TreeWAS – Variant ID: rs1192691

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.986	0.014
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.988	0.012
K25 Gastric ulcer	0.000	0.990	0.010
K25.7 Chronic without haemorrhage or perforation	0.000	0.990	0.010
K25.3 Acute without haemorrhage or perforation	0.000	0.991	0.009
K25.2 Acute with both haemorrhage and perforation	0.000	0.992	0.008
K25.1 Acute with perforation	0.000	0.992	0.008
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.992	0.008
K25.5 Chronic or unspecified with perforation	0.000	0.992	0.008
K25.4 Chronic or unspecified with haemorrhage	0.000	0.992	0.008
K25.0 Acute with haemorrhage	0.000	0.992	0.008
M79.09 Rheumatism, unspecified (Site unspecified)	0.007	0.993	0.000
H33.2 Serous retinal detachment	0.007	0.993	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.007	0.993	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.006	0.994	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.994	0.006
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.994	0.006
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.994	0.006
K63.3 Ulcer of intestine	0.000	0.995	0.005
T82.3 Mechanical complication of other vascular grafts	0.000	0.995	0.005
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.995	0.005
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.995	0.005
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.995	0.005
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.995	0.005
O42.9 Premature rupture of membranes, unspecified	0.005	0.995	0.000
O42 Premature rupture of membranes	0.004	0.995	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.004	0.996	0.000
M79.0 Rheumatism, unspecified	0.004	0.996	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.004	0.996	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.004	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
S83.6 Sprain and strain of other and unspecified parts of knee	0.004	0.996	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.004	0.996	0.000
S83.7 Injury to multiple structures of knee	0.003	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.004	0.996	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.003	0.996	0.000
J06.9 Acute upper respiratory infection, unspecified	0.003	0.996	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.003	0.997	0.000
S83.1 Dislocation of knee	0.003	0.997	0.000
S83.0 Dislocation of patella	0.003	0.997	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.003	0.997	0.000
M79.08 Rheumatism, unspecified (Other)	0.003	0.997	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M79.04 Rheumatism, unspecified (Hand)	0.003	0.997	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.003	0.997	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
S83.3 Tear of articular cartilage of knee, current	0.003	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.997	0.003
S82.40 Fracture of fibula alone (closed)	0.003	0.997	0.000
J43.9 Emphysema, unspecified	0.000	0.997	0.003
S80.8 Other superficial injuries of lower leg	0.003	0.997	0.000
A08.4 Viral intestinal infection, unspecified	0.003	0.997	0.000
T42.1 Iminostilbenes	0.000	0.997	0.003
S80.9 Superficial injury of lower leg, unspecified	0.003	0.997	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.003	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
S82.4 Fracture of fibula alone	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
R00.0 Tachycardia, unspecified	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
S89.8 Other specified injuries of lower leg	0.003	0.997	0.000
S87 Crushing injury of lower leg	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.003	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
S89.7 Multiple injuries of lower leg	0.002	0.997	0.000
S89.1 Other specified injuries of lower leg	0.002	0.997	0.000
S89.0 Multiple injuries of lower leg	0.002	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
L02 Cutaneous abscess, furuncle and carbuncle	0.003	0.997	0.000
R06.8 Other and unspecified abnormalities of breathing	0.003	0.997	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.997	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.003	0.997	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.997	0.003
S80.0 Contusion of knee	0.002	0.997	0.000
S82.1 Fracture of upper end of tibia	0.002	0.997	0.000
T42.0 Hydantoin derivatives	0.000	0.997	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.002
O36.9 Maternal care for foetal problem, unspecified	0.002	0.997	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.002	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
O32.4 Maternal care for high head at term	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
I63.8 Other cerebral infarction	0.000	0.998	0.002
H33 Retinal detachments and breaks	0.002	0.998	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
E87.6 Hypokalaemia	0.002	0.998	0.000
Y84.4 Aspiration of fluid	0.000	0.998	0.002
O47 False labour	0.002	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.998	0.002
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
C77.2 Intra-abdominal lymph nodes	0.002	0.998	0.000
O43 Placental disorders	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
Y95 Nosocomial condition	0.002	0.998	0.000
Y84.6 Urinary catheterisation	0.000	0.998	0.002
I63 Cerebral infarction	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.000	0.998	0.002
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
O31 Complications specific to multiple gestation	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.998	0.002
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
Y84.0 Cardiac catheterisation	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
J35.0 Chronic tonsillitis	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
Y84.3 Shock therapy	0.000	0.998	0.002
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
O43.8 Other placental disorders	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
O30 Multiple gestation	0.002	0.998	0.000
O40 Polyhydramnios	0.002	0.998	0.000
O43.9 Placental disorder, unspecified	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.000	0.998	0.002
Y84.1 Kidney dialysis	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
S82.71 Multiple fractures of lower leg (open)	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
J06 Acute upper respiratory infections of multiple and unspecified sites	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
O46.9 Antepartum haemorrhage, unspecified	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
Y84.7 Blood-sampling	0.000	0.998	0.002
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
O47.9 False labour, unspecified	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
J43.2 Centrilobular emphysema	0.000	0.998	0.002
N81.4 Uterovaginal prolapse, unspecified	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
H35.7 Separation of retinal layers	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
O31.1 Continuing pregnancy after abortion of one foetus or more	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
Y84.5 Insertion of gastric or duodenal sound	0.000	0.998	0.002
J43 Emphysema	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
O33.9 Maternal care for disproportion, unspecified	0.002	0.998	0.000
O33.8 Maternal care for disproportion of other origin	0.002	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.002	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.002	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.002	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.002	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.002	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.002	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
O31.0 Papyraceous foetus	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
T90.4 Sequelae of injury of eye and orbit	0.000	0.998	0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.001	0.998	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.001	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.001	0.998	0.000
Y84.9 Medical procedure, unspecified	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
O31.8 Other complications specific to multiple gestation	0.001	0.998	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.001	0.998	0.000
O45.8 Other premature separation of placenta	0.001	0.998	0.000
O45.0 Premature separation of placenta with coagulation defect	0.001	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
O43.1 Malformation of placenta	0.001	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
H33.4 Traction detachment of retina	0.001	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.001
T45.4 Iron and its compounds	0.000	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
S82.61 Fracture of lateral malleolus (open)	0.001	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
J06.0 Acute laryngopharyngitis	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.001	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
O30.9 Multiple gestation, unspecified	0.001	0.998	0.000
O30.8 Other multiple gestation	0.001	0.998	0.000
O30.2 Quadruplet pregnancy	0.001	0.998	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
J06.8 Other acute upper respiratory infections of multiple sites	0.001	0.998	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.002	0.998	0.000
H35 Other retinal disorders	0.002	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.001	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.001
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.998	0.001
O34.7 Maternal care for abnormality of vulva and perineum	0.001	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.001	0.998	0.000
S81.0 Open wound of knee	0.001	0.998	0.000
T36.4 Tetracyclines	0.000	0.998	0.001
T36.0 Penicillins	0.000	0.998	0.001
T47.2 Stimulant laxatives	0.000	0.998	0.001
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.001
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.001	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.001	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.001	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.001	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.001	0.998	0.000
O45.9 Premature separation of placenta, unspecified	0.001	0.998	0.000
T36.3 Macrolides	0.000	0.998	0.001
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.001	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
T47.7 Emetics	0.000	0.998	0.001
T47.5 Digestants	0.000	0.998	0.001
T47.3 Saline and osmotic laxatives	0.000	0.998	0.001
Y84.8 Other medical procedures	0.000	0.998	0.002
O48 Prolonged pregnancy	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.001	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.002	0.998	0.000
J43.1 Panlobular emphysema	0.000	0.998	0.001
J43.0 MacLeod's syndrome	0.000	0.998	0.001
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.001	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.001
T36.8 Other systemic antibiotics	0.000	0.998	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.001
T36.6 Rifamycins	0.000	0.998	0.001
T36.5 Aminoglycosides	0.000	0.998	0.001
T36.2 Chloramphenicol group	0.000	0.998	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.001
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
T47.4 Other laxatives	0.000	0.998	0.001
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.001	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.001	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.001	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.001	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.001
S82.00 Fracture of patella (closed)	0.001	0.998	0.000
F52.2 Failure of genital response	0.000	0.998	0.001
J43.8 Other emphysema	0.000	0.998	0.001
O34.0 Maternal care for congenital malformation of uterus	0.001	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
T37.5 Antiviral drugs	0.000	0.998	0.001
T37.4 Anthelminthics	0.000	0.998	0.001
T37.3 Other antiprotozoal drugs	0.000	0.998	0.001
T37.1 Antimycobacterial drugs	0.000	0.998	0.001
T37.0 Sulphonamides	0.000	0.998	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.001
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.001
H35.6 Retinal haemorrhage	0.001	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
T49.9 Topical agent, unspecified	0.000	0.998	0.001
T49.8 Other topical agents	0.000	0.998	0.001
T49.7 Dental drugs, topically applied	0.000	0.998	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.001
T49.2 Local astringents and local detergents	0.000	0.998	0.001
T49.1 Antipruritics	0.000	0.998	0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.999	0.001
M35.3 Polymyalgia rheumatica	0.001	0.999	0.000
S81.8 Open wound of other parts of lower leg	0.001	0.999	0.000
T41.5 Therapeutic gases	0.000	0.999	0.001
T41.4 Anaesthetic, unspecified	0.000	0.999	0.001
T41.3 Local anaesthetics	0.000	0.999	0.001
T41.1 Intravenous anaesthetics	0.000	0.999	0.001
T41.0 Inhaled anaesthetics	0.000	0.999	0.001
C83 Diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
O34.3 Maternal care for cervical incompetence	0.001	0.999	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.001	0.999	0.000
H35.1 Retinopathy of prematurity	0.001	0.999	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.999	0.001
S32.50 Fracture of pubis (closed)	0.001	0.999	0.000
H35.5 Hereditary retinal dystrophy	0.001	0.999	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.999	0.001
J92.9 Pleural plaque without asbestos	0.000	0.999	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.999	0.001
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.999	0.001
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.999	0.001
T44.0 Anticholinesterase agents	0.000	0.999	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
T48.4 Expectorants	0.000	0.999	0.001
T48.3 Antitussives	0.000	0.999	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.999	0.001
T48.0 Oxytocic drugs	0.000	0.999	0.001
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.999	0.001
S82.20 Fracture of shaft of tibia (closed)	0.001	0.999	0.000
G43.9 Migraine, unspecified	0.001	0.999	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.001	0.999	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
H35.9 Retinal disorder, unspecified	0.001	0.999	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.001	0.999	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.001	0.999	0.000
O30.0 Twin pregnancy	0.001	0.999	0.000
T38.0 Glucocorticoids and synthetic analogues	0.000	0.999	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.001	0.999	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.999	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
T48.5 Anti-common-cold drugs	0.000	0.999	0.001
Z93.2 Ileostomy status	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.001	0.999	0.000
H35.4 Peripheral retinal degeneration	0.001	0.999	0.000
M41.9 Scoliosis, unspecified	0.000	0.999	0.001
T38.5 Other oestrogens and progestogens	0.000	0.999	0.001
Z83.5 Family history of eye and ear disorders	0.001	0.999	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.999	0.001
S82.30 Fracture of lower end of tibia (closed)	0.001	0.999	0.000
C83.5 Lymphoblastic (diffuse)	0.001	0.999	0.000
C83.2 Mixed small and large cell (diffuse)	0.001	0.999	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.999	0.001
J30.4 Allergic rhinitis, unspecified	0.000	0.999	0.001
T38.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
T38.7 Androgens and anabolic congeners	0.000	0.999	0.001
T38.4 Oral contraceptives	0.000	0.999	0.001
T38.2 Antithyroid drugs	0.000	0.999	0.001
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.001	0.999	0.000
C83.6 Undifferentiated (diffuse)	0.001	0.999	0.000
C83.4 Immunoblastic (diffuse)	0.001	0.999	0.000
H35.2 Other proliferative retinopathy	0.001	0.999	0.000
O72.1 Other immediate postpartum haemorrhage	0.001	0.999	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
T38.1 Thyroid hormones and substitutes	0.000	0.999	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
D23.9 Skin, unspecified	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.999	0.001
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
O41.0 Oligohydramnios	0.001	0.999	0.001
T78.3 Angioneurotic oedema	0.001	0.999	0.000
H30-H36 Disorders of choroid and retina	0.001	0.999	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.999	0.001
C83.1 Small cleaved cell (diffuse)	0.001	0.999	0.000
T50.8 Diagnostic agents	0.000	0.999	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.999	0.001
T50.5 Appetite depressants	0.000	0.999	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.999	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.999	0.001
H31 Other disorders of choroid	0.001	0.999	0.000
H30 Chorioretinal inflammation	0.001	0.999	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.999	0.001
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.999	0.001
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.999	0.001
M94.8 Other specified disorders of cartilage	0.000	0.999	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.999	0.001
M10.94 Gout, unspecified (Hand)	0.000	0.999	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.999	0.001
T39.0 Salicylates	0.000	0.999	0.001
T50.4 Drugs affecting uric acid metabolism	0.000	0.999	0.001
I61 Intracerebral haemorrhage	0.000	0.999	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
M94.26 Chondromalacia (Lower leg)	0.000	0.999	0.001
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
H30.9 Chorioretinal inflammation, unspecified	0.001	0.999	0.000
H31.1 Choroidal degeneration	0.001	0.999	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.999	0.001
J35.1 Hypertrophy of tonsils	0.000	0.999	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.999	0.001
K74 Fibrosis and cirrhosis of liver	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations