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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118141139
log Bayes Factor = 12.2839
Chromosome 14   position 96,787,278  (GRCh37) Explore rs118141139 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
N00-N08 Glomerular diseases
0.990 0.010 0.000
K62 Other diseases of anus and rectum
0.990 0.010 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.990 0.010 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.985 0.015 0.000
N18.9 Chronic renal failure, unspecified
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
E10-E14 Diabetes mellitus
0.984 0.016 0.000
K50-K52 Noninfective enteritis and colitis
0.976 0.024 0.000
H30-H36 Disorders of choroid and retina
0.971 0.029 0.000
N18.5 Chronic kidney disease, stage 5
0.963 0.037 0.000
E65-E68 Obesity and other hyperalimentation
0.962 0.038 0.000
M05-M14 Inflammatory polyarthropathies
0.961 0.039 0.000
K62.3 Rectal prolapse
0.960 0.040 0.000
H02 Other disorders of eyelid
0.957 0.043 0.000
M65-M68 Disorders of synovium and tendon
0.954 0.046 0.000
H04 Disorders of lachrymal system
0.953 0.047 0.000
K56.6 Other and unspecified intestinal obstruction
0.953 0.047 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.952 0.048 0.000
K50 Crohn's disease [regional enteritis]
0.948 0.052 0.000
N03 Chronic nephritic syndrome
0.943 0.057 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.941 0.059 0.000
E50-E64 Other nutritional deficiencies
0.938 0.062 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.936 0.064 0.000
E66 Obesity
0.935 0.065 0.000
E11 Non-insulin-dependent diabetes mellitus
0.934 0.066 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.934 0.066 0.000
H35 Other retinal disorders
0.931 0.069 0.000
K59 Other functional intestinal disorders
0.928 0.072 0.000
E00-E07 Disorders of thyroid gland
0.928 0.072 0.000
N18.3 Chronic kidney disease, stage 3
0.926 0.074 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.926 0.074 0.000
M67 Other disorders of synovium and tendon
0.926 0.074 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.915 0.085 0.000
N17 Acute renal failure
0.914 0.086 0.000
N03.9 Unspecified
0.909 0.091 0.000
H02.0 Entropion and trichiasis of eyelid
0.909 0.091 0.000
E10 Insulin-dependent diabetes mellitus
0.904 0.096 0.000
M67.8 Other specified disorders of synovium and tendon
0.903 0.097 0.000
E66.9 Obesity, unspecified
0.901 0.099 0.000
M06 Other rheumatoid arthritis
0.901 0.099 0.000
E11.3 With ophthalmic complications
0.890 0.110 0.000
Y84.2 Radiological procedure and radiotherapy
0.889 0.111 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.888 0.112 0.000
Chapter II Neoplasms
0.885 0.115 0.000
H36 Retinal disorders in diseases classified elsewhere
0.884 0.116 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.883 0.117 0.000
K82 Other diseases of gallbladder
0.879 0.121 0.000
Chapter IX Diseases of the circulatory system
0.875 0.125 0.000
K62.0 Anal polyp
0.874 0.126 0.000
N20-N23 Urolithiasis
0.874 0.126 0.000
K51 Ulcerative colitis
0.873 0.127 0.000
N18.0 End-stage renal disease
0.871 0.129 0.000
M86-M90 Other osteopathies
0.870 0.130 0.000
K61 Abscess of anal and rectal regions
0.859 0.140 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.859 0.141 0.000
H02.4 Ptosis of eyelid
0.854 0.146 0.000
K65-K67 Diseases of peritoneum
0.852 0.148 0.000
N19 Unspecified renal failure
0.849 0.151 0.000
E03 Other hypothyroidism
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
K50.0 Crohn's disease of small intestine
0.846 0.154 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.846 0.154 0.000
E53 Deficiency of other B group vitamins
0.845 0.155 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.844 0.156 0.000
K62.4 Stenosis of anus and rectum
0.843 0.157 0.000
N17.9 Acute renal failure, unspecified
0.836 0.164 0.000
H35.3 Degeneration of macula and posterior pole
0.834 0.166 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.833 0.167 0.000
K90-K93 Other diseases of the digestive system
0.832 0.168 0.000
K81 Cholecystitis
0.831 0.169 0.000
K59.0 Constipation
0.830 0.170 0.000
K50.9 Crohn's disease, unspecified
0.825 0.175 0.000
H02.1 Ectropion of eyelid
0.825 0.175 0.000
H36.0 Diabetic retinopathy
0.821 0.179 0.000
Y95 Nosocomial condition
0.819 0.181 0.000
E61 Deficiency of other nutrient elements
0.819 0.181 0.000
K55 Vascular disorders of intestine
0.818 0.182 0.000
E20-E35 Disorders of other endocrine glands
0.818 0.182 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.814 0.186 0.000
E11.2 With renal complications
0.812 0.188 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.812 0.188 0.000
K83 Other diseases of biliary tract
0.812 0.188 0.000
M80-M85 Disorders of bone density and structure
0.811 0.189 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.811 0.189 0.000
V20-V29 Motorcycle rider injured in transport accident
0.810 0.189 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.810 0.190 0.000
H35.0 Background retinopathy and retinal vascular changes
0.808 0.192 0.000
Chapter XXII Codes for special purposes
0.806 0.194 0.000
M70-M79 Other soft tissue disorders
0.804 0.196 0.000
I10-I15 Hypertensive diseases
0.802 0.198 0.000
K62.6 Ulcer of anus and rectum
0.799 0.200 0.000
M20-M25 Other joint disorders
0.799 0.201 0.000
K81.1 Chronic cholecystitis
0.798 0.202 0.000
N04 Nephrotic syndrome
0.796 0.203 0.000
M11 Other crystal arthropathies
0.794 0.206 0.000
E03.9 Hypothyroidism, unspecified
0.789 0.211 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.789 0.211 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.782 0.218 0.000
M91-M94 Chondropathies
0.780 0.220 0.000
E53.8 Deficiency of other specified B group vitamins
0.779 0.221 0.000
M06.9 Rheumatoid arthritis, unspecified
0.779 0.221 0.000
Y84.6 Urinary catheterisation
0.779 0.221 0.000
M06.0 Seronegative rheumatoid arthritis
0.779 0.221 0.000
H04.2 Epiphora
0.778 0.222 0.000
K50.1 Crohn's disease of large intestine
0.776 0.224 0.000
M45-M49 Spondylopathies
0.776 0.224 0.000
K50.8 Other Crohn's disease
0.775 0.225 0.000
K56.2 Volvulus
0.775 0.225 0.000
H04.8 Other disorders of lachrymal system
0.775 0.225 0.000
D00-D09 In situ neoplasms
0.772 0.228 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.771 0.229 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.770 0.230 0.000
Chapter I Certain infectious and parasitic diseases
0.769 0.231 0.000
E11.5 With peripheral circulatory complications
0.769 0.231 0.000
I12 Hypertensive renal disease
0.768 0.232 0.000
H02.3 Blepharochalasis
0.765 0.235 0.000
K82.4 Cholesterolosis of gallbladder
0.765 0.235 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.764 0.236 0.000
E10.9 Without complications
0.764 0.236 0.000
K59.9 Functional intestinal disorder, unspecified
0.764 0.236 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.761 0.239 0.000
K35-K38 Diseases of appendix
0.761 0.239 0.000
E66.0 Obesity due to excess calories
0.758 0.242 0.000
N87 Dysplasia of cervix uteri
0.757 0.243 0.000
L20-L30 Dermatitis and eczema
0.756 0.244 0.000
H05 Disorders of orbit
0.754 0.246 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.754 0.246 0.000
K61.0 Anal abscess
0.751 0.249 0.000
H55-H59 Other disorders of eye and adnexa
0.750 0.249 0.000
H04.1 Other disorders of lachrymal gland
0.749 0.251 0.000
N10-N16 Renal tubulo-interstitial diseases
0.748 0.252 0.000
N23 Unspecified renal colic
0.746 0.254 0.000
E13 Other specified diabetes mellitus
0.745 0.255 0.000
E10.3 With ophthalmic complications
0.745 0.255 0.000
L40-L45 Papulosquamous disorders
0.745 0.255 0.000
I12.0 Hypertensive renal disease with renal failure
0.745 0.255 0.000
Y84.0 Cardiac catheterisation
0.744 0.256 0.000
K62.7 Radiation proctitis
0.744 0.256 0.000
K59.1 Functional diarrhoea
0.742 0.258 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.741 0.259 0.000
H35.8 Other specified retinal disorders
0.741 0.259 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.739 0.261 0.000
M14 Arthropathies in other diseases classified elsewhere
0.735 0.265 0.000
E61.1 Iron deficiency
0.734 0.266 0.000
K51.9 Ulcerative colitis, unspecified
0.734 0.266 0.000
H33 Retinal detachments and breaks
0.732 0.268 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.732 0.268 0.000
K55.9 Vascular disorder of intestine, unspecified
0.731 0.269 0.000
I05-I09 Chronic rheumatic heart diseases
0.731 0.269 0.000
N81 Female genital prolapse
0.729 0.271 0.000
K82.8 Other specified diseases of gallbladder
0.729 0.271 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.729 0.271 0.000
K56.1 Intussusception
0.727 0.273 0.000
M86 Osteomyelitis
0.726 0.273 0.000
M00-M03 Infectious arthropathies
0.725 0.275 0.000
X60-X84 Intentional self-harm
0.725 0.275 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.723 0.277 0.000
X20-X29 Contact with venomous animals and plants
0.723 0.277 0.000
M79.8 Other specified soft tissue disorders
0.722 0.278 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.721 0.279 0.000
H43-H45 Disorders of vitreous body and globe
0.721 0.279 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.721 0.279 0.000
M10 Gout
0.721 0.279 0.000
Y84.8 Other medical procedures
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
N18.8 Other chronic renal failure
0.717 0.283 0.000
N18.1 Chronic kidney disease, stage 1
0.717 0.283 0.000
N25-N29 Other disorders of kidney and ureter
0.716 0.284 0.000
E14 Unspecified diabetes mellitus
0.716 0.284 0.000
C32 Malignant neoplasm of larynx
0.716 0.284 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M06.4 Inflammatory polyarthropathy
0.713 0.287 0.000
E06 Thyroiditis
0.713 0.287 0.000
N18.4 Chronic kidney disease, stage 4
0.713 0.287 0.000
H02.6 Xanthelasma of eyelid
0.713 0.287 0.000
N99-N99 Other disorders of the genitourinary system
0.712 0.288 0.000
N18.2 Chronic kidney disease, stage 2
0.711 0.288 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.710 0.290 0.000
N06 Isolated proteinuria with specified morphological lesion
0.710 0.290 0.000
N05 Unspecified nephritic syndrome
0.710 0.290 0.000
N01 Rapidly progressive nephritic syndrome
0.710 0.290 0.000
N00 Acute nephritic syndrome
0.710 0.290 0.000
K56.3 Gallstone ileus
0.710 0.290 0.000
K56.0 Paralytic ileus
0.710 0.290 0.000
K62.2 Anal prolapse
0.710 0.290 0.000
K66 Other disorders of peritoneum
0.709 0.291 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.709 0.291 0.000
E10.4 With neurological complications
0.708 0.292 0.000
N17.0 Acute renal failure with tubular necrosis
0.708 0.292 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.707 0.293 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.706 0.294 0.000
M05 Seropositive rheumatoid arthritis
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
E12 Malnutrition-related diabetes mellitus
0.705 0.295 0.000
K86 Other diseases of pancreas
0.705 0.295 0.000
E66.8 Other obesity
0.705 0.295 0.000
K59.3 Megacolon, not elsewhere classified
0.703 0.297 0.000
K63 Other diseases of intestine
0.702 0.298 0.000
N73 Other female pelvic inflammatory diseases
0.702 0.298 0.000
K56.7 Ileus, unspecified
0.700 0.300 0.000
N21 Calculus of lower urinary tract
0.700 0.300 0.000
H35.4 Peripheral retinal degeneration
0.699 0.301 0.000
E04 Other non-toxic goitre
0.697 0.302 0.000
E40-E46 Malnutrition
0.697 0.303 0.000
N87.1 Moderate cervical dysplasia
0.696 0.304 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.696 0.304 0.000
H31 Other disorders of choroid
0.696 0.304 0.000
H30 Chorioretinal inflammation
0.696 0.304 0.000
K62.5 Haemorrhage of anus and rectum
0.695 0.305 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.694 0.306 0.000
I95 Hypotension
0.693 0.307 0.000
Y40 Systemic antibiotics
0.692 0.308 0.000
M67.1 Other contracture of tendon (sheath)
0.692 0.308 0.000
K82.2 Perforation of gallbladder
0.692 0.308 0.000
K83.8 Other specified diseases of biliary tract
0.691 0.309 0.000
B35-B49 Mycoses
0.690 0.310 0.000
E67 Other hyperalimentation
0.690 0.310 0.000
E68 Sequelae of hyperalimentation
0.690 0.310 0.000
E65 Localised adiposity
0.690 0.310 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.689 0.311 0.000
M12 Other specific arthropathies
0.689 0.311 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.689 0.311 0.000
M08 Juvenile arthritis
0.689 0.311 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.689 0.311 0.000
M07 Psoriatic and enteropathic arthropathies
0.688 0.312 0.000
K85 Acute pancreatitis
0.688 0.312 0.000
N81.8 Other female genital prolapse
0.688 0.312 0.000
N02 Recurrent and persistent haematuria
0.687 0.313 0.000
C34 Malignant neoplasm of bronchus and lung
0.687 0.313 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.686 0.313 0.000
W20-W49 Exposure to inanimate mechanical forces
0.686 0.314 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.686 0.314 0.000
H02.2 Lagophthalmos
0.686 0.314 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
E10.1 With ketoacidosis
0.685 0.315 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.684 0.316 0.000
D60-D64 Aplastic and other anaemias
0.684 0.316 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.684 0.316 0.000
M66 Spontaneous rupture of synovium and tendon
0.684 0.316 0.000
E07 Other disorders of thyroid
0.683 0.316 0.000
H04.9 Disorder of lachrymal system, unspecified
0.683 0.317 0.000
H04.6 Other changes in lachrymal passages
0.683 0.317 0.000
H04.4 Chronic inflammation of lachrymal passages
0.683 0.317 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.683 0.317 0.000
H04.0 Dacryoadenitis
0.683 0.317 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.683 0.317 0.000
E11.1 With ketoacidosis
0.683 0.317 0.000
L50-L54 Urticaria and erythema
0.683 0.317 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.682 0.318 0.000
K62.8 Other specified diseases of anus and rectum
0.678 0.322 0.000
M21 Other acquired deformities of limbs
0.678 0.322 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.678 0.322 0.000
M84 Disorders of continuity of bone
0.678 0.322 0.000
M13 Other arthritis
0.677 0.323 0.000
H10-H13 Disorders of conjunctiva
0.676 0.323 0.000
N03.8 Other
0.676 0.324 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.676 0.324 0.000
N03.6 Dense deposit disease
0.676 0.324 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.676 0.324 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.676 0.324 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.676 0.324 0.000
N03.2 Diffuse membranous glomerulonephritis
0.676 0.324 0.000
N03.1 Focal and segmental glomerular lesions
0.676 0.324 0.000
N03.0 Minor glomerular abnormality
0.676 0.324 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.676 0.324 0.000
K90 Intestinal malabsorption
0.676 0.324 0.000
M11.2 Other chondrocalcinosis
0.674 0.326 0.000
E11.4 With neurological complications
0.674 0.326 0.000
K65 Peritonitis
0.674 0.326 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.672 0.328 0.000
E63 Other nutritional deficiencies
0.672 0.328 0.000
E56 Other vitamin deficiencies
0.672 0.328 0.000
E51 Thiamine deficiency
0.672 0.328 0.000
E50 Vitamin A deficiency
0.672 0.328 0.000
E60 Dietary zinc deficiency
0.672 0.328 0.000
E59 Dietary selenium deficiency
0.672 0.328 0.000
E58 Dietary calcium deficiency
0.672 0.328 0.000
E54 Ascorbic acid deficiency
0.672 0.328 0.000
E52 Niacin deficiency [pellagra]
0.672 0.328 0.000
Y57 Other and unspecified drugs and medicaments
0.672 0.328 0.000
K83.1 Obstruction of bile duct
0.672 0.328 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.672 0.328 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.670 0.330 0.000
Chapter VI Diseases of the nervous system
0.670 0.330 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.670 0.330 0.000
E66.1 Drug-induced obesity
0.670 0.330 0.000
E11.8 With unspecified complications
0.670 0.330 0.000
E11.7 With multiple complications
0.670 0.330 0.000
E11.6 With other specified complications
0.670 0.330 0.000
E11.0 With coma
0.670 0.330 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.670 0.330 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.670 0.330 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.670 0.330 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.670 0.330 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.670 0.330 0.000
M47 Spondylosis
0.668 0.332 0.000
H35.9 Retinal disorder, unspecified
0.667 0.333 0.000
H35.7 Separation of retinal layers
0.667 0.333 0.000
H35.6 Retinal haemorrhage
0.667 0.333 0.000
H35.5 Hereditary retinal dystrophy
0.667 0.333 0.000
H35.2 Other proliferative retinopathy
0.667 0.333 0.000
H35.1 Retinopathy of prematurity
0.667 0.333 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.667 0.333 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.666 0.333 0.000
L05 Pilonidal cyst
0.666 0.334 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.665 0.335 0.000
K59.4 Anal spasm
0.665 0.335 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.665 0.335 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.665 0.335 0.000
E00 Congenital iodine-deficiency syndrome
0.665 0.335 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.335 0.000
D48.7 Other specified sites
0.665 0.335 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.664 0.336 0.000
M67.4 Ganglion
0.664 0.336 0.000
M67.3 Transient synovitis
0.664 0.336 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.664 0.336 0.000
M67.0 Short Achilles tendon (acquired)
0.664 0.336 0.000
Y84.9 Medical procedure, unspecified
0.664 0.336 0.000
Y84.7 Blood-sampling
0.664 0.336 0.000
Y84.5 Insertion of gastric or duodenal sound
0.664 0.336 0.000
Y84.4 Aspiration of fluid
0.664 0.336 0.000
Y84.3 Shock therapy
0.664 0.336 0.000
Y84.1 Kidney dialysis
0.664 0.336 0.000
H02.5 Other disorders affecting eyelid function
0.662 0.337 0.000
N73.6 Female pelvic peritoneal adhesions
0.660 0.340 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.659 0.341 0.000
K62.1 Rectal polyp
0.659 0.341 0.000
Q80-Q89 Other congenital malformations
0.659 0.341 0.000
M88 Paget's disease of bone [osteitis deformans]
0.658 0.341 0.000
N04.9 Unspecified
0.658 0.342 0.000
N89 Other noninflammatory disorders of vagina
0.658 0.342 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.657 0.343 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.656 0.344 0.000
L10-L14 Bullous disorders
0.656 0.344 0.000
Chapter X Diseases of the respiratory system
0.656 0.344 0.000
N17.8 Other acute renal failure
0.655 0.345 0.000
N17.2 Acute renal failure with medullary necrosis
0.655 0.345 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.655 0.345 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
M65 Synovitis and tenosynovitis
0.654 0.346 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.653 0.347 0.000
E55 Vitamin D deficiency
0.652 0.348 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.651 0.349 0.000
M40-M43 Deforming dorsopathies
0.651 0.349 0.000
M90 Osteopathies in diseases classified elsewhere
0.650 0.349 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.650 0.350 0.000
I15 Secondary hypertension
0.649 0.351 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.648 0.351 0.000
E10.8 With unspecified complications
0.648 0.352 0.000
E10.7 With multiple complications
0.648 0.352 0.000
E10.6 With other specified complications
0.648 0.352 0.000
E10.5 With peripheral circulatory complications
0.648 0.352 0.000
E10.2 With renal complications
0.648 0.352 0.000
E10.0 With coma
0.648 0.352 0.000
M89 Other disorders of bone
0.647 0.353 0.000
M06.8 Other specified rheumatoid arthritis
0.646 0.354 0.000
M06.3 Rheumatoid nodule
0.646 0.354 0.000
M06.2 Rheumatoid bursitis
0.646 0.354 0.000
M06.1 Adult-onset Still's disease
0.646 0.354 0.000
C64-C68 Malignant neoplasms of urinary tract
0.642 0.358 0.000
N13 Obstructive and reflux uropathy
0.642 0.358 0.000
M87 Osteonecrosis
0.642 0.358 0.000
D05 Carcinoma in situ of breast
0.641 0.359 0.000
Q00-Q07 Congenital malformations of the nervous system
0.639 0.360 0.000
M23 Internal derangement of knee
0.639 0.361 0.000
M50-M54 Other dorsopathies
0.638 0.362 0.000
D48.1 Connective and other soft tissue
0.638 0.362 0.000
M32 Systemic lupus erythematosus
0.638 0.362 0.000
L85 Other epidermal thickening
0.637 0.363 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.637 0.363 0.000
E14.3 With ophthalmic complications
0.637 0.363 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.637 0.363 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.637 0.363 0.000
Y98 Lifestyle-related condition
0.637 0.363 0.000
Y97 Environmental-pollution-related condition
0.637 0.363 0.000
Y96 Work-related condition
0.637 0.363 0.000
I11 Hypertensive heart disease
0.636 0.364 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.636 0.364 0.000
N80 Endometriosis
0.636 0.364 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.636 0.364 0.000
D80-D89 Certain disorders involving the immune mechanism
0.635 0.365 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.634 0.365 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.634 0.365 0.000
K61.3 Ischiorectal abscess
0.634 0.366 0.000
I30-I52 Other forms of heart disease
0.634 0.366 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.633 0.366 0.000
L43 Lichen planus
0.633 0.367 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.632 0.368 0.000
L29 Pruritus
0.631 0.369 0.000
N94.6 Dysmenorrhoea, unspecified
0.631 0.369 0.000
K82.9 Disease of gallbladder, unspecified
0.630 0.370 0.000
K82.3 Fistula of gallbladder
0.630 0.370 0.000
K82.1 Hydrops of gallbladder
0.630 0.370 0.000
K82.0 Obstruction of gallbladder
0.630 0.370 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.630 0.370 0.000
L89 Decubitus ulcer
0.630 0.370 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.628 0.372 0.000
H01 Other inflammation of eyelid
0.628 0.372 0.000
H33.0 Retinal detachment with retinal break
0.628 0.372 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.628 0.372 0.000
K62.9 Disease of anus and rectum, unspecified
0.628 0.372 0.000
I00-I02 Acute rheumatic fever
0.627 0.373 0.000
Y44 Agents primarily affecting blood constituents
0.627 0.373 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.626 0.373 0.000
M80 Osteoporosis with pathological fracture
0.626 0.374 0.000
K56.4 Other impaction of intestine
0.626 0.374 0.000
K51.5 Mucosal proctocolitis
0.626 0.374 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.626 0.374 0.000
N71 Inflammatory disease of uterus, except cervix
0.625 0.375 0.000
M22 Disorders of patella
0.625 0.375 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.624 0.376 0.000
N20 Calculus of kidney and ureter
0.624 0.376 0.000
N93 Other abnormal uterine and vaginal bleeding
0.624 0.376 0.000
M86.9 Osteomyelitis, unspecified
0.624 0.376 0.000
M93 Other osteochondropathies
0.623 0.376 0.000
I08 Multiple valve diseases
0.622 0.378 0.000
N81.9 Female genital prolapse, unspecified
0.621 0.379 0.000
K51.4 Pseudopolyposis of colon
0.620 0.379 0.000
M85 Other disorders of bone density and structure
0.620 0.380 0.000
K91.4 Colostomy and enterostomy malfunction
0.620 0.380 0.000
N81.4 Uterovaginal prolapse, unspecified
0.620 0.380 0.000
J95-J99 Other diseases of the respiratory system
0.620 0.380 0.000
C50-C50 Malignant neoplasm of breast
0.619 0.381 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.619 0.381 0.000
C51-C58 Malignant neoplasms of female genital organs
0.619 0.381 0.000
M24 Other specific joint derangements
0.618 0.382 0.000
D47.2 Monoclonal gammopathy
0.618 0.382 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.618 0.382 0.000
H18 Other disorders of cornea
0.617 0.383 0.000
C73 Malignant neoplasm of thyroid gland
0.617 0.383 0.000
K61.4 Intrasphincteric abscess
0.616 0.384 0.000
K61.2 Anorectal abscess
0.616 0.384 0.000
K61.1 Rectal abscess
0.616 0.384 0.000
Y59 Other and unspecified vaccines and biological substances
0.616 0.384 0.000
Y58 Bacterial vaccines
0.616 0.384 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.616 0.384 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.616 0.384 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.616 0.384 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.616 0.384 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.616 0.384 0.000
Y48 Anaesthetics and therapeutic gases
0.616 0.384 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.616 0.384 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.616 0.384 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.616 0.384 0.000
L83 Acanthosis nigricans
0.615 0.385 0.000
M77 Other enthesopathies
0.614 0.385 0.000
D46 Myelodysplastic syndromes
0.614 0.386 0.000
N94.1 Dyspareunia
0.613 0.387 0.000
E22 Hyperfunction of pituitary gland
0.613 0.387 0.000
C32.0 Glottis
0.611 0.389 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.611 0.389 0.000
H46 Optic neuritis
0.611 0.389 0.000
M47.8 Other spondylosis
0.610 0.390 0.000
C34.3 Lower lobe, bronchus or lung
0.609 0.391 0.000
Y45.0 Opioids and related analgesics
0.608 0.392 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.608 0.392 0.000
E03.8 Other specified hypothyroidism
0.607 0.393 0.000
E03.5 Myxoedema coma
0.607 0.393 0.000
E03.4 Atrophy of thyroid (acquired)
0.607 0.393 0.000
E03.3 Postinfectious hypothyroidism
0.607 0.393 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.607 0.393 0.000
E03.1 Congenital hypothyroidism without goitre
0.607 0.393 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.607 0.393 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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