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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118083488
log Bayes Factor = 17.572
Chromosome 6   position 159,789,012  (GRCh37) Explore rs118083488 on Ensembl!
Variant rs118083488 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
R07 Pain in throat and chest
0.998 0.002 0.000
Z80 Family history of malignant neoplasm
0.994 0.006 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.992 0.008 0.000
R01 Cardiac murmurs and other cardiac sounds
0.991 0.009 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
Z86 Personal history of certain other diseases
0.985 0.015 0.000
R01.1 Cardiac murmur, unspecified
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
Chapter XI Diseases of the digestive system
0.978 0.022 0.000
K50-K52 Noninfective enteritis and colitis
0.978 0.022 0.000
Z86.4 Personal history of psychoactive substance abuse
0.976 0.024 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.975 0.025 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.973 0.027 0.000
R07.3 Other chest pain
0.973 0.027 0.000
R07.2 Precordial pain
0.972 0.028 0.000
Z03.4 Observation for suspected myocardial infarction
0.967 0.033 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.967 0.033 0.000
F10.1 Harmful use
0.966 0.034 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.964 0.036 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.961 0.039 0.000
K50 Crohn's disease [regional enteritis]
0.957 0.043 0.000
K51 Ulcerative colitis
0.955 0.045 0.000
R07.4 Chest pain, unspecified
0.955 0.045 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.949 0.051 0.000
I25 Chronic ischaemic heart disease
0.947 0.053 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.946 0.054 0.000
F10.0 Acute intoxication
0.944 0.056 0.000
S00-S09 Injuries to the head
0.942 0.058 0.000
Z72 Problems related to lifestyle
0.939 0.061 0.000
I20 Angina pectoris
0.939 0.061 0.000
G40-G47 Episodic and paroxysmal disorders
0.938 0.062 0.000
K70-K77 Diseases of liver
0.938 0.062 0.000
Z80.3 Family history of malignant neoplasm of breast
0.937 0.063 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.935 0.065 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.934 0.066 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.931 0.069 0.000
I22 Subsequent myocardial infarction
0.930 0.070 0.000
S60-S69 Injuries to the wrist and hand
0.928 0.072 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.928 0.072 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.924 0.076 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.918 0.082 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.916 0.084 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.913 0.087 0.000
I35 Nonrheumatic aortic valve disorders
0.909 0.091 0.000
I51 Complications and ill-defined descriptions of heart disease
0.908 0.092 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.904 0.096 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.899 0.101 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.898 0.102 0.000
K70 Alcoholic liver disease
0.894 0.106 0.000
I21 Acute myocardial infarction
0.891 0.109 0.000
Z86.0 Personal history of other neoplasms
0.889 0.111 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.886 0.114 0.000
S80-S89 Injuries to the knee and lower leg
0.883 0.117 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.882 0.118 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.880 0.120 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.878 0.122 0.000
Z90.1 Acquired absence of breast(s)
0.876 0.124 0.000
Z72.0 Tobacco use
0.875 0.125 0.000
G40 Epilepsy
0.872 0.128 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.869 0.131 0.000
K51.9 Ulcerative colitis, unspecified
0.869 0.131 0.000
E70-E90 Metabolic disorders
0.866 0.134 0.000
I25.2 Old myocardial infarction
0.865 0.135 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.865 0.135 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.861 0.139 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.860 0.140 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.857 0.143 0.000
Z72.1 Alcohol use
0.857 0.143 0.000
K50.1 Crohn's disease of large intestine
0.852 0.148 0.000
K52 Other non-infective gastro-enteritis and colitis
0.852 0.148 0.000
I20.8 Other forms of angina pectoris
0.849 0.151 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.848 0.151 0.000
I46 Cardiac arrest
0.848 0.152 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.846 0.154 0.000
I25.1 Atherosclerotic heart disease
0.844 0.156 0.000
K50.0 Crohn's disease of small intestine
0.843 0.157 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.840 0.160 0.000
Z90.2 Acquired absence of lung [part of]
0.835 0.165 0.000
T90 Sequelae of injuries of head
0.835 0.165 0.000
I44 Atrioventricular and left bundle-branch block
0.835 0.165 0.000
K51.2 Ulcerative (chronic) proctitis
0.835 0.165 0.000
R01.0 Benign and innocent cardiac murmurs
0.831 0.169 0.000
G90-G99 Other disorders of the nervous system
0.827 0.173 0.000
I35.1 Aortic (valve) insufficiency
0.827 0.173 0.000
K50.9 Crohn's disease, unspecified
0.826 0.174 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.825 0.175 0.000
Z97 Presence of other devices
0.824 0.176 0.000
Z99.3 Dependence on wheelchair
0.824 0.176 0.000
K74 Fibrosis and cirrhosis of liver
0.822 0.178 0.000
F10.3 Withdrawal state
0.820 0.180 0.000
S09 Other and unspecified injuries of head
0.819 0.181 0.000
I51.9 Heart disease, unspecified
0.818 0.182 0.000
S40-S49 Injuries to the shoulder and upper arm
0.818 0.182 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.816 0.184 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.813 0.187 0.000
K55-K64 Other diseases of intestines
0.813 0.187 0.000
K65-K67 Diseases of peritoneum
0.810 0.190 0.000
I10-I15 Hypertensive diseases
0.808 0.192 0.000
S00 Superficial injury of head
0.806 0.194 0.000
K70.9 Alcoholic liver disease, unspecified
0.805 0.195 0.000
I20.0 Unstable angina
0.805 0.195 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.805 0.195 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.805 0.195 0.000
I24 Other acute ischaemic heart diseases
0.803 0.197 0.000
S62 Fracture at wrist and hand level
0.799 0.201 0.000
F03 Unspecified dementia
0.799 0.201 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.798 0.202 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.798 0.202 0.000
Q60-Q64 Congenital malformations of the urinary system
0.798 0.202 0.000
I49 Other cardiac arrhythmias
0.797 0.203 0.000
S65 Injury of blood vessels at wrist and hand level
0.797 0.203 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.794 0.206 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.793 0.207 0.000
I21.9 Acute myocardial infarction, unspecified
0.793 0.207 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.791 0.209 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.789 0.211 0.000
Z99.2 Dependence on renal dialysis
0.789 0.211 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.788 0.212 0.000
T86 Failure and rejection of transplanted organs and tissues
0.787 0.213 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.786 0.214 0.000
E20-E35 Disorders of other endocrine glands
0.786 0.214 0.000
F99-F99 Unspecified mental disorder
0.786 0.214 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.785 0.215 0.000
R41.0 Disorientation, unspecified
0.785 0.215 0.000
Z04 Examination and observation for other reasons
0.785 0.215 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.785 0.215 0.000
G40.9 Epilepsy, unspecified
0.782 0.218 0.000
R45 Symptoms and signs involving emotional state
0.778 0.222 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.778 0.222 0.000
R50-R69 General symptoms and signs
0.777 0.223 0.000
R41.2 Retrograde amnesia
0.777 0.223 0.000
E87.6 Hypokalaemia
0.776 0.224 0.000
F10.2 Dependence syndrome
0.776 0.224 0.000
G56 Mononeuropathies of upper limb
0.776 0.224 0.000
S02 Fracture of skull and facial bones
0.775 0.225 0.000
I31 Other diseases of pericardium
0.775 0.225 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.771 0.229 0.000
Z94 Transplanted organ and tissue status
0.771 0.229 0.000
Chapter XXII Codes for special purposes
0.770 0.230 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.769 0.231 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.768 0.232 0.000
R07.1 Chest pain on breathing
0.765 0.235 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.764 0.236 0.000
F30-F39 Mood [affective] disorders
0.764 0.236 0.000
K50.8 Other Crohn's disease
0.764 0.236 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.763 0.237 0.000
Z98 Other postsurgical states
0.762 0.238 0.000
Chapter II Neoplasms
0.760 0.240 0.000
G30-G32 Other degenerative diseases of the nervous system
0.759 0.241 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.759 0.241 0.000
S64 Injury of nerves at wrist and hand level
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.758 0.242 0.000
F60-F69 Disorders of adult personality and behaviour
0.758 0.242 0.000
I45 Other conduction disorders
0.757 0.243 0.000
I51.6 Cardiovascular disease, unspecified
0.756 0.244 0.000
T93 Sequelae of injuries of lower limb
0.755 0.245 0.000
K51.5 Mucosal proctocolitis
0.753 0.247 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.753 0.247 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.753 0.247 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.753 0.247 0.000
Z95.2 Presence of prosthetic heart valve
0.751 0.249 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.751 0.249 0.000
K70.3 Alcoholic cirrhosis of liver
0.750 0.250 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.750 0.250 0.000
Z90.8 Acquired absence of other organs
0.750 0.250 0.000
Y84.0 Cardiac catheterisation
0.749 0.250 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.749 0.251 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.749 0.251 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.747 0.253 0.000
I05-I09 Chronic rheumatic heart diseases
0.747 0.253 0.000
Z89 Acquired absence of limb
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.746 0.254 0.000
Z95.3 Presence of xenogenic heart valve
0.745 0.254 0.000
G57 Mononeuropathies of lower limb
0.745 0.255 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.744 0.256 0.000
S70-S79 Injuries to the hip and thigh
0.743 0.257 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.743 0.257 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
T91 Sequelae of injuries of neck and trunk
0.741 0.259 0.000
Z73 Problems related to life-management difficulty
0.739 0.261 0.000
S81 Open wound of lower leg
0.739 0.261 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.738 0.262 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.736 0.264 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.736 0.264 0.000
G41 Status epilepticus
0.735 0.265 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.734 0.265 0.000
I20.9 Angina pectoris, unspecified
0.734 0.266 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.734 0.266 0.000
K51.8 Other ulcerative colitis
0.733 0.267 0.000
L40-L45 Papulosquamous disorders
0.732 0.268 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.732 0.268 0.000
E65-E68 Obesity and other hyperalimentation
0.732 0.268 0.000
S09.9 Unspecified injury of head
0.731 0.269 0.000
G70-G73 Diseases of myoneural junction and muscle
0.730 0.269 0.000
Y84.8 Other medical procedures
0.730 0.270 0.000
G43 Migraine
0.728 0.272 0.000
R41.3 Other amnesia
0.728 0.272 0.000
I46.0 Cardiac arrest with successful resuscitation
0.728 0.272 0.000
K72 Hepatic failure, not elsewhere classified
0.727 0.273 0.000
Z99.8 Dependence on other enabling machines and devices
0.725 0.275 0.000
L91 Hypertrophic disorders of skin
0.724 0.276 0.000
W00-W19 Falls
0.724 0.276 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.722 0.278 0.000
S50-S59 Injuries to the elbow and forearm
0.722 0.278 0.000
R69 Unknown and unspecified causes of morbidity
0.722 0.278 0.000
T82.1 Mechanical complication of cardiac electronic device
0.721 0.279 0.000
K51.4 Pseudopolyposis of colon
0.721 0.279 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.720 0.280 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.720 0.280 0.000
I34 Nonrheumatic mitral valve disorders
0.719 0.281 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.719 0.281 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.719 0.281 0.000
S80 Superficial injury of lower leg
0.718 0.282 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
E50-E64 Other nutritional deficiencies
0.716 0.284 0.000
K74.6 Other and unspecified cirrhosis of liver
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.284 0.000
F80-F89 Disorders of psychological development
0.715 0.284 0.000
F70-F79 Mental retardation
0.715 0.284 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.712 0.287 0.000
Z80.6 Family history of leukaemia
0.712 0.287 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.712 0.287 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.711 0.289 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.289 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.711 0.289 0.000
F11 Mental and behavioural disorders due to use of opioids
0.711 0.289 0.000
R01.2 Other cardiac sounds
0.711 0.289 0.000
Chapter VII Diseases of the eye and adnexa
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
I44.7 Left bundle-branch block, unspecified
0.710 0.290 0.000
F10.9 Unspecified mental and behavioural disorder
0.709 0.290 0.000
F10.8 Other mental and behavioural disorders
0.709 0.290 0.000
F10.7 Residual and late-onset psychotic disorder
0.709 0.290 0.000
F10.6 Amnesic syndrome
0.709 0.290 0.000
F10.5 Psychotic disorder
0.709 0.290 0.000
F10.4 Withdrawal state with delirium
0.709 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.707 0.293 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.707 0.293 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.707 0.293 0.000
Z75 Problems related to medical facilities and other health care
0.706 0.294 0.000
K63 Other diseases of intestine
0.706 0.294 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.705 0.295 0.000
I33 Acute and subacute endocarditis
0.705 0.295 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.704 0.296 0.000
S65.5 Injury of blood vessel(s) of other finger
0.704 0.296 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
I44.2 Atrioventricular block, complete
0.703 0.297 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.702 0.298 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
T90.5 Sequelae of intracranial injury
0.702 0.298 0.000
Q80-Q89 Other congenital malformations
0.701 0.299 0.000
K70.0 Alcoholic fatty liver
0.701 0.299 0.000
S20-S29 Injuries to the thorax
0.701 0.299 0.000
S06 Intracranial injury
0.701 0.299 0.000
G95 Other diseases of spinal cord
0.700 0.300 0.000
Z90.0 Acquired absence of part of head and neck
0.700 0.300 0.000
D00-D09 In situ neoplasms
0.699 0.301 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.698 0.301 0.000
Z10 Routine general health check-up of defined subpopulation
0.698 0.302 0.000
I24.8 Other forms of acute ischaemic heart disease
0.697 0.303 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.697 0.303 0.000
R63 Symptoms and signs concerning food and fluid intake
0.695 0.305 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
Z76 Persons encountering health services in other circumstances
0.693 0.307 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.693 0.307 0.000
Z90.3 Acquired absence of part of stomach
0.693 0.307 0.000
F01 Vascular dementia
0.693 0.307 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.692 0.308 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.691 0.308 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.691 0.308 0.000
Z03.0 Observation for suspected tuberculosis
0.691 0.308 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.691 0.309 0.000
C15-C26 Malignant neoplasms of digestive organs
0.689 0.311 0.000
E73 Lactose intolerance
0.689 0.311 0.000
E83 Disorders of mineral metabolism
0.689 0.311 0.000
R46 Symptoms and signs involving appearance and behaviour
0.689 0.311 0.000
R43 Disturbances of smell and taste
0.689 0.311 0.000
T66-T78 Other and unspecified effects of external causes
0.687 0.312 0.000
C50-C50 Malignant neoplasm of breast
0.687 0.313 0.000
Z82.3 Family history of stroke
0.686 0.314 0.000
Y52 Agents primarily affecting the cardiovascular system
0.686 0.314 0.000
K58 Irritable bowel syndrome
0.686 0.314 0.000
K70.1 Alcoholic hepatitis
0.685 0.315 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.685 0.315 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.685 0.315 0.000
R40 Somnolence, stupor and coma
0.684 0.316 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.683 0.317 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
G58 Other mononeuropathies
0.682 0.318 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.682 0.318 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.681 0.318 0.000
Y83.8 Other surgical procedures
0.681 0.319 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.679 0.321 0.000
I35.8 Other aortic valve disorders
0.679 0.321 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
I25.6 Silent myocardial ischaemia
0.679 0.321 0.000
I25.4 Coronary artery aneurysm
0.679 0.321 0.000
I25.3 Aneurysm of heart
0.679 0.321 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.679 0.321 0.000
I51.8 Other ill-defined heart diseases
0.679 0.321 0.000
T51 Toxic effect of alcohol
0.679 0.321 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.678 0.322 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.678 0.322 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.678 0.322 0.000
T82.3 Mechanical complication of other vascular grafts
0.678 0.322 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.678 0.322 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.678 0.322 0.000
S67 Crushing injury of wrist and hand
0.677 0.323 0.000
T92 Sequelae of injuries of upper limb
0.676 0.324 0.000
S08 Traumatic amputation of part of head
0.676 0.324 0.000
S07 Crushing injury of head
0.676 0.324 0.000
S05 Injury of eye and orbit
0.676 0.324 0.000
S04 Injury of cranial nerves
0.676 0.324 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.676 0.324 0.000
Q61 Cystic kidney disease
0.675 0.325 0.000
I35.9 Aortic valve disorder, unspecified
0.674 0.325 0.000
I42 Cardiomyopathy
0.674 0.326 0.000
Z72.9 Problem related to lifestyle, unspecified
0.673 0.327 0.000
Z72.8 Other problems related to lifestyle
0.673 0.327 0.000
Z72.6 Gambling and betting
0.673 0.327 0.000
Z72.5 High-risk sexual behaviour
0.673 0.327 0.000
Z72.4 Inappropriate diet and eating habits
0.673 0.327 0.000
Z72.3 Lack of physical exercise
0.673 0.327 0.000
Z72.2 Drug use
0.673 0.327 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.673 0.327 0.000
I86 Varicose veins of other sites
0.673 0.327 0.000
K65 Peritonitis
0.672 0.327 0.000
K77 Liver disorders in diseases classified elsewhere
0.672 0.328 0.000
K73 Chronic hepatitis, not elsewhere classified
0.672 0.328 0.000
K71 Toxic liver disease
0.672 0.328 0.000
I47 Paroxysmal tachycardia
0.672 0.328 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.672 0.328 0.000
L89 Decubitus ulcer
0.671 0.329 0.000
K63.5 Polyp of colon
0.671 0.329 0.000
I21.4 Acute subendocardial myocardial infarction
0.670 0.329 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.670 0.330 0.000
K61 Abscess of anal and rectal regions
0.670 0.330 0.000
T98 Sequelae of other and unspecified effects of external causes
0.669 0.330 0.000
T95 Sequelae of burns, corrosions and frostbite
0.669 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.669 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.669 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.669 0.330 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.669 0.330 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
Y84.6 Urinary catheterisation
0.669 0.331 0.000
R53 Malaise and fatigue
0.668 0.332 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.667 0.333 0.000
I22.8 Subsequent myocardial infarction of other sites
0.666 0.333 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.666 0.333 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.667 0.333 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.666 0.334 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.666 0.334 0.000
G44 Other headache syndromes
0.666 0.334 0.000
G50 Disorders of trigeminal nerve
0.666 0.334 0.000
Y57 Other and unspecified drugs and medicaments
0.665 0.335 0.000
S69 Other and unspecified injuries of wrist and hand
0.665 0.335 0.000
R29.6 Tendency to fall, not elsewhere classified
0.665 0.335 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.665 0.335 0.000
Z99.4 Dependence on artificial heart
0.665 0.335 0.000
Z99.0 Dependence on aspirator
0.665 0.335 0.000
S00.1 Contusion of eyelid and periocular area
0.665 0.335 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.665 0.335 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.336 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.664 0.336 0.000
Y84.1 Kidney dialysis
0.664 0.336 0.000
S00.7 Multiple superficial injuries of head
0.664 0.336 0.000
Z91.6 Personal history of other physical trauma
0.663 0.337 0.000
E40-E46 Malnutrition
0.662 0.338 0.000
S62.6 Fracture of other finger
0.661 0.338 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.660 0.340 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.660 0.340 0.000
I50 Heart failure
0.659 0.341 0.000
I49.8 Other specified cardiac arrhythmias
0.659 0.341 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.657 0.343 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.657 0.343 0.000
R41.1 Anterograde amnesia
0.657 0.343 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.656 0.343 0.000
G57.6 Lesion of plantar nerve
0.656 0.344 0.000
E22 Hyperfunction of pituitary gland
0.656 0.344 0.000
Z94.0 Kidney transplant status
0.656 0.344 0.000
R30-R39 Symptoms and signs involving the urinary system
0.656 0.344 0.000
S82 Fracture of lower leg, including ankle
0.652 0.347 0.000
R45.8 Other symptoms and signs involving emotional state
0.652 0.348 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.651 0.348 0.000
I12 Hypertensive renal disease
0.651 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.651 0.348 0.000
I51.5 Myocardial degeneration
0.651 0.349 0.000
I51.4 Myocarditis, unspecified
0.651 0.349 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.651 0.349 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.651 0.349 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.651 0.349 0.000
I51.0 Cardiac septal defect, acquired
0.651 0.349 0.000
G54 Nerve root and plexus disorders
0.650 0.349 0.000
Y43 Primarily systemic agents
0.650 0.350 0.000
Chapter VIII Diseases of the ear and mastoid process
0.649 0.351 0.000
L40 Psoriasis
0.648 0.352 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.648 0.352 0.000
R04 Haemorrhage from respiratory passages
0.648 0.352 0.000
G91 Hydrocephalus
0.648 0.352 0.000
S60 Superficial injury of wrist and hand
0.648 0.352 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.647 0.352 0.000
Z91.7 Personal history of female genital mutilation
0.647 0.352 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.647 0.352 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.647 0.352 0.000
Z91.2 Personal history of poor personal hygiene
0.647 0.352 0.000
R47-R49 Symptoms and signs involving speech and voice
0.647 0.352 0.000
Z74 Problems related to care-provider dependency
0.647 0.353 0.000
E87.3 Alkalosis
0.647 0.353 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.647 0.353 0.000
S68 Traumatic amputation of wrist and hand
0.647 0.353 0.000
G56.2 Lesion of ulnar nerve
0.647 0.353 0.000
T90.4 Sequelae of injury of eye and orbit
0.646 0.354 0.000
K75 Other inflammatory liver diseases
0.646 0.354 0.000
G56.0 Carpal tunnel syndrome
0.646 0.354 0.000
T43.2 Other and unspecified antidepressants
0.645 0.355 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.644 0.355 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.644 0.355 0.000
Q50-Q56 Congenital malformations of genital organs
0.644 0.355 0.000
Q35-Q37 Cleft lip and cleft palate
0.644 0.355 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.644 0.355 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.644 0.355 0.000
S89 Other and unspecified injuries of lower leg
0.644 0.356 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.644 0.356 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.644 0.356 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.644 0.356 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.644 0.356 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.644 0.356 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.644 0.356 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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