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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117929870
log Bayes Factor = 16.9839
Chromosome 12   position 108,524,849  (GRCh37) Explore rs117929870 on Ensembl!
Variant rs117929870 is part of Cluster X0021

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N81 Female genital prolapse
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
M54 Dorsalgia
0.999 0.001 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Z96 Presence of other functional implants
0.996 0.004 0.000
N81.2 Incomplete uterovaginal prolapse
0.995 0.005 0.000
Z96.6 Presence of orthopaedic joint implants
0.993 0.007 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.992 0.008 0.000
N81.1 Cystocele
0.991 0.009 0.000
M17 Gonarthrosis [arthrosis of knee]
0.986 0.014 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.983 0.017 0.000
Z96.1 Presence of intraocular lens
0.982 0.018 0.000
N17-N19 Renal failure
0.980 0.020 0.000
S80-S89 Injuries to the knee and lower leg
0.980 0.020 0.000
N81.6 Rectocele
0.978 0.022 0.000
M05-M14 Inflammatory polyarthropathies
0.978 0.022 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.977 0.023 0.000
S00-S09 Injuries to the head
0.973 0.027 0.000
N18 Chronic renal failure
0.971 0.029 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.962 0.038 0.000
M17.0 Primary gonarthrosis, bilateral
0.958 0.042 0.000
S60-S69 Injuries to the wrist and hand
0.957 0.043 0.000
M19 Other arthrosis
0.952 0.048 0.000
M54.4 Lumbago with sciatica
0.948 0.052 0.000
M18 Arthrosis of first carpometacarpal joint
0.948 0.052 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.939 0.061 0.000
S50-S59 Injuries to the elbow and forearm
0.936 0.064 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.932 0.068 0.000
N18.9 Chronic renal failure, unspecified
0.932 0.068 0.000
M54.3 Sciatica
0.931 0.069 0.000
O60-O75 Complications of labour and delivery
0.931 0.069 0.000
M20-M25 Other joint disorders
0.924 0.076 0.000
M19.9 Arthrosis, unspecified
0.922 0.078 0.000
S01 Open wound of head
0.919 0.081 0.000
Z92 Personal history of medical treatment
0.915 0.085 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.909 0.091 0.000
M54.2 Cervicalgia
0.908 0.092 0.000
S01.8 Open wound of other parts of head
0.908 0.092 0.000
S80 Superficial injury of lower leg
0.907 0.093 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.903 0.097 0.000
M51 Other intervertebral disk disorders
0.901 0.099 0.000
Z50 Care involving use of rehabilitation procedures
0.901 0.099 0.000
N40-N51 Diseases of male genital organs
0.896 0.104 0.000
M17.1 Other primary gonarthrosis
0.894 0.106 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.892 0.108 0.000
S62 Fracture at wrist and hand level
0.892 0.108 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.889 0.111 0.000
O48 Prolonged pregnancy
0.888 0.112 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.883 0.117 0.000
Chapter II Neoplasms
0.882 0.118 0.000
M06 Other rheumatoid arthritis
0.882 0.118 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.879 0.121 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.879 0.121 0.000
S82 Fracture of lower leg, including ankle
0.877 0.123 0.000
M13 Other arthritis
0.876 0.124 0.000
M54.9 Dorsalgia, unspecified
0.875 0.125 0.000
N81.9 Female genital prolapse, unspecified
0.874 0.126 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.872 0.128 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.872 0.128 0.000
M07 Psoriatic and enteropathic arthropathies
0.871 0.129 0.000
M54.5 Low back pain
0.869 0.131 0.000
N18.2 Chronic kidney disease, stage 2
0.868 0.132 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.867 0.133 0.000
M54.39 Sciatica (Site unspecified)
0.865 0.135 0.000
S90-S99 Injuries to the ankle and foot
0.862 0.138 0.000
N43 Hydrocele and spermatocele
0.861 0.139 0.000
Z50.1 Other physical therapy
0.857 0.143 0.000
O41 Other disorders of amniotic fluid and membranes
0.852 0.148 0.000
S51 Open wound of forearm
0.849 0.151 0.000
M54.1 Radiculopathy
0.848 0.152 0.000
M54.22 Cervicalgia (Cervical region)
0.844 0.156 0.000
S02 Fracture of skull and facial bones
0.843 0.157 0.000
N48 Other disorders of penis
0.841 0.159 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.841 0.159 0.000
S62.6 Fracture of other finger
0.839 0.161 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.836 0.164 0.000
Z90.8 Acquired absence of other organs
0.836 0.164 0.000
N43.3 Hydrocele, unspecified
0.835 0.165 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.834 0.166 0.000
T66-T78 Other and unspecified effects of external causes
0.834 0.166 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.833 0.167 0.000
M23 Internal derangement of knee
0.831 0.169 0.000
W00-W19 Falls
0.830 0.170 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.829 0.171 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.829 0.171 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.824 0.176 0.000
W20-W49 Exposure to inanimate mechanical forces
0.823 0.177 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.823 0.177 0.000
C51-C58 Malignant neoplasms of female genital organs
0.823 0.177 0.000
Z98 Other postsurgical states
0.820 0.180 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.818 0.182 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.816 0.184 0.000
S06 Intracranial injury
0.811 0.189 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.809 0.191 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.808 0.192 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.808 0.192 0.000
S62.61 Fracture of other finger (open)
0.808 0.192 0.000
O00-O08 Pregnancy with abortive outcome
0.808 0.192 0.000
N18.3 Chronic kidney disease, stage 3
0.807 0.193 0.000
Chapter VII Diseases of the eye and adnexa
0.807 0.193 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.805 0.195 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.804 0.196 0.000
O43 Placental disorders
0.802 0.198 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.802 0.198 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.801 0.199 0.000
Z90.3 Acquired absence of part of stomach
0.801 0.199 0.000
N17 Acute renal failure
0.799 0.201 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.798 0.202 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.796 0.204 0.000
C15-C26 Malignant neoplasms of digestive organs
0.795 0.205 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.795 0.205 0.000
M07.3 Other psoriatic arthropathies
0.794 0.206 0.000
O73 Retained placenta and membranes, without haemorrhage
0.793 0.207 0.000
M21 Other acquired deformities of limbs
0.793 0.207 0.000
N81.3 Complete uterovaginal prolapse
0.792 0.208 0.000
X60-X84 Intentional self-harm
0.791 0.209 0.000
N97 Female infertility
0.790 0.210 0.000
N18.5 Chronic kidney disease, stage 5
0.790 0.210 0.000
N81.4 Uterovaginal prolapse, unspecified
0.789 0.211 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.789 0.211 0.000
S82.0 Fracture of patella
0.787 0.213 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.786 0.214 0.000
S20-S29 Injuries to the thorax
0.786 0.214 0.000
M25 Other joint disorders, not elsewhere classified
0.781 0.219 0.000
O36 Maternal care for other known or suspected foetal problems
0.781 0.219 0.000
M51.2 Other specified intervertebral disk displacement
0.781 0.219 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.777 0.223 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.777 0.223 0.000
S50 Superficial injury of forearm
0.777 0.223 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.776 0.224 0.000
S40-S49 Injuries to the shoulder and upper arm
0.775 0.225 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.775 0.225 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.775 0.225 0.000
Z50.8 Care involving use of rehabilitation procedures
0.773 0.227 0.000
Z43 Attention to artificial openings
0.773 0.227 0.000
O21 Excessive vomiting in pregnancy
0.772 0.228 0.000
M06.9 Rheumatoid arthritis, unspecified
0.769 0.231 0.000
Q60-Q64 Congenital malformations of the urinary system
0.767 0.233 0.000
M13.9 Arthritis, unspecified
0.767 0.233 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.767 0.233 0.000
S05 Injury of eye and orbit
0.766 0.233 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.766 0.234 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.764 0.236 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.763 0.237 0.000
Z90.2 Acquired absence of lung [part of]
0.763 0.237 0.000
O41.0 Oligohydramnios
0.762 0.238 0.000
O62 Abnormalities of forces of labour
0.761 0.239 0.000
C15 Malignant neoplasm of oesophagus
0.760 0.240 0.000
M54.59 Low back pain (Site unspecified)
0.759 0.241 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.758 0.242 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.758 0.242 0.000
Z90.7 Acquired absence of genital organ(s)
0.758 0.242 0.000
S80.9 Superficial injury of lower leg, unspecified
0.757 0.243 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.756 0.244 0.000
N42 Other disorders of prostate
0.756 0.244 0.000
I60-I69 Cerebrovascular diseases
0.754 0.246 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.753 0.247 0.000
N82 Fistulae involving female genital tract
0.752 0.247 0.000
N85.4 Malposition of uterus
0.752 0.248 0.000
N80 Endometriosis
0.752 0.248 0.000
Chapter V Mental and behavioural disorders
0.750 0.250 0.000
M31 Other necrotising vasculopathies
0.750 0.250 0.000
M23.3 Other meniscus derangements
0.750 0.250 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.749 0.251 0.000
Chapter IX Diseases of the circulatory system
0.747 0.253 0.000
N48.1 Balanoposthitis
0.747 0.253 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.747 0.253 0.000
Z81 Family history of mental and behavioural disorders
0.746 0.254 0.000
S80.8 Other superficial injuries of lower leg
0.746 0.254 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.745 0.255 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.744 0.256 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.743 0.257 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.742 0.258 0.000
M86-M90 Other osteopathies
0.740 0.259 0.000
N46 Male infertility
0.739 0.261 0.000
H43-H45 Disorders of vitreous body and globe
0.739 0.261 0.000
S89 Other and unspecified injuries of lower leg
0.739 0.261 0.000
Chapter XXII Codes for special purposes
0.737 0.263 0.000
Z50.5 Speech therapy
0.737 0.263 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.736 0.264 0.000
M60-M63 Disorders of muscles
0.735 0.265 0.000
S10-S19 Injuries to the neck
0.735 0.265 0.000
M54.36 Sciatica (Lumbar region)
0.733 0.267 0.000
S51.0 Open wound of elbow
0.733 0.267 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.733 0.267 0.000
S00 Superficial injury of head
0.733 0.267 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.732 0.268 0.000
S02.1 Fracture of base of skull
0.732 0.268 0.000
M06.0 Seronegative rheumatoid arthritis
0.731 0.269 0.000
M70-M79 Other soft tissue disorders
0.731 0.269 0.000
N48.8 Other specified disorders of penis
0.730 0.270 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.729 0.271 0.000
S56 Injury of muscle and tendon at forearm level
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.728 0.272 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.726 0.274 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.726 0.274 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.726 0.274 0.000
C56 Malignant neoplasm of ovary
0.726 0.274 0.000
N89 Other noninflammatory disorders of vagina
0.725 0.275 0.000
Z96.7 Presence of other bone and tendon implants
0.725 0.275 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.725 0.275 0.000
O36.5 Maternal care for poor foetal growth
0.724 0.276 0.000
S82.2 Fracture of shaft of tibia
0.724 0.276 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.723 0.277 0.000
S82.00 Fracture of patella (closed)
0.723 0.277 0.000
Z83 Family history of other specific disorders
0.722 0.278 0.000
S51.9 Open wound of forearm, part unspecified
0.720 0.280 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.719 0.281 0.000
W10 Fall on and from stairs and steps
0.719 0.281 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.719 0.281 0.000
O63 Long labour
0.719 0.281 0.000
M65-M68 Disorders of synovium and tendon
0.719 0.281 0.000
M17.9 Gonarthrosis, unspecified
0.718 0.282 0.000
O70 Perineal laceration during delivery
0.718 0.282 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.718 0.282 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N81.0 Female urethrocele
0.717 0.283 0.000
Z90.5 Acquired absence of kidney
0.716 0.284 0.000
N98 Complications associated with artificial fertilisation
0.716 0.284 0.000
N91 Absent, scanty and rare menstruation
0.716 0.284 0.000
N96 Habitual aborter
0.716 0.284 0.000
M54.8 Other dorsalgia
0.716 0.284 0.000
M54.6 Pain in thoracic spine
0.716 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.284 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.716 0.284 0.000
M15 Polyarthrosis
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
M54.56 Low back pain (Lumbar region)
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.714 0.286 0.000
T78 Adverse effects, not elsewhere classified
0.714 0.286 0.000
Z84 Family history of other conditions
0.714 0.286 0.000
Z96.9 Presence of functional implant, unspecified
0.714 0.286 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.714 0.286 0.000
Z96.4 Presence of endocrine implants
0.714 0.286 0.000
Z96.3 Presence of artificial larynx
0.714 0.286 0.000
Z96.2 Presence of otological and audiological implants
0.714 0.286 0.000
O04 Medical abortion
0.714 0.286 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.712 0.288 0.000
S60 Superficial injury of wrist and hand
0.711 0.289 0.000
N48.6 Balanitis xerotica obliterans
0.711 0.289 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.710 0.290 0.000
O20 Haemorrhage in early pregnancy
0.710 0.290 0.000
I67 Other cerebrovascular diseases
0.709 0.291 0.000
M13.0 Polyarthritis, unspecified
0.708 0.292 0.000
Z89 Acquired absence of limb
0.707 0.292 0.000
M17.5 Other secondary gonarthrosis
0.707 0.293 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.707 0.293 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.707 0.293 0.000
Z43.3 Attention to colostomy
0.706 0.294 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
C15.5 Lower third of oesophagus
0.706 0.294 0.000
M17.3 Other posttraumatic gonarthrosis
0.705 0.295 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.705 0.295 0.000
O16 Unspecified maternal hypertension
0.705 0.295 0.000
Z52 Donors of organs and tissues
0.705 0.295 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.704 0.296 0.000
O23 Infections of genito-urinary tract in pregnancy
0.703 0.297 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.702 0.297 0.000
S88 Traumatic amputation of lower leg
0.702 0.297 0.000
S87 Crushing injury of lower leg
0.702 0.297 0.000
S86 Injury of muscle and tendon at lower leg level
0.702 0.297 0.000
S85 Injury of blood vessels at lower leg level
0.702 0.297 0.000
S84 Injury of nerves at lower leg level
0.702 0.297 0.000
C54 Malignant neoplasm of corpus uteri
0.702 0.298 0.000
M14 Arthropathies in other diseases classified elsewhere
0.701 0.299 0.000
M12 Other specific arthropathies
0.701 0.299 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.701 0.299 0.000
M08 Juvenile arthritis
0.701 0.299 0.000
Z42 Follow-up care involving plastic surgery
0.701 0.299 0.000
S81 Open wound of lower leg
0.701 0.299 0.000
O45 Premature separation of placenta [abruptio placentae]
0.700 0.299 0.000
O44 Placenta praevia
0.700 0.299 0.000
O33 Maternal care for known or suspected disproportion
0.700 0.299 0.000
O31 Complications specific to multiple gestation
0.700 0.299 0.000
O40 Polyhydramnios
0.700 0.299 0.000
S01.7 Multiple open wounds of head
0.698 0.302 0.000
S08 Traumatic amputation of part of head
0.698 0.302 0.000
S07 Crushing injury of head
0.698 0.302 0.000
S04 Injury of cranial nerves
0.698 0.302 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.698 0.302 0.000
S01.4 Open wound of cheek and temporomandibular area
0.698 0.302 0.000
Z99.1 Dependence on respirator
0.698 0.302 0.000
M05 Seropositive rheumatoid arthritis
0.697 0.302 0.000
N90.5 Atrophy of vulva
0.697 0.303 0.000
N81.8 Other female genital prolapse
0.696 0.304 0.000
N88 Other noninflammatory disorders of cervix uteri
0.696 0.304 0.000
N18.8 Other chronic renal failure
0.696 0.304 0.000
N18.1 Chronic kidney disease, stage 1
0.696 0.304 0.000
Z75 Problems related to medical facilities and other health care
0.695 0.304 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.695 0.305 0.000
O73.0 Retained placenta, without haemorrhage
0.695 0.305 0.000
C91 Lymphoid leukaemia
0.695 0.305 0.000
S62.5 Fracture of thumb
0.694 0.306 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.693 0.307 0.000
M11 Other crystal arthropathies
0.692 0.307 0.000
Q00-Q07 Congenital malformations of the nervous system
0.692 0.308 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.692 0.308 0.000
Z98.8 Other specified postsurgical states
0.692 0.308 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.691 0.309 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.691 0.309 0.000
S91 Open wound of ankle and foot
0.691 0.309 0.000
Z50.2 Alcohol rehabilitation
0.690 0.310 0.000
H43 Disorders of vitreous body
0.690 0.310 0.000
Z45 Adjustment and management of implanted device
0.690 0.310 0.000
T87 Complications peculiar to reattachment and amputation
0.689 0.310 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.689 0.310 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.688 0.312 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.688 0.312 0.000
R10 Abdominal and pelvic pain
0.687 0.313 0.000
S65 Injury of blood vessels at wrist and hand level
0.686 0.314 0.000
S20 Superficial injury of thorax
0.685 0.315 0.000
M22 Disorders of patella
0.684 0.315 0.000
S01.0 Open wound of scalp
0.683 0.316 0.000
T86 Failure and rejection of transplanted organs and tissues
0.683 0.316 0.000
M19.94 Arthrosis, unspecified (Hand)
0.683 0.317 0.000
M19.8 Other specified arthrosis
0.683 0.317 0.000
M19.2 Other secondary arthrosis
0.683 0.317 0.000
M19.98 Arthrosis, unspecified (Other)
0.682 0.318 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.682 0.318 0.000
M19.1 Posttraumatic arthrosis of other joints
0.681 0.319 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.681 0.319 0.000
C85.1 B-cell lymphoma, unspecified
0.681 0.319 0.000
N99-N99 Other disorders of the genitourinary system
0.681 0.319 0.000
W07 Fall involving chair
0.681 0.319 0.000
Z90.0 Acquired absence of part of head and neck
0.681 0.319 0.000
Q80-Q89 Other congenital malformations
0.680 0.320 0.000
W22 Striking against or struck by other objects
0.680 0.320 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.679 0.320 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.679 0.320 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.679 0.320 0.000
M54.44 Lumbago with sciatica-Thoracic
0.679 0.320 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.679 0.320 0.000
M54.42 Lumbago with sciatica-Cervical
0.679 0.320 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.679 0.320 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.679 0.320 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.679 0.320 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.679 0.320 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.679 0.320 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.679 0.320 0.000
R10.1 Pain localised to upper abdomen
0.679 0.321 0.000
R10.2 Pelvic and perineal pain
0.678 0.322 0.000
O43.8 Other placental disorders
0.677 0.323 0.000
O66 Other obstructed labour
0.677 0.323 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.677 0.323 0.000
M54.37 Sciatica (Lumbosacral region)
0.676 0.324 0.000
Z91.6 Personal history of other physical trauma
0.675 0.325 0.000
O21.0 Mild hyperemesis gravidarum
0.675 0.325 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.673 0.326 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.673 0.326 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.673 0.326 0.000
M51.9 Intervertebral disk disorder, unspecified
0.671 0.329 0.000
O42 Premature rupture of membranes
0.671 0.329 0.000
N18.4 Chronic kidney disease, stage 4
0.671 0.329 0.000
S59 Other and unspecified injuries of forearm
0.671 0.329 0.000
S58 Traumatic amputation of forearm
0.671 0.329 0.000
S57 Crushing injury of forearm
0.671 0.329 0.000
S55 Injury of blood vessels at forearm level
0.671 0.329 0.000
S54 Injury of nerves at forearm level
0.671 0.329 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.671 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.671 0.329 0.000
N17.9 Acute renal failure, unspecified
0.669 0.331 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
W50-W64 Exposure to animate mechanical forces
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.668 0.332 0.000
Q35-Q37 Cleft lip and cleft palate
0.668 0.332 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.668 0.332 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.668 0.332 0.000
M10 Gout
0.668 0.332 0.000
S02.0 Fracture of vault of skull
0.668 0.332 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.668 0.332 0.000
M54.35 Sciatica (Thoracolumbar region)
0.668 0.332 0.000
M54.34 Sciatica-Thoracic
0.668 0.332 0.000
M54.33 Sciatica-Cervicothoracic
0.668 0.332 0.000
M54.32 Sciatica-Cervical
0.668 0.332 0.000
M54.31 Sciatica-Occipit-atl-axl
0.668 0.332 0.000
M54.30 Sciatica (Multiple sites in spine)
0.668 0.332 0.000
O47 False labour
0.667 0.332 0.000
O74 Complications of anaesthesia during labour and delivery
0.667 0.333 0.000
O71 Other obstetric trauma
0.667 0.333 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.667 0.333 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.667 0.333 0.000
O61 Failed induction of labour
0.667 0.333 0.000
O60 Preterm delivery
0.667 0.333 0.000
T79-T79 Certain early complications of trauma
0.667 0.333 0.000
S90 Superficial injury of ankle and foot
0.667 0.333 0.000
M34 Systemic sclerosis
0.666 0.334 0.000
I69 Sequelae of cerebrovascular disease
0.666 0.334 0.000
S64 Injury of nerves at wrist and hand level
0.664 0.335 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.664 0.335 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.664 0.336 0.000
R11 Nausea and vomiting
0.664 0.336 0.000
S92 Fracture of foot, except ankle
0.663 0.336 0.000
N48.2 Other inflammatory disorders of penis
0.663 0.337 0.000
S50.9 Superficial injury of forearm, unspecified
0.663 0.337 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.662 0.338 0.000
M33 Dermatopolymyositis
0.662 0.338 0.000
M32 Systemic lupus erythematosus
0.662 0.338 0.000
M30 Polyarteritis nodosa and related conditions
0.662 0.338 0.000
C17 Malignant neoplasm of small intestine
0.662 0.338 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.662 0.338 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.661 0.339 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.661 0.339 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.661 0.339 0.000
S82.6 Fracture of lateral malleolus
0.661 0.339 0.000
V80-V89 Other land transport accidents
0.660 0.339 0.000
E10-E14 Diabetes mellitus
0.661 0.339 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.660 0.340 0.000
M35 Other systemic involvement of connective tissue
0.660 0.340 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.659 0.340 0.000
S69 Other and unspecified injuries of wrist and hand
0.659 0.340 0.000
S82.1 Fracture of upper end of tibia
0.659 0.341 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.659 0.341 0.000
N18.0 End-stage renal disease
0.659 0.341 0.000
H53-H54 Visual disturbances and blindness
0.659 0.341 0.000
Z90.1 Acquired absence of breast(s)
0.659 0.341 0.000
N81.5 Vaginal enterocele
0.659 0.341 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.658 0.342 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.658 0.342 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.657 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.657 0.343 0.000
Z92.9 Personal history of medical treatment, unspecified
0.656 0.344 0.000
Z92.5 Personal history of rehabilitation measures
0.656 0.344 0.000
O80-O84 Delivery
0.656 0.344 0.000
M40-M43 Deforming dorsopathies
0.655 0.345 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.655 0.345 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.655 0.345 0.000
S02.6 Fracture of mandible
0.654 0.346 0.000
M19.0 Primary arthrosis of other joints
0.654 0.346 0.000
S67 Crushing injury of wrist and hand
0.653 0.347 0.000
D46 Myelodysplastic syndromes
0.653 0.347 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.653 0.347 0.000
S02.10 Fracture of base of skull (closed)
0.653 0.347 0.000
M51.8 Other specified intervertebral disk disorders
0.652 0.348 0.000
C20 Malignant neoplasm of rectum
0.652 0.348 0.000
O29 Complications of anaesthesia during pregnancy
0.651 0.348 0.000
O28 Abnormal findings on antenatal screening of mother
0.651 0.348 0.000
O22 Venous complications in pregnancy
0.651 0.348 0.000
O25 Malnutrition in pregnancy
0.651 0.348 0.000
M54.29 Cervicalgia-Site unspe
0.651 0.349 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.651 0.349 0.000
M54.27 Cervicalgia-Lumbosacral
0.651 0.349 0.000
M54.26 Cervicalgia-Lumbar
0.651 0.349 0.000
M54.25 Cervicalgia-Thoracolumbar
0.651 0.349 0.000
M54.24 Cervicalgia-Thoracic
0.651 0.349 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.651 0.349 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.651 0.349 0.000
M54.20 Cervicalgia-Mult site
0.651 0.349 0.000
S80.7 Multiple superficial injuries of lower leg
0.650 0.349 0.000
S80.0 Contusion of knee
0.650 0.349 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.650 0.350 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.648 0.352 0.000
N87 Dysplasia of cervix uteri
0.648 0.352 0.000
Z49 Care involving dialysis
0.648 0.352 0.000
N84 Polyp of female genital tract
0.648 0.352 0.000
S99 Other and unspecified injuries of ankle and foot
0.647 0.353 0.000
M24 Other specific joint derangements
0.647 0.353 0.000
Z54 Convalescence
0.647 0.353 0.000
Z44 Fitting and adjustment of external prosthetic device
0.647 0.353 0.000
N90.6 Hypertrophy of vulva
0.647 0.353 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.647 0.353 0.000
W08 Fall involving other furniture
0.646 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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