TreeWAS – Variant ID: rs118048884

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000
K80 Cholelithiasis	1.000	0.000
M70-M79 Other soft tissue disorders	0.999	0.001
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.999	0.001
K55-K64 Other diseases of intestines	0.999	0.001
C15-C26 Malignant neoplasms of digestive organs	0.996	0.004
M75 Shoulder lesions	0.996	0.004
K62 Other diseases of anus and rectum	0.994	0.006
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.993	0.007
K62.8 Other specified diseases of anus and rectum	0.993	0.007
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.992	0.008
Chapter XV Pregnancy, childbirth and the puerperium	0.992	0.008
D37-D48 Neoplasms of uncertain or unknown behaviour	0.987	0.013
C15 Malignant neoplasm of oesophagus	0.984	0.016
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.983	0.017
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.982	0.018
Z90 Acquired absence of organs, not elsewhere classified	0.981	0.019
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.978	0.022
O60-O75 Complications of labour and delivery	0.978	0.022
Chapter VII Diseases of the eye and adnexa	0.976	0.024
Chapter IX Diseases of the circulatory system	0.972	0.028
M79 Other soft tissue disorders, not elsewhere classified	0.972	0.028
Z00-Z13 Persons encountering health services for examination and investigation	0.966	0.034
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.964	0.036
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.962	0.038
I83 Varicose veins of lower extremities	0.956	0.044
M75.4 Impingement syndrome of shoulder	0.953	0.047
C15.9 Oesophagus, unspecified	0.953	0.047
M05-M14 Inflammatory polyarthropathies	0.952	0.048
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.949	0.051
Z08 Follow-up examination after treatment for malignant neoplasm	0.946	0.054
Z90.1 Acquired absence of breast(s)	0.939	0.061
Z93 Artificial opening status	0.939	0.061
K80.2 Calculus of gallbladder without cholecystitis	0.934	0.066
T81 Complications of procedures, not elsewhere classified	0.932	0.068
M45-M49 Spondylopathies	0.931	0.069
K65-K67 Diseases of peritoneum	0.931	0.069
C78.0 Secondary malignant neoplasm of lung	0.930	0.070
Z83 Family history of other specific disorders	0.930	0.070
M75.0 Adhesive capsulitis of shoulder	0.921	0.079
K80.4 Calculus of bile duct with cholecystitis	0.921	0.079
T85 Complications of other internal prosthetic devices, implants and grafts	0.920	0.080
Z90.4 Acquired absence of other parts of digestive tract	0.920	0.080
D45 Polycythaemia vera	0.920	0.080
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.917	0.083
Z92 Personal history of medical treatment	0.917	0.083
K82 Other diseases of gallbladder	0.915	0.085
H30-H36 Disorders of choroid and retina	0.913	0.087
Z88.1 Personal history of allergy to other antibiotic agents	0.913	0.087
Z88.6 Personal history of allergy to analgesic agent	0.912	0.088
M06 Other rheumatoid arthritis	0.909	0.091
C15.5 Lower third of oesophagus	0.908	0.092
O63 Long labour	0.906	0.094
Chapter VIII Diseases of the ear and mastoid process	0.904	0.096
K83 Other diseases of biliary tract	0.902	0.098
Z97 Presence of other devices	0.899	0.101
H43-H45 Disorders of vitreous body and globe	0.898	0.102
M79.8 Other specified soft tissue disorders	0.896	0.104
M75.1 Rotator cuff syndrome	0.895	0.105
M79.6 Pain in limb	0.895	0.105
O73 Retained placenta and membranes, without haemorrhage	0.891	0.109
H35 Other retinal disorders	0.891	0.109
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.888	0.112
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.887	0.113
M50-M54 Other dorsopathies	0.884	0.116
H53-H54 Visual disturbances and blindness	0.884	0.116
M47 Spondylosis	0.883	0.117
K66 Other disorders of peritoneum	0.882	0.118
S60-S69 Injuries to the wrist and hand	0.881	0.119
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.880	0.120
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.875	0.125
K60 Fissure and fistula of anal and rectal regions	0.874	0.126
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.872	0.128
Chapter XII Diseases of the skin and subcutaneous tissue	0.872	0.128
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.865	0.134
Z92.2 Personal history of long-term (current) use of other medicaments	0.865	0.135
I05-I09 Chronic rheumatic heart diseases	0.864	0.136
Z88.4 Personal history of allergy to anaesthetic agent	0.861	0.139
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.861	0.139
K58 Irritable bowel syndrome	0.858	0.142
Z98 Other postsurgical states	0.854	0.146
H35.8 Other specified retinal disorders	0.850	0.150
Z93.2 Ileostomy status	0.848	0.152
Z83.5 Family history of eye and ear disorders	0.848	0.152
Z90.0 Acquired absence of part of head and neck	0.848	0.152
K66.0 Peritoneal adhesions	0.848	0.152
O63.1 Prolonged second stage (of labour)	0.848	0.152
Z09.8 Follow-up examination after other treatment for other conditions	0.845	0.155
C16 Malignant neoplasm of stomach	0.845	0.155
M06.9 Rheumatoid arthritis, unspecified	0.844	0.156
H65-H75 Diseases of middle ear and mastoid	0.841	0.159
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.840	0.159
C20 Malignant neoplasm of rectum	0.837	0.163
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.837	0.163
I84 Haemorrhoids	0.836	0.164
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.835	0.165
I30-I52 Other forms of heart disease	0.835	0.165
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.832	0.168
O73.0 Retained placenta, without haemorrhage	0.830	0.170
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.829	0.171
M75.5 Bursitis of shoulder	0.827	0.173
K70-K77 Diseases of liver	0.827	0.173
Z92.4 Personal history of major surgery, not elsewhere classified	0.823	0.177
K82.8 Other specified diseases of gallbladder	0.823	0.177
C64-C68 Malignant neoplasms of urinary tract	0.821	0.179
M79.86 Other specified soft tissue disorders (Lower leg)	0.820	0.180
D00-D09 In situ neoplasms	0.819	0.181
Z96 Presence of other functional implants	0.818	0.182
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.817	0.183
O80-O84 Delivery	0.816	0.184
M54 Dorsalgia	0.815	0.185
I70-I79 Diseases of arteries, arterioles and capillaries	0.815	0.185
O68 Labour and delivery complicated by foetal stress [distress]	0.813	0.187
K55 Vascular disorders of intestine	0.811	0.189
K61 Abscess of anal and rectal regions	0.811	0.189
M20-M25 Other joint disorders	0.809	0.191
M47.8 Other spondylosis	0.808	0.192
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.807	0.193
K62.7 Radiation proctitis	0.807	0.193
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.807	0.193
K83.0 Cholangitis	0.805	0.194
H43 Disorders of vitreous body	0.804	0.196
M80-M85 Disorders of bone density and structure	0.803	0.197
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.803	0.197
M86-M90 Other osteopathies	0.801	0.199
C51-C58 Malignant neoplasms of female genital organs	0.799	0.201
K56 Paralytic ileus and intestinal obstruction without hernia	0.799	0.201
M79.67 Pain in limb (Ankle and foot)	0.799	0.201
S90-S99 Injuries to the ankle and foot	0.798	0.202
K80.1 Calculus of gallbladder with other cholecystitis	0.797	0.203
I84.6 Residual haemorrhoidal skin tags	0.796	0.204
O36 Maternal care for other known or suspected foetal problems	0.794	0.206
K08 Other disorders of teeth and supporting structures	0.794	0.206
M40-M43 Deforming dorsopathies	0.792	0.208
M06.0 Seronegative rheumatoid arthritis	0.791	0.209
L20-L30 Dermatitis and eczema	0.791	0.209
Z88.5 Personal history of allergy to narcotic agent	0.790	0.210
H53 Visual disturbances	0.788	0.212
Z12 Special screening examination for neoplasms	0.787	0.213
K62.0 Anal polyp	0.785	0.215
Z87 Personal history of other diseases and conditions	0.784	0.216
D37.4 Colon	0.783	0.217
Z22 Carrier of infectious disease	0.781	0.219
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.780	0.219
O64 Obstructed labour due to malposition and malpresentation of foetus	0.777	0.223
Chapter I Certain infectious and parasitic diseases	0.776	0.224
C25 Malignant neoplasm of pancreas	0.776	0.224
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.775	0.225
T66-T78 Other and unspecified effects of external causes	0.773	0.227
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.773	0.227
Chapter XXII Codes for special purposes	0.773	0.227
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.771	0.229
O20-O29 Other maternal disorders predominantly related to pregnancy	0.771	0.229
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.770	0.230
M91-M94 Chondropathies	0.769	0.231
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.769	0.231
C19 Malignant neoplasm of rectosigmoid junction	0.768	0.231
K04 Diseases of pulp and periapical tissues	0.768	0.232
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.768	0.232
H72 Perforation of tympanic membrane	0.767	0.233
Z96.6 Presence of orthopaedic joint implants	0.764	0.236
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.762	0.238
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.761	0.239
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.760	0.240
K14 Diseases of tongue	0.760	0.240
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.760	0.240
Z35 Supervision of high-risk pregnancy	0.759	0.241
T86 Failure and rejection of transplanted organs and tissues	0.757	0.243
K80.8 Other cholelithiasis	0.757	0.243
K60.3 Anal fistula	0.756	0.244
C78.2 Secondary malignant neoplasm of pleura	0.755	0.245
M47.86 Other spondylosis (Lumbar region)	0.753	0.247
K62.9 Disease of anus and rectum, unspecified	0.753	0.247
Z97.4 Presence of external hearing-aid	0.751	0.249
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.750	0.250
H35.0 Background retinopathy and retinal vascular changes	0.749	0.251
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.749	0.251
Z93.0 Tracheostomy status	0.748	0.252
Z88.2 Personal history of allergy to sulphonamides	0.748	0.252
M77 Other enthesopathies	0.747	0.253
H44 Disorders of globe	0.747	0.253
S20-S29 Injuries to the thorax	0.747	0.253
O94-O99 Other obstetric conditions, not elsewhere classified	0.745	0.255
D46 Myelodysplastic syndromes	0.744	0.256
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.744	0.256
D10-D36 Benign neoplasms	0.743	0.257
M47.2 Other spondylosis with radiculopathy	0.743	0.257
I34 Nonrheumatic mitral valve disorders	0.742	0.258
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.740	0.260
Z97.5 Presence of (intra-uterine) contraceptive device	0.739	0.261
O82 Single delivery by Caesarean section	0.739	0.261
M05 Seropositive rheumatoid arthritis	0.737	0.263
C16.0 Cardia	0.736	0.264
O47 False labour	0.736	0.264
I08 Multiple valve diseases	0.736	0.264
M25 Other joint disorders, not elsewhere classified	0.736	0.264
O72 Postpartum haemorrhage	0.735	0.265
S80-S89 Injuries to the knee and lower leg	0.735	0.265
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.733	0.267
Z93.6 Other artificial openings of urinary tract status	0.733	0.267
Z98.1 Arthrodesis status	0.733	0.267
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.731	0.269
H43.8 Other disorders of vitreous body	0.731	0.269
O75 Other complications of labour and delivery, not elsewhere classified	0.730	0.270
M79.66 Pain in limb (Lower leg)	0.730	0.270
K80.0 Calculus of gallbladder with acute cholecystitis	0.727	0.273
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.726	0.274
Chapter XX External causes of morbidity and mortality	0.725	0.275
C79 Secondary malignant neoplasm of other sites	0.725	0.275
K07 Dentofacial anomalies [including malocclusion]	0.725	0.275
Z37 Outcome of delivery	0.725	0.275
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.725	0.275
Z83.3 Family history of diabetes mellitus	0.724	0.275
B95-B98 Bacterial, viral and other infectious agents	0.723	0.277
Z83.7 Family history of diseases of the digestive system	0.723	0.277
H35.6 Retinal haemorrhage	0.723	0.277
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.723	0.277
Z93.3 Colostomy status	0.723	0.277
K06 Other disorders of gingiva and edentulous alveolar ridge	0.722	0.278
T85.2 Mechanical complication of intraocular lens	0.722	0.278
M10 Gout	0.721	0.279
S61 Open wound of wrist and hand	0.720	0.280
I83.0 Varicose veins of lower extremities with ulcer	0.720	0.280
O69 Labour and delivery complicated by umbilical cord complications	0.719	0.281
Z90.6 Acquired absence of other parts of urinary tract	0.719	0.281
M54.9 Dorsalgia, unspecified	0.719	0.281
I87 Other disorders of veins	0.718	0.282
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283
K80.3 Calculus of bile duct with cholangitis	0.717	0.283
M76 Enthesopathies of lower limb, excluding foot	0.716	0.283
M73 Soft tissue disorders in diseases classified elsewhere	0.716	0.283
M71 Other bursopathies	0.716	0.283
M70 Soft tissue disorders related to use, overuse and pressure	0.716	0.283
Z89 Acquired absence of limb	0.716	0.284
Z84 Family history of other conditions	0.716	0.284
Z81 Family history of mental and behavioural disorders	0.716	0.284
H90-H95 Other disorders of ear	0.716	0.284
K64 Haemorrhoids and perianal venous thrombosis	0.716	0.284
D37.7 Other digestive organs	0.716	0.284
M79.7 Fibromyalgia	0.716	0.284
Z22.3 Carrier of other specified bacterial diseases	0.716	0.284
O32 Maternal care for known or suspected malpresentation of foetus	0.715	0.285
K82.1 Hydrops of gallbladder	0.715	0.285
M11 Other crystal arthropathies	0.715	0.285
C26 Malignant neoplasm of other and ill-defined digestive organs	0.714	0.286
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.714	0.286
C21 Malignant neoplasm of anus and anal canal	0.714	0.286
C17 Malignant neoplasm of small intestine	0.714	0.286
C23 Malignant neoplasm of gallbladder	0.714	0.286
H55-H59 Other disorders of eye and adnexa	0.714	0.286
M75.8 Other shoulder lesions	0.714	0.286
M75.9 Shoulder lesion, unspecified	0.714	0.286
M75.3 Calcific tendinitis of shoulder	0.714	0.286
M75.2 Bicipital tendinitis	0.714	0.286
K08.3 Retained dental root	0.714	0.286
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.713	0.287
K62.4 Stenosis of anus and rectum	0.713	0.287
K62.2 Anal prolapse	0.713	0.287
I47 Paroxysmal tachycardia	0.713	0.287
C73 Malignant neoplasm of thyroid gland	0.712	0.288
T33-T35 Frostbite	0.712	0.288
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.712	0.288
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.288
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.288
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.712	0.288
T00-T07 Injuries involving multiple body regions	0.712	0.288
S10-S19 Injuries to the neck	0.712	0.288
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.711	0.288
O85-O92 Complications predominantly related to the puerperium	0.711	0.289
H54 Blindness and low vision	0.710	0.290
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.710	0.290
Z90.3 Acquired absence of part of stomach	0.710	0.290
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.710	0.290
M07 Psoriatic and enteropathic arthropathies	0.709	0.291
K10 Other diseases of jaws	0.709	0.291
K05 Gingivitis and periodontal diseases	0.708	0.291
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.708	0.292
K58.9 Irritable bowel syndrome without diarrhoea	0.708	0.292
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.708	0.292
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.708	0.292
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.708	0.292
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.708	0.292
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.708	0.292
H10-H13 Disorders of conjunctiva	0.706	0.294
T79-T79 Certain early complications of trauma	0.706	0.294
T15-T19 Effects of foreign body entering through natural orifice	0.706	0.294
C15.8 Overlapping lesion of oesophagus	0.706	0.294
C15.4 Middle third of oesophagus	0.706	0.294
C15.3 Upper third of oesophagus	0.706	0.294
C15.2 Abdominal part of oesophagus	0.706	0.294
C15.1 Thoracic part of oesophagus	0.706	0.294
C15.0 Cervical part of oesophagus	0.706	0.294
S62 Fracture at wrist and hand level	0.705	0.295
I85 Oesophageal varices	0.705	0.295
Z34 Supervision of normal pregnancy	0.705	0.295
C76 Malignant neoplasm of other and ill-defined sites	0.704	0.295
Z90.5 Acquired absence of kidney	0.704	0.295
K50-K52 Noninfective enteritis and colitis	0.704	0.296
T87 Complications peculiar to reattachment and amputation	0.704	0.296
T80 Complications following infusion, transfusion and therapeutic injection	0.704	0.296
K60.0 Acute anal fissure	0.703	0.296
Z90.8 Acquired absence of other organs	0.703	0.297
C43-C44 Melanoma and other malignant neoplasms of skin	0.703	0.297
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.701	0.299
Z88.7 Personal history of allergy to serum and vaccine	0.701	0.299
Z97.8 Presence of other specified devices	0.701	0.299
O74 Complications of anaesthesia during labour and delivery	0.701	0.299
O71 Other obstetric trauma	0.701	0.299
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.701	0.299
O66 Other obstructed labour	0.701	0.299
O65 Obstructed labour due to maternal pelvic abnormality	0.701	0.299
O62 Abnormalities of forces of labour	0.701	0.299
O61 Failed induction of labour	0.701	0.299
O60 Preterm delivery	0.701	0.299
K83.8 Other specified diseases of biliary tract	0.700	0.300
H46-H48 Disorders of optic nerve and visual pathways	0.700	0.300
Z93.5 Cystostomy status	0.699	0.301
K62.6 Ulcer of anus and rectum	0.699	0.301
M79.0 Rheumatism, unspecified	0.698	0.302
I00-I02 Acute rheumatic fever	0.697	0.303
M79.9 Soft tissue disorder, unspecified	0.697	0.303
M79.5 Residual foreign body in soft tissue	0.697	0.303
M79.4 Hypertrophy of (infrapatellar) fat pad	0.697	0.303
M79.3 Panniculitis, unspecified	0.697	0.303
M79.2 Neuralgia and neuritis, unspecified	0.697	0.303
M79.1 Myalgia	0.697	0.303
C77.1 Intrathoracic lymph nodes	0.696	0.304
T84.1 Mechanical complication of internal fixation device of bones of limb	0.696	0.304
S40-S49 Injuries to the shoulder and upper arm	0.696	0.304
K58.0 Irritable bowel syndrome with diarrhoea	0.695	0.305
C54 Malignant neoplasm of corpus uteri	0.695	0.305
M79.89 Other specified soft tissue disorders (Site unspecified)	0.694	0.305
Z10 Routine general health check-up of defined subpopulation	0.693	0.307
M79.64 Pain in limb (Hand)	0.692	0.307
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.692	0.308
I88 Nonspecific lymphadenitis	0.691	0.309
I86 Varicose veins of other sites	0.691	0.309
I82 Other venous embolism and thrombosis	0.691	0.309
I81 Portal vein thrombosis	0.691	0.309
K82.4 Cholesterolosis of gallbladder	0.691	0.309
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.690	0.310
C78.4 Secondary malignant neoplasm of small intestine	0.690	0.310
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.690	0.310
C78.1 Secondary malignant neoplasm of mediastinum	0.690	0.310
T81.4 Infection following a procedure, not elsewhere classified	0.690	0.310
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.689	0.311
S50-S59 Injuries to the elbow and forearm	0.688	0.312
I83.1 Varicose veins of lower extremities with inflammation	0.688	0.312
K76 Other diseases of liver	0.688	0.312
Z11 Special screening examination for infectious and parasitic diseases	0.687	0.313
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.687	0.313
T85.4 Mechanical complication of breast prosthesis and implant	0.686	0.314
I77 Other disorders of arteries and arterioles	0.685	0.315
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.685	0.315
L40-L45 Papulosquamous disorders	0.685	0.315
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.685	0.315
M79.65 Pain in limb (Pelvic region and thigh)	0.684	0.316
C50-C50 Malignant neoplasm of breast	0.684	0.316
K56.7 Ileus, unspecified	0.684	0.316
I07 Rheumatic tricuspid valve diseases	0.684	0.316
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.684	0.316
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.683	0.317
T88 Other complications of surgical and medical care, not elsewhere classified	0.682	0.317
M14 Arthropathies in other diseases classified elsewhere	0.682	0.318
M12 Other specific arthropathies	0.682	0.318
M09 Juvenile arthritis in diseases classified elsewhere	0.682	0.318
M08 Juvenile arthritis	0.682	0.318
M47.87 Other spondylosis (Lumbosacral region)	0.681	0.319
L30 Other dermatitis	0.681	0.319
M47.9 Spondylosis, unspecified	0.680	0.320
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.680	0.320
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.680	0.320
D05 Carcinoma in situ of breast	0.678	0.322
T81.3 Disruption of operation wound, not elsewhere classified	0.677	0.323
D12.8 Rectum	0.677	0.323
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.676	0.324
S70-S79 Injuries to the hip and thigh	0.675	0.325
K85 Acute pancreatitis	0.674	0.326
M81 Osteoporosis without pathological fracture	0.674	0.326
O63.9 Long labour, unspecified	0.674	0.326
K61.0 Anal abscess	0.674	0.326
Z93.9 Artificial opening status, unspecified	0.673	0.326
Z93.8 Other artificial opening status	0.673	0.326
Z93.4 Other artificial openings of gastro-intestinal tract status	0.673	0.326
Z98.8 Other specified postsurgical states	0.672	0.328
I49 Other cardiac arrhythmias	0.671	0.329
D40.1 Testis	0.671	0.329
K12 Stomatitis and related lesions	0.670	0.330
I72 Other aneurysm	0.670	0.330
L00-L08 Infections of the skin and subcutaneous tissue	0.670	0.330
K62.1 Rectal polyp	0.670	0.330
L29 Pruritus	0.670	0.330
K83.1 Obstruction of bile duct	0.669	0.331
K55.2 Angiodysplasia of colon	0.669	0.331
M25.5 Pain in joint	0.669	0.331
T81.9 Unspecified complication of procedure	0.668	0.332
T81.7 Vascular complications following a procedure, not elsewhere classified	0.668	0.332
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.668	0.332
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.668	0.332
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.668	0.332
C77.3 Axillary and upper limb lymph nodes	0.668	0.332
I84.4 External haemorrhoids with other complications	0.668	0.332
M49 Spondylopathies in diseases classified elsewhere	0.668	0.332
M46 Other inflammatory spondylopathies	0.668	0.332
M45 Ankylosing spondylitis	0.668	0.332
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.667	0.333
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.667	0.333
H40-H42 Glaucoma	0.667	0.333
Z83.6 Family history of diseases of the respiratory system	0.666	0.333
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.666	0.333
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.666	0.333
Z83.1 Family history of other infectious and parasitic diseases	0.666	0.333
Z83.0 Family history of human immunodeficiency virus [HIV]	0.666	0.333
I08.1 Disorders of both mitral and tricuspid valves	0.666	0.334
O82.0 Delivery by elective Caesarean section	0.665	0.335
H53.8 Other visual disturbances	0.665	0.335
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.664	0.336
T93 Sequelae of injuries of lower limb	0.664	0.336
C78.7 Secondary malignant neoplasm of liver	0.664	0.336
I05 Rheumatic mitral valve diseases	0.663	0.337
M54.5 Low back pain	0.662	0.338
K14.8 Other diseases of tongue	0.661	0.338
K65 Peritonitis	0.661	0.339
I47.2 Ventricular tachycardia	0.661	0.339
M48 Other spondylopathies	0.660	0.340
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.660	0.340
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.660	0.340
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.660	0.340
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.660	0.340
T84.0 Mechanical complication of internal joint prosthesis	0.659	0.341
K60.1 Chronic anal fissure	0.659	0.341
I35 Nonrheumatic aortic valve disorders	0.659	0.341
Z35.5 Supervision of elderly primigravida	0.659	0.341
H43.3 Other vitreous opacities	0.659	0.341
H74 Other disorders of middle ear and mastoid	0.658	0.341
Z12.1 Special screening examination for neoplasm of intestinal tract	0.658	0.342
O30 Multiple gestation	0.658	0.342
K35-K38 Diseases of appendix	0.658	0.342
K09 Cysts of oral region, not elsewhere classified	0.658	0.342
K03 Other diseases of hard tissues of teeth	0.658	0.342
K00 Disorders of tooth development and eruption	0.658	0.342
Z92.9 Personal history of medical treatment, unspecified	0.658	0.342
Z92.8 Personal history of other medical treatment	0.658	0.342
Z92.5 Personal history of rehabilitation measures	0.658	0.342
Z92.0 Personal history of contraception	0.658	0.342
S69 Other and unspecified injuries of wrist and hand	0.656	0.344
M79.84 Other specified soft tissue disorders (Hand)	0.656	0.344
C67 Malignant neoplasm of bladder	0.656	0.344
O63.0 Prolonged first stage (of labour)	0.656	0.344
K82.9 Disease of gallbladder, unspecified	0.656	0.344
K82.3 Fistula of gallbladder	0.656	0.344
K82.2 Perforation of gallbladder	0.656	0.344
K82.0 Obstruction of gallbladder	0.656	0.344
O36.0 Maternal care for rhesus isoimmunisation	0.656	0.344
T91 Sequelae of injuries of neck and trunk	0.655	0.345
S61.0 Open wound of finger(s) without damage to nail	0.655	0.345
H32 Chorioretinal disorders in diseases classified elsewhere	0.655	0.345
H31 Other disorders of choroid	0.655	0.345
H30 Chorioretinal inflammation	0.655	0.345
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.654	0.346
O46 Antepartum haemorrhage, not elsewhere classified	0.654	0.346
M89 Other disorders of bone	0.652	0.348
M06.8 Other specified rheumatoid arthritis	0.652	0.348
M06.4 Inflammatory polyarthropathy	0.652	0.348
M06.3 Rheumatoid nodule	0.652	0.348
M06.2 Rheumatoid bursitis	0.652	0.348
M06.1 Adult-onset Still's disease	0.652	0.348
D36 Benign neoplasm of other and unspecified sites	0.651	0.349
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.651	0.349
K70 Alcoholic liver disease	0.650	0.349
Z39 Postpartum care and examination	0.650	0.350
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.650	0.350
K86 Other diseases of pancreas	0.650	0.350
O63.2 Delayed delivery of second twin, triplet, etc.	0.650	0.350
Z01.6 Radiological examination, not elsewhere classified	0.649	0.351
M79.60 Pain in limb (Multiple sites)	0.649	0.351
K51 Ulcerative colitis	0.648	0.352
K57 Diverticular disease of intestine	0.648	0.352
I84.1 Internal haemorrhoids with other complications	0.648	0.352
Z40-Z54 Persons encountering health services for specific procedures and health care	0.647	0.353
K83.9 Disease of biliary tract, unspecified	0.647	0.353
K83.5 Biliary cyst	0.647	0.353
K83.4 Spasm of sphincter of Oddi	0.647	0.353
K83.3 Fistula of bile duct	0.647	0.353
K83.2 Perforation of bile duct	0.647	0.353
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.646	0.354
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.646	0.354
Z97.3 Presence of spectacles and contact lenses	0.644	0.356
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.644	0.356

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations