TreeWAS – Variant ID: rs11945798

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I60-I69 Cerebrovascular diseases	0.131	0.869	0.000
I63 Cerebral infarction	0.127	0.873	0.000
I69 Sequelae of cerebrovascular disease	0.118	0.882	0.000
I63.9 Cerebral infarction, unspecified	0.117	0.883	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.117	0.883	0.000
I67 Other cerebrovascular diseases	0.117	0.883	0.000
I62 Other nontraumatic intracranial haemorrhage	0.114	0.886	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.113	0.887	0.000
I60 Subarachnoid haemorrhage	0.108	0.892	0.000
I65.2 Occlusion and stenosis of carotid artery	0.108	0.892	0.000
I63.8 Other cerebral infarction	0.105	0.895	0.000
I67.9 Cerebrovascular disease, unspecified	0.103	0.897	0.000
I61 Intracerebral haemorrhage	0.101	0.899	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.101	0.899	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.100	0.900	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.100	0.900	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.099	0.900	0.000
I67.1 Cerebral aneurysm, nonruptured	0.098	0.902	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.096	0.904	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.095	0.905	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.094	0.906	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.094	0.906	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.094	0.906	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.091	0.909	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.091	0.909	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.091	0.909	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.091	0.909	0.000
I69.3 Sequelae of cerebral infarction	0.090	0.909	0.000
I67.2 Cerebral atherosclerosis	0.089	0.911	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.086	0.914	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.085	0.915	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.084	0.916	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.084	0.916	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.084	0.916	0.000
I65.1 Occlusion and stenosis of basilar artery	0.084	0.916	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.084	0.916	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.084	0.916	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.084	0.916	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.084	0.916	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.084	0.916	0.000
I67.5 Moyamoya disease	0.084	0.916	0.000
I67.4 Hypertensive encephalopathy	0.084	0.916	0.000
I67.3 Progressive vascular leukoencephalopathy	0.084	0.916	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.084	0.916	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.083	0.917	0.000
I62.1 Nontraumatic extradural haemorrhage	0.082	0.918	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.080	0.920	0.000
I60.8 Other subarachnoid haemorrhage	0.078	0.922	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.078	0.922	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.078	0.922	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.078	0.922	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.078	0.922	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.078	0.922	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.075	0.925	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.073	0.926	0.000
I61.8 Other intracerebral haemorrhage	0.073	0.927	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.073	0.927	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.073	0.927	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.073	0.927	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.073	0.927	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.073	0.927	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.073	0.927	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.068	0.932	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.068	0.932	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.068	0.932	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.068	0.932	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.068	0.932	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.068	0.932	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.068	0.932	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.068	0.932	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.068	0.932	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.068	0.932	0.000
I68.0 Cerebral amyloid angiopathy	0.068	0.932	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.065	0.935	0.000
I67.8 Other specified cerebrovascular diseases	0.064	0.936	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.992	0.008
R04.2 Haemoptysis	0.007	0.993	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.994	0.006
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.005	0.995	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.995	0.005
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.995	0.005
R29.4 Clicking hip	0.000	0.995	0.004
R29.3 Abnormal posture	0.000	0.995	0.004
R29.2 Abnormal reflex	0.000	0.995	0.004
R29.1 Meningismus	0.000	0.995	0.004
R29.0 Tetany	0.000	0.995	0.004
R26 Abnormalities of gait and mobility	0.000	0.996	0.004
C78.0 Secondary malignant neoplasm of lung	0.000	0.996	0.004
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.996	0.004
R60.0 Localised oedema	0.000	0.996	0.004
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
R53 Malaise and fatigue	0.004	0.996	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.997	0.003
C34.3 Lower lobe, bronchus or lung	0.003	0.997	0.000
D06.9 Cervix, unspecified	0.000	0.997	0.003
R26.3 Immobility	0.000	0.997	0.003
R04 Haemorrhage from respiratory passages	0.003	0.997	0.000
R26.1 Paralytic gait	0.000	0.997	0.003
R26.0 Ataxic gait	0.000	0.997	0.003
I80 Phlebitis and thrombophlebitis	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.003	0.997	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.003	0.997	0.000
R27 Other lack of coordination	0.000	0.997	0.003
I80.8 Phlebitis and thrombophlebitis of other sites	0.003	0.997	0.000
I72 Other aneurysm	0.003	0.997	0.000
Chapter IX Diseases of the circulatory system	0.003	0.997	0.000
R04.0 Epistaxis	0.003	0.997	0.000
F10.1 Harmful use	0.003	0.997	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.003	0.997	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.003	0.997	0.000
R04.1 Haemorrhage from throat	0.003	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
I72.0 Aneurysm of carotid artery	0.003	0.997	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
H01.0 Blepharitis	0.000	0.997	0.003
I72.3 Aneurysm of iliac artery	0.002	0.997	0.000
I77.1 Stricture of artery	0.003	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.997	0.003
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.998	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
D06 Carcinoma in situ of cervix uteri	0.000	0.998	0.002
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
D05 Carcinoma in situ of breast	0.000	0.998	0.002
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.002	0.998	0.000
A41.9 Septicaemia, unspecified	0.000	0.998	0.002
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.998	0.002
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.998	0.002
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.998	0.002
I72.9 Aneurysm of unspecified site	0.002	0.998	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.002	0.998	0.000
I72.1 Aneurysm of artery of upper extremity	0.002	0.998	0.000
C34 Malignant neoplasm of bronchus and lung	0.002	0.998	0.000
I00-I02 Acute rheumatic fever	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.000	0.998	0.002
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I77.2 Rupture of artery	0.002	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
C44.7 Skin of lower limb, including hip	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
I77.6 Arteritis, unspecified	0.002	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.998	0.002
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.998	0.002
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.998	0.002
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.998	0.002
D06.7 Other parts of cervix	0.000	0.998	0.002
D06.1 Exocervix	0.000	0.998	0.002
D06.0 Endocervix	0.000	0.998	0.002
I87 Other disorders of veins	0.002	0.998	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998	0.000
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
I82.0 Budd-Chiari syndrome	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.998	0.002
D05.0 Lobular carcinoma in situ	0.000	0.998	0.002
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.998	0.002
I88 Nonspecific lymphadenitis	0.002	0.998	0.000
F10.0 Acute intoxication	0.002	0.998	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.998	0.002
I70 Atherosclerosis	0.002	0.998	0.000
I81 Portal vein thrombosis	0.002	0.998	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.002	0.998	0.000
Z82.3 Family history of stroke	0.002	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
D70 Agranulocytosis	0.000	0.998	0.002
I02 Rheumatic chorea	0.002	0.998	0.000
I01 Rheumatic fever with heart involvement	0.002	0.998	0.000
I00 Rheumatic fever without mention of heart involvement	0.002	0.998	0.000
I78 Diseases of capillaries	0.002	0.998	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.002	0.998	0.000
C34.8 Overlapping lesion of bronchus and lung	0.002	0.998	0.000
C34.2 Middle lobe, bronchus or lung	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
C18.7 Sigmoid colon	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.001	0.998	0.000
R25.3 Fasciculation	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.002
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
R55 Syncope and collapse	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
S09.9 Unspecified injury of head	0.000	0.998	0.002
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.002	0.998	0.000
I86 Varicose veins of other sites	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.998	0.002
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.002	0.998	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.998	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
H01 Other inflammation of eyelid	0.000	0.998	0.002
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.998	0.002
C34.0 Main bronchus	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
I87.8 Other specified disorders of veins	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
I87.9 Disorder of vein, unspecified	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
I87.0 Postphlebitic syndrome	0.002	0.998	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.998	0.002
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.001
I70.9 Generalised and unspecified atherosclerosis	0.001	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.001	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.001	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.001	0.998	0.000
I88.8 Other nonspecific lymphadenitis	0.001	0.998	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.001	0.998	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.001	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.001	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.998	0.000
I89.1 Lymphangitis	0.001	0.998	0.000
A41.8 Other specified septicaemia	0.000	0.998	0.002
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.000	0.998	0.002
A41 Other septicaemia	0.000	0.998	0.002
D00-D09 In situ neoplasms	0.000	0.998	0.002
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.998	0.001
I01.9 Acute rheumatic heart disease, unspecified	0.001	0.998	0.000
I01.8 Other acute rheumatic heart disease	0.001	0.998	0.000
I01.2 Acute rheumatic myocarditis	0.001	0.998	0.000
I01.1 Acute rheumatic endocarditis	0.001	0.998	0.000
I01.0 Acute rheumatic pericarditis	0.001	0.998	0.000
I02.9 Rheumatic chorea without heart involvement	0.001	0.998	0.000
I02.0 Rheumatic chorea with heart involvement	0.001	0.998	0.000
I70.0 Atherosclerosis of aorta	0.001	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.001	0.998	0.000
I78.8 Other diseases of capillaries	0.001	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.001	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.998	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I98.0 Cardiovascular syphilis	0.001	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.001	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.001
Z12.1 Special screening examination for neoplasm of intestinal tract	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
F10.3 Withdrawal state	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.001	0.998	0.000
F10.9 Unspecified mental and behavioural disorder	0.001	0.998	0.000
F10.8 Other mental and behavioural disorders	0.001	0.998	0.000
F10.7 Residual and late-onset psychotic disorder	0.001	0.998	0.000
F10.6 Amnesic syndrome	0.001	0.998	0.000
F10.5 Psychotic disorder	0.001	0.998	0.000
I86.8 Varicose veins of other specified sites	0.001	0.998	0.000
I86.3 Vulval varices	0.001	0.998	0.000
I86.2 Pelvic varices	0.001	0.998	0.000
I86.0 Sublingual varices	0.001	0.998	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.998	0.001
R25.1 Tremor, unspecified	0.000	0.998	0.001
I09 Other rheumatic heart diseases	0.001	0.998	0.000
I06 Rheumatic aortic valve diseases	0.001	0.998	0.000
H01.9 Inflammation of eyelid, unspecified	0.000	0.998	0.001
H01.8 Other specified inflammation of eyelid	0.000	0.998	0.001
H01.1 Non-infectious dermatoses of eyelid	0.000	0.998	0.001
H02.1 Ectropion of eyelid	0.000	0.998	0.002
I83.1 Varicose veins of lower extremities with inflammation	0.002	0.998	0.000
R19.5 Other fecal abnormalities	0.002	0.998	0.000
R49 Voice disturbances	0.001	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.001
I86.1 Scrotal varices	0.001	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.001	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.001	0.998	0.000
I97.1 Other functional disturbances following cardiac surgery	0.001	0.998	0.000
I97.0 Postcardiotomy syndrome	0.001	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.998	0.001
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.001	0.998	0.000
I05 Rheumatic mitral valve diseases	0.001	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.001	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.001	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.998	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.001	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.001	0.998	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.998	0.001
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.001
Z03.1 Observation for suspected malignant neoplasm	0.001	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.998	0.001
T93 Sequelae of injuries of lower limb	0.001	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.001	0.999	0.000
M47.9 Spondylosis, unspecified	0.000	0.999	0.001
R22.1 Localised swelling, mass and lump, neck	0.001	0.999	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.000	0.999	0.001
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.999	0.001
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.999	0.001
H02 Other disorders of eyelid	0.000	0.999	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.999	0.000
A41.4 Septicaemia due to anaerobes	0.000	0.999	0.001
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.999	0.001
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.999	0.001
F10.4 Withdrawal state with delirium	0.001	0.999	0.000
I86.4 Gastric varices	0.001	0.999	0.000
K29.5 Chronic gastritis, unspecified	0.000	0.999	0.001
D04 Carcinoma in situ of skin	0.000	0.999	0.001
I28 Other diseases of pulmonary vessels	0.001	0.999	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.000	0.999	0.001
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.001	0.999	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.999	0.001
M24.07 Loose body in joint (Ankle and foot)	0.001	0.999	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.999	0.001
D12.0 Caecum	0.001	0.999	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.999	0.001
D86 Sarcoidosis	0.001	0.999	0.000
I73 Other peripheral vascular diseases	0.001	0.999	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.999	0.001
I05.2 Mitral stenosis with insufficiency	0.001	0.999	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.999	0.000
I06.8 Other rheumatic aortic valve diseases	0.001	0.999	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.999	0.000
I06.1 Rheumatic aortic insufficiency	0.001	0.999	0.000
I06.0 Rheumatic aortic stenosis	0.001	0.999	0.000
I09.9 Rheumatic heart disease, unspecified	0.001	0.999	0.000
I09.8 Other specified rheumatic heart diseases	0.001	0.999	0.000
I09.2 Chronic rheumatic pericarditis	0.001	0.999	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.999	0.000
I09.0 Rheumatic myocarditis	0.001	0.999	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.001	0.999	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.999	0.001
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.999	0.001
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.999	0.000
R49.8 Other and unspecified voice disturbances	0.001	0.999	0.000
R49.2 Hypernasality and hyponasality	0.001	0.999	0.000
R49.1 Aphonia	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.999	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.999	0.001
D09.0 Bladder	0.000	0.999	0.001
G45.9 Transient cerebral ischaemic attack, unspecified	0.001	0.999	0.000
I05.8 Other mitral valve diseases	0.001	0.999	0.000
I05.1 Rheumatic mitral insufficiency	0.001	0.999	0.000
I05.0 Mitral stenosis	0.001	0.999	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.999	0.000
I07.8 Other tricuspid valve diseases	0.001	0.999	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.999	0.000
I07.0 Tricuspid stenosis	0.001	0.999	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.999	0.001
T92.0 Sequelae of open wound of upper limb	0.001	0.999	0.000
I71 Aortic aneurysm and dissection	0.001	0.999	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
D04.7 Skin of lower limb, including hip	0.000	0.999	0.001
D09.9 Carcinoma in situ, unspecified	0.000	0.999	0.001
D09.7 Carcinoma in situ of other specified sites	0.000	0.999	0.001
D09.3 Thyroid and other endocrine glands	0.000	0.999	0.001
D09.2 Eye	0.000	0.999	0.001
D09.1 Other and unspecified urinary organs	0.000	0.999	0.001
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.999	0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000
T93.0 Sequelae of open wound of lower limb	0.001	0.999	0.000
Z95.1 Presence of aortocoronary bypass graft	0.001	0.999	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.999	0.001
I83 Varicose veins of lower extremities	0.001	0.999	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.001	0.999	0.000
R60 Oedema, not elsewhere classified	0.000	0.999	0.001
H02.5 Other disorders affecting eyelid function	0.000	0.999	0.001
T92 Sequelae of injuries of upper limb	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.999	0.001
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
D00.2 Stomach	0.000	0.999	0.001
D00.1 Oesophagus	0.000	0.999	0.001
D00.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
D01.9 Digestive organ, unspecified	0.000	0.999	0.001
D01.7 Other specified digestive organs	0.000	0.999	0.001
D01.5 Liver, gallbladder and bile ducts	0.000	0.999	0.001
D01.4 Other and unspecified parts of intestine	0.000	0.999	0.001
D01.3 Anus and anal canal	0.000	0.999	0.001
D01.2 Rectum	0.000	0.999	0.001
D01.1 Rectosigmoid junction	0.000	0.999	0.001
D01.0 Colon	0.000	0.999	0.001
D02.4 Respiratory system, unspecified	0.000	0.999	0.001
D02.3 Other parts of respiratory system	0.000	0.999	0.001
D02.2 Bronchus and lung	0.000	0.999	0.001
D02.1 Trachea	0.000	0.999	0.001
D02.0 Larynx	0.000	0.999	0.001
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.999	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.999	0.001
H02.2 Lagophthalmos	0.000	0.999	0.001
J40 Bronchitis, not specified as acute or chronic	0.000	0.999	0.001
R47-R49 Symptoms and signs involving speech and voice	0.001	0.999	0.000
D04.9 Skin, unspecified	0.000	0.999	0.001
D04.8 Skin of other sites	0.000	0.999	0.001
D04.4 Skin of scalp and neck	0.000	0.999	0.001
D04.2 Skin of ear and external auricular canal	0.000	0.999	0.001
D04.1 Skin of eyelid, including canthus	0.000	0.999	0.001
D04.0 Skin of lip	0.000	0.999	0.001
I07.1 Tricuspid insufficiency	0.001	0.999	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.999	0.000
I28.8 Other specified diseases of pulmonary vessels	0.001	0.999	0.000
I28.1 Aneurysm of pulmonary artery	0.001	0.999	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.999	0.000
K65.0 Acute peritonitis	0.000	0.999	0.001
M31.6 Other giant cell arteritis	0.001	0.999	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.999	0.001
B37.0 Candidal stomatitis	0.000	0.999	0.001
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
F02.3 Dementia in Parkinson's disease	0.001	0.999	0.000
I73.8 Other specified peripheral vascular diseases	0.001	0.999	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.001	0.999	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.001	0.999	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.999	0.001
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.999	0.001
D51.2 Transcobalamin II deficiency	0.000	0.999	0.001
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.999	0.001
N48.6 Balanitis xerotica obliterans	0.001	0.999	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.001	0.999	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.999	0.001
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.999	0.000
F03 Unspecified dementia	0.001	0.999	0.000
I08 Multiple valve diseases	0.001	0.999	0.001
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.999	0.001
D04.5 Skin of trunk	0.000	0.999	0.001
H02.0 Entropion and trichiasis of eyelid	0.000	0.999	0.001
I05.9 Mitral valve disease, unspecified	0.001	0.999	0.000
I11 Hypertensive heart disease	0.001	0.999	0.000
A49.0 Staphylococcal infection, unspecified	0.001	0.999	0.000
D07.6 Other and unspecified male genital organs	0.000	0.999	0.001
D07.4 Penis	0.000	0.999	0.001
D07.3 Other and unspecified female genital organs	0.000	0.999	0.001
D07.2 Vagina	0.000	0.999	0.001
D07.0 Endometrium	0.000	0.999	0.001
E11.3 With ophthalmic complications	0.000	0.999	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.999	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.001	0.999	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.001	0.999	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.999	0.000
I78.1 Naevus, nonneoplastic	0.001	0.999	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.001	0.999	0.000
M24.0 Loose body in joint	0.001	0.999	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.001	0.999	0.000
H04 Disorders of lachrymal system	0.000	0.999	0.001
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.001	0.999	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.001	0.999	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.001	0.999	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.001	0.999	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.001	0.999	0.000
D03 Melanoma in situ	0.000	0.999	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.999	0.001
F06.7 Mild cognitive disorder	0.001	0.999	0.000
H02.8 Other specified disorders of eyelid	0.000	0.999	0.001
R22.2 Localised swelling, mass and lump, trunk	0.001	0.999	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations