TreeWAS – Variant ID: rs11825181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.769	0.231	0.000
E78.2 Mixed hyperlipidaemia	0.694	0.306	0.000
E78.4 Other hyperlipidaemia	0.667	0.333	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.617	0.383	0.000
E78.1 Pure hyperglyceridaemia	0.570	0.430	0.000
E78.6 Lipoprotein deficiency	0.551	0.449	0.000
E78.3 Hyperchylomicronaemia	0.551	0.449	0.000
E78.8 Other disorders of lipoprotein metabolism	0.533	0.467	0.000
E78.5 Hyperlipidaemia, unspecified	0.338	0.662	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.962	0.038
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.963	0.037
C78.0 Secondary malignant neoplasm of lung	0.000	0.965	0.035
I63.9 Cerebral infarction, unspecified	0.000	0.965	0.035
C78.7 Secondary malignant neoplasm of liver	0.000	0.965	0.035
I63 Cerebral infarction	0.000	0.966	0.034
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.968	0.032
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.969	0.031
I60-I69 Cerebrovascular diseases	0.000	0.971	0.029
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.972	0.028
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.973	0.027
I69 Sequelae of cerebrovascular disease	0.000	0.973	0.027
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.973	0.027
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.973	0.027
I62 Other nontraumatic intracranial haemorrhage	0.000	0.973	0.027
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.973	0.026
R40.0 Somnolence	0.026	0.974	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.974	0.026
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.974	0.026
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.975	0.025
I63.8 Other cerebral infarction	0.000	0.975	0.025
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.975	0.025
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.975	0.025
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.975	0.025
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.975	0.024
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.976	0.024
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.978	0.022
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.978	0.022
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.978	0.022
I69.3 Sequelae of cerebral infarction	0.000	0.979	0.021
R40 Somnolence, stupor and coma	0.021	0.979	0.000
I61 Intracerebral haemorrhage	0.000	0.979	0.021
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.979	0.021
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.979	0.021
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.980	0.020
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.980	0.020
R45.8 Other symptoms and signs involving emotional state	0.020	0.980	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.980	0.019
I62.1 Nontraumatic extradural haemorrhage	0.000	0.981	0.019
R45 Symptoms and signs involving emotional state	0.019	0.981	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.982	0.018
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.018	0.982	0.000
I60 Subarachnoid haemorrhage	0.000	0.983	0.017
R40.1 Stupor	0.015	0.985	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.985	0.015
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.985	0.015
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.985	0.015
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.985	0.015
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.985	0.015
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.985	0.015
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.985	0.015
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.985	0.015
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.985	0.015
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.985	0.015
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.985	0.015
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.985	0.015
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.985	0.015
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.985	0.015
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.985	0.015
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.985	0.015
I68.0 Cerebral amyloid angiopathy	0.000	0.985	0.015
R45.1 Restlessness and agitation	0.015	0.985	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.015	0.985	0.000
R40.2 Coma, unspecified	0.014	0.986	0.000
R45.0 Nervousness	0.014	0.986	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.986	0.014
R45.7 State of emotional shock and stress, unspecified	0.014	0.986	0.000
R45.6 Physical violence	0.014	0.986	0.000
R45.5 Hostility	0.014	0.986	0.000
R45.4 Irritability and anger	0.014	0.986	0.000
R45.3 Demoralisation and apathy	0.014	0.986	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.986	0.013
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.986	0.013
R41.3 Other amnesia	0.014	0.986	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.987	0.013
R45.2 Unhappiness	0.013	0.987	0.000
I67 Other cerebrovascular diseases	0.000	0.987	0.013
R46 Symptoms and signs involving appearance and behaviour	0.013	0.987	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.013	0.987	0.000
R43 Disturbances of smell and taste	0.013	0.987	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.987	0.013
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.013	0.987	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.988	0.012
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.988	0.012
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.988	0.012
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.988	0.012
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.988	0.012
R44.1 Visual hallucinations	0.012	0.988	0.000
R42 Dizziness and giddiness	0.012	0.988	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.989	0.011
R41.1 Anterograde amnesia	0.011	0.989	0.000
T40.2 Other opioids	0.011	0.989	0.000
T51.0 Ethanol	0.011	0.989	0.000
S02.30 Fracture of orbital floor (closed)	0.011	0.989	0.000
S02 Fracture of skull and facial bones	0.011	0.989	0.000
S02.3 Fracture of orbital floor	0.010	0.989	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.010	0.989	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.010	0.990	0.000
T51 Toxic effect of alcohol	0.010	0.990	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.990	0.010
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.990	0.010
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.990	0.010
I65.1 Occlusion and stenosis of basilar artery	0.000	0.990	0.010
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.990	0.010
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.990	0.010
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.010	0.990	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.990	0.010
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.990	0.010
I67.5 Moyamoya disease	0.000	0.990	0.010
I67.4 Hypertensive encephalopathy	0.000	0.990	0.010
I67.3 Progressive vascular leukoencephalopathy	0.000	0.990	0.010
E70-E90 Metabolic disorders	0.010	0.990	0.000
R44.2 Other hallucinations	0.010	0.990	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.010	0.990	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.010	0.990	0.000
R46.6 Undue concern and preoccupation with stressful events	0.010	0.990	0.000
R46.5 Suspiciousness and marked evasiveness	0.010	0.990	0.000
R46.4 Slowness and poor responsiveness	0.010	0.990	0.000
R46.3 Overactivity	0.010	0.990	0.000
R46.2 Strange and inexplicable behaviour	0.010	0.990	0.000
R46.1 Bizarre personal appearance	0.010	0.990	0.000
R46.0 Very low level of personal hygiene	0.010	0.990	0.000
R43.2 Parageusia	0.010	0.990	0.000
R43.1 Parosmia	0.010	0.990	0.000
R43.0 Anosmia	0.010	0.990	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.990	0.009
R43.8 Other and unspecified disturbances of smell and taste	0.009	0.990	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R44.0 Auditory hallucinations	0.009	0.990	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.009	0.991	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.009	0.991	0.000
T14 Injury of unspecified body region	0.009	0.991	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.009	0.991	0.000
R41.2 Retrograde amnesia	0.009	0.991	0.000
S00-S09 Injuries to the head	0.009	0.991	0.000
N13.3 Other and unspecified hydronephrosis	0.009	0.991	0.000
S05 Injury of eye and orbit	0.009	0.991	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.009	0.991	0.000
T14.0 Superficial injury of unspecified body region	0.009	0.991	0.000
S02.8 Fractures of other skull and facial bones	0.009	0.991	0.000
I67.2 Cerebral atherosclerosis	0.000	0.991	0.009
S02.4 Fracture of malar and maxillary bones	0.009	0.991	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.991	0.008
T21 Burn and corrosion of trunk	0.009	0.991	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.009	0.991	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.009	0.991	0.000
S02.7 Multiple fractures involving skull and facial bones	0.008	0.991	0.000
D73.0 Hyposplenism	0.000	0.992	0.008
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.008	0.992	0.000
C54.1 Endometrium	0.000	0.992	0.008
T47.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
T36 Poisoning by systemic antibiotics	0.008	0.992	0.000
S02.1 Fracture of base of skull	0.008	0.992	0.000
S90-S99 Injuries to the ankle and foot	0.008	0.992	0.000
T13 Other injuries of lower limb, level unspecified	0.008	0.992	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.008	0.992	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.992	0.008
T59 Toxic effect of other gases, fumes and vapours	0.008	0.992	0.000
T51.9 Alcohol, unspecified	0.008	0.992	0.000
S02.0 Fracture of vault of skull	0.008	0.992	0.000
S02.5 Fracture of tooth	0.008	0.992	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.008	0.992	0.000
T14.1 Open wound of unspecified body region	0.008	0.992	0.000
T40.6 Other and unspecified narcotics	0.008	0.992	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.008	0.992	0.000
S02.31 Fracture of orbital floor (open)	0.008	0.992	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.008	0.992	0.000
T40.8 Lysergide [LSD]	0.008	0.992	0.000
T40.7 Cannabis (derivatives)	0.008	0.992	0.000
T40.5 Cocaine	0.008	0.992	0.000
T40.3 Methadone	0.008	0.992	0.000
T40.1 Heroin	0.008	0.992	0.000
T40.0 Opium	0.008	0.992	0.000
E85 Amyloidosis	0.008	0.992	0.000
T39.0 Salicylates	0.008	0.992	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.992	0.008
S02.80 Fractures of other skull and facial bones (closed)	0.008	0.992	0.000
S05.9 Injury of eye and orbit, part unspecified	0.008	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.008	0.992	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.008	0.992	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.008	0.992	0.000
T51.8 Other alcohols	0.007	0.992	0.000
T51.3 Fusel oil	0.007	0.992	0.000
T51.2 2-Propanol	0.007	0.992	0.000
T51.1 Methanol	0.007	0.992	0.000
S02.2 Fracture of nasal bones	0.008	0.992	0.000
T40.4 Other synthetic narcotics	0.007	0.992	0.000
T59.9 Gases, fumes and vapours, unspecified	0.007	0.992	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.007	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.992	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.007	0.992	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.007	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
S02.6 Fracture of mandible	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
E84 Cystic fibrosis	0.007	0.993	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.007	0.993	0.000
E79 Disorders of purine and pyrimidine metabolism	0.007	0.993	0.000
E77 Disorders of glycoprotein metabolism	0.007	0.993	0.000
E76 Disorders of glycosaminoglycan metabolism	0.007	0.993	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.007	0.993	0.000
E72 Other disorders of amino-acid metabolism	0.007	0.993	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.007	0.993	0.000
E70 Disorders of aromatic amino-acid metabolism	0.007	0.993	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.007	0.993	0.000
S05.1 Contusion of eyeball and orbital tissues	0.007	0.993	0.000
S06 Intracranial injury	0.007	0.993	0.000
T21.3 Burn of third degree of trunk	0.007	0.993	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.993	0.007
T66-T78 Other and unspecified effects of external causes	0.007	0.993	0.000
D75.1 Secondary polycythaemia	0.000	0.993	0.007
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.007	0.993	0.000
T56 Toxic effect of metals	0.007	0.993	0.000
T65 Toxic effect of other and unspecified substances	0.007	0.993	0.000
T62 Toxic effect of other noxious substances eaten as food	0.007	0.993	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.007	0.993	0.000
T60 Toxic effect of pesticides	0.007	0.993	0.000
T57 Toxic effect of other inorganic substances	0.007	0.993	0.000
T54 Toxic effect of corrosive substances	0.007	0.993	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.007	0.993	0.000
T52 Toxic effect of organic solvents	0.007	0.993	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.007	0.993	0.000
T58 Toxic effect of carbon monoxide	0.007	0.993	0.000
T55 Toxic effect of soaps and detergents	0.007	0.993	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.007	0.993	0.000
T00-T07 Injuries involving multiple body regions	0.007	0.993	0.000
T21.0 Burn of unspecified degree of trunk	0.007	0.993	0.000
T21.2 Burn of second degree of trunk	0.007	0.993	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.007	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.993	0.007
D73 Diseases of spleen	0.000	0.993	0.007
E74 Other disorders of carbohydrate metabolism	0.007	0.993	0.000
T20 Burn and corrosion of head and neck	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.007	0.993	0.000
T09 Other injuries of spine and trunk, level unspecified	0.007	0.993	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.007	0.993	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.007	0.993	0.000
T12 Fracture of lower limb, level unspecified	0.007	0.993	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.007	0.993	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.007	0.993	0.000
T10 Fracture of upper limb, level unspecified	0.007	0.993	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.007	0.993	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.007	0.993	0.000
T08 Fracture of spine, level unspecified	0.007	0.993	0.000
T11 Other injuries of upper limb, level unspecified	0.007	0.993	0.000
T25 Burn and corrosion of ankle and foot	0.007	0.993	0.000
T23 Burn and corrosion of wrist and hand	0.007	0.993	0.000
T14.2 Fracture of unspecified body region	0.007	0.993	0.000
T14.9 Injury, unspecified	0.007	0.993	0.000
T14.8 Other injuries of unspecified body region	0.007	0.993	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.007	0.993	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.007	0.993	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.007	0.993	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.007	0.993	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.007	0.993	0.000
T36.0 Penicillins	0.007	0.993	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.007	0.993	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
T47.7 Emetics	0.007	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.007	0.993	0.000
T47.5 Digestants	0.007	0.993	0.000
T47.4 Other laxatives	0.007	0.993	0.000
T47.3 Saline and osmotic laxatives	0.007	0.993	0.000
T47.2 Stimulant laxatives	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.007	0.993	0.000
S08 Traumatic amputation of part of head	0.007	0.993	0.000
S07 Crushing injury of head	0.007	0.993	0.000
S04 Injury of cranial nerves	0.007	0.993	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.007	0.993	0.000
S99 Other and unspecified injuries of ankle and foot	0.007	0.993	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.007	0.993	0.000
S05.7 Avulsion of eye	0.007	0.993	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.007	0.993	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.007	0.993	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.007	0.993	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.007	0.993	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.007	0.993	0.000
R44.3 Hallucinations, unspecified	0.006	0.993	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.993	0.006
T33-T35 Frostbite	0.007	0.993	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.007	0.993	0.000
S02.10 Fracture of base of skull (closed)	0.007	0.993	0.000
S02.81 Fractures of other skull and facial bones (open)	0.006	0.993	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.006	0.993	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.006	0.993	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.006	0.993	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.993	0.000
T21.7 Corrosion of third degree of trunk	0.006	0.994	0.000
T21.6 Corrosion of second degree of trunk	0.006	0.994	0.000
T21.5 Corrosion of first degree of trunk	0.006	0.994	0.000
T21.4 Corrosion of unspecified degree of trunk	0.006	0.994	0.000
T21.1 Burn of first degree of trunk	0.006	0.994	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
E73 Lactose intolerance	0.006	0.994	0.000
T63 Toxic effect of contact with venomous animals	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
Z95.1 Presence of aortocoronary bypass graft	0.006	0.994	0.000
C80 Malignant neoplasm without specification of site	0.000	0.994	0.006
S02.71 Multiple fractures involving skull and facial bones (open)	0.006	0.994	0.000
T92 Sequelae of injuries of upper limb	0.006	0.994	0.000
E80.6 Other disorders of bilirubin metabolism	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T37.1 Antimycobacterial drugs	0.006	0.994	0.000
T37.0 Sulphonamides	0.006	0.994	0.000
D75.2 Essential thrombocytosis	0.000	0.994	0.006
T93 Sequelae of injuries of lower limb	0.006	0.994	0.000
E85.9 Amyloidosis, unspecified	0.006	0.994	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.006	0.994	0.000
S10-S19 Injuries to the neck	0.006	0.994	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
T36.8 Other systemic antibiotics	0.006	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
T36.6 Rifamycins	0.006	0.994	0.000
T36.5 Aminoglycosides	0.006	0.994	0.000
T36.4 Tetracyclines	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T36.2 Chloramphenicol group	0.006	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.994	0.000
S02.11 Fracture of base of skull (open)	0.006	0.994	0.000
S93.0 Dislocation of ankle joint	0.006	0.994	0.000
S98 Traumatic amputation of ankle and foot	0.006	0.994	0.000
S97 Crushing injury of ankle and foot	0.006	0.994	0.000
S95 Injury of blood vessels at ankle and foot level	0.006	0.994	0.000
S94 Injury of nerves at ankle and foot level	0.006	0.994	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.006	0.994	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.006	0.994	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.006	0.994	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.006	0.994	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.006	0.994	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.006	0.994	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.006	0.994	0.000
T13.1 Open wound of lower limb, level unspecified	0.006	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.3 Barbiturates	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
T42.1 Iminostilbenes	0.006	0.994	0.000
T42.0 Hydantoin derivatives	0.006	0.994	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
S02.00 Fracture of vault of skull (closed)	0.006	0.994	0.000
T59.7 Carbon dioxide	0.006	0.994	0.000
T59.6 Hydrogen sulphide	0.006	0.994	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.006	0.994	0.000
T59.4 Chlorine gas	0.006	0.994	0.000
T59.3 Lachrymogenic gas	0.006	0.994	0.000
T59.2 Formaldehyde	0.006	0.994	0.000
T59.1 Sulphur dioxide	0.006	0.994	0.000
T59.0 Nitrogen oxides	0.006	0.994	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.994	0.006
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.006	0.994	0.000
S50-S59 Injuries to the elbow and forearm	0.006	0.994	0.000
S02.50 Fracture of tooth (closed)	0.006	0.994	0.000
T79-T79 Certain early complications of trauma	0.006	0.994	0.000
G43.9 Migraine, unspecified	0.000	0.994	0.006
S06.3 Focal brain injury	0.006	0.994	0.000
S02.01 Fracture of vault of skull (open)	0.006	0.994	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
S91 Open wound of ankle and foot	0.006	0.994	0.000
S02.51 Fracture of tooth (open)	0.006	0.994	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.006	0.994	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.006	0.994	0.000
S06.2 Diffuse brain injury	0.006	0.994	0.000
S93.1 Dislocation of toe(s)	0.006	0.994	0.000
S92 Fracture of foot, except ankle	0.006	0.994	0.000
E85.8 Other amyloidosis	0.006	0.994	0.000
E85.4 Organ-limited amyloidosis	0.006	0.994	0.000
E85.3 Secondary systemic amyloidosis	0.006	0.994	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.006	0.994	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.006	0.994	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.006	0.994	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.006	0.994	0.000
S70-S79 Injuries to the hip and thigh	0.006	0.994	0.000
T02 Fractures involving multiple body regions	0.006	0.994	0.000
S06.4 Epidural haemorrhage	0.006	0.994	0.000
T98 Sequelae of other and unspecified effects of external causes	0.006	0.994	0.000
E88 Other metabolic disorders	0.006	0.994	0.000
S05.8 Other injuries of eye and orbit	0.006	0.994	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
S99.9 Unspecified injury of ankle and foot	0.006	0.994	0.000
S90 Superficial injury of ankle and foot	0.006	0.994	0.000
S02.21 Fracture of nasal bones (open)	0.006	0.994	0.000
T78 Adverse effects, not elsewhere classified	0.006	0.994	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.994	0.006
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
T70 Effects of air pressure and water pressure	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.994	0.000
T46.7 Peripheral vasodilators	0.005	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.994	0.000
T46.1 Calcium-channel blockers	0.005	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.994	0.000
N13 Obstructive and reflux uropathy	0.006	0.994	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.994	0.006
S93.4 Sprain and strain of ankle	0.006	0.994	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.006	0.994	0.000
S93.5 Sprain and strain of toe(s)	0.006	0.994	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.006	0.994	0.000
T42.4 Benzodiazepines	0.006	0.994	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.006	0.994	0.000
T95 Sequelae of burns, corrosions and frostbite	0.006	0.994	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.006	0.994	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.006	0.994	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.006	0.994	0.000
D73.5 Infarction of spleen	0.000	0.994	0.006
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.994	0.006
T50.8 Diagnostic agents	0.005	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.994	0.000
T50.5 Appetite depressants	0.005	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.005	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.994	0.000
S02.61 Fracture of mandible (open)	0.005	0.994	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.006	0.994	0.000
T90 Sequelae of injuries of head	0.006	0.994	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.005	0.994	0.000
E80.5 Crigler-Najjar syndrome	0.005	0.994	0.000
E80.3 Defects of catalase and peroxydase	0.005	0.994	0.000
E80.2 Other porphyria	0.005	0.994	0.000
E80.1 Porphyria cutanea tarda	0.005	0.994	0.000
E80.0 Hereditary erythropoietic porphyria	0.005	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.994	0.000
T45.5 Anticoagulants	0.005	0.994	0.000
T45.4 Iron and its compounds	0.005	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations