TreeWAS – Variant ID: rs1187256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.988	0.012	0.000
K57 Diverticular disease of intestine	0.061	0.939	0.000
D38.1 Trachea, bronchus and lung	0.059	0.941	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.057	0.943	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.053	0.947	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.051	0.949	0.000
D41.4 Bladder	0.051	0.949	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.050	0.950	0.000
D38.0 Larynx	0.049	0.951	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.049	0.951	0.000
D39.1 Ovary	0.047	0.953	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.047	0.953	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.044	0.955	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.042	0.958	0.000
D37.7 Other digestive organs	0.042	0.958	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.041	0.958	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.041	0.958	0.000
D37.9 Digestive organ, unspecified	0.041	0.959	0.000
D38.6 Respiratory organ, unspecified	0.041	0.959	0.000
D38.5 Other respiratory organs	0.041	0.959	0.000
D38.4 Thymus	0.041	0.959	0.000
D38.3 Mediastinum	0.041	0.959	0.000
D38.2 Pleura	0.041	0.959	0.000
D46 Myelodysplastic syndromes	0.041	0.959	0.000
D37.3 Appendix	0.040	0.960	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.039	0.961	0.000
D39.0 Uterus	0.038	0.961	0.000
D37.1 Stomach	0.038	0.961	0.000
D37.5 Rectum	0.038	0.962	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.038	0.962	0.000
D45 Polycythaemia vera	0.038	0.962	0.000
D41.9 Urinary organ, unspecified	0.037	0.963	0.000
D41.7 Other urinary organs	0.037	0.963	0.000
D41.3 Urethra	0.037	0.963	0.000
D41.2 Ureter	0.037	0.963	0.000
D41.1 Renal pelvis	0.037	0.963	0.000
D37.6 Liver, gallbladder and bile ducts	0.036	0.964	0.000
D39.9 Female genital organ, unspecified	0.036	0.964	0.000
D39.7 Other female genital organs	0.036	0.964	0.000
D39.2 Placenta	0.036	0.964	0.000
D41.0 Kidney	0.035	0.965	0.000
D37.2 Small intestine	0.035	0.965	0.000
D43.0 Brain, supratentorial	0.033	0.967	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.032	0.967	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.032	0.968	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.032	0.968	0.000
D43.2 Brain, unspecified	0.032	0.968	0.000
D37.4 Colon	0.031	0.969	0.000
D43.9 Central nervous system, unspecified	0.030	0.970	0.000
D43.7 Other parts of central nervous system	0.030	0.970	0.000
D43.4 Spinal cord	0.030	0.970	0.000
D43.3 Cranial nerves	0.030	0.970	0.000
D43.1 Brain, infratentorial	0.030	0.970	0.000
D46.7 Other myelodysplastic syndromes	0.029	0.971	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.029	0.971	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.029	0.971	0.000
D46.4 Refractory anaemia, unspecified	0.029	0.971	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.029	0.971	0.000
D46.1 Refractory anaemia with sideroblasts	0.029	0.971	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.029	0.971	0.000
D44.8 Pluriglandular involvement	0.029	0.971	0.000
D46.2 Refractory anaemia with excess of blasts	0.029	0.971	0.000
D44.4 Craniopharyngeal duct	0.029	0.971	0.000
D44.1 Adrenal gland	0.028	0.971	0.000
D44.9 Endocrine gland, unspecified	0.028	0.972	0.000
D44.7 Aortic body and other paraganglia	0.028	0.972	0.000
D44.6 Carotid body	0.028	0.972	0.000
D44.5 Pineal gland	0.028	0.972	0.000
D44.2 Parathyroid gland	0.028	0.972	0.000
D44.0 Thyroid gland	0.028	0.972	0.000
D42.9 Meninges, unspecified	0.027	0.972	0.000
D42.1 Spinal meninges	0.027	0.972	0.000
D42.0 Cerebral meninges	0.027	0.972	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.026	0.974	0.000
D44.3 Pituitary gland	0.025	0.975	0.000
D37.0 Lip, oral cavity and pharynx	0.025	0.975	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.976	0.024
D40.9 Male genital organ, unspecified	0.023	0.977	0.000
D40.7 Other male genital organs	0.023	0.977	0.000
D40.0 Prostate	0.021	0.979	0.000
D40.1 Testis	0.021	0.979	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.020	0.980	0.000
N81.1 Cystocele	0.018	0.982	0.000
N81.6 Rectocele	0.018	0.982	0.000
D48.0 Bone and articular cartilage	0.017	0.983	0.000
I71 Aortic aneurysm and dissection	0.000	0.985	0.015
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.014	0.985	0.000
D48.4 Peritoneum	0.014	0.985	0.000
D48.3 Retroperitoneum	0.014	0.985	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.014	0.985	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.986	0.014
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.013	0.986	0.000
N81 Female genital prolapse	0.013	0.987	0.000
N81.9 Female genital prolapse, unspecified	0.013	0.987	0.000
D48.5 Skin	0.012	0.988	0.000
D48.7 Other specified sites	0.012	0.988	0.000
D75.1 Secondary polycythaemia	0.012	0.988	0.000
I71.0 Dissection of aorta [any part]	0.000	0.988	0.011
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.989	0.011
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.989	0.011
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.989	0.011
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.989	0.011
Y43.3 Other antineoplastic drugs	0.011	0.989	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.990	0.010
D70 Agranulocytosis	0.010	0.990	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.990	0.010
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.010	0.990	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.010	0.990	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.010	0.990	0.000
D47.4 Osteomyelofibrosis	0.010	0.990	0.000
D48.6 Breast	0.010	0.990	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.009	0.990	0.000
N81.0 Female urethrocele	0.009	0.990	0.000
N81.4 Uterovaginal prolapse, unspecified	0.009	0.991	0.000
D75 Other diseases of blood and blood-forming organs	0.009	0.991	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.008	0.992	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.007	0.993	0.000
E10.9 Without complications	0.007	0.993	0.000
E10 Insulin-dependent diabetes mellitus	0.007	0.993	0.000
D47.2 Monoclonal gammopathy	0.007	0.993	0.000
D75.0 Familial erythrocytosis	0.007	0.993	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.007	0.993	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.993	0.007
N81.5 Vaginal enterocele	0.007	0.993	0.000
D48.1 Connective and other soft tissue	0.006	0.993	0.001
E10.4 With neurological complications	0.007	0.993	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.006	0.994	0.000
E10.3 With ophthalmic complications	0.006	0.994	0.000
S32.10 Fracture of sacrum (closed)	0.006	0.994	0.000
N81.8 Other female genital prolapse	0.006	0.994	0.000
S32 Fracture of lumbar spine and pelvis	0.006	0.994	0.000
B34.9 Viral infection, unspecified	0.006	0.994	0.000
S32.1 Fracture of sacrum	0.006	0.994	0.000
D74 Methaemoglobinaemia	0.006	0.994	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.006	0.994	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.006	0.994	0.000
S32.5 Fracture of pubis	0.006	0.994	0.000
S32.50 Fracture of pubis (closed)	0.006	0.994	0.000
E10.6 With other specified complications	0.006	0.994	0.000
N73.6 Female pelvic peritoneal adhesions	0.000	0.994	0.006
Z36.9 Antenatal screening, unspecified	0.000	0.994	0.006
Z73.9 Problem related to life-management difficulty, unspecified	0.006	0.994	0.000
S32.3 Fracture of ilium	0.006	0.994	0.000
Y43 Primarily systemic agents	0.006	0.994	0.000
D47.1 Chronic myeloproliferative disease	0.005	0.994	0.001
D73 Diseases of spleen	0.006	0.994	0.000
E10.2 With renal complications	0.006	0.994	0.000
S32.0 Fracture of lumbar vertebra	0.006	0.994	0.000
S32.30 Fracture of ilium (closed)	0.006	0.994	0.000
E10.8 With unspecified complications	0.006	0.994	0.000
E10.5 With peripheral circulatory complications	0.006	0.994	0.000
E10.1 With ketoacidosis	0.006	0.994	0.000
D76.3 Other histiocytosis syndromes	0.005	0.994	0.000
S32.4 Fracture of acetabulum	0.005	0.994	0.000
S80.9 Superficial injury of lower leg, unspecified	0.005	0.995	0.000
E10.7 With multiple complications	0.005	0.995	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.005	0.995	0.000
D72 Other disorders of white blood cells	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
S32.40 Fracture of acetabulum (closed)	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
E16.2 Hypoglycaemia, unspecified	0.005	0.995	0.000
S32.2 Fracture of coccyx	0.005	0.995	0.000
A41.9 Septicaemia, unspecified	0.005	0.995	0.000
S32.11 Fracture of sacrum (open)	0.005	0.995	0.000
D73.1 Hypersplenism	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.004	0.995	0.000
D74.8 Other methaemoglobinaemias	0.004	0.995	0.000
D74.0 Congenital methaemoglobinaemia	0.004	0.995	0.000
Z36 Antenatal screening	0.000	0.995	0.005
K22.4 Dyskinesia of oesophagus	0.005	0.995	0.000
S32.51 Fracture of pubis (open)	0.004	0.995	0.000
Z36.8 Other antenatal screening	0.000	0.995	0.005
S32.7 Multiple fractures of lumbar spine and pelvis	0.004	0.995	0.000
B34 Viral infection of unspecified site	0.004	0.995	0.000
S32.31 Fracture of ilium (open)	0.004	0.996	0.000
Y43.9 Primarily systemic agent, unspecified	0.004	0.996	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.996	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.996	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.996	0.000
Y43.2 Antineoplastic natural products	0.004	0.996	0.000
Y43.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
S80 Superficial injury of lower leg	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.004	0.996	0.000
D73.8 Other diseases of spleen	0.004	0.996	0.000
D73.4 Cyst of spleen	0.004	0.996	0.000
D73.3 Abscess of spleen	0.004	0.996	0.000
D73.2 Chronic congestive splenomegaly	0.004	0.996	0.000
E10.0 With coma	0.004	0.996	0.000
S32.01 Fracture of lumbar vertebra (open)	0.004	0.996	0.000
D75.2 Essential thrombocytosis	0.004	0.996	0.000
D72.1 Eosinophilia	0.004	0.996	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.996	0.004
B34.8 Other viral infections of unspecified site	0.004	0.996	0.000
D73.5 Infarction of spleen	0.004	0.996	0.000
S32.41 Fracture of acetabulum (open)	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
D72.9 Disorder of white blood cells, unspecified	0.004	0.996	0.000
D72.0 Genetic anomalies of leukocytes	0.004	0.996	0.000
S80.8 Other superficial injuries of lower leg	0.004	0.996	0.000
D73.0 Hyposplenism	0.004	0.996	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.996	0.004
S80.1 Contusion of other and unspecified parts of lower leg	0.004	0.996	0.000
S32.21 Fracture of coccyx (open)	0.003	0.996	0.000
S32.20 Fracture of coccyx (closed)	0.003	0.996	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.004	0.996	0.000
S80.0 Contusion of knee	0.004	0.996	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.996	0.004
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.004	0.996	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.996	0.003
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.996	0.004
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.996	0.004
M06.9 Rheumatoid arthritis, unspecified	0.004	0.996	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.003	0.996	0.000
B34.4 Papovirus infection, unspecified	0.003	0.996	0.000
B34.3 Parvovirus infection, unspecified	0.003	0.996	0.000
B34.2 Coronavirus infection, unspecified	0.003	0.996	0.000
B34.1 Enterovirus infection, unspecified	0.003	0.996	0.000
B34.0 Adenovirus infection, unspecified	0.003	0.996	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.996	0.004
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
C78.7 Secondary malignant neoplasm of liver	0.003	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.997	0.000
N81.3 Complete uterovaginal prolapse	0.003	0.997	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.997	0.003
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
A41 Other septicaemia	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
D59.1 Other autoimmune haemolytic anaemias	0.003	0.997	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.997	0.000
O36.6 Maternal care for excessive foetal growth	0.000	0.997	0.003
R50.8 Other specified fever	0.003	0.997	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.997	0.000
C25.9 Pancreas, unspecified	0.003	0.997	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.002	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.998	0.000
E16.3 Increased secretion of glucagon	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
A41.4 Septicaemia due to anaerobes	0.002	0.998	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.002	0.998	0.000
L73.2 Hidradenitis suppurativa	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
S89 Other and unspecified injuries of lower leg	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.998	0.002
S83.2 Tear of meniscus, current	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.998	0.002
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
S89.8 Other specified injuries of lower leg	0.002	0.998	0.000
E12 Malnutrition-related diabetes mellitus	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
C43 Malignant melanoma of skin	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
C25.0 Head of pancreas	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.002	0.998	0.000
E66.8 Other obesity	0.002	0.998	0.000
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
Z73.5 Social role conflict, not elsewhere classified	0.002	0.998	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.002	0.998	0.000
Z73.2 Lack of relaxation and leisure	0.002	0.998	0.000
Z73.1 Accentuation of personality traits	0.002	0.998	0.000
Z73.0 Burn-out	0.002	0.998	0.000
F32.0 Mild depressive episode	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
C25.2 Tail of pancreas	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
L65.9 Nonscarring hair loss, unspecified	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
K61.0 Anal abscess	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.998	0.002
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
E14.1 With ketoacidosis	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
Z37.2 Twins, both liveborn	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
B25-B34 Other viral diseases	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
E12.9 Without complications	0.001	0.998	0.000
E12.8 With unspecified complications	0.001	0.998	0.000
E12.7 With multiple complications	0.001	0.998	0.000
E12.6 With other specified complications	0.001	0.998	0.000
E12.5 With peripheral circulatory complications	0.001	0.998	0.000
E12.4 With neurological complications	0.001	0.998	0.000
E12.3 With ophthalmic complications	0.001	0.998	0.000
E12.2 With renal complications	0.001	0.998	0.000
E12.1 With ketoacidosis	0.001	0.998	0.000
E12.0 With coma	0.001	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
E14 Unspecified diabetes mellitus	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
C43.8 Overlapping malignant melanoma of skin	0.002	0.998	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.002	0.998	0.000
C43.0 Malignant melanoma of lip	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.002	0.998	0.000
N81.2 Incomplete uterovaginal prolapse	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
E11.1 With ketoacidosis	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
K07.2 Anomalies of dental arch relationship	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.001	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.001	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.001	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.998	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
S82.4 Fracture of fibula alone	0.002	0.998	0.000
I49 Other cardiac arrhythmias	0.000	0.998	0.002
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
L60.8 Other nail disorders	0.002	0.998	0.000
N73 Other female pelvic inflammatory diseases	0.000	0.998	0.002
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
A41.8 Other specified septicaemia	0.001	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.002	0.998	0.000
R03.1 Nonspecific low blood-pressure reading	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.001	0.998	0.000
Q83 Congenital malformations of breast	0.001	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
Q54.8 Other hypospadias	0.001	0.998	0.000
Q54.4 Congenital chordee	0.001	0.998	0.000
Q54.3 Hypospadias, perineal	0.001	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.001	0.998	0.000
Q54.1 Hypospadias, penile	0.001	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.001	0.998	0.000
C25.1 Body of pancreas	0.001	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
M06.34 Rheumatoid nodule (Hand)	0.001	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.001	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.998	0.000
A31.0 Pulmonary mycobacterial infection	0.001	0.998	0.000
E14.6 With other specified complications	0.001	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.998	0.000
I07.8 Other tricuspid valve diseases	0.001	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.998	0.000
I07.0 Tricuspid stenosis	0.001	0.998	0.000
Q83.8 Other congenital malformations of breast	0.001	0.998	0.000
S82.0 Fracture of patella	0.001	0.998	0.000
B33 Other viral diseases, not elsewhere classified	0.001	0.998	0.000
B30 Viral conjunctivitis	0.001	0.998	0.000
B26 Mumps	0.001	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.001	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.001	0.998	0.000
Y58 Bacterial vaccines	0.001	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.998	0.000
Q50-Q56 Congenital malformations of genital organs	0.001	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.001	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.998	0.000
E14.8 With unspecified complications	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations