 Osteoporosis without pathological fracture	0.752	0.248	0.000
G20-G26 Extrapyramidal and movement disorders	0.752	0.248	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.752	0.248	0.000
F03 Unspecified dementia	0.751	0.249	0.000
O21 Excessive vomiting in pregnancy	0.750	0.250	0.000
M21 Other acquired deformities of limbs	0.749	0.250	0.000
A40.8 Other streptococcal septicaemia	0.748	0.252	0.000
F32 Depressive episode	0.748	0.252	0.000
R29.6 Tendency to fall, not elsewhere classified	0.747	0.253	0.000
O80-O84 Delivery	0.746	0.254	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.745	0.255	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.744	0.256	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.743	0.257	0.000
B35-B49 Mycoses	0.741	0.259	0.000
R42 Dizziness and giddiness	0.740	0.260	0.000
O00-O08 Pregnancy with abortive outcome	0.740	0.260	0.000
C16 Malignant neoplasm of stomach	0.739	0.261	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.738	0.262	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.736	0.264	0.000
F99 Mental disorder, not otherwise specified	0.734	0.266	0.000
M85 Other disorders of bone density and structure	0.733	0.267	0.000
F43 Reaction to severe stress, and adjustment disorders	0.733	0.267	0.000
F31 Bipolar affective disorder	0.733	0.267	0.000
M20.5 Other deformities of toe(s) (acquired)	0.731	0.269	0.000
O23 Infections of genito-urinary tract in pregnancy	0.731	0.269	0.000
M72 Fibroblastic disorders	0.730	0.270	0.000
D50.8 Other iron deficiency anaemias	0.730	0.270	0.000
M82 Osteoporosis in diseases classified elsewhere	0.728	0.272	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.728	0.272	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.727	0.273	0.000
A40.0 Septicaemia due to streptococcus, group A	0.725	0.275	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.724	0.276	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.724	0.276	0.000
O70.1 Second degree perineal laceration during delivery	0.724	0.276	0.000
A49.1 Streptococcal infection, unspecified	0.724	0.276	0.000
O16 Unspecified maternal hypertension	0.724	0.276	0.000
E83.3 Disorders of phosphorus metabolism	0.722	0.278	0.000
E83.1 Disorders of iron metabolism	0.721	0.279	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.721	0.279	0.000
E20-E35 Disorders of other endocrine glands	0.719	0.281	0.000
J30-J39 Other diseases of upper respiratory tract	0.718	0.282	0.000
M20.3 Other deformity of hallux (acquired)	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
B99-B99 Other infectious diseases	0.717	0.283	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.717	0.283	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.717	0.283	0.000
B50-B64 Protozoal diseases	0.717	0.283	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.717	0.283	0.000
B15-B19 Viral hepatitis	0.717	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.717	0.283	0.000
A80-A89 Viral infections of the central nervous system	0.717	0.283	0.000
A75-A79 Rickettsioses	0.717	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.717	0.283	0.000
A65-A69 Other spirochaetal diseases	0.717	0.283	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.717	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.717	0.283	0.000
A15-A19 Tuberculosis	0.717	0.283	0.000
O72.1 Other immediate postpartum haemorrhage	0.717	0.283	0.000
H02.8 Other specified disorders of eyelid	0.717	0.283	0.000
A48 Other bacterial diseases, not elsewhere classified	0.717	0.283	0.000
A44 Bartonellosis	0.717	0.283	0.000
A43 Nocardiosis	0.717	0.283	0.000
A42 Actinomycosis	0.717	0.283	0.000
A39 Meningococcal infection	0.717	0.283	0.000
A37 Whooping cough	0.717	0.283	0.000
A36 Diphtheria	0.717	0.283	0.000
A32 Listeriosis	0.717	0.283	0.000
A31 Infection due to other mycobacteria	0.717	0.283	0.000
A30 Leprosy [Hansen's disease]	0.717	0.283	0.000
A38 Scarlet fever	0.717	0.283	0.000
A35 Other tetanus	0.717	0.283	0.000
A34 Obstetrical tetanus	0.717	0.283	0.000
A33 Tetanus neonatorum	0.717	0.283	0.000
O85-O92 Complications predominantly related to the puerperium	0.717	0.283	0.000
O24 Diabetes mellitus in pregnancy	0.716	0.284	0.000
G70-G73 Diseases of myoneural junction and muscle	0.715	0.285	0.000
A41.4 Septicaemia due to anaerobes	0.715	0.285	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.715	0.285	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.715	0.285	0.000
M60-M63 Disorders of muscles	0.715	0.285	0.000
M00-M03 Infectious arthropathies	0.715	0.285	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.714	0.286	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.713	0.287	0.000
M34 Systemic sclerosis	0.713	0.287	0.000
M33 Dermatopolymyositis	0.713	0.287	0.000
M32 Systemic lupus erythematosus	0.713	0.287	0.000
M30 Polyarteritis nodosa and related conditions	0.713	0.287	0.000
M22 Disorders of patella	0.713	0.287	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.713	0.287	0.000
L89 Decubitus ulcer	0.712	0.288	0.000
A49.0 Staphylococcal infection, unspecified	0.711	0.289	0.000
D04 Carcinoma in situ of skin	0.709	0.290	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.709	0.291	0.000
F80-F89 Disorders of psychological development	0.709	0.291	0.000
F70-F79 Mental retardation	0.709	0.291	0.000
E46 Unspecified protein-energy malnutrition	0.707	0.292	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.706	0.294	0.000
F33 Recurrent depressive disorder	0.706	0.294	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.706	0.294	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.706	0.294	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.706	0.294	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.706	0.294	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.706	0.294	0.000
C45.9 Mesothelioma, unspecified	0.705	0.295	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.705	0.295	0.000
O74 Complications of anaesthesia during labour and delivery	0.704	0.296	0.000
O73 Retained placenta and membranes, without haemorrhage	0.704	0.296	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.704	0.296	0.000
O66 Other obstructed labour	0.704	0.296	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.704	0.296	0.000
O62 Abnormalities of forces of labour	0.704	0.296	0.000
O60 Preterm delivery	0.704	0.296	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.704	0.296	0.000
R40 Somnolence, stupor and coma	0.704	0.296	0.000
A49.9 Bacterial infection, unspecified	0.704	0.296	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.704	0.296	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.702	0.298	0.000
C21 Malignant neoplasm of anus and anal canal	0.702	0.298	0.000
C23 Malignant neoplasm of gallbladder	0.702	0.298	0.000
O29 Complications of anaesthesia during pregnancy	0.702	0.298	0.000
O28 Abnormal findings on antenatal screening of mother	0.702	0.298	0.000
O22 Venous complications in pregnancy	0.702	0.298	0.000
O25 Malnutrition in pregnancy	0.702	0.298	0.000
F20 Schizophrenia	0.701	0.299	0.000
J90 Pleural effusion, not elsewhere classified	0.699	0.301	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.699	0.301	0.000
E88 Other metabolic disorders	0.699	0.301	0.000
Q60-Q64 Congenital malformations of the urinary system	0.698	0.302	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.698	0.302	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.696	0.303	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.696	0.304	0.000
B25-B34 Other viral diseases	0.696	0.304	0.000
H20 Iridocyclitis	0.695	0.305	0.000
E85 Amyloidosis	0.694	0.306	0.000
E84 Cystic fibrosis	0.694	0.306	0.000
E79 Disorders of purine and pyrimidine metabolism	0.694	0.306	0.000
E77 Disorders of glycoprotein metabolism	0.694	0.306	0.000
E76 Disorders of glycosaminoglycan metabolism	0.694	0.306	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.694	0.306	0.000
E74 Other disorders of carbohydrate metabolism	0.694	0.306	0.000
E73 Lactose intolerance	0.694	0.306	0.000
E72 Other disorders of amino-acid metabolism	0.694	0.306	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.694	0.306	0.000
E70 Disorders of aromatic amino-acid metabolism	0.694	0.306	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.694	0.306	0.000
Q80-Q89 Other congenital malformations	0.694	0.306	0.000
F29 Unspecified nonorganic psychosis	0.692	0.308	0.000
C07 Malignant neoplasm of parotid gland	0.692	0.308	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.692	0.308	0.000
M25.7 Osteophyte	0.691	0.309	0.000
H65-H75 Diseases of middle ear and mastoid	0.690	0.310	0.000
C09 Malignant neoplasm of tonsil	0.690	0.310	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.690	0.310	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.688	0.312	0.000
H02.4 Ptosis of eyelid	0.688	0.312	0.000
M83 Adult osteomalacia	0.688	0.312	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.687	0.313	0.000
E00-E07 Disorders of thyroid gland	0.686	0.313	0.001
Chapter XXI Factors influencing health status and contact with health services	0.687	0.313	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.686	0.314	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.686	0.314	0.000
C32 Malignant neoplasm of larynx	0.686	0.314	0.000
C31 Malignant neoplasm of accessory sinuses	0.686	0.314	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.686	0.314	0.000
C37 Malignant neoplasm of thymus	0.686	0.314	0.000
C33 Malignant neoplasm of trachea	0.686	0.314	0.000
M24 Other specific joint derangements	0.686	0.314	0.000
D03 Melanoma in situ	0.685	0.315	0.000
G93.6 Cerebral oedema	0.685	0.315	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.684	0.316	0.000
D50.9 Iron deficiency anaemia, unspecified	0.683	0.317	0.000
O63.1 Prolonged second stage (of labour)	0.681	0.319	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.680	0.320	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.679	0.321	0.000
E83.8 Other disorders of mineral metabolism	0.679	0.321	0.000
E83.2 Disorders of zinc metabolism	0.679	0.321	0.000
E83.0 Disorders of copper metabolism	0.679	0.321	0.000
C25.8 Overlapping lesion of pancreas	0.679	0.321	0.000
C25.7 Other parts of pancreas	0.679	0.321	0.000
C25.4 Endocrine pancreas	0.679	0.321	0.000
C25.3 Pancreatic duct	0.679	0.321	0.000
C25.2 Tail of pancreas	0.679	0.321	0.000
C25.1 Body of pancreas	0.679	0.321	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.678	0.322	0.000
C34.0 Main bronchus	0.678	0.322	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.678	0.322	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.678	0.322	0.000
M93 Other osteochondropathies	0.678	0.322	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.677	0.323	0.000
R41.0 Disorientation, unspecified	0.677	0.323	0.000
F25 Schizoaffective disorders	0.677	0.323	0.000
H10-H13 Disorders of conjunctiva	0.676	0.324	0.000
F42 Obsessive-compulsive disorder	0.675	0.325	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.675	0.325	0.000
E65-E68 Obesity and other hyperalimentation	0.675	0.325	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.671	0.328	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.671	0.329	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.671	0.329	0.000
M94 Other disorders of cartilage	0.670	0.330	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.670	0.330	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.668	0.331	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.668	0.332	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.667	0.333	0.000
O70.0 First degree perineal laceration during delivery	0.667	0.333	0.000
U80 Agent resistant to penicillin and related antibiotics	0.667	0.333	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.667	0.333	0.000
C34.8 Overlapping lesion of bronchus and lung	0.665	0.334	0.000
C34.2 Middle lobe, bronchus or lung	0.665	0.334	0.000
H57.0 Anomalies of pupillary function	0.664	0.336	0.000
A00-A09 Intestinal infectious diseases	0.663	0.336	0.000
A49.3 Mycoplasma infection, unspecified	0.663	0.337	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.663	0.337	0.000
M35 Other systemic involvement of connective tissue	0.662	0.337	0.000
L89.1 Stage II decubitus ulcer	0.662	0.338	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.660	0.339	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.659	0.341	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.658	0.342	0.000
D07.5 Prostate	0.657	0.343	0.000
C15.5 Lower third of oesophagus	0.657	0.343	0.000
J92 Pleural plaque	0.657	0.343	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.655	0.345	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.655	0.345	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.655	0.345	0.000
C46 Kaposi's sarcoma	0.655	0.345	0.000
Q50-Q56 Congenital malformations of genital organs	0.655	0.345	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.653	0.347	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.652	0.348	0.000
L90 Atrophic disorders of skin	0.652	0.348	0.000
F40 Phobic anxiety disorders	0.651	0.349	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.650	0.349	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.650	0.349	0.000
Q35-Q37 Cleft lip and cleft palate	0.650	0.349	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.650	0.349	0.000
Q00-Q07 Congenital malformations of the nervous system	0.650	0.349	0.000
D80-D89 Certain disorders involving the immune mechanism	0.650	0.349	0.000
R25 Abnormal involuntary movements	0.650	0.350	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.650	0.350	0.000
G93.3 Postviral fatigue syndrome	0.648	0.352	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.648	0.352	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.648	0.352	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.646	0.354	0.000
F22 Persistent delusional disorders	0.646	0.354	0.000
M31 Other necrotising vasculopathies	0.645	0.355	0.000
H90-H95 Other disorders of ear	0.644	0.356	0.000
J81 Pulmonary oedema	0.642	0.357	0.000
G30-G32 Other degenerative diseases of the nervous system	0.641	0.359	0.000
C85.1 B-cell lymphoma, unspecified	0.641	0.359	0.000
F38 Other mood [affective] disorders	0.640	0.359	0.000
F34 Persistent mood [affective] disorders	0.640	0.359	0.000
F30 Manic episode	0.640	0.359	0.000
F39 Unspecified mood [affective] disorder	0.640	0.359	0.000
D55-D59 Haemolytic anaemias	0.640	0.360	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.639	0.361	0.000
H25-H28 Disorders of lens	0.637	0.363	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.636	0.363	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.636	0.364	0.000
H40-H42 Glaucoma	0.636	0.364	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.635	0.365	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.634	0.366	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.633	0.367	0.000
A40.9 Streptococcal septicaemia, unspecified	0.632	0.368	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.632	0.368	0.000
A40.2 Septicaemia due to streptococcus, group D	0.632	0.368	0.000
A40.1 Septicaemia due to streptococcus, group B	0.632	0.368	0.000
O72.0 Third-stage haemorrhage	0.632	0.368	0.000
W00-W19 Falls	0.632	0.368	0.000
R47-R49 Symptoms and signs involving speech and voice	0.631	0.369	0.000
R27 Other lack of coordination	0.631	0.369	0.000
F43.2 Adjustment disorders	0.631	0.369	0.000
D09 Carcinoma in situ of other and unspecified sites	0.630	0.370	0.000
O43 Placental disorders	0.629	0.371	0.000
S50-S59 Injuries to the elbow and forearm	0.629	0.371	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.629	0.371	0.000
F60 Specific personality disorders	0.629	0.371	0.000
H55 Nystagmus and other irregular eye movements	0.627	0.372	0.000
Q21 Congenital malformations of cardiac septa	0.627	0.373	0.000
O40 Polyhydramnios	0.625	0.375	0.000
G24 Dystonia	0.625	0.375	0.000
J34 Other disorders of nose and nasal sinuses	0.625	0.375	0.000
O63.9 Long labour, unspecified	0.625	0.375	0.000
J33 Nasal polyp	0.624	0.376	0.000
F23 Acute and transient psychotic disorders	0.623	0.377	0.000
F28 Other nonorganic psychotic disorders	0.623	0.377	0.000
F24 Induced delusional disorder	0.623	0.377	0.000
F21 Schizotypal disorder	0.623	0.377	0.000
H20.9 Iridocyclitis, unspecified	0.622	0.377	0.000
B80 Enterobiasis	0.621	0.379	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.620	0.380	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.619	0.381	0.000
S80-S89 Injuries to the knee and lower leg	0.618	0.382	0.000
M86 Osteomyelitis	0.617	0.383	0.000
C16.0 Cardia	0.616	0.384	0.000
S70-S79 Injuries to the hip and thigh	0.616	0.384	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.616	0.384	0.000
G95 Other diseases of spinal cord	0.616	0.384	0.000
M65-M68 Disorders of synovium and tendon	0.616	0.384	0.000
O47 False labour	0.615	0.385	0.000
M21.1 Varus deformity, not elsewhere classified	0.615	0.385	0.000
C17.2 Ileum	0.614	0.386	0.000
C88 Malignant immunoproliferative diseases	0.614	0.386	0.000
H43-H45 Disorders of vitreous body and globe	0.614	0.386	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.613	0.387	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.613	0.387	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.613	0.387	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.613	0.387	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.613	0.387	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.612	0.388	0.000
M81.4 Drug-induced osteoporosis	0.612	0.388	0.000
H01 Other inflammation of eyelid	0.612	0.388	0.000
H57.1 Ocular pain	0.611	0.389	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.610	0.389	0.000
C45.7 Mesothelioma of other sites	0.610	0.390	0.000
C45.2 Mesothelioma of pericardium	0.610	0.390	0.000
C45.1 Mesothelioma of peritoneum	0.610	0.390	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.610	0.390	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.610	0.390	0.000
M84.0 Malunion of fracture	0.610	0.390	0.000
H72 Perforation of tympanic membrane	0.610	0.390	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.610	0.390	0.000
F48 Other neurotic disorders	0.609	0.390	0.000
F44 Dissociative [conversion] disorders	0.609	0.390	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.609	0.391	0.000
C13 Malignant neoplasm of hypopharynx	0.609	0.391	0.000
C11 Malignant neoplasm of nasopharynx	0.609	0.391	0.000
C10 Malignant neoplasm of oropharynx	0.609	0.391	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.609	0.391	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.609	0.391	0.000
C05 Malignant neoplasm of palate	0.609	0.391	0.000
C04 Malignant neoplasm of floor of mouth	0.609	0.391	0.000
C03 Malignant neoplasm of gum	0.609	0.391	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.609	0.391	0.000
C00 Malignant neoplasm of lip	0.609	0.391	0.000
C12 Malignant neoplasm of pyriform sinus	0.609	0.391	0.000
C01 Malignant neoplasm of base of tongue	0.609	0.391	0.000
O70.9 Perineal laceration during delivery, unspecified	0.609	0.391	0.000
O70.3 Fourth degree perineal laceration during delivery	0.609	0.391	0.000
O70.2 Third degree perineal laceration during delivery	0.609	0.391	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.609	0.391	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.609	0.391	0.000
F02 Dementia in other diseases classified elsewhere	0.609	0.391	0.000
F09 Unspecified organic or symptomatic mental disorder	0.609	0.391	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.609	0.391	0.000
C64-C68 Malignant neoplasms of urinary tract	0.608	0.392	0.000
M23 Internal derangement of knee	0.608	0.392	0.000
O72.3 Postpartum coagulation defects	0.608	0.392	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.607	0.392	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.607	0.393	0.000
G25 Other extrapyramidal and movement disorders	0.606	0.393	0.000
C92 Myeloid leukaemia	0.606	0.394	0.000
S90-S99 Injuries to the ankle and foot	0.606	0.394	0.000
M84.9 Disorder of continuity of bone, unspecified	0.606	0.394	0.000
M84.8 Other disorders of continuity of bone	0.606	0.394	0.000
M84.4 Pathological fracture, not elsewhere classified	0.606	0.394	0.000
M84.3 Stress fracture, not elsewhere classified	0.606	0.394	0.000
M84.2 Delayed union of fracture	0.606	0.394	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.605	0.395	0.000
C15.9 Oesophagus, unspecified	0.605	0.395	0.000
D46 Myelodysplastic syndromes	0.605	0.395	0.000
M80.8 Other osteoporosis with pathological fracture	0.604	0.396	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.604	0.396	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.604	0.396	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.604	0.396	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.604	0.396	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.604	0.396	0.000
S20-S29 Injuries to the thorax	0.603	0.397	0.000
O44 Placenta praevia	0.603	0.397	0.000
M25.77 Osteophyte (Ankle and foot)	0.602	0.398	0.000
S10-S19 Injuries to the neck	0.601	0.399	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.601	0.399	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.601	0.399	0.000
G96 Other disorders of central nervous system	0.601	0.399	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.601	0.399	0.000
G90 Disorders of autonomic nervous system	0.601	0.399	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.601	0.399	0.000
G92 Toxic encephalopathy	0.601	0.399	0.000
F32.9 Depressive episode, unspecified	0.601	0.399	0.000
M92 Other juvenile osteochondrosis	0.601	0.399	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.601	0.399	0.000
O15 Eclampsia	0.600	0.400	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.600	0.400	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.600	0.400	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.600	0.400	0.000
J60-J70 Lung diseases due to external agents	0.600	0.400	0.000
R44.3 Hallucinations, unspecified	0.599	0.401	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.599	0.401	0.000
O61.0 Failed medical induction of labour	0.599	0.401	0.000
X20-X29 Contact with venomous animals and plants	0.599	0.401	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.598	0.402	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations