TreeWAS – Variant ID: rs11809180

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z34.8 Supervision of other normal pregnancy	0.017	0.983	0.000
Z34.0 Supervision of normal first pregnancy	0.012	0.988	0.000
Z34 Supervision of normal pregnancy	0.012	0.988	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.988	0.012
K83.8 Other specified diseases of biliary tract	0.000	0.989	0.011
K83 Other diseases of biliary tract	0.000	0.990	0.010
K83.1 Obstruction of bile duct	0.000	0.991	0.009
K83.0 Cholangitis	0.000	0.991	0.009
I69 Sequelae of cerebrovascular disease	0.000	0.992	0.008
N81.1 Cystocele	0.008	0.992	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.992	0.008
K83.9 Disease of biliary tract, unspecified	0.000	0.993	0.007
K83.5 Biliary cyst	0.000	0.993	0.007
K83.4 Spasm of sphincter of Oddi	0.000	0.993	0.007
K83.3 Fistula of bile duct	0.000	0.993	0.007
K83.2 Perforation of bile duct	0.000	0.993	0.007
I69.3 Sequelae of cerebral infarction	0.000	0.993	0.007
Z34.9 Supervision of normal pregnancy, unspecified	0.007	0.993	0.000
I67 Other cerebrovascular diseases	0.000	0.993	0.007
I67.2 Cerebral atherosclerosis	0.000	0.994	0.006
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.994	0.006
K81.0 Acute cholecystitis	0.000	0.994	0.006
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.994	0.006
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.994	0.006
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.994	0.005
O03.4 Incomplete, without complication	0.005	0.995	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.000	0.995	0.005
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.995	0.005
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.995	0.005
I67.5 Moyamoya disease	0.000	0.995	0.005
I67.4 Hypertensive encephalopathy	0.000	0.995	0.005
I67.3 Progressive vascular leukoencephalopathy	0.000	0.995	0.005
I67.8 Other specified cerebrovascular diseases	0.000	0.995	0.005
N88.8 Other specified noninflammatory disorders of cervix uteri	0.005	0.995	0.000
I60-I69 Cerebrovascular diseases	0.000	0.996	0.004
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.996	0.004
N88.2 Stricture and stenosis of cervix uteri	0.004	0.996	0.000
O02.1 Missed abortion	0.004	0.996	0.000
K81 Cholecystitis	0.000	0.996	0.004
H80.9 Otosclerosis, unspecified	0.004	0.996	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
N88 Other noninflammatory disorders of cervix uteri	0.003	0.997	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.003
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.997	0.003
O03 Spontaneous abortion	0.003	0.997	0.000
H83.0 Labyrinthitis	0.003	0.997	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
O80.9 Single spontaneous delivery, unspecified	0.003	0.997	0.000
L89.1 Stage II decubitus ulcer	0.000	0.997	0.003
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.997	0.003
H80 Otosclerosis	0.003	0.997	0.000
O02 Other abnormal products of conception	0.003	0.997	0.000
C50.1 Central portion of breast	0.003	0.997	0.000
H61.2 Impacted cerumen	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
H83 Other diseases of inner ear	0.003	0.997	0.000
A04.8 Other specified bacterial intestinal infections	0.003	0.997	0.000
K81.8 Other cholecystitis	0.000	0.997	0.003
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.997	0.003
D68 Other coagulation defects	0.000	0.997	0.003
H80-H83 Diseases of inner ear	0.003	0.997	0.000
H61 Other disorders of external ear	0.003	0.997	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.003	0.997	0.000
N88.3 Incompetence of cervix uteri	0.003	0.997	0.000
N88.1 Old laceration of cervix uteri	0.003	0.997	0.000
N88.0 Leukoplakia of cervix uteri	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.000	0.997	0.003
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.003	0.997	0.000
D22.5 Melanocytic naevi of trunk	0.003	0.997	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.997	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.997	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.997	0.002
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.997	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.997	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.997	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.997	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.997	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.997	0.002
O03.8 Complete or unspecified, with other and unspecified complications	0.003	0.997	0.000
O03.7 Complete or unspecified, complicated by embolism	0.003	0.997	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.003	0.997	0.000
O03.3 Incomplete, with other and unspecified complications	0.003	0.997	0.000
O03.2 Incomplete, complicated by embolism	0.003	0.997	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.003	0.997	0.000
O00-O08 Pregnancy with abortive outcome	0.003	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.997	0.003
I63 Cerebral infarction	0.000	0.997	0.003
I60 Subarachnoid haemorrhage	0.000	0.997	0.003
H60-H62 Diseases of external ear	0.003	0.997	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.997	0.002
D68.8 Other specified coagulation defects	0.000	0.997	0.002
H80.8 Other otosclerosis	0.002	0.997	0.000
H80.2 Cochlear otosclerosis	0.002	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.997	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.997	0.002
Y42.5 Other oestrogens and progestogens	0.002	0.997	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
K82 Other diseases of gallbladder	0.000	0.998	0.002
O02.9 Abnormal product of conception, unspecified	0.002	0.998	0.000
O02.8 Other specified abnormal products of conception	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
W10.8 Other specified place	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.998	0.002
K85 Acute pancreatitis	0.000	0.998	0.002
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
N81.6 Rectocele	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
H66 Suppurative and unspecified otitis media	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.002
K82.9 Disease of gallbladder, unspecified	0.000	0.998	0.002
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.998	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O07 Failed attempted abortion	0.002	0.998	0.000
O06 Unspecified abortion	0.002	0.998	0.000
O05 Other abortion	0.002	0.998	0.000
O01 Hydatidiform mole	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
N81.3 Complete uterovaginal prolapse	0.002	0.998	0.000
K81.1 Chronic cholecystitis	0.000	0.998	0.002
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
O04 Medical abortion	0.002	0.998	0.000
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
H92.1 Otorrhoea	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
Z46.6 Fitting and adjustment of urinary device	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
O00 Ectopic pregnancy	0.002	0.998	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.998	0.002
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.002
O04.4 Incomplete, without complication	0.002	0.998	0.000
O80 Single spontaneous delivery	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
K82.3 Fistula of gallbladder	0.000	0.998	0.002
K82.0 Obstruction of gallbladder	0.000	0.998	0.002
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.002	0.998	0.000
G95 Other diseases of spinal cord	0.000	0.998	0.002
N81 Female genital prolapse	0.002	0.998	0.000
Z46 Fitting and adjustment of other devices	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
K85.8 Other acute pancreatitis	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.000	0.998	0.002
K85.2 Alcohol-induced acute pancreatitis	0.000	0.998	0.002
K85.0 Idiopathic acute pancreatitis	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.002
K82.1 Hydrops of gallbladder	0.000	0.998	0.002
R19.4 Change in bowel habit	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
M75.4 Impingement syndrome of shoulder	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
K82.8 Other specified diseases of gallbladder	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.998	0.002
O01.9 Hydatidiform mole, unspecified	0.002	0.998	0.000
O01.1 Incomplete and partial hydatidiform mole	0.002	0.998	0.000
O01.0 Classical hydatidiform mole	0.002	0.998	0.000
O05.9 Complete or unspecified, without complication	0.002	0.998	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O05.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O05.4 Incomplete, without complication	0.002	0.998	0.000
O05.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O05.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O06.9 Complete or unspecified, without complication	0.002	0.998	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O06.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O06.4 Incomplete, without complication	0.002	0.998	0.000
O06.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O06.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.002	0.998	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.002	0.998	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.002	0.998	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O07.4 Failed medical abortion, without complication	0.002	0.998	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.002	0.998	0.000
O07.2 Failed medical abortion, complicated by embolism	0.002	0.998	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.002	0.998	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
A04 Other bacterial intestinal infections	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
I63.8 Other cerebral infarction	0.000	0.998	0.002
Z46.7 Fitting and adjustment of orthopaedic device	0.002	0.998	0.000
I61 Intracerebral haemorrhage	0.001	0.998	0.001
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O04.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O04.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O04.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O80.8 Other single spontaneous delivery	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
K05.6 Periodontal disease, unspecified	0.002	0.998	0.000
O00.9 Ectopic pregnancy, unspecified	0.002	0.998	0.000
O00.8 Other ectopic pregnancy	0.002	0.998	0.000
O00.2 Ovarian pregnancy	0.002	0.998	0.000
O00.0 Abdominal pregnancy	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
F41.2 Mixed anxiety and depressive disorder	0.002	0.998	0.000
K82.2 Perforation of gallbladder	0.000	0.998	0.002
O80.1 Spontaneous breech delivery	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
L89 Decubitus ulcer	0.000	0.998	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.001
K62.8 Other specified diseases of anus and rectum	0.002	0.998	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.002	0.998	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.002	0.998	0.000
Z46.1 Fitting and adjustment of hearing aid	0.002	0.998	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.002	0.998	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.998	0.002
Z04.8 Examination and observation for other specified reasons	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
N81.0 Female urethrocele	0.002	0.998	0.000
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
O82 Single delivery by Caesarean section	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.002	0.998	0.000
W10 Fall on and from stairs and steps	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.001	0.998	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.998	0.002
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.001	0.998	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.998	0.001
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.001	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
H92 Otalgia and effusion of ear	0.001	0.998	0.000
A04.9 Bacterial intestinal infection, unspecified	0.001	0.998	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.001	0.998	0.000
A04.4 Other intestinal Escherichia coli infections	0.001	0.998	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.001	0.998	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.001	0.998	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.001	0.998	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.001	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.998	0.001
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
H81.8 Other disorders of vestibular function	0.001	0.998	0.000
H81.4 Vertigo of central origin	0.001	0.998	0.000
H81.3 Other peripheral vertigo	0.001	0.998	0.000
I61.8 Other intracerebral haemorrhage	0.001	0.998	0.001
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.998	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.998	0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.998	0.001
Y40.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
Y40.6 Rifamycins	0.001	0.998	0.000
Y40.5 Aminoglycosides	0.001	0.998	0.000
Y40.4 Tetracyclines	0.001	0.998	0.000
Y40.2 Chloramphenicol group	0.001	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.001	0.998	0.000
Y47.1 Benzodiazepines	0.001	0.998	0.000
H73 Other disorders of tympanic membrane	0.001	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.998	0.000
S02.60 Fracture of mandible (closed)	0.001	0.998	0.000
L89.2 Stage III decubitus ulcer	0.000	0.998	0.001
O82.1 Delivery by emergency Caesarean section	0.001	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.001	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.998	0.000
Y45.1 Salicylates	0.001	0.998	0.000
Z39.1 Care and examination of lactating mother	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.001	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.001	0.998	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.998	0.001
N81.9 Female genital prolapse, unspecified	0.001	0.998	0.000
S02.6 Fracture of mandible	0.001	0.998	0.000
Z46.8 Fitting and adjustment of other specified devices	0.001	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.001	0.998	0.000
G95.1 Vascular myelopathies	0.000	0.998	0.001
H81.1 Benign paroxysmal vertigo	0.001	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.001	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.001	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.001	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.001	0.998	0.000
C67.2 Lateral wall of bladder	0.000	0.998	0.001
H70.9 Mastoiditis, unspecified	0.001	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.998	0.001
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.998	0.001
S06.5 Traumatic subdural haemorrhage	0.001	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.001	0.998	0.000
Y40.3 Macrolides	0.001	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.001
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.998	0.001
O82.9 Delivery by Caesarean section, unspecified	0.001	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.001	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.001	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.001	0.998	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.998	0.000
Y58 Bacterial vaccines	0.001	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.998	0.000
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000
G93.3 Postviral fatigue syndrome	0.000	0.999	0.001
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000
H70.2 Petrositis	0.001	0.999	0.000
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.001
W10.4 Street and highway	0.001	0.999	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.001	0.999	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.999	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.001	0.999	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.001	0.999	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.001	0.999	0.000
H74.1 Adhesive middle ear disease	0.001	0.999	0.000
H90.2 Conductive hearing loss, unspecified	0.001	0.999	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.999	0.001
K65.0 Acute peritonitis	0.000	0.999	0.001
S02.8 Fractures of other skull and facial bones	0.001	0.999	0.000
W10.9 Unspecified place	0.001	0.999	0.000
W10.5 Trade and service area	0.001	0.999	0.000
W10.2 School, other institution and public administrative area	0.001	0.999	0.000
W10.0 Home	0.001	0.999	0.000
W10.7 Farm	0.001	0.999	0.000
W10.6 Industrial and construction area	0.001	0.999	0.000
W10.3 Sports and athletics area	0.001	0.999	0.000
W10.1 Residential institution	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.001	0.999	0.000
Y57 Other and unspecified drugs and medicaments	0.001	0.999	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.999	0.001
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.999	0.001
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.999	0.001
Y43.3 Other antineoplastic drugs	0.000	0.999	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.999	0.000
Y45.5 4-Aminophenol derivatives	0.001	0.999	0.000
Y45.4 Antirheumatics	0.001	0.999	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
H92.2 Otorrhagia	0.001	0.999	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.999	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.999	0.000
Y47.4 Bromine compounds	0.001	0.999	0.000
Y47.3 Paraldehyde	0.001	0.999	0.000
Y47.2 Chloral derivatives	0.001	0.999	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.999	0.000
O84 Multiple delivery	0.001	0.999	0.000
O83 Other assisted single delivery	0.001	0.999	0.000
O81 Single delivery by forceps and vacuum extractor	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
Y45.0 Opioids and related analgesics	0.001	0.999	0.000
O16 Unspecified maternal hypertension	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.001	0.999	0.000
H73.1 Chronic myringitis	0.001	0.999	0.000
H73.0 Acute myringitis	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.001	0.999	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations