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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11837432
log Bayes Factor = 16.9657
Chromosome 12   position 2,170,893  (GRCh37) Explore rs11837432 on Ensembl!
Variant rs11837432 is part of Cluster X0247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
J30-J39 Other diseases of upper respiratory tract
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
S80-S89 Injuries to the knee and lower leg
0.996 0.004 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
J34 Other disorders of nose and nasal sinuses
0.988 0.012 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.988 0.012 0.000
H30-H36 Disorders of choroid and retina
0.987 0.013 0.000
E11 Non-insulin-dependent diabetes mellitus
0.985 0.015 0.000
S82 Fracture of lower leg, including ankle
0.984 0.016 0.000
Chapter VIII Diseases of the ear and mastoid process
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.974 0.026 0.000
E11.9 Without complications
0.968 0.032 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.966 0.034 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.961 0.039 0.000
H65-H75 Diseases of middle ear and mastoid
0.961 0.039 0.000
S60-S69 Injuries to the wrist and hand
0.960 0.040 0.000
H35 Other retinal disorders
0.955 0.045 0.000
B35-B49 Mycoses
0.953 0.047 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.946 0.054 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.945 0.055 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.945 0.055 0.000
E10 Insulin-dependent diabetes mellitus
0.945 0.055 0.000
S62 Fracture at wrist and hand level
0.941 0.059 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.930 0.070 0.000
E65-E68 Obesity and other hyperalimentation
0.929 0.071 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.929 0.071 0.000
H25-H28 Disorders of lens
0.923 0.077 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.923 0.077 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.922 0.078 0.000
S82.6 Fracture of lateral malleolus
0.921 0.079 0.000
J34.3 Hypertrophy of nasal turbinates
0.920 0.080 0.000
H55-H59 Other disorders of eye and adnexa
0.919 0.081 0.000
R26 Abnormalities of gait and mobility
0.917 0.083 0.000
E14 Unspecified diabetes mellitus
0.916 0.084 0.000
H35.3 Degeneration of macula and posterior pole
0.913 0.087 0.000
M05-M14 Inflammatory polyarthropathies
0.907 0.093 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.905 0.095 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.904 0.096 0.000
T92 Sequelae of injuries of upper limb
0.902 0.098 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.899 0.101 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.897 0.103 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.896 0.104 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.892 0.108 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.891 0.109 0.000
M45-M49 Spondylopathies
0.888 0.112 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.882 0.118 0.000
H25 Senile cataract
0.880 0.120 0.000
S62.6 Fracture of other finger
0.879 0.121 0.000
S82.60 Fracture of lateral malleolus (closed)
0.877 0.123 0.000
S89 Other and unspecified injuries of lower leg
0.876 0.124 0.000
J30 Vasomotor and allergic rhinitis
0.874 0.126 0.000
H53-H54 Visual disturbances and blindness
0.872 0.128 0.000
E66 Obesity
0.872 0.128 0.000
J20-J22 Other acute lower respiratory infections
0.872 0.128 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.870 0.130 0.000
Chapter VI Diseases of the nervous system
0.869 0.131 0.000
B37 Candidiasis
0.868 0.132 0.000
Y83.6 Removal of other organ (partial) (total)
0.867 0.133 0.000
H10-H13 Disorders of conjunctiva
0.866 0.134 0.000
J32 Chronic sinusitis
0.866 0.134 0.000
S80 Superficial injury of lower leg
0.866 0.134 0.000
M86-M90 Other osteopathies
0.865 0.135 0.000
H66 Suppurative and unspecified otitis media
0.864 0.136 0.000
E10.3 With ophthalmic complications
0.859 0.141 0.000
J34.2 Deviated nasal septum
0.857 0.143 0.000
S82.5 Fracture of medial malleolus
0.853 0.147 0.000
D80-D89 Certain disorders involving the immune mechanism
0.852 0.148 0.000
M10 Gout
0.849 0.151 0.000
D70 Agranulocytosis
0.848 0.152 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.848 0.152 0.000
H72 Perforation of tympanic membrane
0.846 0.154 0.000
S82.3 Fracture of lower end of tibia
0.845 0.155 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.838 0.162 0.000
S50-S59 Injuries to the elbow and forearm
0.838 0.162 0.000
E16 Other disorders of pancreatic internal secretion
0.838 0.162 0.000
R23 Other skin changes
0.837 0.163 0.000
J95-J99 Other diseases of the respiratory system
0.837 0.163 0.000
H36 Retinal disorders in diseases classified elsewhere
0.835 0.165 0.000
H71 Cholesteatoma of middle ear
0.834 0.166 0.000
J31.0 Chronic rhinitis
0.834 0.166 0.000
R47-R49 Symptoms and signs involving speech and voice
0.833 0.167 0.000
M48 Other spondylopathies
0.831 0.169 0.000
H50 Other strabismus
0.830 0.170 0.000
R25 Abnormal involuntary movements
0.825 0.175 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.824 0.176 0.000
T81 Complications of procedures, not elsewhere classified
0.823 0.177 0.000
S62.3 Fracture of other metacarpal bone
0.822 0.178 0.000
T91 Sequelae of injuries of neck and trunk
0.820 0.180 0.000
D60-D64 Aplastic and other anaemias
0.820 0.180 0.000
X60-X84 Intentional self-harm
0.819 0.181 0.000
R20 Disturbances of skin sensation
0.819 0.181 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.818 0.182 0.000
E10.9 Without complications
0.814 0.186 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.812 0.188 0.000
Chapter II Neoplasms
0.811 0.189 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.810 0.190 0.000
H55 Nystagmus and other irregular eye movements
0.810 0.190 0.000
H25.0 Senile incipient cataract
0.810 0.190 0.000
S20-S29 Injuries to the thorax
0.808 0.192 0.000
E14.3 With ophthalmic complications
0.808 0.192 0.000
H34 Retinal vascular occlusions
0.808 0.192 0.000
M40-M43 Deforming dorsopathies
0.807 0.193 0.000
M10.9 Gout, unspecified
0.807 0.193 0.000
H80-H83 Diseases of inner ear
0.804 0.196 0.000
S82.1 Fracture of upper end of tibia
0.803 0.197 0.000
S82.4 Fracture of fibula alone
0.801 0.199 0.000
E66.9 Obesity, unspecified
0.798 0.202 0.000
H35.8 Other specified retinal disorders
0.798 0.202 0.000
J35 Chronic diseases of tonsils and adenoids
0.795 0.205 0.000
C50-C50 Malignant neoplasm of breast
0.793 0.207 0.000
J09-J18 Influenza and pneumonia
0.793 0.207 0.000
B49 Unspecified mycosis
0.791 0.209 0.000
E16.2 Hypoglycaemia, unspecified
0.790 0.210 0.000
J31.2 Chronic pharyngitis
0.789 0.211 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.789 0.211 0.000
R27 Other lack of coordination
0.788 0.211 0.000
B15-B19 Viral hepatitis
0.788 0.212 0.000
M13 Other arthritis
0.788 0.212 0.000
J40-J47 Chronic lower respiratory diseases
0.787 0.213 0.000
H27 Other disorders of lens
0.786 0.214 0.000
E20-E35 Disorders of other endocrine glands
0.784 0.216 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.782 0.218 0.000
B99-B99 Other infectious diseases
0.782 0.218 0.000
H25.1 Senile nuclear cataract
0.780 0.220 0.000
C50 Malignant neoplasm of breast
0.780 0.220 0.000
E50-E64 Other nutritional deficiencies
0.779 0.221 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.779 0.221 0.000
H18 Other disorders of cornea
0.778 0.222 0.000
M48.0 Spinal stenosis
0.777 0.223 0.000
Chapter XXII Codes for special purposes
0.777 0.223 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.777 0.223 0.000
E11.3 With ophthalmic complications
0.776 0.224 0.000
S62.61 Fracture of other finger (open)
0.775 0.225 0.000
J22 Unspecified acute lower respiratory infection
0.773 0.227 0.000
E14.9 Without complications
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
T90 Sequelae of injuries of head
0.771 0.229 0.000
W00-W19 Falls
0.771 0.229 0.000
S62.60 Fracture of other finger (closed)
0.771 0.229 0.000
B37.9 Candidiasis, unspecified
0.770 0.230 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.770 0.230 0.000
A80-A89 Viral infections of the central nervous system
0.770 0.230 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.769 0.230 0.000
H50.1 Divergent concomitant strabismus
0.768 0.232 0.000
D86 Sarcoidosis
0.768 0.232 0.000
H69 Other disorders of Eustachian tube
0.767 0.233 0.000
J32.0 Chronic maxillary sinusitis
0.765 0.235 0.000
S80.8 Other superficial injuries of lower leg
0.765 0.235 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.764 0.236 0.000
G82 Paraplegia and tetraplegia
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.764 0.236 0.000
V40-V49 Car occupant injured in transport accident
0.764 0.236 0.000
H74 Other disorders of middle ear and mastoid
0.763 0.237 0.000
M20-M25 Other joint disorders
0.762 0.238 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.762 0.238 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.761 0.239 0.000
H11 Other disorders of conjunctiva
0.760 0.240 0.000
S82.50 Fracture of medial malleolus (closed)
0.760 0.240 0.000
R49 Voice disturbances
0.759 0.241 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.759 0.241 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.758 0.242 0.000
D61 Other aplastic anaemias
0.757 0.243 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.756 0.244 0.000
E11.6 With other specified complications
0.756 0.244 0.000
C51-C58 Malignant neoplasms of female genital organs
0.756 0.244 0.000
T86 Failure and rejection of transplanted organs and tissues
0.755 0.245 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.755 0.245 0.000
M80-M85 Disorders of bone density and structure
0.752 0.248 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.752 0.248 0.000
J30.1 Allergic rhinitis due to pollen
0.750 0.250 0.000
S62.5 Fracture of thumb
0.750 0.250 0.000
H33 Retinal detachments and breaks
0.749 0.251 0.000
B44 Aspergillosis
0.748 0.252 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.748 0.252 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.747 0.253 0.000
S82.30 Fracture of lower end of tibia (closed)
0.745 0.255 0.000
H66.3 Other chronic suppurative otitis media
0.744 0.256 0.000
G90-G99 Other disorders of the nervous system
0.743 0.257 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.743 0.257 0.000
H53 Visual disturbances
0.743 0.257 0.000
B37.0 Candidal stomatitis
0.742 0.258 0.000
J38.2 Nodules of vocal cords
0.742 0.258 0.000
E10.2 With renal complications
0.740 0.260 0.000
H35.5 Hereditary retinal dystrophy
0.740 0.260 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.739 0.261 0.000
E10.4 With neurological complications
0.738 0.262 0.000
B65-B83 Helminthiases
0.738 0.262 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.738 0.262 0.000
H16 Keratitis
0.737 0.263 0.000
E11.4 With neurological complications
0.737 0.263 0.000
E66.8 Other obesity
0.737 0.263 0.000
C50.4 Upper-outer quadrant of breast
0.736 0.264 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.736 0.264 0.000
S67 Crushing injury of wrist and hand
0.736 0.264 0.000
M45 Ankylosing spondylitis
0.735 0.265 0.000
H35.0 Background retinopathy and retinal vascular changes
0.734 0.265 0.000
S89.9 Unspecified injury of lower leg
0.734 0.266 0.000
S82.0 Fracture of patella
0.733 0.266 0.000
H72.2 Other marginal perforations of tympanic membrane
0.730 0.270 0.000
M10.99 Gout, unspecified (Site unspecified)
0.729 0.271 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.729 0.271 0.000
M25 Other joint disorders, not elsewhere classified
0.729 0.271 0.000
M24 Other specific joint derangements
0.729 0.271 0.000
J37 Chronic laryngitis and laryngotracheitis
0.728 0.272 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.728 0.272 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.726 0.274 0.000
M89 Other disorders of bone
0.726 0.274 0.000
H36.0 Diabetic retinopathy
0.726 0.274 0.000
S89.8 Other specified injuries of lower leg
0.724 0.275 0.000
R25.1 Tremor, unspecified
0.724 0.276 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.724 0.276 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.723 0.276 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.723 0.277 0.000
H66.9 Otitis media, unspecified
0.723 0.277 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.722 0.278 0.000
B35 Dermatophytosis
0.720 0.280 0.000
Y40 Systemic antibiotics
0.720 0.280 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.719 0.281 0.000
J98 Other respiratory disorders
0.719 0.281 0.000
E11.5 With peripheral circulatory complications
0.719 0.281 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.717 0.283 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.717 0.283 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.717 0.283 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
Y83.8 Other surgical procedures
0.715 0.285 0.000
M11 Other crystal arthropathies
0.714 0.286 0.000
H57 Other disorders of eye and adnexa
0.714 0.286 0.000
S88 Traumatic amputation of lower leg
0.714 0.286 0.000
S87 Crushing injury of lower leg
0.714 0.286 0.000
S86 Injury of muscle and tendon at lower leg level
0.714 0.286 0.000
S85 Injury of blood vessels at lower leg level
0.714 0.286 0.000
S84 Injury of nerves at lower leg level
0.714 0.286 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.714 0.286 0.000
S51 Open wound of forearm
0.713 0.287 0.000
D61.9 Aplastic anaemia, unspecified
0.712 0.288 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.289 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.711 0.289 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.290 0.000
Y10-Y34 Event of undetermined intent
0.709 0.290 0.000
Y00-Y09 Assault
0.709 0.290 0.000
X85-X99 Assault
0.709 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.290 0.000
X50-X57 Overexertion, travel and privation
0.709 0.290 0.000
X30-X39 Exposure to forces of nature
0.709 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.290 0.000
X10-X19 Contact with heat and hot substances
0.709 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.290 0.000
W75-W84 Other accidental threats to breathing
0.709 0.290 0.000
W65-W74 Accidental drowning and submersion
0.709 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.290 0.000
V95-V97 Air and space transport accidents
0.709 0.290 0.000
V90-V94 Water transport accidents
0.709 0.290 0.000
V80-V89 Other land transport accidents
0.709 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.290 0.000
Y57 Other and unspecified drugs and medicaments
0.710 0.290 0.000
Q60-Q64 Congenital malformations of the urinary system
0.709 0.291 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.709 0.291 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.709 0.291 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.708 0.291 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.708 0.291 0.000
H50.9 Strabismus, unspecified
0.708 0.292 0.000
S50 Superficial injury of forearm
0.708 0.292 0.000
M25.7 Osteophyte
0.708 0.292 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.707 0.293 0.000
H31 Other disorders of choroid
0.707 0.293 0.000
H30 Chorioretinal inflammation
0.707 0.293 0.000
E11.8 With unspecified complications
0.706 0.294 0.000
E11.7 With multiple complications
0.706 0.294 0.000
E11.1 With ketoacidosis
0.706 0.294 0.000
E11.0 With coma
0.706 0.294 0.000
R49.0 Dysphonia
0.706 0.294 0.000
M48.06 Spinal stenosis (Lumbar region)
0.706 0.294 0.000
S82.9 Fracture of lower leg, part unspecified
0.705 0.295 0.000
S82.7 Multiple fractures of lower leg
0.705 0.295 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.703 0.296 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.703 0.297 0.000
W20-W49 Exposure to inanimate mechanical forces
0.701 0.299 0.000
R22.1 Localised swelling, mass and lump, neck
0.701 0.299 0.000
H73 Other disorders of tympanic membrane
0.701 0.299 0.000
B37.4 Candidiasis of other urogenital sites
0.700 0.300 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.699 0.301 0.000
G82.2 Paraplegia, unspecified
0.699 0.301 0.000
H25.9 Senile cataract, unspecified
0.699 0.301 0.000
M00-M03 Infectious arthropathies
0.698 0.301 0.000
H54 Blindness and low vision
0.698 0.302 0.000
M91-M94 Chondropathies
0.697 0.302 0.000
E13 Other specified diabetes mellitus
0.697 0.303 0.000
E65 Localised adiposity
0.696 0.304 0.000
J00-J06 Acute upper respiratory infections
0.696 0.304 0.000
R23.8 Other and unspecified skin changes
0.696 0.304 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
Y84.6 Urinary catheterisation
0.694 0.305 0.000
J30.3 Other allergic rhinitis
0.694 0.306 0.000
T91.3 Sequelae of injury of spinal cord
0.693 0.307 0.000
D55-D59 Haemolytic anaemias
0.693 0.307 0.000
E55 Vitamin D deficiency
0.693 0.307 0.000
Y84.2 Radiological procedure and radiotherapy
0.692 0.308 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.691 0.309 0.000
H18.8 Other specified disorders of cornea
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.691 0.309 0.000
T98 Sequelae of other and unspecified effects of external causes
0.689 0.311 0.000
T95 Sequelae of burns, corrosions and frostbite
0.689 0.311 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.689 0.311 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.689 0.311 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.689 0.311 0.000
H70 Mastoiditis and related conditions
0.689 0.311 0.000
H68 Eustachian salpingitis and obstruction
0.689 0.311 0.000
H67 Otitis media in diseases classified elsewhere
0.689 0.311 0.000
S65 Injury of blood vessels at wrist and hand level
0.688 0.312 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.688 0.312 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.688 0.312 0.000
M25.77 Osteophyte (Ankle and foot)
0.688 0.312 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.688 0.312 0.000
T66-T78 Other and unspecified effects of external causes
0.688 0.312 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.688 0.312 0.000
H35.6 Retinal haemorrhage
0.687 0.313 0.000
M90 Osteopathies in diseases classified elsewhere
0.687 0.313 0.000
H60-H62 Diseases of external ear
0.687 0.313 0.000
J44 Other chronic obstructive pulmonary disease
0.686 0.314 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.686 0.314 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.685 0.315 0.000
H35.9 Retinal disorder, unspecified
0.684 0.315 0.000
H35.7 Separation of retinal layers
0.684 0.315 0.000
H35.2 Other proliferative retinopathy
0.684 0.315 0.000
H35.1 Retinopathy of prematurity
0.684 0.315 0.000
M13.9 Arthritis, unspecified
0.684 0.316 0.000
R22.0 Localised swelling, mass and lump, head
0.684 0.316 0.000
B48 Other mycoses, not elsewhere classified
0.683 0.317 0.000
B47 Mycetoma
0.683 0.317 0.000
B46 Zygomycosis
0.683 0.317 0.000
B45 Cryptococcosis
0.683 0.317 0.000
B43 Chromomycosis and phaeomycotic abscess
0.683 0.317 0.000
B42 Sporotrichosis
0.683 0.317 0.000
B41 Paracoccidioidomycosis
0.683 0.317 0.000
B40 Blastomycosis
0.683 0.317 0.000
B39 Histoplasmosis
0.683 0.317 0.000
B38 Coccidioidomycosis
0.683 0.317 0.000
B36 Other superficial mycoses
0.683 0.317 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.683 0.317 0.000
S81 Open wound of lower leg
0.683 0.317 0.000
G83 Other paralytic syndromes
0.682 0.318 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.682 0.318 0.000
S61 Open wound of wrist and hand
0.682 0.318 0.000
T92.0 Sequelae of open wound of upper limb
0.682 0.318 0.000
T79-T79 Certain early complications of trauma
0.681 0.319 0.000
R27.0 Ataxia, unspecified
0.681 0.319 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.680 0.320 0.000
H34.8 Other retinal vascular occlusions
0.680 0.320 0.000
R23.4 Changes in skin texture
0.679 0.321 0.000
E11.2 With renal complications
0.678 0.321 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.678 0.322 0.000
D86.9 Sarcoidosis, unspecified
0.678 0.322 0.000
E10.8 With unspecified complications
0.677 0.323 0.000
E10.7 With multiple complications
0.677 0.323 0.000
E10.6 With other specified complications
0.677 0.323 0.000
E10.5 With peripheral circulatory complications
0.677 0.323 0.000
E10.0 With coma
0.677 0.323 0.000
Y52 Agents primarily affecting the cardiovascular system
0.677 0.323 0.000
G20-G26 Extrapyramidal and movement disorders
0.677 0.323 0.000
W13 Fall from, out of or through building or structure
0.676 0.324 0.000
S62.7 Multiple fractures of fingers
0.675 0.325 0.000
S62.4 Multiple fractures of metacarpal bones
0.675 0.325 0.000
S62.2 Fracture of first metacarpal bone
0.675 0.325 0.000
S62.1 Fracture of other carpal bone(s)
0.675 0.325 0.000
H21 Other disorders of iris and ciliary body
0.675 0.325 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.675 0.325 0.000
E40-E46 Malnutrition
0.675 0.325 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.675 0.325 0.000
S82.2 Fracture of shaft of tibia
0.674 0.326 0.000
Q00-Q07 Congenital malformations of the nervous system
0.673 0.326 0.000
S82.10 Fracture of upper end of tibia (closed)
0.673 0.327 0.000
Y83.9 Surgical procedure, unspecified
0.673 0.327 0.000
H49 Paralytic strabismus
0.672 0.328 0.000
C53 Malignant neoplasm of cervix uteri
0.671 0.329 0.000
C50.2 Upper-inner quadrant of breast
0.671 0.329 0.000
S68 Traumatic amputation of wrist and hand
0.670 0.329 0.000
R22.2 Localised swelling, mass and lump, trunk
0.670 0.330 0.000
S82.40 Fracture of fibula alone (closed)
0.670 0.330 0.000
J33 Nasal polyp
0.668 0.332 0.000
T87 Complications peculiar to reattachment and amputation
0.667 0.333 0.000
E67 Other hyperalimentation
0.666 0.334 0.000
E68 Sequelae of hyperalimentation
0.666 0.334 0.000
J31.1 Chronic nasopharyngitis
0.666 0.334 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.666 0.334 0.000
S69 Other and unspecified injuries of wrist and hand
0.663 0.337 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.662 0.338 0.000
R20.2 Paraesthesia of skin
0.662 0.338 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.661 0.339 0.000
H83 Other diseases of inner ear
0.661 0.339 0.000
H33.3 Retinal breaks without detachment
0.661 0.339 0.000
H90-H95 Other disorders of ear
0.661 0.339 0.000
S82.61 Fracture of lateral malleolus (open)
0.660 0.339 0.000
M07 Psoriatic and enteropathic arthropathies
0.660 0.340 0.000
M24.0 Loose body in joint
0.659 0.340 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.659 0.341 0.000
J98.4 Other disorders of lung
0.658 0.342 0.000
S27 Injury of other and unspecified intrathoracic organs
0.658 0.342 0.000
R26.1 Paralytic gait
0.657 0.343 0.000
R26.0 Ataxic gait
0.657 0.343 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.657 0.343 0.000
J38.4 Oedema of larynx
0.657 0.343 0.000
E14.8 With unspecified complications
0.656 0.343 0.000
E14.7 With multiple complications
0.656 0.343 0.000
E14.6 With other specified complications
0.656 0.343 0.000
E14.5 With peripheral circulatory complications
0.656 0.343 0.000
E14.4 With neurological complications
0.656 0.343 0.000
E14.2 Withrenal complications
0.656 0.343 0.000
E14.1 With ketoacidosis
0.656 0.343 0.000
E14.0 With coma
0.656 0.343 0.000
M41 Scoliosis
0.656 0.344 0.000
J32.8 Other chronic sinusitis
0.656 0.344 0.000
M87 Osteonecrosis
0.655 0.345 0.000
Y43 Primarily systemic agents
0.655 0.345 0.000
R23.1 Pallor
0.654 0.346 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.654 0.346 0.000
J38.0 Paralysis of vocal cords and larynx
0.654 0.346 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.654 0.346 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.653 0.347 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.652 0.348 0.000
H72.0 Central perforation of tympanic membrane
0.651 0.349 0.000
M84 Disorders of continuity of bone
0.651 0.349 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.651 0.349 0.000
J35.2 Hypertrophy of adenoids
0.651 0.349 0.000
M14 Arthropathies in other diseases classified elsewhere
0.650 0.350 0.000
M12 Other specific arthropathies
0.650 0.350 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.650 0.350 0.000
M08 Juvenile arthritis
0.650 0.350 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.650 0.350 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.649 0.351 0.000
E15 Nondiabetic hypoglycaemic coma
0.649 0.351 0.000
C50.8 Overlapping lesion of breast
0.649 0.351 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.648 0.352 0.000
Q80-Q89 Other congenital malformations
0.648 0.352 0.000
Q35-Q37 Cleft lip and cleft palate
0.648 0.352 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.648 0.352 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.648 0.352 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.647 0.353 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.647 0.353 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.647 0.353 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.647 0.353 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.647 0.353 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.647 0.353 0.000
D75 Other diseases of blood and blood-forming organs
0.646 0.353 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.646 0.354 0.000
H10 Conjunctivitis
0.645 0.355 0.000
S90-S99 Injuries to the ankle and foot
0.645 0.355 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.645 0.355 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.644 0.355 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.644 0.355 0.000
H17 Corneal scars and opacities
0.644 0.355 0.000
H15 Disorders of sclera
0.644 0.355 0.000
C54 Malignant neoplasm of corpus uteri
0.644 0.356 0.000
J20 Acute bronchitis
0.644 0.356 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.644 0.356 0.000
S60 Superficial injury of wrist and hand
0.644 0.356 0.000
S29 Other and unspecified injuries of thorax
0.644 0.356 0.000
S40-S49 Injuries to the shoulder and upper arm
0.643 0.356 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.643 0.357 0.000
J38.3 Other diseases of vocal cords
0.643 0.357 0.000
H51 Other disorders of binocular movement
0.642 0.358 0.000
H33.4 Traction detachment of retina
0.642 0.358 0.000
V20-V29 Motorcycle rider injured in transport accident
0.642 0.358 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
J32.9 Chronic sinusitis, unspecified
0.641 0.359 0.000
J36 Peritonsillar abscess
0.641 0.359 0.000
R23.3 Spontaneous ecchymoses
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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