TreeWAS – Variant ID: rs11895026

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D04.7 Skin of lower limb, including hip	0.023	0.977	0.000
D04 Carcinoma in situ of skin	0.019	0.981	0.000
D04.5 Skin of trunk	0.017	0.982	0.000
D03 Melanoma in situ	0.017	0.983	0.000
D00-D09 In situ neoplasms	0.017	0.983	0.000
D03.5 Melanoma in situ of trunk	0.016	0.984	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.016	0.984	0.000
D07.5 Prostate	0.016	0.984	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.016	0.984	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.015	0.985	0.000
D04.1 Skin of eyelid, including canthus	0.015	0.985	0.000
D04.8 Skin of other sites	0.014	0.986	0.000
D04.0 Skin of lip	0.014	0.986	0.000
D04.6 Skin of upper limb, including shoulder	0.014	0.986	0.000
D03.0 Melanoma in situ of lip	0.014	0.986	0.000
D04.3 Skin of other and unspecified parts of face	0.014	0.986	0.000
D04.9 Skin, unspecified	0.014	0.986	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.013	0.987	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.013	0.987	0.000
D09 Carcinoma in situ of other and unspecified sites	0.013	0.987	0.000
D04.2 Skin of ear and external auricular canal	0.013	0.987	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.013	0.987	0.000
D03.9 Melanoma in situ, unspecified	0.012	0.987	0.000
D03.8 Melanoma in situ of other sites	0.012	0.987	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.012	0.987	0.000
D07.4 Penis	0.012	0.988	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.012	0.988	0.000
D07.1 Vulva	0.012	0.988	0.000
D07.6 Other and unspecified male genital organs	0.012	0.988	0.000
D07.3 Other and unspecified female genital organs	0.012	0.988	0.000
D07.0 Endometrium	0.012	0.988	0.000
D07.2 Vagina	0.011	0.989	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.011	0.989	0.000
D00.0 Lip, oral cavity and pharynx	0.010	0.989	0.000
D02.0 Larynx	0.010	0.990	0.000
D01.3 Anus and anal canal	0.010	0.990	0.000
D09.0 Bladder	0.010	0.990	0.000
D09.1 Other and unspecified urinary organs	0.010	0.990	0.000
T79.7 Traumatic subcutaneous emphysema	0.010	0.990	0.000
C78.7 Secondary malignant neoplasm of liver	0.010	0.990	0.000
D00.2 Stomach	0.010	0.990	0.000
D00.1 Oesophagus	0.010	0.990	0.000
D02.4 Respiratory system, unspecified	0.010	0.990	0.000
D02.3 Other parts of respiratory system	0.010	0.990	0.000
D02.2 Bronchus and lung	0.010	0.990	0.000
D02.1 Trachea	0.010	0.990	0.000
D09.9 Carcinoma in situ, unspecified	0.010	0.990	0.000
D09.7 Carcinoma in situ of other specified sites	0.010	0.990	0.000
D09.3 Thyroid and other endocrine glands	0.010	0.990	0.000
D09.2 Eye	0.010	0.990	0.000
D03.4 Melanoma in situ of scalp and neck	0.009	0.990	0.000
D01.9 Digestive organ, unspecified	0.009	0.990	0.000
D01.7 Other specified digestive organs	0.009	0.990	0.000
D01.5 Liver, gallbladder and bile ducts	0.009	0.990	0.000
D01.4 Other and unspecified parts of intestine	0.009	0.990	0.000
D01.1 Rectosigmoid junction	0.009	0.990	0.000
D01.0 Colon	0.009	0.990	0.000
D06 Carcinoma in situ of cervix uteri	0.009	0.991	0.000
D01.2 Rectum	0.009	0.991	0.000
D04.4 Skin of scalp and neck	0.009	0.991	0.000
N28.8 Other specified disorders of kidney and ureter	0.009	0.991	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.009	0.991	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.992	0.008
T79.3 Post-traumatic wound infection, not elsewhere classified	0.008	0.992	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.992	0.008
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.008	0.992	0.000
D06.0 Endocervix	0.008	0.992	0.000
T79.8 Other early complications of trauma	0.008	0.992	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.008	0.992	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.992	0.008
D06.7 Other parts of cervix	0.007	0.993	0.000
D06.1 Exocervix	0.007	0.993	0.000
C78.0 Secondary malignant neoplasm of lung	0.007	0.993	0.000
T79.5 Traumatic anuria	0.007	0.993	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.007	0.993	0.000
F33 Recurrent depressive disorder	0.000	0.993	0.007
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.007	0.993	0.000
T79.9 Unspecified early complication of trauma	0.006	0.993	0.000
T79.4 Traumatic shock	0.006	0.993	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.006	0.993	0.000
T79.1 Fat embolism (traumatic)	0.006	0.993	0.000
T79.0 Air embolism (traumatic)	0.006	0.993	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.993	0.006
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.994	0.006
N87.0 Mild cervical dysplasia	0.000	0.994	0.006
M89.0 Algoneurodystrophy	0.006	0.994	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.006	0.994	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.006	0.994	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.994	0.006
T79.6 Traumatic ischaemia of muscle	0.005	0.994	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.995	0.005
M89.8 Other specified disorders of bone	0.005	0.995	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.005	0.995	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.995	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.995	0.005
D86 Sarcoidosis	0.000	0.995	0.005
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.005	0.995	0.000
J34.2 Deviated nasal septum	0.005	0.995	0.000
M89.04 Algoneurodystrophy (Hand)	0.005	0.995	0.000
F33.8 Other recurrent depressive disorders	0.000	0.995	0.005
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.995	0.005
M89.07 Algoneurodystrophy (Ankle and foot)	0.005	0.995	0.000
M89 Other disorders of bone	0.005	0.995	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.995	0.005
M89.88 Other specified disorders of bone (Other)	0.005	0.995	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.005	0.995	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.005	0.995	0.000
M89.03 Algoneurodystrophy (Forearm)	0.005	0.995	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.005	0.995	0.000
M89.08 Algoneurodystrophy (Other)	0.004	0.996	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.004	0.996	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.004	0.996	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.996	0.004
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.996	0.004
D23.1 Skin of eyelid, including canthus	0.004	0.996	0.000
C78.2 Secondary malignant neoplasm of pleura	0.004	0.996	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.004	0.996	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.004	0.996	0.000
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
M89.83 Other specified disorders of bone (Forearm)	0.004	0.996	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.004	0.996	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.004	0.996	0.000
M89.5 Osteolysis	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.996	0.004
M89.09 Algoneurodystrophy (Site unspecified)	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.000	0.996	0.004
M89.6 Osteopathy after poliomyelitis	0.004	0.996	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.004	0.996	0.000
M89.2 Other disorders of bone development and growth	0.004	0.996	0.000
M89.1 Epiphyseal arrest	0.004	0.996	0.000
J98.4 Other disorders of lung	0.004	0.996	0.000
M89.3 Hypertrophy of bone	0.004	0.996	0.000
T79-T79 Certain early complications of trauma	0.004	0.996	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.004	0.996	0.000
D23.0 Skin of lip	0.004	0.996	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.996	0.000
D29.1 Prostate	0.003	0.997	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
D23.7 Skin of lower limb, including hip	0.003	0.997	0.000
D05 Carcinoma in situ of breast	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
M89.59 Osteolysis (Site unspecified)	0.003	0.997	0.000
M89.58 Osteolysis (Other)	0.003	0.997	0.000
M89.57 Osteolysis (Ankle and foot)	0.003	0.997	0.000
M89.56 Osteolysis (Lower leg)	0.003	0.997	0.000
M89.54 Osteolysis (Hand)	0.003	0.997	0.000
M89.53 Osteolysis (Forearm)	0.003	0.997	0.000
M89.52 Osteolysis (Upper arm)	0.003	0.997	0.000
M89.51 Osteolysis (Shoulder region)	0.003	0.997	0.000
M89.50 Osteolysis (Multiple sites)	0.003	0.997	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.003	0.997	0.000
J33.9 Nasal polyp, unspecified	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.003	0.997	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.003	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.003	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.003	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.003	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.003	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.003	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.003	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.003	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.003	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.003	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.003	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.003	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.003	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.003	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.003	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.003	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.003	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.003	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.003	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.003	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.003	0.997	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.003	0.997	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.003	0.997	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.003	0.997	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.003	0.997	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.003	0.997	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.003	0.997	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.003	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.003	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.003	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.003	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.003	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.003	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.003	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.003	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.003	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.003	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.003	0.997	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.003	0.997	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.997	0.003
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
M89.39 Hypertrophy of bone (Site unspecified)	0.003	0.997	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.003	0.997	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.003	0.997	0.000
M89.34 Hypertrophy of bone (Hand)	0.003	0.997	0.000
M89.33 Hypertrophy of bone (Forearm)	0.003	0.997	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.003	0.997	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.003	0.997	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.003	0.997	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
M89.38 Hypertrophy of bone (Other)	0.003	0.997	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
D23 Other benign neoplasms of skin	0.003	0.997	0.000
C34.0 Main bronchus	0.003	0.997	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.997	0.003
N28 Other disorders of kidney and ureter, not elsewhere classified	0.003	0.997	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.997	0.003
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.997	0.003
D05.7 Other carcinoma in situ of breast	0.003	0.997	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.003	0.997	0.000
T88.4 Failed or difficult intubation	0.000	0.997	0.003
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
M88.9 Paget's disease of bone, unspecified	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.997	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.997	0.003
S02.21 Fracture of nasal bones (open)	0.002	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
M88 Paget's disease of bone [osteitis deformans]	0.002	0.997	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.997	0.003
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.997	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.997	0.000
M86-M90 Other osteopathies	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.997	0.000
T88.9 Complication of surgical and medical care, unspecified	0.000	0.997	0.002
N87 Dysplasia of cervix uteri	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.002	0.998	0.000
T88.5 Other complications of anaesthesia	0.000	0.998	0.002
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.998	0.002
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.998	0.002
T88.0 Infection following immunisation	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.000	0.998	0.002
K29.3 Chronic superficial gastritis	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.002	0.998	0.000
T88.2 Shock due to anaesthesia	0.000	0.998	0.002
D23.9 Skin, unspecified	0.002	0.998	0.000
C34 Malignant neoplasm of bronchus and lung	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
J39.2 Other diseases of pharynx	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.998	0.002
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.002	0.998	0.000
D84 Other immunodeficiencies	0.000	0.998	0.002
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.002	0.998	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.002	0.998	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.002	0.998	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.002	0.998	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.998	0.002
N73.6 Female pelvic peritoneal adhesions	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
M88.8 Paget's disease of other bones	0.002	0.998	0.000
M88.0 Paget's disease of skull	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.002	0.998	0.000
D23.5 Skin of trunk	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.002	0.998	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
C34.8 Overlapping lesion of bronchus and lung	0.002	0.998	0.000
D23.4 Skin of scalp and neck	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
D29 Benign neoplasm of male genital organs	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
M86 Osteomyelitis	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
M87 Osteonecrosis	0.002	0.998	0.000
N27 Small kidney of unknown cause	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
L71.9 Rosacea, unspecified	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
K57.3 Diverticular disease of large intestine without perforation or abscess	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
D29.3 Epididymis	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
D84.1 Defects in the complement system	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.998	0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
N25-N29 Other disorders of kidney and ureter	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.002
K38.8 Other specified diseases of appendix	0.000	0.998	0.002
N27.1 Small kidney, bilateral	0.002	0.998	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.998	0.002
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.998	0.002
M86.8 Other osteomyelitis	0.002	0.998	0.000
N27.0 Small kidney, unilateral	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
C34.2 Middle lobe, bronchus or lung	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
D23.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.000	0.998	0.002
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
M88.09 Paget's disease of skull-Site unspec	0.002	0.998	0.000
M88.08 Paget's disease of skull-Other	0.002	0.998	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.002	0.998	0.000
M88.06 Paget's disease of skull-Lower Leg	0.002	0.998	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.002	0.998	0.000
M88.04 Paget's disease of skull-Hand	0.002	0.998	0.000
M88.03 Paget's disease of skull-Forearm	0.002	0.998	0.000
M88.02 Paget's disease of skull-Upper arm	0.002	0.998	0.000
M88.01 Paget's disease of skull-Shldr region	0.002	0.998	0.000
M88.00 Paget's disease of skull-Mult sites	0.002	0.998	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.002	0.998	0.000
M88.88 Paget's disease of other bones (Other)	0.002	0.998	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.002	0.998	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.002	0.998	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.002	0.998	0.000
M88.84 Paget's disease of other bones (Hand)	0.002	0.998	0.000
M88.83 Paget's disease of other bones (Forearm)	0.002	0.998	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.002	0.998	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.002	0.998	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.002	0.998	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.998	0.002
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.002	0.998	0.000
D29.0 Penis	0.002	0.998	0.000
L60.8 Other nail disorders	0.002	0.998	0.000
M48.0 Spinal stenosis	0.000	0.998	0.002
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.002	0.998	0.000
S00.8 Superficial injury of other parts of head	0.000	0.998	0.002
S02.5 Fracture of tooth	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
N26 Unspecified contracted kidney	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
D29.2 Testis	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.998	0.001
D81.8 Other combined immunodeficiencies	0.000	0.998	0.001
D81.7 Major histocompatibility complex class II deficiency	0.000	0.998	0.001
D81.6 Major histocompatibility complex class I deficiency	0.000	0.998	0.001
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.998	0.001
D81.4 Nezelof's syndrome	0.000	0.998	0.001
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.998	0.001
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.998	0.001
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.998	0.001
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.998	0.001
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.998	0.001
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.998	0.001
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.998	0.001
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.998	0.001
D82.2 Immunodeficiency with short-limbed stature	0.000	0.998	0.001
D82.0 Wiskott-Aldrich syndrome	0.000	0.998	0.001
D29.9 Male genital organ, unspecified	0.002	0.998	0.000
D29.7 Other male genital organs	0.002	0.998	0.000
D82.1 Di George's syndrome	0.000	0.998	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.002	0.998	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
C50.2 Upper-inner quadrant of breast	0.002	0.998	0.000
M87.8 Other osteonecrosis	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.998	0.000
S72.7 Multiple fractures of femur	0.002	0.998	0.000
D29.4 Scrotum	0.002	0.998	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.001	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.001	0.998	0.000
M86.3 Chronic multifocal osteomyelitis	0.001	0.998	0.000
M86.2 Subacute osteomyelitis	0.001	0.998	0.000
M86.1 Other acute osteomyelitis	0.001	0.998	0.000
M86.0 Acute haematogenous osteomyelitis	0.001	0.998	0.000
N27.9 Small kidney, unspecified	0.002	0.998	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
S02.31 Fracture of orbital floor (open)	0.001	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
M87.3 Other secondary osteonecrosis	0.001	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.001	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.998	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.001	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.998	0.000
J38.4 Oedema of larynx	0.000	0.998	0.002
M92.6 Juvenile osteochondrosis of tarsus	0.002	0.998	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.001	0.998	0.000
S02.61 Fracture of mandible (open)	0.001	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
M25.53 Pain in joint (Forearm)	0.000	0.998	0.002
M86.89 Other osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.88 Other osteomyelitis (Other)	0.001	0.998	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.84 Other osteomyelitis (Hand)	0.001	0.998	0.000
M86.83 Other osteomyelitis (Forearm)	0.001	0.998	0.000
M86.82 Other osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.001	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M48.04 Spinal stenosis (Thoracic region)	0.000	0.998	0.001
D23.2 Skin of ear and external auricular canal	0.001	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.001	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.998	0.000
M90.0 Tuberculosis of bone	0.001	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
S02.8 Fractures of other skull and facial bones	0.001	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.001	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.998	0.000
M86.6 Other chronic osteomyelitis	0.001	0.998	0.000
S02.0 Fracture of vault of skull	0.001	0.998	0.000
N25 Disorders resulting from impaired renal tubular function	0.001	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.001
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.001
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.001
S72.91 Fracture of femur, part unspecified (open)	0.001	0.998	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
M92.7 Juvenile osteochondrosis of metatarsus	0.001	0.998	0.000
Z90.2 Acquired absence of lung [part of]	0.002	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.001	0.998	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.000	0.998	0.002
J38.7 Other diseases of larynx	0.000	0.998	0.002
K56.2 Volvulus	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.998	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.998	0.001
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.001	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.998	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations